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Allergic contact dermatitis

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https://www.readbyqxmd.com/read/28444762/screening-allergic-reactions-to-resol-resin-based-on-phenol-and-formaldehyde-in-a-clinic-of-occupational-dermatology
#1
Kristiina Aalto-Korte, Katri Suuronen
BACKGROUND: Allergic reactions to resol-type phenol formaldehyde resin [phenol formaldehyde resin 2 (PFR2)] are relatively common. It has been suggested that PFR2 should be included in baseline series. However, a recent international study found clinical relevance in only 25% of patients. OBJECTIVES: To report the results of screening with PFR2 over a 5-year period (2012-2016), and to study the clinical relevance of allergic reactions to PFR2 over a 15-year period (2002-2016)...
April 25, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28440548/contact-sensitizers-trigger-human-cd1-autoreactive-t-cell-responses
#2
Richard J Betts, Adrijana Perkovic, Subhashree Mahapatra, Aurélia Del Bufalo, Kaddy Camara, Amy R Howell, Silvia Martinozzi Teissier, Gennaro De Libero, Lucia Mori
Allergic contact dermatitis is a primarily T-cell-mediated inflammatory skin disease induced by exposure to small molecular-weight haptens, which covalently bind to proteins. The abundance of cutaneous T cells that recognize CD1a antigen-presenting molecules raises the possibility that MHC-independent antigen presentation may be relevant in some hapten-driven immune responses. Here we examine the ability of contact sensitizers to influence CD1-restricted immunity. Exposure of human antigen-presenting cells such as monocyte-derived dendritic cells and THP-1 cells to the prototypical contact sensitizer dinitrochlorobenzene potentiated the response of CD1a- and CD1d-autoreactive T cells, which released a vast array of cytokines in a CD1- and TCR-dependent manner...
April 25, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/28425131/garlic-dermatitis-on-the-neck-of-an-infant-treated-for-nasal-congestion
#3
Amin Esfahani, Sarah L Chamlin
The health benefits of garlic (Allium sativum) as a naturopathic remedy have been well documented, but topical application of garlic has been linked to allergic and irritant contact dermatitis. We present a case of severe irritant contact dermatitis due to application of a fresh garlic necklace to the neck of infant for treatment of nasal congestion.
April 19, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28425114/a-multi-institutional-joint-study-of-contact-dermatitis-related-to-hair-colouring-and-perming-agents-in-japan
#4
Akiko Ito, Kazue Nishioka, Hiromi Kanto, Akiko Yagami, Shigeki Yamada, Mariko Sugiura, Chihiro Yasunaga, Keiko Yoshii, Hiromi Kobayashi, Atsuko Adachi, Yuko Ikezawa, Kumiko Washizaki, Shigeki Inui, Hitoshi Miyazawa, Naoki Oiso, Tokio Nakata, Kayoko Matsunaga
BACKGROUND: In Japan, allergic contact dermatitis caused by hair colouring agents is a considerable problem for those occupationally exposed and also for consumers. Over the last 20 years, p-phenylenediamine (PPD) has been a common allergen, with ∼7% positive patch test reactions. OBJECTIVES: To investigate which ingredients caused allergic contact dermatitis related to hair dye and perming solutions in Japan, to assess whether PPD is suitable for screening for hair dye allergy, and to propose allergens for a Japanese hairdresser series...
April 20, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28421670/an-epidemic-of-allergic-contact-dermatitis-caused-by-a-new-allergen-caprylhydroxamic-acid-in-moisturizers
#5
Leena Ackermann, Hannele Virtanen, Laura Korhonen, Arja Laukkanen, Laura Huilaja, Riitta Riekki, Taina Hasan
BACKGROUND: In 2016, dermatologists in Finland suspected contact allergy in several patients using moisturizers under the trade name Apobase®. Following a formulation change, Phenostat™, which is a mixture of phenoxyethanol, caprylhydroxamic acid, and methylpropanediol, was used as a preservative in Apobase® moisturizers in Finland. OBJECTIVES: To confirm the suspected contact allergy to Apobase® cream, oily cream, and/or lotion, and to identify the specific contact allergen and define its optimal patch test concentration...
April 19, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28420251/differential-diagnosis-of-diaper-dermatitis
#6
Bernard Cohen
Mild diaper dermatitis often occurs in children before toilet training is complete, particularly from 9 to 12 months of age, and the most common presentation is an irritant contact dermatitis. Diaper dermatitis may account for up to 25% of dermatology visits to health care providers during the first year of life. Fortunately, since the introduction of hypoallergenic, superabsorbent modern disposable diapers, the incidence and severity of irritant and allergic contact dermatitis has decreased dramatically. Diaper dermatitis broadly refers to skin disorders that occur in the diaper area, such as skin eruptions triggered by diapers, rashes exacerbated by the diaper, and other events that occur in the diaper area...
