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Altruistic Donor

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https://www.readbyqxmd.com/read/28610845/hemochromatosis-and-blood-donation
#1
REVIEW
Turid Aarhus Braseth, Tor Hervig, Anne Synnove Rosvik
The voluntary, unpaid, altruistic blood donor is a cornerstone of current transfusion medicine. The complexity of medical and ethical issues related to blood donation and hemochromatosis has led to a large number of studies related to the safety of the hemochromatosis donor and the quality of the blood components produced from these donations. The issue of accepting persons with HC as blood donors is diverting, both in Europe and worldwide and without joint guidelines. A questionnaire-based study was performed and mailed to all 25 blood bank leaders in Norway...
May 18, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28596416/a-kidney-graft-survival-calculator-that-accounts-for-mismatches-in-age-sex-hla-and-body-size
#2
Valarie B Ashby, Alan B Leichtman, Michael A Rees, Peter X-K Song, Mathieu Bray, Wen Wang, John D Kalbfleisch
BACKGROUND AND OBJECTIVES: Outcomes for transplants from living unrelated donors are of particular interest in kidney paired donation (KPD) programs where exchanges can be arranged between incompatible donor-recipient pairs or chains created from nondirected/altruistic donors. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using Scientific Registry of Transplant Recipients data, we analyzed 232,705 recipients of kidney-alone transplants from 1998 to 2012. Graft failure rates were estimated using Cox models for recipients of kidney transplants from living unrelated, living related, and deceased donors...
June 8, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28579040/autonomy-and-self-esteem-of-women-who-donate-to-an-oocyte-cryopreservation-bank-in-the-netherlands
#3
Marjolein R Bakker, Joyce Maas, Marrie H Bekker, Annelien L Bredenoord, Bart C Fauser, Annelies M Bos
Worldwide, oocyte donors donate voluntarily or receive varying amounts of money for donation. This raises ethical questions regarding the appropriateness of financial compensation, and the possibility of undue inducement and exploitation of oocyte donors. Are these donors capable of making an independent, well-considered decision? Regarding this matter, it is important to examine aspects such as autonomy-connectedness and self-esteem. In this cross-sectional study, demographic characteristics and donation motivations were assessed in 92 women who attended the University Medical Center (UMC) Utrecht as potential oocyte donors between June 2012 and July 2016...
May 17, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28574902/advanced-donation-programs-and-deceased-donor-initiated-chains-2-innovations-in-kidney-paired-donation
#4
Anji E Wall, Jeffrey L Veale, Marc L Melcher
Kidney paired donation strategies have facilitated compatible living-donor kidney transplants for end stage renal disease patients with willing but incompatible living donors. Success has inspired further innovations that expand opportunities for kidney-paired donation. Two such innovations are the advanced donation strategy in which a donor provides a kidney before their recipient is matched, or even in need of, a kidney transplant, and deceased donor initiated chains in which chains are started with deceased donors rather than altruistic living donors...
June 1, 2017: Transplantation
https://www.readbyqxmd.com/read/28507916/past-present-and-future-of-kidney-paired-donation-transplantation-in-india
#5
REVIEW
Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Pranjal R Modi, Veena R Shah, Sayyed J Rizvi, Bipin C Pal, Manisha P Modi, Priya S Shah, Umesh T Varyani, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Minaxi H Patel, Varsha B Trivedi, Hargovind L Trivedi
One third of healthy willing living kidney donors are rejected due to ABO blood group incompatibility and donor specific antibody. This increases pre-transplant dialysis duration leading to increased morbidity and mortality on the kidney transplantation waiting list. Over the last decade kidney paired donation is most rapidly increased source of living kidney donors. In a kidney transplantation program dominated by living donor kidney transplantation, kidney paired donation is a legal and valid alternative strategy to increase living donor kidney transplantation...
