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https://www.readbyqxmd.com/read/29244890/prevalence-and-predictors-of-sj%C3%A3-gren-s-syndrome-in-patients-with-burning-mouth-symptoms
#1
Young Chan Lee, Ran Song, You-Jung Yang, Young-Gyu Eun
AIMS: To investigate the prevalence and predictive factors of Sjögren's syndrome (SS) in a cohort of patients with burning mouth symptoms. METHODS: A total of 125 patients with burning mouth symptoms were enrolled in a prospective study and assessed for the presence of SS. The severity of oral symptoms was evaluated by using questionnaires. Salivary flow rates and salivary scintigraphy were used to evaluate salivary function. Patient laboratory work-ups were reviewed, and SS was diagnosed by a rheumatologist based on the American-European Consensus Group criteria...
December 15, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29243095/ca2-camkk%C3%AE-pathway-is-required-for-adiponectin-induced-secretion-in-rat-submandibular-gland
#2
Chong Ding, Zhi-Hao Du, Sheng-Lin Li, Li-Ling Wu, Guang-Yan Yu
Adiponectin functions as a promoter of saliva secretion in rat submandibular gland via activation of adenosine monophosphate-activated protein kinase (AMPK) and increased paracellular permeability. Ca2+ mobilization is the primary signal for fluid secretion in salivary acinar cells. However, whether intracellular Ca2+ mobilization is involved in adiponectin-induced salivary secretion is unknown. Here, we found that full-length adiponectin (fAd) increased intracellular Ca2+ and saliva secretion in submandibular glands...
December 14, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/29239938/latest-advances-in-ultrasound-assessment-of-salivary-glands-in-sj%C3%A3-gren-syndrome
#3
María Victoria Martire, María Lida Santiago, Tomas Cazenave, Marwin Gutierrez
OBJECTIVE: There are different imaging techniques to assess the parotid glands (i.e., sialography, salivary gland scintigraphy) in patients with Sjögren syndrome (SS). However, their use is limited by the invasive character or high cost. Ultrasound (US) is gaining interest by rheumatologists as a complementary diagnostic tool for SS. To date, there is an increasing body of evidence supporting its sensitivity in the assessment of salivary glands in SS. The aim of our study was to analyze the potential role of US as a diagnostic and prognostic tool in SS and to discuss existing evidence to support its application use...
December 12, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29237527/-a-rhabdomyosarcoma-patient-from-a-li-fraumeni-syndrome-family-a-case-report-and-literature-review
#4
Yao Xie, Wei-Hong Zhao, Ying Hua, Qing Sun, Peng-Hui Wu
Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome, with the characteristics of early onset of cancer and high cancer incidence. TP53 is widely accepted as a pathogenic gene of LFS. A 2 years and 6 months old boy is reported in this article, who was diagnosed with embryonal rhabdomyosarcoma (RMS) in the left submandibular region. His brother died of RMS, and his grandmother was diagnosed with breast cancer. TP53 gene mutation detection was performed in this patient and some family members, indicating a missense mutation in exon 8 of the patient: c...
December 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29236363/diabetic-status-influences-the-storage-of-melatonin-in-human-salivary-glands
#5
Michela Isola, Maria Alberta Lilliu, Francesco Loy, Raffaella Isola
Recently we reported on the detailed localization of melatonin (and its receptors) in human salivary glands, revealing that serous cells are able to store and secrete melatonin into saliva. Since we found that type 2 diabetic patients display reduced melatonin content in saliva, our next step was to examine the presence of melatonin in salivary glands removed from type 2 diabetic subjects. The resulting data were compared with those previously obtained by identical procedures in non diabetics, to establish if the diabetic status may affect melatonin distribution...
December 13, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29233833/scoring-hypoechogenic-areas-in-one-parotid-and-one-submandibular-gland-increases-feasibility-of-ultrasound-in-primary-sj%C3%A3-gren-s-syndrome
#6
Esther Mossel, Suzanne Arends, Jolien F van Nimwegen, Konstantina Delli, Alja J Stel, Frans G M Kroese, Fred K L Spijkervet, Arjan Vissink, Hendrika Bootsma
OBJECTIVE: To assess whether ultrasonographic scoring of (i) both parotid and submandibular salivary glands and (ii) all individual components of the Hocevar scoring system, is needed for classifying patients as primary Sjögren's syndrome (pSS). METHODS: Ultrasound examination of the major salivary glands (sUS) was performed in 204 consecutive patients clinically suspected (n=171) or diagnosed (n=33) with pSS.Parenchymal echogenicity, homogeneity, hypoechogenic areas, hyperechogenic reflections and salivary gland posterior border were scored in left and right parotid and submandibular glands...
December 12, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29231259/pernio-as-the-presenting-sign-of-blast-crisis-in-acute-lymphoblastic-leukemia
#7
Kelly K Park, Bailey Tayebi, Lily Uihlein, Jodi Speiser, Adnan Mir, Pedram Gerami, Anthony Mancini, Wendy Kim
A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio...
