keyword
MENU ▼
Read by QxMD icon Read
search

Core

keyword
https://www.readbyqxmd.com/read/28922793/diurnal-cycling-transcription-factors-of-pineapple-revealed-by-genome-wide-annotation-and-global-transcriptomic-analysis
#1
Anupma Sharma, Ching Man Wai, Ray Ming, Qingyi Yu
Circadian clock provides fitness advantage by coordinating internal metabolic and physiological processes to external cyclic environments. Core clock components exhibit daily rhythmic changes in gene expression, and the majority of them are transcription factors (TFs) and transcription coregulators (TCs). We annotated 1,398 TFs from 67 TF families and 80 TCs from 20 TC families in pineapple, and analyzed their tissue-specific and diurnal expression patterns. Approximately 42% of TFs and 45% of TCs displayed diel rhythmic expression, including 177 TF/TCs cycling only in the nonphotosynthetic leaf tissue, 247 cycling only in the photosynthetic leaf tissue, and 201 cycling in both...
September 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28922763/chicory-r2r3-myb-transcription-factors-cimyb5-and-cimyb3-regulate-fructan-1-exohydrolase-expression-in-response-to-abiotic-stress-and-hormonal-cues
#2
Hongbin Wei, Hongbo Zhao, Tao Su, Anja Bausewein, Steffen Greiner, Karsten Harms, Thomas Rausch
In the biennial Cichorium intybus, inulin-type fructans accumulate in the taproot during the first year. Upon cold or drought exposure, fructans are degraded by fructan exohydrolases, affecting inulin yield and degree of polymerization. While stress-induced expression of 1-FEH genes has been thoroughly explored, the transcriptional network mediating these responses has remained unknown. In this study, several R2R3-MYB transcriptional regulators were analysed for their possible involvement in 1-FEH regulation via transient transactivation of 1-FEH target promoters and for in vivo co-expression with target genes under different stress and hormone treatments...
July 10, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28922606/three-dimensional-nico2o4-mnmoo4-core-shell-nanoarrays-for-high-performance-asymmetric-supercapacitors
#3
Yuliang Yuan, Weicheng Wang, Jie Yang, Haichao Tang, Zhizhen Ye, Yujia Zeng, Jianguo Lu
Design of new materials with sophisticated nanostructure has been proven to be an efficient strategy to improve their properties in many applications. Herein, we demonstrate the successful combination of high electron conductive materials of NiCo2O4 with the high capacitance materials of MnMoO4 by forming a core-shell nanostructure. The NiCo2O4@MnMoO4 core-shell nanoarrays (CSNAs) electrode possesses high specific capacitance of 4.24 F cm-2 at a current density of 5 mA cm-2, obviously larger than the pristine NiCo2O4 electrode...
September 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28922603/semiconductor-plasmon-induced-upconversion-enhancement-in-mcu2-xs-sio2-y2o3-yb-3-er-3-core-shell-nanocomposites
#4
Donglei Zhou, Dongyu Li, Xiangyu Zhou, Wen Xu, Xu Chen, Dali Liu, Yongsheng Zhu, Hongwei Song
The ability to modulate the intensity of electromagnetic field by semiconductor plasmon nanoparticles is becoming attractive owing to its unique doping induced local surface plasmon resonance (LSPR) effect different from metals. Herein, we synthesized the mCu2-xS@SiO2@Y2O3:Yb(3+),Er(3+) core-shell composites and experimentally and theoretically studied the semiconductor plasmon induced upconversion (UC) enhancement, and obtained 30 folds UC enhancement compared to that of SiO2@Y2O3:Yb(3+),Er(3+) composites...
September 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28922597/core-shell-silver-nanoparticles-in-endodontic-disinfection-solutions-enable-long-term-antimicrobial-effect-on-oral-biofilms
#5
Elif Ertem Bekdemir, Beatrice Gutt, Flavia Zuber, Sergio Allegri, Benjamin Le Ouay, Selma Mefti, Kitty Formentin, Francesco Stellacci, Qun Ren
To achieve effective long-term disinfection of the root canals, we synthesized core-shell silver nanoparticles (AgNPs@SiO2) and used them to develop two irrigation solutions containing sodium phytate (SP) and ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA), respectively. Ex vivo studies with instrumented root canals revealed that the developed irrigation solutions can effectively remove the smear layer from the dentinal surfaces. Further in vitro experiments with single and multi-species biofilms demonstrated for the first time that AgNPs@SiO2 based irrigation solutions possess excellent antimicrobial activities for at least 7 days, whereas the bare AgNPs lose the activity almost immediately and do not show any antibacterial activity after 2 days...
