Read by QxMD icon Read


A J Sutton, R S Vohra, M Hollyman, P J Marriott, A Buja, D Alderson, S Pasquali, E A Griffiths
BACKGROUND: The optimal timing of cholecystectomy for patients admitted with acute gallbladder pathology is unclear. Some studies have shown that emergency cholecystectomy during the index admission can reduce length of hospital stay with similar rates of conversion to open surgery, complications and mortality compared with a 'delayed' operation following discharge. Others have reported that cholecystectomy during the index acute admission results in higher morbidity, extended length of stay and increased costs...
October 20, 2016: British Journal of Surgery
(no author information available yet)
BACKGROUND: The aims of this prospective population-based cohort study were to identify the patient and hospital characteristics associated with emergency cholecystectomy, and the influences of these in determining variations between hospitals. METHODS: Data were collected for consecutive patients undergoing cholecystectomy in acute UK and Irish hospitals between 1 March and 1 May 2014. Potential explanatory variables influencing the performance of emergency cholecystectomy were analysed by means of multilevel, multivariable logistic regression modelling using a two-level hierarchical structure with patients (level 1) nested within hospitals (level 2)...
October 17, 2016: British Journal of Surgery
Wee Tin K Kao, Lorne S Parnes, Richard A Chole
OBJECTIVES/HYPOTHESIS: Benign paroxysmal positional vertigo (BPPV) is the most common vestibular disorder with an incidence between 10.7 and 17.3 per 100,000 persons per year. The mechanism for BPPV has been postulated to involve displaced otoconia resulting in canalithiasis. Although particulate matter has been observed in the endolymph of affected patients undergoing posterior canal occlusion surgery, an otoconial origin for the disease is still questioned. STUDY DESIGN: In this study, particulate matter was extracted from the posterior semicircular canal of two patients and examined with scanning electron microscopy...
October 11, 2016: Laryngoscope
Robert P Sutcliffe, Marianne Hollyman, James Hodson, Glenn Bonney, Ravi S Vohra, Ewen A Griffiths
BACKGROUND: Laparoscopic cholecystectomy is commonly performed, and several factors increase the risk of open conversion, prolonging operating time and hospital stay. Preoperative stratification would improve consent, scheduling and identify appropriate training cases. The aim of this study was to develop a validated risk score for conversion for use in clinical practice. PATIENTS AND METHODS: Preoperative patient and disease-related variables were identified from a prospective cholecystectomy database (CholeS) of 8820 patients, divided into main and validation sets...
August 30, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
(no author information available yet)
BACKGROUND: The aim was to describe the management of benign gallbladder disease and identify characteristics associated with all-cause 30-day readmissions and complications in a prospective population-based cohort. METHODS: Data were collected on consecutive patients undergoing cholecystectomy in acute UK and Irish hospitals between 1 March and 1 May 2014. Potential explanatory variables influencing all-cause 30-day readmissions and complications were analysed by means of multilevel, multivariable logistic regression modelling using a two-level hierarchical structure with patients (level 1) nested within hospitals (level 2)...
August 26, 2016: British Journal of Surgery
Wee Tin K Kao, Patricia M Gagnon, Joseph P Vogel, Richard A Chole
HYPOTHESIS: Bacterial biofilm formation within cholesteatomas is responsible for increased persistence and tissue destruction and Pseudomonas aeruginosa deficient in biofilm formation (PAO1 ΔfleQ) are less virulent than the parent bacteria. BACKGROUND: Infected aural cholesteatomas have been demonstrated to be more destructive than uninfected cholesteatomas and infections are more persistent. The chronicity and persistence of infections within cholesteatomas may be because of the presence of biofilm formation...
August 2016: Otology & Neurotology
Osama H Abd Ella, Abdallah E Mohammad
Infection with Dicrocoelium dendriticum in humans is seldom to be reported in Egypt. This liver fluke, which commonly infects ruminants, has a complex life cycle with two intermediate hosts; the land snail and the ant. Human infection occurs by accidental ingestion of the second intermediate host. The present reported a patient suffered from recurrent acute chole-cystitis with chronic urinary schistosomiasis whose Kato stool examination showed Dicroceolium dendriticum eggs. He was successfully treated with Mirazid...
