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Ana Carolina P Souza, Roberto Zatz, Rodrigo B de Oliveira, Mirela A R Santinho, Marcia Ribalta, João E Romão, Rosilene M Elias
BACKGROUND: Urinary density (UD) has been routinely used for decades as a surrogate marker for urine osmolality (Uosm). We asked if UD can accurately estimate Uosm both in healthy subjects and in different clinical scenarios of kidney disease. METHODS: UD was assessed by refractometry. Uosm was measured by freezing point depression in spot urines obtained from healthy volunteers (N = 97) and in 319 inpatients with acute kidney injury (N = 95), primary glomerulophaties (N = 118) or chronic kidney disease (N = 106)...
2015: BMC Nephrology
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