keyword
https://read.qxmd.com/read/38531800/the-value-of-combined-detection-of-serum-bnp-cardiac-troponin-i-and-dynamic-electrocardiogram-in-early-clinical-diagnosis-and-prognosis-of-patients-with-acute-myocardial-infarction
#1
JOURNAL ARTICLE
Qinxia Yu, Shuyan Yu
BACKGROUND: Acute myocardial infarction (AMI) is a prevalent cardiovascular disease resulting from myocardial ischemia and necrosis due to coronary artery occlusion. AMI is characterized by a sudden onset and high mortality, underscoring the significance of early diagnosis and treatment for improving patient prognosis. This study endeavors to assess the utility of a combined assessment involving serum brain natriuretic peptide (BNP), cardiac troponin-I (cTnI), and dynamic electrocardiogram (ECG) in the early clinical diagnosis and prognosis prediction of AMI...
March 2024: Discovery Medicine
https://read.qxmd.com/read/38525588/the-prognostic-value-of-visual-and-automatic-coronary-calcium-scoring-from-low-dose-ct-15o-water-pet
#2
JOURNAL ARTICLE
M M Dobrolinska, R A Jukema, S G M van Velzen, P A van Diemen, M J W Greuter, N H J Prakken, N R van der Werf, P G Raijmakers, R H J A Slart, P Knaapen, I Isgum, I Danad
PURPOSE: Firstly, to validate automatically and visually scored coronary artery calcium (CAC) on low dose CT (LDCT) scans with a dedicated calcium scoring CT (CSCT) scan. Secondly, to assess the added value of CAC scored from LDCT scans acquired during [15O]-water-PET myocardial perfusion imaging (MPI) on prediction of major adverse cardiac events (MACE). METHODS: 572 consecutive patients with suspected coronary artery disease, who underwent [15O]-water-PET MPI with LDCT and a dedicated CSCT scan were included...
March 25, 2024: European Heart Journal Cardiovascular Imaging
https://read.qxmd.com/read/38524037/altered-mental-status-in-the-setting-of-thrombotic-thrombocytopenic-purpura-ttp-and-spontaneous-coronary-artery-dissection-scad-a-case-report-and-literature-review
#3
Esmirna Perez, Nehemias Guevara, Jordan Smith, Ricardo Velasquez
Altered mental status (AMS) is a common condition encountered in daily practice. Finding the cause is essential for treatment, but sometimes this may be challenging. Spontaneous coronary artery dissection (SCAD) is frequently underdiagnosed and is a potentially fatal cause of acute coronary syndrome. Clinical presentation depends on the extent of SCAD, ranging from unstable angina to sudden death. AMS has not been reported with this condition, but it may be possible in hypoperfusion states. Thrombotic thrombocytopenic purpura (TTP) is part of the microangiopathic hemolytic anemia (MAHA) spectrum, presenting with AMS as the cardinal symptom...
February 2024: Curēus
https://read.qxmd.com/read/38518006/causal-association-of-tsh-with-ischemic-heart-diseases-and-heart-failure-a-2-sample-mendelian-randomization-study
#4
JOURNAL ARTICLE
Yuan Gao, Tianwei Zhan, Yingchun Xu, Kaijun Zhu, Yifei Shi, Langping Jin, Liwei Meng
Thyroid dysfunction is associated with the risk of cardiovascular disease; however, whether plasma thyroid-stimulating hormone (TSH) levels in subjects with euthyroidism affect the risk of cardiovascular disease remains unclear. This study aimed to investigate the causal association between plasma TSH levels and cardiovascular diseases, particularly ischemic heart disease and heart failure (HF). Summary statistics from the Integrative Epidemiology Unit Open genome-wide association studies Project and FinnGen consortium were used to investigate the causal relationship between plasma TSH levels and the risk of cardiovascular diseases...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38508987/effects-of-remote-ischaemic-conditioning-in-stable-and-unstable-angina-patients-undergoing-percutaneous-coronary-intervention-a-systematic-review-and-meta-analysis
#5
REVIEW
Wilbert Huang, Alvin Frederich, Alizha Rochana Putri
AIM: Type 4a myocardial infarction (T4aMI), defined as myocardial injury associated with percutaneous coronary intervention (PCI), is associated with a poor prognosis and there is conflicting evidence regarding the effectiveness of remote ischaemic conditioning (RIC) in its prevention. This review aimed to determine the effect of RIC on stable and unstable angina patients. METHOD: A systematic review was conducted in PubMed and Central database. Outcome measures were: changes in peak troponin, creatine kinase myocardial band (CKMB), C-reactive protein (CRP) level, incidence of T4aMI, and major adverse cardiovascular event (MACE)...
