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https://www.readbyqxmd.com/read/28326216/an-unusual-clinical-presentation-of-solitary-fibrous-tumor-in-the-oral-cavity
#1
Everton Freitas de Morais, Deborah Gondim Lambert Moreira, Viviane Alves De Oliveira, Rodrigo Rodrigues Rodrigues, Adriano Rocha Germano, Roseana de Almeida Freitas
Solitary fibrous tumor is a rare neoplasm of mesenchymal origin that usually affects the pleura. This rarity becomes more relevant in the oral cavity since the clinical features are nonspecific. A 66-year-old female patient presented with a 3-month history of a swelling in the floor of the mouth, measuring 2 cm in greatest diameter, and pain symptomatology. Occlusal and panoramic radiographs showed no bone involvement. Ultrasonography of the submandibular and parotid salivary glands revealed normal morphology, dimensions, and echogenicity...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28318166/-exploratory-study-on-influence-of-biopsy-to-biological-behavior-of-tca8113-transplanted-tumor
#2
Liu Jiyuan, Pan Jian, Hua Chengge, Wu Yunlong, Luo Zhengwen, Tang Xiufa
OBJECTIVE: We established an animal model of nude mice with Tca8113 tumor and cut some tissue for biopsy. We also determined the biological behavior and mechanisms of the tumor. METHODS: The mice were divided into two groups randomly. Mice in both groups were injected with Tca8113 cells into their tongues. The survival condition, growth of primary focus, and metastasis were observed. Hematoxylin and eosin staining and immunohistochemistry were performed on nuclear factor κB (NF-κB), matrix metallopeptidase 9 (MMP-9), vascular endothelial growth factor (VEGF), stromal cell-derived factor 1 (SDF-1), and Ki67 to determine their distributions within the tumor...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28317830/-experience-of-organ-spare-sialolitiasis-treatment-using-sialoendoscopy
#3
V N Balin, S Yu Zolotukhin
The aim of the study was to evaluate the effectiveness of organ spare sialolitiasis treatment by sialoscopy-guided techniques. The study included 317 patients with parotid and submandibular sialolitiasis. In 22 patients conventional surgical approach was used because of distal location and larger size of concrements, while in 295 miniinvasive sialoscopy-guided procedures were performed. The use of sialoscopy-guided approach drastically diminished the rate of submandibular glands extirpations (performed in 5% of patients), as well as early and long-term surgical complications...
2017: Stomatologii︠a︡
https://www.readbyqxmd.com/read/28315910/effect-of-selenium-supplementation-for-protection-of-salivary-glands-from-iodine-131-radiation-damage-in-patients-with-differentiated-thyroid-cancer
#4
Haiyoung Son, Sang Mi Lee, Ra Gyoung Yoon, Hakmin Lee, Ilkyun Lee, Soon Kim, Woong Youn Chung, Jeong Won Lee
OBJECTIVE: In the current study, we examined whether selenium supplementation during iodine-131 ((131)I) treatment had a radio-protective effect on salivary glands. SUBJECTS AND METHODS: Sixteen patients with differentiated thyroid cancer were prospectively enrolled in the study. Patients after total thyroidectomy, before (131)I treatment, were divided into two groups; 8 patients in the selenium group and 8 patients in the control group. Patients in the selenium group received 300νg of selenium orally for 10 days, from 3 days before to 6 days after (131)I treatment...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28304087/feasibility-of-endoscopic-submandibular-ganglion-neurectomy-for-drooling
#5
Kayhan Ozturk, Omer Erdur, Osman Gul, Ayse Olmez
We performed endoscopic transoral neurectomy of the submandibular and sublingual glands to treat drooling. We bilaterally operated two adult cases with treatment-resistant drooling. In these patients, conventional treatment had failed. Repeated botilinum toxin type A (BOTOX®, Abdi Ibrahim Pharmaceutical Company, Istanbul, Turkey) injections had been effective but were becoming less so. The patients benefited from surgery in that their saliva scores decreased. No issue emerged over 6 months of follow-up. Endoscopic transoral neurectomy of the submandibular and sublingual glands reduces saliva production and allows management of drooling in treatment-resistant patients...
