keyword
MENU ▼
Read by QxMD icon Read
search

Neurosurgery

keyword
https://www.readbyqxmd.com/read/28099855/primary-cell-culture-of-live-neurosurgically-resected-aged-adult-human-brain-cells-and-single-cell-transcriptomics
#1
Jennifer M Spaethling, Young-Ji Na, Jaehee Lee, Alexandra V Ulyanova, Gordon H Baltuch, Thomas J Bell, Steven Brem, H Isaac Chen, Hannah Dueck, Stephen A Fisher, Marcela P Garcia, Mugdha Khaladkar, David K Kung, Timothy H Lucas, Donald M O'Rourke, Derek Stefanik, Jinhui Wang, John A Wolf, Tamas Bartfai, M Sean Grady, Jai-Yoon Sul, Junhyong Kim, James H Eberwine
Investigation of human CNS disease and drug effects has been hampered by the lack of a system that enables single-cell analysis of live adult patient brain cells. We developed a culturing system, based on a papain-aided procedure, for resected adult human brain tissue removed during neurosurgery. We performed single-cell transcriptomics on over 300 cells, permitting identification of oligodendrocytes, microglia, neurons, endothelial cells, and astrocytes after 3 weeks in culture. Using deep sequencing, we detected over 12,000 expressed genes, including hundreds of cell-type-enriched mRNAs, lncRNAs and pri-miRNAs...
January 17, 2017: Cell Reports
https://www.readbyqxmd.com/read/28098060/gripping-forceps-double-action-for-micro-neurosurgery
#2
V Wierzbicki, A Pesce, R Caruso
Gripping forceps "double action" for microneurosurgery.
September 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28097621/practice-patterns-of-venous-thromboembolism-prophylaxis-in-underweight-critically-ill-patients-with-neurologic-injury
#3
Kevin Betthauser, Hannah Pope, Mollie Gowan, Theresa Human
PURPOSE: Venous thromboembolism (VTE) prophylaxis in underweight patients with neurologic injury remains unaddressed by guidelines and primary literature. This study aimed to describe VTE prophylaxis strategies employed in this population and compare the impact of underweight and non-obese patients on thrombotic and bleeding events. METHODS: A retrospective review of adults admitted with a diagnosis of neurologic injury to a neurology/neurosurgery intensive care unit (ICU) over 6 years...
January 17, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28094427/minimalism-in-art-medical-science-and-neurosurgery
#4
Ali İhsan Ökten
The word ''minimalism'' is a word derived from French the word ''minimum''. Whereas the lexical meaning of minimum is ''the least or the smallest quantity necessary for something'', its expression in mathematics can be described as ''the lowest step a variable number can descend, least, minimal''. Minimalism, which advocates an extreme simplicity of the artistic form, is a current in modern art and music whose origins go to 1960s and which features simplicity and objectivity. Although art, science and philosophy are different disciplines, they support each other from time to time, sometimes they intertwine and sometimes they copy each other...
December 21, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28092933/estimation-of-the-size-of-the-iatrogenic-creutzfeldt-jakob-disease-outbreak-associated-with-cadaveric-dura-mater-grafts-in-korea
#5
Byoug-Hak Jeon, Jinseob Kim, GangHyun Kim Kim, Soo Chul Park, SangYun Kim, Hae-Kwan Cheong
Purpose: This study estimated the overall magnitude of Creutzfeldt-Jakob disease (iCJD) based on dura graft cases in Korea using a mathematical model. Methods: We estimated the number of annual cases of dura grafts performed between 1980 and 1995 by applying the proportion of dura grafts recorded by the Health Insurance Review Agency claim dataset in Korea to the number of nationwide neurosurgery cases. The distribution of the incubation period was assumed to fall under a Weibull distribution with density function or a log-logistic distribution with density function...
December 19, 2016: Epidemiology and Health
https://www.readbyqxmd.com/read/28092908/2016-biennial-meeting-of-the-american-society-for-stereotactic-and-functional-neurosurgery-chicago-il-usa-june-18-21-2016-abstracts
#6
(no author information available yet)
No abstract text is available yet for this article.
