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olfactory hallucination

Julie M Hall, Kaylena A Ehgoetz Martens, Courtney C Walton, Claire O'Callaghan, Peter E Keller, Simon J G Lewis, Ahmed A Moustafa
Parkinson's disease (PD) is a heterogeneous neurological disorder with a variety of motor and non-motor symptoms. The underlying mechanisms of these symptoms are not fully understood. An increased interest in structural connectivity analyses using diffusion tensor imaging (DTI) in PD has led to an expansion of our understanding of the impact of abnormalities in diffusivity on phenotype. This review outlines the contribution of these abnormalities to symptoms of PD including bradykinesia, tremor and non-tremor phenotypes, freezing of gait, cognitive impairment, mood, sleep disturbances, visual hallucinations and olfactory dysfunction...
September 28, 2016: Parkinsonism & related Disorders
Christopher Baethge, Michaela Jänner, Wolfgang Gaebel, Jaroslav Malevani
Hallucinations are at the core of the diagnosis of schizophrenia and schizoaffective disorders, and many neuroscience studies focus on hallucinations. However, there is a lack of data on prevalence, subtyping, and clinical correlates of hallucinations as well as on the comparison of hallucinating schizophrenia versus hallucinating schizoaffective patients. Analysis of all psychopathology evaluations is based on the AMDP scale in a German psychiatric university hospital between 2007 and 2013 regarding patients with schizophrenia or schizoaffective disorder (diagnosed according to ICD-10)...
October 17, 2016: European Archives of Psychiatry and Clinical Neuroscience
July Silveira Gomes, Henrique Akiba, Álvaro M Dias, Amanda Soares, Ivan Taiar, Ary A Gadelha, Quirino Cordeiro, Pedro Shiozawa
No abstract text is available yet for this article.
October 2016: Schizophrenia Research
Laiana Quagliato, Roberto Piedade, Cristina Santana, Elie Cheniaux
Although a variety of metabolic, toxic, psychiatric, and neurologic conditions can produce catatonic syndromes, it is less widely recognized that this state may be caused by epilepsy. We present the case of a woman with catatonic behavior, which she could not recall. She also exhibited olfactory, auditory and visual hallucinations. An EEG demonstrated diffuse abnormal electrical activity, mainly on left temporal and frontal areas. Treatment with anticonvulsant drugs yielded excellent response.
July 25, 2016: Clinical Schizophrenia & related Psychoses
Andrew H Evans, Chiun-Hian Chai
Background. Nonmotor symptoms particularly olfactory dysfunction, RBD, depression, hallucinations, and constipation are currently not included in the typical clinical criteria for diagnosing Lewy body Parkinsonian disorders (LBPD). The aim of this study is to determine the diagnostic value of nonmotor symptoms in patients presenting with Parkinsonism and tremor. Methods. All new patients seen between January 2007 and May 2013 in the Movement Disorders Specialist Clinics of the Royal Melbourne Hospital (RMH), who were referred with a possible neurodegenerative syndrome or concerns of Parkinsonism and/or tremor, were included...
2016: Parkinson's Disease
Katsuyuki Ukai, Hiroshige Fujishiro, Masako Watanabe, Kenji Kosaka, Norio Ozaki
Epilepsy with the main symptom of amnesia is known as transient epileptic amnesia (TEA). Dementia with Lewy bodies (DLB) is the second most common form of neurodegenerative dementia. The concept that Lewy body disease includes Parkinson's disease with dementia and dementia with Lewy bodies was proposed in the 2005 revision of the Clinical Diagnostic Criteria. Here, we describe a woman with cognitive impairment, olfactory dysfunction, and reduced (123) I-meta-iodobenzylguanidine uptake on myocardial scintigraphy...
