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antimicrobial coating

Xun Niu, Yating Liu, Yang Song, Jinquan Han, Hui Pan
Cellulose nanofiber (CNF) was modified by rosin and used as a reinforcement filler within a polylactic acid (PLA) matrix. The resulting film was then coated with chitosan (CHT) to prepare a two-layer composite film for antimicrobial food packaging. The FT-IR spectra of rosin modified CNF (R-CNF) displayed a clear peak at 1730cm-1, which confirmed the successful esterification of CNF by rosin. The R-CNF showed a better dispersion in PLA matrix than CNF and the loading of R-CNF had a significant effect on the mechanical properties of the resulting film...
March 1, 2018: Carbohydrate Polymers
Minyu Xiao, Joshua Jasensky, Leanna L Foster, Kenichi Kuroda, Zhan Chen
Antimicrobial peptides (AMPs) free in solution can kill bacteria by disrupting bacterial cell membranes. Their modes of action have been extensively studied and various models ranging from Pore formation to Carpet-like mechanism were proposed. Surface immobilized AMPs have been used as coatings to kill bacteria and as sensors to capture bacteria, but the interaction mechanisms of surface immobilized AMPs and bacteria are not fully understood. In this research, an analytical platform, SFG-microscope, which is composed of a sum frequency generation (SFG) vibrational spectrometer and a fluorescence microscope, was used to probe molecular interactions between surface immobilized AMPs and bacteria in situ in real time at the solid/liquid interface...
January 15, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
L Hakobyan, J Pla Tolos, Y Moliner-Martinez, C Molins-Legua, Jesús Ruiz Ramos, M Gordon, Paula Ramirez-Galleymore, P Campins-Falco
Meropenem is a widely used antimicrobial for the treatment of infections associated with the use of invasive medical devices in intensive care unit patients. These treatments are not always effective, in fact, in-vitro studies have demonstrated the difficulty of antimicrobials to penetrate into the biofilm, however in-vivo studies of the effect of these compounds is a trend, mostly because of the complexity of pulmonary samples extracted from ETTs. Therefore, the objective of this study was to evaluate in-tube solid phase microextraction (in-tube SPME) coupled to capillary liquid chromatography (CapLC) with DAD to determine meropenem in ETTs in order to estimate the penetration capability into the biofilm...
January 8, 2018: Journal of Pharmaceutical and Biomedical Analysis
Ferne T Elsass
INTRODUCTION: Pediatric patients develop mucositis when receiving treatments such as chemotherapy and radiation; the most common and sensitive is oral mucositis. Mouth rinses containing antimicrobial, antihistamine, and analgesic medications are the mainstay for pediatric patients; however, patients often refuse these rinses due to the taste or texture. Also, patients under 1 year of age are unable to use these products. OBJECTIVE: Herein, the improvement of oral mucositis with standard oral care and additional use of active Leptospermum honey in pediatric oncology patients after chemotherapy is demonstrated...
December 2017: Wounds: a Compendium of Clinical Research and Practice
Ping-Ching Wu, Hua-Han Chen, Shih-Yao Chen, Wen-Lung Wang, Kun-Lin Yang, Chia-Hung Huang, Hui-Fang Kao, Jui-Cheng Chang, Chih-Li Lilian Hsu, Jiu-Yao Wang, Ting-Mao Chou, Wen-Shuo Kuo
BACKGROUND: The results showed that the deciding factor is the culture medium in which the bacteria and the graphene oxide (GO) are incubated at the initial manipulation step. These findings allow better use of GO and GO-based materials more and be able to clearly apply them in the field of biomedical nanotechnology. RESULTS: To study the use of GO sheets applied in the field of biomedical nanotechnology, this study determines whether GO-based materials [GO, GO-polyoxyalkyleneamine (POAA), and GO-chitosan] stimulate or inhibit bacterial growth in detail...
January 10, 2018: Journal of Nanobiotechnology
Sunita Panda, Tapan K Rout, Agnish Dev Prusty, Pulickel M Ajayan, Sasmita Nayak
Nanomaterials such as silver nanoparticles and graphene-based composites are known to exhibit biocidal activities. However, interactions with surrounding medium or supporting substrates can significantly influence this activity. Here, it is shown that superior antimicrobial properties of natural shellac-derived graphene oxide (GO) coatings is obtained on metallic films, such as Zn, Ni, Sn, and steel. It is also found that such activities are directly correlated to the electrical conductivity of the GO-metal systems; the higher the conductivity the better is the antibacterial activity...
