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Multimorbidity

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https://www.readbyqxmd.com/read/29667565/longitudinal-associations-between-different-dementia-diagnoses-and-medication-use-jointly-accounting-for-dropout
#1
George O Agogo, Christine M Ramsey, Danijela Gnjidic, Daniela C Moga, Heather Allore
ABSTRACTBackground:Longitudinal studies of older adults are characterized by high dropout rates, multimorbid conditions, and multiple medication use, especially proximal to death. We studied the association between multiple medication use and incident dementia diagnoses including Alzheimer's disease (AD), vascular dementia (VD), and Lewy-body dementia (LBD), simultaneously accounting for dropout. METHODS: Using the National Alzheimer's Coordinating Center data with three years of follow-up, a set of covariate-adjusted models that ignore dropout was fit to complete-case data, and to the whole-cohort data...
April 18, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29660933/medical-comorbidity-in-alzheimer-s-disease-a-nested-case-control-study
#2
Jen-Hung Wang, Ya-Ju Wu, Boon Lead Tee, Raymond Y Lo
BACKGROUND: Little is known about the distribution of medical comorbidities in Alzheimer's disease (AD). OBJECTIVE: We aimed to describe the comorbidity pattern of AD in a nested case-control study. METHODS: Incident AD cases were identified by International Classification of Diseases codes in a random sample of 2 million individuals in Taiwan National Health Insurance program during 2001-2011. We further restricted cases to those treated with AD drugs of approved reimbursement...
April 11, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29656837/long-term-care-status-in-centenarians-and-younger-cohorts-of-oldest-old-in-the-last-6-years-of-life-trajectories-and-potential-mechanisms
#3
Paul Gellert, Simon Eggert, Christine Zwillich, Stefan Hörter, Adelheid Kuhlmey, Dagmar Dräger
OBJECTIVES: A large proportion of the oldest old and centenarians live in long-term care facilities. Although there may be distinct care patterns in centenarians compared with other cohorts of oldest old, the exact development concerning prevalence, length of stay, and factors that are associated with long-term care status in the last years before death is unknown. DESIGN: Longitudinal analyses of health insurance data across 6 years before death. SETTING AND PARTICIPANTS: In all, 1398 institutionalized and noninstitutionalized oldest old [deceased at 80-89 (octogenarians), 90-99 (nonagenarians), or over 100 years of age (centenarians)] from Germany were included...
April 13, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29656262/corrigendum-to-post-traumatic-stress-symptoms-are-associated-with-physical-multimorbidity-findings-from-the-adult-psychiatric-morbidity-survey-2007-journal-of-affective-disorders-232-2018-385-392
#4
Louis Jacob, Josep Maria Haro, Ai Koyanagi
No abstract text is available yet for this article.
April 12, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29653198/the-m3-multimorbidity-index-outperformed-both-charlson-and-elixhauser-indices-when-predicting-adverse-outcomes-in-people-with-diabetes
#5
Jason K Gurney, James Stanley, Diana Sarfati
OBJECTIVE: Multimorbidity is common among those living with diabetes. The purpose of this manuscript was to assess the performance of the recently developed M3 multimorbidity index within a large, well-defined cohort of patients with diabetes. STUDY DESIGN AND SETTING: We compared regression model performance between three morbidity indices (M3, Charlson, Elixhauser) for important adverse outcomes (hospitalisation, amputation, and mortality) among 217,207 patients with diabetes, and compared the real-world applied impact of these indices for modelling these diabetes outcomes against two key exposure variables (ethnicity and deprivation)...
April 10, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29651743/polypharmacy-in-palliative-care-copd-and-multimorbidity-a-case-report
#6
Marcel Rowhani, Bernhard Iglseder
This is the case report of an 80-year-old woman with advanced chronic obstructive pulmonary disease (COPD), multimorbidity and frailty. Despite regular critical re-evaluation of on-going medication, a significant reduction of prescribed medication was not achieved up until the patient's terminal phase, and this may have contributed to several episodes of delirium. It was particularly difficult to reduce the number of prescribed drugs due to cardiovascular, endocrinologic, orthopaedic, neurologic, psychiatric and pulmonary comorbidities...
April 12, 2018: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29651408/patients-with-multimorbidity-and-their-treatment-burden-in-different-daily-life-domains-a-qualitative-study-in-primary-care-in-the-netherlands-and-belgium
#7
Tiny van Merode, Karin van de Ven, Marjan van den Akker
Background: Physicians and other healthcare professionals involved in the care of patients with multimorbidity should consider the problems these patients experience in managing their own conditions. However, treatment burden from the patient's perspective has been poorly explored, even though this might hamper treatment adherence. Objective: The present study examined the experiences of patients with multimorbidity in primary care in the Netherlands and Belgium using semi-structured interviews, with special attention to the daily life domains of treatment burden...
