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antimicrobial coating

Fatemeh Kiani, Negar Ashari Astani, Reza Rahighi, Ahmad Tayyebi, Meysam Tayebi, Jafar Khezri, Ehsan Hashemi, Ursula Rothlisberger, Abdolreza Simchi
In the present work, the effect of graphene oxide (GO) nanosheets on the antibacterial activity of CuO nanowire arrays under visible light irradiation is shown. A combined thermal oxidation/electrophoretic deposition technique was employed to prepare three-dimensional networks of graphene oxide nanosheets hybridized with vertically aligned CuO nanowires. With the help of standard antibacterial assays and X-ray photoelectron spectroscopy, it is shown that the light-activated antibacterial response of the hybrid material against gram-negative Escherichia coli is significantly improved as the oxide functional groups of the GO nanosheets are reduced...
March 7, 2018: Journal of Colloid and Interface Science
Cornelia Wiegand, Andrea Völpel, Andrea Ewald, Markko Remesch, Jan Kuever, Janine Bauer, Stefanie Griesheim, Carolin Hauser, Julian Thielmann, Silke Tonndorf-Martini, Bernd W Sigusch, Jürgen Weisser, Ralf Wyrwa, Peter Elsner, Uta-Christina Hipler, Martin Roth, Carolin Dewald, Claudia Lüdecke-Beyer, Jörg Bossert
Bactericidal materials gained interest in the health care sector as they are capable of preventing material surfaces from microbial colonization and subsequent spread of infections. However, commercialization of antimicrobial materials requires proof of their efficacy, which is usually done using in vitro methods. The ISO 22196 standard (Japanese test method JIS Z 2801) is a method for measuring the antibacterial activity of daily goods. As it was found reliable for testing the biocidal activity of antimicrobially active materials and surface coatings most of the laboratories participating in this study used this protocol...
2018: PloS One
Suzanne S Dunne, Merja Ahonen, Martina Modic, Francy Rl Crijns, Minna M Keinänen-Toivola, Ruth Meinke, C William Keevil, Jim Gray, Nuala H O'Connell, Colum P Dunne
Recognized issues with poor hand hygiene compliance among healthcare workers, and reports of re-contamination of previously chemically disinfected surfaces through hand contact, emphasize need for novel hygiene methods in addition to those currently available. One such approach involves antimicrobial (nano)-coatings (AMC), whereby integrated active ingredients are responsible for elimination of microorganisms that come into contact with treated surfaces. While widely studied under laboratory conditions with promising results, studies under real life healthcare conditions are scarce...
March 14, 2018: Journal of Hospital Infection
Angie Homez Jara, Luis Daniel Daza, Diana Marcela Aguirre, José Aldemar Muñoz, José Fernando Solanilla, Henry Alexander Váquiro
Chitosan is a promising material that could be used for the development of edible coatings and films on an industrial level because of its film-forming, biodegradable, non-toxic, and antimicrobial characteristics. The aim of this work was to evaluate the effect of the polymer concentration (0.5%, 1.0%, and 1.5%) and drying temperature (2 °C, 25 °C, and 40 °C) on the physicochemical, mechanical, and thermal properties of chitosan edible films. Chitosan edible films were successfully produced using various processing conditions...
March 13, 2018: International Journal of Biological Macromolecules
Menglong Liu, Danfeng He, Tao Yang, Wei Liu, Li Mao, Yang Zhu, Jun Wu, Gaoxing Luo, Jun Deng
BACKGROUND: Silver and photothermal therapy (PTT) have been widely used for eradicating the drug-resistant bacteria. However, the risks of excess of silver for humans and the low efficiency of PTT still limit their in vivo therapeutic application. Integration of two distinctive bactericides into one entity is a promising platform to improve the efficiency of antimicrobial agents. RESULTS: In this study, a chemo-photothermal therapeutic platform based on polydopamine (PDA)-coated gold nanorods (GNRs) was developed...
March 16, 2018: Journal of Nanobiotechnology
Makoto Ashiuchi, Yuichi Hakumai, Sawami Nakayama, Haruna Higashiuchi, Kosuke Shimada
We are now entering a new age of intelligent material development using fine, sustainable polymers from extremophiles. Herein we present an innovative (but simple) means of transforming archaeal poly-γ-glutamate (PGA) into extremely durable polyionic complexes with potent antimicrobial performance. This new supra-polymer material (called PGA/DEQ) was subjected to nuclear magnetic resonance and X-ray diffraction spectroscopies to characterize in structural chemistry. Calorimetric measurements revealed its peculiar thermal properties; to the best of our knowledge, it is one of the most heat-resistant biopolymer-based polyionic complexes developed to date...
