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https://www.readbyqxmd.com/read/27918900/differential-gene-expression-in-the-condylar-cartilage-of-growing-rabbits-with-temporomandibular-joint-anterior-disk-displacement-a-transcriptomic-study
#1
Shuhua Wang, Liquan Deng, Ye Li, Huiling Wu, Zhiyuan Gu
Internal derangement (ID) in the temporomandibular joint (TMJ) comprises a group of clinical problems with relatively high prevalence. However, the temporal changes in gene expression of condylar cartilage during continuous ID remain unclear. The aim of the current study is to investigate by microarray analysis, the differentially-expressed gene pattern in condylar cartilage of rabbits with ID from one to eight weeks of ID progression. Histological results (hematoxylin and eosin staining) indicated that abnormal collagen fiber arrangements, fragmentation of fibrils, and inflammatory cell-infiltration were detected from one to four weeks in joint disc specimens, while newly formed vessels, mucoid degeneration, meniscal tears, and the presence of osteoclasts and osteoblasts were observed at later time points...
November 6, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27913901/3d-active-passive-response-of-human-knee-joint-in-gait-is-markedly-altered-when-simulated-as-a-planar-2d-joint
#2
H Marouane, A Shirazi-Adl, M Adouni
Musculoskeletal models of the lower extremity make a number of important assumptions when attempting to estimate muscle forces and tibiofemoral compartmental loads in activities such as gait. The knee is commonly idealized as a planar 2D joint in the sagittal plane with no consideration of motions and equilibrium in remaining planes. With muscle forces predicted, the static equilibrium in the frontal plane is then used to estimate compartmental loads neglecting also joint passive resistance and assuming condylar contact centers...
December 2, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27912927/effect-of-an-early-supervised-rehabilitation-programme-compared-with-home-based-exercise-after-temporomandibular-joint-condylar-discopexy-a-randomized-controlled-trial
#3
N Capan, S Esmaeilzadeh, A Karan, D Dıracoglu, U Emekli, A Yıldız, A Baskent, C Aksoy
The goal of rehabilitation after temporomandibular joint (TMJ) surgery is to achieve a normal range of motion. The aim of this study was to compare the impact of a comprehensive and early supervised rehabilitation programme with home-based exercise after TMJ condylar discopexy. Patients diagnosed with disc displacement without reduction were randomized to the study and control groups. After baseline assessments, the same surgical condylar discopexy procedure was applied to both groups. Following surgery, the study group patients underwent a supervised exercise programme conducted by a physiotherapist in the outpatient clinic...
November 29, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27904712/hyperbaric-oxygen-protects-mandibular-condylar-chondrocytes-from-interleukin-1%C3%AE-induced-apoptosis-via-the-pi3k-akt-signaling-pathway
#4
Hang Chen, Gaoyi Wu, Qi Sun, Yabing Dong, Huaqiang Zhao
Objectives: Mandibular condylar chondrocyte apoptosis is mainly responsible for the development and progression of temporomandibular joint osteoarthritis (TMJ-OA). Interleukin-1β (IL-1β) generally serves an agent that induces chondrocyte apoptosis. Hyperbaric oxygen (HBO) treatment increases proteoglycan synthesis in vivo. We explore the protective effect of HBO on IL-1β-induced mandibular condylar chondrocyte apoptosis in rats and the potential molecular mechanisms. Methods: Chondrocytes were isolated from the TMJ of 3-4-week old Sprague-Dawley rats...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27904221/what-have-we-learned-from-100-success-of-press-fit-condylar-rotating-platform-posterior-stabilized-knees-a-5-10-years-followup-by-a-nondesigner
#5
Shrinand V Vaidya, Siddharth Virani, Rajendra Phunde, Abhishek Mahajan
BACKGROUND: Total joint arthroplasties of the hip and knee represent a remarkable feat of modern medicine in terms of reducing pain and restoring function to millions of patients afflicted with severe arthritis. Oftentimes, the performance and longevity of new implants and devices are based on limited data. This is the first study by a non-designer on the press fit condylar rotating platform posterior stabilized (PFC-RP-PS) design with 100' success. This has a relevance, vis-á -vis bias that one may have in terms of reproducibility of technique and funding from the manufacturer...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27903449/sex-differences-in-the-estrogen-dependent-regulation-of-temporomandibular-joint-remodeling-in-altered-loading
#6
Jennifer L Robinson, Katelyn Cass, Ross Aronson, Thomas Choi, Manshan Xu, Ryan Buttenbaum, Hicham Drissi, Helen H Lu, Jing Chen, Sunil Wadhwa
OBJECTIVE: Temporomandibular joint (TMJ) diseases predominantly afflict women, suggesting a role of estrogen in the disease etiology. Previously, we determined that decreased occlusal loading (DOL) inhibited collagen type II (Col2) expression in the mandibular condylar cartilage (MCC) of female wild-type (WT) mice whereas no change was observed in males. This decrease in chondrogenesis was abolished by estrogen receptor beta (ERβ) deficiency in females. Therefore, the goal of this study was to examine the role of estradiol - ERβ signaling in mediating DOL effects in male mice to further decipher sex differences...
