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https://www.readbyqxmd.com/read/28637940/thoracoscopic-thymectomy-with-tangential-partial-resection-of-the-innominate-vein
#1
Motoki Yano, Katsuhiro Okuda, Osamu Kawano, Ayumi Suzuki, Risa Oda, Ryoichi Nakanishi, Masayuki Haniuda
We herein report a case in which thoracoscopic thymectomy with partial resection of the brachiocephalic vein was performed using a subxiphoid approach. We suggest the usefulness of the subxiphoid approach in thymectomy. We could extend the indications of thoracoscopic thymectomy for invasive tumors. Thoracoscopic thymectomy with the combined resection of part of the brachiocephalic vein was possible. The pathological diagnosis of the tumor was diffuse large cell B-cell lymphoma. Since the postoperative complications were minimal, postoperative adjuvant chemotherapy could be initiated without delay...
June 22, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28628938/outcome-after-robotic-assisted-thymectomy-in-children-and-adolescents-with-acetylcholine-receptor-antibody-positive-juvenile-myasthenia-gravis
#2
Adela Della Marina, Heike Kölbel, Maximilian Müllers, Olaf Kaiser, Mahmoud Ismail, Marc Swierzy, Jens-Carsten Rueckert, Ulrike Schara
No abstract text is available yet for this article.
June 19, 2017: Neuropediatrics
https://www.readbyqxmd.com/read/28624025/quantitative-computed-tomography-texture-analysis-for-estimating-histological-subtypes-of-thymic-epithelial-tumors
#3
Koichiro Yasaka, Hiroyuki Akai, Masanori Nojima, Aya Shinozaki-Ushiku, Masashi Fukayama, Jun Nakajima, Kuni Ohtomo, Shigeru Kiryu
OBJECTIVES: To investigate whether high-risk thymic epithelial tumor (TET) (HTET) can be differentiated from low-risk TET (LTET) using computed tomography (CT) quantitative texture analysis. MATERIALS AND METHODS: The data of 39 patients (mean age, 58.6±14.1 years) (39 unenhanced CT (UECT) and 33 contrast-enhanced CT (CECT)) who underwent thymectomy for TET were retrospectively analyzed. A region of interest was placed to include the entire TET within the slice at its maximum diameter...
July 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28619540/video-assisted-thoracic-surgery-thymectomy-versus-sternotomy-thymectomy-in-patients-with-thymoma
#4
Hiroyuki Agatsuma, Kazuo Yoshida, Ichiro Yoshino, Meinoshin Okumura, Masahiko Higashiyama, Kenji Suzuki, Masanori Tsuchida, Jitsuo Usuda, Hiroshi Niwa
BACKGROUND: This study was designed to evaluate the feasibility of video-assisted thoracoscopic surgery (VATS) and to compare the oncologic outcomes of VATS with those of sternotomy in patients with thymoma. METHODS: The clinical outcomes of 2,835 patients with thymic epithelial tumors treated between 1991 and 2010 in 32 Japanese institutions were collected retrospectively. The study compared postoperative complications, positive surgical margins, location of recurrence, and survival in 140 of 142 VATS-treated patients (VATS group) matched with 140 of 1,294 sternotomy-treated patients (ST group) by using propensity scores...
June 13, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28616293/video-assisted-thoracoscopic-completion-thymectomy-based-on-mediastinal-pleura-guidance
#5
Kai Guo, Liping Tong, Xiaofei Li, Xiaolong Yan
We describe a practical video-assisted thoracoscopic surgery (VATS) technique for the en bloc resection of the thymoma, thymus, and bilateral mediastinum lipid based on mediastinal pleura guidance. By taking advantage of single-lumen endotracheal tube (SLET) anesthesia and artificial pneumothorax, we acquired excellent exposure of the anterior mediastinum operative field. In addition, our limited data showed that this surgical approach might have a potential tendency on reducing the blood loss and the operative times...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28614249/thymectomy-via-open-surgery-or-robotic-video-assisted-thoracic-surgery-can-a-recommendation-already-be-made
#6
Judith Buentzel, Carmen Straube, Judith Heinz, Christian Roever, Alexander Beham, Andreas Emmert, Marc Hinterthaner, Bernhard C Danner, Alexander Emmert
BACKGROUND: Robot-assisted minimally invasive surgery (RVATS) is a relatively new technique applied for thymectomies. Only few studies directly compare RVATS to the mainstay therapy, open surgery (sternotomy). METHODS: A systematic search of the literature was performed in October 2016. The meta-analysis includes studies comparing robotassisted and open thymectomy regarding operation time, length of hospitalization, intraoperative blood loss, and chest-in-tube days, postoperative complications, reoperation, arrhythmic events, pleural effusion, and postoperative bleeding...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28605955/solitary-thymic-metastasis-of-breast-cancer-13-years-after-surgery
#7
Akira Fukunaga, Yuji Sasamura, Akio Takada, Yoshihiro Murakami, Hirotake Abe, Mamoru Miyasaka