September 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28922501/formation-and-structural-diversity-of-organo-functionalized-tin-silver-selenide-clusters
#6
Stefanie Dehnen, Niklas Rinn, Lukas Guggolz, Katharina Gries, Kerstin Volz, Jürgen Senker
When reacting the organic functionalized tin selenide clusters [(SnR1)3Se4Cl] (A, R1 = CMe2CH2C(O)Me) or [(SnR1)4Se6] (B) with (SiMe3)2Se and [Ag(PPh3)3Cl] at -78°C in CH2Cl2, a microcrystalline, intermediate (compound 1) precipitates, which was investigated by magic angle spinning (MAS) NMR spectroscopy, powder X-ray diffraction (PXRD), energy dispersive X-ray (EDX) spectroscopy, and quantum chemistry. From these studies, a suggestion about its identity was derived. Compound 1 re-dissolves under reorganization into the organo-functionalized Ag/Sn/Se cluster compound [Ag6(μ6 Se)(Ag8Se12){(R1Sn)2Se2}6] (2), or the mixed-valence cluster [(AgPPh3)2(SnIICl)2Se2{(R1SnIV)2Se2}2] (3), depending on the presence or the exclusion of daylight, respectively...
September 18, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28922373/dynein-light-chain-regulates-adaptive-and-innate-b-cell-development-by-distinctive-genetic-mechanisms
#7
Ashleigh King, Lingli Li, David M Wong, Rui Liu, Rebecca Bamford, Andreas Strasser, David M Tarlinton, Jörg Heierhorst
Mechanistic differences in the development and function of adaptive, high-affinity antibody-producing B-2 cells and innate-like, "natural" antibody-producing B-1a cells remain poorly understood. Here we show that the multi-functional dynein light chain (DYNLL1/LC8) plays important roles in the establishment of B-1a cells in the peritoneal cavity and in the ongoing development of B-2 lymphoid cells in the bone marrow of mice. Epistasis analyses indicate that Dynll1 regulates B-1a and early B-2 cell development in a single, linear pathway with its direct transcriptional activator ASCIZ (ATMIN/ZNF822), and that the two genes also have complementary functions during late B-2 cell development...
September 18, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28922294/health-professionals-quality-of-life-in-relation-to-end-of-life-care
#8
Juan P Linzitto, Gladys Grance
PURPOSE OF REVIEW: Palliative care professionals are frequently exposed to stressful and demanding situations in the assistance of patients and their families, therefore research related to their quality of life is a relevant topic to provide evidence on interventions oriented to professional self-care. RECENT FINDINGS: Research about professionals' quality of life is having a profuse development with core concepts being under review. SUMMARY: Currently, burnout syndrome and compassion fatigue are considered relevant determinants of professionals' quality of life...
September 15, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/28922236/efficacy-outcome-measures-for-pediatric-procedural-sedation-clinical-trials-an-acttion-systematic-review
#9
Mark R Williams, Michael Nayshtut, Amie Hoefnagel, Andrew McKeown, Douglas W Carlson, Joseph Cravero, Jenifer Lightdale, Keira P Mason, Stephen Wilson, Dennis C Turk, Robert H Dworkin, Denham S Ward
Objective evaluations comparing different techniques and approaches to pediatric procedural sedation studies have been limited by a lack of consistency among the outcome measures used in assessment. This study reviewed those existing measures, which have undergone psychometric analysis in a pediatric procedural sedation setting, to determine to what extent and in what circumstances their use is justified across the spectrum of procedures, age groups, and techniques. The results of our study suggest that a wide range of measures has been used to assess the efficacy and effectiveness of pediatric procedural sedation...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28922123/a-data-driven-approach-for-furniture-and-indoor-scene-colorization
#10
Jie Zhu, Yanwen Guo, Han Ma
We present a data-driven approach that colorizes 3D furniture models and indoor scenes by leveraging indoor images on the internet. Our approach is able to colorize the furniture automatically according to an example image. The core is to learn image-guided mesh segmentation to segment the model into different parts according to the imaged object. Given an indoor scene, the system supports colorization-by-example, and has the ability to recommend the colorization scheme that is consistent with a user-desired color theme...
September 18, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28921989/universal-calibration-of-computationally-predicted-n-1s-binding-energies-for-interpretation-of-xps-experimental-measurements
#11
Jing Zhao, Fei Gao, Sidharam Pundlik Pujari, Han Zuilhof, Andrew Teplyakov
Computationally predicted N 1s core level energies are commonly used to interpret the experimental measurements obtained with X-ray photoelectron spectroscopy. This work compares the application of Koopmans' theorem to core electrons using the B3LYP functional with two commonly used basis sets, analyses the factors relevant to the comparison of the computational with experimental data, and presents several correlations that allow an accurate prediction of the N 1s binding energy. The first correlation is obtained with a series of known nitrogen-containing functional groups on well-characterized organic monolayers...
