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https://www.readbyqxmd.com/read/28434113/precision-knockdown-of-egfr-gene-expression-using-radio-frequency-electromagnetic-energy
#1
Ilya V Ulasov, Haidn Foster, Mike Butters, Jae-Geun Yoon, Tomoko Ozawa, Theodore Nicolaides, Xavier Figueroa, Parvinder Hothi, Michael Prados, John Butters, Charles Cobbs
Electromagnetic fields (EMF) in the radio frequency energy (RFE) range can affect cells at the molecular level. Here we report a technology that can record the specific RFE signal of a given molecule, in this case the siRNA of epidermal growth factor receptor (EGFR). We demonstrate that cells exposed to this EGFR siRNA RFE signal have a 30-70% reduction of EGFR mRNA expression and ~60% reduction in EGFR protein expression vs. control treated cells. Specificity for EGFR siRNA effect was confirmed via RNA microarray and antibody dot blot array...
April 22, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28430370/extremely-low-frequency-electromagnetic-field-elf-emf-reduces-oxidative-stress-and-improves-functional-and-psychological-status-in-ischemic-stroke-patients
#2
Natalia Cichoń, Michał Bijak, Elżbieta Miller, Joanna Saluk
As a result of ischaemia/reperfusion, massive generation of reactive oxygen species occurs, followed by decreased activity of antioxidant enzymes. Extremely low frequency electromagnetic fields (ELF-EMF) can modulate oxidative stress, but there are no clinical antioxidant studies in brain stroke patients. The aim of our study was to investigate the effect of ELF-EMF on clinical and antioxidant status in post-stroke patients. Fifty-seven patients were divided into two groups: ELF-EMF and non-ELF-EMF. Both groups underwent the same 4-week rehabilitation program...
April 21, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28426166/acute-effects-of-radiofrequency-electromagnetic-field-emitted-by-mobile-phone-on-brain-function
#3
REVIEW
Jun Zhang, Alexander Sumich, Grace Y Wang
Due to its attributes, characteristics, and technological resources, the mobile phone (MP) has become one of the most commonly used communication devices. Historically, ample evidence has ruled out the substantial short-term impact of radiofrequency electromagnetic field (RF-EMF) emitted by MP on human cognitive performance. However, more recent evidence suggests potential harmful effects associated with MP EMF exposure. The aim of this review is to readdress the question of whether the effect of MP EMF exposure on brain function should be reopened...
April 20, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28414399/current-understanding-of-the-health-effects-of-electromagnetic-fields
#4
Tayaba Miah, Deepak Kamat
There has been an exponential increase in the use of electronic devices over the past few decades. This has led to increased exposure to electromagnetic fields (EMF). Electric fields result from differences in voltage, whereas magnetic fields result from the flow of electric current. Higher-frequency waves of EMF have more energy than lower-frequency waves, and thus generally tend to be more harmful. An EMF activates cellular stress response and also causes breaks in DNA strands. There are many methodological barriers to effectively measuring the associations of EMF and childhood cancers...
April 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28401610/the-potential-for-mycobiont-sharing-between-shrubs-and-seedlings-to-facilitate-tree-establishment-after-wildfire-at-alaska-arctic-treeline
#5
Rebecca E Hewitt, F Stuart Chapin, Teresa N Hollingsworth, D Lee Taylor
Root-associated fungi, particularly ectomycorrhizal fungi (EMF), are critical symbionts of all boreal tree species. Although climatically-driven increases in wildfire frequency and extent have been hypothesized to increase vegetation transitions from tundra to boreal forest, fire reduces mycorrhizal inoculum. Therefore, changes in mycobiont inoculum may potentially limit tree-seedling establishment beyond current treeline. We investigated whether ectomycorrhizal shrubs that resprout after fire support similar fungal taxa to those that associate with tree seedlings that establish naturally after fire...
