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https://www.readbyqxmd.com/read/28718779/a-review-and-experimental-study-on-application-of-classifiers-and-evolutionary-algorithms-in-eeg-based-brain-machine-interface-systems
#1
Farajollah Tahernezhad-Javazm, Vahid Azimirad, Maryam Shoaran
OBJECTIVE: Considering the importance and the near future development of noninvasive Brain-Machine Interface (BMI) systems, this paper presents a comprehensive theoretical-experimental survey on the classification and evolutionary methods for BMI-based systems in which EEG signals are used. APPROACH: The paper is divided into two main parts. In the first part a wide range of different types of the base and combinatorial classifiers including boosting and bagging classifiers and also evolutionary algorithms are reviewed and investigated...
July 18, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28716617/dignity-therapy-and-life-review-for-palliative-care-patients-a-qualitative-study
#2
Dean Vuksanovic, Heather Green, Shirley Morrissey, Sharelle Smith
CONTEXT: Dignity Therapy (DT) is a psychotherapeutic intervention whose aim is to bolster the sense of purpose, meaning and sense of dignity in patients with terminal disease. OBJECTIVES: The aim of this study was to explore, compare and better understand the content of standard DT, waitlist DT (WDT) and Life Review (LR) that utilised the DT interview protocol but omitted the creation of legacy documents. METHODS: Efficacy of these interventions was previously documented in a sample of 56 participants...
July 14, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28714727/the-prospective-relationship-between-distress-tolerance-and-cigarette-smoking-expectancies-in-adolescence
#3
Julia M Shadur, Andrew L Ninnemann, Aaron Lim, Carl W Lejuez, Laura MacPherson
The current study examined the prospective relationship between distress tolerance (DT) and positive and negative cigarette smoking outcome expectancies, which are reliable predictors of the onset and maintenance of smoking behaviors. Data from a longitudinal study (N = 204) examining risk behaviors in adolescence were used to assess whether DT predicts individual differences in rate of change in smoking outcome expectancies over 4 annual assessment waves through adolescence. Adolescents (mean age at first wave: 13...
July 17, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/28713581/short-term-elevation-in-dietary-protein-intake-does-not-worsen-insulin-resistance-or-lipids-in-older-adults-with-metabolic-syndrome-a-randomized-controlled-trial
#4
Il-Young Kim, Scott E Schutzler, Gohar Azhar, Robert R Wolfe, Arny A Ferrando, Robert H Coker
BACKGROUND: There is a great deal of controversy as to whether higher protein intake improves or worsens insulin sensitivity in humans. The purpose of the study was to determine the influence of a short-term elevation in dietary protein on hepatic and peripheral insulin sensitivity in twelve older subjects (51-70 yrs) with metabolic syndrome. METHODS: Individuals were randomly assigned to one of the dietary groups: recommended protein intake (RPI, 10% of daily calorie intake) or elevated protein intake (EPI, 20% of daily calorie intake) for 4 weeks...
2017: BMC Nutrition
https://www.readbyqxmd.com/read/28713474/plantar-pressure-differences-between-nordic-walking-techniques
#5
Alberto Encarnación-Martínez, Ángel Gabriel Lucas-Cuevas, Pedro Pérez-Soriano, Ruperto Menayo, Gemma María Gea-García
High plantar pressure has been associated with increased risk of injury. The characteristics of each physical activity determine the load on the lower limbs. The influence of Nordic Walking (NW) technique on plantar pressure is still unknown. The aim of this study was to analyze the differences between plantar pressure during NW with the Diagonal technique (DT) versus Alpha technique (AT) and compare them with the pressure obtained during normal walking (W). The normality and sphericity of the plantar pressure data were checked before performing a two-way repeated measures ANOVA in order to find differences between speeds (preferred, fast) and the gait (NW, W) as within-subject factors...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28712343/overload-from-anxiety-a-non-motor-cause-for-gait-impairments-in-parkinson-s-disease
#6
Kaylena A Ehgoetz Martens, Carolina R A Silveira, Brittany N Intzandt, Quincy J Almeida
Threatening situations lead to observable gait deficits in individuals with Parkinson's disease (PD) who suffer from high trait anxiety levels. The specific characteristics of gait that are affected appear to be similar to behaviors observed while walking during a dual-task (DT) condition. Yet, it remains unclear whether anxiety is similar to a cognitive load. If it were, then those with PD who have high trait anxiety might be expected to be more susceptible to DT interference during walking. Thus, the overall aim of this study was to evaluate whether trait anxiety influences gait during single-task (ST) and DT walking...
