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https://www.readbyqxmd.com/read/29232903/pediatric-thermal-burns-and-treatment-a-review-of-progress-and-future-prospects
#1
REVIEW
Elton Mathias, Madhu Srinivas Murthy
Burn injuries are a devastating critical care problem. In children, burns continue to be a major epidemiologic problem around the globe resulting in significant morbidity and death. Apparently, treating these burn injuries in children and adults remains similar, but there are significant physiological and psychological differences. The dermal layer of the skin is generally thinner in neonates, infants, and children than in adults. Enhanced evaporative loss and need for isotonic fluids increases the risk of hypothermia in the pediatric population...
December 11, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29231870/improving-the-care-and-treatment-of-monkeypox-patients-in-low-resource-settings-applying-evidence-from-contemporary-biomedical-and-smallpox-biodefense-research
#2
REVIEW
Mary G Reynolds, Andrea M McCollum, Beatrice Nguete, Robert Shongo Lushima, Brett W Petersen
Monkeypox is a smallpox-like illness that can be accompanied by a range of significant medical complications. To date there are no standard or optimized guidelines for the clinical management of monkeypox (MPX) patients, particularly in low-resource settings. Consequently, patients can experience protracted illness and poor outcomes. Improving care necessitates developing a better understanding of the range of clinical manifestations-including complications and sequelae-as well as of features of illness that may be predictive of illness severity and poor outcomes...
December 12, 2017: Viruses
https://www.readbyqxmd.com/read/29231755/pharmaceutical-aspects-of-silver-nanoparticles
#3
Prateek Mathur, Swati Jha, Suman Ramteke, N K Jain
Silver nanoparticles are particles in the size ranging between 1 and 100 nm. The two major methods used for synthesis of silver nanoparticle are the physical and chemical methods with the disadvantage that they are expensive and can also have toxicity. Biological method is being used as an expedient alternative, as this approach is environment-friendly and less toxic and it includes plant extracts, microorganism, fungi, etc. The major applications of silver nanoparticles in the medical field include diagnostic applications and therapeutic applications, apart from its antimicrobial activity...
December 12, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29229195/a-comparison-of-two-different-fluid-resuscitation-management-protocols-for-pediatric-burn-patients-a-retrospective-study
#4
Miao Huang, Jun-Feng Chen, Li-Ying Chen, Li-Qin Pan, Xiao-Jian Li, Jie-Yu Ye, Hui-Yi Tan
OBJECTIVE: Pediatric burn patients are more susceptible to burn shock than adults, and an effective fluid management protocol is critical to successful resuscitation. Our research aim was to investigate the safety and efficacy of two protocols for pediatric burn patients for use within the first 24h. METHODS: A total of 113 pediatric burn patients were enrolled from January 2007 to October 2012. Of those patients, 57 received fluid titration regimens of alternating crystalloids and colloids once within 2h in the first 24h after burn (Group A), whereas the remaining patients received regimens of alternating crystalloids and colloids once within 1h in the first 24h after burn (Group B)...
December 8, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29224036/laser-advances-in-the-treatment-of-burn-and-traumatic-scars
#5
Shilpi Khetarpal, Urvashi Kaw, Jeffrey S Dover, Kenneth A Arndt
The realm of scar management is constantly changing. Many factors need to be considered when developing a comprehensive treatment plan, including the nature of the scar and the patient. Scar characteristics can be divided by color, scar type and thickness, and body location. Topical and intralesional agents and light- and laserbased treatments can be used to revitalize and restore damaged skin in atrophic and hypertrophic scars. The most commonly used lasers are the pulsed-dye laser (PDL) and fractional lasers...
December 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29223905/litter-removal-does-not-compensate-detrimental-fire-effects-on-biodiversity-in-regularly-burned-semi-natural-grasslands
#6
Orsolya Valkó, András Kelemen, Tamás Miglécz, Péter Török, Balázs Deák, Katalin Tóth, János Pál Tóth, Béla Tóthmérész
Regulation of plant biomass accumulation is a key issue in effective grassland conservation in Europe. Burning is an alternative tool to regulate biomass dynamics in semi-natural grasslands even in the absence of grazing or mowing. We tested the effects of regular spring burning on the biomass fractions and fine-scale plant species composition of species-rich foothill grasslands in North-Hungary. There were five regularly burned and five control grasslands in the study; we collected twenty 20×20-cm sized biomass samples from each...
December 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29216595/optimizing-prescribed-fire-allocation-for-managing-fire-risk-in-central-catalonia
#7
Fermín J Alcasena, Alan A Ager, Michele Salis, Michelle A Day, Cristina Vega-Garcia
We used spatial optimization to allocate and prioritize prescribed fire treatments in the fire-prone Bages County, central Catalonia (northeastern Spain). The goal of this study was to identify suitable strategic locations on forest lands for fuel treatments in order to: 1) disrupt major fire movements, 2) reduce ember emissions, and 3) reduce the likelihood of large fires burning into residential communities. We first modeled fire spread, hazard and exposure metrics under historical extreme fire weather conditions, including node influence grid for surface fire pathways, crown fraction burned and fire transmission to residential structures...
