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https://www.readbyqxmd.com/read/28643917/estrogen-receptor-alpha-mediates-mandibular-condylar-cartilage-growth-in-male-mice
#1
J L Robinson, V Gupta, P Soria, E Clanaman, S Gurbarg, M Xu, J Chen, S Wadhwa
OBJECTIVES: In the appendicular skeleton, estrogen via ERα signalling has been shown to mediate endochondral growth plate fusion in both males and females. However, the role of ERα in mediating growth of the mandibular condylar cartilage is unknown. Thus, this study focuses on the characterization of the mandibular condylar cartilage phenotype in young and adult male ERαKO mice. SETTING: Columbia University Medical Center. MATERIAL AND METHODS: WT and ERαKO C57BL/6 male mice were sacrificed at 49 days or 9 months for phenotypic analysis...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28643904/pth-1-34-induced-alterations-predispose-the-mandibular-condylar-cartilage-to-mineralization
#2
E H Dutra, M H O'Brien, T Gutierrez, A Lima, R Nanda, S Yadav
OBJECTIVE: To study the effects of intermittent parathyroid hormone (PTH [1-34]) on the mandibular condylar cartilage (MCC) and subchondral bone in adult female mice. MATERIALS AND METHODS: Twenty-two, 20-week-old female mice were used for in vivo experiments. The experimental mice (n=11) received daily intraperitoneal injections of PTH [1-34] for 3 weeks, while control mice (n=11) received intraperitoneal injections of 0.9% saline solution. Mice were euthanized and then micro-computed tomography (micro-CT); histology and immunostaining were carried out to assess the response...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28642164/joint-loading-and-proximal-tibia-subchondral-trabecular-bone-microarchitecture-differ-with-walking-gait-patterns-in-end-stage-knee-osteoarthritis
#3
Bryant C Roberts, Lucian B Solomon, Graham Mercer, Karen J Reynolds, Dominic Thewlis, Egon Perilli
OBJECTIVES: To (1) stratify subgroups according to their distinct walking gait patterns in end-stage knee osteoarthritis (OA) patients; (2) compare measures of joint loading and proximal tibia subchondral trabecular bone (STB) microarchitecture among subgroups. DESIGN: Twenty-five knee OA patients undergoing total knee arthroplasty had pre-operative gait analysis. Following surgery, excised tibial plateaus were micro-CT-scanned and STB microarchitecture analysed in four tibial condylar regions of interest...
June 19, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28631937/the-effect-of-the-sagittal-ridge-angle-on-cartilage-stress-in-the-equine-metacarpo-phalangeal-fetlock-joint
#4
Helen Liley, Helen Davies, Elwyn Firth, Thor Besier, Justin Fernandez
Fatigue failure of bones of the metacarpo-phalangeal (fetlock, MCP) joint is common in thoroughbred racehorses. Stresses within the fetlock joint cartilages are affected by the morphology of the third metacarpal bone (MC3) and proximal phalangeal bone, and the steepness of the median sagittal ridge of MC3 is believed to be associated with fracture. This study investigated the influence of the steepness of the sagittal ridge on cartilage stress distribution using a finite element model of the joint. Changes to the steepness of the sagittal ridge were made by applying a parabolic function to the mesh, creating four different models with sagittal ridge angles ranging from 95° to 105°...
June 15, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28631024/the-use-of-tibial-tuberosity-trochlear-groove-indices-based-on-joint-size-in-lower-limb-evaluation
#5
Peter Wilhelm Ferlic, Armin Runer, Florian Dirisamer, Peter Balcarek, Johannes Giesinger, Rainer Biedermann, Michael Christian Liebensteiner
PURPOSE: The correlation between tibial tuberosity-trochlear groove distance (TT-TG) and joint size, taking into account several different parameters of knee joint size as well as lower limb dimensions, is evaluated in order to assess whether TT-TG indices should be used in instead of absolute TT-TG values. METHODS: This study comprised a retrospective analysis of knee CT scans, including 36 cases with patellofemoral instability (PFI) and 30 controls. Besides TT-TG, five measures of knee joint size were evaluated in axial CT slices: medio-lateral femur width, antero-posterior lateral condylar height, medio-lateral width of the tibia, width of the patella and the proximal-distal joint size (TT-TE)...
June 19, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28630773/functional-treatment-of-a-child-with-extracapsular-mandibular-fracture
#6
Diana Cassi, Marisabel Magnifico, Chiara Di Blasio, Mauro Gandolfini, Alberto Di Blasio
Condylar fractures are among the most frequent fractures in the context of traumatic lesions of the face. The management of condylar fractures is still controversial, especially when fractures occur in children: if overlooked or inappropriately treated, these lesions may lead to severe sequelae, both cosmetic and functional. The therapy must be careful because severe long-term complications can occur. In this case report, the authors present a case of mandibular fracture in which the decision between surgical therapy and functional therapeutic regimen may be controversial due to the particular anatomy of the fracture line and the age of the patient...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28615800/question-mark-ear-deformity-revisited
#7
Mohammad M Al-Qattan, Noha M Al-Qattan
We report on two unusual cases of Cosman (question mark) ear; both required modifications of the standard techniques for surgical correction. The first patient presented with a unilateral question mark ear and concurrent ear prominence and bulging of the cartilage of the anti-helix. Simultaneous correction was done using a combination of cartilage suturing/scoring (for the prominence and the cartilage bulge) as well as Al-Qattan's "v-y skin flap-cartilage graft-z-plasty" technique (for the correction of the ear cleft deformity)...
