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https://www.readbyqxmd.com/read/28318084/twisted-aromatic-frameworks-readily-exfoliable-and-solution-processable-two-dimensional-conjugated-microporous-polymers
#1
A Belen Marco, Diego Cortizo-Lacalle, Iñigo Perez-Miqueo, Giovanni Valenti, Alessandro Boni, Jan Plas, Karol Strutyński, Steven De Feyter, Francesco Paolucci, Mario Montes, Andrei N Khlobystov, Manuel Melle-Franco, Aurelio Mateo-Alonso
Twisted two-dimensional aromatic frameworks have been prepared by overcrowding the nodes with bulky and rigid substituents. The highly distorted aromatic framework with alternating out-of-plane substituents results in diminished interlayer interactions that favor the exfoliation and dispersion of individual layers in organic media.
March 20, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28303239/epidemiology-of-ebola-virus-disease-in-the-western-area-region-of-sierra-leone-2014-2015
#2
Margaret Lamunu, Olushayo Oluseun Olu, James Bangura, Zabulon Yoti, Thomas Takpau Samba, David Kabba Kargbo, Foday Mohamed Dafae, Muhammad Ali Raja, Noah Sempira, Michael Lyazi Ivan, Aarti Sing, Fredson Kurti-George, Negusu Worku, Pamela Mitula, Louisa Ganda, Robert Samupindi, Roland Conteh, Kande-Bure Kamara, Beatrice Muraguri, Michael Kposowa, Joseph Charles, Malimbo Mugaga, Christopher Dye, Anshu Banerjee, Pierre Formenty, Brima Kargbo, Raymond Bruce Aylward
INTRODUCTION: Western Area (WA) of Sierra Leone including the capital, Freetown, experienced an unprecedented outbreak of Ebola from 2014 to 2015. At the onset of the epidemic, there was little information about the epidemiology, transmission dynamics, and risk factors in urban settings as previous outbreaks were limited to rural/semi-rural settings. This study, therefore, aimed to describe the epidemiology of the outbreak and the factors which had most impact on the transmission of the epidemic and whether there were different drivers from those previously described in rural settings...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28298794/anesthetic-implications-in-a-child-with-crouzon-syndrome
#3
Ajeet Kumar, Nitika Goel, Chandni Sinha, Abhishek Singh
Crouzon syndrome (CS) is an autosomal dominant genetic disorder characterized by craniofacial dysostosis. Premature fusion of skull base leads to midfacial hypoplasia, shallow orbit, mandibular prognathism, overcrowding of upper teeth, high-arched palate, and upper airway obstruction. It is important for anesthesiologists managing such patients to recognize and avoid potential airway complications. Here, we present a case of a 10-year-old child with CS posted for ptosis correction surgery. Use of peripheral nerve blocks to cut down opioid requirement, inhalational induction, and maintenance are key aspects in successful management of such cases...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28294011/we-must-not-repeat-the-mistakes-of-mid-staffs
#4
Sir Stephen Moss
These are exceptionally tough times for everyone providing care and treatment across NHS settings. Colleagues on the front line face unprecedented pressure day in, day out, without any respite and often with limited resources. As a nurse it distresses me greatly to see graphic images of older, frail patients waiting for long periods on trolleys in overcrowded emergency departments.
March 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28292765/soil-transmitted-helminthiasis-in-indigenous-groups-a-community-cross-sectional-study-in-the-amazonian-southern-border-region-of-ecuador
#5
Natalia Romero-Sandoval, Claudia Ortiz-Rico, Héctor Javier Sánchez-Pérez, Daniel Valdivieso, Carlos Sandoval, Jacob Pástor, Miguel Martín
BACKGROUND: Rural communities in the Amazonian southern border of Ecuador have benefited from governmental social programmes over the past 9 years, which have addressed, among other things, diseases associated with poverty, such as soil transmitted helminth infections. The aim of this study was to explore the prevalence of geohelminth infection and several factors associated with it in these communities. METHODS: This was a cross sectional study in two indigenous communities of the Amazonian southern border of Ecuador...
March 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28279108/is-streaming-patients-a-good-idea
#6
Mandy Rumley-Buss
To reduce delays in patient care and overcrowding in emergency departments (EDs), suitable patients are often streamed away from the department or to separate areas in the department for specialist care.
March 10, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/28275860/parameters-affecting-length-of-stay-in-a-pediatric-emergency-department-a-retrospective-observational-study
#7
Kevin D Hofer, Rotraud K Saurenmann
Prolonged emergency department (ED) length of stay (LOS) is used as a proxy for ED overcrowding and is associated with adverse outcomes of patients requiring therapy and reduced patient satisfaction. Our aim was to identify and quantify variables which affect ED-LOS. Patients admitted to the pediatric ED of a large regional Swiss hospital during a 1-year period were analyzed for LOS (in minutes). Predictor variables included patient-associated parameters (time of admission and discharge, ED occupancy, triage score, diagnosis, and demographic data) and external factors (weekday, time, and season)...