March 19, 2024: Heart, Lung & Circulation
https://read.qxmd.com/read/38503613/efficacy-and-safety-of-tongxin-formula-after-stent-implantation-for-acute-coronary-syndrome-a-multicenter-double-blind-placebo-controlled-randomized-trial
#6
JOURNAL ARTICLE
Wen Zhu, Su Wang, Lei Zhang, Feng-Qun Xie, Jie Cheng, Xian-Kai Li, Wei Chen, Shi-Yun Yan, Qi-Mao Feng
OBJECTIVE: The aim of this study is to comprehensively evaluate both the efficacy and safety profile of integrating the Tongxin formula with optimal medical therapy (OMT) for patients experiencing acute coronary syndromes subsequent to coronary stenting, over the course of one year. METHODS: We enrolled 150 patients diagnosed with acute coronary syndromes who had received stent placement within one month and exhibited a TCM syndrome characterized by Qi deficiency and blood stasis...
March 1, 2024: Explore: the Journal of Science and Healing
https://read.qxmd.com/read/38495410/timing-percutaneous-coronary-interventions-and-cardiovascular-events-in-non-st-elevation-myocardial-infarction-patients
#7
JOURNAL ARTICLE
Rouhollah Hemmati, Mobina Fathi, Morteza Heidarian Moghadam, Bahram Mohebbi, Kambiz Keshavarz, Ahmad Mohebbi, Asghar Rahmani
BACKGROUND: The timing of coronary angiography in patients with non-ST elevation myocardial infarction (NSTEMI) needs to be well defined. In this study, based on the timing of percutaneous coronary intervention (PCI), we evaluated the incidence of major adverse cardiovascular events (MACE) in NSTEMI patients. METHODS: In this longitudinal study, we included 156 NSTEMI patients who underwent a PCI at three time points, including <12 hr. (n = 53), 12-24 hr. (n = 54), and ≥24 hr...
2024: American Journal of Cardiovascular Disease
https://read.qxmd.com/read/38492858/autoimmune-blistering-disorders-and-cardiovascular-risks-a-population-based-cohort-study
#8
JOURNAL ARTICLE
Kasper Bonnesen, Christian F B Poulsen, Sigrun A J Schmidt, Henrik T Sørensen, Morten Schmidt
BACKGROUND: Autoimmune blistering disorders (ABDs) might elevate cardiovascular risk, but studies are lacking. OBJECTIVE: To examine if ABDs elevate the risk of atherosclerotic cardiovascular disease (ASCVD), heart failure, arrhythmia, venous thromboembolism, and cardiovascular death. METHODS: A population-based cohort of Danish patients with ABD (≥18 years of age) diagnosed during 1996-2021 (n=3,322) was compared with an age and sex-matched comparison cohort from the general population (n=33,195)...
March 14, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38485210/effectiveness-of-polypill-for-primary-and-secondary-prevention-of-cardiovascular-disease-a-pragmatic-cluster-randomised-controlled-trial-polypars
#9
JOURNAL ARTICLE
Fatemeh Malekzadeh, Abdullah Gandomkar, Hossein Poustchi, Arash Etemadi, Gholamreza Roshandel, Armin Attar, Firoozeh Abtahi, Shahrokh Sadeghi Boogar, Vahid Mohammadkarimi, Mohammad Reza Fattahi, Abbas Mohagheghi, Reza Malekzadeh, Sadaf G Sepanlou
BACKGROUND: We aimed to investigate the effectiveness of fixed-dose combination therapy (polypill) for primary and secondary prevention of major cardiovascular diseases in a typical rural setting. METHODS: The PolyPars Study is a two-arm pragmatic cluster-randomised trial nested within the PARS cohort study, including all residents aged over 50 years in the entire district in southern Iran. The 91 villages underwent random allocation into two arms: the control arm, encompassing 45 clusters, was subjected to non-pharmacological intervention (educational training on healthy lifestyle), whereas the intervention arm, comprising 46 clusters, received the non-pharmacological interventions in conjunction with a once-daily polypill tablet...