June 30, 2016: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
Vina M Goghari, Martin Harrow
Hallucinations are a salient feature of both psychotic and mood disorders. Currently there is a call for more research on the phenomenology of different forms of hallucinations, in a broader array of disorders, to further both theoretical knowledge and clinical utility. We investigated auditory, visual, and olfactory hallucinations at index hospitalization and auditory and visual hallucinations prospectively for 20years in 150 young patients, namely 51 schizophrenia, 25 schizoaffective, 28 bipolar, and 79 unipolar depression...
October 2016: Schizophrenia Research
Anastasia Lim, Hans W Hoek, Mathijs L Deen, Jan Dirk Blom
BACKGROUND: Auditory hallucinations are experienced by 60-80% of all patients diagnosed with a schizophrenia spectrum disorder. However, in this patient group, the prevalence of hallucinations in multiple sensory modalities, i.e. multimodal hallucinations (MMHs), is unknown. AIMS: To assess the prevalence of MMHs in patients diagnosed with a schizophrenia spectrum disorder, data were analyzed from 750 patients who participated in the Dutch Genetic Risk and Outcome of Psychosis (GROUP) study...
October 2016: Schizophrenia Research
Michael Ronthal, Nagagopal Venna, George J Hunter, Matthew P Frosch
Presentation of Case. Dr. Ivana Vodopivec (Neurology): A 32-year-old man was seen in an outpatient clinic of this hospital because of olfactory hallucinations, intermittent numbness and paresthesias on the left side, and a mass in the right temporal lobe. The patient had been well until..
May 19, 2016: New England Journal of Medicine
David Kimhy
Olfactory hallucinations (OH) are experienced by a substantial minority of people with schizophrenia, often leading to social anxiety, depression and suffering. Yet, despite their prevalence and clinical significance, OH in schizophrenia are under-researched and poorly understood, with scarce information about potential treatments. To address this gap in the literature, the author describes a case report of successfully using Cognitive-Behavioral Therapy for psychosis (CBTp) to address OH, related delusions, as well as mood and social functioning difficulties in a male patient with schizophrenia...
2016: American Journal of Psychotherapy
Federico Mainardi, Alan Rapoport, Giorgio Zanchin, Ferdinando Maggioni
INTRODUCTION: Olfactory hallucination during a migraine attack (OHM) is a rare phenomenon. At present, it is not considered a manifestation of migraine aura. MATERIAL AND METHODS: The clinical features of OHM were collected in 11 patients. RESULTS: Of the 11 patients, 10 had migraine without aura and one migraine with aura associated with OHM. Mean age at onset of headache and at appearance of OHM were respectively 17.8 and 32.3 years. Migraine average frequency was 3...
March 31, 2016: Cephalalgia: An International Journal of Headache
Jörn Lötsch, Alfred Ultsch, Maren Eckhardt, Caroline Huart, Philippe Rombaux, Thomas Hummel
The presence of cerebral lesions in patients with neurosensory alterations provides a unique window into brain function. Using a fuzzy logic based combination of morphological information about 27 olfactory-eloquent brain regions acquired with four different brain imaging techniques, patterns of brain damage were analyzed in 127 patients who displayed anosmia, i.e., complete loss of the sense of smell (n = 81), or other and mechanistically still incompletely understood olfactory dysfunctions including parosmia, i...
2016: NeuroImage: Clinical
Eleanor Longden, Allan O House, Mitch G Waterman
Although repeated associations have been found between adversity exposure (particularly childhood sexual abuse), dissociation and auditory hallucinations in the context of psychosis, there is little comparable research examining hallucinations in other modalities. This study aimed to determine whether cumulative adversity exposure influences the likelihood of experiencing visual, tactile, olfactory and gustatory hallucinations amongst psychosis patients, and if measures of dissociation are significantly associated with non-auditory hallucinations when adjusting for exposure to childhood adversity, and psychological distress...
