keyword
MENU ▼
Read by QxMD icon Read
search

PRP platelet rich plasma

keyword
https://www.readbyqxmd.com/read/28943099/a-systematic-review-of-the-effects-of-platelet-rich-plasma-on-outcomes-for-patients-with-knee-osteoarthritis-and-following-total-knee-arthroplasty
#1
REVIEW
Tendai Aswad Muchedzi, Simon B Roberts
INTRODUCTION: Platelet rich plasma (PRP) has been suggested to be effective in the management of knee osteoarthritis. Review of current literature reveals conflicting evidence regarding the benefits of PRP in treating knee OA. Preclinical evidence supports the use of PRP injections to promote a favorable environment for joint tissue healing, targeting not only cartilage but also synovial and meniscal tissues which has a positive effect on delaying the progression of OA. Growth factors found in platelet granules are postulated to influence outcomes in knee OA and after total knee arthroplasty (TKA)...
September 21, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28922143/leukocyte-reduced-platelet-rich-plasma-stimulates-the-in-vitro-proliferation-of-adipose-tissue-derived-mesenchymal-stem-cells-depending-on-pdgf-signaling
#2
Siegmund Lang, Marietta Herrmann, Christian Pfeifer, Gero Brockhoff, Johannes Zellner, Michael Nerlich, Peter Angele, Lukas Prantl, Sebastian Gehmert, Markus Loibl
BACKGROUND: Platelet-rich Plasma (PRP) is suggested as xenoprotein-free cell-culture medium replacement for animal-derived supplements. OBJECTIVE: The aim of this study was to investigate PRP-triggered signaling in adipose derived mesenchymal stem cells (ASCs). METHODS: PRP was obtained from 4 male patients. We incubated ASCs in α-MEM with different Platelet derived growth factor (PDGF) subtypes or 10% or 20% pooled PRP or 20% fetal calf serum (FCS) prior to determination of the S-phase fraction (SPF)...
September 11, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28904970/responders-to-platelet-rich-plasma-in-osteoarthritis-a-technical-analysis
#3
REVIEW
Christophe Milants, Olivier Bruyère, Jean-François Kaux
PURPOSE: To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee osteoarthritis. MATERIALS AND METHODS: A comparison of the outcomes of randomized controlled trials (RCTs) included in the 3 most recent and high-quality meta-analyses to classify the different studies in 2 groups (bad responders group (BRG) and very good responders group (VGRG))...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28902937/inside-out-and-standard-vein-grafts-associated-with-platelet-rich-plasma-prp-in-sciatic-nerve-repair-a-histomorphometric-study
#4
José Sidney Roque, Karina Torres Pomini, Rogério Leone Buchaim, Daniela Vieira Buchaim, Jesus Carlos Andreo, Domingos Donizeti Roque, Antonio de Castro Rodrigues, Geraldo Marco Rosa, Luis Henrique Rapucci Moraes, Fausto Viterbo
Purpose: To evaluated the tubulization technique with standard and inside-out vein, filled or not with platelet-rich plasma (PRP), in sciatic nerve repair. Methods: Seventy male Wistar rats were randomly divided into five groups: IOVNF (Inside-Out Vein with No Filling); IOVPRP (Inside-Out Vein filled with PRP); SVNF (Standard Vein with No Filling); SVPRP (Standard Vein filled with PRP); Sham (Control). The left external jugular vein was used as graft in a 10 mm nervous gap...