January 8, 2018: Advanced Materials
Andreas Obermeier, Jochen Schneider, Norbert Harrasser, Jutta Tübel, Heinrich Mühlhofer, Dominik Pförringer, Constantin von Deimling, Peter Foehr, Barbara Kiefel, Christina Krämer, Axel Stemberger, Matthias Schieker, Rainer Burgkart, Rüdiger von Eisenhart-Rothe
BACKGROUND: Surgical sutures can promote migration of bacteria and thus start infections. Antiseptic coating of sutures may inhibit proliferation of adhered bacteria and avoid such complications. OBJECTIVES: This study investigated the inhibition of viable adhering bacteria on novel antimicrobially coated surgical sutures using chlorhexidine or octenidine, a critical factor for proliferation at the onset of local infections. The medical need, a rapid eradication of bacteria in wounds, can be fulfilled by a high antimicrobial efficacy during the first days after wound closure...
2018: PloS One
Tian Ren, Mingyu Qiao, Lei Zhang, Jean Weese, Tung-Shi Huang, Xuehong Ren
The antimicrobial activity of 1-chloro-2,2,5,5-tetramethyl-4-imidazoidinone (MC), a nonbleaching N-halamine compound, was investigated on materials commonly used in broiler production, including stainless steel, galvanized metal, aluminum, plastic, and pressure-treated wood. MC aqueous solutions at 0.02, 0.04, and 0.06% were challenged with Salmonella Typhimurium and Campylobacter jejuni at 6 log CFU/mL, resulting in complete inactivation of both bacteria in 30 min with 0.06% MC. Follow-up experiments were performed using test materials treated with 0...
February 2018: Journal of Food Protection
Lijun Ding, Hao Wang, Dan Liu, Zhengnan Zheng
The growing number of microbial cross-contamination events necessitates the development of novel antimicrobial strategies in the food industry. In this study, a polypropylene nonwoven fabric (PPNWF) was grafted with a natural antimicrobial component, aloe emodin (AE), and its antimicrobial performance was evaluated. The grafted samples (PPNWF-g-AE) were examined using Fourier transform infrared spectroscopy and scanning electron microscopy. AE was effectively grafted onto the surface of the PPNWF through the adsorption covalent effect...
February 2018: Journal of Food Protection
Aleksandra Ivanova, Kristina Ivanova, Javier Hoyo, Thomas Heinze, Susana Sanchez-Gomez, Tzanko Tzanov
Bacteria-mediated diseases are a global healthcare concern due to the development and spread of antibiotic resistant strains. Cationic compounds are considered membrane active biocidal agents having a great potential to control bacterial infections, while limiting the emergence of drug resistance. Herein, the versatile and simple Layer-by-Layer (LbL) technique was used to coat alternating multilayers of an antibacterial aminocellulose conjugate and the biocompatible hyaluronic acid on biocompatible polymer nanoparticles (NPs), taking advantage of the nano-size of these otherwise biologically inert templates...
January 9, 2018: ACS Applied Materials & Interfaces
Yiyan Song, Huijun Jiang, Bangbang Wang, Yan Kong, Jin Chen
To tackle severe environmental pollution, a search for materials by economical and eco-friendly preparations is demanding for public health. In this study, a novel in situ method to form silver nanoparticles under mild conditions was developed using biomimetic reducing agents of polydopamine coated on the rodlike mesoporous silica of SBA-15. The synthesized SBA-15/polydopamine (PDA)/Ag nanocomposites were characterized by a combination of physicochemical and electrochemical methods. 4-Nitrophenol (4-NP) and methylene blue (MB) were used as models for the evaluation of the prepared nanocatalysts of SBA-15/PDA/Ag in which the composite exhibited enhanced catalytic performance toward degrading 4-NP in solution and MB on the membrane, respectively...
January 5, 2018: ACS Applied Materials & Interfaces
Minggang Yang, Peipei Jiang, Yang Ge, Fang Lan, Xuedong Zhou, Jing He, Yao Wu
The clinical success of dental implants requires not only the optimum osseointegration but also the integration of implant surface with soft tissues to form biological sealing. In this study, alkali-heat treatment was applied to modify the pure titanium surface constructing a unique micro-and nano-structure. Then, poly(dopamine), along and with the additional incorporation of hydroxyapatite and carboxymethyl chitosan have been successfully infiltrated into the preactivated Ti surface during dopamine self-polymerization proceeding...
January 1, 2018: Journal of Biomaterials Applications
Patricia Milagros Maquera Huacho, Marianne N Marques Nogueira, Fernanda G Basso, Miguel Jafelicci Junior, Renata S Francisconi, Denise M P Spolidorio
The aim of this study was to evaluate the surface free energy (SFE), wetting and surface properties as well as antimicrobial, adhesion and biocompatibility properties of diamond-like carbon (DLC)-coated surfaces. In addition, the leakage of Escherichia coli through the abutment-dental implant interface was also calculated. SFE was calculated from contact angle values; R a was measured before and after DLC coating. Antimicrobial and adhesion properties against E. coli and cytotoxicity of DLC with human keratinocytes (HaCaT) were evaluated...
