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Granuloma annulare

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https://www.readbyqxmd.com/read/28438438/-multiple-cephalic-deep-granuloma-annulare-of-children
#1
A Bulinckx, N Cambier, L Wayllace Gaspar, I Théate, P P Roquet-Gravy, D Bessis
BACKGROUND: Deep granuloma annulare is a fairly rare variety of granuloma annulare. It is seen predominantly in children and mainly affects the anterior aspect of the legs and the top of the feet; cephalic presentation is rare. Below, we report three cases of deep granuloma annulare in children presenting solely at the cephalic extremity. PATIENTS AND METHODS: Case 1: a six-year-old boy presented 7 cutaneous nodules measuring 1 to 2cm that were flesh-coloured, insensitive to palpation, of hard consistency and deeply attached...
April 21, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28419540/deep-granuloma-annulare-mimicking-inflamed-cysts-in-a-teenager
#2
Emily L Guo, Catherine A Degesys, Richard Jahan-Tigh, Audrey Chan
We describe deep granuloma annulare (DGA) of the forehead mimicking inflamed cysts. Reactive inflammation and sterile purulent drainage may be an underrecognized feature of DGA.
April 17, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28374407/cutaneous-manifestations-of-diabetes-mellitus-a-review
#3
REVIEW
Ana Luiza Lima, Tanja Illing, Sibylle Schliemann, Peter Elsner
Diabetes mellitus is a widespread endocrine disease with severe impact on health systems worldwide. Increased serum glucose causes damage to a wide range of cell types, including endothelial cells, neurons, and renal cells, but also keratinocytes and fibroblasts. Skin disorders can be found in about one third of all people with diabetes and frequently occur before the diagnosis, thus playing an important role in the initial recognition of underlying disease. Noninfectious as well as infectious diseases have been described as dermatologic manifestations of diabetes mellitus...
April 3, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28328616/borderline-tuberculoid-leprosy-masquerading-as-granuloma-annulare-a-clinical-and-histological-pitfall
#4
Tian Hao Zhu, Faranak Kamangar, Marc Silverstein, Maxwell A Fung
INTRODUCTION: Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae, an intracellular acid-fast bacillus that tends to infect the skin and peripheral nerves. Because of the wide array of cutaneous manifestation, diagnosis is not always straightforward, especially in nonendemic regions of the world such as the United States. CASE REPORT: The authors report an unusual case of borderline tuberculoid leprosy in an 80-year-old white woman from California...
April 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28326206/chronic-hepatitis-with-liver-granulomas-in-a-patient-with-granuloma-annulare-a-case-report-and-review-of-the-literature
#5
Majid Alsahafi, Mohammed I AlJasser, Sunil Kalia, H M Yang, Alnoor Ramji
Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28325398/antimalarial-therapy-for-granuloma-annulare-results-of-a-retrospective-analysis
#6
Sungat K Grewal, Courtney Rubin, Misha Rosenbach
No abstract text is available yet for this article.
April 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28300860/annular-elastolytic-giant-cell-granuloma-successfully-treated-with-adalimumab-subsequently-complicated-by-drug-induced-lupus
#7
Adele Haimovic, Hideko Kamino, David E Cohen
We report a 51-year-old female with a 3-year history of recalcitrant annular elastolytic giant cell granuloma (AEGCG) who was effectively treated with the anti-tumor necrosis factor (TNF)-alpha antibody, adalimumab. Her disease was refractory to topical glucocorticoids, intralesional glucocorticoids, narrow-band ultraviolet light (UV)-B phototherapy and cyclosporine. During her treatment with adalimumab she developed a positive anti-nuclear-antibody and double-stranded-DNA antibody and her treatment was terminated...
February 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28244938/actinic-granuloma-annulare-with-scarring-and-open-comedones
#8
Cfb Gavioli, Nys Valente, M Sangueza, M M Nico
Actinic granuloma and annular elastolytic giant cell granuloma are variants of granuloma annulare affecting, respectively, sun-exposed and sun-covered skin sites on where, besides classical findings, abundant elastophagocytosis is observed. Here, we report a case of exuberant actinic granuloma annulare that, in addition to extensive scarring, showed multiple overlying open comedones. Markedly dilated follicular infundibula filled with compact masses of laminated keratinous material were observed in proximity to dermal inflammation composed of many histiocytes and multinucleated giant cells in close association with degenerated elastic fibers and abundant elastophagocytosis...
