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Image-guided surgery

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https://www.readbyqxmd.com/read/28917285/fluorescence-imaging-agents-in-tumor-resection
#1
REVIEW
Walter Stummer, Eric Suero Molina
Intraoperative fluorescence imaging allows real-time identification of diseased tissue during surgery without being influenced by brain shift and surgery interruption. 5-Aminolevulinic acid, useful for malignant gliomas and other tumors, is the most broadly explored compound approved for fluorescence-guided resection. Intravenous fluorescein sodium has recently received attention, highlighting tumor tissue based on extravasation at the blood-brain barrier (defective in many brain tumors). Fluorescein in perfused brain, unselective extravasation in brain perturbed by surgery, and propagation with edema are concerns...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917256/postoperative-stereotactic-body-radiotherapy-for-spinal-metastases
#2
Majed Alghamdi, Chia-Lin Tseng, Sten Myrehaug, Pejman Maralani, Chris Heyn, Hany Soliman, Young Lee, Mark Ruschin, Leodante Da Costa, Victor Yang, Mikki Campbell, Arjun Sahgal
Spine is a common site of metastases in cancer patients. Spine surgery is indicated for select patients, typically those with mechanical instability and/or malignant epidural spinal cord (or cauda equina) compression. Although post-operative conventional palliative external beam radiation therapy has been the standard of care, technical improvements in radiation planning and image-guided radiotherapy have allowed for the application of stereotactic body radiotherapy (SBRT) to the spine. Spine SBRT is intended to ablate residual tumor and optimize local control by delivering several fold greater biologically effective doses...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28917255/stereotactic-body-radiotherapy-for-primary-renal-cell-carcinoma-and-adrenal-metastases
#3
Gargi Kothari, Alexander V Louie, David Pryor, Ian Vela, Simon S Lo, Bin S Teh, Shankar Siva
The incidence of renal cell carcinoma (RCC) and metastatic adrenal lesions continues to rise and present evolving complexities in terms of management. Technical challenges in treatment delivery are compounded by the setting of an ageing patient population with multiple medical co-morbidities. While the standard of care treatment for both primary RCC and oligometastatic adrenal lesions has typically been surgery, a number of patients may be medically or surgically inoperable, and for whom alternative options require consideration...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28905504/is-essential-tremor-a-single-entity
#4
Franziska Hopfner, Günther Deuschl
Essential tremor (ET) is a frequent movement disorder. A new tremor classification has subdivided ET, into the classical form with bilateral action tremor of the hands with or without involvement of further tremor locations and without any other explaining signs or symptoms for the tremor and into 'ET plus' which comes additionally with further neurologic signs of unknown origin. This will provide a better foundation for subclassifying the condition. The immediate cause of ET is a preformed oscillating network within the central nervous system as revealed with electrophysiologic methods...
September 14, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28895551/indocyanine-green-fluorescence-imaging-in-colorectal-surgery-overview-applications-and-future-directions
#5
REVIEW
Deborah S Keller, Takeaki Ishizawa, Richard Cohen, Manish Chand
Indocyanine green fluorescence imaging is a surgical tool with increasing applications in colorectal surgery. This tool has received acceptance in various surgical disciplines as a potential method to enhance surgical field visualisation, improve lymph node retrieval, and decrease the incidence of anastomotic leaks. In colorectal surgery specifically, small studies have shown that intraoperative fluorescence imaging is a safe and feasible method to assess anastomotic perfusion, and its use might affect the incidence of anastomotic leaks...