2017: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28613057/-analysis-of-factors-related-to-the-number-of-mesenchymal-stem-cells-derived-from-synovial-fluid-of-the-temporomandibular-joint
#8
Y P Sun, Y H Zheng, Z G Zhang
Objective: To analyze related factors on the number of mesenchymal stem cells in the synovial fluid of the temporomandibular joint (TMJ) and provide an research basis for understanding of the source and biological role of mesenchymal stem cells derived from synovial fluid in TMJ. Methods: One hundred and twenty-two synovial fluid samples from 91 temporomandibular disorders (TMD) patients who visited in Department of TMJ Center, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University from March 2013 to December 2013 were collected in this study, and 6 TMJ synovial fluid samples from 6 normal volunteers who were studying in the North Campus of Sun Yat-sen University were also collected, so did their clinical information...
June 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28611327/overgrowth-of-costochondral-graft-in-temporomandibular-joint-ankylosis-reconstruction-a-retrospective-study
#9
S M Balaji, Preetha Balaji
BACKGROUND: Temporomandibular joint (TMJ) ankylosis is a situation in which the mandibular condyle is fused to the glenoid fossa by bone or fibrous tissue. The management of TMJ ankylosis has a complicated chore, and it is challenging for the maxillofacial surgeon because of technical hitches and high rate of reankylosis. Costochondral graft (CCG) is a common treatment modality for TMJ ankylosis. One of disadvantages of CCG is unpredictability of growth pattern and risk of overgrowth...
March 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28610080/revision-of-the-i-ephippiochthonius-i-complex-in-the-iberian-peninsula-%C3%A2-balearic-islands-and-macaronesia-with-proposed-changes-to-the-status-of-the-i-chthonius-i-subgenera-pseudoscorpiones-chthoniidae
#10
Juan A Zaragoza
A taxonomic revision of the subgenus Chthonius (Ephippiochthonius) in the Iberian Peninsula, Balearic Islands and    Macaronesia is presented. New and previously insufficiently studied characteristics are shown to be taxonomically useful, such as the chelal lyrifissures patterns, chaetotaxy and condylar complex. Three taxa previously treated as subgenera of Chthonius are here raised to generic rank: Ephippiochthonius n. stat., Globochthonius n. stat., and Hesperochthonius n. stat. Two new genera are described: Cantabrochthonius n...
March 23, 2017: Zootaxa
https://www.readbyqxmd.com/read/28607469/pth-1-34-induced-differentiation-and-mineralization-of-mandibular-condylar-cartilage
#11
Mara Heather O' Brien, Eliane Hermes Dutra, Alexandro Lima, Ravindra Nanda, Sumit Yadav
Intermittent Parathyroid Hormone (I-PTH) is the only FDA approved anabolic drug therapy available for the treatment of osteoporosis in males and postmenopausal females. The effects of I-PTH on the chondrogenic lineage of the mandibular condylar cartilage (MCC) are not well understood. To investigate the role of I-PTH on the MCC and subchondral bone, we carried out our studies using 4 to 5 week old triple transgenic mice (Col1a1XCol2a1XCol10a1). The experimental group was injected with PTH (80 μg/kg) daily for 2 weeks, while control group was injected with saline...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28601246/clinical-outcome-of-medial-pivot-compared-with-press-fit-condylar-sigma-cruciate-retaining-mobile-bearing-total-knee-arthroplasty
#12
Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim
BACKGROUND: The purpose of this study was to compare the long-term clinical results, radiographic results, range of knee motion, patient satisfaction, and the survival rate of Medial-Pivot posterior cruciate-substituting, knee prosthesis and a press-fit condylar (PFC) Sigma cruciate-retaining mobile-bearing knee prosthesis in the same patients. METHODS: One hundred eighty-two patients received Medial-Pivot knee prosthesis in one knee and a PFC Sigma knee prosthesis in the contralateral knee...
May 18, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28600917/application-of-combined-osteotomy-and-reconstruction-pre-bent-plate-position-corppp-technology-to-assist-in-the-precise-reconstruction-of-segmental-mandibular-defects
#13
Ye Liang, Canhua Jiang, Limeng Wu, Wenjin Wang, Yonggang Liu, Xinchun Jian
PURPOSE: To introduce and evaluate the clinical effects of digital surgical guide plate technology in the combined osteotomy and reconstruction pre-bent plate position (CORPPP) technique during mandibular segmental resections. MATERIALS AND METHODS: Seven cases of mandibular segmental resection with simultaneous vascularized free fibula flap reconstruction by oral and maxillofacial surgery were selected (Xiangya Hospital, Changsha, China; June 2015 through December 2015)...
