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Tolga Altuğ Şen, Reşit Köken, Adnan Narcı, Mehmet Yılmazer
AIM: Elevated levels of plasma homocysteine and depressed ghrelin levels have been found to be associated with insulin resistance in a number of clinical situations, such as polycystic ovary syndrome. This study was designed to determine the relationship of plasma homocysteine and ghrelin levels with obesity in polycystic ovary syndrome. MATERIAL AND METHODS: Forty-four adolescents and young women (24 lean, 20 obese) 16-21 years old with polycystic ovary syndrome and age matched 20 healthy adolescents and young women were participated the study...
August 2011: Journal of Pediatric and Adolescent Gynecology
Carlos G Galindo, Imelda Hernández, Aquiles R Ayala
OBJECTIVE: To verify the medical effects of metformin in polycystic ovary syndrome patients. METHOD: 10 women with polycystic ovary syndrome were including in this prospective clinical study. After a baseline workup, body mass index (BMI) and waist hip index (WHI) were measured; the diagnosis of polycystic ovary syndrome was achieved with the following basal clinical studies: vaginal ultrasound, prolactin, thyroid profile, glucose, insulin, testosterone, androstenedione, 17-hidroxiprogesterone, dehydroepiandrosterone sulfate and cortisol...
April 2007: Ginecología y Obstetricia de México
S Hahn, W Bering van Halteren, S Roesler, M Schmidt, R Kimmig, S Tan, K Mann, O E Janssen
The prevalence and relevance of polycystic ovaries (PCO) in German women with polycystic ovary syndrome has not been evaluated. This retrospective study included 212 PCOS patients (mean age 28 years) diagnosed by the NIH-criteria and consecutively recruited since 2003. Clinical features including anthropometric variables and the degree of hirsutism, family history, menstrual cyclicity as well as endocrine biochemical parameters were recorded. In addition, 3-h oral glucose tolerance testing for indices of insulin resistance and glucose metabolism was performed in each patient...
April 2006: Experimental and Clinical Endocrinology & Diabetes
R Krepler, G Weissenbacher, S Leodolter, E Müller-Tyl
Besides classical achondroplasia various severe osteochondrodysplastic disorders have been differentiated in recent years. Their most important features include obligatory perinatal mortality, severe dystrophy of the thorax and shortening of tubular bones. Additionally some of these syndromes present visceral malformations, cleft-lip, and malformations of the genitals. A detailed case report of a patient is given. Various features: dystrophy of the thorax, micromelia, postaxial polydactyly, metaphyseal dysplasia, malformations of the great vessels, and polcystic kidney suggest the classification as short rib-polydactyly syndrome, type Saldino-Noonan...
April 1976: Monatsschrift Für Kinderheilkunde
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