keyword
https://read.qxmd.com/read/38493485/digital-health-technologies-compounding-the-existing-ethical-challenges-of-the-right-not-to-know
#1
JOURNAL ARTICLE
Richard C Armitage
INTRODUCTION: Doctors hold a prima facie duty to respect the autonomy of their patients. This manifests as the patient's 'right' not to know when patients wish to remain unaware of medical information regarding their health, and poses ethical challenges for good medical practice. This paper explores how the emergence of digital health technologies might impact upon the patient's 'right' not to know. METHOD: The capabilities of digital health technologies are surveyed and ethical implications of their effects on the 'right' not to know are explored...
March 17, 2024: Journal of Evaluation in Clinical Practice
https://read.qxmd.com/read/38493447/clinical-practice-guidelines-for-molecular-tumor-marker-2nd-edition-review-part-2
#2
JOURNAL ARTICLE
Yoshinori Kikuchi, Hideaki Shimada, Fumiyuki Yamasaki, Taku Yamashita, Koji Araki, Kohei Horimoto, Satoshi Yajima, Masakazu Yashiro, Keigo Yokoi, Haruhiko Cho, Takuya Ehira, Kazunari Nakahara, Hiroshi Yasuda, Kazutoshi Isobe, Tetsu Hayashida, Shingo Hatakeyama, Koichiro Akakura, Daisuke Aoki, Hiroyuki Nomura, Yuji Tada, Yuki Yoshimatsu, Hayato Miyachi, Chiaki Takebayashi, Ichiro Hanamura, Hiroyuki Takahashi
In recent years, rapid advancement in gene/protein analysis technology has resulted in target molecule identification that may be useful in cancer treatment. Therefore, "Clinical Practice Guidelines for Molecular Tumor Marker, Second Edition" was published in Japan in September 2021. These guidelines were established to align the clinical usefulness of external diagnostic products with the evaluation criteria of the Pharmaceuticals and Medical Devices Agency. The guidelines were scoped for each tumor, and a clinical questionnaire was developed based on a serious clinical problem...
March 17, 2024: International Journal of Clinical Oncology
https://read.qxmd.com/read/38493442/impact-of-a-quality-improvement-initiative-and-monthly-multidisciplinary-meetings-on-outcomes-after-posterior-spinal-fusion-for-adolescent-idiopathic-scoliosis
#3
JOURNAL ARTICLE
Astrid C Hengartner, Aladine A Elsamadicy, Anshu Jonnalagadda, Samuel Craft, Josiah J Z Sherman, Benjamin C Reeves, Tiana Fernandez, Joshua Hobbs, Andrew B Koo, Michael DiLuna, Dominick A Tuason
INTRODUCTION: Several studies have demonstrated the benefits of enhanced recovery after surgery (ERAS) protocols for patients with adolescent idiopathic scoliosis (AIS) undergoing posterior spinal instrumented fusion (PSIF). However, there are relatively few studies investigating the effect of regular multidisciplinary team meetings on level selection, surgical performance parameters, and patient outcomes after PSIF for AIS. The aim of this study was to assess changes in intra- and postoperative outcomes following multidisciplinary team meeting implementation for patients undergoing PSIF for AIS...
March 17, 2024: Spine Deformity
https://read.qxmd.com/read/38493405/impact-of-replacing-fentanyl-with-hydromorphone-as-the-first-line-postoperative-opioid-among-patients-undergoing-outpatient-cancer-surgery
#4
JOURNAL ARTICLE
Jennifer R Majumdar, John Grbic, Sigrid Carlsson, Donna Barreiro, Marie Marte, Vincent Laudone, Melissa J Assel, Geema Masson
PURPOSE: In response to a nationwide fentanyl shortage, our institution assessed whether changing our first-line postoperative intravenous opioid from fentanyl to hydromorphone impacted patient outcomes. The primary research aim was to evaluate the association between first-line opioid and rapidity of recovery. DESIGN: The study team retrospectively obtained data on all consecutive patients extracted from the electronic medical record. The rapidity of recovery was defined as the time from entry into the postanesthesia care unit to the transition to Phase 2 for ambulatory extended recovery patients and as the length of total postanesthesia care unit stay for outpatients...