March 15, 2018: Scientific Reports
Sandra Schulz, Manfred Maitz, Stefanie Hänsel, Lars D Renner, Carsten Werner
Advanced blood contacting biomaterials are designed to combine antiseptic and anticoagulant functionalities. Here, we present a new in vitro methodology for the analysis of bacterial adhesion and growth after the preceding human whole blood incubation of the tested materials. Poly(styrene) surfaces as well as thrombin-responsive and non-responsive poly(ethylene glycol)-heparin hydrogel coatings, with and without silver functionalization, were analyzed with this approach using freshly drawn human whole blood and various human pathogens (Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli)...
March 15, 2018: Biomaterials Science
Hui Sun, Yuanxiu Hong, Yuejing Xi, Yijie Zou, Jingyi Gao, Jianzhong Du
Antimicrobial peptides (AMPs) have been attracting much attention due to their excellent antimicrobial efficiency and low rate in driving antimicrobial resistance (AMR) which has been increasing globally to alarming levels. Conjugation of AMPs into functional polymers not only preserves excellent antimicrobial activities but reduces the toxicity and offers more functionalities, which brings new insight towards developing multifunctional biomedical materials such as hydrogels, polymer vesicles, polymer micelles, etc...
March 14, 2018: Biomacromolecules
Clarence S Yah, Geoffrey S Simate, Percy Hlangothi, Benesh M Somai
Objective: The human immunodeficiency virus (HIV) is among the utmost destructive viruses humankind has ever faced in almost four decades. It carries with it profound socioeconomic and public health implications. Unfortunately, there is, currently, no effective cure for HIV infections. This review discusses the various types of condoms, microbicides, and the potential use of nanoparticle-coated condoms as a means of diminishing the risk of HIV transmission and sexually transmitted infections (STIs) during sexual intercourse...
April 2018: Annals of African Medicine
Staffan Jacob, Louis Sallé, Lucie Zinger, Alexis S Chaine, Christine Ducamp, Léa Boutault, Andrew F Russell, Philipp Heeb
The microbiota has a broad range of impacts on host physiology and behaviour, pointing out the need to improve our comprehension of the drivers of host microbiota composition. Of particular interest is whether the microbiota is acquired passively, or whether and to what extent hosts themselves shape the acquisition and maintenance of their microbiota. In birds, the uropygial gland produces oily secretions used to coat feathers that have been suggested to act as an antimicrobial defence mechanism regulating body feather microbiota...
March 13, 2018: Molecular Ecology
M Demirkurt, Y A Olcer, M M Demir, A E Eroglu
Parabens are used as antimicrobial preservatives in food, cosmetic products and pharmaceuticals regardless of their endocrine disrupting effect. In this study, highly selective molecular imprinted polymers (MIPs) were synthesized in submicron-sizes and converted to an SPME fiber coating through electrospinning process in order to determine parabens in water samples. Conversion of MIP to a fiber is achieved via creation of spacial knitting around MIP by polystyrene. The selectivity and extraction ability of the fibers were compared with the commercial fibers and the corresponding non-imprinted polymer (NIP) coated fiber...
July 19, 2018: Analytica Chimica Acta
Firas Awaja, Giorgio Speranza, Heike Kaltenegger, Débora Coraça-Huber, Birgit Lohberger
Osteo-integration and tissue regeneration are vital for the longevity, durability, and unremitting functionality of medical implants/scaffolds implanted in vivo. It's essential for biomaterials used for in vivo implantation to induce the cellular secretion of growth factors, necessary for the desired tissue generation, since the administration of artificial growth factors, in vivo, is largely prohibited. Plasma functionalized (N2 and O2 ) and stabilized Graphene Oxide (GO) thin layers in a hybrid with amorphous carbon (aC) induced the expression of vascular endothelial growth factor (VEGF) and osteoprotegerin (OPG) growth factors in fibroblasts (hGF) and, more remarkably, in osteoblasts (hFOB) cells confirming the suitability for tissue regeneration and osteo-integration applications...
March 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
Wiesława Grzesińska, Marzena Tomaszewska, Beata Bilska, Joanna Trafiałek, Michał Dziadek
Background: Providing safe food products to the consumer depends on the material and technology used and adherence to hygienic practices, throughout the production process. The degree of microbial contamination of a surface is an important indicator of equipment cleanliness and effectiveness of cleaning and disinfection. Used material, construction solutions and quality of the applied devices also have an effect on hygienic status. Objective: The objective of the present study was to evaluate the influence of the design and construction material of selected food storage racks, available on the Polish market, on their hygienic status...