February 14, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28239844/spectrum-and-clinical-variants-of-giant-cell-elastolytic-granuloma
#9
Wan-Ting Chen, Pa-Fan Hsiao, Yu-Hung Wu
BACKGROUND: Giant cell elastolytic granuloma, also known as annular elastolytic giant cell granuloma or actinic granuloma, is histologically characterized by elastophagocytosis. Recent studies have revealed various clinical presentations in both sun-exposed and non-sun-exposed areas. OBJECTIVES: To clarify clinical characteristics based on case series observation. METHODS: We retrospectively reviewed patients who fulfilled the pathological diagnosis criteria for giant cell elastolytic granuloma seen at Mackay Memorial Hospital from 2000 to 2014...
February 27, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28225950/diabetes-mellitus-and-the-skin
#10
Adriana Lucia Mendes, Helio Amante Miot, Vidal Haddad
Several dermatoses are routinely associated with diabetes mellitus, especially in patients with chronic disease. This relationship can be easily proven in some skin disorders, but it is not so clear in others. Dermatoses such necrobiosis lipoidica, granuloma annulare, acanthosis nigricans and others are discussed in this text, with an emphasis on proven link with the diabetes or not, disease identification and treatment strategy used to control those dermatoses and diabetes.
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28166622/granuloma-annulare-a-case-treated-with-infliximab-successfully
#11
Alessandro Giunta, Andrea Chiricozzi, Maria V Cannizzaro, Annunziata Dattola, Manuela Ruzzetti, Steven P Nisticò, Sergio Chimenti
No abstract text is available yet for this article.
April 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28139140/canalicular-lacerations-factors-predicting-outcome-at-a-tertiary-eye-care-centre
#12
Swati Singh, Anasua Ganguly, Apurva Hardas, Devjyoti Tripathy, Suryasnata Rath
To determine the factors predictive of outcome in canalicular laceration repair at a tertiary eye care centre. A retrospective review of the medical records of all primary canalicular laceration repairs managed at a tertiary eye care centre between the years 2006 and 2014 was done. Thirty-nine patients were included and majority were male (79.5%) with a mean age of 30.05 + 16.2 years (range 2-65). Most (n = 34) had monocanalicular laceration and 5 had bicanalicular laceration. All surgeries were done in the operating room setting...
February 2017: Orbit
https://www.readbyqxmd.com/read/28116823/annular-lesions-of-cutaneous-sarcoidosis-with-granulomatous-vasculitis
#13
Kana Mizuno, Chuyen Thi Hong Nguyen, Ikuko Ueda-Hayakawa, Hiroyuki Okamoto
Sarcoidosis is known to be involved in diseases with vasculitis as sarcoid vasculitis. However, vasculitis in cutaneous sarcoidal lesions is extremely rare. Here we describe a case of sarcoidosis with multiple annular skin lesions with granulomatous vasculitis. A 62-year-old female was diagnosed with sarcoidosis by chest-abdominal computed tomographic examination and laboratory tests. The skin lesions had appeared on her lower limbs 2 years before. Physical examination showed multiple infiltrated annular eruptions on the lower extremities...
January 24, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28099955/dermoscopy-of-granuloma-annulare-a-clinical-and-histological-correlation-study
#14
Enzo Errichetti, Aimilios Lallas, Zoe Apalla, Alessandro Di Stefani, Giuseppe Stinco
BACKGROUND: Dermoscopy of granuloma annulare has been investigated by several studies, but none of them took into account the variability of dermoscopic findings according to clinical characteristics and/or histological subtype. OBJECTIVE: To describe the dermoscopic features of classic granuloma annulare and seek possible dermoscopic clues related to specific clinical findings/histological subpatterns. METHODS: A representative dermoscopic image of a target lesion (the most active lesion underwent histological examination) was retrospectively assessed for the presence of specific morphological findings, correlating them with clinical variables, i...