December 2015: Journal of the Egyptian Society of Parasitology
Maria Luisa Forchielli, Matteo Conti, Daniela Patrono, Rita Mancini, Andrea Pession, Cristina Puggioli, Germana Bersani
No data exist for vitamin A group and vitamin D2/D3 content in branded intravenous lipid emulsions (ILEs). Our goal is to evaluate and quantify their concentrations in different ILEs to assess whether they are clinically relevant. Analyses were carried out in triplicates on six ILEs: 1) 30% soybean oil-based, 2) 20% olive-soybean oil based, 3) 10 + 10% soybean - MCT coconut oil based, 4) 20% soybean-olive-MCT-fish oil based, 5) 20% soybean-MCT-fish oil based and 6) 10% pure fish oil based, respectively. Retinol group (vitamin A) and ergo-chole-calciferol (vitamin D2/D3) were analyzed and quantified by a quali-quantitative Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) method after potassium hydroxide alkaline hydrolysis, hexane extraction, reverse phase-liquid chromatography and specific multiple-reaction-monitoring (MRM) detection...
January 29, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Jianjun Zhang, Guangyuan Meng, Chen Zhang, Lin Lin, Nuo Xu, Min Liu, Fangyuan Cui, Le Jia
BACKGROUND: Edible mushrooms, especially the genus of Pleurotus, have been well studied for their nutrition as well as non-toxic medicinal properties. Recently, much attention has been paid to the therapeutic values of mushrooms in genus of Pleurotus with diabetes mellitus (DM), which was a complex metabolic disorder that induced by increased oxidative stress and characterized by hyperglycemia. However, scare attention has been paid to polysaccharides from P. djamor. Meanwhile, zinc is an essential trace element in the human body and it participates in various pathways of metabolism...
2015: BMC Complementary and Alternative Medicine
Hanna Cholé, Pierre Junca, Jean-Christophe Sandoz
In honeybees, two olfactory conditioning protocols allow the study of appetitive and aversive Pavlovian associations. Appetitive conditioning of the proboscis extension response (PER) involves associating an odor, the conditioned stimulus (CS) with a sucrose solution, the unconditioned stimulus (US). Conversely, aversive conditioning of the sting extension response (SER) involves associating the odor CS with an electric or thermal shock US. Each protocol is based on the measure of a different behavioral response (proboscis versus sting) and both only provide binary responses (extension or not of the proboscis or sting)...
December 2015: Learning & Memory
Richard A Chole, David J Lim
No abstract text is available yet for this article.
March 2016: Laryngoscope
Terence M Myckatyn, Justin Cohen, Richard A Chole
No abstract text is available yet for this article.
January 2016: Plastic and Reconstructive Surgery
S Pasquali, M Boal, E A Griffiths, D Alderson, R S Vohra
BACKGROUND: The effectiveness of perioperative antibiotics in reducing surgical-site infection (SSI) and overall nosocomial infections in patients undergoing laparoscopic cholecystectomy for biliary colic and low- and moderate-risk cholecystitis (Tokyo classification) is unclear. A systematic review and meta-analysis was performed to assess this. METHODS: Searches were conducted of the MEDLINE, Embase and Cochrane databases. Only randomized clinical trials (RCTs) were included...
January 2016: British Journal of Surgery
Louis Poppler, Justin Cohen, Utku Can Dolen, Andrew E Schriefer, Marissa M Tenenbaum, Corey Deeken, Richard A Chole, Terence M Myckatyn
BACKGROUND: Subclinical infections, manifest as biofilms, are considered an important cause of capsular contracture. Acellular dermal matrices (ADMs) are frequently used in revision surgery to prevent recurrent capsular contractures. OBJECTIVE: We sought to identify an association between capsular contracture and biofilm formation on breast prostheses, capsules, and ADMs in a tissue expander/implant (TE/I) exchange clinical paradigm. METHODS: Biopsies of the prosthesis, capsule, and ADM from patients (N = 26) undergoing TE/I exchange for permanent breast implant were evaluated for subclinical infection...