2018: Roczniki Państwowego Zakładu Higieny
Nusaiba K Al-Nemrawi, Nid''A H Alshraiedeh, Aref L Zayed, Bashar M Altaani
(1) Background: Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with Tobramycin were prepared using a solvent-evaporation method. (2) Methods: The NPs were coated with low molecular weight chitosan (LMWC) to enhance the mucoadhesiveness of PLGA-NPs. The following w / w ratios of tobramycin to LMWC were prepared: control (0:0.50), F₀ (1:0.25), F₀.₅ (1:0.5), and F₁ (1:1). (3) Results: The results showed that the size of the particles increased from 220.7 nm to 575.77 nm as the concentration of LMWC used in the formulation increased...
March 8, 2018: Pharmaceuticals
Suman Joshi D S Doddapaneni, Chander Amgoth, Arunasree M Kalle, Surya Narayana Suryadevara, Krishna Satya Alapati
The synthesis and characterization of an aggregate of AgNPs coated with plant extract (PE) from Alphonsea sclerocarpa and its significant antimicrobial activity and inhibition on K562 (blood cancer) cells have been appended in the article. Synthesis of aggregate [(AgNPs)-(PE)] has been followed by a facile eco-friendly approach without using any harmful chemicals. The morphology of an aggregate [(AgNPs)-(PE)] was confirmed by TEM and SEM microscopic characterizations. Properties like solid state, the presence of functional groups, and elemental composition have been characterized through the XRD, FTIR, and EDAX...
March 2018: 3 Biotech
Hüseyin Enis Karahan, Christian Wiraja, Chenjie Xu, Jun Wei, Yilei Wang, Liang Wang, Fei Liu, Yuan Chen
Graphene materials (GMs), such as graphene, graphene oxide (GO), reduced GO (rGO), and graphene quantum dots (GQDs), are rapidly emerging as a new class of broad-spectrum antimicrobial agents. This report describes their state-of-the-art and potential future covering both fundamental aspects and biomedical applications. First, the current understanding of the antimicrobial mechanisms of GMs is illustrated, and the complex picture of underlying structure-property-activity relationships is sketched. Next, the different modes of utilization of antimicrobial GMs are explained, which include their use as colloidal dispersions, surface coatings, and photothermal/photodynamic therapy agents...
March 5, 2018: Advanced Healthcare Materials
Mohamed Shaban, Fatma Mohamed, Semsem Abdallah
Dirt and microorganisms are the major problems in textiles which can generate unpleasant odor during their growth. Here, zinc oxide (ZnO) nanoparticles prepared by sol-gel method were loaded on the cotton fabrics using spin coating technique to enhance their antimicrobial properties and water repellency. The effects of ZnO precursor concentration, precursor solution pH, number of coating runs, and Mg doping percent on the structures, morphologies, and water contact angles (WCA) of the ZnO-coated fabrics were addressed...
March 2, 2018: Scientific Reports
Ankita Vaishampayan, Anne de Jong, Darren J Wight, Jan Kok, Elisabeth Grohmann
Methicillin-resistant Staphylococcus aureus (MRSA) has become an important cause of hospital-acquired infections worldwide. It is one of the most threatening pathogens due to its multi-drug resistance and strong biofilm-forming capacity. Thus, there is an urgent need for novel alternative strategies to combat bacterial infections. Recently, we demonstrated that a novel antimicrobial surface coating, AGXX® , consisting of micro-galvanic elements of the two noble metals, silver and ruthenium, surface-conditioned with ascorbic acid, efficiently inhibits MRSA growth...
2018: Frontiers in Microbiology
André Reinhardt, Isabell Thomas, Julie Schmauck, Ralf Giernoth, Agnes Schulze, Ines Neundorf
In this study, the efficacy of electron beam irradiation versus chemical coupling for yielding polyethersulfone (PES) membranes with antibacterial properties was investigated. For the surface coating, a recently discovered lead compound, IL-KKA, comprising a short peptide sequence functionalized with imidazolium groups, was used. For better integration within the membrane, several novel variants of IL-KKA were generated. Membrane immobilization was achieved using different doses of electron beam irradiation and NHS/EDC chemical coupling...
February 27, 2018: Journal of Functional Biomaterials
L Angiolillo, A Conte, M A Del Nobile
In this work a bio-preservation technique was applied to sea bass fillets in order to preserve their quality. The preservation consisted in the application of two kinds of active coatings on the product surface differing in the fermentation time of alginate solution by L. reuteri plus glycerol (24 and 48 h). This technological strategy was chosen because it has been demonstrated that L. reuteri produces the reuterin as an intermediate metabolite during the anaerobic fermentation of glycerol. To assess the antimicrobial effects of sodium alginate with L...
January 10, 2018: International Journal of Food Microbiology
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