2018: Journal of Comorbidity
https://www.readbyqxmd.com/read/29651127/testosterone-deficiency-weakness-and-multimorbidity-in-men
#8
Mark D Peterson, Aleksandr Belakovskiy, Ryan McGrath, Joshua F Yarrow
The purposes of this study were to evaluate the association between total testosterone (TT) deficiency and weakness on multimorbidity in men. Analyses were performed to examine the prevalence of multimobidity among young, middle-aged, and older men, with and without testosterone deficiency. Multivariate logistic models were also used to determine the association between age-specific TT tertiles and multimorbidity, adjusting for key sociodemographic variables, as well as a secondary analysis adjusted for grip strength...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29649895/the-impact-of-overweight-obesity-duration-and-physical-activity-on-medical-multimorbidity-examining-the-watch-paradigm
#9
Scott J Dankel, Jeremy P Loenneke, Paul D Loprinzi
PURPOSE: The "fat-but-fit" paradigm has been evaluated. However, the duration of overweight/obesity within the "fat-but-fit" paradigm (ie, assessing body mass at more than 1 time point) has not been extensively evaluated, which was this study's purpose. DESIGN: Cross-sectional. SETTING: National Health and Nutrition Examination Survey 2003 to 2006. PARTICIPANTS: Ages 36 to 85; N = 3621. MEASURES: Physical activity assessed via accelerometry...
January 1, 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29649323/prognosis-of-cardiovascular-and-non-cardiovascular-multimorbidity-after-acute-coronary-syndrome
#10
Silvia Canivell, Olivier Muller, Baris Gencer, Dik Heg, Roland Klingenberg, Lorenz Räber, David Carballo, Christian Matter, Thomas Lüscher, Stephan Windecker, François Mach, Nicolas Rodondi, David Nanchen
OBJECTIVE: To examine the prognosis of patients with cardiovascular and non-cardiovascular multimorbidity after acute coronary syndrome compared to patients without prior multimorbidity. METHODS: This multicenter prospective cohort study in Switzerland included 5,635 patients hospitalized with acute coronary syndrome between 2009 and 2014, with a one-year follow-up period. We defined cardiovascular and non-cardiovascular multimorbidity as having at least two prior comorbidities before the index hospitalization...
2018: PloS One
https://www.readbyqxmd.com/read/29644927/disease-specific-clinical-pathways-are-they-feasible-in-primary-care-a-mixed-methods-study
#11
Anders Grimsmo, Audhild Løhre, Tove Røsstad, Ingunn Gjerde, Ina Heiberg, Aslak Steinsbekk
OBJECTIVE: To explore the feasibility of disease-specific clinical pathways when used in primary care. DESIGN: A mixed-method sequential exploratory design was used. First, merging and exploring quality interview data across two cases of collaboration between the specialist care and primary care on the introduction of clinical pathways for four selected chronic diseases. Secondly, using quantitative data covering a population of 214,700 to validate and test hypothesis derived from the qualitative findings...
April 12, 2018: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/29644921/cognitive-frailty-and-its-association-with-all-cause-mortality-among-community-dwelling-older-adults-in-taiwan-results-from-i-lan-longitudinal-aging-study
#12
Li-Kuo Liu, Wei-Ju Lee, Yi-Hui Wu, An-Chun Hwang, Ming-Hsien Lin, Hiroyuki Shimada, Li-Ning Peng, Ching-Hui Loh, Hidenori Arai, Liang-Kung Chen
BACKGROUND: The definition of cognitive frailty and its prediction for adverse outcome of community-living older adults remains controversial. This study aims to evaluate the association between cognitive frailty and all-cause mortality among community-living older adults. METHODS: Data of the I-Lan Longitudinal Aging Study (ILAS) were retrieved for study. Frailty was defined by Fried's criteria, and a series of neuropsychological assessments, including the Mini-Mental State Examination (MMSE), Center for Epidemiology Studies-Depression (CES-D), the delay free recall in the Chinese Version Verbal Learning Test, the Boston Naming Test, the category (animal) Verbal Fluency Test, the Taylor Complex Figure Test, the digital backward and the Clock Drawing Test were performed...
April 12, 2018: Rejuvenation Research
https://www.readbyqxmd.com/read/29643153/incidence-rate-of-community-acquired-pneumonia-in-adults-a-population-based-prospective-active-surveillance-study-in-three-cities-in-south-america
#13
Gustavo Daniel Lopardo, Diego Fridman, Enrique Raimondo, Henry Albornoz, Ana Lopardo, Homero Bagnulo, Daniel Goleniuk, Manuelita Sanabria, Daniel Stamboulian
OBJECTIVE: To determine the incidence rate and mortality of community-acquired pneumonia (CAP) in adults in three cities in Latin America during a 3-year period. DESIGN: Prospective population-based surveillance study. SETTING: Healthcare facilities (outpatient centres and hospitals) in the cities of General Roca (Argentina), Rivera (Uruguay) and Concepción (Paraguay). PARTICIPANTS: 2302 adults aged 18 years and older with CAP were prospectively enrolled between January 2012 and March 2015...