April 12, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28400751/ethanolic-extract-of-melia-fructus-has-anti-influenza-a-virus-activity-by-affecting-viral-entry-and-viral-rna-polymerase
#6
Young-Hee Jin, Jang-Gi Choi, Won-Kyung Cho, Jin Yeul Ma
Meliae Fructus (MF) is the dried ripe fruit of Melia toosendan Siebold et Zuccarini, Meliaceae family. MF is widely used in traditional medicine to treat inflammation and helminthic infection and has anti-bacterial, anti-oxidant, anti-cancer, anti-inflammatory, and analgesic activities. However, potential anti-influenza properties of MF have yet to be investigated. We determined whether an ethanolic extract of MF (EMF) has anti-viral activity via an EMF pre-, co-, and post-treatment assay, using the Influenza A/PR/8/34 and H3N2 virus on Madin-Darby canine kidney (MDCK) cells...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28398549/modeled-and-perceived-exposure-to-radio-frequency-electromagnetic-fields-from-mobile-phone-base-stations-and-the-development-of-symptoms-over-time-in-a-general-population-cohort
#7
Astrid L Martens, Pauline Slottje, Danielle R M Timmermans, Hans Kromhout, Marije Reedijk, Roel C H Vermeulen, Tjabe Smid
We assessed associations between modeled and perceived exposure to radio-frequency electromagnetic fields (RF-EMF) from mobile-phone base stations and the development of nonspecific symptoms and sleep disturbances over time. A population-based Dutch cohort study, the Occupational and Environmental Health Cohort Study (AMIGO) (n = 14,829; ages 31-65 years), was established in 2011/2012 (T0), with follow-up of a subgroup (n = 3,992 invited) in 2013 (T1; n = 2,228) and 2014 (T2; n = 1,740). We modeled far-field RF-EMF exposure from mobile-phone base stations at the home addresses of the participants using a 3-dimensional geospatial model (NISMap)...
April 7, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28397118/proteomic-analysis-of-continuous-900-mhz-radiofrequency-electromagnetic-field-exposure-in-testicular-tissue-a-rat-model-of-human-cell-phone-exposure
#8
Masood Sepehrimanesh, Nasrin Kazemipour, Mehdi Saeb, Saeed Nazifi, Devra Lee Davis
Although cell phones have been used worldwide, some adverse and toxic effects were reported for this communication technology apparatus. To analyze in vivo effects of exposure to radiofrequency-electromagnetic field (RF-EMF) on protein expression in rat testicular proteome, 20 Sprague-Dawley rats were exposed to 900 MHz RF-EMF for 0, 1, 2, or 4 h/day for 30 consecutive days. Protein content of rat testes was separated by high-resolution two-dimensional electrophoresis using immobilized pH gradient (pI 4-7, 7 cm) and 12% acrylamide and identified by MALDI-TOF/TOF-MS...
April 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28394434/case-control-study-on-occupational-exposure-to-extremely-low-frequency-electromagnetic-fields-and-glioma-risk
#9
Michael Carlberg, Tarmo Koppel, Mikko Ahonen, Lennart Hardell
BACKGROUND: Exposure to extremely low-frequency electromagnetic fields (ELF-EMF) was in 2002 classified as a possible human carcinogen, Group 2B, by the International Agency for Research on Cancer at WHO. METHODS: Life time occupations were assessed in case-control studies during 1997-2003 and 2007-2009. An ELF-EMF Job-Exposure Matrix was used for associating occupations with ELF exposure (μT). Cumulative exposure (μT-years), average exposure (μT), and maximum exposed job (μT) were calculated...
April 10, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28394175/early-morning-functional-impairments-in-stimulant-treated-children-with-attention-deficit-hyperactivity-disorder-versus-controls-impact-on-the-family
#10
Stephen V Faraone, Russell J Schachar, Russell A Barkley, Rick Nullmeier, F Randy Sallee
OBJECTIVE: Children with attention-deficit/hyperactivity disorder (ADHD) frequently manifest early morning functional (EMF) impairments before school. We conducted a quantitative research survey to assess the impact of these EMF impairments on the family unit (caregiver, spouse/partner, and siblings). STUDY DESIGN: We developed an online survey questionnaire to collect data from 300 primary caregivers of children with ADHD and 50 primary caregivers of children who did not have ADHD...
April 10, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28394116/improvement-of-soil-ecosystem-multifunctionality-by-dissipating-manure-induced-antibiotics-and-resistance-genes
#11
Yuting Liang, Meng Pei, Dandan Wang, Shengnan Cao, Xian Xiao, Bo Sun
The application of animal manure containing antibiotic residues to farmlands as an organic fertilizer causes a long-term potential threat to the ecological environment of farmland. This study analyzed the effects of abating typical antibiotics and resistance genes (ARGs) applied with pig manure on farmland soil as well as on soil ecosystem multifunctionality (EMF) and its influencing factor. The results showed that Lolium multiflorum exhibited significantly stronger abatement of typical antibiotics and ARGs when combined with biochar than when used alone (p < 0...
