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https://www.readbyqxmd.com/read/29468586/a-rat-burn-injury-model-for-studying-changes-in-microvascular-permeability
#1
Katie Wiggins-Dohlvik, Binu Tharakan
The management of burn patients is an extremely complex and clinically challenging for patient care. Aside from the increasing reports of burn injury and morbidity and mortality directly related to it, the pathobiology of burn trauma is not clearly understood. The rat model of burn trauma described here is currently used in research laboratories to study various aspects of burn injury, including vascular dysfunctions. This model demonstrates the infliction of thermal injury in Sprague-Dawley rats using a well-established boiled water approach...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29467914/comprehensive-review-and-case-study-on-the-management-of-buried-penis-syndrome-and-related-panniculectomy
#2
Hadley Burns, J Stephen Gunn, Saeed Chowdhry, Thomas Lee, Steven Schulz, Bradon J Wilhelmi
Objective: This paper discusses the various surgical techniques and outcomes associated with management of buried penis syndrome. Methods: Presented is the case of a 49-year-old man with morbid obesity, leading to massive panniculus and buried penis. We review our technique for reconstruction of the buried penis and treatment of the overlying large panniculus. Literature search was conducted to review current techniques in correcting buried penis syndrome. Results: The patient underwent a successful panniculectomy with removal of all excess skin and tissue...
2018: Eplasty
https://www.readbyqxmd.com/read/29461292/inhalation-injury-in-the-burned-patient
#3
Guillermo Foncerrada, Derek M Culnan, Karel D Capek, Sagrario González-Trejo, Janos Cambiaso-Daniel, Lee C Woodson, David N Herndon, Celeste C Finnerty, Jong O Lee
Inhalation injury causes a heterogeneous cascade of insults that increase morbidity and mortality among the burn population. Despite major advancements in burn care for the past several decades, there remains a significant burden of disease attributable to inhalation injury. For this reason, effort has been devoted to finding new therapeutic approaches to improve outcomes for patients who sustain inhalation injuries.The three major injury classes are the following: supraglottic, subglottic, and systemic. Treatment options for these three subtypes differ based on the pathophysiologic changes that each one elicits...
February 15, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29454710/experiences-of-guilt-shame-and-blame-in-those-affected-by-burns-a-qualitative-systematic-review
#4
REVIEW
Rachel Kornhaber, Charmaine Childs, Michelle Cleary
BACKGROUND: A significant burn can severely impact the lives of survivors and their carers. This systematic review sought to incorporate the experiences of guilt, blame and shame across the lifespan for burn survivors, their families as well as the experiences of the parents of burned children. METHODS: A systematic review of qualitative studies on the experiences and perspectives of guilt, blame and shame by those affected by burn trauma across the lifespan. The databases, Pubmed, Scopus, EMBASE, CINAHL, PsychINFO were systematically searched...
February 14, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29453974/genetically-modified-bone-mesenchymal-stem-cells-with-tgf-%C3%AE-3-improve-wound-healing-and-reduce-scar-tissue-formation-in-a-rabbit-model
#5
Mingyong Li, Lin Qiu, Wei Hu, Xiang Deng, Hanfeng Xu, Youhan Cao, Zijian Xiao, Liangyu Peng, Shawn Johnson, Lyundup Alexey, Paul A Kingston, Qing Li, Yuanyuan Zhang
Extensive scar tissue formation often occurs after severe burn injury, trauma, or as one of complications after surgical intervention. Despite significant therapeutic advances, it is still a significant challenge to manage massive scar tissue formation while also promoting normal wound healing. The goal of this study was to investigate the therapeutic effect of bone mesenchymal stem cells (BMSCs) that were genetically modified to overexpress transforming growth factor-beta 3 (TGF-β 3 ), an inhibitor of myofibroblast proliferation and collagen type I deposition, on full-thickness cutaneous wound healing in a rabbit model...