March 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28299899/salivary-gland-hypofunction-in-kk-ay-type-2-diabetic-mice
#6
Takashi Munemasa, Taro Mukaibo, Yusuke Kondo, Chihiro Masaki, Yuichiro Kusuda, Yuta Miyagi, Shintaro Tsuka, Ryuji Hosokawa, Tetsuji Nakamoto
BACKGROUND: Diabetes mellitus induces several hypofunctions in the body, including in the oral cavity. It is often associated with xerostomia, however the detailed underlying mechanism is not well characterized. METHODS: We used KK-Ay mice, a model of type 2 diabetes, to analyze the mechanism of diabetes-induced xerostomia with the ex vivo glandular perfusion technique, histological analysis, immunohistochemically and intracellular signaling analysis. RESULTS: Ex vivo submandibular gland secretions from KK-Ay mice decreased by 30% when stimulated with moderate stimulation of cholinergic agonist 0...
March 16, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28298895/two-phase-modulation-of-formula-see-text-entry-and-cl-formula-see-text-exchanger-in-submandibular-glands-cells-by-dexmedetomidine
#7
Minjeong Ji, Chul-Kyu Park, Jin Woo Lee, Kook Yang Park, Kuk Hui Son, Jeong Hee Hong
Dexmedetomidine (Dex), a highly selective α2-adrenoceptor agonist, attenuates inflammatory responses induced by lipopolysaccharide (LPS) and induces sedative and analgesic effects. Administration of Dex also reduces salivary secretion in human subjects and inhibits osmotic water permeability in rat cortical collecting ducts. However, little is known about the mechanisms underlying the effects of Dex on salivary glands fluid secretion. We demonstrated the α2-adrenoceptor expression in the basolateral membrane of mouse submandibular glands (SMG)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28296017/application-of-ultrasound-guided-pigtail-catheter-drainage-for-abscesses-in-the-head-and-neck
#8
Byung Yoon Joo, Ae Lan Jang, Joon Hyung Lee, Heon Soo Park, Myung Koo Kang, Jong Chul Hong
Abscesses in the head and neck are relatively common diseases with varied symptoms and severities. These abscesses are usually caused by upper respiratory infections, trauma, foreign bodies, postoperative infections, malignancies or dental infections.(1,2) The regions where abscesses can develop in the head and neck, include fascial planes and potential spaces such as submandibular, sublingual, submental, parapharyngeal, retropharyngeal, pretracheal, masticator or infratemporal areas.(3) This article is protected by copyright...
March 10, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28289635/accuracy-of-ultrasound-guided-and-non-ultrasound-guided-botulinum-toxin-injection-into-cadaver-salivary-glands
#9
Jae In So, Dae Heon Song, Joo Hyun Park, Eunseok Choi, Jung Yoon Yoon, Yeonji Yoo, Myung Eun Chung
OBJECTIVE: To compare the accuracy of ultrasound (US)-guided and non-US-guided botulinum toxin (BTX) injection into the salivary glands (parotid and submandibular glands) of cadavers. METHODS: Two rehabilitation physician injected dye into three sites in the salivary glands (two sites in the parotid gland and one site in the submandibular gland) on one side of each cadaver (one was injected on the right side, while the other was injected on the left side), using either a non-US-guided injection procedure based on superficial landmarks or a US-guided procedure...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28284020/frenotomy-for-tongue-tie-in-newborn-infants
#10
REVIEW
Joyce E O'Shea, Jann P Foster, Colm Pf O'Donnell, Deirdre Breathnach, Susan E Jacobs, David A Todd, Peter G Davis
BACKGROUND: Tongue-tie, or ankyloglossia, is a condition whereby the lingual frenulum attaches near the tip of the tongue and may be short, tight and thick. Tongue-tie is present in 4% to 11% of newborns. Tongue-tie has been cited as a cause of poor breastfeeding and maternal nipple pain. Frenotomy, which is commonly performed, may correct the restriction to tongue movement and allow more effective breastfeeding with less maternal nipple pain. OBJECTIVES: To determine whether frenotomy is safe and effective in improving ability to feed orally among infants younger than three months of age with tongue-tie (and problems feeding)...