March 14, 2024: Heart
https://read.qxmd.com/read/38482842/pemafibrate-and-other-triglyceride-lowering-therapies-to-reduce-risk-of-cardiovascular-and-metabolic-disease
#10
JOURNAL ARTICLE
Michael Miller
PURPOSE OF REVIEW: Although high triglycerides are consistently associated with elevated risk of cardiovascular disease (CVD), therapies that reduce triglyceride levels have inconsistently translated into reduced CVD risk. RECENT FINDINGS: To date, three clinical trials have tested triglyceride-lowering therapies in patients with hypertriglyceridemia (HTG) and elevated risk of incident/recurrent CVD. In REDUCE-IT (Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial), assignment to IPE, a highly purified eicosapentanoic acid (EPA), resulted in a 25% reduction in nonfatal myocardial infarction), nonfatal stroke, cardiovascular death, coronary revascularization and hospitalization for unstable angina...
March 6, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38476976/impact-of-diabetes-mellitus-and-triglyceride-glucose-index-on-mortality-and-cardiovascular-outcomes-in-patients-with-chronic-coronary-syndrome-undergoing-coronary-computed-tomography-angiography
#11
JOURNAL ARTICLE
Kenichiro Otsuka, Hiroki Yamaura, Kenei Shimada, Takatoshi Sugiyama, Kana Hojo, Hirotoshi Ishikawa, Yasushi Kono, Noriaki Kasayuki, Daiju Fukuda
BACKGROUND: There is limited knowledge regarding whether an elevated triglyceride glucose (TyG) index can serve as a prognostic marker for mortality and cardiovascular outcomes, independent of diabetes mellitus (DM) and plaque burden, in patients with chronic coronary syndrome (CCS). METHODS: Patients with CCS (n = 684) were categorized into subgroups based on the presence of DM, and patients without DM were further divided into two groups based on presence or absence of an elevation of TyG index >8...
March 2024: Int J Cardiol Cardiovasc Risk Prev
https://read.qxmd.com/read/38467788/the-new-esc-acute-coronary-syndrome-guideline-and-its-impact-in-the-cpu-and-emergency-department-setting
#12
REVIEW
Martin Möckel
The new guideline on acute coronary syndrome (ACS) of the European Society of Cardiology (ESC) replaces two separate guidelines on ST-elevation myocardial infarction (STEMI) and non-ST-elevation (NSTE) ACS. This change of paradigm reflects the experts view that the ACS is a continuum, starting with unstable angina and ending in cardiogenic shock or cardiac arrest due to severe myocardial ischemia. Secondary, partly non-atherosclerotic-caused myocardial infarctions ("type 2") are not integrated in this concept...
March 11, 2024: Herz
https://read.qxmd.com/read/38459625/testosterone-therapy-in-females-is-not-associated-with-increased-cardiovascular-or-breast-cancer-risk-a-claims-database-analysis
#13
JOURNAL ARTICLE
Pranjal Agrawal, Sajya M Singh, Jessica Hsueh, Aurora Grutman, Clemens An, Corey Able, Una Choi, Jaden Kohn, Marisa Clifton, Taylor P Kohn
BACKGROUND: Testosterone therapy (TTh) has been shown to improve libido in women with sexual dysfunction, but its utilization has been limited due to concern for cardiovascular events and past studies reporting highly variable results. AIM: To assess the association of TTh in women with major adverse cardiac events (MACEs), including heart attack, stroke, or death, using a large database. METHODS: The TriNetX Diamond Network was queried from 2009 to 2022...
March 8, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38457555/in-hospital-initiation-of-a-pcsk9-inhibitor-in-patients-with-acute-coronary-syndrome-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
JOURNAL ARTICLE
Wenhai Shi, Yong Xu, Lin Zhou, Wuwan Wang, Wei Huang, Bo Zhou
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been shown to be effective and safe in patients with stable angina and previous myocardial infarction. However, evidence for initiating their use in patients hospitalized with acute coronary syndrome (ACS) is limited. This systematic review and meta-analysis was performed to provide more clinical evidence. METHODS: PubMed, Embase, OVID, Cochrane Library and ClinicalTrials.gov were systematically searched for eligible randomized controlled trials up to March 20, 2023...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38456877/ai-defined-cardiac-anatomy-improves%C3%A2-risk-stratification-of-hybrid%C3%A2-perfusion-imaging
#15
JOURNAL ARTICLE
Robert J H Miller, Aakash Shanbhag, Aditya Killekar, Mark Lemley, Bryan Bednarski, Paul B Kavanagh, Attila Feher, Edward J Miller, Timothy Bateman, Valerie Builoff, Joanna X Liang, David E Newby, Damini Dey, Daniel S Berman, Piotr J Slomka
BACKGROUND: Computed tomography attenuation correction (CTAC) improves perfusion quantification of hybrid myocardial perfusion imaging by correcting for attenuation artifacts. Artificial intelligence (AI) can automatically measure coronary artery calcium (CAC) from CTAC to improve risk prediction but could potentially derive additional anatomic features. OBJECTIVES: The authors evaluated AI-based derivation of cardiac anatomy from CTAC and assessed its added prognostic utility...