May 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28420106/temporary-black-henna-tattoos-and-sensitization-to-para-phenylenediamine-ppd-two-paediatric-case-reports-and-a-review-of-the-literature
#7
Elisa Panfili, Susanna Esposito, Giuseppe Di Cara
Background: The use of temporary henna tattoos has increased dramatically in recent years, especially in children and adolescents. To obtain a darker colour and prolong the life of the tattoo, red henna, a plant-derived substance, is typically added to para-phenylenediamine (PPD). The mixture is called temporary black henna tattoo (TBHT). Because of its molecular characteristics, PPD can induce skin sensitization that may cause various clinical manifestations with successive exposures, among which the most common is allergic contact dermatitis (ACD)...
April 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28416298/-epicutaneous-patch-testing-in-delayed-drug-hypersensitivity-reactions-induced-by-antiepileptic-drugs
#8
Lobna Ben Mahmoud, Najla Bahloul, Hanen Ghozzi, Brahim Kammoun, Ahmed Hakim, Zouheir Sahnoun, Sami Kammoun, Khaled Zeghal
INTRODUCTION: Antiepileptic drugs are widely used and are associated with numerous side effects including skin eruptions. Epicutaneous tests have been used with variable success in skin drug reactions. The purpose of this study was to evaluate the profitability of epicutaneous tests in delayed hypersensitivity reactions induced by antiepileptic drugs. METHODS: We analyzed all cases of allergic skin reactions to antiepileptic drugs notified in regional pharmacovigilance center of Sfax (Tunisia) between June 1, 2014 and April 30, 2016...
March 25, 2017: Thérapie
https://www.readbyqxmd.com/read/28411766/a-review-of-the-impact-of-patch-testing-on-quality-of-life-in-allergic-contact-dermatitis
#9
Faustine Ramirez, Mary-Margaret Chren, Nina Botto
No abstract text is available yet for this article.
May 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28401489/chemokine-receptor-cxcr3-in-the-spinal-cord-contributes-to-chronic-itch-in-mice
#10
Peng-Bo Jing, De-Li Cao, Si-Si Li, Meixuan Zhu, Xue-Qiang Bai, Xiao-Bo Wu, Yong-Jing Gao
Recent studies have shown that the chemokine receptor CXCR3 and its ligand CXCL10 in the dorsal root ganglion mediate itch in experimental allergic contact dermatitis (ACD). CXCR3 in the spinal cord also contributes to the maintenance of neuropathic pain. However, whether spinal CXCR3 is involved in acute or chronic itch remains unclear. Here, we report that Cxcr3 (-/-) mice showed normal scratching in acute itch models but reduced scratching in chronic itch models of dry skin and ACD. In contrast, both formalin-induced acute pain and complete Freund's adjuvant-induced chronic inflammatory pain were reduced in Cxcr3 (-/-) mice...
April 11, 2017: Neuroscience Bulletin
https://www.readbyqxmd.com/read/28401153/metals-are-important-contact-sensitizers-an-experience-from-lithuania
#11
Kotryna Linauskienė, Laura Malinauskienė, Audra Blažienė
Background. Metals are very frequent sensitizers causing contact allergy and allergic contact dermatitis worldwide; up-to-date data based on patch test results has proved useful for the identification of a problem. Objectives. In this retrospective study prevalence of contact allergy to metals (nickel, chromium, palladium, gold, cobalt, and titanium) in Lithuania is analysed. Patients/Methods. Clinical and patch test data of 546 patients patch tested in 2014-2016, in Vilnius University Hospital Santariskiu Klinikos, was analysed and compared with previously published data...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28396898/-allergic-contact-dermatitis-of-the-scalp
#12
REVIEW
L Koch, W Aberer
Contact allergy represents an important differential diagnosis to other skin diseases of the scalp. The typical efflorescences, spreading in the periphery, pruritus, and the clinical history support the differential diagnosis. Since the scalp is particularly resistant to contact dermatitis, allergens applied to this area often produce dermatitis of the eyelids, ears and neck. Nevertheless, potent allergens such as para-phenylendiamine can also cause severe reactions of the scalp. The most important allergens eliciting contact allergy of the scalp are found in bleaches and dyes, shampoos and conditioners, products for perm waves and straighteners as well as topical drugs...
