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Ying-Hui Jin, Guo-Hao Wang, Yi-Rong Sun, Qi Li, Chen Zhao, Ge Li, Jin-Hua Si, Yan Li, Cui Lu, Hong-Cai Shang
OBJECTIVE: To assess the methodology and quality of evidence of systematic reviews and meta-analyses of traditional Chinese medical nursing (TCMN) interventions in Chinese journals. These interventions include acupressure, massage, Tai Chi, Qi Gong, electroacupuncture and use of Chinese herbal medicines-for example, in enemas, foot massage and compressing the umbilicus. DESIGN: A systematic literature search for systematic reviews and meta-analyses of TCMN interventions was performed...
November 14, 2016: BMJ Open
Signe S Risom, Ann-Dorthe Zwisler, Pernille P Johansen, Kirstine L Sibilitz, Jane Lindschou, Christian Gluud, Rod S Taylor, Jesper H Svendsen, Selina K Berg
BACKGROUND: Exercise-based cardiac rehabilitation may benefit adults with atrial fibrillation or those who had been treated for atrial fibrillation. Atrial fibrillation is caused by multiple micro re-entry circuits within the atrial tissue, which result in chaotic rapid activity in the atria. OBJECTIVES: To assess the benefits and harms of exercise-based rehabilitation programmes, alone or with another intervention, compared with no-exercise training controls in adults who currently have AF, or have been treated for AF...
February 9, 2017: Cochrane Database of Systematic Reviews
Yan Wang, Guang Zhi Chen, Yan Yao, Yang Bai, Hui Min Chu, Ke Zhong Ma, Reginald Liew, Hao Liu, Guo Qiang Zhong, Yu Mei Xue, Shu Lin Wu, Yi Fu Li, Chun Xia Zhao, Qi Gong Liu, Li Lin, Lin Wang, Dao Wen Wang
The efficacy of a completely zero-fluoroscopy (ZF) approach for the catheter ablation of idiopathic ventricular arrhythmias (VAs) and whether it has advantages over the conventional fluoroscopy (F) approach are still unknown. The aim of this study was to compare the safety and efficacy of a completely ZF approach with those of the conventional F approach in the ablation of idiopathic VAs.We conducted a prospective study involving 7 centers in China. Consecutive patients (n = 489, mean age 45.3 ± 15...
February 2017: Medicine (Baltimore)
Lei Zhu, Bo-Xiang Qi, Dai-Hua Fang, Gong-Jian Qi, Kun Gao, Bao-Li Hu
OBJECTIVE: To study the clinical effect and mechanism of action of esmolol in the treatment of severe hand, foot, and mouth disease (HFMD). METHODS: A prospective randomized controlled trial was performed. A total of 102 children with severe HFMD were enrolled in the study and were randomly divided into conventional treatment and esmolol treatment groups (n=51 each). The children in the conventional treatment group were given conventional treatment according to the guidelines for the diagnosis and treatment of HFMD...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Hong-Wei Pan, Hong-Jun Lei, Xiao-Song He, Bei-Dou Xi, Yu-Ping Han, Qi-Gong Xu
To study the influence of long-term pesticide application on the distribution of organochlorine pesticides (OCPs) in the soil-groundwater system, 19 soil samples and 19 groundwater samples were collected from agricultural area with long-term pesticide application history in Northern China. Results showed that the composition of OCPs changed significantly from soil to groundwater. For example, ∑DDT, ∑HCH, and ∑heptachlor had high levels in the soil and low levels in the groundwater; in contrast, endrin had low level in the soil and high level in the groundwater...
April 2017: Environmental Geochemistry and Health
Peter Przekop, Allison Przekop, Mark G Haviland
Chronic tension-type headache (CTTH) in children and adolescents is a serious medical condition, with considerable morbidity and few effective, evidence-based treatments. We performed a chart review of 83 adolescents (age range = 13-18 years; 67 girls and 16 boys) diagnosed with CTTH. Two treatment protocols were compared: multimodal (osteopathic manipulative treatments, mindfulness, and qi gong) and pharmacologic (amitriptyline or gabapentin). Four outcomes (headache frequency, pain intensity, general health, and health interference) were assessed at three time points (baseline, 3 months, and 6 months)...
October 2016: Journal of Bodywork and Movement Therapies
Cheng-Rang Li, Hui Li, Rui-Xing Yu, Zhi-Liang Li, Qi Li, Juan-Qin Gong
No abstract text is available yet for this article.
September 2016: Cutis; Cutaneous Medicine for the Practitioner
Hai-Qi Zhang, Fei-Hu Gong, Ji-Qing Ye, Chi Zhang, Xiao-Hong Yue, Chuan-Gui Li, Yun-Gen Xu, Li-Ping Sun
EGFR and VEGFR-2 are involved in pathological disorders and the progression of different kinds of tumors, the combined blockade of EGFR and VEGFR signaling pathways appears to be an attractive approach to cancer therapy. In this work, a series of 4-anilinoquinazoline derivatives containing substituted diaryl urea or glycine methyl ester moiety were designed and identified as EGFR and VEGFR-2 dual inhibitors. Compounds 19i, 19j and 19l exhibited the most potent inhibitory activities against EGFR (IC50 = 1 nM, 78 nM and 51 nM, respectively) and VEGFR-2 (IC50 = 79 nM, 14 nM and 14 nM, respectively), they showed good antiproliferative activities as well...
January 5, 2017: European Journal of Medicinal Chemistry
Weidong Wang, Fang Wang, Feng Fan, Ana Cristina Sedas, Jian Wang
PURPOSE: The aim of this study is to identify and assess evidence related to the efficacy of mind-body interventions on irritable bowel syndrome (IBS) in the Chinese population. METHOD: Drawn from Chinese databases, nine RCTs and three Q-E studies were included in the systematic review. The methodological quality of RCTs was evaluated based on the following criteria: adequate sequence generation, allocation concealment, blinding, completeness of outcome data, selective reporting, and other potential biases...
September 19, 2016: International Journal of Behavioral Medicine
Benjamin Kligler, Raymond Teets, Melissa Quick
Significant evidence supports the effectiveness and safety of several complementary or integrative treatment approaches to common primary care problems. Acupuncture is effective in the management of chronic low back pain. Mind-body interventions such as cognitive behavior therapy, yoga, tai chi, qi gong, and music therapy may be helpful for treating insomnia. Exercise can reduce anxiety symptoms. Herbal preparations and nutritional supplements can be useful as first-line therapy for certain conditions, such as fish oil for hypertriglyceridemia, St...
September 1, 2016: American Family Physician
Liang Wen, Chao Liang, Enjiang Chen, Wei Chen, Feng Liang, Xiao Zhi, Tao Wei, Fei Xue, Guogang Li, Qi Yang, Weihua Gong, Xinhua Feng, Xueli Bai, Tingbo Liang
Hepatocellular carcinoma (HCC) is notoriously refractory to chemotherapy because of its tendency to develop multi-drug resistance (MDR), whose various underlying mechanisms make it difficult to target. The calcium signalling pathway is associated with many cellular biological activities, and is also a critical player in cancer. However, its role in modulating tumour MDR remains unclear. In this study, stimulation by doxorubicin, hypoxia and ionizing radiation was used to induce MDR in HCC cells. A sustained aggregation of intracellular calcium was observed upon these stimuli, while inhibition of calcium signalling enhanced the cells' sensitivity to various drugs by attenuating epithelial-mesenchymal transition (EMT), Hif1-α signalling and DNA damage repair...
March 24, 2016: Scientific Reports
Xiao-Yu Lu, Jing-Hui Liu, Xi Lu, Zheng-Qi Zhang, Tian-Jun Gong, Bin Xiao, Yao Fu
A Ni-catalyzed Markovnikov hydroalkylation of alkynes with alkyl halides is described. The reaction proceeds smoothly without the use of sensitive organometallic reagents and shows good functional-group compatibility, enabling the efficient synthesis of a variety of 1,1-disubstituted olefins. It also provides a straightforward approach for the modification of complex organic molecules.
April 18, 2016: Chemical Communications: Chem Comm
Ahmed Ebrahim-Alkhalil, Zhen-Qi Zhang, Tian-Jun Gong, Wei Su, Xiao-Yu Lu, Bin Xiao, Yao Fu
Herein, we describe a novel copper-catalyzed epoxide opening reaction with gem-diborylmethane. Aliphatic, aromatic epoxides as well as aziridines are converted to the corresponding γ-pinacolboronate alcohols or amines in moderate to excellent yields. This new reaction provides beneficial applications for classic epoxide substrates as well as interesting gem-diborylalkane reagents.
April 7, 2016: Chemical Communications: Chem Comm
Yin-Hing Ma, Qi Wang, Joshua Gong, Xiao Yu Wu
Owing to proliferation of antibiotic-resistant bacteria, the use of antibiotics for livestock growth promotion is banned in many countries and alternatives to in-feed antibiotics are needed. Cinnamon essential oil exhibits strong in vitro antibacterial activity; however, direct addition of essential oils to animal feed has limited practicality due to their high volatility, odor, fast decomposition, and poor availability in the lower intestines. To solve these problems, we formulated trans-cinnamaldehyde (CIN) with an adsorbent powder and fatty acid via a melt-solidification technique...