February 14, 2018: Experimental Cell Research
https://www.readbyqxmd.com/read/29448257/nonbacterial-thrombotic-endocarditis-presenting-with-leg-pain-and-a-left-atrial-mass-lesion
#6
Ahmed A Abouarab, Adham Elmously, Jeremy R Leonard, Mohammed J Arisha, Mario Gaudino, Naveent Narula, Arash Salemi
Systemic lupus erythematosus (SLE) is a major cause of nonbacterial thrombotic endocarditis (NBTE) associated with intracardiac sterile vegetations. It is rare for vegetations to present as an atrial tumor. This report describes a 48-year-old female with SLE and antiphospholipid syndrome complicated by recurrent thrombosis on anticoagulation. A large left atrial mass lesion was detected on echocardiography during a work-up for leg burning. Infective endocarditis could not be confirmed, and hence left atrial mass lesion was the most likely diagnosis...
February 15, 2018: Cardiology
https://www.readbyqxmd.com/read/29440796/tobacco-pouch-keratosis-in-a-young-individual-a-brief-description
#7
Preethy Mary Donald, George Renjith, Ankita Arora
Smokeless tobacco is used orally or nasally without burning tobacco. This is equally harmful as smokers due to the tobacco content and can cause oral cancer as well as systemic effects such as nicotinic dependence. Many other oral conditions have also been reported in association with smokeless tobacco. This paper presents features of tobacco pouch keratosis and aims to highlight the oral effects of smokeless tobacco, management, and guidelines for dentists in educating and counselling tobacco users.
May 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29438815/new-onset-squamous-cell-carcinoma-in-previous-split-thickness-skin-graft-donor-site
#8
Vincent J Noori, Kanika Trehan, Alisa Savetamal, Damien W Carter
INTRODUCTION: Marjolin' s ulcer, an aggressive ulcerating squamous cell carcinoma, is a well-known phenomenon that occurs in chronically inflamed or scarred tissue; however, squamous cell carcinoma arising in the acute setting after tissue trauma - specifically autograft donor harvest sites for burns - is a rare, but notable event. METHODS: This case series describes three instances of squamous cell carcinoma diagnosed in split-thickness skin graft donor sites in the immediate post-operative period...
February 10, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29432722/the-clinical-assessment-of-spasticity-in-people-with-spinal-cord-damage-recommendations-from-the-ability-network-an-international-initiative
#9
Anand V Nene, Alexandre Rainha Campos, Klemen Grabljevec, Arminda Lopes, Bengt Skoog, Anthony S Burns
A thorough assessment of the extent and severity of spasticity, and its impact on functioning, is central to the effective management of spasticity in persons with spinal cord damage (SCD). These individuals, however, do not always receive adequate assessment of their spasticity. Inadequate assessment compromises management when the impact of spasticity and/or need for intervention are not fully recognized. Assessment is also central to determining treatment efficacy. A barrier to spasticity assessment has been the lack of consensus on clinical and functional measures suitable for routine clinical practice...
February 9, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29428347/optimizing-the-management-of-spasticity-in-people-with-spinal-cord-damage-a-clinical-care-pathway-for-assessment-and-treatment-decision-making-from-the-ability-network-an-international-initiative
#10
Indira Lanig, Peter New, Anthony S Burns, Gerald Bilsky, Jesus Benito-Penalva, Djamel Bensmail, Michael Yochelson
The recognition, evaluation and management of disabling spasticity in persons with spinal cord damage (SCD) is a challenge for healthcare providers, health systems and patients. To guide the assessment and management of disabling spasticity in individuals with SCD, the Ability Network, an international panel of clinical experts, developed a clinical care pathway. The aim of this pathway is to facilitate treatment decisions that take into account the impact of disabling spasticity on health status, individual preferences and treatment goals, tolerance for adverse events, and burden on caregivers...
February 8, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29427056/a-rare-case-of-anal-and-perianal-chemical-burn-in-a-child-due-to-potassium-permanganate-crystals
#11
Suvashis Dash, Jatin Bhojani, Sharadendu Sharma
Many chemicals used as medical treatments can cause chemical burns as an untoward side effect. One of such chemicals is potassium permanganate. It is a caustic chemical used as a disinfectant. The most common sites of burn by potassium permanganate are exposed sites like the face and hands. Chemical burns in the perianal and anal region are rare in clinical practice and even sparser in the pediatric age group. In this article, we report a case of perianal and anal chemical burn in an 18-month-old, male child, caused by potassium permanganate crystal applied wrongly for the treatment of pinworm infestation...