April 10, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28396866/survey-of-occupational-allergic-contact-dermatitis-and-patch-test-among-clothing-employees-in-beijing
#13
Yu-Xin Chen, Bing-Ai Gao, Hai-Yan Cheng, Lin-Feng Li
Occupational population-based epidemiological data relating to occupational contact allergies in the Chinese clothing industry are limited. To investigate the prevalence of occupational allergic contact dermatitis (OACD) and to identify the causative allergens among clothing employees in China, a cross-sectional study was conducted in 529 clothing employees at 12 clothing factories in Beijing. All employees were subjected to an interview using self-administered questionnaire and skin examination, and those who were diagnosed with occupational contact dermatitis (OCD) were patch tested...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28396114/surgery-related-contact-dermatitis-a-review-of-potential-irritants-and-allergens
#14
Kevin A Cook, John M Kelso
Surgical procedures utilize an increasing number of medical products including antiseptics, anesthetics, gloves, suture materials, tissue adhesives, topical antibiotics, and bandages. Many of these products have irritant potential. Allergic contact dermatitis has also been reported. This review covers preoperative, operative, and postoperative exposures that may result in contact dermatitis. Testing with standard patch panels such as T.R.U.E. Test and the North American Contact Dermatitis Group 65 allergen series does not evaluate for all relevant contactants...
April 7, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28394773/occupational-contact-dermatitis-in-north-american-production-workers-referred-for-patch-testing-retrospective-analysis-of-cross-sectional-data-from-the-north-american-contact-dermatitis-group-1998-to-2014
#15
Erin M Warshaw, Solveig L Hagen, Joel G DeKoven, Kathryn A Zug, Denis Sasseville, Donald V Belsito, Matthew J Zirwas, Joseph F Fowler, James S Taylor, Anthony F Fransway, Vincent A DeLeo, James G Marks, Melanie D Pratt, Howard I Maibach, C G Toby Mathias
BACKGROUND: Little is known about the epidemiology of contact dermatitis in production workers (PWs). OBJECTIVE: The aims of this study were to estimate the prevalence of contact dermatitis and characterize clinically relevant and occupationally related allergens among North American PWs undergoing patch testing. METHODS: This was a retrospective cross-sectional analysis of North American Contact Dermatitis Group data from 1998 to 2014. RESULTS: Of 39,332 patch-tested patients, 2732 (7...
April 7, 2017: Dermatitis
https://www.readbyqxmd.com/read/28392290/association-between-atopic-dermatitis-and-contact-sensitization-a-systematic-review-and-meta-analysis
#16
Carsten R Hamann, Dathan Hamann, Alexander Egeberg, Jeanne D Johansen, Jonathan Silverberg, Jacob P Thyssen
BACKGROUND: It is unclear whether patients with atopic dermatitis (AD) have an altered prevalence or risk for contact sensitization. Increased exposure to chemicals in topical products together with impaired skin barrier function suggest a higher risk, whereas the immune profile suggests a lower risk. OBJECTIVE: To perform a systematic review and meta-analysis of the association between AD and contact sensitization. METHODS: The PubMed/Medline, Embase, and Cochrane databases were searched for articles that reported on contact sensitization in individuals with and without AD...
April 6, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28386993/nickel-allergy-in-a-danish-population-25%C3%A2-years-after-the-first-nickel-regulation
#17
Malin G Ahlström, Torkil Menné, Jacob P Thyssen, Jeanne D Johansen
BACKGROUND: Nickel in metallic items has been regulated in Denmark since 1990; however, 10% of young Danish women are still sensitized to nickel. There is a need for continuous surveillance of the effect of regulation. OBJECTIVES: To identify current self-reported metallic exposures leading to dermatitis in nickel-allergic patients, and the minimum contact time needed for dermatitis to occur. METHODS: A questionnaire was sent to all patients who reacted positively to nickel sulfate 5% pet...
April 7, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28386982/a-putative-case-of-allergic-contact-dermatitis-caused-by-a-jagua-tattoo
#18
Julie Waton, Fanny Brault, Elisabeth Laveine
No abstract text is available yet for this article.
May 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28386980/allergic-contact-dermatitis-in-two-employees-of-an-ethylene-amine-producing-factory
#19
Daan Dittmar, Klaziena Politiek, Pieter-Jan Coenraads, Peter A Flach, Marie L Schuttelaar
No abstract text is available yet for this article.
May 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28382616/stratum-corneum-profiles-of-inflammatory-mediators-in-patch-test-reactions-to-common-contact-allergens-and-sodium-lauryl-sulfate
#20
S A Koppes, S Ljubojevic Hadzavdic, I Jakasa, N Franceschi, R Jurakić Tončić, B Marinović, R Brans, S Gibbs, M H W Frings-Dresen, T Rustemeyer, S Kezic
BACKGROUND: Recent studies have demonstrated allergen-specific differences in the gene expression of inflammatory mediators in patch tested skin. OBJECTIVES: To determine levels of various inflammatory mediators in the stratum corneum (SC) after patch testing with common contact allergens and the skin irritant sodium lauryl sulfate (SLS). METHODS: In total, 27 individuals who had previously patch tested positive to nickel, chromium, methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) or para-phenylenediamine were retested and then patch tested with SLS and petrolatum, with petrolatum serving as the patch test control...
November 4, 2016: British Journal of Dermatology
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