July 17, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28711755/palliative-care-clinicians-caring-for-patients-before-and-after-continuous-flow-left-ventricular-assist-device
#7
Sara E Wordingham, Colleen K McIlvennan, Timothy J Fendler, Amy L Behnken, Shannon M Dunlay, James N Kirkpatrick, Keith M Swetz
Left ventricular assist devices (LVADs) are an available treatment option for carefully-selected patients with advanced heart failure. Initially developed as a bridge to transplantation, LVADs are now also offered to patients ineligible for transplantation as destination therapy (DT). Individuals with a DT-LVAD will live the remainder of their lives with the device in place. While survival and quality of life improve with LVADs compared to medical therapy, complications persist including bleeding, infection, and stroke...
July 12, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28710009/mrna-interactome-capture-in-mammalian-cells
#8
Nicolai Kastelic, Markus Landthaler
Throughout their entire life cycle, mRNAs are associated with RNA-binding proteins (RBPs), forming ribonucleoprotein (RNP) complexes with highly dynamic compositions. Their interplay is one key to control gene regulatory mechanisms from mRNA synthesis to decay. To assay the global scope of RNA-protein interactions, we and others have published a method combining crosslinking with highly stringent oligo(dT) affinity purification to enrich proteins associated with polyadenylated RNA (poly(A)+ RNA). Identification of the poly(A)+ RNA-bound proteome (also: mRNA interactome capture) has by now been applied to a diversity of cell lines and model organisms, uncovering comprehensive repertoires of RBPs and hundreds of novel RBP candidates...
July 11, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28710002/diphtheria-toxoid-and-n-trimethyl-chitosan-layer-by-layer-coated-ph-sensitive-microneedles-induce-potent-immune-responses-upon-dermal-vaccination-in-mice
#9
Pim Schipper, Koen van der Maaden, Vincent Groeneveld, Mitchel Ruigrok, Stefan Romeijn, Sven Uleman, Cees Oomens, Gideon Kersten, Wim Jiskoot, Joke Bouwstra
Dermal immunization using antigen-coated microneedle arrays is a promising vaccination strategy. However, reduction of microneedle sharpness and the available surface area for antigen coating is a limiting factor. To overcome these obstacles, a layer-by-layer coating approach can be applied onto pH-sensitive microneedles. Following this approach, pH-sensitive microneedle arrays (positively charged at coating pH5.8 and nearly uncharged at pH7.4) were alternatingly coated with negatively charged diphtheria toxoid (DT) and N-trimethyl chitosan (TMC), a cationic adjuvant...
July 11, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28707746/gas-evolution-in-activated-carbon-based-supercapacitors-using-protic-deep-eutectic-solvent-as-electrolyte
#10
Satyajit Phadke, Samia Amara, Meriem Anouti
One of the primary causes of ageing in supercapacitors are the irreversible faradaic reactions occurring near the operating voltage limit which lead to the production of gases resulting in device swelling, increased resistance (ESR), and lowering of the capacitance. In this study, we report a investigation of a protic "Deep Eutectic Solvent" (DES) consisting on mixture of Lithium bis(fluorosulfonyl)imide salt (LiFSI) with formamide (FMD) as H-bond donor (xLiFSI = 0.25 ; C = 2.5 M LiFSI) as electrolyte for AC based EDLC...
July 14, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28706555/advances-in-iron-chelation-therapy-transitioning-to-a-new-oral-formulation
#11
Nirmish R Shah
Iron overload is a concern for patients who require repeated red-blood-cell transfusions due to conditions such as sickle cell disease, thalassemia, or myelodysplastic syndromes. The recommended treatment for removing excess iron in these patients is iron chelation therapy. Currently available iron chelators include deferoxamine, which is administered by injection, and deferasirox and deferiprone, both of which are administered orally. Adherence to iron chelator therapy is an important consideration and may be affected by side effects...