October 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28887861/ultrasound-guided-intratumoral-radiofrequency-ablation-coagulation-to-facilitate-meningioma-resection-preliminary-experience
#6
Li Yan, Junle Yang, Xiaodong Zhou, Guangbin He, Yu Zheng, Yali Zhu, Weiping Liu, Wen Luo, Haiying Qin, Haijing Liu, Xicai Yi, Yin Zhou
OBJECTIVES: This study aimed to explore the feasibility and safety of intratumoral radiofrequency ablation (RFA) in meningioma resection. METHODS: This study was approved by the Xijing Ethics Committee, and informed consent was obtained from all of the patients. Thirteen patients with meningiomas were recruited in the Neurosurgery Department of Xijing Hospital. These patients were treated with intratumoral RFA and surgery. We also chose 13 patients with meningiomas treated with traditional surgery as the control group...
September 9, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28887783/a-novel-integration-of-spectral-domain-optical-coherence-tomography-and-laser-ablation-system-for-precision-treatment
#7
Yingwei Fan, Boyu Zhang, Wei Chang, Xinran Zhang, Hongen Liao
PURPOSE: Complete resection of diseased lesions reduces the recurrence of cancer, making it critical for surgical treatment. However, precisely resecting residual tumors is a challenge during operation. A novel integrated spectral-domain optical-coherence-tomography (SD-OCT) and laser-ablation therapy system for soft-biological-tissue resection is proposed. This is a prototype optical integrated diagnosis and therapeutic system as well as an optical theranostics system. METHODS: We develop an optical theranostics system, which integrates SD-OCT, a laser-ablation unit, and an automatic scanning platform...
September 9, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28887681/pediatric-spine-imaging-post-scoliosis-surgery
#8
Alaa N Alsharief, Ron El-Hawary, Pierre Schmit
Many orthopedic articles describe advances in surgical techniques and implants used in pediatric scoliosis surgery. However, even though postoperative spine imaging constitutes a large portion of outpatient musculoskeletal pediatric radiology, few, if any, radiology articles discuss this topic. There has been interval advancement over the last decades of the orthopedic procedures used in the treatment of spinal scoliosis in adolescents with idiopathic scoliosis. The goal of treatment in these patients is to stop the progression of the curve by blocking the spinal growth and correcting the deformity as much as possible...
September 8, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28887645/pitfalls-in-soft-tissue-sarcoma-imaging-chronic-expanding-hematomas
#9
Kiarash Jahed, Behnaz Khazai, Monica Umpierrez, Ty K Subhawong, Adam D Singer
Solid or nodular enhancement is typical of soft tissue sarcomas although high grade soft tissue sarcomas and those with internal hemorrhage often appear heterogeneous with areas of nonenhancement and solid or nodular enhancement. These MRI findings often prompt an orthopedic oncology referral, a biopsy or surgery. However, not all masses with these imaging findings are malignant. We report the multimodality imaging findings of two surgically proven chronic expanding hematomas (CEH) with imaging features that mimicked sarcomas...
September 8, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28885120/threshold-of-the-extent-of-resection-for-who-grade-iii-gliomas-retrospective-volumetric-analysis-of-122-cases-using-intraoperative-mri
#10
Yu Fujii, Yoshihiro Muragaki, Takashi Maruyama, Masayuki Nitta, Taiichi Saito, Soko Ikuta, Hiroshi Iseki, Kazuhiro Hongo, Takakazu Kawamata
OBJECTIVE WHO Grade III gliomas are relatively rare and treated with multiple modalities such as surgery, chemotherapy, and radiotherapy. The impact of the extent of resection (EOR) on improving survival in patients with this tumor type is unclear. Moreover, because of the heterogeneous radiological appearance of Grade III gliomas, the MRI sequence that best correlates with tumor volume is unknown. In the present retrospective study, the authors evaluated the prognostic significance of EOR. METHODS Clinical and radiological data from 122 patients with newly diagnosed WHO Grade III gliomas who had undergone intraoperative MRI-guided resection at a single institution between March 2000 and December 2011 were analyzed retrospectively...