August 2015: Aesthetic Surgery Journal
Michael Sugrue, Shaheel M Sahebally, Luca Ansaloni, Martin D Zielinski
INTRODUCTION: Variation in outcomes from surgery is a major challenge and defining surgical findings may help set benchmarks, which currently do not exist in laparoscopic cholecystectomy. This study outlines a new surgical scoring system incorporating key operative findings. METHODS: English language studies (from January 1965 to July 2014) pertaining to severity scoring and predictors of difficult laparoscopic cholecystectomy were searched for in PubMed, Embase and Cochrane databases using the search terms 'Laparoscopic cholecystectomy or Lap chole' and/or 'Scoring Index or Grading system or Prediction of difficulty or Conversion to open' in various combinations...
2015: World Journal of Emergency Surgery: WJES
Ravinder S Vohra, Philip Spreadborough, Marianne Johnstone, Paul Marriott, Aneel Bhangu, Derek Alderson, Dion G Morton, Ewen A Griffiths
INTRODUCTION: Cholecystectomy is one of the most common general surgical operations performed. Despite level one evidence supporting the role of cholecystectomy in the management of specific gallbladder diseases, practice varies between surgeons and hospitals. It is unknown whether these variations account for the differences in surgical outcomes seen in population-level retrospective data sets. This study aims to investigate surgical outcomes following acute, elective and delayed cholecystectomies in a multicentre, contemporary, prospective, population-based cohort...
2015: BMJ Open
Emmanuel A Aboh, Fatima J Giwa, A Giwa
BACKGROUND: Majority of the human population in semi-urban and urban areas in Nigeria are heavily reliant on well water as the main source of water supply for drinking and domestic use due to inadequate provision of potable pipe borne water. These groundwater sources can easily be fecally contaminated and thus, increase the incidence and outbreaks of preventable waterborne diseases. This study was carried out to determine the bacteriological quality of some well waters in Samaru, Z. MATERIALS AND METHODS: Samaru, Zaria located in Northern Nigeria, is a semi-urban university satellite town blessed with abundant ground and surface water...
January 2015: Annals of African Medicine
A Iu Razumovskiĭ, A V Degtiareva, N G Uskova, N V Kulikova, E V Feoktistova, V E Rachkov
UNLABELLED: Question of feasibility of laparoscopic Kasai procedure and laparoscopic hepaticojejunostomy for biliary atresia (the BA) and choledochal cysts (the CC) in children has been a subject of discussion for a long time and still remains unsolved. AIM: To improve the results of surgery for biliary tract malformations (the BTM) in children using laparoscopic technique. MATERIALS AND METHODS: The are 55 patients with BA and CC, who were performed endosurgical operations, and 37 patients, who were performed traditional open surgical procedures...
2014: Experimental & Clinical Gastroenterology
Nicola Gianotti, Andrea Poli, Massimo Galli, Angelo Pan, Giuliano Rizzardini, Alessandro Soria, Pierluigi Viale, Antonio Di Biagio, Tiziana Quirino, Paolo Viganò, Paolo Bonfanti, Antonella d'Arminio Monforte, Ida Fortino, Adriano Lazzarin
This study compared the cost-efficacy ratios of lopinavir/ritonavir monotherapy (LPV/r-MT) and of standard of care in virologically suppressed HIV-infected patients. The results of the efficacy and safety analyses are presented. We conducted a multicentre, randomised, open-label trial of HIV-infected adults on stable treatment, with HIV- RNA <50 copies/mL, randomised to continue the ongoing regimen (cART-arm) or to switch to LPV/r (400/100 mg BID) MT (MT-arm). Time to virological rebound (VR = confirmed HIV-RNA ?50 copies/mL) was estimated by Ka- plan-Meier method and changes in laboratory values during follow-up were evaluated by univariate mixed-linear models...
October 2014: New Microbiologica
Pedja Cuk, Mozammil Iqbal, Jakob Lykke
Acute acalculous cholecystitis is a rare condition associated with a high risk of gangrene, empyema and perforation of the gallbladder. In this case report it is described how hepatitis A infection leads to a fulminant perforated acalculous chole-cystitis, which is described sporadically in the literature. The patient presented in this case report had icterus and highly elevated liver enzymes. Magnetic resonance cholangiopan-crea-tography showed an acalculous gallbladder surrounded by free fluid. Laparoscopic cholecystectomy was performed due to sus-picion of perforated acute acalculous cholecystitis...
April 14, 2014: Ugeskrift for Laeger
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"