December 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29214186/a-rare%C3%A2-case-of%C3%A2-failed-healing-in-previously-burned-skin%C3%A2-after-a%C3%A2-secondary-burns
#8
Stephen J Goldie, Shaun Parsons, Hana Menezes, Andrew Ives, Heather Cleland
Background: Patients presenting with large surface area burns are common in our practice; however, patients with a secondary large burn on pre-existing burn scars and grafts are rare and not reported. Case presentation: We report on an unusual case of a patient sustaining a secondary large burn to areas previously injured by a burn from a different mechanism. We discuss the potential implications when managing a case like this and suggest potential biological reasons why the skin may behave differently...
2017: Burns and Trauma
https://www.readbyqxmd.com/read/29211657/open-to-air-is-a-viable-option-for-initial-wound-care-in-necrotizing-soft-tissue-infection-that-allows-early-detection-of-recurrence-without-need-for-painful-dressing-changes-or-return-to-operating-room
#9
Derek Yang, April Davies, Bailey Burge, Phillip Watkins, Sharmila Dissanaike
BACKGROUND: The standard treatment of necrotizing soft tissue infection (NSTI) includes extensive surgical debridement. Care of these debridements is challenging because of the size of the wound and associated pain. A potential solution is to leave the wounds open-to-air in the period after the initial debridement, allowing for regular inspection at bedside while reducing pain associated with frequent dressing changes. We evaluated the feasibility of this approach from a pain control standpoint...
December 6, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29209994/the-role-of-trypsin-chymotrypsin-in-tissue-repair
#10
REVIEW
Dilip Shah, Kushal Mital
Tissue damage of all types, such as surgical or accidental injuries, fractures, and burns, stimulates a well-orchestrated, physiological process of healing, which ultimately leads to structural and functional restoration of the damaged tissues. The tissue repair process can be broadly divided into four continuous and overlapping phases-hemostasis and coagulation, inflammation, proliferation, and remodeling. If the process is interrupted or halted during any stage, it leads to impaired healing and formation of a chronic wound...
December 5, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29207887/burn-care-and-rehabilitation-in-australia-health-professionals-perspectives
#11
Rachel Kornhaber, Greg Rickard, Loyola McLean, Rick Wiechula, Violeta Lopez, Michelle Cleary
OBJECTIVE: To understand health professionals' perspectives of burn care and rehabilitation. DESIGN: Qualitative and semi-structured interviews. SETTING: Australian burn and rehabilitation units. PARTICIPANTS: Twenty-two clinicians working in burns units across disciplines and healthcare settings. RESULTS: The data portrayed the health professionals' perspectives of burn care and rehabilitation in Australia...
December 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29204871/bone-marrow-mesenchymal-stem-cells-combat-lipopolysaccharide-induced-sepsis-in-rats-via-amendment-of-p38-mapk-signaling-cascade
#12
Omnia S Zaki, Marwa M Safar, Afaf A Ain-Shoka, Laila A Rashed
Sepsis is a systemic inflammatory disorder which often occurs during extremely stressful conditions such as trauma, burn, shock, and infection. This study investigated the curative effects of bone marrow-derived mesenchymal stem cells (BM-MSCs) against hepatic, renal, and pulmonary responses caused by a single administration of lipopolysaccharide (LPS) (10 mg/kg, i.p) in rats. Treatment with BM-MSCs (5 × 105 in 0.1 ml PBS, i.p.) 3 h after LPS antagonized the LPS-induced increment of the liver enzymes (ALT, AST) and kidney functions (BUN, sCr)...
December 4, 2017: Inflammation
https://www.readbyqxmd.com/read/29202605/toxic-epidermal-necrolysis-spectrum-management-at-sunnybrook-health-sciences-centre-our-multidisciplinary-approach-after-review-of-the-current-evidence
#13
Alexandra Mereniuk, Alejandra Jaque, Marc G Jeschke, Neil H Shear
Toxic epidermal necrolysis spectrum (TENS) is a rare yet severe adverse drug reaction associated with a high mortality rate. Beyond supportive care, there is still no established therapy for TENS, although recent meta-analyses and UK guideline recommendations have attempted to offer a review of relevant literature on this difficult topic. As most directed treatments lack clear consensual evidence, care centres often resort to establishing their own strategies. As Canada's largest adult burn centre and the provincial reference centre for most burn patients in Ontario, our team at the Ross Tilley Burn Centre, in collaboration with the Department of Dermatology at Sunnybrook Health Sciences Centre, Toronto, Canada, has managed over 60 confirmed cases of TENS over the past 2 decades...