April 13, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28373666/effects-of-four-kinds-of-electromagnetic-fields-emf-with-different-frequency-spectrum-bands-on-ovariectomized-osteoporosis-in-mice
#12
Tao Lei, Feijiang Li, Zhuowen Liang, Chi Tang, Kangning Xie, Pan Wang, Xu Dong, Shuai Shan, Juan Liu, Qiaoling Xu, Erping Luo, Guanghao Shen
Electromagnetic fields (EMF) was considered as a non-invasive modality for treatment of osteoporosis while the effects were diverse with EMF parameters in time domain. In present study, we extended analysis of EMF characteristics from time domain to frequency domain, aiming to investigate effects of four kinds of EMF (LP (1-100 Hz), BP (100-3,000 Hz), HP (3,000-50,000 Hz) and AP (1-50,000 Hz)) on ovariectomized (OVX) osteoporosis (OP) in mice. Forty-eight 3-month-old female BALB/c mice were equally assigned to Sham, OVX, OVX + LP, OVX + BP, OVX + HP and OVX + AP groups (n = 8)...
April 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28371755/are-media-reports-able-to-cause-somatic-symptoms-attributed-to-wifi-radiation-an-experimental-test-of-the-negative-expectation-hypothesis
#13
Anne-Kathrin Bräscher, Koen Raymaekers, Omer Van den Bergh, Michael Witthöft
People suffering from idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) experience numerous non-specific symptoms that they attribute to EMF. The cause of this condition remains vague and evidence shows that psychological rather than bioelectromagnetic mechanisms are at work. We hypothesized a role of media reports in the etiology of IEI-EMF and investigated how somatosensory perception is affected. 65 healthy participants were instructed that EMF exposure can lead to enhanced somatosensory perception...
March 31, 2017: Environmental Research
https://www.readbyqxmd.com/read/28370033/extremely-low-frequency-electromagnetic-field-exposure-enhances-inflammatory-response-and-inhibits-effect-of-antioxidant-in-raw-264-7-cells
#14
Soo Jeong Kim, Ye Won Jang, Kyung Eun Hyung, Da Kyoung Lee, Kee Hyeob Hyun, Seung Hwarn Jeong, Kyung Hoon Min, Wonku Kang, Ji Hoon Jeong, So-Young Park, Kwang Woo Hwang
In recent years, there has been a dramatic increase in the number and variety of electronic devices that emit electromagnetic waves. Because people live and work in close proximity to these pieces of electrical equipment, there is growing concern surrounding the destruction of homeostasis by electromagnetic field exposure. In the present study, the effects of 60 Hz 0.8 mT extremely low-frequency electromagnetic fields (ELF-EMF) on a macrophage cell line (RAW 264.7) were examined. Under defined ELF-EMF exposure conditions, the production of nitric oxide and pro-inflammatory cytokines, TNF-α, IL-1β, and IL-6, were increased in RAW 264...
March 29, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28352903/rationalizing-the-relative-abundances-of-trimetallic-nitride-template-based-endohedral-metallofullerenes-from-aromaticity-measures
#15
M Garcia-Borràs, S Osuna, J M Luis, M Solà
The synthesis of endohedral metallofullerenes (EMFs) from a carbon soot sample of an arc discharge leads to a variety of EMFs that are obtained in different relative abundances. In the present work, we show that these abundances can be predicted from aromaticity calculations. In particular, we use the normalized Additive Local Aromaticity (ALAN) index. Our results show that the most abundant Sc3N-based and Y3N-based EMFs in fullerene soot are the most aromatic. This study reinforces the idea that aromaticity plays a key role in determining the stability of EMFs...