April 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28486981/patients-willingness-to-pay-for-the-treatment-of-tuberculosis-in-nigeria-exploring-own-use-and-altruism
#6
Ogbonnia G Ochonma, Obinna E Onwujekwe
BACKGROUND: Although, current treatment services for Tuberculosis (TB) in Nigeria are provided free of charge in public facilities, the benefits (value) that patients attach to such service is not known. In addition, the prices that could be charged for treatment in case government and its partners withdraw from the provision of free services or inclusion of the services in health insurance plans are not known. Hence, there is a need to elicit the maximum amounts that patients are willing to pay for TB treatment services, both for themselves and for the very poor patients that may not be able to pay if some user fees are introduced (altruistic willingness to pay)...
May 10, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28443056/concerns-mental-health-and-quality-of-life-in-living-kidney-donation-parent-donor-candidates-worry-less-about-themselves
#7
M Ángeles Pérez-San-Gregorio, Agustín Martín-Rodríguez, Asunción Luque-Budia, Rupert Conrad
Even though the majority of living kidney donor candidates appear in good mental health and show few concerns little is known concerning the influence of the type of donor-recipient relationship on donor candidates' specific concerns with regard to kidney donation. 136 donor candidates at Virgen del Rocío University Hospital of Seville filled in the Scale of Concerns Regarding Living Kidney Donation of whom 105 donor candidates and their corresponding recipients (105 patients with End-Stage Renal Disease) were further evaluated with regard to mental health (Hospital Anxiety and Depression Scale, Beck Depression Inventory-II) and quality of life (SF-36 Health Survey)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28342273/characteristics-of-compatible-pair-participants-in-kidney-paired-donation-at-a-single-center
#8
Francis L Weng, Tracy Grogan, Anup M Patel, Shamkant Mulgaonkar, Marie M Morgievich
Compatible pairs of living kidney donors and their intended recipients can enter into kidney paired donation (KPD) and facilitate additional living donor kidney transplants (LDKTs). We examined 11 compatible pairs (the intended recipients and their intended, compatible donors) who participated in KPD, along with the recipients' 11 matched, exchange donors. The 11 pairs participated in 10 separate exchanges (three were multicenter exchanges) that included 33 total LDKTs (22 additional LDKTs). All the intended donors were blood group O and female, with a mean living kidney donor profile index (LKDPI) of 27...
March 25, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28264142/using-body-donor-demographics-to-assist-the-implementation-of-donation-programs-in-brazil
#9
Andrea Oxley da Rocha, Deivis de Campos, Marco Aurélio Farina, Gabriel Sartori Pacini, Marina Cornelli Girotto, Arlete Hilbig
The use of human material in anatomy education depends upon the generosity of body donors. However, little is known regarding the demographics of body donors in Brazil, where voluntary body donation is a relatively rare phenomenon. Hence, the aim of the present study was to elucidate the demographic profile of applicants to the Body Donation Program (BDP) at the Federal University of Health Sciences of Porto Alegre in Brazil, as well as to assess whether the observed characteristics of body donors are unique to that sample, or if they merely reflect the characteristics of the regional population...
March 6, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28202136/foreign-aid-allocation-from-a-network-perspective-the-effect-of-global-ties
#10
Liam Swiss
This article examines competing explanations for foreign aid allocation on the global level and argues for a new approach to understanding aid from an institutionalist perspective. Using network data on all official bilateral aid relationships between countries in the period from 1975 through 2006 and data on recipient country ties to world society, the article offers an alternative explanation for the allocation of global foreign aid. Fixed effects negative binomial regression models on a panel sample of 117 developing countries reveal that global ties to world society in the form of non-governmental memberships and treaty ratifications are strong determinants of the network centrality of recipient countries in the global foreign aid network...
