keyword
https://read.qxmd.com/read/38641681/author-correction-early-gastric-cancer-detection-and-lesion-segmentation-based-on-deep-learning-and-gastroscopic-images
#1
Kezhi Zhang, Haibao Wang, Yaru Cheng, Hongyan Liu, Qi Gong, Qian Zeng, Tao Zhang, Guoqiang Wei, Zhi Wei, Dong Chen
No abstract text is available yet for this article.
April 19, 2024: Scientific Reports
https://read.qxmd.com/read/38629273/prognostic-impact-of-left-atrial-appendage-patency-after-device-closure
#2
JOURNAL ARTICLE
Mu Chen, Peng-Cheng Yao, Zhen-Tao Fei, Qun-Shan Wang, Yi-Chi Yu, Peng-Pai Zhang, Wei Li, Rui Zhang, Bin-Feng Mo, Ming-Zhe Zhao, Yi Yu, Mei Yang, Yan Zhao, Chang-Qi Gong, Jian Sun, Yi-Gang Li
BACKGROUND: The prognostic impact of left atrial appendage (LAA) patency, including those with and without visible peri-device leak (PDL), post-LAA closure in patients with atrial fibrillation, remains elusive. METHODS: Patients with atrial fibrillation implanted with the WATCHMAN 2.5 device were prospectively enrolled. The device surveillance by cardiac computed tomography angiography was performed at 3 months post-procedure. Adverse events, including stroke/transient ischemic attack (TIA), major bleeding, cardiovascular death, all-cause death, and the combined major adverse events (MAEs), were compared between patients with complete closure and LAA patency...
April 17, 2024: Circulation. Cardiovascular Interventions
https://read.qxmd.com/read/38570595/early-gastric-cancer-detection-and-lesion-segmentation-based-on-deep-learning-and-gastroscopic-images
#3
JOURNAL ARTICLE
Kezhi Zhang, Haibao Wang, Yaru Cheng, Hongyan Liu, Qi Gong, Qian Zeng, Tao Zhang, Guoqiang Wei, Zhi Wei, Dong Chen
Gastric cancer is a highly prevalent disease that poses a serious threat to public health. In clinical practice, gastroscopy is frequently used by medical practitioners to screen for gastric cancer. However, the symptoms of gastric cancer at different stages of advancement vary significantly, particularly in the case of early gastric cancer (EGC). The manifestations of EGC are often indistinct, leading to a detection rate of less than 10%. In recent years, researchers have focused on leveraging deep learning algorithms to assist medical professionals in detecting EGC and thereby improve detection rates...
April 3, 2024: Scientific Reports
https://read.qxmd.com/read/38563770/synthesis-structures-and-properties-of-trioxa-9-circulene-and-diepoxycyclononatrinaphthalene
#4
JOURNAL ARTICLE
Daiyue Yang, Ka Man Cheung, Qi Gong, Li Zhang, Lulin Qiao, Xiao Chen, Zhifeng Huang, Qian Miao
This article presents trioxa[9]circulene (3) as a novel member of hetero[n]circulenes. Its synthesis began with the synthesis of dimethoxydioxa[8]helicene (5) and used dimethoxydiepoxycyclononatrinaphthalene (4) as a key intermediate, despite the condensation reaction predominantly yielding a 1,4-addition byproduct. The structures and properties of 3-5 were extensively investigated using experimental and computational methods. Analysis of the crystal structures reveal elongation of the internal C-C bonds in the nine-membered ring of 3 compared to 4 and 5...
April 2, 2024: Angewandte Chemie
https://read.qxmd.com/read/38509432/treatment-of-multisystem-inflammatory-syndrome-in-children
#5
REVIEW
Tong Tong, Yi-Hua Jin, Min Wang, Fang-Qi Gong
BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), a relatively uncommon but severe pediatric complication, is associated with coronavirus disease 2019 (COVID-19). A variety of treatment approaches, including intravenous immunoglobulins (IVIGs), glucocorticoids (GCs) and biologic agents, such as anakinra and infliximab, have been described for the management of COVID-19-related MIS-C. Anticoagulant therapy is also important. However, a well-developed treatment system has not been established, and many issues remain controversial...