March 2016: Journal of Pharmaceutical Sciences
Fang Wang, Othelia Eun-Kyoung Lee, Fan Feng, Michael V Vitiello, Weidong Wang, Herbert Benson, Gregory L Fricchione, John W Denninger
The purpose of this systematic review was to identify and assess evidence related to the efficacy of meditative movement (MM) on sleep quality. We conducted a comprehensive review of relevant studies drawn from English and Chinese databases. Only randomized controlled trials (RCTs) reporting outcomes of the effects of MM (tai chi, qi gong, and yoga) on sleep quality were taken into consideration. Twenty-seven RCTs fulfilled our inclusion criteria and formed the basis for this review. Due to clinical heterogeneity, no meta-analysis was performed...
December 2016: Sleep Medicine Reviews
Fen Wang, Ze-Yi Liu, You-You Xia, Chong Zhou, Xiao-Ming Shen, Xiang-Li Li, Shu-Guang Han, Yan Zheng, Zhong-Qi Mao, Fei-Ran Gong, Min Tao, Lian Lian, Wei Li
The aim of the study was to investigate the application value of neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) in the prediction of chemotherapy response and prognosis in patients with advanced gastric cancer. In total, 120 patients with unresectable gastric cancer were included and separated into two groups according to the median values of NLR or PLR (NLR low: <4.62 or NLR high: ≥4.62 and PLR low: <235 or PLR high: ≥235, respectively). Low baseline NLR level correlated with improved clinicopathological characteristics, including smaller tumor size, well differentiation and less metastasis...
December 2015: Oncology Letters
Pu-Wei Hou, Pin-Kuei Fu, Hsin-Cheng Hsu, Ching-Liang Hsieh
To evaluate whether the use of traditional Chinese medicine (TCM; zhōng yī) influences symptoms or functional outcomes in patients with osteoarthritis (OA) of the knee ( xī guān jié yán). A systematic review of randomized control trials was conducted. Searches for studies in PubMed that were performed between 1965 and August 2013, and retrieved studies were subjected to reference screening. The types of studies included in our review were 1) placebo-based or comparative studies; 2) open label, single-blinded or double-blinded studies; 3) studies evaluating the efficacy of TCM for treating OA of the knee; and 4) studies evaluating only TCM or combination preparations...
October 2015: Journal of Traditional and Complementary Medicine
Zeng-Xin Qi, Jia-Jun Cai, Ling-Chao Chen, Qi Yue, Yan Gong, Yu Yao, Ying Mao
Tripartite motif (TRIM) proteins are involved in tumorigenesis. Here, we examined the expression, biological function, and clinical significance of tripartite motif containing 28 (TRIM28) in glioma, a locally aggressive brain tumor. First, TRIM28 expression was significantly higher in glioma (n = 138) than in non-glioma controls (n = 6). TRIM28 expression was positively correlated with tumor malignancy, and associated with poor overall survival (OS) and progression-free survival (PFS). Notably, TRIM28 expression was negatively correlated with p21 expression in patients with glioblastoma multiforme (GBM)...
January 2016: Journal of Neuro-oncology
Lian Lian, You-You Xia, Chong Zhou, Xiao-Ming Shen, Xiang-Li Li, Shu-Guang Han, Yan Zheng, Zhong-Qi Mao, Fei-Ran Gong, Meng-Yao Wu, Kai Chen, Min Tao, Wei Li
BACKGROUND: Gastric cancer is the fourth most frequent cancer and the second cause of cancer-related deaths worldwide. China has a high incidence of gastric cancer. Inflammation is a critical component of tumor progression. It has been widely accepted that gastric cancer is an inflammation-driven cancer. In this study, we investigated the application value of systemic inflammatory response (SIR) markers, platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR), in early diagnosis and prognostic prediction in patients with resectable gastric cancer...
2015: Cancer Biomarkers: Section A of Disease Markers
Qi Wang, Yubing Gong, Yanan Wu
Introducing adaptive coupling in delayed neuronal networks and regulating the dissipative parameter (DP) of adaptive coupling by noise, we study the effect of fluctuations of the changing rate of adaptive coupling on the synchronization of the neuronal networks. It is found that time delay can induce synchronization transitions for intermediate DP values, and the synchronization transitions become strongest when DP is optimal. As the intensity of DP noise is varied, the neurons can also exhibit synchronization transitions, and the phenomenon is delay-dependent and is enhanced for certain time delays...
November 2015: Bio Systems
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