December 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29200497/sweat-bees-on-hot-chillies-provision-of-pollination-services-by-native-bees-in-traditional-slash-and-burn-agriculture-in-the-yucat%C3%A3-n-peninsula-of-tropical-mexico
#14
Patricia Landaverde-González, José Javier G Quezada-Euán, Panagiotis Theodorou, Tomás E Murray, Martin Husemann, Ricardo Ayala, Humberto Moo-Valle, Rémy Vandame, Robert J Paxton
Traditional tropical agriculture often entails a form of slash-and-burn land management that may adversely affect ecosystem services such as pollination, which are required for successful crop yields. The Yucatán Peninsula of Mexico has a >4000 year history of traditional slash-and-burn agriculture, termed 'milpa'. Hot 'Habanero' chilli is a major pollinator-dependent crop that nowadays is often grown in monoculture within the milpa system.We studied 37 local farmers' chilli fields (sites) to evaluate the effects of landscape composition on bee communities...
December 2017: Journal of Applied Ecology
https://www.readbyqxmd.com/read/29196340/dynamics-of-gaps-vegetation-and-plant-species-with-and-without-fire
#15
Eric S Menges, Sarah J H Crate, Pedro F Quintana-Ascencio
PREMISE OF THE STUDY: Areas lacking dominant plants, or gaps, can support high diversity and specialist species. Previous chronosequence research in Florida rosemary scrub showed indistinct gap area patterns with fire and the dependence of certain species on gaps. We hypothesized that fire and gap size would affect extinction, colonization, diversity, and vegetation composition. METHODS: In 2011-12, we revisited gaps first sampled in 2003, recording vascular plant and ground lichen occurrence by species, gap area, and burn history...
December 1, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/29194773/plasma-il-8-signature-correlates-with-pain-and-depressive-symptomatology-in-patients-with-burning-mouth-syndrome-results-from-a-pilot-study
#16
Alison Barry, Ken D O'Halloran, Joseph P McKenna, Christine McCreary, Eric J Downer
BACKGROUND: Burning mouth syndrome (BMS) is a neuropathic orofacial pain condition of unknown aetiology that encompasses intra-oral burning pain without abnormal clinical findings. Psychological, neural and inflammatory processes are associated with BMS pathogenesis. Currently, studies characterising plasma cytokine/chemokine profiles with pain and depression in BMS patients are lacking. Considering that inflammation is associated with the pathophysiology of BMS, and that inflammation is closely associated with pain and depression, we aimed to correlate depressive symptomatology and oral cavity pain with plasma cytokine/chemokine signatures in a cohort of patients with BMS...
December 1, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29183637/cell-spray-auto-grafting-technology-for-deep-partial-thickness-burns-problems-and-solutions-during-clinical-implementation
#17
Roger Esteban-Vives, Alain Corcos, Myung S Choi, Matthew T Young, Patrick Over, Jenny Ziembicki, Jörg C Gerlach
Cell-spray autografting is an innovative early treatment option for deep partial-thickness burn wounds. As an alternative to non-operative management, cell-spray autografting can achieve rapid wound re-epithelialization, particularly in large wounds. When compared to traditional mesh autografting for deep partial-thickness burn wounds, cell-spray autografting can accomplish re-epithelialization with a much smaller donor site. In this review, we describe the development of a biomedical engineering method for isolation and immediate distribution of autologous, non-cultured, adult epidermis-, and adult dermis-derived stem cells...
November 25, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29182931/surveying-managers-to-inform-a-regionally-relevant-invasive-phragmites-australis-control-research-program
#18
C B Rohal, K M Kettenring, K Sims, E L G Hazelton, Z Ma
Managers of invasive species consider the peer-reviewed literature only moderately helpful for guiding their management programs. Though this "knowing-doing gap" has been well-described, there have been few efforts to guide scientists in how to develop useful and usable science. Here we demonstrate how a comprehensive survey of managers (representing 42 wetland management units across the Great Salt Lake watershed) can highlight management practices and challenges (here for the widespread invasive plant, Phragmites australis, a recent and aggressive invader in this region) to ultimately inform a research program...
November 24, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29180925/marjolin-s-ulcer-in-chronic-wounds-review-of-available-literature
#19
REVIEW
Dariusz Bazaliński, Joanna Przybek-Mita, Beata Barańska, Paweł Więch
Marjolin's ulcer is a rare, aggressive skin cancer developing in scar tissue, chronic ulcers and areas affected by inflammations. Its incidence is estimated to range from 1% to 2% of all burn scars. It most frequently takes the form of squamous cell carcinoma which sometimes is diagnosed during examination of lesions developing in scars and hard-to-heal chronic wounds (pressure sores, leg ulcers). Therapeutic management of Marjolin's ulcer requires well-designed treatment plan to ensure optimal medical care and good quality of life for the patient...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29180911/burning-mouth-syndrome-aetiopathogenesis-and-principles-of-management
#20
REVIEW
L Feller, J Fourie, M Bouckaert, R A G Khammissa, R Ballyram, J Lemmer
Burning mouth syndrome (BMS) is a chronic debilitating oral condition characterised by a burning sensation of the oral mucosa in an otherwise apparently normal person. Its aetiology and pathogenesis are obscure, but both psychogenic factors and peripheral and central neuropathies appear to be implicated. There is no cure for BMS, and treatment with either local or systemic medications focuses on the relief of symptoms and on improving quality of life. In recalcitrant cases, psychological/psychiatric intervention may be helpful...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
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