August 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28900383/effects-of-platelet-rich-plasma-and-chondrocyte-co-culture-on-msc-chondrogenesis-hypertrophy-and-pathological-responses
#5
Rouhallah Ramezanifard, Mahboubeh Kabiri, Hana Hanaee Ahvaz
Regarding the inadequate healing capability of cartilage tissue, cell-based therapy is making the future of cartilage repair and regeneration. Mesenchymal stem cells (MSC) have shown great promise in cartilage regeneration. However, a yet-unresolved issue is the emergence of hypertrophic and pathologic markers during in vitro MSC chondrogenesis. Articular chondrocytes (AC) can suppress the undesired hypertrophy when co-cultured with MSC. On the other hand, platelet rich plasma (PRP), is considered potentially effective for cartilage repair and in-vitro chondrogenesis...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28895770/the-use-of-platelet-rich-plasma-prp-in-the-treatment-of-gastrocnemius-strains-a-retrospective-observational-study
#6
Paolo Borrione, Chiara Fossati, Maria Teresa Pereira, Silvana Giannini, Marco Davico, Carlo Minganti, Fabio Pigozzi
The aim of the present retrospective observational study was to evaluate the time of functional recovery following a specific combined therapeutic approach characterized by an active exercise therapy carried out immediately after Platelet-rich plasma (PRP) injections for the treatment of the muscular lesion of the distal musculotendinous junction of the gastrocnemius medial head.Medical records of 31 subjects treated with three PRP intra-lesional ultrasound guided injections and 30 patients treated with the standard therapeutic approach (control group) were analyzed...
September 12, 2017: Platelets
https://www.readbyqxmd.com/read/28887865/plasma-rich-plasma-the-ultimate-secret-for-youthful-skin-elixir-and-hair-growth-triggering
#7
REVIEW
Ebtisam Elghblawi
The clinical application of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors that are released from alpha-granule of the concentrated platelets and in the secretion of proteins which are able to capitalize on the healing process at the cellular level. It has been invented to restore the natural beauty by starting the natural rejuvenation process of the skin and aiming to make it function as a younger one and to keep the skin youthful and maintain it. Besides that, it is also emerged to include hairs as a new injectable procedure to enable stimulating hair growth locally and topically; preventing its fall; improving hair shaft, hair stem, and its caliber; increasing its shine, vitality, and pliability; and declining hair splitting and breakage...
September 8, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28886194/a-new-rabbit-model-of-impaired-wound-healing-in-an-x-ray-irradiated-field
#8
Kazutoshi Fujita, Soh Nishimoto, Toshihiro Fujiwara, Yohei Sotsuka, Maki Tonooka, Kenichiro Kawai, Masao Kakibuchi
Radiation is an important therapy for cancer with many benefits; however, its side effects, such as impaired wound healing, are a major problem. While many attempts have been made to overcome this particular disadvantage, there are few effective treatments for impaired wound healing in an X-ray-irradiated field. One reason for this deficiency is the lack of experimental models, especially animal models. We have previously reported a mouse model of impaired wound healing in which the irradiation area was restricted to the hindlimbs...
2017: PloS One
https://www.readbyqxmd.com/read/28881440/injectable-mussel-inspired-immobilization-of-platelet-rich-plasma-on-microspheres-bridging-adipose-micro-tissues-to-improve-autologous-fat-transplantation-by-controlling-release-of-pdgf-and-vegf-angiogenesis-stem-cell-migration
#9
Shaolong Zhou, Qiang Chang, Feng Lu, Malcolm Xing
Platelets-rich plasma (PRP) can produce growth factors (GFs) to improve angiogenesis. However, direct injection of PRP does not lead to highly localized GFs. The current study employs a mussel-inspired polydopamine to immobilize PRP on gelatin microspheres (GMs) with the purpose of bridging adipose micro-tissues to help implanted fat survive (GM-pDA-PRP). Enhanced PRP adhesion leads to a prolonged and localized production of GFs, which is verified by platelet counting and by ELISA of vascular endothelial growth factors (VEGFs) and of platelet derived growth factors (PDGFs)...
September 7, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28873284/platelet-rich-plasma-ultrasound-guided-injection-in-the-treatment-of-carpal-tunnel-syndrome-a-placebo-controlled-clinical-study
#10
M-A Malahias, V S Nikolaou, E O Johnson, M-K Kaseta, S-T Kazas, G C Babis
PURPOSE: To demonstrate whether and to what extent a single injection of Platelet-Rich Plasma (PRP), under ultrasound guidance, can improve the clinical symptoms of patients with a mild to moderate carpal tunnel syndrome (CTS). METHODS: We conducted a prospective, randomized, clinical study including 50 patients suffering from mild to moderate CTS for a minimum duration of 3-months. Patients were randomly divided into two groups: A (26 patients) received an ultrasound-guided PRP injection into the carpal tunnel, whereas Group B (24 patients) was injected with placebo (0...