February 9, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29426175/modeling-crop-residue-burning-experiments-to-evaluate-smoke-emissions-and-plume-transport
#12
Luxi Zhou, Kirk R Baker, Sergey L Napelenok, George Pouliot, Robert Elleman, Susan M O'Neill, Shawn P Urbanski, David C Wong
Crop residue burning is a common land management practice that results in emissions of a variety of pollutants with negative health impacts. Modeling systems are used to estimate air quality impacts of crop residue burning to support retrospective regulatory assessments and also for forecasting purposes. Ground and airborne measurements from a recent field experiment in the Pacific Northwest focused on cropland residue burning was used to evaluate model performance in capturing surface and aloft impacts from the burning events...
January 30, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29425875/burn-wound-healing-potential-of-a-polysaccharide-from-sanguisorba-officinalis-l-in-mice
#13
Hongfang Zhang, Junjie Chen, Ying Cen
Sanguisorba officinalis L. is widely used in China to treat various wounds, particularly burns. The present study was carried to evaluate the healing efficacy of a purified polysaccharide (SOP) from the roots of S. officinalis L. on burn wound models in mice. The results indicated that oral administration of SOP (50 and 200 mg/kg) significantly stimulated wound contraction and reduced epithelialization time as compared to control group, which might be mediated by promoting collagen synthesis as evidenced by an increase of hydroxyproline content...
February 6, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29423461/how-to-perform-contrast-enhanced-ultrasound-ceus
#14
REVIEW
Christoph F Dietrich, Michalakis Averkiou, Michael Bachmann Nielsen, Richard G Barr, Peter N Burns, Fabrizio Calliada, Vito Cantisani, Byung Choi, Maria C Chammas, Dirk-André Clevert, Michel Claudon, Jean-Michel Correas, Xin-Wu Cui, David Cosgrove, Mirko D'Onofrio, Yi Dong, JohnR Eisenbrey, Teresa Fontanilla, Odd Helge Gilja, Andre Ignee, Christian Jenssen, Yuko Kono, Masatoshi Kudo, Nathalie Lassau, Andrej Lyshchik, Maria Franca Meloni, Fuminori Moriyasu, Christian Nolsøe, Fabio Piscaglia, Maija Radzina, Adrian Saftoiu, Paul S Sidhu, Ioan Sporea, Dagmar Schreiber-Dietrich, Claude B Sirlin, Maria Stanczak, Hans-Peter Weskott, Stephanie R Wilson, Juergen Karl Willmann, Tae Kyoung Kim, Hyun-Jung Jang, Alexandar Vezeridis, Sue Westerway
"How to perform contrast-enhanced ultrasound (CEUS)" provides general advice on the use of ultrasound contrast agents (UCAs) for clinical decision-making and reviews technical parameters for optimal CEUS performance. CEUS techniques vary between centers, therefore, experts from EFSUMB, WFUMB and from the CEUS LI-RADS working group created a discussion forum to standardize the CEUS examination technique according to published evidence and best personal experience. The goal is to standardise the use and administration of UCAs to facilitate correct diagnoses and ultimately to improve the management and outcomes of patients...
January 2018: Ultrasound International Open
https://www.readbyqxmd.com/read/29422437/effect-of-cold-pack-therapy-for-management-of-burn-scar-pruritus-a-pilot-study
#15
So Young Joo, June-Bum Kim, Yoon Soo Cho, Yong Suk Cho, Cheong Hoon Seo
PURPOSE: Pruritus, a common, chronically disabling condition is often refractory to treatment. The pruritus sensation is mediated in the spinal cord and post-burn pruritus is considered a form of neuropathic pain. We investigated cold pack therapy as a treatment modality for post-burn pruritus. METHODS: We studied 23 patients with severe pruritus scoring at least 5 on the visual analogue scale (VAS) and refractory to antihistamine and gabapentin administration. Each cold pack therapy lasted more than 20min...