A 59-year-old woman was noted to have an anterior mediastinal mass on computed tomography at a regular follow-up 13 years after initial surgery for left breast cancer. Magnetic resonance imaging showed an anterior mediastinal mass. A total thymectomy with excision of surrounding lymphoid tissue was performed. Pathological examination of the resected tumor confirmed the diagnosis of thymic metastasis from breast cancer. The patient has been alive for 6 years after thymectomy. Metastases to the thymus are rare, but long-term survival can be expected with appropriate treatment...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28604379/physiotherapy-immediately-after-thymectomy-in-patients-with-myasthenia-gravis-two-cases-and-review-of-the-literature
#8
Massimiliano Polastri, Franco Stella, Massimo Lambertini, Walter Trani, Annalisa Ghetti, Andrea Dell'Amore
AIM: Myasthenia gravis (MG) is a rare autoimmune disease characterized by activation of autoantibodies against acetylcholine receptors: patients with MG typically experience muscle weakness and fatigue. The aims of the present study were 1) to describe immediate postoperative physiotherapeutic interventions in two MG patients who underwent thymectomy, and 2) to discuss postoperative rehabilitative issues in MG patients. MATERIALS AND METHODS: This was a non-experimental study analyzing two subjects with MG who underwent thymectomy...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28592450/a-propensity-score-analysis-for-comparison-of-t-3b-and-vatet-in-myasthenia-gravis
#9
Greta Brenna, Carlo Antozzi, Cristina Montomoli, Fulvio Baggi, Renato Mantegazza
OBJECTIVE: We performed propensity score (PS) models to compare the outcome of patients with myasthenia gravis (MG) submitted to 2 different surgical approaches: extended transsternal (T-3b) or thoracoscopic extended thymectomy (VATET). METHODS: Patients' clinical data were retrieved from the MG database of the C. Besta Neurologic Institute Foundation. In the PS analysis, a matching ratio of 1:1 of the main clinical variables was obtained for the 2 groups of patients and treatment effect was estimated by comparing their outcome...
June 7, 2017: Neurology
https://www.readbyqxmd.com/read/28591868/video-assisted-thoracoscopic-thymectomy-for-non-thymomatous-myasthenia-gravis-a-right-sided-or-left-sided-approach
#10
Hany Hasan Elsayed, Mahmoud Gamal, Saleh Raslan, Hossam Abdel Hamid
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was in [patients undergoing video-assisted thoracoscopic thymectomy for myasthenia gravis (MG)] is a [left-sided approach] superior to a [right-sided approach] in terms of [clinical outcome]? Two hundred and fifty-nine papers were found using the reported search. In looking at both procedures, we selected studies with a sizeable number of patients performing or studying both procedures and comparing their outcome...
June 7, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28539430/physiologic-thymic-involution-underlies-age-dependent-accumulation-of-senescence-associated-cd4-t-cells
#11
Kyosuke Sato, Aiko Kato, Miho Sekai, Yoko Hamazaki, Nagahiro Minato
Immune aging may underlie various aging-related disorders, including diminished resistance to infection, chronic inflammatory disorders, and autoimmunity. PD-1(+) and CD153(+) CD44(high) CD4(+) T cells with features of cellular senescence, termed senescence-associated T (SA-T) cells, increasingly accumulate with age and may play a role in the immune aging phenotype. In this article, we demonstrate that, compared with young mice, the aged mouse environment is highly permissive for spontaneous proliferation of transferred naive CD4(+) T cells, and it drives their transition to PD-1(+) and CD153(+) CD44(high) CD4(+) T cells after extensive cell divisions...
May 24, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28535636/-characteristics-of-distribution-and-quantity-of-dendritic-cells-subtypes-in-hyperplastic-thymus-in-patients-with-myasthenia-gravis
#12
H Huang, P Chen, C Y Ou, L Qiu, Z Z Lin, Z D Huang, W B Liu
Objective: To investigate the characteristics of the distribution and amount of different subtypes of dendritic cell (DC) in myasthenia gravis(MG). Methods: We collected the thymic specimens from 32 patients who received thymoctomy because of cardiac surgery from January 2016 to December 2016 and selected 14 of them as normal control. Meantime, 61 MG patients who combined with thymic hyperplasia and received extended thymectomy were collected and selected 8 of them as experiment group.Immunohistochemical methods were used to label the two subtype DCs: plasmacytoid dendritic cell (pDC) and classical/conventional dendritic cell (cDC), to observe the distribution of these two DC subtypes in thymus and also quantify them in different thymus structures by image analysis software...
