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https://www.readbyqxmd.com/read/28428175/flavored-e-cigarette-liquids-reduce-proliferation-and-viability-in-the-calu3-airway-epithelial-cell-line
#1
Temperance R Rowell, Steven L Reeber, Shernita L Lee, Rachel A Harris, Rachel C Nethery, Amy H Herring, Gary L Glish, Robert Tarran
E-cigarettes are generally thought of as a safer smoking alternative to traditional cigarettes. However, little is known about the effects of e-cigarette liquids (e-liquids) on the lung. Since over 7,000 unique flavors have been identified for purchase in the USA, our goal was to conduct a screen that would test whether different flavored e-liquids exhibited different toxicant profiles. We tested the effects of 13 different flavored e-liquids (with nicotine and propylene glycol/vegetable glycerin (PG/VG) serving as controls) on a lung epithelial cell line (CALU3)...
April 20, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28420881/reduced-biological-effect-of-e-cigarette-aerosol-compared-to-cigarette-smoke-evaluated-in-vitro-using-normalized-nicotine-dose-and-rna-seq-based-toxicogenomics
#2
Linsey E Haswell, Andrew Baxter, Anisha Banerjee, Ivan Verrastro, Jessica Mushonganono, Jason Adamson, David Thorne, Marianna Gaça, Emmanuel Minet
Electronic cigarettes (e-cigarettes) use has increased globally and could potentially offer a lower risk alternative to cigarette smoking. Here, we assessed the transcriptional response of a primary 3D airway model acutely exposed to e-cigarette aerosol and cigarette (3R4F) smoke. Aerosols were generated with standard intense smoking regimens with careful consideration for dose by normalizing the exposures to nicotine. Two e-cigarette aerosol dilutions were tested for equivalent and higher nicotine delivery compared to 3R4F...
April 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28414981/claims-in-vapour-device-e-cigarette-regulation-a-narrative-policy-framework-analysis
#3
Renée O'Leary, Ron Borland, Tim Stockwell, Marjorie MacDonald
BACKGROUND: The electronic cigarette or e-cigarette (vapour device) is a consumer product undergoing rapid growth, and governments have been adopting regulations on the sale of the devices and their nicotine liquids. Competing claims about vapour devices have ignited a contentious debate in the public health community. What claims have been taken up in the state arena, and how have they possibly influenced regulatory outcomes? METHODS: This study utilized Narrative Policy Framework to analyze the claims made about vapour devices in legislation recommendation reports from Queensland Australia, Canada, and the European Union, and the 2016 deeming rule legislation from the United States, and examined the claims and the regulatory outcomes in these jurisdictions...
April 14, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28412133/the-southwest-uk-burns-network-swuk-experience-of-electronic-cigarette-explosions-and-review-of-literature
#4
A Arnaout, H Khashaba, T Dobbs, F Dewi, S Pope-Jones, A Sack, C Estela, D Nguyen
INTRODUCTION: Since the introduction of e-cigarettes to the UK market in 2007 their popularity amongst young adults has significantly increased. These lithium-ion powered devices remain unregulated by the Standards Agency and as a result burns centres across the world have seen an increasing number of patients presenting with significant burns, resulting from poor quality batteries that appear to be liable to explode when over-heated, over-charged or incorrectly stored. METHODS: Retrospective and perspective review of all e-cigarette related burns presenting to the Southwest Burns Network; South Wales Burns Centre (Morriston Hospital) or to Bristol burns centre (Southmead Hospital) between Oct 15-July 16, followed by a review of available literature performed and eligible papers identified using PRISMA 2009 Checklist...
April 12, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28409740/quit-methods-used-by-us-adult-cigarette-smokers-2014-2016
#5
Ralph S Caraballo, Paul R Shafer, Deesha Patel, Kevin C Davis, Timothy A McAfee
To quantify the prevalence of 10 quit methods commonly used by adult cigarette smokers, we used data from a nationally representative longitudinal (2014-2016) online survey of US adult cigarette smokers (n = 15,943). Overall, 74.7% of adult current cigarette smokers used multiple quit methods during their most recent quit attempt. Giving up cigarettes all at once (65.3%) and reducing the number of cigarettes smoked (62.0%) were the most prevalent methods. Substituting some cigarettes with e-cigarettes was used by a greater percentage of smokers than the nicotine patch, nicotine gum, or other cessation aids approved by the US Food and Drug Administration...
April 13, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28404499/the-scottish-adolescent-e-cigarette-user-profiling-from-the-scottish-schools-adolescent-lifestyle-and-substance-use-survey-salsus
#6
N Kaufmann, D Currie
No abstract text is available yet for this article.
March 28, 2017: Public Health
https://www.readbyqxmd.com/read/28404498/prevalence-of-e-cigarette-use-among-adolescents-in-13-eastern-european-towns-and-cities
#7
A L Kristjansson, M J Mann, J Sigfusson, E A Sarbu, J Grubliauskiene, S M Daily, I D Sigfusdottir
No abstract text is available yet for this article.
