K N Lee, S S Neibart, A Droznin, C V Guthier, N E Martin, J D Mancias, M Lam, R Shiloh, L C Peng, K Ng, R Surana, P Enzinger, J Meyerhardt, H J Mamon
PURPOSE/OBJECTIVE(S): There has been increased interest in the use of short course hypofractionated radiotherapy as part of a total neoadjuvant treatment (TNT) approach in the management of rectal cancer since publication of the RAPIDO trial. However, the literature on short course radiation for rectal cancer has not reported significant acute toxicities in the weeks immediately following the completion of treatment. Anecdotally, a subset of patients has experienced acute neuropathic pain characterized in a lumbosacral distribution...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics