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Olivia A Attallah, W K B Khalil, Mohamed M S Abdel Mottaleb, E Girgis
In our present work some biological tests were carried out to assess the biocompatibility of nicotinic acid coated magnetite nanorods. Pure and coated nanorods were injected intraperitoneally to cholesterol fed mice with dose values of 25, 50 mg/Kg. Investigations were done on treated mice with/without exposure to low frequency electromagnetic field (EMF) and samples were collected fourteen days post treatment. Toxicological effects were evaluated using Micronucleus and DNA fragmentation analysis. The results indicated that low dose (25 mg/Kg) nicotinic acid coated nanorods had insignificant toxicological effects in comparison to that of control group...
February 1, 2018: Journal of Nanoscience and Nanotechnology
Hamideh Mahmoudinasab, Mostafa Saadat
Cisplatin [cis-dichlorodiammine platinum (II), CDDP], morphine (Mor), and electromagnetic field (EMF) induced oxidative stress. In this study, we tried to increase the cytotoxicity of CDDP in combination with Mor and/or EMF in MCF-7 and SH-SY5Y cells. Furthermore, we evaluate the expression levels of 11 antioxidant genes in both cell lines. We designed four treatments: CDDP alone, "CDDP+Mor," "CDDP+EMF," and "CDDP+Mor+EMF." Serial dilutions of CDDP, Mor (5.0 μM), and EMF (50 Hz, 0...
February 15, 2018: DNA and Cell Biology
Marije Reedijk, Virissa Lenters, Pauline Slottje, Anouk Pijpe, Petra H Peeters, Joke C Korevaar, Bas Bueno-de-Mesquita, W M Monique Verschuren, Robert A Verheij, Inka Pieterson, Flora E van Leeuwen, Matti A Rookus, Hans Kromhout, Roel C H Vermeulen
PURPOSE: LIFEWORK is a large federated prospective cohort established in the Netherlands to quantify the health effects of occupational and environmental exposures. This cohort is also the Dutch contribution to the international Cohort Study of Mobile Phone Use and Health (COSMOS). In this paper, we describe the study design, ongoing data collection, baseline characteristics of participants and the repeatability of key questionnaire items. PARTICIPANTS: 88 466 participants were enrolled in three cohort studies in 2011-2012...
February 3, 2018: BMJ Open
J Q Lan, X Liang, T Hong, G H Du
This paper evaluates the effects of glasses on the specific absorption rates (SAR) in the human head resulting from wireless eyewear device at phone call state. We mainly concentrate on the SAR in the eyes since their sensitivity to electromagnetic fields (EMF). We find wearing glasses obviously alters the distribution and magnitude of the SAR. The maximal SAR in the ocular tissues with glasses is even 6 times more than that without glasses. Wearing glasses also induce the new hotspot in the eyes which may cause the biggest SAR increment in the ocular tissues...
February 8, 2018: Progress in Biophysics and Molecular Biology
Adem Kocaman, Gamze Altun, Arife Ahsen Kaplan, Ömür Gülsüm Deniz, Kıymet Kübra Yurt, Süleyman Kaplan
New technologies in electronics and communications are continually emerging. An increasing use of these electronic devices such as mobile phone, computer, wireless fidelity connectors or cellular towers is raising questions concerning whether they have an adverse effect on the body. Exposure to electromagnetic fields (EMF) is frequently suggested to have adverse health effects on humans and other organisms. This idea has been reported in many studies. In contrast, the therapeutic effects of EMF on different organs have also been reported...
February 7, 2018: Environmental Research
Luigi F Agnati, Manuela Marcoli, Guido Maura, Amina Woods, Diego Guidolin
Investigations of brain complex integrative actions should consider beside neural networks, glial, extracellular molecular, and fluid channels networks. The present paper proposes that all these networks are assembled into the brain hyper-network that has as fundamental components, the tetra-partite synapses, formed by neural, glial, and extracellular molecular networks. Furthermore, peri-synaptic astrocytic processes by modulating the perviousness of extracellular fluid channels control the signals impinging on the tetra-partite synapses...
February 9, 2018: Journal of Neural Transmission
Nasibeh Roozbeh, Fatemeh Abdi, Azadeh Amraee, Zahra Atarodi Kashani, Leili Darvish
BACKGROUND: Due to the increased number of users of mobile phones, tablets, and other devices over the past few years, concerns about the potential impact of mobile phones on health are growing. The influence of mobile phone exposure on male fertility has been studied in recent years. Other research has shown that electromagnetic fields (EMFs) increase macrophages in the corpus luteum and growing follicles. Due to conflicting results among studies and since no systematic review has been performed to analyze the effects of radiofrequency EMF exposure from electronic devices on the fertility system in recent years, this evidence-based study is necessary...
February 8, 2018: JMIR Research Protocols
Serena Fiocchi, Emma Chiaramello, Marta Parazzini, Paolo Ravazzani
Human exposure to extremely low frequency magnetic fields (ELF-MF) at 50 Hz is still a topic of great interest due to the possible correlation with childhood leukaemia. The estimation of induced electric fields in human tissues exposed to electromagnetic fields (EMFs) strictly depends on several variables which include the dielectric properties of the tissues. In this paper, the influence of the conductivity assignment to foetal tissues at different gestational ages on the estimation of the induced electric field due to ELF-MF exposure at 50 Hz has been quantified by means of a stochastic approach using polynomial chaos theory...
2018: PloS One
Hila Naaman, Tatiana Rabinski, Avi Yizhak, Solly Mizrahi, Yonat Shemer Avni, Ran Taube, Bracha Rager, Yacov Weinstein, Glenn Rall, Jacob Gopas, Rivka Ofir
In this study, we found that the measles virus (MV) can infect human-induced pluripotent stem cells (hiPSCs). Wild-type MV strains generally use human signaling lymphocyte activation molecule (SLAM; CD150) as a cellular receptor, while vaccine strains such as the Edmonston strain can use both CD150 and CD46 as receptors. It is not yet known how early in the embryonal differentiation stages these receptors are expressed. We established two hiPSCs (BGU-iPSCs and EMF-iPSCs) which express CD46 and CD150. Both cell types can be infected by MV to form persistent, noncytopathic cell lines that release infectious MV particles...
February 2018: Cellular Reprogramming
Agostino Di Ciaula
The spread of radiofrequency electromagnetic fields (RF-EMF) is rising and health effects are still under investigation. RF-EMF promote oxidative stress, a condition involved in cancer onset, in several acute and chronic diseases and in vascular homeostasis. Although some evidences are still controversial, the WHO IARC classified RF-EMF as "possible carcinogenic to humans", and more recent studies suggested reproductive, metabolic and neurologic effects of RF-EMF, which are also able to alter bacterial antibiotic resistance...
February 2, 2018: International Journal of Hygiene and Environmental Health
Saleh H Salmen, Sulaiman A Alharbi, Asmaa A Faden, M Wainwright
This study was aimed to evaluate the impact of high frequency electromagnetic fields (HF-EMF at 900 and 1800 MHz) on DNA, growth rate and antibiotic susceptibility of S. aureus, S. epidermidis, and P. aeruginosa. In this study, bacteria were exposed to 900 and 1800 MHz for 2 h and then inoculated to new medium when their growth rate and antibiotic susceptibility were evaluated. Results for the study of bacterial DNA unsuccessful to appearance any difference exposed and non-exposed S. aureus and S. epidermidis...
January 2018: Saudi Journal of Biological Sciences
Xingxing Zhang, Yaofeng Wang, Roser Morales-Martínez, Jun Zhong, Coen de Graaf, Antonio Rodríguez-Fortea, Josep M Poblet, Luis Echegoyen, Lai Feng, Ning Chen
The nature of actinide-actinide bonds has attracted considerable attention for a long time, especially since recent theoretical studies suggest that triple and up to quintuple bonds should be possible, but little is known experimentally. Actinide-actinide bonds inside fullerene cages have also been proposed, but their existence has been debated intensively by theoreticians. Despite all the theoretical arguments, critical experimental data for a dimetallic actinide endohedral fullerene have never been obtained...
January 27, 2018: Journal of the American Chemical Society
Liling Su, Aziguli Yimaer, Zhengping Xu, Guangdi Chen
PURPOSE: To systematically evaluate the effects of 1800 MHz radiofrequency electromagnetic fields (RF-EMF) exposure on DNA damage and cellular functions in primary cultured neurogenic cells. MATERIALS AND METHODS: The primary cultured astrocytes, microglia and cortical neurons were exposed to RF-EMF at a SAR of 4.0 W/kg. The DNA damage was evaluated by γH2AX foci formation assay. The secretion of pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) in astrocytes and microglia, microglial phagocytic activity and neuronal development were examined by enzyme-linked immunosorbent assay, phagocytosis assay and immunofluorescent staining on microtubule-associated protein tau, microtubule-associated protein 2, postsynaptic density 95 and gephyrin, respectively...