March 2017: Social Science Research
https://www.readbyqxmd.com/read/28136000/altruism-or-obligation-the-motivations-and-experience-of-women-who-donate-oocytes-to-known-recipients-in-assisted-conception-treatment-an-interpretative-phenomenological-analysis-study
#11
Santanu Acharya, Louise Bryant, Maureen Twiddy
INTRODUCTION: This qualitative study was conducted to explore the motivations and experience of oocyte donors donating to women known to them. METHODS: Three women who donated oocytes to a close relative were interviewed and data were analysed using an Interpretative Phenomenological Analysis approach. RESULTS: The two key elements noted were "motivations for donation" and "coping with the consequences of oocyte donation". The motivation for donation was influenced by the familial bond that was strengthened by the donation process in some cases...
March 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28088240/feasibility-of-an-altruistic-sperm-donation-program-in-canada-results-from-a-population-based-model
#12
Daria O'Reilly, James M Bowen, Kuhan Perampaladas, Riaz Qureshi, Feng Xie, Edward Hughes
BACKGROUND: Stringent donor-screening criteria and legislation prohibiting payment for donor gametes have contributed to the radical decline of donor insemination (DI) using sperm provided by Canadian men. Thus, many individuals rely on imported sperm. This paper examines the feasibility of an altruistic sperm donation (ASD) program to meet the needs of Canadians. METHODS: Using Canadian census data, published literature and expert opinions, two population-based, top-down mathematical models were developed to estimate the supply and demand for donor sperm and the feasibility of an ASD program...
January 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28079112/microbes-can-help-explain-the-evolution-of-host-altruism
#13
Ohad Lewin-Epstein, Ranit Aharonov, Lilach Hadany
The evolution of altruistic behaviour, which is costly to the donor but beneficial for the recipient, is among the most intriguing questions in evolutionary biology. Several theories have been proposed to explain it, including kin selection, group selection and reciprocity. Here we propose that microbes that manipulate their hosts to act altruistically could be favoured by selection, and may play a role in the widespread occurrence of altruism. Using computational models, we find that microbe-induced altruism can explain the evolution of host altruistic behaviour under wider conditions than host-centred theories, including in a fully mixed host population, without repeating interactions or individual recognition...
January 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/27854130/donor-insemination-israel-as-a-representative-case-of-a-competitive-market-examining-the-possibility-of-policy-reform
#14
Limor D Gonen
AIM: To measure the private and social benefits of donor insemination (DI). METHODS: An empirical model investigates the general public and DI clients' willingness to pay (WTP) for DI, and the willingness of potential donors to become altruistic or paid sperm donors. RESULTS: The general public and DI clients value DI and have a positive WTP for it, whereas willingness to donate, altruistically or for payment, is either low or very low. CONCLUSION: The general public's and DI clients' WTP for DI is in average above actual cost, so the government should consider funding or subsidizing DI...
November 17, 2016: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/27570751/impact-of-donor-source-on-the-outcome-of-live-donor-kidney-transplantation-a-single-center-experience
#15
Yasser Elsayed Matter, Ayman M Nagib, Omar E Lotfy, Ahmed Maher Alsayed, Ahmed F Donia, Ayman F Refaie, Ahmed I Akl, Mohamed Hamed Abbas, Mohammed M Abuelmagd, Hussein A Shaeashaa, Ahmed A Shokeir
BACKGROUND: Renal transplantation is the ideal method for management of end-stage renal disease. The use of living donors for renal transplantation was critical for early development in the field and preceded the use of cadaveric donors. Most donors are related genetically to the recipients, like a parent, a child, or a sibling of the recipient, but there are an increasing percentage of cases where donors are genetically unrelated like spouses, friends, or altruistic individuals. Donor shortages constitute the major barrier for kidney transplantation, and much effort has been made to increase the supply of living donors...