March 8, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28274646/general-characteristics-and-activity-of-emergency-department-short-stay-units-in-spanish-hospitals
#8
Carles Ferré, Ferran Llopis, Francisco Javier Martín-Sánchez, Gonzalo Sempere, Pere Llorens, Carmen Navarro, Mikel Martínez-Ortiz, Antoni Juan
BACKGROUND: Emergency Department (ED) overcrowding mainly due to the lack of access to inpatient beds negatively affects safety and quality of care. Implementation of ED short-stay units (EDSSUs) may help to mitigate this situation. OBJECTIVES: To describe the general characteristics and evaluate the activity of EDSSUs in Spanish hospitals. METHODS: This is a cross-sectional study. A questionnaire was sent to coordinators responsible for the EDSSUs identified among Spanish hospitals appearing on the Ministry of Health Web page...
March 5, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28270154/pandemics-pathogenicity-and-changing-molecular-epidemiology-of-cholera-in-the-era-of-global-warming
#9
REVIEW
Fazle Rabbi Chowdhury, Zannatun Nur, Nazia Hassan, Lorenz von Seidlein, Susanna Dunachie
BACKGROUND: Vibrio cholerae, a Gram-negative, non-spore forming curved rod is found in diverse aquatic ecosystems around the planet. It is classified according to its major surface antigen into around 206 serogroups, of which O1 and O139 cause epidemic cholera. A recent spatial modelling technique estimated that around 2.86 million cholera cases occur globally every year, and of them approximately 95,000 die. About 1.3 billion people are currently at risk of infection from cholera. Meta-analysis and mathematical modelling have demonstrated that due to global warming the burden of vector-borne diseases like malaria, leishmaniasis, meningococcal meningitis, viral encephalitis, dengue and chikungunya will increase in the coming years in the tropics and beyond...
March 7, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28265341/diabetic-ketoacidosis-treatment-in-the-intensive-care-unit-or-general-medical-surgical-ward
#10
EDITORIAL
Yamely Mendez, Salim Surani, Joseph Varon
Diabetic ketoacidosis (DKA) is defined as an acute metabolic disorder, which is characterized by an increased presence of circulating ketones, and the development of ketoacidosis in the presence of hyperglycemia. This syndrome occurs as a result of insulin deficiency. Patients can be dramatically ill, however, with aggressive treatment, most patients recover rapidly. Despite being a low-risk condition, the development of acidosis, is one of the admission criteria to the intensive care unit (ICU) for these patients, in order to provide close monitoring, and recognize complications that could result from the use of aggressive therapy, such as continuous infusions if insulin...
February 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28250940/a-heuristic-approach-to-evaluate-peri-interactions-versus-intermolecular-interactions-in-an-overcrowded-naphthalene
#11
Sounak Sarkar, Tayur N Guru Row
Octachloronaphthalene (OCN), a serious environmental pollutant, has been investigated by charge density analysis to unravel several unexplored factors responsible for steric overcrowding. The topological features of the enigmatic peri interactions contributing to steric overcrowding are qualified and quantified from experimental and theoretical charge-density studies. A new facet in the fundamental understanding of peri interactions is revealed by NCI (non-covalent interaction) analysis. The potential role of these interactions in deforming the molecular geometry and subsequent effect on aromaticity are substantiated from NICS (Nuclear Independent Chemical Shift) and QTAIM (Quantum Theory of Atoms in Molecules) calculations...
January 1, 2017: IUCrJ
https://www.readbyqxmd.com/read/28246211/apoptosis-restores-cellular-density-by-eliminating-a-physiologically-or-genetically-induced-excess-of-enterocytes-in-the-drosophila-midgut
#12
Rihab Loudhaief, Alexandra Brun-Barale, Olivia Benguettat, Marie-Paule Nawrot-Esposito, David Pauron, Marcel Amichot, Armel Gallet
Using pathogens or high levels of opportunistic bacteria to damage the gut, studies in Drosophila have identified many signaling pathways involved in gut regeneration. Dying cells emit signaling molecules that accelerate intestinal stem cell proliferation and progenitor differentiation to replace the dying cells quickly. This process has been named 'regenerative cell death'. Here, mimicking environmental conditions, we show that the ingestion of low levels of opportunistic bacteria was sufficient to launch an accelerated cellular renewal program despite the brief passage of bacteria in the gut and the absence of cell death and this is is due to the moderate induction of the JNK pathway that stimulates stem cell proliferation...
March 1, 2017: Development
https://www.readbyqxmd.com/read/28241931/text-mining-approach-to-predict-hospital-admissions-using-early-medical-records-from-the-emergency-department
#13
Filipe R Lucini, Flavio S Fogliatto, Giovani J C da Silveira, Jeruza L Neyeloff, Michel J Anzanello, Ricardo de S Kuchenbecker, Beatriz D Schaan
OBJECTIVE: Emergency department (ED) overcrowding is a serious issue for hospitals. Early information on short-term inward bed demand from patients receiving care at the ED may reduce the overcrowding problem, and optimize the use of hospital resources. In this study, we use text mining methods to process data from early ED patient records using the SOAP framework, and predict future hospitalizations and discharges. DESIGN: We try different approaches for pre-processing of text records and to predict hospitalization...
