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JOURNAL ARTICLE
A I Maksimkin, Z A Bagatelia, V M Kulushev, E N Gordienko, M S Lebedko, S S Anikina, E P Shin
OBJECTIVE: To analyze morphological changes in wall of functioning and non-functioning small intestine in patients with preventive ileostomy and to determine histological predictors of water-electrolyte disorders. MATERIAL AND METHODS: We prospectively analyzed 57 patients >18 years old who underwent rectal resection with preventive ileostomy between January 2022 and November 2023. Anthropometric data included gender, age, body mass index, ECOG and ASA classes...
2024: Khirurgiia
#2
JOURNAL ARTICLE
Paul Rogers, Dong Wang, Zhiyuan Lu, Beverly Lyn-Cook
Purpose: In 2005, the Food and Drug Administration (FDA) issued a decision memorandum regarding nonsteroidal anti-inflammatory drugs (NSAIDs). The memorandum recommended the withdrawal of certain NSAIDs due to potential cardiovascular adverse effects. It highlighted the issue of cardiovascular risk associated with NSAIDs as a class. The NSAID medication guide includes a wide range of adverse drug reactions (ADRs), such as increased blood pressure, liver failure, allergic reactions, heart attack, and intestinal bleeding...
April 18, 2024: Journal of Women's Health
#3
JOURNAL ARTICLE
Sawsan S Elbasuni, Hanan A A Taie, Samah M Abdel Gawad, Reda E L Kamar, Hala El Daous, Marwa Darweish, Mai O Nada, Walaa F SaadEldin, Marwa I Abdel Haleem
BACKGROUND: Coccidiosis is one of the most economically significant poultry diseases worldwide, caused by the pathogenic Eimeria species, and is characterized by decreased weight gain (WG) and failure to grow due to malabsorption, low feed conversion rate, bloody diarrhea, and dehydration. AIM: This study investigated the effectiveness of licorice root extract (LRE) in controlling cecal coccidiosis to determine whether its combination with maduramicin could help alleviate the pathological, biochemical, and histopathological effects of cecal coccidiosis in Sasso broiler chicks...
January 2024: Open Veterinary Journal
#4
JOURNAL ARTICLE
Mohamed Abouzid, Ahmed Abdelhakeem, Shorouk Elshafie, Ahmad Ghorab
We present the case of an elderly man with a history of diastolic congestive heart failure, severe aortic stenosis and atrial fibrillation, who presented with fatigue, weakness, coffee ground emesis and black tarry stool. Haemoglobin was 68 g/L. Lactate dehydrogenase was elevated at 1038. Evaluation by cardiology and gastroenterology specialists revealed reflux oesophagitis and a mild hiatal hernia on oesophagogastroduodenoscopy, normal colonoscopy and small bowel series without obstruction. Capsule endoscopy identified angiodysplasia in the small intestine...
April 17, 2024: BMJ Case Reports
#5
JOURNAL ARTICLE
Masatomo Ogata, Masaki Kato, Takamasa Miyauchi, Marie Murata-Hasegawa, Yuko Sakurai, Kazunobu Shinoda, Hajime Yamazaki, Yugo Shibagaki, Masahiko Yazawa
INTRODUCTION: Gastrointestinal complications are common after solid organ transplantation. New-onset inflammatory bowel disease (IBD) after transplantation (de novo) is a major differential diagnosis of diarrhea after liver transplantation (LT) because of its high incidence in the field. However, the incidence of IBD after kidney transplantation (KT) remains unknown. METHODS: This case series comprised six de novo IBD patients who had undergone KT at our hospital from April 1998 to December 2020...