November 26, 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/27898628/fracture-and-nonaccidental-injury-a-case-report-of-a-lateral-condylar-fracture-in-a-13-month-old
#7
Helen Levin, Gurinder Sangha, Timothy P Carey, Rodrick Lim
Pediatric nonaccidental injury (NAI) is an important entity that is commonly seen in a variety of medical settings. These children often present to the emergency department or primary care physicians as the first point of contact after an NAI. There is a major risk associated with nonrecognition of an NAI, including a 35% chance of subsequent injury and a 5% to 10% risk of mortality. Therefore, it is essential for physicians to be vigilant when assessing injuries compatible with NAI, especially in infants and young children who are not able to independently express themselves...
December 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27896214/a-case-of-severe-mandibular-retrognathism-with-bilateral-condylar-deformities-treated-with-le-fort-i-osteotomy-and-two-advancement-genioplasty-procedures
#8
Masahiro Nakamura, Takeshi Yanagita, Tatsushi Matsumura, Takashi Yamashiro, Seiji Iida, Hiroshi Kamioka
We report a case involving a young female patient with severe mandibular retrognathism accompanied by mandibular condylar deformity that was effectively treated with Le Fort I osteotomy and two genioplasty procedures. At 9 years and 9 months of age, she was diagnosed with Angle Class III malocclusion, a skeletal Class II jaw relationship, an anterior crossbite, congenital absence of some teeth, and a left-sided cleft lip and palate. Although the anterior crossbite and narrow maxillary arch were corrected by interceptive orthodontic treatment, severe mandibular hypogrowth resulted in unexpectedly severe mandibular retrognathism after growth completion...
November 2016: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/27891668/systematic-mapping-of-the-subchondral-bone-3d-microarchitecture-in-the-human-tibial-plateau-variations-with-joint-alignment
#9
Bryant C Roberts, Dominic Thewlis, Lucian B Solomon, Graham Mercer, Karen J Reynolds, Egon Perilli
Tibial subchondral bone plays an important role in knee osteoarthritis (OA). Microarchitectural characterization of subchondral bone plate (SBP), underlying subchondral trabecular bone (STB) and relationships between these compartments, however, is limited. The aim of this study was to characterize the spatial distribution of SBP thickness, SBP porosity and STB microarchitecture, and relationships among them, in OA tibiae of varying joint alignment. Twenty-five tibial plateaus from end-stage knee-OA patients, with varus (n = 17) or non-varus (n = 8) alignment were micro-CT scanned (17 μm/voxel)...