2017: Drugs in Context
https://www.readbyqxmd.com/read/28698121/the-transcriptional-response-of-the-pacific-oyster-crassostrea-gigas-against-acute-heat-stress
#12
Chuanyan Yang, Qiang Gao, Chang Liu, Lingling Wang, Zhi Zhou, Changhao Gong, Anguo Zhang, Huan Zhang, Limei Qiu, Linsheng Song
The Pacific oyster, Crassostrea gigas, has evolved sophisticated mechanisms to adapt the changing ambient conditions, and protect themselves from stress-induced injuries. In the present study, the expression profiles of mRNA transcripts in the haemocytes of oysters under heat stress were examined to reveal the possible mechanism of heat stress response. There were 23,315, 23,904, 23,123 and 23,672 transcripts identified in the haemocytes of oysters cultured at 25 °C for 0, 6, 12, and 24 h (designed as B, H6, H12, H24), respectively...
July 8, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28696095/dt-diaphorase-as-a-bifunctional-enzyme-label-that-allows-rapid-enzymatic-amplification-and-electrochemical-redox-cycling
#13
Cheolho Kang, Juyeon Kang, Nam-Sihk Lee, Young Ho Yoon, Haesik Yang
The most common enzyme labels in enzyme-linked immunosorbent assays are alkaline phosphatase and horseradish peroxidase, which, however, have some limitations for use in electrochemical immunosensors. This Article reports that the small and thermostable DT-diaphorase (DT-D) and electrochemically inactive 4-nitroso-1-naphthol (4-NO-1-N) can be used as a bifunctional enzyme label and a rapidly reacting substrate, respectively, for electrochemical immunosensors. This enzyme-substrate combination allows high signal amplification via rapid enzymatic amplification and electrochemical redox cycling...
July 11, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28692474/molecular-adsorbent-recirculating-system-effectively-replaces-hepatic-function-in-severe-acute-liver-failure
#14
Steven I Hanish, Deborah M Stein, Joseph R Scalea, Eno-Obong Essien, Paul Thurman, William R Hutson, Stephen T Bartlett, Rolf N Barth, Thomas M Scalea
BACKGROUND DATA: Patients with severe acute liver failure (ALF) have extreme physiologic dysfunction and often die if transplantation is not immediately available. Patients may be supported with MARS (Baxter International Inc., Deerfield, IL) until transplantation or spontaneous recovery occurs. We present the largest series in the United States of MARS therapy as temporary hepatic replacement for ALF. METHODS: MARS was used to support patients with severe liver trauma (SLT), in ALF patients as a bridge to transplantation (BTT), and as definitive therapy for toxic ingestion or idiopathic liver failure (DT) in a level 1 trauma center and large transplant center...
July 7, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28685796/tuberculosis-cost-in-tunisia
#15
Mohamed Hsairi, Mehdi Ben Braham, Dhikrayet Gamara, Rachid Fourati, Faouzi Abid, Fatma Tritar, Mohamed Ridha Charfi
BACKGROUND: Tuberculosis (TB) infects one third of the world population. Its economic impact is important, affecting the global economy in the World. OBJECTIVE: To determine the economic costs related to tuberculosis in Tunisia. METHODS: Calculations were made for the reference year 2013; we covered all cost components of the disease, which are related to program management, BCG vaccination, health workers training, social mobilization, screening, chemoprophylaxis, and tuberculosis care...