2024: Inflammatory Intestinal Diseases
#6
JOURNAL ARTICLE
Clarisse Billon, Giorgina Barbara Piccoli, Jean-Madeleine de Sainte Agathe, Radka Stoeva, Nicolas Derive, Laurence Heidet, Dominique Berrebi, Patrick Bruneval, Xavier Jeunemaitre, Marguerite Hureaux
Megacystis-microcolon-hypoperistalsis-syndrome (MMIHS) is a rare and early-onset congenital disease characterized by massive abdominal distension due to a large non-obstructive bladder, a microcolon and decreased or absent intestinal peristalsis. While in most cases inheritance is autosomal dominant and associated with heterozygous variant in ACTG2 gene, an autosomal recessive transmission has also been described including pathogenic bialellic loss-of-function variants in MYH11. We report here a novel family with visceral myopathy related to MYH11 gene, confirmed by whole genome sequencing (WGS)...
April 16, 2024: Molecular Genetics and Genomics: MGG
#7
REVIEW
Vikram K Raghu, Carolina Rumbo, Simon P Horslen
INTRODUCTION: Intestinal failure, defined as the loss of gastrointestinal function to the point where nutrition cannot be maintained by enteral intake alone, presents numerous challenges in children, not least the timing of consideration of intestine transplantation. OBJECTIVES: To describe the evolution of care of infants and children with intestinal failure including parenteral nutrition, intestine transplantation, and contemporary intestinal failure care. METHODS: The review is based on the authors' experience supported by an in-depth review of the published literature...
May 2024: Pediatric Transplantation
#8
JOURNAL ARTICLE
Nguyen Thi Khanh Nhu, Minh-Duy Phan, Steven J Hancock, Kate M Peters, Laura Alvarez-Fraga, Brian M Forde, Stacey B Andersen, Thyl Miliya, Patrick N A Harris, Scott A Beatson, Sanmarie Schlebusch, Haakon Bergh, Paul Turner, Annelie Brauner, Benita Westerlund-Wikström, Adam D Irwin, Mark A Schembri
Neonatal meningitis is a devastating disease associated with high mortality and neurological sequelae. Escherichia coli is the second most common cause of neonatal meningitis in full-term infants (herein NMEC) and the most common cause of meningitis in preterm neonates. Here, we investigated the genomic relatedness of a collection of 58 NMEC isolates spanning 1974-2020 and isolated from seven different geographic regions. We show NMEC are comprised of diverse sequence types (STs), with ST95 (34.5%) and ST1193 (15...
April 16, 2024: ELife
#9
JOURNAL ARTICLE
Jinxia Liu, Jane MacNaughtan, Annarein J C Kerbert, Theo Portlock, Javier Martínez Gonzalez, Yi Jin, Frederick Clasen, Abeba Habtesion, Huoyan Ji, Qin Jin, Alexandra Phillips, Francesco De Chiara, Ganesh Ingavle, Cesar Jimenez, Giacomo Zaccherini, Katherine Husi, Miguel Angel Rodriguez Gandia, Paul Cordero, Junpei Soeda, Lynda McConaghy, Jude Oben, Karen Church, Jia V Li, Haifeng Wu, Aarti Jalan, Pere Gines, Elsa Solà, Simon Eaton, Carrie Morgan, Michal Kowalski, Daniel Green, Amir Gander, Lindsey A Edwards, I Jane Cox, Helena Cortez-Pinto, Thomas Avery, Reiner Wiest, Francois Durand, Paolo Caraceni, Roberto Elosua, Joan Vila, Marco Pavesi, Vicente Arroyo, Nathan Davies, Rajeshwar P Mookerjee, Victor Vargas, Susan Sandeman, Gautam Mehta, Saeed Shoaie, Julian Marchesi, Agustín Albillos, Fausto Andreola, Rajiv Jalan
OBJECTIVE: Targeting bacterial translocation in cirrhosis is limited to antibiotics with risk of antimicrobial resistance. This study explored the therapeutic potential of a non-absorbable, gut-restricted, engineered carbon bead adsorbent, Yaq-001 in models of cirrhosis and acute-on-chronic liver failure (ACLF) and, its safety and tolerability in a clinical trial in cirrhosis. DESIGN: Performance of Yaq-001 was evaluated in vitro . Two-rat models of cirrhosis and ACLF, (4 weeks, bile duct ligation with or without lipopolysaccharide), receiving Yaq-001 for 2 weeks; and two-mouse models of cirrhosis (6-week and 12-week carbon tetrachloride (CCl4)) receiving Yaq-001 for 6 weeks were studied...
April 15, 2024: Gut
#10
JOURNAL ARTICLE
Xin-Yu Xu, Jun Zhou
Prostate cancer is the most common malignant tumor of male genitourinary system, its morbidity and mortality increase year by year, and has become a public health problem affecting male health. Mendelian randomization （MR） analysis has been widely used in epidemiological etiology inference in recent years. Compared with general observational studies, it avoids the interference of confounding factors and has clear causal sequence. The judgment of disease risk factors is more helpful for early intervention and clinical prevention and treatment of diseases...
July 2023: Zhonghua Nan Ke Xue, National Journal of Andrology
#11
JOURNAL ARTICLE
Bindira Joshi, Santosh Kumar Yadav, Manju Shree Shakya Hada, Sabina Shrestha, Kalpana Kumari Shrestha, Pukar Chandra Shrestha, Bal Krishna Awal
BACKGROUND: The intestinal colonization and transmission of antibiotic-resistant Enterobacteriales to renal transplant recipients may pose a threat to them because they are profoundly immunocompromised and vulnerable to infection. Hence, it is crucial to identify these antibiotic-resistant fecal Enterobacteriales harboring high-risk populations. The objective of this study was to determine antibiotic resistance as well as β-lactamases production in fecal Enterobacteriales among renal transplant recipients...
March 31, 2024: Journal of Nepal Health Research Council
#12
JOURNAL ARTICLE
Kathryn M Maselli, Irene C Carter, Niki Matusko, Seth Warschausky, Allison B Blackmer, Saleem Islam, Michael D Rollins, Patrick J Javid, Meghan A Arnold
INTRODUCTION: Reducing soybean lipid emulsion (SLE) dose may prevent parenteral nutrition-associated cholestasis (PNAC) but effects on growth and neurodevelopment are unknown. The purpose of this study was to evaluate the effect of reduced dose SLE on growth and neurodevelopment. METHODS: Surgical neonates at 4 centers were randomized to standard SLE (3 g/kg/day) or reduced SLE (1 g/kg/day) over a 12-week period. Bilirubin levels and growth parameters were measured baseline and weekly while on study...
March 17, 2024: Journal of Pediatric Surgery
#13
JOURNAL ARTICLE
Victória A Alves, Juliana M Giesta, Vera L Bosa, Helena A S Goldani
OBJECTIVE: To compare the phase angle (PhA) through bioelectrical impedance (BIA) of children with intestinal failure (IF) using prolonged parenteral nutrition (PN) followed by an Intestinal Rehabilitation Program, with a control group. METHODS: Children under 10 years of age with IF using prolonged PN for >60 days (study group) were included. The control group consisted of healthy children without chronic pathologies, matched by sex and age. Anthropometric parameters evaluated were: weight, height, weight/age z-score (W/A), height/age z-score (H/A), BMI, BMI/A z-score, arm circumference, triceps skinfold, subscapular skinfold, mid-arm muscle circumference...
April 10, 2024: Jornal de Pediatria
#14
Liang Zhang, Hui Chen, Yulin Ding, Wenlong Wang, Gao Wa, Bingwu Zheng, Jinling Wang
BACKGROUND: Feline pulmonary Langerhans cells histiocytosis (PLCH) is a rare disorder that results in progressive respiratory failure secondary to pulmonary parenchymal infiltration with Langerhans cells (LCs). A diagnosis of PLCH is proposed based on the clinical features and pathological findings and confirmed based on the infiltrating histiocytic cells. There are few documented cases of feline PLCH, and this case report of PLCH in an African Lion could present new information and aspects of this feline histiocytic disease...