November 7, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27891409/distal-femur-locking-plate-the-answer-to-all-distal-femoral-fractures
#10
Jagandeep Singh Virk, Sudhir Kumar Garg, Parmanand Gupta, Vivek Jangira, Jagdeep Singh, Sudhir Rana
INTRODUCTION: Good results have been published by researchers with distal femur nail, dynamic condylar screw and even addition of a medial plate to a distal femur locking plate for treating distal femur fractures. By this study, we explore the capability of a distal femur locking plate to counter distal femur fractures of extra- articular, partial or intra- articular nature. Positive results have been published by various groups from all over the world. AIM: To study the functional and radiological outcome of distal femoral fractures in skeletally mature patients treated by open reduction and internal fixation with distal femur locking plate...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891034/the-anatomical-perspective-of-human-occipital-condyle-in-relation-to-the-hypoglossal-canal-condylar-canal-and-jugular-foramen-and-its-surgical-significance
#11
Ranjana Verma, Shalini Kumar, Arpita Mahajan Rai, Iqra Mansoor, Raj D Mehra
BACKGROUND: The transcondylar approach (TCA) has gained importance in recent era which enables shorter and direct route to access the lesions ventral to the brainstem. The important step in this approach is resection of the occipital condyle (OC). The detailed knowledge of bony anatomy of OC and its relation to the hypoglossal canal (HC), condylar canal (CC), and jugular foramen (JF) is very important to avoid any iatrogenic injury during craniovertebral surgeries. The aim of the present study is to conduct a morphometric and morphological study and note the variations of the OC and the structures surrounding it in North Indian population...
October 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27888317/effect-of-tibial-slope-changes-on-femorotibial-contact-kinematics-after-cruciate-retaining-total-knee-arthroplasty
#12
Xi-Qing Pan, A-Qin Peng, Fei Wang, Feng Li, Xi-Zeng Nie, Xi Yang, Gang Ji, Xiao-Meng Wang
PURPOSE: The present study was undertaken to evaluate the effect of tibial slope (TS) changes on the femorotibial articular contact kinematics in subjects undergoing posterior cruciate-retaining total knee arthroplasty (CRTKA). METHODS: Eighteen knees in nine patients with medial osteoarthritis who underwent CRTKA using the same size prosthesis were analysed preoperatively and 2 years after TKA. TS changes were calculated on lateral radiographs taken before and after TKA...
November 25, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27886678/role-of-patellofemoral-offset-in-total-knee-arthroplasty-a-randomized-trial
#13
REVIEW
Louis S Stryker, Susan M Odum, Bryan D Springer, Thomas K Fehring
Total knee arthroplasty occasionally does not meet expectations. This randomized clinical trial assessed the effect of restoration of the native patellofemoral height on clinical outcomes. Group I underwent standard patellar bone resection; group II underwent modified patellar bone resection that adjusted the amount of anterior condylar bone removed and the anterior flange thickness. There were no differences in anterior knee pain, Western Ontario and McMaster Universities Arthritis Index scores, or Knee Injury and Osteoarthritis Outcome Score scores...
January 2017: Orthopedic Clinics of North America
https://www.readbyqxmd.com/read/27886399/simulation-of-total-knee-arthroplasty-in-5%C3%A2-or-7%C3%A2-valgus-a-study-of-gap-imbalances-and-changes-in-limb-and-knee-alignments-from-native
#14
Stephanie Gu, Stephen M Howell, Maury L Hull
This study calculated the frequency of occurrence of gap imbalances between medial and lateral compartments at 0° flexion and within a compartment between 0° and 90° flexion, and changes in limb and knee alignment from native after computer simulation of TKA with the knee set 5° or 7° valgus at 0° flexion. TKA was simulated on forty-nine 3D bone models of native limbs. At 0° flexion, the femoral component was set 5° or 7° valgus from the anatomic axis of the femur, and the tibial component was set 0° to the tibial anatomic axis...
November 25, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27873526/evaluation-of-complications-after-endoscopy-assisted-open-reduction-and-internal-fixation-of-unilateral-condylar-fractures-of-the-mandible-retrospective-analysis-2010-2015
#15
V Machoň, K Klíma, V Vlachopulos, J Valach, J Levorová, R Foltán
BACKGROUND: The authors present their experience with endoscopy assisted open reduction and internal fixation of condylar fractures of the mandible. Their results are presented in a retrospective study of 33 patients with unilateral subcondylar fracture, who underwent a surgical procedure between 2010 and 2015. Reduction and fixation, stability of occlusion 12 months after the operation and also presence of complications were evaluated. RESULTS: Satisfactory reduction (anatomic or physiologic) was achieved in 31 patients...