September 5, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28865187/sustained-release-of-multicomponent-platelet-rich-plasma-proteins-from-hydrolytically-degradable-peg-hydrogels
#11
Era Jain, Saahil Sheth, Andrew Dunn, Silviya P Zustiak, Scott A Sell
Platelet-rich plasma (PRP), an autologous blood derived product is a concentrated mix of multiple growth factors and cytokines. Direct injections of PRP are clinically used for treatment of various musculoskeletal disorders and in wound healing. However, PRP therapy has met with limited clinical success possibly due to unpredictable and premature bolus delivery of PRP growth factors. The objective of this study was to predictably control the bioavailability of PRP growth factors using a hydrolytically degradable polyethylene glycol (PEG) hydrogel...
September 2, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28863268/2-years-outcome-of-thread-lifting-with-absorbable-barbed-pdo-threads-innovative-score-for-objective-and-subjective-assessment
#12
Yasser Helmy Ali
BACKGROUND: Thread lifting rejuvenation procedures are re-evolved again, after developing of absorbable threads, with very popular spread among plastic surgeons and dermatologists but with little articles have been written in literature about absorbable threads. Objective to evaluate two years' outcome of absorbable barbed thread lifting used for facial rejuvenation. METHODS: Prospective comparative study both objectively and subjectively and follow up assessment for 24 months...
September 1, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28860871/first-in-man-intraglandular-implantation-of-stromal-vascular-fraction-and-adipose-derived-stem-cells-plus-platelet-rich-plasma-in-irradiation-induced-gland-damage-a-case-study
#13
Kristin Comella, Walter Bell
BACKGROUND: Stromal vascular fraction (SVF) is a mixture of cells which can be isolated from a mini-lipoaspirate of fat tissue. Platelet-rich plasma (PRP) is a mixture of growth factors and other nutrients which can be obtained from peripheral blood. Adipose-derived stem/stromal cells (ADSCs) can be isolated from fat tissue and expanded in culture. The SVF includes a variety of different cells such as ADSCs, pericytes, endothelial/progenitor cells, and a mix of different growth factors...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28859737/techniques-for-optimizing-surgical-scars-part-1-wound-healing-and-depressed-atrophic-scars
#14
Sailesh Konda, Kathryn Potter, Vicky Zhen Ren, Apphia Lihan Wang, Aditya Srinivasan, Suneel Chilukuri
Surgical management of benign or malignant cutaneous tumors may result in noticeable scars that are of great concern to patients, regardless of sex, age, or ethnicity. Techniques to optimize surgical scars are discussed in this three-part review. In part 1, an overview of the importance of preoperative planning, intraoperative technique, and pathophysiology of wound healing is followed by a discussion of scar revision options for depressed/atrophic scars. Scar revision options for these scars include dermabrasion, needling and subcision, punch excision and grafts, fillers, nonablative fractional lasers, ablative and fractional ablative lasers, and platelet-rich plasma (PRP)...
2017: Skinmed
https://www.readbyqxmd.com/read/28854761/platelet-rich-plasma-injections-as-a-treatment-for-refractory-patellar-tendinosis-a-meta-analysis-of-randomised-trials
#15
REVIEW
Leanne Dupley, Charalambos P Charalambous
Purpose: Patellar tendinosis (PT) is a common condition amongst athletes. In this study, we perform a meta-analysis on randomised controlled trials (RCTs) to evaluate the use of platelet-rich plasma (PRP) for refractory PT. Methods: A literature search was undertaken in various databases from their year of inception to October 2015. The primary outcome measure was the Victorian Institute of Sports Assessment-Patella (VISA-P) score. Results: We identified 2 RCTs comparing PRP injections to alternative treatment options (extracorporeal shockwave therapy [ESWT] and dry needling of the tendon)...