2016: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28092106/a-randomised-controlled-trial-examining-the-effect-of-acupuncture-at-the-ex-hn3-yintang-point-on-pre-operative-anxiety-levels-in-neurosurgical-patients
#7
M D Wiles, J Mamdani, M Pullman, J C Andrzejowski
Pre-operative anxiety is an unpleasant state of psychological distress that occurs in up to 87% of patients awaiting neurosurgical procedures. Sedative medication is undesirable in this population due to the need for early postoperative neurological assessment. Acupuncture has previously been shown to reduce pre-operative anxiety, but studies involving neurosurgical patients are lacking. This single-centre, prospective, randomised controlled trial was designed to determine the effect of acupuncture at the EX-HN3 (Yintang point) on pre-operative anxiety levels in neurosurgical patients...
January 16, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28087556/ahead-study-an-observational-study-of-the-management-of-anticoagulated-patients-who-suffer-head-injury
#8
Suzanne Mason, Maxine Kuczawski, M Dawn Teare, Matt Stevenson, Steve Goodacre, Shammi Ramlakhan, Francis Morris, Joanne Rothwell
OBJECTIVES: Management of anticoagulated patients after head injury is unclear due to lack of robust evidence. This study aimed to determine the adverse outcome rate in these patients and identify risk factors associated with poor outcome. DESIGN: Multicentre, observational study using routine patient records. SETTING: 33 emergency departments in England and Scotland. PARTICIPANTS: 3566 adults (aged ≥16 years) who had suffered blunt head injury and were currently taking warfarin...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28084999/otogenic-intracranial-abscesses-our-experience-over-the-last-four-decades
#9
Anu Laulajainen Hongisto, Antti A Aarnisalo, Laura Lempinen, Riste Saat, Antti Markkola, Kimmo Leskinen, Göran Blomstedt, Jussi Jero
OBJECTIVE: To evaluate the predisposing factors for otogenic intracranial abscesses, assess their changes over time, and analyze how they differ from those due to other causes. MATERIALS AND METHODS: The medical records of all patients treated for otogenic intracranial abscesses, between 1970 and 2012 at a tertiary referral center, were retrospectively analyzed. The analysis included patient demographics, clinical characteristics, causative pathogens, treatments, outcomes, and comparisons of otogenic and non-otogenic intracranial abscesses...
January 13, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28084907/academic-impact-and-rankings-of-neuroendovascular-fellowship-programs-across-the-united-states
#10
Ashish Sonig, Hussain Shallwani, Bennett R Levy, Hakeem J Shakir, Adnan H Siddiqui
OBJECTIVE Publication has become a major criterion of success in the competitive academic environment of neurosurgery. This is the first study that has used departmental h index-and e index-based matrices to assess the academic output of neuroendovascular, neurointerventional, and interventional radiology fellowship programs across the continental US. METHODS Fellowship program listings were identified from academic and organization websites. Details for 37 programs were available. Bibliometric data for these programs were gathered from the Thomson Reuters Web of Science database...
January 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28084258/history-of-neurosurgery-at-postgraduate-institute-of-medical-education-and-research-chandigarh
#11
Sunil K Gupta, Kanchan K Mukherjee, Rajesh Chhabra, Manjul Tripathi
The Department of Neurosurgery started functioning at the Postgraduate Institute of Medical Education and Research, Chandigarh in 1962 with the joining of Dr. Gulati. The department provides neurosurgical services primarily to the people of Chandigarh, Punjab, Haryana, Himachal Pradesh, Jammu and Kashmir as well as the neighbouring areas of Rajasthan, Uttar Pradesh and Uttarakhand. The infrastructure and subspecialties have been developed over the last 5 decades by the dedicated and tireless efforts of the faculty and residents...