2016: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/27867065/condylar-resorptions-and-orthodontic-surgical-treatment-state-of-the-art
#16
Joël Ferri, Romain Nicot, Jean-Michel Maes, Gwénael Raoul, Ludovic Lauwers
Resorption of the mandibular condyle [RMC] is a disease of the temporomandibular joints, with multifactorial origins. The clinical manifestations take the form essentially of joint pain and occlusal disorders, depending on the rate at which the condyle is affected. X-ray imaging shows that the condyle is reduced in volume, flattened and displaced backwards, with loss of cortical substance in advanced forms. The aim of this article is to recall some pathophysiological features and then to review all the diagnostic and etiological factors and discuss possible modes of management...
November 17, 2016: International Orthodontics
https://www.readbyqxmd.com/read/27865479/evaluation-of-knee-functional-calibration-with-and-without-the-effect-of-soft-tissue-artefact
#17
Morgan Sangeux, Arnaud Barré, Kamiar Aminian
Functional calibration methods were devised to improve repeatability and accuracy of the knee flexion-extension axis, which is used to define the medio-lateral axis of the femur coordinate system in gait analysis. Repeatability of functional calibration methods has been studied extensively in healthy individuals, but not accuracy in the absence of a benchmark knee axis. We captured bi-plane fluoroscopy data of the knee joint in 17 subjects with unilateral total knee arthroplasty during treadmill walking. The prosthesis provided a benchmark knee axis to evaluate the functional calibration methods...
November 2, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27858071/-anatomy-of-temporomandibular-joint-and-condyle-position-in-uygur-adult-patients-evaluated-with-cone-beam-ct
#18
Jie-Rui Wang, Xu Pan, Cong-Bo Mi
PURPOSE: To compare the anatomy and condyle-fossa relationship difference between Uygur adult patients with Class I and Class II division 1 malocclusion by three dimensional cone-beam CT (CBCT). METHODS: Sixty-four patients with Class I and Class II division 1 malocclusion were selected, and the CBCT scans of their temporomandibular joints were taken.The difference of the condylar morphology and location between Class I and Class II division 1 patients was analyzed with SPSS 17...
August 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27855674/disk-displacement-eccentric-condylar-position-osteoarthrosis-misnomers-for-variations-of-normality-results-and-interpretations-from-an-mri-study-in-two-age-cohorts
#19
Jens C Türp, Anna Schlenker, Johannes Schröder, Marco Essig, Marc Schmitter
BACKGROUND: Clinical decision-making and prognostic statements in individuals with manifest or suspected temporomandibular disorders (TMDs) may involve assessment of (a) the position of articular disc relative to the mandibular condyle, (b) the location of the condyle relative to the temporal joint surfaces, and (c) the depth of the glenoid fossa of the temporomandibular joints (TMJs). The aim of this study was twofold: (1) Determination of the prevalence of these variables in two representative population-based birth cohorts...
November 17, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/27847157/occlusal-consequence-of-using-average-condylar-guidance-settings-an-in%C3%A2-vitro-study
#20
Wonsup Lee, Young-Jun Lim, Myung-Joo Kim, Ho-Beom Kwon
STATEMENT OF PROBLEM: A simplified mounting technique that adopts an average condylar guidance has been advocated. Despite this, the experimental explanation of how average settings differ from individual condylar guidance remains unclear. PURPOSE: The purpose of this in vitro study was to examine potential occlusal error by using average condylar guidance settings during nonworking side movement of the articulator. MATERIAL AND METHODS: Three-dimensional positions of the nonworking side maxillary first molar at various condylar and incisal settings were traced using a laser displacement sensor attached to the motorized stages with biaxial freedom of movement...
November 12, 2016: Journal of Prosthetic Dentistry
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