September 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28853968/evaluation-of-autologous-platelet-rich-plasma-plus-ablative-carbon-dioxide-fractional-laser-in-the-treatment-of-acne-scars
#16
Ahmed Mohammed Abdel Aal, Ibrahim Maeraj Ibrahim, Nevein Ahmed Sami, Ibrahim Mohammed Abdel Kareem
INTRODUCTION: Acne scar is a common distressing complication of acne vulgaris. CO2 laser resurfacing proved effective for treatment of such problem but the associated complications may limit its use. Platelet rich plasma (PRP) may increase the chance of favorable outcome. AIM OF THE WORK: To evaluate the synergistic effects of autologous PRP with fractional CO2 laser resurfacing in treatment of acne scars among Egyptian patients. PATIENTS AND METHOD: This study included 30 patients suffering from post-acne scars...
August 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28853913/comparison-of-the-effects-of-osteochondral-autograft-transplantation-with-platelet-rich-plasma-or-platelet-rich-fibrin-on-osteochondral-defects-in-a-rabbit-model
#17
Masahiro Maruyama, Hiroshi Satake, Tomoto Suzuki, Ryusuke Honma, Yasushi Naganuma, Yuya Takakubo, Michiaki Takagi
BACKGROUND: Although osteochondral autograft transplantation (OAT) provides satisfactory outcomes for osteochondral defects, for large defects OAT is often inadequate because of graft availability. Osteochondral allograft transplantation is an alternative treatment for large defects, but this approach is limited by graft storage constraints and carries disease transmission risks. Platelet-rich fibrin (PRF) is a second-generation platelet concentrate, and its positive effect on articular cartilage has been reported...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28852294/a-spilt-head-study-of-efficacy-of-placebo-versus-platelet-rich-plasma-injections-in-the-treatment-of-androgenic-alopecia
#18
Dilip Kachhawa, Gauri Vats, Durgesh Sonare, Pankaj Rao, Sandeep Khuraiya, Rohit Kataiya
BACKGROUND: Platelet-rich plasma (PRP) is an autologous concentration of human platelets contained in a small volume of plasma with haemostatic and tissue repairing effects. Being enriched by various growth factors, PRP has become the focus of attention in numerous fields of medicine. Androgenic alopecia (AGA) is a common chronic hair loss disorder, characterised by progressive hair loss. Despite the therapeutic options available, there is low patient compliance and satisfaction rate...
April 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28845088/platelet-rich-plasma-as-an-autologous-and-proangiogenic-cell-delivery-system
#19
Jessica Zahn, Markus Loibl, Christoph Sprecher, Michael Nerlich, Mauro Alini, Sophie Verrier, Marietta Herrmann
Angiogenesis is a key factor in early stages of wound healing and is crucial for the repair of vascularized tissues such as the bone. However, supporting timely revascularization of the defect site still presents a clinical challenge. Tissue engineering approaches delivering endothelial cells or prevascularized constructs may overcome this problem. In the current study, we investigated platelet-rich plasma (PRP) gels as autologous, injectable cell delivery systems for prevascularized constructs. PRP was produced from human thrombocyte concentrates...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28834191/combined-treatment-with-fractional-carbon-dioxide-laser-autologous-platelet-rich-plasma-and-narrow-band-ultraviolet-b-for-vitiligo-in-different-body-sites-a-prospective-randomized-comparative-trial
#20
Rania Abdelghani, Naglaa A Ahmed, Hanan M Darwish
BACKGROUND: Multiple treatment options are introduced in treatment of vitiligo but the response is unsatisfactory. OBJECTIVE: In this prospective, randomized, comparative trial, we studied the effect of combined treatment with fractional carbon dioxide (CO2 ) laser, platelet-rich plasma (PRP) injection, and narrowband ultraviolet B (NB-UVB) for stable nonsegmental vitiligo regarding repigmentation grade, patient's satisfaction, and side effects. METHODS: Eighty adult patients with localized nonsegmental vitiligo were enrolled in this study...
August 20, 2017: Journal of Cosmetic Dermatology
keyword
keyword
45976
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"