May 23, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28529813/difficult-management-of-a-double-lumen-endotracheal-tube-and-difficult-ventilation-during-robotic-thymectomy-with-carbon-dioxide-insufflation
#13
Yuki Sugiyama, Kunihiro Mitsuzawa, Yuki Yoshiyama, Fumiko Shimizu, Satoshi Fuseya, Takashi Ichino, Hiroyuki Agatsuma, Takayuki Shiina, Ken-Ichi Ito, Mikito Kawamata
Robotic surgery with carbon dioxide (CO2) insufflation to the thorax is frequently performed to gain a better operative field of view, although its intraoperative complications have not yet been discussed in detail. We treated two patients with difficult ventilation caused by distal migration of a double-lumen endotracheal tube (DLT) during robotic thymectomy. In the first case, migration of the DLT during one-lung ventilation (OLV) occurred after CO2 insufflation to the bilateral thoraxes was started. Oxygenation rapidly deteriorated because dependent lung expansion was restricted by CO2 insufflation...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28523161/the-safety-profile-of-preoperative-administration-of-heparin-for-thromboprophylaxis-in-chinese-patients-intended-for-thoracoscopic-major-thoracic-surgery-a-pilot-randomized-controlled-study
#14
Han-Yu Deng, Chang-Lin Shi, Gang Li, Jun Luo, Zhi-Qiang Wang, Yi-Dan Lin, Lun-Xu Liu, Qing-Hua Zhou
BACKGROUND: Patients undergoing major thoracic surgery especially for cancers are at a high risk of perioperative thromboembolism. Current guidelines recommended either heparin sodium (unfractionated heparin) or low-molecular-weight heparin (LMWH) for those patients at high risk of deep vein thrombosis (DVT). However, the rational timing of starting heparin has not yet been well established, because DVT can be caused by not only surgery but also comorbidities as well as prolonged hospital stay, and thoracic surgeons always concerned about heparin-related increased risk of intra- or post-operative bleeding...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28514336/-the-quality-of-life-in-patients-with-a-different-types-of-myasthenia-gravis
#15
Yu N Bykov, V I Okladnikov, A I Smolin
AIM: Researching quality of life in patients with myasthenia gravis at different clinical variants of disease. MATERIAL AND METHODS: We studied 103 patients with myasthenia gravis. A battery of tests and scales for assessment of neurological deficit and quality of life was used. RESULTS AND CONCLUSION: Two types of disease have been identified in myasthenia gravis: favorable and unfavorable. The minimal duration of disease before thymectomy is the main determinant of the best outcome...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28509648/video-assisted-extirpation-of-cranial-mediastinal-masses-in-dogs-18-cases-2009-2014
#16
Melissa A MacIver, J Brad Case, Eric L Monnet, Geraldine B Hunt, Philipp D Mayhew, Michelle L Oblak, Jeffrey J Runge, Ameet Singh, Daniel D Smeak, Michele A Steffey, Sarah E Boston
OBJECTIVE To characterize clinical findings, surgical procedures, complications, and outcomes in dogs undergoing extirpation of masses from the cranial mediastinum via video-assisted thoracic surgery (VATS) and establish preliminary guidelines for case selection when considering VATS for thymectomy in dogs. DESIGN Retrospective case series. ANIMALS 18 client-owned dogs that underwent extirpation of a cranial mediastinal mass by means of VATS at 5 academic referral hospitals from 2009 through 2014. PROCEDURES Medical records were reviewed and data extracted regarding signalment, clinical signs, physical examination findings, diagnostic imaging results, surgical approach and duration, cytologic and histologic examination results, complications, outcome, and cause of death, when applicable...
June 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28479053/thymectomy-and-myasthenia-gravis-a-history-of-surgical-passion-and-scientific-excellence
#17
EDITORIAL
Joshua R Sonett, Mitchell J Magee, Lyall Gorenstein
No abstract text is available yet for this article.
July 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28473943/cyclosporine-is-a-potential-curative-treatment-option-for-advanced-thymoma
#18
Yusuke Isshiki, Hiroaki Tanaka, Yoshio Suzuki, Yukihiro Yoshida
BACKGROUND: Thymectomy can effectively cure most thymoma patients; however, patients with advanced thymoma typically require chemotherapy, which is associated with limited efficacy in this context. Here we provide the first report of a patient with recurrent thymoma who achieved complete remission (CR) using cyclosporine therapy. CASE PRESENTATION: A 63-year-old woman who had undergone resection surgery for recurrent type B1 thymoma developed pure red cell aplasia (PRCA), and CT findings revealed thymoma recurrence...
2017: Experimental Hematology & Oncology
https://www.readbyqxmd.com/read/28471717/randomized-trial-of-thymectomy-in-myasthenia-gravis
#19
(no author information available yet)
New England Journal of Medicine, Volume 376, Issue 21, Page 2097-2097, May 2017.
May 25, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28457757/juvenile-myasthenia-gravis-in-norway-clinical-characteristics-treatment-and-long-term-outcome-in-a-nationwide-population-based-cohort
#20
T H Popperud, M I Boldingh, M Rasmussen, E Kerty
BACKGROUND: This study aimed to characterize juvenile myasthenia gravis in a national population-based cohort in Norway, and to evaluate long-term outcome and potential differences correlated with prepubertal versus postpubertal disease onset. PATIENTS AND METHODS: Patients with onset of myasthenia gravis aged ≤18 years were identified through multiple strategies. Retrospective clinical data were collected by means of medical charts. All patients had an updated clinical examination...
April 20, 2017: European Journal of Paediatric Neurology: EJPN
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