March 21, 2024: World Journal of Pediatrics: WJP
https://read.qxmd.com/read/38486485/fasn-inhibition-decreases-mhc-i-degradation-and-synergizes-with-pd-l1-checkpoint-blockade-in-hepatocellular-carcinoma
#6
JOURNAL ARTICLE
Jiao Huang, Wai Ying Tsang, Xiao-Na Fang, Yu Zhang, Jie Luo, Lan-Qi Gong, Bai-Feng Zhang, Ching Ngar Wong, Zhi-Hong Li, Bei-Lei Liu, Jin-Lin Huang, Yu-Ma Yang, Shan Liu, Liu-Xian Ban, Yiu Hong Chan, Xin-Yuan Guan
UNLABELLED: Immune checkpoint inhibitors (ICI) transformed the treatment landscape of hepatocellular carcinoma (HCC). Unfortunately, patients with attenuated MHC-I expression remain refractory to ICIs, and druggable targets for upregulating MHC-I are limited. Here, we found that genetic or pharmacologic inhibition of fatty acid synthase (FASN) increased MHC-I levels in HCC cells, promoting antigen presentation and stimulating antigen-specific CD8+ T-cell cytotoxicity. Mechanistically, FASN inhibition reduced palmitoylation of MHC-I that led to its lysosomal degradation...
March 15, 2024: Cancer Research
https://read.qxmd.com/read/38366962/echinacoside-exerts-antihepatic-fibrosis-effects-in-high-fat-mice-model-by-modulating-the-acvr2a-smad-pathway
#7
JOURNAL ARTICLE
Jie Liang, Ting Chen, Honglei Xu, Tingfang Wang, Qi Gong, Tingting Li, Xiaoyan Liu, Jing Wang, Yun Wang, Liyan Xiong
SCOPE: Nonalcoholic steatohepatitis (NASH) is an increasingly common chronic liver disease in which hepatic fibrosis is the major pathological change. The transforming growth factor β (TGF-β)/mall mothers against decapentaplegic (Smad) signaling is the main effector of fibrosis. Although the antifibrotic effect of echinacoside (Ech) on the liver has been indicated previously, the cellular and molecular mechanisms remain unclear. This study aims to investigate both in vivo and in vitro antifibrotic properties of Ech...
February 17, 2024: Molecular Nutrition & Food Research
https://read.qxmd.com/read/38313401/a-prospective-study-of-the-effects-of-general-anesthesia-on-intraocular-pressure-in-healthy-children
#8
JOURNAL ARTICLE
Julius T Oatts, Shiya Shen, Hui Zhu, Qi Gong, Yinxi Yu, Gui-Shuang Ying, Ying Han, Hu Liu
PURPOSE: To determine the effect of general anesthesia on intraocular pressure (IOP) in children with no intraocular pathology and determine which postanesthetic time point is most predictive of preinduction IOP. DESIGN: Prospective observational study. PARTICIPANTS: Children with no intraocular pathology ≤ 18 years scheduled for general anesthesia as part of their routine care followed by a pediatric ophthalmologist at Nanjing Medical University...
2024: Ophthalmol Sci
https://read.qxmd.com/read/38243739/implementation-of-virtual-integrative-oncology-shared-medical-appointment-series-viosmas-within-mixed-diagnosis-population
#9
JOURNAL ARTICLE
Michelle H Loy, Lauren Prisco, Chiti Parikh
BACKGROUND: Integrative oncology [IO] is sought-after by patients, endorsed by clinical guidelines, and valued within National Cancer Institute Centers. Shared Medical Appointments [SMA] leverage health education and social connection to deliver enhanced patient experience, population health, cost-reduction, and clinician well-being. Integrative Oncology Shared Medical Appointments increase access to integrative medicine but delivering these services via telehealth have not been evaluated...
2024: Integrative Cancer Therapies
https://read.qxmd.com/read/38238692/regulation-of-btb-poz-structural-domain-6b-by-microrna-222b-in-zebrafish-embryos-after-exposure-to-di-2-ethylhexyl-phthalate-at-low-concentrations
#10
JOURNAL ARTICLE
Ge Huang, Qi Gong, Kai Zhang, Hossam El Din H Abdelhafez, Junjie Yu, Jiangfeng Guo
Di-(2-ethylhexyl) phthalate (DEHP) is a sort of endocrine disruptor that induces abnormal physiological and biochemical activities such as epigenetic alterations, apoptosis, and oxidative stress. MicroRNAs (miRNAs) are a class of short noncoding RNAs that may regulate the expression of many protein-coding genes when organisms are exposed to environmental chemicals. miR-222b is a differentially expressed miRNA after DEHP exposure. miRNA-mRNA prediction suggested that BTB (POZ) structural domain 6b ( BTBD6B ) might be a target mRNA of miR-222b, and DEHP exposure altered its expression...