January 19, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28095713/disseminated-eruptive-granuloma-annulare-induced-by-levetiracetam
#15
Betul Sereflican, Tekden Karapinar, Selma Erdogan Duzcu, Şule Aydin Turkoglu
Granuloma annulare (GA) is a benign, granulomatous cutaneous disease without clear etiology. Disseminated and drug induced granuloma annulare is a rare presentation. We present a 47-year-old woman with diffuse circular erythematous eruptions following treatment with levetiracetam. Her clinical and histopathological findings were compatible with the diagnosis of granuloma annulare. To the best of our knowledge, there is no previous report of this skin disease as a result of levetiracetam use. We report this case to highlight this antiepileptic drug as a possible etiologic agent in disseminated granuloma annulare...
January 17, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28094163/granulomatous-histiocytic-dermatitides
#16
Mark R Wick
Granulomas of the skin may be classified in several ways. They are either infectious or non-infectious in character, and they contain areas of necrobiosis or necrosis, or not. Responsible infectious agents may be mycobacterial, fungal, treponemal, or parasitic organisms, and each case of granulomatous dermatitis should be assessed histochemically for those microbes. In the non-infectious group, examples of necrobiotic or necrotizing granulomas include granuloma annulare; necrobiosis lipoidica; rheumatoid nodule; and lupus miliaris disseminates faciei...
December 14, 2016: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/28070647/-two-children-with-intermediate-uveitis-and-granuloma-annulare-from-the-same-neighbourhood
#17
A Nessmann, R Klein, P Herzer, M Zierhut
Two children from the same neighbourhood presented with concomitant granuloma annulare (GA) and intermediate uveitis (IU) at an interval of 2 weeks. A coincidence seemed unlikely, as IU is very rare in children and even more so in connection with GA. Thorough diagnosis was performed to exclude other associated diseases. No systemic disease, no special features of vaccination or medication, no history of infection, and no toxic cause could be found. An association between GA and IU based on other, as yet undiagnosed factors, is still possible...
January 9, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28033153/palisaded-granuloma-on-the-nose-an-atypical-presentation-of-granuloma-annulare
#18
Amílcar G Rodríguez, Jorge L Sánchez, Julio E Sánchez
Granuloma annulare (GA) is a common, asymptomatic dermatosis of unknown etiology. Many variants exist, among them widespread papules, papules in photodistribution, papules marked by tiny crusts ("perforating" GA), patches, plaques, and nodules (subcutaneous GA). The histopathological hallmark is a palisaded histiocytic infiltrate surrounding a central area of degenerated collagen with abundant mucin deposits. We report 2 women who presented with persistent nodules on the nose, which, on histopathological examination, showed a palisaded granuloma...
February 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28007053/specific-skin-signs-as-a-cutaneous-marker-of-diabetes-mellitus-and-the-prediabetic-state-a-systematic-review
#19
REVIEW
Rewend Salman Bustan, Daanyaal Wasim, Knud Bonnet Yderstræde, Anette Bygum
INTRODUCTION: Diabetes mellitus and the prediabetic state are associated with a number of skin manifestations. This study is a systematic review of the following manifestations: acanthosis nigricans (AN), skin tags (ST), diabetic dermopathy (DD), rubeosis faciei (RF), pruritus (PR), granuloma annulare (GA), necrobiosis lipoidica (NL), scleroedema diabeticorum (SD) and bullosis diabeticorum (BD). These conditions possibly relate to underlying diabetogenic mechanisms. Our aim was to determine whether skin signs are feasible as cutaneous markers for the prediabetic or diabetic state...
January 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/27891439/o-brien-s-granuloma-a-case-report
#20
Pratik Mukesh Thacker, Kashinath Nayak, Flora Dorothy Lobo, Pavithra Govindasamy
Actinic granuloma is a self-limiting chronic disorder with elastolytic granulomas, mainly of the sun exposed skin and unknown pathogenesis. We report a case of a middle aged woman with multiple annular erythematous lesions. Histopathology revealed degenerated elastic fibres with histiocyte aggregates surrounded by multiple giant cells suggestive of elastolytic granulomas. She also had associated dyslipidemia and hypothyroidism. Actinic granuloma is relatively rare in the Indian population and needs to be differentiated from conditions like sarcoidosis and granuloma annulare...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
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