January 25, 2018: International Journal of Radiation Biology
Ana Luiza C Sayegh, Marcelo R Dos Santos, Patricia de Oliveira, Fábio Fernandes, Eduardo Rondon, Francis R de Souza, Vera M C Salemi, Maria Janieire de N N Alves, Charles Mady
BACKGROUND: Endomyocardial fibrosis (EMF) is a rare disease, characterized by diastolic dysfunction which leads to reduced peak oxygen consumption (VO2). Cardiopulmonary exercise testing (CPET) has been proved to be a fundamental tool to identify central and peripheral alterations. However, most studies prioritize peak VO2 as the main variable, leaving aside other important CPET variables that can specify the severity of the disease and guide the clinical treatment. OBJECTIVE: The aim of this study was to evaluate central and peripheral limitations in symptomatic patients with EMF by different CPET variables...
December 2017: Arquivos Brasileiros de Cardiologia
B Y Zhu, Z D Yang, X R Chen, J Zhou, Y H Gao, C J Xian, K M Chen
We proposed a three-step strategy to obtain the optimal therapeutic parameters, which is composed of large-scale screening at cellular level, verification in animal experiments, and confirmation by a clinical trial. The objective of the current study was to test the feasibility of our strategy. Newborn rat calvarial osteoblasts were treated by 50 Hz 1.8 mT sinusoidal electromagnetic fields (SEMFs) with 0.5, 1.0, 1.5, 2.0, 2.5, and 3.0 h/days, respectively. The osteogenic differentiation and maturation of the osteoblast were assayed and compared to obtain the optimal duration...
January 23, 2018: Calcified Tissue International
A Patruno, A Ferrone, E Costantini, S Franceschelli, M Pesce, L Speranza, P Amerio, C D'Angelo, M Felaco, A Grilli, M Reale
OBJECTIVES: In our previous reports, we have demonstrated that extremely low-frequency electromagnetic fields (ELF-EMF) exposure enhances the proliferation of keratinocyte. The present study aimed to clarify effects of ELF-EMF on wound healing and molecular mechanisms involved, using a scratch in vitro model. MATERIALS AND METHODS: The wounded monolayer cultures of human immortalized keratinocytes (HaCaT), at different ELF-EMF and Sham exposure times were monitored under an inverted microscope...
January 22, 2018: Cell Proliferation
Anna Koziorowska, Ewa Monika Waszkiewicz, Maria Romerowicz-Misielak, Kamila Zglejc-Waszak, Anita Franczak
An electromagnetic field (EMF) of extremely low frequency may affect physiological processes in mammals. The aim of the present study was to determine the effect of an EMF on the synthesis and secretion of oestradiol-17β (E2) in the porcine uterus. Endometrial and myometrial slices were harvested on days 12-13 of the oestrous cycle and exposed in vitro to an EMF (50 and 120 Hz, 8 mT) for 2 and 4 h in the presence or absence of progesterone (P4). Subsequently, the incubation media were used to determine the concentration of E2 with RIA...
January 9, 2018: Theriogenology
Antoine Delmas, Lamia Belguerras, Nicolas Weber, Freddy Odille, Cédric Pasquier, Jacques Felblinger, Pierre-André Vuissoz
A Magnetic Resonance Imaging (MRI) scanner uses three different electromagnetic fields (EMF) to produce body images: a static permanent magnetic field (MF), several pulsed magnetic gradients, and a radiofrequency pulse. As a result, any occupation that includes an MRI exposes workers to a strong MF. The World Health Organization has now given the monitoring of occupational EMF exposure a high priority. One design for a low-cost, compact MF exposure monitor (« MR exposimeter ») uses a set of three orthogonally assembled Hall sensors...
January 19, 2018: Bioelectromagnetics
Fatemeh Adibzadeh, Margarethus M Paulides, Gerard C van Rhoon
BACKGROUND AND PURPOSE: To protect against any potential adverse effects to human health from localised exposure to radio frequency (100 kHz-3 GHz) electromagnetic fields (RF EMF), international health organisations have defined basic restrictions on specific absorption rate (SAR) in tissues. These exposure restrictions incorporate safety factors which are generally conservative so that exposures that exceed the basic restrictions are not necessarily harmful. The magnitude of safety margin for various exposure scenarios is unknown...
January 18, 2018: International Journal of Hyperthermia
Valentina Hartwig, Stefania Romeo, Olga Zeni
The purpose of this review is to make a contribution to build a comprehensive knowledge of the main aspects related to the occupational exposure to electromagnetic fields (EMFs) in magnetic resonance imaging (MRI) environments. Information has been obtained from original research papers published in international peer-reviewed journals in the English language and from documents published by governmental bodies and authorities. An overview of the occupational exposure scenarios to static magnetic fields, motion-induced, time-varying magnetic fields, and gradient and radiofrequency fields is provided, together with a summary of the relevant regulation for limiting exposure...
January 18, 2018: Medical & Biological Engineering & Computing
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