April 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29627405/prevalence-and-correlates-of-binge-drinking-among-older-adults-with-multimorbidity
#14
Benjamin H Han, Alison A Moore, Scott E Sherman, Joseph J Palamar
BACKGROUND: Binge drinking among older adults has increased in the past decade. Binge drinking is associated with unintentional injuries, medical conditions, and lower health-related quality of life. No studies have characterized multimorbidity among older binge drinkers. METHODS: We examined past 30-day binge alcohol use and lifetime medical conditions among adults age ≥50 from the National Survey on Drug Use and Health from 2005 to 2014. Self-reported lifetime prevalence of 13 medical conditions and medical multimorbidity (≥2 diseases) among binge drinkers were compared to non-binge drinkers...
March 31, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29626050/impact-of-multimorbidity-count-on-all-cause-mortality-and-glycaemic-outcomes-in-people-with-type-2-diabetes-a-systematic-review-protocol
#15
Jason I Chiang, John Furler, Frances S Mair, Bhautesh Jani, Barbara I Nicholl, Alicia Jenkins, Patrick Condron, David O'Neal, Jo-Anne Manski-Nankervis
INTRODUCTION: Type 2 diabetes (T2D) is a leading health priority worldwide. Multimorbidity (MM) is a term describing the co-occurrence of two or more chronic diseases or conditions. The majority of people living with T2D have MM. The relationship between MM and mortality and glycaemia in people with T2D is not clear. METHODS AND ANALYSIS: Medline, Embase, Cumulative Index of Nursing and Allied Health Complete, The Cochrane Library, and SCOPUS will be searched with a prespecified search strategy...
April 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29621856/minimally-disruptive-medicine
#16
Lyndal Trevena
BACKGROUND: Patients with complex multimorbidity often experience a substantial burden because of the treatments they receive as well as the burden of their chronic health problems. There has been increasing recognition of this issue, particularly in the UK and US. OBJECTIVE: This article summarises the evolution of the concept ‘minimally disruptive medicine’ for patients with complex multimorbidity. It outlines some of the factors that should be considered in assessing both the burden of treatment and a patient’s capacity to cope with this workload...
April 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29621854/street-health-service
#17
Diane Arnold-Reed, Lakkhina Troeung, Tom Brett, Wendy Chan She Ping-Delfos, Cecily Strange, Elizabeth Geelhoed, Colleen Fisher, David Preen
Street-based general practice services are critical to facilitate easy access to primary and secondary management of chronic multimorbid conditions in marginalised (especially Aboriginal) patients.
April 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29614531/-deceleration-an-important-first-step-in-caring-for-multimorbid-patients
#18
Cornel Sieber
No abstract text is available yet for this article.
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29608779/interdisciplinary-home-visits-for-individuals-with-advanced-parkinson-s-disease-and-related-disorders
#19
Jori Fleisher, William Barbosa, Meghan M Sweeney, Sarah E Oyler, Amy C Lemen, Arash Fazl, Mia Ko, Talia Meisel, Naomi Friede, Geraldine Dacpano, Rebecca M Gilbert, Alessandro Di Rocco, Joshua Chodosh
Parkinson's disease (PD) is a complex, multisymptom, neurodegenerative disease affecting primarily older adults. With progression, many individuals become homebound and removed from coordinated, expert care, resulting in excess morbidity, mortality, and healthcare expenditures in acute care settings and institutions. Home visit care models have achieved the triple aim of improving individual and population health while reducing costs in many frail, community-dwelling geriatric cohorts. This study details a novel, interdisciplinary home visit program specifically designed for individuals with PD and related disorders and their family caregivers built upon best practice principles in the care of multimorbid older adults...
April 2, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29608126/gender-differences-in-the-prevalence-of-fibromyalgia-and-in-concomitant-medical-and-psychiatric-disorders-a-national-veterans-health-administration-study
#20
Caroline A Arout, Mehmet Sofuoglu, Lori A Bastian, Robert A Rosenheck
BACKGROUND: Fibromyalgia is a poorly understood, chronically disabling pain syndrome. While research has focused on its clinical presentation and treatment, less is known about fibromyalgia's clinical epidemiology in real-world healthcare systems. Gender differences have been difficult to study because relatively few males are diagnosed with fibromyalgia. METHODS: Veterans Health Administration (VHA) patients diagnosed with fibromyalgia nationwide in FY 2012 were compared to Veterans with other pain diagnoses on sociodemographic characteristics, medical and psychiatric diagnoses, health service use, and opioid and psychotropic prescription fills...
April 2, 2018: Journal of Women's Health
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