January 18, 2024: Chemical Research in Toxicology
https://read.qxmd.com/read/38216454/-remote-sensing-model-for-estimating-atmospheric-pm-2-5-concentration-in-the-guangdong-hong-kong-macao-greater-bay-area
#11
JOURNAL ARTICLE
Yuan-Yuan Dai, Shao-Qi Gong, Cun-Jie Zhang, Ai-Lian Min, Hai-Jun Wang
PM2.5 is extremely harmful to the atmospheric environment and human health, and a timely and accurate understanding of PM2.5 with high spatial and temporal resolution plays an important role in the prevention and control of air pollution. Based on multi-angle implementation of atmospheric correction algorithm (MAIAC), 1 km AOD products, ERA5 meteorological data, and pollutant concentrations (CO, O3 , NO2 , SO2 , PM10 , and PM2.5 ) in the Guangdong-Hong Kong-Macao Greater Bay Area during 2015-2020, a geographically and temporally weighted regression model (GTWR), BP neural network model (BPNN), support vector machine regression model (SVR), and random forest model (RF) were established, respectively, to estimate PM2...
January 8, 2024: Huan Jing Ke Xue= Huanjing Kexue
https://read.qxmd.com/read/38197439/unravelling-the-role-of-mind-body-therapies-in-paediatric-palliative-care-a-narrative-review
#12
REVIEW
Luca Giacomelli, Simonetta Papa, Lara Vecchi, Anna Mercante, Franca Benini
AIM: Given the multifaceted nature of paediatric palliative care (PPC), integrative medicine and mind-body therapies, in particular, are increasingly used in this setting. However, to our knowledge, their use in PPC has never been specifically reviewed. Therefore, this work aims to provide a comprehensive overview of the application and possible beneficial effects of mind-body therapies in the PPC setting. METHODS: Papers about the use of meditation and mindfulness, biofeedback, hypnosis, yoga, tai chi and qi gong, imagery, creative outlets, and art therapy in PPC were identified by browsing PubMed and CINHAL...
January 10, 2024: Acta Paediatrica
https://read.qxmd.com/read/38151418/cul4b-enhances-the-malignant-phenotype-of-esophageal-squamous-cell-carcinoma-by-suppressing-tgfbr3-expression
#13
Qi Gong, Yuxing Wang, Kexin Zhu, Xueli Bai, Tong Feng, Gongping Sun, Molin Wang, Xiaohua Pan, Chengyong Qin
No abstract text is available yet for this article.
December 26, 2023: Biochemical and Biophysical Research Communications
https://read.qxmd.com/read/38092700/aromatic-hydrocarbon-based-and-space-interactions-induced-color-tunable-single-component-organic-phosphorescence
#14
JOURNAL ARTICLE
Weitao Sun, Ruikang Duan, Xianyin Dai, Lin Liu, Jinwei Li, Qi Gong, Guiyun Duan, Yanqing Ge
Construction of new system and exploration of new approach are of great importance for the improvement of their photophysical properties to meet the growing various uses of phosphorescent materials. Triphenylmethane (TPM), composed only of carbon and hydrogen, exhibits excellent color tunable phosphorescence in air, with ultralong lifetime (836 ms), and wide color-tunable range (from cyan to green, then to yellow and finally to orange, 525 nm-616 nm). Through careful comparison with the single crystal diffraction structure of tetraphenylmethane (TTPM) and theoretical calculation analysis, we believe that various clusters formed through space interactions are crucial for color-tunable phosphorescence...
December 13, 2023: Chemistry, An Asian Journal
https://read.qxmd.com/read/37990192/echocardiographic-measurements-of-left-ventricular-dimensions-and-function-in-newborns-with-omphalocele-and-pulmonary
#15
JOURNAL ARTICLE
Si-Si Yang, Wen-Chang Huang, Peng Wang, Fang-Qi Gong, Tai-Xiang Liu, Jin-Fa Tou, Deng-Ming Lai
PURPOSE: The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). METHODS: This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth...