March 15, 2024: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://read.qxmd.com/read/38493375/coronavirus-disease-2019-infections-among-emergency-health-care-personnel-impact-on-delivery-of-united-states-emergency-medical-care-2020
#5
JOURNAL ARTICLE
Kurt D Weber, William Mower, Anusha Krishnadasan, Nicholas M Mohr, Juan Carlos Montoy, Robert M Rodriguez, Philip A Giordano, Patrick Ten Eyck, Karisa K Harland, Kelli Wallace, Lawrence Clifford McDonald, Preeta K Kutty, Elisabeth M Hesse, David A Talan
STUDY OBJECTIVE: In the early months of the coronavirus disease 2019 (COVID-19) pandemic and before vaccine availability, there were concerns that infected emergency department (ED) health care personnel could present a threat to the delivery of emergency medical care. We examined how the pandemic affected staffing levels and whether COVID-19 positive staff were potentially infectious at work in a cohort of US ED health care personnel in 2020. METHODS: The COVID-19 Evaluation of Risks in Emergency Departments (Project COVERED) project was a multicenter prospective cohort study of US ED health care personnel conducted from May to December 2020...
March 16, 2024: Annals of Emergency Medicine
https://read.qxmd.com/read/38493367/assessment-of-dosing-strategies-for-pediatric-drug-products
#6
JOURNAL ARTICLE
Zachary L Taylor, Francis G Green, Nayeem Hossain, Gilbert J Burckart, Michael Pacanowski, Robert N Schuck
Pediatric drug dosing is challenged by the heterogeneity of developing physiology and ethical considerations surrounding a vulnerable population. Often, pediatric drug dosing leverages findings from the adult population; however, recent regulatory efforts have motivated drug sponsors to pursue pediatric-specific programs to meet an unmet medical need and improve pediatric drug labeling. This paradigm is further complicated by the pathophysiological implications of obesity on drug distribution and metabolism and the roles that body composition and body size play in drug dosing...
March 17, 2024: Clinical Pharmacology and Therapeutics
https://read.qxmd.com/read/38493340/translational-bioinformatics-and-data-science-for-biomarker-discovery-in-mental-health-an-analytical-review
#7
JOURNAL ARTICLE
Krithika Bhuvaneshwar, Yuriy Gusev
Translational bioinformatics and data science play a crucial role in biomarker discovery as it enables translational research and helps to bridge the gap between the bench research and the bedside clinical applications. Thanks to newer and faster molecular profiling technologies and reducing costs, there are many opportunities for researchers to explore the molecular and physiological mechanisms of diseases. Biomarker discovery enables researchers to better characterize patients, enables early detection and intervention/prevention and predicts treatment responses...
January 22, 2024: Briefings in Bioinformatics
https://read.qxmd.com/read/38493336/genetics-providers-perspectives-on-the-use-of-digital-tools-in-clinical-practice
#8
JOURNAL ARTICLE
Whiwon Lee, Daena Hirjikaka, Sonya Grewal, Angela Shaw, Stephanie Luca, Marc Clausen, Yvonne Bombard, Robin Z Hayeems
BACKGROUND: Digital tools are increasingly incorporated into genetics practice to address challenges with the current model of care. Yet, genetics providers' perspectives on digital tool use are not well characterized. METHODS: Genetics providers across Canada were recruited. Semi-structured interviews were conducted to ascertain their perspectives on digital tool use and the clinical practice factors that might inform digital tool integration. A qualitative interpretive description approach was used for analysis...
March 13, 2024: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://read.qxmd.com/read/38493331/the-prevalence-of-post-traumatic-stress-disorder-as-part-of-post-icu-syndrome-among-israeli-icu-survivors
#9
JOURNAL ARTICLE
Shiri Zarour, Esther Dahan, Dana Karol, Or Hanoch, Barak Cohen, Idit Matot
BACKGROUND: Survivors of critical illness are at increased risk of long-term impairments, referred to as post-intensive care unit (ICU) syndrome (PICS). Post-traumatic stress disorder (PTSD) is common among ICU survivors with reported rates of up to 27%. The prevalence of PTSD among Israeli ICU survivors has not been reported to date. OBJECTIVES: To evaluate the prevalence of new onset PTSD diagnosed in a post-ICU clinic at a tertiary center in Israel. METHODS: We conducted a retrospective, single center, cohort study...