March 26, 2024: Animals: An Open Access Journal From MDPI
#15
Đorđe Todorovic, Bojan Stojanovic, Milutinovic Filip, Đorđe Đorđevic, Milos Stankovic, Ivan Jovanovic, Marko Spasic, Bojan Milosevic, Aleksandar Cvetkovic, Dragce Radovanovic, Marina Jovanovic, Bojana S Stojanovic, Damnjan Pantic, Danijela Cvetkovic, Dalibor Jovanovic, Vladan Markovic, Milica Dimitrijevic Stojanovic
This case report presents a unique instance of small bowel perforation caused by solitary metastasis from renal cell carcinoma (RCC), a rare and complex clinical scenario. The patient, a 59-year-old male with a history of RCC treated with nephrectomy four years prior, presented with acute abdomen symptoms. Emergency diagnostic procedures identified a significant lesion in the small intestine. Surgical intervention revealed a perforated jejunal segment due to metastatic RCC. Postoperatively, the patient developed complications, including pneumonia and multi-organ failure, leading to death 10 days after surgery...
April 3, 2024: Diagnostics
#16
JOURNAL ARTICLE
Yu Norimatsu, Nobuyuki Takemura, Kaoru Yoshikawa, Kyoji Ito, Fuyuki Inagaki, Fuminori Mihara, Kazuhiko Yamada, Norihiro Kokudo
BACKGROUND: Pylephlebitis, a rare and lethal form of portal venous septic thrombophlebitis, often arises from infections in regions drained by the portal vein. Herein, we report a case of peritonitis with portal vein thrombosis due to acute severe appendicitis, managed with intensive intraperitoneal drainage via open abdominal management (OAM). CASE PRESENTATION: A 19-year-old male with severe appendicitis, liver abscesses, and portal vein thrombosis developed septic shock and multi-organ failure...
April 12, 2024: Surgical Case Reports
#17
Tianlong Li, Xiaoxiao Wu, Tingrui Chen, Chun Pan, Ruiming Yue, Chunlin Xiang, Tao Yu, Zhenjie Jiang, Xiaobo Huang, Xuemei Tang, Yiping Wang
Early-stage infective endocarditis (IE) can lead to severe complications, including infarctions and metastatic infections caused by inflammatory embolus shedding. Common embolism sites include the brain, spleen, kidneys, lungs, and intestines. Additionally, acute heart failure (AHF) can occur in up to 40% of cases, and its presence can impact the clinical outcomes of patients with IE. Cardiogenic shock (CGS) is often more likely to occur after AHF has taken place. If bacteria invade the blood, infectious shock can occur...
2024: Frontiers in Cardiovascular Medicine
#18
JOURNAL ARTICLE
Aysenur Demirok, David H C Illy, Sietse Q Nagelkerke, Michiel F Lagerweij, Marc A Benninga, Merit M Tabbers
BACKGROUND: Children with chronic IF require long-term home parenteral nutrition (HPN), administered through a central venous catheter. Catheter-related bloodstream infection (CRBSI) with Staphylococcus aureus is known to be a serious infection with a high mortality rate and risk of complications. A standardized protocol on the management of S aureus CRBSIs in children receiving HPN is lacking. The aim of this study is to evaluate the effectiveness and safety of the current management in an HPN expertise center in the Netherlands...
April 11, 2024: JPEN. Journal of Parenteral and Enteral Nutrition
#19
Gašper Razinger, Nada Rotovnik Kozjek
INTRODUCTION: Caustic injuries remain a major public health concern. Nutritional status plays a pivotal role in determining the outcome. Unfortunately, nutritional care guidelines are not widely implemented in clinical practice, and decisions are often based on prior experience and local policies. CASE PRESENTATION: We present the case of an 83-year-old man who accidentally ingested alkali, resulting in severe caustic injury and subsequent complications that further deteriorated his nutritional status...
2024: Case Reports in Gastroenterology
#20
REVIEW
Francisco Alejandro Lagunas-Rangel
Giardia duodenalis, the protozoan responsible for giardiasis, is a significant contributor to millions of diarrheal diseases worldwide. Despite the availability of treatments for this parasitic infection, therapeutic failures are alarmingly frequent. Thus, there is a clear need to identify new therapeutic targets. Giardia telomeres were previously identified, but our understanding of these structures and the critical role played by Giardia telomerase in maintaining genomic stability and its influence on cellular processes remains limited...
April 8, 2024: Parasitology Research
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