September 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28921970/tris-heteroleptic-iridium-complexes-based-on-cyclometalated-ligands-with-different-cores
#12
Yanouk Cudré, Felipe Franco de Carvalho, Gregory R Burgess, Louise Male, Simon J A Pope, Ivano Tavernelli, Etienne Baranoff
A series of tris-heteroleptic iridium complexes of the form [Ir(C^N(1))(C^N(2))(acac)] combining 2-phenylpyridine (ppy), 2-(2,4-difluorophenyl)pyridine (dFppy), 1-phenylpyrazole (ppz), and 1-(2,4-difluorophenyl)pyrazole (dFppz) as the C^N ligands have been synthesized and fully characterized by NMR, X-ray crystallography, UV-vis absorption and emission spectroscopy, and electrochemical methods. It is shown that "static properties" (e.g., absorption and emission spectra and redox potentials) are primarily dictated by the overall architecture of the complex, while "dynamic properties" (e...
September 18, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28921964/versatile-synthetic-route-for-%C3%AE-functionalized-chlorins-and-porphyrins-by-varying-the-size-of-michael-donors-syntheses-photophysical-and-electrochemical-redox-properties
#13
Nivedita Chaudhri, Nitika Grover, Muniappan Sankar
One-pot facile synthesis and characterization of novel β-substituted meso-tetraphenylporphyrins and/or chlorins were described. The high regioselective reactivity of active methylene compounds in Michael addition reaction was reported to access β-substituted trans-chlorins. Size-dependent approach was applied for the fine-tuning of product formation from porphyrins to chlorins. Notably, we were able to isolate mono/trisubstituted porphyrin and/or di/tetra-substituted chlorin from one-pot synthesis for the first time in porphyrin chemistry...
September 18, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28921929/tumor-suppressive-mir-145-co-repressed-by-tcf4-%C3%AE-catenin-and-prc2-complexes-forms-double-negative-regulation-loops-with-its-negative-regulators-in-colorectal-cancer
#14
Wei Wang, Xin Xiao, Xu Chen, Yi Huo, Wen-Jin Xi, Zhi-Feng Lin, Dan Zhang, Yu-Fang Li, Fan Yang, Wei-Hong Wen, An-Gang Yang, Tao Wang
The frequently dysregulated Wnt/β-catenin signaling in different malignancies, by activation of its own or orchestration with other co-factors, regulates various oncogenic or tumor-suppressive genes. Among these genes, miRNAs, which are negative posttranscriptional regulators, are also embedded in the Wnt signaling network. Different from the Wnt-induced oncogenic miRNAs, the specific mechanism underlying the Wnt-repressed tumor-suppressive miRNAs is much less understood. In the present study, firstly by analyzing a ChIP-seq dataset against TCF4, the core transcription factor for initiation of Wnt signaling in colorectal cancer (CRC) cells, we screened out several tumor-suppressive miRNAs potentially regulated by Wnt signaling...
September 16, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28921914/comparison-of-relation-between-multiple-parameters-of-glycemic-variability-and-coronary-plaque-vulnerability-assessed-by-virtual-histology-intravascular-ultrasound
#15
Natsu Otowa-Suematsu, Kazuhiko Sakaguchi, Hisako Komada, Tomoaki Nakamura, Anna Sou, Yushi Hirota, Masaru Kuroda, Toshiro Shinke, Ken-Ich Hirata, Wataru Ogawa
AIMS/INTRODUCTION: Increased glycemic variability is an important contributing factor to coronary artery disease. Although various parameters of glycemic variability can be derived by continuous glucose monitoring, the clinical relevance of individual parameters has remained unclear. We have now analyzed the relation of such parameters to coronary plaque vulnerability MATERIALS AND METHODS: The standard deviation of glucose levels (SD glucose), mean amplitude of glycemic excursions (MAGE), continuous overlapping net glycemic action calculated every 1 h (CONGA-1), and mean of daily differences (MODD) were calculated from continuous glucose monitoring data for 53 subjects hospitalized for percutaneous coronary intervention...