November 22, 2023: BMC Pediatrics
https://read.qxmd.com/read/37876610/imperceptible-body-transformation-in-virtual-reality-saliency-of-self-representation
#16
JOURNAL ARTICLE
Gizem Senel, Francisco Macia-Varela, Jaime Gallego, Hatice Pehlivan Jensen, Kasper Hornbæk, Mel Slater
Change blindness (CB) is the perceptual phenomenon whereby people are blind to dramatic changes in their visual environment. In virtual reality (VR) a person's body can be substituted by a life-sized virtual one that moves synchronously with their real body movements as their self-representation. We consider whether CB occurs in VR, and whether there are differences in the case of changes to their own virtual body compared with the body of another. Forty people took part in a Qi Gong lesson in VR led by a virtual instructor...
October 20, 2023: IScience
https://read.qxmd.com/read/37741135/using-telehealth-to-deliver-qi-gong-and-tai-chi-programs-a-mixed-methods-systematic-review-on-feasibility-acceptability-and-participant-engagement-factors
#17
REVIEW
Junsheng L Teo, Stephen R Bird, Xiaoqiu Wang, Zhen Zheng
INTRODUCTION: Due to the COVID-19 pandemic, the use of digitally delivered exercise classes to promote physical activity has become widespread amongst various populations as an alternative to in-person activities. OBJECTIVES: To examine the feasibility, acceptability, and participant engagement variables to delivering Qi Gong and Tai Chi programs through telehealth interventions. METHODS: Ten databases (Seven English databases; three Chinese databases) were searched between October and November 2021...
September 17, 2023: Archives of Gerontology and Geriatrics
https://read.qxmd.com/read/37728995/densely-functionalized-macrocyclic-sesquiterpene-pyridine-alkaloids-from-maytenus-austroyunnanensis
#18
JOURNAL ARTICLE
Kai-Long Ji, Yao-Yue Fan, Qi Gong, Qun-Fang Liu, Ming-Jun Cui, Kai-Cong Fu, Hai-Yan Zhang, Jian-Min Yue
Eleven densely functionalized new dihydro-β-agarofuran sesquiterpenoid derivatives, named maytenoids A-K ( 1 - 11 ), as well as one known analog, were isolated and characterized from Maytenus austroyunnanensis . Their structures were assigned based on analysis of spectroscopic data and X-ray crystallography. Compounds 1 - 9 are macrocyclic sesquiterpene pyridine alkaloids generated by the respective acylation of the hydroxy groups at C-3 and C-13 of dihydro-β-agarofuran sesquiterpenoids via diverse pyridine dicarboxylic acids...
September 20, 2023: Journal of Natural Products
https://read.qxmd.com/read/37704682/fam3-family-genes-are-associated-with-prognostic-value-of-human-cancer-a-pan-cancer-analysis
#19
JOURNAL ARTICLE
Qing-Tai Dong, Dan-Dan Ma, Qi Gong, Zhen-Yu Lin, Zhong-Hu Li, Jia-Xin Ye, Chun-Hui Qin, Wei-Dong Jin, Jian-Xin Zhang, Zhi-Yong Zhang
Family with sequence similarity three member (FAM3) plays a crucial role in the malignant development of various cancers of human. However, there remains doubtful what specific role of FAM3 family genes in pan-cancer. Our study aimed to investigate the role of FAM3 family genes in prognosis, immune subtype, tumor immune microenvironment, stemness score, and anticancer drug sensitivity of pan-cancer. We obtained data from UCSC Xena GDC and CellMiner databases, and used them to study the correlation of the expression, survival, immune subtype, tumor microenvironment, stemness score, and anticancer drug sensitivity between FAM3 family genes with pan-cancer...
September 13, 2023: Scientific Reports
https://read.qxmd.com/read/37689324/traditional-uses-phytochemistry-pharmacology-applications-and-quality-control-of-gastrodia-elata-blume-a-comprehensive-review
#20
REVIEW
Meng-Qi Gong, Fei-Fan Lai, Jian-Zhen Chen, Xiao-Hong Li, Ya-Jie Chen, Yu He
ETHNOPHARMACOLOGICAL RELEVANCE: Gastrodia elata Blume (G. elata) has a long historical application in Asian countries and its tubers, seeds, and stalks are capable of being utilized for medicine, food, or health care products. AIM OF THE REVIEW: This study aimed to offer a systematic and up-to-date analysis of the current review of the G. elata research advances in traditional uses, phytochemistry, pharmacology, applications, and quality control, as well as a scientific reference for the development and utilization of this plant...
September 7, 2023: Journal of Ethnopharmacology
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