February 25, 2016: Journal of Trauma & Dissociation
Rochelle E Cox, Robyn A Langdon
Olfactory hallucinations (smelling odors that are not present) are intrusive and disruptive yet challenging to investigate because they cannot be produced on demand. In this study, the authors attempted to model olfactory hallucinations using hypnotic suggestions. We gave some subjects a suggestion to smell an odor in the absence of a real odor (positive hallucination) and gave others a suggestion to smell nothing in the presence of a real odor (negative hallucination). High hypnotizable individuals who received the positive hallucination reported intense smells whereas those who received the negative hallucination reported a reduction in intensity...
2016: International Journal of Clinical and Experimental Hypnosis
E Longden, M Sampson, J Read
BACKGROUND: This study examines relationships between childhood adversity and the presence of characteristic symptoms of schizophrenia. It was hypothesised that total adversity exposures would be significantly higher in individuals exhibiting these symptoms relative to patients without. Recent proposals that differential associations exist between specific psychotic symptoms and specific adversities was also tested, namely: sexual abuse and hallucinations, physical abuse and delusions, and fostering/adoption and delusions...
August 2016: Epidemiology and Psychiatric Sciences
Caitlin Ridgewell, Allison Bray, Kaylah Curtis, Kenia Velasquez, Philip R Baldwin, J Christopher Fowler, Sanjay J Mathew, Ramiro Salas
No abstract text is available yet for this article.
2015: Journal of Neuropsychiatry and Clinical Neurosciences
Nirendra Kumar Rai, Vinay Goyal, Nand Kumar, Garima Shukla, Achal Kumar Srivastava, Sumit Singh, Madhuri Behari
OBJECTIVE: To evaluate neuropsychiatric co-morbidities (depression, psychosis and anxiety) in non-demented patients with Parkinson's disease (PD). BACKGROUND: Non-motor symptoms like neuropsychiatric co-morbidities are common in Parkinson's disease and may predate motor symptoms. Currently there is scarcity of data regarding neuropsychiatry manifestations in Indian patients with PD. METHODS: In this cross-sectional study consecutive 126 non-demented patients with PD (MMSE ≥25) were enrolled...
January 2015: Annals of Indian Academy of Neurology
S-Y Cheah, B R Lawford, R M Young, C P Morris, J Voisey
BACKGROUND: Dystrobrevin binding protein 1 (DTNBP1) is a schizophrenia susceptibility gene involved with neurotransmission regulation (especially dopamine and glutamate) and neurodevelopment. The gene is known to be associated with cognitive deficit phenotypes within schizophrenia. In our previous studies, DTNBP1 was found associated not only with schizophrenia but with other psychiatric disorders including psychotic depression, post-traumatic stress disorder, nicotine dependence and opiate dependence...
June 2015: European Psychiatry: the Journal of the Association of European Psychiatrists
Paul C Donaghy, Ian G McKeith
Dementia with Lewy bodies (DLB) is the second most common type of degenerative dementia following Alzheimer's disease (AD). DLB is clinically and pathologically related to Parkinson's disease (PD) and PD dementia, and the three disorders can be viewed as existing on a spectrum of Lewy body disease. In recent years there has been a concerted effort to establish the phenotypes of AD and PD in the prodromal phase (before the respective syndromes of cognitive and motor impairment are expressed). Evidence for the prodromal presentation of DLB is also emerging...
2014: Alzheimer's Research & Therapy
I de Chazeron, B Pereira, I Chereau-Boudet, G Brousse, D Misdrahi, G Fénelon, A-M Tronche, R Schwan, C Lançon, A Marques, B Debilly, F Durif, P M Llorca
OBJECTIVE: If hallucinations are the most common of schizophrenic symptoms, they have been described in other pathologies such as Parkinson's disease (PD) but may differ considerably in their phenomenology. However, no multi-modal clinical scale with a transnosographic approach has been developed today. The purpose of this study was to create and validate a new tool for the hetero-assessment of all sensory modalities of hallucinations schizophrenia (SCZ) and in PD. METHOD: Scale items were generated by literature review and validated by medical board...
February 2015: Schizophrenia Research
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