March 28, 2017: Public Health
https://www.readbyqxmd.com/read/28401822/herziene-richtlijn-%C3%A2-behandeling-van-tabaksverslaving-en-stoppen-met-roken-ondersteuning%C3%A2
#8
N H Chavannes, E Meijer, L Wind, R C van der Graaf, C Rietbergen, E A Croes
- The revised guideline 'Treatment of tobacco addiction and smoking cessation support' offers health professionals a framework to provide evidence-based care to patients who smoke, which should aid in reducing smoking prevalence and smoke-related morbidity and mortality.- Four topics of the guideline have been revised: behavioural interventions, pharmacotherapy, e-health interventions and e-cigarettes. For the other topics, the recommendations from the 2009 version remain unaltered.- It is important that health professionals offer a made-to-measure smoking cessation advice and apply a fit-for-purpose smoking cessation intervention...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28401670/adolescents-behavioral-and-neural-responses-to-e-cigarette-advertising
#9
Yvonnes Chen, Carina H Fowler, Vlad B Papa, Rebecca J Lepping, Morgan G Brucks, Andrew T Fox, Laura E Martin
Although adolescents are a group heavily targeted by the e-cigarette industry, research in cue-reactivity has not previously examined adolescents' behavioral and neural responses to e-cigarette advertising. This study addressed this gap through two experiments. In Experiment One, adult traditional cigarette smokers (n = 41) and non-smokers (n = 41) answered questions about e-cigarette and neutral advertising images. The 40 e-cigarette advertising images that most increased desire to use the product were matched to 40 neutral advertising images with similar content...
April 11, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28396620/correlates-of-e-cigarette-ad-awareness-and-likeability-in-u-s-young-adults
#10
Jessica M Rath, Lyubov Teplitskaya, Valerie F Williams, Jennifer L Pearson, Donna M Vallone, Andrea C Villanti
BACKGROUND: Awareness and use of electronic cigarettes has rapidly increased among U.S. adults. The aim of this study was to examine awareness and likeability of e-cigarette print advertisements in a national sample of young adults and to examine ad likeability as a correlate of intended e-cigarette use among never e-cigarette users. METHODS: Participants (n = 2110, unweighted) of the Truth Initiative Young Adult Cohort (January 2013) were randomized to see four print ads (blu, Fin, NJOY, and White Cloud)...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28393558/supraventricular-tachycardia-and-acute-confusion-following-ingestion-of-e-cigarette-fluid-containing-ab-fubinaca-and-adb-fubinaca-a-case-report-with-quantitative-analysis-of-serum-drug-concentrations
#11
Rex Pui Kin Lam, Magdalene Huen Yin Tang, Siu Chung Leung, Yeow Kuan Chong, Matthew Sik Hon Tsui, Tony Wing Lai Mak
BACKGROUND: AB-FUBINACA and ADB-FUBINACA are structurally similar synthetic cannabinoids with potent CB1 receptor agonistic effects. Very little is known about their pharmacology and toxicology. OBJECTIVE: To report a case of supraventricular tachycardia and acute confusion after ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA, with quantitative analysis of the serum drug concentrations. CASE REPORT: A healthy 24-year-old man ingested two drops of e-cigarette fluid which were later found to contain AB-FUBINACA and ADB-FUBINACA...
April 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28393137/aldehyde-detection-in-electronic-cigarette-aerosols
#12
Mumiye A Ogunwale, Mingxiao Li, Mandapati V Ramakrishnam Raju, Yizheng Chen, Michael H Nantz, Daniel J Conklin, Xiao-An Fu
Acetaldehyde, acrolein, and formaldehyde are the principal toxic aldehydes present in cigarette smoke and contribute to the risk of cardiovascular disease and noncancerous pulmonary disease. The rapid growth of the use of electronic cigarettes (e-cigarettes) has raised concerns over emissions of these harmful aldehydes. This work determines emissions of these aldehydes in both free and bound (aldehyde-hemiacetal) forms and other carbonyls from the use of e-cigarettes. A novel silicon microreactor with a coating phase of 4-(2-aminooxyethyl)-morpholin-4-ium chloride (AMAH) was used to trap carbonyl compounds in the aerosols of e-cigarettes via oximation reactions...
March 31, 2017: ACS Omega
https://www.readbyqxmd.com/read/28393086/nicotine-delivery-and-vaping-behavior-during-ad-libitum-e-cigarette-access
#13
Gideon St Helen, Kathryn C Ross, Delia A Dempsey, Christopher M Havel, Peyton Jacob, Neal L Benowitz
OBJECTIVE: To characterize vaping behavior and nicotine intake during ad libitum e-cigarette access. METHODS: Thirteen adult e-cigarette users had 90 minutes of videotaped ad libitum access to their usual e-cigarette. Plasma nicotine was measured before and every 15 minutes after the first puff; subjective effects were measured before and after the session. RESULTS: Average puff duration and interpuff interval were 3.5±1.4 seconds (±SD) and 118±141 seconds, respectively...