February 5, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29420818/multi-locus-sequence-typing-provides-epidemiological-insights-for-diseased-sharks-infected-with-fungi-belonging-to-the-fusarium-solani-species-complex
#16
Guillaume Desoubeaux, Anne Debourgogne, Nathan P Wiederhold, Marie Zaffino, Deanna Sutton, Rachel E Burns, Salvatore Frasca, Michael W Hyatt, Carolyn Cray
Fusarium spp. are saprobic moulds that are responsible for severe opportunistic infections in humans and animals. However, we need epidemiological tools to reliably trace the circulation of such fungal strains within medical or veterinary facilities, to recognize environmental contaminations that might lead to infection and to improve our understanding of factors responsible for the onset of outbreaks. In this study, we used molecular genotyping to investigate clustered cases of Fusarium solani species complex (FSSC) infection that occurred in eight Sphyrnidae sharks under managed care at a public aquarium...
October 9, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29415103/thermocouple-probe-orientation-affects-prescribed-fire-behavior-estimation
#17
T Adam Coates, Alex T Chow, Donald L Hagan, Thomas A Waldrop, G Geoff Wang, William C Bridges, Mary-Frances Rogers, James H Dozier
Understanding the relationship between fire intensity and fuel mass is essential information for scientists and forest managers seeking to manage forests using prescribed fires. Peak burning temperature, duration of heating, and area under the temperature profile are fire behavior metrics obtained from thermocouple-datalogger assemblies used to characterize prescribed burns. Despite their recurrent usage in prescribed burn studies, there is no simple protocol established to guide the orientation of thermocouple installation...
January 2018: Journal of Environmental Quality
https://www.readbyqxmd.com/read/29413607/development-of-nanoparticles-from-natural-lipids-for-topical-delivery-of-thymol-investigation-of-its-anti-inflammatory-properties
#18
Thais P Pivetta, Sandra Simões, Margarete M Araújo, Tânia Carvalho, Caroline Arruda, Priscyla D Marcato
Wound healing involves the integration of biological and molecular events and, in case of chronic wounds, the use of drugs can be associated to side effects. Therefore, there is a search for alternatives therapeutics that encompass minimal toxicity. The use of natural compounds is an attractive approach for treating inflammatory disorders, wounds and burns. In this context, thymol has antimicrobial, antioxidant and antiseptic properties and is a promising compound in wound healing and inflammation management...
January 31, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29406300/a-retrospective-cost-minimization-analysis-of-disposable-and-traditional-negative-pressure-wound-therapy-medicare-paid-claims
#19
Gary Delhougne, Christopher Hogan, Kim Tarka, Sunitha Nair
Traditional negative pressure wound therapy (NPWT) systems are considered durable. The pump is designed for use by numerous patients over a period of several years. Recently developed smaller, disposable devices are designed for single-patient use. A retrospective analysis of 2012-2014 national Medicare claims data was used to examine payments associated with the use of traditional and disposable NPWT systems. Data extracted included NPWT episodes from the Limited Data Set Standard Analytic Files including the 5% sample for traditional NPWT and 100% sample for disposable NPWT...
January 2018: Ostomy/wound Management
https://www.readbyqxmd.com/read/29406110/source-apportionment-of-pm2-5-light-extinction-in-an-urban-atmosphere-in-china
#20
Zijuan Lan, Bin Zhang, Xiaofeng Huang, Qiao Zhu, Jinfeng Yuan, Liwu Zeng, Min Hu, Lingyan He
Haze in China is primarily caused by high pollution of atmospheric fine particulates (PM2.5). However, the detailed source structures of PM2.5 light extinction have not been well established, especially for the roles of various organic aerosols, which makes haze management lack specified targets. This study obtained the mass concentrations of the chemical compositions and the light extinction coefficients of fine particles in the winter in Dongguan, Guangdong Province, using high time resolution aerosol observation instruments...
January 2018: Journal of Environmental Sciences (China)
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