May 2017: Brazilian Dental Journal
M A Ruíz-Gómez, M Z Figueroa-Torres, I L Alonso-Lemus, O E Vega-Becerra, J R González-López, A A Zaldívar-Cadena
An electroless deposition process was used to synthesize with a controlled morphology, polycrystalline ZnO on glass substrates as antimicrobial coatings. The influence of deposition temperature (Tdep) on the physicochemical and antimicrobial properties of the ZnO films was analyzed. The results indicated that a change in deposition temperature greatly affected the morphology and the degree of crystallinity of the films. Scanning electron microscope images show that the film surface is porous at a deposition temperature of 40 and 50 °C, whereas hexagonal-plate shaped morphology predominated at 60 °C and finally at 70 and 80 °C the films consisted of rod-like particles...
December 17, 2017: Journal of Hazardous Materials
Aharon Gedanken, Nina Perkas, Ilana Perelshtein, Anat Lipovsky
The review, reports on the functionalization of textiles for the treatment of wounds and skin diseases such as acne. In view of the growing demand for high-quality textiles, much research is focused on the creation of antimicrobial finishings for fabrics, in order to protect customers from pathogenic or odor-generating microorganisms. We present coatings from inorganic, organic and biochemical nanoparticles (NPs) on surfaces that impart the ability to kill bacteria, avoid biofilm formation and speed up the recovery of wounds...
December 29, 2017: Current Medicinal Chemistry
Andrew Boden, Mrinal Bhave, Peng-Yuan Wang, Snehal R Jadhav, Peter Kingshott
The ability of bacteria to form biofilms and the emergence of antibiotic-resistant strains has prompted the need to develop the next-generation of antibacterial coatings. Antimicrobial peptides (AMPs) are showing promise as molecules that can address these issues, especially if used when immobilized as a surface coating. We present a method that explores how surface patterns together with the selective immobilization of an AMP called PuroA (FPVTWRWWKWWKG-NH2) can be used to both kill bacteria, but also as a tool to study bacterial attachment mechanisms...
December 28, 2017: ACS Applied Materials & Interfaces
Timothy Briggs, Gordon Blunn, Simon Hislop, Rita Ramalhete, Caroline Bagley, David McKenna, Melanie Coathup
Periprosthetic joint infection (PJI) is associated with high patient morbidity and a large financial cost. This study investigated Photodynamic Therapy (PDT) as a means of eradicating bacteria that cause PJI, using a laser with a 665-nm wavelength and methylene blue (MB) as the photosensitizer. The effectiveness of MB concentration on the growth inhibition of methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Pseudomonas aeruginosa and Acinetobacter baumannii was investigated...
December 15, 2017: Lasers in Medical Science
Jeffery A Weisman, Udayabhanu Jammalamadaka, Karthik Tappa, David K Mills
Previous studies have established halloysite nanotubes (HNTs) as viable nanocontainers capable of sustained release of a variety of antibiotics, corrosion agents, chemotherapeutics and growth factors either from their lumen or in outer surface coatings. Accordingly, halloysite nanotubes (HNTs) hold great promise as drug delivery carriers in the fields of pharmaceutical science and regenerative medicine. This study explored the potential of 3D printing drug doped HNT constructs. We used a model drug, gentamicin (GS) and polylactic acid (PLA) to fabricate GS releasing disks, beads, and pellets...
December 15, 2017: Bioengineering
Teresita Arredondo-Ochoa, Blanca E García-Almendárez, Monserrat Escamilla-García, Olga Martín-Belloso, Giovanna Rossi-Márquez, Luis Medina-Torres, Carlos Regalado-González
Nanoemulsions are feasible delivery systems of lipophilic compounds, showing potential as edible coatings with enhanced functional properties. The aim of this work was to study the effect of emulsifier type (stearic acid (SA), Tween 80 (T80) or Tween 80/Span 60 (T80/S60)) and emulsification process (homogenization, ultrasound or microfluidization) on nanoemulsion formation based on oxidized corn starch, beeswax (BW) and natural antimicrobials (lauric arginate and natamycin). The response variables were physicochemical properties, rheological behavior, wettability and antimicrobial activity of BW-starch nanoemulsions (BW-SN)...
December 15, 2017: International Journal of Molecular Sciences
Wencai Zhou, Salma Begum, Zhengbang Wang, Peter Krolla, Danny Wagner, Stefan Bräse, Christof Wöll, Manuel Tsotsalas
Development of surface coatings with high antimicrobial activity is urgently required to fight bacteria and other microorganisms on technical and hygiene relevant surfaces. Control over structure and topology of the surface coatings, combined with the ability to include functional molecules within the structure is crucial for optimizing their performance. Herein, we describe a novel strategy to synthesize structurally well-defined porphyrin polymer thin films via a template approach. In this approach bis-azido functionalized porphyrin molecules are preorganized within a metal-organic framework (MOF) structure...
December 15, 2017: ACS Applied Materials & Interfaces
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