March 29, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28352117/berkson-error-adjustment-and-other-exposure-surrogates-in-occupational-case-control-studies-with-application-to-the-canadian-interocc-study
#16
Tamer Oraby, Siva Sivaganesan, Joseph D Bowman, Laurel Kincl, Lesley Richardson, Mary McBride, Jack Siemiatycki, Elisabeth Cardis, Daniel Krewski
Many epidemiological studies assessing the relationship between exposure and disease are carried out without data on individual exposures. When this barrier is encountered in occupational studies, the subject exposures are often evaluated with a job-exposure matrix (JEM), which consists of mean exposure for occupational categories measured on a comparable group of workers. One of the objectives of the seven-country case-control study of occupational exposure and brain cancer risk, INTEROCC, was to investigate the relationship of occupational exposure to electromagnetic fields (EMF) in different frequency ranges and brain cancer risk...
March 29, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28351768/context-sensitive-ecological-momentary-assessments-integrating-real-time-exposure-measurements-data-analytics-and-health-assessment-using-a-smartphone-application
#17
Luuk van Wel, Anke Huss, Philipp Bachmann, Marco Zahner, Hans Kromhout, Jürg Fröhlich, Roel Vermeulen
INTRODUCTION: Modern sensor technology makes it possible to collect vast amounts of environmental, behavioural and health data. These data are often linked to contextual information on for example exposure sources which is separately collected with considerable lag time, leading to complications in assessing transient and/or highly spatially variable environmental exposures. Context-Sensitive Ecological Momentary Assessments(1) (CS-EMAs) could be used to address this. We present a case study using radiofrequency-electromagnetic fields (RF-EMF) exposure as an example for implementing CS-EMA in environmental research...
June 2017: Environment International
https://www.readbyqxmd.com/read/28342187/effect-of-adverse-environmental-conditions-and-protective-clothing-on-temperature-rise-in-a-human-body-exposed-to-radiofrequency-electromagnetic-fields
#18
Stephen M Moore, Robert L McIntosh, Steve Iskra, Alireza Lajevardipour, Andrew W Wood
This study considers the computationally determined thermal profile of a finely discretized, heterogeneous human body model, simulating a radiofrequency electromagnetic field (RF-EMF) worker wearing protective clothing subject to RF-EMF exposure, and subject to various environmental conditions including high ambient temperature and high humidity, with full thermoregulatory mechanisms in place. How the human body responds in various scenarios was investigated, and the information was used to consider safety limits in current international RF-EMF safety guidelines and standards...
March 24, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28339498/enhancement-of-osteogenic-differentiation-of-rat-adipose-tissue-derived-mesenchymal-stem-cells-by-zinc-sulphate-under-electromagnetic-field-via-the-pka-erk1-2-and-wnt-%C3%AE-catenin-signaling-pathways
#19
Ezzatollah Fathi, Raheleh Farahzadi
Zinc ion as an essential trace element and electromagnetic fields (EMFs) has been reported to be involved in the regulation of bone metabolism. The aim of this study was to elucidate the effects of zinc sulphate (ZnSO4) on the osteogenic differentiation of adipose tissue-derived mesenchymal stem cells (ADSCs) in the presence of EMF as a strategy in osteoporosis therapy. Alkaline phophatase (ALP) activity measurement, calcium assay and expression of several osteoblastic marker genes were examined to assess the effect of ZnSO4 on the osteogenic differentiation of ADSCs under EMF...
2017: PloS One
https://www.readbyqxmd.com/read/28339132/formation-of-endohedral-metallofullerene-emf-ions-of-mnc2m-m%C3%A2-%C3%A2-la-y-n%C3%A2-%C3%A2-%C3%A2-6-50%C3%A2-%C3%A2-%C3%A2-2%C3%A2-m%C3%A2-%C3%A2-%C3%A2-194-in-the-laser-ablation-process-with-graphene-as-precursor
#20
Xianglei Kong, Xiaodi Bao
RATIONALE: Graphene has been found to be a versatile precursor for the generation of mono-endohedral metallofullerenes (EMFs) of alkali and alkali earth metal atoms. Thus, it is important to investigate whether graphene is also a good precursor for the generation of EMFs including multi-metal atoms or some transition metal atoms. METHODS: Experiments were performed on a 7.0 T Fourier transform ion cyclotron resonance (FT ICR) mass spectrometer. Laser ablation mass spectra were obtained by laser irradiation on mixtures of graphene and LaCl3 , YCl3 or HAuCl4 on a stainless steel plate...
March 24, 2017: Rapid Communications in Mass Spectrometry: RCM
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