October 2016: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/28393082/electronic-cigarette-use-among-current-smokers-a-pilot-qualitative-study
#14
Ban A Majeed, Cassandra A Stanton, Shanta R Dube, Kymberle L Sterling, Joy D Burns, Michael P Eriksen
OBJECTIVE: This pilot study explored psychosocial influences of e-cigarette use among dual users. METHODS: Two focus groups among adult current smokers who had ever used e-cigarettes were conducted in Georgia. Discussions were audio-recorded. Principles of grounded theory and thematic analysis were employed. RESULTS: Reasons for initial use included curiosity and social influence. Themes related to regular use included enjoyment of sensory experiences and perception of reduced harm...
November 2016: Health Behavior and Policy Review
https://www.readbyqxmd.com/read/28392919/respiratory-bronchiolitis-associated-interstitial-lung-disease-secondary-to-electronic-nicotine-delivery-system-use-confirmed-with-open-lung-biopsy
#15
Mark Flower, Lakshmy Nandakumar, Mahendra Singh, David Wyld, Morgan Windsor, David Fielding
As a modern phenomenon, there is currently limited understanding of the possible toxic effects and broader implications of electronic nicotine delivery systems (ENDS). Large volumes of aerosolized particles are inhaled during "vaping" and there are now an increasing number of case reports demonstrating toxic effects of ENDS, as well as human studies demonstrating impaired lung function in users. This article presents a case of respiratory bronchiolitis interstitial lung disease (RB-ILD) precipitated by vaping in a 33-year-old male with 10 pack years of traditional cigarette and prior treatment for mixed germ cell tumour...
May 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28391965/e-cigarette-use-cigarette-smoking-dual-use-and-problem-behaviors-among-u-s-adolescents-results-from-a-national-survey
#16
Sean Esteban McCabe, Brady T West, Phil Veliz, Carol J Boyd
PURPOSE: There is a need to obtain greater clarity regarding adolescents' e-cigarette use and the associations of use with a wider range of risk behaviors. This study examines the associations among past-month e-cigarette use only, traditional cigarette smoking only, dual use (i.e., concurrent e-cigarette use and cigarette smoking), school-related (i.e., truancy and poor academic performance) risk behaviors, and substance-related (i.e., alcohol use, binge drinking, marijuana use, illicit drug use, and nonmedical prescription drug use) risk behaviors...
April 5, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28389330/a-comparison-of-nicotine-dependence-among-exclusive-e-cigarette-and-cigarette-users-in-the-path-study
#17
Guodong Liu, Emily Wasserman, Lan Kong, Jonathan Foulds
Electronic cigarettes ("e-cigs") have recently gained in popularity, but their health risks, including dependence potential are unclear. This study analyzed the adult database from the Wave 1 Population Assessment of Tobacco and Health (PATH) Study, a nationally representative survey of tobacco use in the United States, to assess the relative level of dependence among adult, exclusive everyday users of e-cigarettes and cigarettes. Of the total 32,320 observations from the Wave 1 PATH adult database, 3586 (5...
April 4, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28387931/e-cigarettes-expand-tobacco-use-among-adolescents
#18
Carrie Printz
No abstract text is available yet for this article.
April 15, 2017: Cancer
https://www.readbyqxmd.com/read/28387825/misplaced-trust-racial-differences-in-use-of-tobacco-products-and-trust-in-sources-of-tobacco-health-information
#19
Héctor E Alcalá, Mienah Z Sharif, Brittany N Morey
Introduction: Recently, the rates of utilization of alternative tobacco products have increased. Providing health information about tobacco products from trustworthy sources may help decrease the popularity of these products. Using a nationally representative study of adults, we fill the current gap in research on racial and ethnic disparities in utilization of alternative tobacco products as well as in trust of sources of health information about tobacco products. Methods: Data came from the Health Information National Trends Survey (HINTS) (N=3,738), which was collected in 2015...
April 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28387073/-electronic-cigarette-state-of-the-science-about-toxicological-aspects
#20
REVIEW
M Deville, C Charlier
Electronic cigarettes (e-cigarettes) are presented as a healthier alternative to tobacco smoking. They are designed to contain a solution which is heated to produce an aerosol inhaled by the user. The liquid is mainly composed of propylene glycol, glycerol, flavours and, in some cases, nicotine. Except for nicotine, which can be fatal when ingested at high dose, these components are generally considered as safe. However, the potential effect of long term exposure to inhaled propylene glycol is unknown at this time...
January 2017: Revue Médicale de Liège
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