March 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28282518/a-case-of-nuclear-protein-in-testis-midline-carcinoma-arising-from-the-submandibular-gland-duct-in-a-pregnant-patient
#11
Younghoon Cho, Bhum Suk Keam, Kyeong Cheon Jung, Kim Bo Hae
This report describes the first reported case of a nuclear protein in testis midline carcinoma (NMC) arising from the submandibular gland (SMG) duct in a pregnant woman. A 29-year-old pregnant woman presented with a left-side mass in the floor of the mouth. An NMC arising from the SMG duct was confirmed by excisional biopsy examination. Intensive treatment, including surgery and chemotherapy, was provided without termination of the pregnancy. Additional chemotherapy and radiotherapy were provided after delivery...
February 14, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28277296/botox-a-injection-of-salivary-glands-for-drooling
#12
Ana Alvarenga, Miguel Campos, Mariana Dias, Lina Melão, José Estevão-Costa
BACKGROUND AND PURPOSE: Drooling is a challenging entity to manage. Botulinum toxin A (BOTOX-A) infiltration of salivary glands is a promising alternative to surgical treatment. This study aims to assess the outcome of BOTOX-A salivary glands infiltration in children with drooling. METHODS: Patients treated between January 2012 and March 2015 were enrolled. BOTOX-A was injected in the parotid and submandibular glands under ultrasound control and general inhalational anesthesia...
October 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28273355/evaluation-of-segmentation-methods-on-head-and-neck-ct-auto-segmentation-challenge-2015
#13
Patrik F Raudaschl, Paolo Zaffino, Gregory C Sharp, Maria Francesca Spadea, Antong Chen, Benoit M Dawant, Thomas Albrecht, Tobias Gass, Christoph Langguth, Marcel Lüthi, Florian Jung, Oliver Knapp, Stefan Wesarg, Richard Mannion-Haworth, Mike Bowes, Annaliese Ashman, Gwenael Guillard, Alan Brett, Graham Vincent, Mauricio Orbes-Arteaga, David Cárdenas-Peña, German Castellanos-Dominguez, Nava Aghdasi, Yangming Li, Angelique Berens, Kris Moe, Blake Hannaford, Rainer Schubert, Karl D Fritscher
PURPOSE: Automated delineation of structures and organs is a key step in medical imaging. However, due to the large number and diversity of structures and the large variety of segmentation algorithms a consensus is lacking as to which automated segmentation method works best for certain applications. Segmentation challenges are a good approach for unbiased evaluation and comparison of segmentation algorithms. METHODS: In this work we describe and present the results of the Head and Neck Auto-Segmentation Challenge 2015, a satellite event at the Medical Image Computing and Computer Assisted Interventions (MICCAI) 2015 conference...
March 8, 2017: Medical Physics
https://www.readbyqxmd.com/read/28271999/postoperative-radiotherapy-in-salivary-gland-carcinoma-a-single-institution-experience
#14
Öztun Temelli, Ersoy Kekilli, Ahmet Kizilay
BACKGROUND: Salivary gland carcinoma are rare tumors and the main treatment is surgical. The addition of radiotherapy to surgery decreases locoregional relapses in high risk patients. Aim of our study is to retrospectively evaluate local control and survival and the factors affecting them in patients who received postoperative radiotherapy. MATERIALS AND METHODS: The medical records of 30 patients with salivary gland tumors operated on and referred to our clinic for adjuvant RT between January 2004 and June 2015 were retrospectively evaluated...
January 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28270226/first-in-man-mesenchymal-stem-cells-for-radiation-induced-xerostomia-mesrix-study-protocol-for-a-randomized-controlled-trial
#15
Christian Grønhøj, David H Jensen, Peter V Glovinski, Siri Beier Jensen, Allan Bardow, Roberto S Oliveri, Lena Specht, Carsten Thomsen, Sune Darkner, Katalin Kiss, Anne Fischer-Nielsen, Christian von Buchwald
BACKGROUND: Salivary gland hypofunction and xerostomia are major complications following radiotherapy for head and neck cancer and may lead to debilitating oral disorders and impaired quality of life. Currently, only symptomatic treatment is available. However, mesenchymal stem cell (MSC) therapy has shown promising results in preclinical studies. Objectives are to assess safety and efficacy in a first-in-man trial on adipose-derived MSC therapy (ASC) for radiation-induced xerostomia...
