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Susan E Luczak, Rubin Khoddam, Sheila Yu, Tamara L Wall, Anna Schwartz, Steve Sussman
BACKGROUND AND OBJECTIVES: We conducted a review of the prevalence and co-occurrence of 12 types of addictions in US ethnic/racial groups and discuss the implications of the results for genetic research on addictions. METHODS: We utilized MEDLINE and PsycINFO databases to review the literature on alcohol, tobacco, marijuana, illicit drugs, gambling, eating/food, internet, sex, love, exercise, work, and shopping. We present results for each addiction based on total US prevalence, prevalence within ethnic groups, and co-occurrence of addictions among ethnic groups when available...
October 19, 2016: American Journal on Addictions
R Rebecca Love, Aaron M Steele, Mamadou B Coulibaly, Sékou F Traore, Scott J Emrich, Michael C Fontaine, Nora J Besansky
The molecular mechanisms and genetic architecture that facilitate adaptive radiation of lineages remain elusive. Polymorphic chromosomal inversions, due to their recombination-reducing effect, are proposed instruments of ecotypic differentiation. Here we study an ecologically diversifying lineage of An. gambiae, known as the Bamako chromosomal form based on its unique complement of three chromosomal inversions, to explore the impact of these inversions on ecotypic differentiation. We used pooled and individual genome sequencing of Bamako, typical (non-Bamako) An...
October 19, 2016: Molecular Ecology
Kirsten C Odegard, Robert Vincent, Rahul G Baijal, Suanne M Daves, Robert G Gray, Alexander J Javois, Barry A Love, Philip Moore, David Nykanen, Lori Q Riegger, Scott G Walker, Elizabeth C Wilson
Current practice of sedation and anesthesia for patients undergoing pediatric and congenital cardiac catheterization laboratory (PCCCL) procedures is known to vary among institutions, a multi-society expert panel with representatives from the Congenital Heart Disease Council of the Society for Cardiovascular Angiography and Interventions, the Society for Pediatric Anesthesia and the Congenital Cardiac Anesthesia Society was convened to evaluate the types of sedation and personnel necessary for procedures performed in the PCCCL...
October 3, 2016: Anesthesia and Analgesia
(no author information available yet)
'Let's liberate the term tender loving care from its end of life connotations and see if love, as the essential ingredient that influences the "how" of what we do, can be a guiding principle to good management and quality improvement'.
September 14, 2016: Nursing Standard
Kenan Karbeyaz, Mehmet Toygar, Adnan Çelikel
INTRODUCTION: In this study student suicides are classified as a distinct group in Eskisehir-a city located in the western part of our country and famous as a student city. The study aims at describing demographic and suicide specification of cases and compare some important issues between males and females. METHOD: All the judicially deaths in Eskisehir in a 12 year period between 2004 and 2015 have been evaluated. 75 cases that were deemed as suicide cases as a result of criminal investigation have been included in the study...
September 28, 2016: Journal of Forensic and Legal Medicine
Brittani Crook, Brad Love
The young adult (YA) cancer community represents an understudied population in interpersonal and health communication scholarship. Through qualitative analysis, this study sought to advance a dark side perspective by exploring the content of messages shared in an online support forum for YAs with cancer. Our findings highlight a variety of complexities YAs face in an online cancer support community, including the light and dark of soliciting support, disclosing to a community, advocacy online, negative sentiment evaluating health care services, and asynchronous communication...
October 14, 2016: Qualitative Health Research
Eleftheria Kalogera, Jamie N Bakkum-Gamez, Amy L Weaver, James P Moriarty, Bijan J Borah, Carrie L Langstraat, Christopher J Jankowski, Jenna K Lovely, William A Cliby, Sean C Dowdy
OBJECTIVE: To investigate opioid use and pain scores associated with incisional injection of liposomal bupivacaine compared with bupivacaine hydrochloride after laparotomy for gynecologic malignancies. METHODS: A retrospective cohort study was conducted to compare abdominal incision infiltration with liposomal bupivacaine with bupivacaine hydrochloride after modification of a pre-existing enhanced recovery pathway. Patients undergoing staging laparotomy or complex cytoreductive surgery under the updated pathway were compared with patients treated under the original pathway (historic controls)...