September 16, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28921886/clinical-practices-and-attitudes-regarding-the-diagnosis-and-management-of-heart-failure-findings-from-the-core-needs-assessment-survey
#16
Jonathan Howlett, Josep Comin-Colet, Kenneth Dickstein, Ahmet Fuat, Gerhard Pölzl, Sean Delaney
AIMS: CORE is a continuing medical education initiative designed to support the evidence-based management of heart failure (HF) in the primary and secondary care settings. The goal of the CORE Needs Assessment Survey is to describe current clinical practice patterns and attitudes among global stakeholders in HF care. METHODS AND RESULTS: The CORE Steering Committee guided the development of survey questions to assess clinical practice, confidence, and attitudes/perceptions among cardiologists, primary care physicians, and nurses involved in HF management...
September 18, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28921850/prospective-comparison-of-transperineal-mri-ultrasound-fusion-biopsy-and-transrectal-systematic-biopsy-in-biopsy-na%C3%A3-ve-patients
#17
Angelika Borkowetz, Boris Hadaschik, Ivan Platzek, Marieta Toma, Georgi Torsev, Theresa Renner, Roman Herout, Martin Baunacke, Michael Laniado, Gustavo Baretton, Jan Philipp Radtke, Claudia Kesch, Markus Hohenfellner, Michael Froehner, Heinz-Peter Schlemmer, Manfred Wirth, Stefan Zastrow
OBJECTIVES: To evaluate the value of multiparametric magnetic resonance imaging (mpMRI) for the detection of significant prostate cancer (PCa) and to compare transperineal MRI/ultrasound-fusion biopsy (fusPbx) to conventional transrectal systematic biopsy (sysPbx) in biopsy-naïve patients. PATIENTS AND METHODS: This multicentre, prospective trial investigated biopsy-naïve patients with suspicion of PCa undergoing transperineal fusPbx in combination with transrectal sysPbx (comPbx)...
September 16, 2017: BJU International
https://www.readbyqxmd.com/read/28921821/iridium-catalyzed-direct-c-h-amidation-polymerization-step-growth-polymerization-by-c-n-bond-formation-via-c-h-activation-to-give-fluorescent-polysulfonamides
#18
Tae-Lim Choi, Jang Yoon-Jung, Soon-Hyeok Hwang
We report a powerful strategy for activation of C-H bonds to produce polysulfonamides by an atom-economical and green method using iridium-catalyzed direct C-H amidation polymerization (DCAP). After screening various directing groups, additives, silver salts, concentrations, and temperatures to optimize DCAP, high molecular-weight (up to 149 kDa) and defect-free polysulfonamides were synthesized from various bis-sulfonyl azides. Although these polymers do not have conventional fluorescent conjugated cores, they emit blue light with large Stokes shifts and high quantum yields upon photoexcitation, due to excited-state intramolecular proton transfer process...
September 15, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28921785/cancer-specific-mortality-of-high-risk-prostate-cancer-after-carbon-ion-radiotherapy-plus-long-term-androgen-deprivation-therapy
#19
Goro Kasuya, Hitoshi Ishikawa, Hiroshi Tsuji, Yasuo Haruyama, Gen Kobashi, Daniel K Ebner, Koichiro Akakura, Hiroyoshi Suzuki, Tomohiko Ichikawa, Jun Shimazaki, Hirokazu Makishima, Takuma Nomiya, Tadashi Kamada, Hirohiko Tsujii
The treatment outcomes of patients with high-risk localized prostate cancer (PC) after carbon-ion radiotherapy (CIRT) combined with long-term androgen deprivation therapy (LTADT) were analyzed, and compared with those of other treatment modalities, focusing on PC-specific mortality (PCSM). A total of 1247 patients were enrolled in three phase II clinical trials of fixed-dose CIRT between 2000 and 2013. Excluding patients with T4 disease, 608 patients with high- or very-high-risk PC, according to the National Comprehensive Cancer Network classification system, who received CIRT with LTADT were evaluated...
September 16, 2017: Cancer Science
https://www.readbyqxmd.com/read/28921711/foxp-expression-identifies-a-kenyon-cell-subtype-in-the-honeybee-mushroom-bodies-linking-them-to-fruitfly-%C3%AE-%C3%AE-c-neurons
#20
Adriana Schatton, Constance Scharff
The arthropod mushroom bodies (MB) are a higher order sensory integration center. In insects, they play a central role in associative olfactory learning and memory. In Drosophila melanogaster (Dm), the highly ordered connectivity of heterogeneous MB neuron populations has been mapped using sophisticated molecular genetic and anatomical techniques. The MB-core subpopulation was recently shown to express the transcription factor FoxP with relevance for decision-making. Here we report the development and adult distribution of a FoxP-expressing neuron population in the MB of honeybees (Apis mellifera, Am) using in situ hybridization and a custom-made antiserum...
September 16, 2017: European Journal of Neuroscience
keyword
keyword
45999
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"