January 2017: Neurology India
https://www.readbyqxmd.com/read/28079737/dexmedetomidine-reduces-perioperative-opioid-consumption-and-postoperative-pain-intensity-in-neurosurgery-a-meta-analysis
#12
Yi Liu, Feng Liang, Xiaochen Liu, Xinxin Shao, Nan Jiang, Xiaoliang Gan
BACKGROUND: Dexmedetomidine (DEX) has been administered to patients during neurosurgery. Some studies have found that DEX could reduce perioperative opioid consumption and postoperative pain intensity. However, no firm conclusions have been reached. The purpose of this meta-analysis was to assess the efficacy of DEX for managing pain in neurosurgical patients. MATERIALS AND METHODS: A comprehensive literature review was conducted to identify randomized controlled trials (RCTs) focusing on the effects of DEX on perioperative opioid consumption and postoperative pain intensity in patients undergoing neurosurgery...
January 10, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28077536/cerebral-oxygen-saturation-and-cardiac-output-during-anaesthesia-in-sitting-position-for-neurosurgical-procedures-a-prospective-observational-study
#13
P Schramm, I Tzanova, F Hagen, M Berres, D Closhen, G Pestel, K Engelhard
BACKGROUND: Neurosurgical operations in the dorsal cranium often require the patient to be positioned in a sitting position. This can be associated with decreased cardiac output and cerebral hypoperfusion, and possibly, inadequate cerebral oxygenation. In the present study, cerebral oxygen saturation was measured during neurosurgery in the sitting position and correlated with cardiac output. METHODS: Perioperative cerebral oxygen saturation was measured continuously with two different monitors, INVOS(®) and FORE-SIGHT(®)...
October 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28072804/multidisciplinary-care-of-unruptured-brain-arteriovenous-malformations-to-improve-symptomatic-headache-and-the-onset-progression-and-outcomes-of-unruptured-brain-arteriovenous-malformations
#14
Ling-Feng Lai, Min Chen, Jia-Xiang Chen, Kuang Zheng, Xu-Ying He, Xi-Feng Li, Xin Zhang, Jian Yin, Qiu-Jing Wang, Tuan-Ming Zou, Chuan-Zhi Duan
BACKGROUND: Symptomatic headaches attributed to unruptured brain arteriovenous malformations (ubAVMs) are very common and affect patients' quality life, but multidisciplinary care of ubAVMs to improve symptomatic headache remains unclear. OBJECTIVE: The objective is to identify the features of symptomatic headaches, and to obtain headache outcomes following multidisciplinary care of ubAVMs, as well as provide background on the natural history of ubAVMs. STUDY DESIGN: The features of symptomatic headaches and headache outcomes were analyzed in a large cohort of cases after multidisciplinary care of ubAVMs...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28072743/bilateral-anterior-capsulotomy-and-amygdalotomy-for-mental-retardation-with-psychiatric-symptoms-and-aggression-a-case-report
#15
Shizhen Zhang, Peizhi Zhou, Shu Jiang, Peng Li, Wei Wang
RATIONALE: Mental retardation (MR) is a chronic condition that often has no readily identifiable cause or treatment. Aggression and psychiatric symptoms are prevalent in children with MR. Surgical treatment of aggression and psychiatric symptoms of MR is seldom investigated and studies are limited. PATIENT CONCERNS: We encountered a 19-year-old female who had MR with aggression and psychiatric symptoms. DIAGNOSES: She was diagnosed with mild MR with aggressiveness and psychiatric symptoms...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28070645/middle-cerebral-artery-aneurysms-with-intracerebral-hematoma-the-impact-of-side-and-volume-on-final-outcome
#16
Ondrej Navratil, Kamil Duris, Vilem Juran, Eduard Neuman, Karel Svoboda, Martin Smrcka
BACKGROUND: Middle cerebral artery aneurysms (MCA aneurysms) belong to the most frequent type of intracranial aneurysms forming an intracerebral hematoma. The consequences of the hematoma-the laterality, the impact of ICH volume and size of the aneurysm with the final outcome of these patients had not been studied in detail in this location, and we focused on the analysis of these factors. METHODS: Patients with MCA aneurysms and associated intracerebral hematomas with a volume ≥10 ml were studied; these were treated from January 2006 to December 2015...