September 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28882499/secondary-surgical-management-of-osteoradionecrosis-using-three-dimensional-isodose-curve-visualization-a-report-of-three-cases
#11
J Kraeima, R J H M Steenbakkers, F K L Spijkervet, J L N Roodenburg, M J H Witjes
Osteoradionecrosis is defined as bone death secondary to radiotherapy. There is a relationship between the radiation dose received and the occurrence of osteoradionecrosis of the jaws, with the risk increasing above a dose of 60Gy. In cases of class III mandibular osteoradionecrosis, a segmental resection can be indicated. Current practice is to completely remove the affected bone up to the point where the bone looks healthy and is bleeding. Exact resection planning and the use of guided surgery based on imaging of the bone changes have not been reported so far...
September 4, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28881181/digital-workflow-for-computer-guided-implant-surgery-in-edentulous-patients-a-case-report
#12
Ji-Hyeon Oh, Xueyin An, Seung-Mi Jeong, Byung-Ho Choi
PURPOSE: The purpose of this article was to describe a fully digital workflow used to perform computer-guided flapless implant placement in an edentulous patient without the use of conventional impressions, models, or a radiographic guide. MATERIALS AND METHODS: Digital data for the workflow were acquired using an intraoral scanner and cone-beam computed tomography (CBCT). The image fusion of the intraoral scan data and CBCT data was performed by matching resin markers placed in the patient's mouth...
August 12, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28881160/effective-treatment-of-aggressive-fibromatosis-with-celecoxib-guided-by-genetic-testing
#13
Shanshan Yang, Xufu Wang, Haiping Jiang, Yongjie Wang, Zhuokun Li, Haijun Lu
Aggressive fibromatosis (AF) or desmoid tumors is an aggressive fibroblastic proliferation which is locally invasive but can not metastasize. The treatment of AF is challenging. Surgery was the main treatment modality for AF in the past, other strategies including radiotherapy, systemic therapies and wait-and-see policy. The use of non-steroidal anti-inflammatory drugs (NSAIDs) and targeted therapies has demonstrated good results. In the case report, a 39-year-old man presented with progressive chest wall pain...
September 7, 2017: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/28880999/stereo-eeg-diagnostic-and-therapeutic-tool-for-periventricular-nodular-heterotopia-epilepsies
#14
Laura Mirandola, Roberto F Mai, Stefano Francione, Veronica Pelliccia, Francesca Gozzo, Ivana Sartori, Lino Nobili, Francesco Cardinale, Massimo Cossu, Stefano Meletti, Laura Tassi
OBJECTIVE: Periventricular nodular heterotopias (PNHs) are malformations of cortical development related to neuronal migration disorders, frequently associated with drug-resistant epilepsy (DRE). Stereo-electroencephalography (SEEG) is considered a very effective step of the presurgical evaluation, providing the recognition of the epileptogenic zone (EZ). At the same time, via the intracerebral electrodes it is possible to perform radiofrequency thermocoagulation (SEEG-guided RF-TC) with the aim of ablating and/or disrupting the EZ...
September 7, 2017: Epilepsia
https://www.readbyqxmd.com/read/28875116/performance-of-robotic-assistance-for-skull-base-biopsy-a-phantom-study
#15
Jian-Hua Zhu, Jing Wang, Yong-Gui Wang, Meng Li, Yu-Xing Guo, Xiao-Jing Liu, Chuan-Bin Guo
Objectives  This study aims to evaluate the feasibility of a custom robot system guided by optical cone beam computed tomography (CBCT)-based navigation for skull base biopsy. Design  An accuracy study was conducted. Setting  Platform for navigation and robot-aided surgery technology. Participants  Phantom skull. Main Outcome Measures  The primary outcome measure was to investigate the accuracy of robot-assisted needle biopsy for skull base tumors. A 14-gauge needle was automatically inserted by the five degrees of freedom robot into the intended target, guided by optical navigation...