October 6, 2016: Obstetrics and Gynecology
Sandra G Sosa-Rubi, Biani Saavedra-Avendano, Claudia Piras, S Janae Van Buren, Sergio Bautista-Arredondo
Dating violence is a significant problem in Mexico. National survey data estimated 76 % of Mexican youth have been victims of psychological aggression in their relationships; 15.5 % have experienced physical violence; and 16.5 % of women have been the victims of sexual violence. Female adolescents perpetrate physical violence more frequently than males, while perpetration between genders of other types of violence is unclear. Furthermore, poor, marginalized youth are at a higher risk for experiencing dating violence...
October 14, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
Kim Ashburn, Brad Kerner, Dickens Ojamuge, Rebecka Lundgren
Violence against women and violence against children in Uganda are recognized as significant public health concerns. Exposure to violence at home as a child can increase the likelihood of perpetrating or experiencing violence later in life. These two forms of violence share similar risk factors and often, but not always, co-occur at the household level. Parenting programs have shown promise in reducing physical child punishment. Targeting men has also been proven effective in transforming attitudes related to gender roles and expectations and intimate partner violence (IPV) against women...
October 13, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
Aditya Stanam, Katherine N Gibson-Corley, Laurie Love-Homan, Nnamdi Ihejirika, Andrean L Simons
Erlotinib has demonstrated poor clinical response rates for head and neck squamous cell carcinoma (HNSCC) to date and the majority of respondents acquire resistance to erlotinib relatively quickly. To elucidate novel pathways involved in erlotinib resistance, we compared the gene expression profiles of erlotinib-resistant (ER) vs. erlotinib-sensitive (ES) HNSCC cell lines. Enrichment analysis of microarray data revealed a deregulation of the IL-1 signaling pathway in ER versus ES-HNSCC cells. Gene expression of interleukin-1 alpha (IL1A) and interleukin-1 beta (IL1B) were significantly upregulated by > 2 fold in ER-SQ20B and ER-CAL 27 cells compared to their respective ES-cells...
October 12, 2016: Oncotarget
Silvia Orsulic-Jeras, Carol J Whitlatch, Sarah M Szabo, Evan G Shelton, Justin Johnson
This article describes the implementation of SHARE (Support, Health, Activities, Resources, and Education), a counseling-based care-planning intervention for persons living with early-stage dementia and their family caregivers (CGs). The foundation of SHARE is built upon assessing and documenting the person living with dementia's care values and preferences for future care. Using the SHARE approach, CGs are given an opportunity to achieve an understanding of their loved one's desires before the onset of disease progression when the demand for making care decisions is high...
October 13, 2016: Dementia
Tin Nguyen, Weiling Chiu, Xinying Wang, Madeleine O Sattler, Jennifer A Love
A mild protocol for Ni-catalyzed trifluoromethylthiolation of aryl chlorides and bromides is described herein. The method utilizes AgSCF3 as an easily accessible nucleophilic trifluoromethylthiolating reagent and does not require any ligands or additives. Ortho-selectivity is achieved using a variety of directing groups such as imines, pyridines, and oxazolines for 24 examples in up to 95% yield.
October 13, 2016: Organic Letters
Anne E Nigra, Keeve E Nachman, David C Love, Maria Grau-Perez, Ana Navas-Acien
BACKGROUND: Arsenicals (roxarsone and nitarsone) used in poultry production likely increase inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and roxarsone or nitarsone concentrations in poultry meat. The association between poultry intake and exposure to these arsenic species, as reflected in elevated urinary arsenic concentrations, however, is unknown. OBJECTIVES: Evaluate the association between 24-hour dietary recall of poultry consumption and arsenic exposure in the U...
October 13, 2016: Environmental Health Perspectives
Keeve E Nachman, David C Love, Patrick A Baron, Anne E Nigra, Manuela Murko, Georg Raber, Kevin A Francesconi, Ana Navas-Acien
BACKGROUND: Use of nitarsone, an arsenic-based poultry drug, may result in dietary exposures to inorganic arsenic (iAs) and other arsenic species. Nitarsone was withdrawn from the US market in 2015, but use in other countries may continue. OBJECTIVES: Characterize the impact of nitarsone use on arsenic species in turkey meat and arsenic exposures among turkey consumers, and estimate cancer risk increases from consuming turkey treated with nitarsone prior to its 2015 US withdrawal...