December 12, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29231036/mucoepidermoid-carcinoma-mimicking-a-mucocele-ranula-in-the-floor-of-the-mouth
#8
Saulo L Sousa Melo, Emily Lanzel, Nitin A Pagedar, Daniah Alhazmi, Laila Dahmoush, Bruno A Policeni, Marcia S Campos
Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The submandibular gland is rarely involved, about less than 10% of all other major salivary glands. We report a case of a 49 year-old female who presented with a mass on the left side of the floor of the mouth. She was complaining of neck pain for the last 2-3 days and had noticed the mass growing in size and becoming tender to palpation. There was no exacerbation of pain during eating, drinking or opening of mouth. A multidetector computed tomography scan was made...
December 12, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29227792/nodal-stage-is-it-a-prognostic-factor-for-submandibular-gland-cancer
#9
Yanbin Liu, Lizheng Qin, RunTao Zhuang, Xin Huang, Ming Su, Zhengxue Han
PURPOSE: Submandibular gland cancer is relatively rare. The purpose of this study was to estimate 5-year overall survival (OS) and disease-free survival (DFS) and to identify prognostic factors associated with OS and DFS for submandibular cancer. MATERIALS AND METHODS: The authors implemented a retrospective cohort study and enrolled a sample of patients with submandibular gland cancer. The predictor variables were age, gender, tumor stage, nodal stage, margin status, and extracapsular spread...
November 21, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29225986/intranodal-palisaded-myofibroblastoma-in-a-submandibular-lymph-node
#10
Leila Bouhajja, Raja Jouini, Olfa Khayat, Wafa Koubâa, Chiraz Mbarek, Ehsen Ben Brahim, Achraf Chedly-Debbiche
Intranodal palisaded myofibroblastoma (IPM), also known as "intranodal hemorrhagic spindle cell tumor with amianthoid fibers," is a rare benign mesenchymal tumor originating from smooth muscle cells and myofibroblasts, often with the presence of amianthoid fibers. Usually IPM affects inguinal lymph nodes, but three cases have been described in the submandibular and cervical lymph nodes. We report a new case of a 44-year-old women with submandibular mass. Cervical ultrasound showed a suspect right submandibular adenomegaly...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29224806/oncogenic-dna-viruses-found-in-salivary-gland-tumors
#11
Alyce A Chen, Tarik Gheit, Marco Stellin, Valentina Lupato, Giacomo Spinato, Roberto Fuson, Anna Menegaldo, Sandrine Mckay-Chopin, Elisa Dal Cin, Giancarlo Tirelli, Maria Cristina Da Mosto, Massimo Tommasino, Paolo Boscolo-Rizzo
BACKGROUND: Previous investigations studying the association of DNA viruses with salivary gland tumors (SGTs) have led to conflicting results. The aim of this study was to determine the prevalence of different DNA viruses by using a highly sensitive assay in a multi-center series of over 100 fresh frozen salivary gland samples. METHODS: DNA was isolated from 84 SGTs (80 parotid tumors and 4 submandibular gland tumors) and 28 normal salivary tissue samples from 85 patients in Northeast Italy...
December 2017: Oral Oncology
https://www.readbyqxmd.com/read/29223310/cystinuria-one-possible-reason-for-kidney-and-salivary-gland-lithiasis-relationship
#12
Marc-Kevin Le Roux, Nicolas Graillon, Jean-Marc Foletti, Cyrille Chossegros
Salivary gland lithiasis affects 1 to 2% of adults. The submandibular glands are concerned in 87% of cases. An association between kidney and salivary lithiases, although often mentioned, has rarely been observed. We relate an exceptional case of parotid and submandibular cystine sialolithiasis with kidney cystine lithiasis in a patient with cystinuria. Cystine lithiasis occurs in 1% of kidney lithiasis cases. The purpose of this article is to discuss the arguments, diagnosis, and therapeutic attitude in front of salivary cystine lithiasis...
November 22, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29219039/morphogenesis-and-mucus-production-of-epithelial-tissues-of-three-major-salivary-glands-of-embryonic-mouse-in-3d-culture
#13
Azusa Nakao, Takumi Inaba, Akiko Murakami-Sekimata, Hiroyuki Nogawa
Embryonic mouse submandibular epithelia initiate branching morphogenesis within two days when embedded in Matrigel and stimulated by members of the epidermal growth factor family. However, it is unknown whether the end buds further branch over longer culture periods, and whether saliva-producing cells differentiate there. In the present study, we cultivated three major (submandibular, sublingual and parotid) salivary epithelia from 13-day embryos for 14 days in mesenchyme-free cultures. All epithelia continued to grow and branch to form numerous acinus-like structures in medium supplemented with neuregulin 1, fibroblast growth factor 1, and insulintransferrin-sodium selenite...