October 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28874046/intracellular-proteolytic-disassembly-of-self-quenched-nir-nanoparticles-turns-fluorescence-on-for-tumor-targeted-imaging
#16
Jinhui Jiang, Zhibin Zhao, Zijuan Hai, Hongyong Wang, Gaolin Liang
Design of tumor-targeting, intracellular protease-activatable near-infrared fluorescence (NIRF) nanoprobes is broadly interested but remains challenging. In this work, we report the rational design of a NIR probe Cys(StBu)-Lys(Biotin)-Lys-Lys(Cy5.5)-CBT (1) to facilely prepare the self-quenched nanoparticles 1-NPs for tumor-targeted imaging in vitro and in vivo. The biotinylated 1-NPs could be actively uptaken by biotin receptor-overexpressing tumor cells via receptor-mediated endocytosis. Upon intracellular proteolytic cleavage, 1-NPs were disassembled to yield the small molecular probe Lys(Cy5...
September 6, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28872754/contribution-of-virtual-biopsy-to-the-screening-of-microvascular-invasion-in-hepatocellular-carcinoma-a-pilot-study
#17
Nicolas Poté, François Cauchy, Miguel Albuquerque, Jérôme Cros, Olivier Soubrane, Pierre Bedossa, Valérie Paradis
BACKGROUND & AIMS: Microvascular invasion (mVI) is a major prognostic factor in hepatocellular carcinoma (HCC) that cannot be detected before surgery. Predictive biomarkers of mVI are thus urgently needed. We have developed an original approach of virtual biopsy to assess the performance of an immunohistochemical panel comprising three biomarkers of mVI (H4K16ac, H4K20me2, PIVKA-II) for the prediction of mVI in HCC core needle biopsies (CNB). METHODS: A test set of HCC surgical specimens (n=64) and an independent validation set of HCC CNB (n=42) were constituted...
September 5, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28872032/atlas-of-electroencephalography-3rd-edition
#18
Ali Akbar Asadi-Pooya, Dennis Dlugos, Christopher Skidmore, Michael R Sperling
Electroencephalography (EEG) is the recording of the electrical activity of the brain. EEG is a reliable test to assess cerebral function. It aids in diagnosis, classification, and management of patients with epilepsy. It also has practical uses in conditions other than epilepsy. Moreover, it is harmless and inexpensive. EEG is an important tool for evaluating patients with epilepsy. It may help classify the syndrome, identify the likely source of focal seizures, and confirm a diagnosis of status epilepticus...
September 5, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28871368/infected-multilocular-hydrocephalus-treated-by-rigid-and-flexible-endoscopes-with-electromagnetic-guided-neuronavigation-a-case-report
#19
Ryuji Ishizaki, Yuzuru Tashiro
BACKGROUND: Endoscopic surgery assisted by a navigation system has greatly aided treatment of infected multilocular hydrocephalus, especially in children. CASE REPORT: We describe a 2-year-old boy with multilocular hydrocephalus caused by repeated shunt infection, presenting with fever and vomiting. Magnetic resonance images (MRI) showed extraventricular cysts and severe ventricular deformity. There were three ventriculoperitoneal shunts and one residual ventricular catheter...
September 4, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28870824/spine-navigation-based-on-three-dimensional-robotic-fluoroscopy-for-accurate-percutaneous-pedicle-screw-placement-a-prospective-study-of-66-consecutive-cases
#20
Edward Fomekong, Salah Edine Safi, Christian Raftopoulos
BACKGROUND: Minimally invasive spine surgery is associated with obstructed visibility of anatomical landmarks and increased radiation exposure, leading to higher incidence of pedicle screw mispositioning. To address these drawbacks, intraoperative three-dimensional fluoroscopy (io3DF) and navigation are being increasingly used. We aimed to present our dedicated multifunctional hybrid operating room (HyOR) setup and evaluate the accuracy and safety of io3DF image-guided spinal navigation in transforaminal lumbar interbody fusion with percutaneous pedicle screw (PPS) placement...
September 1, 2017: World Neurosurgery
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