March 2024: Israel Medical Association Journal: IMAJ
https://read.qxmd.com/read/38493329/opioid-versus-benzodiazepine-based-sedation-for-mechanically-ventilated-patients-in-the-internal-medicine-ward
#10
JOURNAL ARTICLE
Natan Argaman, Avraham Meyer, Nisim Ifrach, Sara Dichtwald
BACKGROUND: Opioid-base sedation is considered the first line choice in ventilated patients in intensive care units (ICU). Few studies have examined sedation in ventilated patients outside the ICU. A pilot program was initiated in the internal medicine ward A at Meir Hospital in Kfar Saba, Israel. A new sedation protocol was implemented for opioid-based versus benzodiazepine-based sedation in ventilated patients. OBJECTIVES: To compare the rates and intensity of delirium between patients who received opioid-based sedation vs...
March 2024: Israel Medical Association Journal: IMAJ
https://read.qxmd.com/read/38493327/prognosis-of-patients-with-crohn-s-disease-and-ulcerative-colitis-following-percutaneous-coronary-intervention-procedures
#11
JOURNAL ARTICLE
Jill Savren Lotker, Ariel Roguin, Arthur Kerner, Erez Marcusohn, Ofer Kobo
BACKGROUND: Patients with inflammatory bowel disease (IBD) are at increased risk after percutaneous coronary intervention (PCI). OBJECTIVES: To compare the clinical outcomes within 30 days, one year, and five years of undergoing PCI. METHODS: We conducted a retrospective cohort study of adult patients with IBD who underwent PCI in a tertiary care center from January 2009 to December 2019. RESULTS: We included 44 patients, 26 with Crohn's disease (CD) and 18 with ulcerative colitis (UC), who underwent PCI...
March 2024: Israel Medical Association Journal: IMAJ
https://read.qxmd.com/read/38493326/clinical-characteristics-etiology-and-outcomes-of-hypothermia-in-well-appearing-children-referred-to-the-emergency-department
#12
JOURNAL ARTICLE
Lea Ohana Sarna, Dina Qaraen Saloni, Mevaseret Avital, Naama Pines, Itai Gross, Giora Wieser, Saar Hashvya
BACKGROUND: Hypothermia, as a sign of serious bacterial infection (SBI) in children and infants older than 90 days is poorly characterized, especially in the post-pneumococcal vaccine era. OBJECTIVES: To assess the prevalence of SBI in children and infants presenting to the pediatric emergency department (PED) with reported or documented hypothermia. METHODS: Retrospective data analysis was conducted of all well-appearing children aged 0-16 years who presented with a diagnosis of hypothermia at two tertiary PEDs from 2010 to 2019...
March 2024: Israel Medical Association Journal: IMAJ
https://read.qxmd.com/read/38493317/tele-urology-in-the-era-of-covid-19-an-experience-of-the-reconstructive-urology-department-in-iran
#13
JOURNAL ARTICLE
Jalil Hosseini, Amir Hossein Eslami, Shahrzad Nematollahi, Rayka Sharifian, Arezoo Sheikh Milani, Alireza Fatemi
INTRODUCTION: The outbreak of coronavirus has put additional pressure on the health care systems of many countries; but telemedicine can be an important way to deal with it, especially for people whose health has been affected by the virus. The present study aims to investigate the Implementation of a Tele-urology Program for Reconstructive Urologic Referrals: Initial Results and Patient Satisfaction. MATERIAL AND METHODS: All patients with a history of a urethral reconstructive surgery during last year was entered to our study and two nurses collected data of demographic and past medical history of patients by existed...
March 17, 2024: Urology Journal
https://read.qxmd.com/read/38493290/satisfaction-with-clinical-pathway-implementation-versus-job-performance-of-clinicians-empirical-evidence-on-the-mediating-role-of-work-engagement-from-public-hospitals-in-sichuan-china
#14
JOURNAL ARTICLE
Junlong Li, Lu Ao, Jay Pan
BACKGROUND: The job performance of clinicians is a clear indicator of both hospital capacity and the level of hospital service. It plays a crucial role in maintaining the effectiveness and quality of medical care. Clinical pathways are a systematic method of quality improvement successfully recommended by broader healthcare systems. Since clinicians play a key role in implementing clinical pathways in public hospitals, this study aims to investigate the effect of the satisfaction of clinicians in public hospitals with clinical pathway implementation on their job performance...