December 2017: Zoological Science
https://www.readbyqxmd.com/read/29208942/endoscope-assisted-resection-of-nonneoplastic-space-occupying-lesion-in-oral-and-maxillofacial-areas
#14
Yanan Li, Runqi Xue, Qingguo Lai, Bingbing Xu, Kuifeng Yuan, Xiaopeng Tang, Jiangbo Ci, Shaolong Sun, Zhichao Zhang
Endoscope-assisted oral and maxillofacial surgeries have been applied to the resection of tumors with minimal invasion and good cosmetic outcomes. However, with regard to endoscope-assisted resection of nonneoplastic space-occupying lesion (NSOL) in oral and maxillofacial areas which differ from tumors in treatment, there are no systematic reports. Therefore the advantages and limitations of the endoscopy-assisted approach (EAA) in resection of NSOL remain unclear. In this novel study we describe endoscope technique for resection of NSOL in face and submandibular areas and compare the feasibility and effectiveness of EAA with external approach (EA)...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29204918/sialendoscopy-in-treating-pediatric-salivary-gland-disorders-a-systematic-review
#15
REVIEW
Yehuda Schwarz, Aren Bezdjian, Sam J Daniel
OBJECTIVE: The primary aim of this study is to conduct a systematic review in order to evaluate the use of sialendoscopy in treating pediatric salivary gland disorders. METHODS: Eligible articles were identified through a comprehensive search of electronic databases. Using predefined inclusion criteria, published articles on sialendoscopy in children were selected and reviewed. RESULTS: 17 articles including 323 pediatric patients and 424 salivary glands managed by sialendoscopy were identified...
December 4, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29203744/differences-in-clinical-manifestations-of-odontogenic-and-non-odontogenic-lymphadenitis
#16
Pavlo I Tkachenko, Viitalina O Dobroskok, Nataliia M Korotych, Inna A Kolisnyk
INTRODUCTION: The acute suppurative lymphadenitis and its chronic forms prevail in the structure of inflammatory processes of the maxillofacial area in children. High incidence of the acute and chronic forms of lymphadenitis of both odontogenic and nonodontogenic origin is caused by the anotomophysiological peculiarities of the structure of the teeth and soft tissues in children in different age periods. THE AIM: The paper was aimed at comparison of clinical manifestations of the acute and chronic odontogenic and non-odontogenic lymphadenitis...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29203260/the-helsinki-face-transplantation-surgical-aspects-and-1-year-outcome
#17
Patrik Lassus, Andrew Lindford, Jyrki Vuola, Leif Bäck, Sinikka Suominen, Karri Mesimäki, Tommy Wilkman, Tuija Ylä-Kotola, Erkki Tukiainen, Hannu Kuokkanen, Jyrki Törnwall
BACKGROUND: Since 2005, at least 38 facial transplantations have been performed worldwide. We herein describe the surgical technique and 1-year clinical outcome in Finland's first face transplant case. METHODS: A 34-year-old male who had a severe facial deformity following ballistic trauma in 1999 underwent facial transplantation at the Helsinki University Hospital on 8th February 2016. Three-dimensional (3D) technology was used to manufacture donor and recipient patient-specific osteotomy guides and a donor face mask...
November 15, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29202764/influence-of-different-sample-preparation-strategies-on-the-proteomic-identification-of-stress-biomarkers-in-porcine-saliva
#18
Ana Gutiérrez, José Joaquín Cerón, Ebrahim Razzazi-Fazeli, Sarah Schlosser, Fernando Tecles
BACKGROUND: The influence of two different sample treatments comprising the enrichment of glycoproteins by boronic acid and dynamic range compression by hexapeptide libraries, on the detection of stress markers in saliva of pigs was evaluated in this study. For this purpose, saliva samples collected before and after the application of an acute stress model consisting of nasal restraining in pigs were processed without any treatment and with the two different treatments mentioned above...
December 4, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29202671/natural-lymphatic-atypical-actinobacillosis-in-cattle-caused-by-actinobacillus-lignieresii
#19
Rubén D Caffarena, Ana Rabaza, Laura Casaux, Melissa Macías Rioseco, Carlos O Schild, Cecilia Monesiglio, Martín Fraga, Federico Giannitti, Franklin Riet-Correa
Bovine actinobacillosis is typically characterized by pyogranulomatous glossitis (wooden tongue). The involvement of other tissues, generally the skin or lymph nodes, has been regarded as atypical or cutaneous. We describe herein 2 outbreaks of actinobacillosis affecting primarily the lymph nodes of the head and neck. The disease affected 40 of 540 lactating cows in a dairy herd and 5 of 335 two-y-old steers in a beef herd. Multiple or single, occasionally ulcerated nodules were observed in the region of the mandible, neck, and shoulder, including the parotid, submandibular, retropharyngeal, and prescapular lymph nodes...
December 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29197363/metastatic-retinoblastoma-of-the-parotid-and-submandibular-glands-a-rare-case-report
#20
Ping Wang, Yang-Jun Li, Shao-Bo Zhang, Qi-Lin Cheng, Qiong Zhang, Li-Sha He
BACKGROUND: Retinoblastoma is the most common intraocular malignancy occurring in children. It can metastasize to the regional lymph nodes, central nervous system and distant organs usually the bones and bone marrow and very rarely to the soft tissue. Here, we report a case of unilateral retinoblastoma in a 4-year-old girl accompanied by a large metastasis of the parotid and submandibular glands that developed about 6 months previously and gradually increased in size 5 months after enucleation of the left eye...
December 2, 2017: BMC Ophthalmology
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