January 9, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28069539/quantification-of-local-geometric-distortion-in-structural-magnetic-resonance-images-application-to-ultra-high-fields
#17
Jonathan C Lau, Ali R Khan, Tony Y Zeng, Keith MacDougall, Andrew G Parrent, Terry M Peters
Ultra-high field magnetic resonance imaging (MRI) provides superior visualization of brain structures compared to lower fields, but images may be prone to severe geometric inhomogeneity. We propose to quantify local geometric distortion at ultra-high fields in in vivo datasets of human subjects scanned at both ultra-high field and lower fields. By using the displacement field derived from nonlinear image registration between images of the same subject, focal areas of spatial uncertainty are quantified. Through group and subject-specific analysis, we were able to identify regions systematically affected by geometric distortion at air-tissue interfaces prone to magnetic susceptibility, where the gradient coil non-linearity occurs in the occipital and suboccipital regions, as well as with distance from image isocenter...
January 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/28069420/the-authors-herby-confirm-that-this-manuscript-has-neither-been-published-nor-submitted-to-any-other-journal-confocal-laser-endomicroscopy-in-neurosurgery-an-alternative-to-instantaneous-sections
#18
David Breuskin, Jacek Szczygielski, Steffi Urbschat, Yoo-Jin Kim, Joachim Oertel
INTRODUCTION: Intraoperative distinction of brain tumor from the surround brain is one of the crucial challenges in neurooncological surgery. In this study, confocal laser endomicroscope (CLE) findings were directly compared with intraoperative instantaneous sections by the neuropathologist in a blinded fashion. MATERIAL AND METHODS: The imaging device comprises of a rigid endoscope with Hopkins-Rod lenses and a red wave length laser with a scanning depth of 80 μm...
January 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28069358/pneumococcal-polysaccharide-vaccination-administered-early-after-neurotrauma-or-neurosurgery
#19
Anna Ljunghill Hedberg, Karlis Pauksens, Per Enblad, Jessika Söderberg, Björn Johansson, Helena Käyhty, Jan Sjölin
OBJECTIVES: Pneumococcal vaccination is recommended to lower the risk of posttraumatic meningitis, and early vaccination may be of importance. After both trauma and central nervous system injury, immune-suppression may occur, which could affect T-cell function and the response to T-cell dependent vaccines. We therefore aimed to investigate the response to early vaccination with a T-cell independent pneumococcal polysaccharide vaccine (PPSV). METHODS: Thirty-three patients with basilar skull fracture and 23 patients undergoing transsphenoidal pituitary gland surgery were vaccinated with PPSV within 10days after neurotrauma or neurosurgery...
January 6, 2017: Vaccine
https://www.readbyqxmd.com/read/28068277/initial-experience-with-o-arm-navigated-spinal-surgery-report-on-two-cases
#20
Ivo I Kehayov, Christo B Zhelyazkov, Borislav M Kalnev, Atanas N Davarski, Borislav D Kitov, Stefan D Raykov
Image-guided spinal surgery is becoming increasingly popular because it allows surgeons to achieve minimal invasiveness and maximum precision in the performed procedures. We present our initial experience with two cases operated on using O-arm-based spinal navigation at the Clinic of Neurosurgery in St George University Hospital, Plovdiv, Bulgaria. In the first case, we performed removal of extradural spinal tumor of the sixth thoracic vertebra and O-arm-navigated pedicle screw fixation. In the second case, we performed O-arm-navigated corpectomy of the fifth cervical vertebra and anterior spinal reconstruction and fusion with titanium expandable mesh and cervical plate in connection with degenerative narrowing of the cervical spinal canal that lead to clinically manifested myelopathy...
December 1, 2016: Folia Medica
keyword
keyword
461
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"