May 2016: Nephro-urology Monthly
https://www.readbyqxmd.com/read/27412344/online-sperm-donation-a-survey-of-the-demographic-characteristics-motivations-preferences-and-experiences-of-sperm-donors-on-a-connection-website
#16
T Freeman, V Jadva, E Tranfield, S Golombok
STUDY QUESTION: What are the demographic characteristics, motivations, preferences and experiences of heterosexual, gay and bisexual sperm donors on a connection website (i.e. a website that facilitates direct contact between donors and recipients of gametes)? SUMMARY ANSWER: This demographically diverse group of men was donating for altruistic reasons and perceived the website as providing greater choice over donation arrangements: approximately one third favoured anonymous donation, most of whom were heterosexual, whilst gay and bisexual donors were more likely to be in contact with children conceived with their sperm...
September 2016: Human Reproduction
https://www.readbyqxmd.com/read/27343721/medical-students-knowledge-familiarity-and-attitudes-towards-hematopoietic-stem-cell-donation-stem-cell-donation-behaviors
#17
Praveena Narayanan, Alexandra Wolanskyj, Shawna L Ehlers, Mark R Litzow, Mrinal S Patnaik, William J Hogan, Shahrukh K Hashmi
Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for patients with blood disorders and genetic diseases. Approximately 70% of the HSCTs currently performed in the United States use stems cells from an unrelated donor who donated voluntarily. Medical students (MS) are a young, diverse, influential population whose willingness to engage in altruistic acts, such as donating stem cells, may be correlated with knowledge on the topic. A literature gap exists in MS perspectives towards HSCT and the bone marrow registry (BMR) and prior studies suggest that misconceptions about donation deter MS from participation on the BMR, which may decrease opportunities to educate other potential donors...
September 2016: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27293985/motivating-factors-and-potential-deterrents-to-blood-donation-in-high-school-aged-blood-donors
#18
Rachel Finck, Alyssa Ziman, Matthew Hoffman, Michelle Phan-Tang, Shan Yuan
Background. To ensure an adequate supply of blood, collection centers must design campaigns that successfully recruit and maintain an active donor pool. Understanding factors that motivate and deter individuals from donating may help centers develop targeted recruitment campaigns. These factors among high school aged blood donors have not yet been fully investigated. Study Design and Methods. A voluntary, anonymous survey was administered to student donors at high school mobile blood drives. The survey instrument asked the students to rate several potential motivating factors in their importance in the decision to donate blood and several potential deterring factors in their future decision whether or not to donate blood again...
2016: Journal of Blood Transfusion
https://www.readbyqxmd.com/read/27270455/indirect-fitness-benefits-enable-the-spread-of-host-genes-promoting-costly-transfer-of-beneficial-plasmids
#19
Tatiana Dimitriu, Dusan Misevic, Chantal Lotton, Sam P Brown, Ariel B Lindner, François Taddei
Bacterial genes that confer crucial phenotypes, such as antibiotic resistance, can spread horizontally by residing on mobile genetic elements (MGEs). Although many mobile genes provide strong benefits to their hosts, the fitness consequences of the process of transfer itself are less clear. In previous studies, transfer has been interpreted as a parasitic trait of the MGEs because of its costs to the host but also as a trait benefiting host populations through the sharing of a common gene pool. Here, we show that costly donation is an altruistic act when it spreads beneficial MGEs favoured when it increases the inclusive fitness of donor ability alleles...
June 2016: PLoS Biology
https://www.readbyqxmd.com/read/27263265/bartering-for-a-compatible-kidney-using-your-incompatible-live-kidney-donor-legal-and-ethical-issues-related-to-kidney-chains
#20
Evelyn M Tenenbaum
Kidney chains are a recent and novel method of increasing the number of available kidneys for transplantation and have the potential to save thousands of lives. However, because they are novel, kidney chains do not fit neatly within existing legal and ethicalframeworks, raising potential barriers to their full implementation. Kidney chains are an extension of paired kidney donation, which began in the United States in 2000. Paired kidney donations allow kidney patients with willing, but incompatible, donors to swap donors to increase the number of donor/recipient pairs and consequently, the number of transplants...
2016: American Journal of Law & Medicine
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