March 16, 2024: BMC Health Services Research
https://read.qxmd.com/read/38493094/awareness-and-healthcare-seeking-behavior-of-neonatal-danger-signs-and-predictor-variables-among-mothers-caregivers-in-four-developing-regional-state-of-ethiopia
#15
JOURNAL ARTICLE
Nagasa Dida, Lonsako Abute, Tariku Dejene, Tolasa Yadate, Temesgen Geleta, Rachana Sharma, Hnin Su Mon, Tesfaye Simireta, Hailemariam Addisu
INTRODUCTION: Mothers/caregivers should be aware of a newborn's danger signs and promptly seek medical attention. Hence, this study assessed mothers'/caregivers' awareness, healthcare seeking behaviors for neonatal danger signs and their determinants in the developing regional state of Ethiopia. METHODS: A community-based cross-sectional study was employed among mothers/caregivers of neonates in the developing regional state of Ethiopia. The sample was determined in collaboration with the Central Statistics Agency of Ethiopia...
March 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38493088/postnatal-care-and-acceptability-of-emollient-therapy-in-very-low-birthweight-infants-in-harare-zimbabwe-a-qualitative-analysis
#16
JOURNAL ARTICLE
Alexa Hui, Gwendoline Chimhini, Margaret Saungweme, Dorah Kaisi, Elisabeth Munetsi, Hilda A Mujuru, Gary L Darmstadt
BACKGROUND: Preterm birth (birth before 37 completed weeks of pregnancy) is the leading cause of neonatal and child under-five mortality globally, both of which are highest regionally in sub-Saharan Africa. The skin barrier plays a critical role in neonatal health and increasing evidence supports the use of topical emollient therapy to promote postnatal growth and reduce hospital-acquired infections in preterm infants. The World Health Organization (WHO) currently recommends emollient therapy in preterm or low birthweight infants globally but calls for further research on impacts of emollient use, especially in Africa...
March 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38493080/effectiveness-of-human-immunodeficiency-virus-prevention-strategies-by-mapping-the-geographic-dispersion-pattern-of-human-immunodeficiency-virus-prevalence-in-nanning-china
#17
JOURNAL ARTICLE
Ping Cen, Guo Xu, Jianxun Wu, Jiao Qin, Jinfeng He, Xiaofang Deng, Xi Yang, Peng Lu, Mengni Nong, Junjun Jiang, Li Ye, Hongyang Tang, Bingyu Liang, Hao Liang
BACKGROUND: The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) epidemics. However, the effectiveness of GACP in HIV prevention and treatment has rarely been reported. This study aimed to assess the effectiveness of the GACP implemented in Guangxi, China and provide data for strategy and praxis improvements to achieve Joint United Nations Programme on HIV/AIDS (UNAIDS) 95-95 targets...
March 16, 2024: BMC Public Health
https://read.qxmd.com/read/38493074/advances-in-immunotherapy-in-esophagogastric-cancer
#18
REVIEW
Khalid Jazieh, Harry Yoon, Mojun Zhu
Immune checkpoint inhibitors are rapidly transforming the care of patients with esophagogastric cancer. Particularly, anti-PD-1 therapy has demonstrated promising efficacy in metastatic and resectable disease. In this review, the authors discuss landmark clinical trials, highlight challenges and opportunities in this field, and propose potential directions for future work.
March 15, 2024: Hematology/oncology Clinics of North America
https://read.qxmd.com/read/38493047/the-frequency-of-pressure-injury-in-level-3-intensive-care-units-and-determination-of-risk-factors-a-cross-sectional-study
#19
JOURNAL ARTICLE
Refiye Akpolat, Hamide Sisman, Dudu Alptekin
AIM: This study was carried out to determine the prevalence of pressure injury and risk factors in patients hospitalized in a university hospital's level 3 intensive care unit. DESIGN: It is a descriptive, prospective, observational type study. METHOD: The sample of the study consisted of 176 patients aged 18 and over who were admitted to the intensive care units of a University Hospital for at least 24 h. Patient Information Form and Braden Risk Assessment Scale, Glasgow Coma Scale were used to collect data...
March 12, 2024: Journal of Tissue Viability
https://read.qxmd.com/read/38493024/college-health-centers-an-update-on-medical-issues
#20
JOURNAL ARTICLE
Ariel Tassy Nunez
College health centers are an important source of health care for large numbers of young adults throughout the country. With 16.9 million students enrolled in 2023 in post-secondary institutions in the United States, the potential impact that health centers at these institutions have is significant. Late adolescence and early adulthood is a particularly vulnerable stage of both cognitive and psychosocial development, and college health centers that provide comprehensive medical and mental-health care play an important role in providing comprehensive care for this age group...
March 15, 2024: Current Problems in Pediatric and Adolescent Health Care
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