March 6, 2024: JACC. Cardiovascular Imaging
https://read.qxmd.com/read/38452813/prognostic-values-of-syntax-score-ii-in-patients-with-coronary-artery-disease-undergoing-percutaneous-coronary-intervention-cohort-study
#16
JOURNAL ARTICLE
Santhosh Satheesh, Ritesh Kumar, Ajith Ananthakrishna Pillai, Raja Selvaraj, Sreekumaran Nair, Dhivya Priya
BACKGROUND: The data on prognostic values of SYNTAX score II in patients undergoing percutaneous coronary intervention is limited. We report predictive utility of SYNTAX score II in relation to in hospital and 1 year mortality of the patients undergoing percutaneous coronary intervention. METHODS: This was a cohort study of patients who underwent percutaneous coronary intervention (PCI) at a single centre from January 2018 to December 2019. In hospital and 12-month events and mortality was analysed among 1000 patients...
March 5, 2024: Indian Heart Journal
https://read.qxmd.com/read/38446028/retrieval-of-a-severely-double-kinked-catheter-in-the-right-brachial-artery-by-internal-fixation-with-a-peripheral-angioplasty-balloon
#17
JOURNAL ARTICLE
Kewel Kanabar, Rujuta Parikh, Pooja Vyas, Vishal Sharma, Apoorva M
A 55-year-old female patient with unstable angina and accelerated hypertension was planned for invasive coronary and renal angiogram.
February 29, 2024: Journal of Invasive Cardiology
https://read.qxmd.com/read/38444364/outcomes-by-sex-in-the-international-study-of-comparative-health-effectiveness-with-medical-and-invasive-approaches-ischemia-trial
#18
JOURNAL ARTICLE
Mario Gaudino, John H Alexander, Sigrid Sandner, Lamia Harik, Jessica Kim, Gregg W Stone, Mohamed Rahouma, Patrick O'Gara, Deepak L Bhatt, Bjorn Redfors
BACKGROUND: In the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial, among participants with stable coronary artery disease, the risk of cardiac events was similar between an invasive (INV) strategy of angiography and coronary revascularisation and a conservative (CON) strategy of initial medical therapy alone. Outcomes according to participant sex were not reported. AIMS: We aimed to analyse the outcomes of ISCHEMIA by participant sex...
March 5, 2024: EuroIntervention
https://read.qxmd.com/read/38441990/the-use-of-a-homemade-bag-repositioning-system-to-salvage-complete-coronary-stent-dislodgement
#19
JOURNAL ARTICLE
Siu-Fung Wong, Tak-Shun Chung
A 71-year-old man who had undergone percutaneous transluminal coronary angioplasty (PTCA) in 2013 was admitted for unstable angina.
March 2024: Journal of Invasive Cardiology
https://read.qxmd.com/read/38433430/retrospective-review-of-non-st-segment-elevation-acute-coronary-syndrome-presenting-to-the-emergency-department-of-a-major-tertiary-center-in-saudi-arabia
#20
JOURNAL ARTICLE
Muhammad Nauman Qureshi, Eman Nayaz Ahmed, Khaled Abdulrahman Ahmed, Eyad Bashtawi
BACKGROUND: Acute coronary syndrome (ACS) comprises a spectrum of diseases ranging from unstable angina (UA), non-ST elevation myocardial infarction (non-STEMI) and ST elevation myocardial infarction (STEMI). Treatment of ACS without STEMI (NSTEMI-ACS) can vary, depending on the severity of presentation and multiple other factors. OBJECTIVE: Analyze the NSTEMI-ACS patients in our institution. DESIGN: Retrospective observational. SETTING: A tertiary care institution with accredited chest pain center...
2024: Annals of Saudi Medicine
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