May 15, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28598184/surface-electromyography-before-and-after-orthognathic-surgery-and-condylectomy-in-active-laterognathia-a-case-report
#14
F Cullati, A Mapelli, G Beltramini, M Codari, C L Pimenta Ferreira, A Baj, A B Giannì, C Sforza
BACKGROUND: Condylar hyperplasia is a rare bone disease characterised by excessive development of mandibular condyle, which can lead to the development of asymmetric facial deformity together with malocclusion, mandibular deviation, TMJ and masticatory musculoskeletal system dysfunction. There is not a treatment protocol universally accepted. In order to determine the correct management, treatment and intervention timing of these patients, morphological examinations should be coupled with functional assessments...
June 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28587889/corrigendum-to-an-anatomic-investigation-into-the-relationship-between-posterior-condylar-offset-and-posterior-tibial-slope-of-one-thousand-one-hundred-thirty-eight-cadaveric-knees-the-journal-of-arthroplasty-32-2017-1659-1664
#15
https://www.readbyqxmd.com/read/28584510/evaluation-of-mandibular-condylar-changes-in-patients-following-orthognathic-surgery-a-retrospective-study
#16
Vikas Aneja, Rushik Raval, Parul Aneja, K K Rai, Sumit Agarwal, Satyapal Chuadhary
BACKGROUND: Condylar resorption as a cause of relapse after orthognathic surgery is well known. Several authors have presented evidence of the relation between orthognathic surgery and condylar remodeling and resorption. This study was done to appraise the condylar changes along with the form and function following orthognathic surgery, as well as to assess what factors may have contributed to the problems. METHODOLOGY: A diagnosis of progressive condylar resorption (PCR) was made by comparison of preoperative and postoperative radiographs (cephalometric radiograms), as well as clinical evaluations...
January 2017: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/28584419/a-comparative-study-to-correlate-between-clinically-and-radiographically-determined-sagittal-condylar-guidance-in-participants-with-different-skeletal-relationships
#17
Sweta Singh, Samiran Das, Jayanta Bhattacharyya, Soumitra Ghosh, Preeti Goel, Kaushik Dutta
CONTEXT: Many authors have conducted studies that determine horizontal condylar guidance (HCG) using various methods, articulator systems, and recording materials. However, there is a dearth of literature on variability existing in HCG in individuals with different skeletal relationships. This study is an attempt to verify whether such a difference exists or not. AIMS: The aim of this study is to determine and correlate the HCG in individuals with Angle's Class I, Class II, and Class III malocclusion using radiographic and clinical methods...
April 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/28584413/idiopathic-condylar-resorption-the-current-understanding-in-diagnosis-and-treatment
#18
REVIEW
Andrew Young
Idiopathic condylar resorption (ICR) is a condition with no known cause, which manifests as progressive malocclusion, esthetic changes, and often pain. Cone-beam computed tomography and magnetic resonance imaging are the most valuable imaging methods for diagnosis and tracking, compared to the less complete and more distorted images provided by panoramic radiographs, and the higher radiation of (99m)technetium-methylene diphosphonate. ICR has findings that overlap with osteoarthritis, inflammatory arthritis, physiologic resorption/remodeling, congenital disorders affecting the mandible, requiring thorough image analysis, physical examination, and history-taking...
April 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/28583898/associations-between-proximal-tibiofibular-joint-ptfj-types-and-knee-osteoarthritic-changes-in-older-adults
#19
M Lu, W Han, K Wang, Z Zhu, B Antony, F Cicuttini, Z Yin, G Jones, C Ding
PURPOSE: To describe the cross-sectional associations between proximal tibiofibular joint (PTFJ) type configurations and knee joint structural abnormalities in older adults. METHODS: A total of 967 community-based participants were studied. T1-weighted fat-suppressed magnetic resonance image (MRI) with spoiled gradient recalled echo sequence was utilized to assess the PTFJ type configurations. Knee cartilage volume, cartilage defects, bone marrow lesions and osteophytes were measured...
June 3, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28579246/neocondylar-formation-after-resection-of-the-mandible-and-reconstruction-with-a-vascularised-iliac-crest-free-flap-rare-case
#20
S Bin, Z Bin, D Baoxia, W Yue, Z Wei
Tumours in the mandible often necessitate the removal of both mandibular and condylar bone. A free vascularised bone flap is a common choice for reconstruction, but it is rare for adults to form a new condyle after it. We describe a patient in whom a new condyle did form after reconstruction with a vascularised iliac crest free flap.
June 1, 2017: British Journal of Oral & Maxillofacial Surgery
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