March 7, 2017: Trials
https://www.readbyqxmd.com/read/28264651/interactions-of-histatin-3-and-histatin-5-with-actin
#16
Edna Blotnick, Asaf Sol, Gilad Bachrach, Andras Muhlrad
BACKGROUND: Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and -5 are the most important polycationic histatins. They possess antimicrobial activity against fungi such as Candida albicans. Histatin-5 has a higher antifungal activity than histatin-3 while histatin-3 is mostly involved in wound healing in the oral cavity. We found that these histatins, like other polycationic peptides and proteins, such as LL-37, lysozyme and histones, interact with extracellular actin...
March 6, 2017: BMC Biochemistry
https://www.readbyqxmd.com/read/28264544/efficacy-of-bont-a-and-swallowing-treatment-for-oropharyngeal-dysphagia-recovery-in-a-patient-with-lateral-medullary-syndrome-a-case-study
#17
Irene Battel, Isabella Koch, Federica Biddau, Carla Carollo, Francesco Piccione, Francesca Meneghello, Merico Antonio, Katie Palmer, Rosario Marchese Ragona
BACKGROUND: Wallenberg's syndrome (WS) is known as posterior inferior cerebellar artery syndrome. Dysphagia has been reported from 51% to 94% of the patients, ranging from mild to severe. CASE PRESENTATION: We reported a case of a patient (Male; 52yrs) with WS. MRI showed an intense hypodense area in the dorsolateral part of the ponto-medullary junction. The clinical signs were severe dysphagia, fed by PEG (FOIS 1; PAS 7), sialorrhea, trismus and ataxia. CLINICAL REHABILITATION IMPACT: Dysphagia was treated by botulinum toxin tipe A (BoNT-A), which was injected into the parotid and submandibular salivary glands, temporalis and masseter muscles, cricopharyngeal muscle associated with specific swallowing exercise and food trails...
March 6, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28260286/-the-quantitative-evaluation-of-early-radiation-induced-changes-in-the-salivary-glands-using-mri
#18
S Zhou, J J Qian, L Xu, Y Tian, Q H Fan, J K Shen, G H Fan, J P Gong, M H Qian
Objective: To quantitatively evaluate the early radiation injury of salivary glands in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT). Methods: Twenty patients with NPC between 2014 and 2015 from the Second Affiliated Hospital of Soochow University were retrospectively analyzed.All patients underwent an MRI scan before and after IMRT.The volumes, T(1)WI, T(2)WI signal intensity(SIs) and apparent diffusion coefficient (ADCs) of the parotid and submandibular glands were measured...
February 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28258315/impact-of-low-level-laser-therapy-on-hyposalivation-salivary-ph-and-quality-of-life-in-head-and-neck-cancer-patients-post-radiotherapy
#19
Luiz Felipe Palma, Fernanda Aurora Stabile Gonnelli, Marcelo Marcucci, Rodrigo Souza Dias, Adelmo José Giordani, Roberto Araújo Segreto, Helena Regina Comodo Segreto
Late effects of radiotherapy for head and neck cancer treatment have been increasingly investigated due to its impact on patients' quality of life. The purpose of this study was to evaluate the effect of low-level laser therapy on hyposalivation, low salivary pH, and quality of life in head and neck cancer patients post-radiotherapy. Twenty-nine patients with radiation-induced xerostomia received laser sessions twice a week, during 3 months (24 sessions). For this, a continuous wave Indium-Gallium-Aluminium-Phosphorus diode laser device was used punctually on the major salivary glands (808 nm, 0...
March 3, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28254238/corrigendum-to-hidden-scar-submandibular-gland-excision-using-an-endoscope-assisted-hairline-approach-oral-oncol-65-2017-83-88
#20
Seung Hoon Woo, Jung Je Park, MinSu Kwon, Jin Pyeong Kim
No abstract text is available yet for this article.
February 18, 2017: Oral Oncology
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