October 13, 2016: Environmental Health Perspectives
Abhishek Singh, Abhishek Nagpal, Salil Pawah, Chetan Pathak, Gaurav Issar, Pankaj Sharma
INTRODUCTION: In an attempt to minimize wear damage to the enamel of antagonist teeth, new low and medium fusing ceramic materials have been developed. Manufacturers usually claim that these ceramics are wear-friendly because of their lower hardness, lower concentrations of crystal phase, and smaller crystal sizes. This study aimed to quantitatively analyze the wear strength of various commercially available dental porcelain with tooth enamel as well as the surface hardness of these dental porcelain...
September 1, 2016: Journal of Contemporary Dental Practice
J Michael Bailey, Paula A Bernhard, Kevin J Hsu
We conducted an Internet survey of 1,102 men sexually attracted to children concerning their history of adjudicated offenses related to child pornography and sexual contact with children. Most of the men reported no offenses, but their rate of offenses was much higher than that expected for adult-attracted men. Correlates of offending are consistent with a strong role of the cumulative effects of temptation, especially age. Older men, men who had repeatedly worked in jobs with children, men who had repeatedly fallen in love with children, and men who had often struggled not to offend were especially likely to have offended...
October 2016: Journal of Abnormal Psychology
Nienke Nakken, Daisy J A Janssen, Esther H A van den Bogaart, Monique van Vliet, Geeuwke J de Vries, Gerben P Bootsma, Michiel H M Gronenschild, Jeannet M L Delbressine, Jean W M Muris, Emiel F M Wouters, Martijn A Spruit
BACKGROUND AND OBJECTIVE: Loved ones (proxies) of patients with COPD are confronted with the patients' limitations in activities of daily living (ADLs). However, it remains unknown whether proxies are able to correctly estimate the problematic ADLs of the patient. Therefore, we aimed to investigate the level of agreement between patient-reported and proxy-reported problematic ADLs of the patient. METHODS: Stable outpatients with moderate to very severe COPD (n = 194) and their resident proxies (n = 194) were included in this cross-sectional study...
October 12, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
Latisha Love-Gregory, Aldi T Kraja, Fiona Allum, Stella Aslibekyan, Åsa K Hedman, Yanan Duan, Ingrid B Borecki, Donna K Arnett, Mark I McCarthy, Panos Deloukas, Jose M Ordovas, Paul N Hopkins, Elin Grundberg, Nada A Abumrad
CD36 variants influence fasting lipids and risk of metabolic syndrome, but their impact on postprandial lipids, an independent risk factor for cardiovascular disease, is unclear. We determined effects of SNPs within a ~410-kb region encompassing CD36 and its proximal and distal promoters on chylomicron remnants (CM) and LDL particles at fasting, 3.5 and 6 hours following a high-fat meal (GOLDN study, n=1117). Five promoter variants associated with CM, four with delayed triglyceride clearance and five with LDL particle number...
October 11, 2016: Journal of Lipid Research
Christina Eguizabal Love, Frank Webbe, Gunha Kim, Ki Hyeong Lee, Michael Westerveld, Christine M Salinas
OBJECTIVE: Children with epilepsy are vulnerable to executive dysfunction, but the relationship between executive functioning (EF) and quality of life (QOL) in children with epilepsy is not fully delineated. This exploratory study elucidated the relationship between ecological EF and QOL in pediatric intractable epilepsy. METHOD: Fifty-four consecutively referred pediatric epilepsy surgery candidates and their parents were administered IQ measures, the Behavior Rating Inventory of Executive Function (BRIEF), and the Quality of Life in Childhood Epilepsy (QOLCE) as part of a comprehensive neuropsychological evaluation...
October 8, 2016: Epilepsy & Behavior: E&B
Andrew J Love, Chulang Yu, Natalia V Petukhova, Natalia O Kalinina, Jianping Chen, Michael E Taliansky
Cajal bodies (CBs) are distinct sub-nuclear structures that are present in eukaryotic living cells and are often associated with the nucleolus. CBs play important roles in RNA metabolism and formation of RNPs involved in transcription, splicing, ribosome biogenesis, and telomere maintenance. Besides these primary roles, CBs appear to be involved in additional functions that may not be directly related to RNA metabolism and RNP biogenesis. In this review, we assess possible roles of plant CBs in RNA regulatory pathways such as nonsense-mediated mRNA decay and RNA silencing...
October 11, 2016: RNA Biology
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