April 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28230800/mutilating-procedures-management-practices-and-housing-conditions-that-may-affect-the-welfare-of-farm-animals-implications-for-welfare-research
#14
Rebecca E Nordquist, Franz Josef van der Staay, Frank J C M van Eerdenburg, Francisca C Velkers, Lisa Fijn, Saskia S Arndt
A number of mutilating procedures, such as dehorning in cattle and goats and beak trimming in laying hens, are common in farm animal husbandry systems in an attempt to prevent or solve problems, such as injuries from horns or feather pecking. These procedures and other practices, such as early maternal separation, overcrowding, and barren housing conditions, raise concerns about animal welfare. Efforts to ensure or improve animal welfare involve adapting the animal to its environment, i.e., by selective breeding (e...
February 21, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28228344/emergency-department-return-visits-within-a-large-geographic-area
#15
Mimi Truong, Garth Meckler, Quynh H Doan
BACKGROUND: Return visits to the emergency department (RTED) contribute to overcrowding and may be a quality of care indicator. Previous studies focused on factors predicting returns to and from the same center. Little is known about RTEDs across a range of community and specialty hospitals within a large geographic area. OBJECTIVE: We sought to measure the frequency of pediatric RTEDs and describe their directional pattern across centers in a large catchment area...
February 19, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28222109/ppd-induced-monocyte-mitochondrial-damage-is-associated-with-a-protective-effect-to-develop-tuberculosis-in-bcg-vaccinated-individuals-a-cohort-study
#16
Diana Marín, Nancy Marín, Helena Del Corral, Lucelly López, María Elena Ramirez-Agudelo, Carlos A Rojas, María P Arbeláez, Luis F García, Mauricio Rojas
INTRODUCTION: The mechanisms of mononuclear phagocyte death have been associated with the permissiveness and resistance to mycobacterial replication, but it remains unknown whether or not they help predict the risk of developing TB. OBJECTIVE: To describe the factors associated with the induction of monocyte mitochondrial and membrane damage in response to PPD as well as determine if this type of damage might predict the susceptibility of developing active tuberculosis in a cohort of household contacts (HHCs) from Medellin, Colombia from 2005 to 2008...
2017: PloS One
https://www.readbyqxmd.com/read/28208351/effects-of-burstiness-on-the-air-transportation-system
#17
Hidetaka Ito, Katsuhiro Nishinari
The effects of burstiness in complex networks have received considerable attention. In particular, the effects on temporal distance and delays in the air transportation system are significant owing to their huge impact on our society. Therefore, in this paper, the temporal distance of empirical U.S. flight schedule data is compared with that of regularized data without burstiness to analyze the effects of burstiness. The temporal distance is calculated by a graph analysis method considering flight delays, missed connections, flight cancellations, and congestion...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28207783/patient-experience-with-outpatient-encounters-at-public-hospitals-in-shanghai-examining-different-aspects-of-physician-services-and-implications-of-overcrowding
#18
Yuhua Bao, Guanrong Fan, Dongdong Zou, Tong Wang, Di Xue
BACKGROUND: Over 90% of outpatient care in China was delivered at public hospitals, making outpatient experience in this setting an important aspect of quality of care. OBJECTIVE: To assess outpatient experience with different aspects of physician services at China's public hospitals and its association with overcrowding of the hospital outpatient departments. RESEARCH DESIGN: Retrospective analysis of a large survey of outpatient experience in Shanghai, China...
2017: PloS One
https://www.readbyqxmd.com/read/28207411/reporting-altered-test-results-in-hemolyzed-samples-is-the-cure-worse-than-the-disease
#19
Giuseppe Lippi, Gianfranco Cervellin, Mario Plebani
The management of laboratory data in unsuitable (hemolyzed) samples remains an almost unresolved dilemma. Whether or not laboratory test results obtained by measuring unsuitable specimens should be made available to the clinicians has been the matter of fierce debates over the past decades. Recently, an intriguing alternative to suppressing test results and recollecting the specimen has been put forward, entailing the definition and implementation of specific algorithms that would finally allow reporting a preanalytically altered laboratory value within a specific comment about its uncertainty of measurement...
February 16, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28183038/supplementary-feeding-and-endoparasites-in-threatened-avian-scavengers-coprologic-evidence-from-red-kites-in-their-wintering-stronghold
#20
Guillermo Blanco, Jesús Cardells, María M Garijo-Toledo
Many obligate and facultative avian scavengers are increasingly dependent on food provided in supplementary feeding stations (SFS), which are managed for the conservation of these species. Deliberate feeding can influence disease-related host demography and population dynamics through physiological changes and density-dependent parasite acquisition and transmission, but information on this threat to avian scavengers is scarce. Due to their effects on host aggregation and density, we hypothesised that the predictability and concentration of food in SFS can exacerbate parasite infection...
May 2017: Environmental Research
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