October 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28684598/reduced-collagen-accumulation-and-augmented-mmp-2-activity-in-left-ventricle-of-old-rats-submitted-to-high-intensity-resistance-training
#16
Vinicius Guzzoni, Rita C Marqueti, João Luiz Quagliotti Durigan, Hernandes F Carvalho, Rafael Lino, Marcelo S Mekaro, Tayná Dos Santos, Andre Souza Mecawi, Jose Antunes-Rodrigues, Jeffrey M Hord, Jonh M Lawler, Ana Paula Davel, Heloísa Sobreiro Selistre-de-Araujo
Progressive fibrosis is a hallmark of the aging heart. Age-related fibrosis is modulated by endurance exercise training; however, little is known concerning the influence of resistance training (RT). Therefore, we investigated the chronic effects of high-intensity RT on age-associated alterations of left ventricle (LV) structure, collagen content, matrix metalloproteinase-2 (MMP-2) and extracellular matrix-related gene expression, including transforming growth factor-β (TGF-β). Young adult (3 mo.) and aged (21 mo...
July 6, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28684273/chicken-dna-virus-sensor-ddx41-activates-ifn-%C3%AE-signaling-pathway-dependent-on-sting
#17
Yuqiang Cheng, Yunxia Liu, Yingying Wang, Qiaona Niu, Quanxin Gao, Qiang Fu, Jingjiao Ma, Hengan Wang, Yaxian Yan, Chan Ding, Jianhe Sun
The recognition of pathogenic DNA is important to the initiation of antiviral responses. Here, we report the identification of the first avian DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (DDX41), an important DNA sensor, in chicken cells. In our study, we confirmed that chDDX41 is not an interferon-inducible gene. Knockdown of chDDX41 expression by shRNA blocked the ability of DF-1 cells to mount an IFN-β response to DNA and associated viruses. ChDDX41 mRNAs could be upregulated by double-stranded DNA (dsDNA) analogue poly(dA:dT), but not by double-stranded RNA (dsRNA) analogue poly(I:C)...
July 3, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28683998/biodegradable-vs-nonbiodegradable-cardiac-support-device-for-treating-ischemic-cardiomyopathy-in-a-canine-heart
#18
Mutsunori Kitahara, Shigeru Miyagawa, Satsuki Fukushima, Atsuhiro Saito, Ayumi Shintani, Toshiaki Akita, Yoshiki Sawa
Clinical studies of the efficacy of the nonbiodegradable CorCap device have shown inconsistent findings, at least in part, because of device-related impairment of diastolic cardiac function. We hypothesized that use of biodegradable material for the cardiac support device could contribute to an improvement in the diastolic function of the failing heart. Polyglycolic acid and polyethylene terephthalate were used to prepare biodegradable and nonbiodegradable cardiac support devices, respectively. Twelve-month-old beagles underwent anterior coronary artery ligation...
April 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28683794/genome-wide-analysis-of-wox-genes-in-upland-cotton-and-their-expression-pattern-under-different-stresses
#19
Zhaoen Yang, Qian Gong, Wenqiang Qin, Zuoren Yang, Yuan Cheng, Lili Lu, Xiaoyang Ge, Chaojun Zhang, Zhixia Wu, Fuguang Li
BACKGROUND: WUSCHEL-related homeobox (WOX) family members play significant roles in plant growth and development, such as in embryo patterning, stem-cell maintenance, and lateral organ formation. The recently published cotton genome sequences allow us to perform comprehensive genome-wide analysis and characterization of WOX genes in cotton. RESULTS: In this study, we identified 21, 20, and 38 WOX genes in Gossypium arboreum (2n = 26, A2), G. raimondii (2n = 26, D5), and G...
July 6, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28683208/short-term-consumption-of-i-ilex-paraguariensis-i-extracts-protects-isolated-hearts-from-ischemia-reperfusion-injury-and-contradicts-exercise-mediated-cardioprotection
#20
Fábio Cahuê, Simone Souza, Camilli Fernanda Martins Santos, Victor Machado, Jose H M Nascimento, Luciane Barcellos, Verônica P Salerno
PURPOSE: Perfusion of hearts with extracts of <i>Ilex paraguariensis</i> (IP/mate) appears to reduce ischemia/reperfusion (I/R) injury. To determine if oral consumption of IP/mate can provide similar cardioprotection, short-term consumption was investigated alone or in association with exercise in rats. METHODS: Animals were grouped into control (C), IP/mate consumption (M), exercise (E) and exercise with mate (E+M). M and E+M groups consumed IP/mate (1g/kg body weight in 1mL water) by gavage...
July 6, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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