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Kathryn Tinsley Anderson, Marisa A Bartz-Kurycki, Akemi L Kawaguchi, Mary T Austin, Galit Holzmann-Pazgal, Lillian S Kao, Kevin P Lally, Kuojen Tsao
BACKGROUND: The role of home discharge antibiotics in children after perforated appendicitis is unclear. This study evaluates the outcomes of complicated appendicitis patients being discharged with or without home antibiotics after initial surgery and in-patient treatment. STUDY DESIGN: The 2015 and 2016 National Surgical Quality Improvement-Pediatric (NSQIP-P) database was queried for patients <18 years of age with complicated appendicitis. Home antibiotics (HA) were prescribed or not (No Home Antibiotics- NHA)...
April 19, 2018: Journal of the American College of Surgeons
Marion Taleb, Nicolas Nardi, Alexis Arnaud, Nathalie Costet, Pierre-Yves Donnio, Charlotte Engrand, Edouard Habonimana, Eric Wodey, Pierre Tattevin
Acute appendicitis in children requires early surgery, and a short course of antibiotics active on Enterobacteriaceae and anaerobes. Although aminoglycoside-containing 3-drug regimen have been used successfully for decades, simpler regimens with similar efficacy are increasingly used. We aimed to evaluate the impact of a switch from the combination of cefotaxime, metronidazole, and gentamicin (regimen 1), to piperacillin-tazobactam (regimen 2), as first-line regimen for complicated acute appendicitis in children...
April 17, 2018: International Journal of Antimicrobial Agents
Jianling Li, Guohua Ding, Yanyan Niu, Luyong Wu, Huajie Feng, Wenying He
5-Methyl-2-phenyl-2H-1,2,3-triazole-4-carboxylic acid (MPTC), a newly synthesized compound, was explored to study the structural properties and theoretical spectra by using GaussView5.0 program package and the time dependent density functional theory (TD DFT). The calculated quantum chemical values suggested that it is easy for MPTC to lose electron with weak electron accepting ability. And the results of experimental measurements on fluorescence and absorption spectra were consistent with that of the calculated spectra in great degree...
April 11, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Attila Kormos, Christine Koehler, Eszter Fodor, Zsófia Rutkai, Maddison Martin, Gábor Mező, Edward Lemke, Péter Kele
Fluorogenic probes are capable of minimizing background fluorescence of unreacted and non-specifically adsorbed reagents. The preceding years have brought substantial developments in the design and synthesis of bioorthogonally applicable fluorogenic systems mainly based on the quenching effects of azide and tetrazine moieties. The modulation power exerted by these bioorthogonal motifs typically becomes less efficient on more conjugated systems, i.e. on probes with red-shifted emission wavelength. In order to reach efficient quenching, i...
April 20, 2018: Chemistry: a European Journal
Vellimalai Punitharasu, Munavvar Fairoos Mele Kavungathodi, Jayaraj Nithyanandhan
To synergize both steric and electronic factors in designing the dyes for dye-sensitized solar cells (DSSCs), a series of cis-configured unsymmetrical squaraine dyes P11-15 with suitably functionalized alkyl groups and electron withdrawing group containing squaric acid unit were synthesized, respectively. These dyes capture the importance of (i) the effect and position of branched alkyl groups, (ii) mono- and di-anchoring groups containing dyes and (iii) further appending alkyl groups through the cyanoester vinyl unit on the central squaric acid units of D-A-D based cis-configured squaraine dyes...
April 20, 2018: ACS Applied Materials & Interfaces
Yves Bousquet
Despite the title page is dated 1795, the fourth volume of Olivier's Entomologie, ou histoire naturelle des insectes was issued in two parts, one probably in 1795 and the second in 1800. All new taxa made available in this work have previously been dated 1795 in the literature. A list of new species described in 1795 and a list of those that have to be dated 1800 are appended. The genus Necrobia should be credited to Latreille, 1797, not Olivier, 1795.
2018: ZooKeys
Tiffany J Zens, Andrew P Rogers, Erica L Riedesel, Charles M Leys, Daniel J Ostlie, Michael A Woods, Kara G Gill
INTRODUCTION: Contrast-enhanced CT remains the first-line imaging for evaluating postoperative abscess (POA) after appendicitis. Given concerns of ionizing radiation use in children, we began utilizing quick MRI to evaluate POA and summarize our findings in this study. MATERIALS AND METHODS: Children imaged with quick MRI from 2015 to 2017 were compared to children evaluated with CT from 2012 to 2014 using an age and weight matched case-control model. Radiation exposure, size and number of abscesses, length of exam, drain placement, and patient outcomes were compared...
March 6, 2018: Journal of Pediatric Surgery
Siyang Liu, Pengju Lin, Fangfang Niu, Pengju Zeng, Bin Zhang
A series of symmetric carbazole derivatives (CzP-H, CzP-CN, CzP-Me, and CzP-OMe), which comprise electron-donating and electron-drawing groups appending on a phenyl core, was synthesized and characterized in detail. These compounds exhibit excellent thermal stabilities, with thermal decomposition temperatures exceeding 400 &deg;C. From the fluorescent spectra in film, CzP-H, CzP-Me, and CzP-OMe showed UV to blue-violet emission, with peaks at 396 nm, 402 nm, and 392 nm, respectively. The E 00 energies of CzP-H, CzP-CN, CzP-Me, and CzP-OMe were 3...
April 17, 2018: Materials
Chijioke Chinaka, Shahbaz Mansoor, Mohamed Salaheidin
Acute abdominal pain is a common surgical presentation, and most often, the first line of consideration is to rule out acute appendicitis; this is more so when the patient is an adolescent or within younger age group. In most cases, other differentials are considered before omental torsion. Omental torsion is a cause of acute abdominal pain and sometimes mimics acute appendicitis in its presentation. We present a case of a 14-yr-old boy who presented with acute abdomen with symptoms mimicking acute appendicitis...
2018: Case Reports in Surgery
Tatiana Thom, Deanne Leonard, Peter Fitzpatrick, Nabeel Aslam
Acute appendicitis in peritoneal dialysis patients generally presents as abdominal pain and cloudy dialysate. We report a case of acute appendicitis in a peritoneal dialysis patient that presented as poor dialysate fluid drainage and an abnormal abdominal X-ray showing breakage in the continuity of the catheter. Catheter dysfunction in this case was caused by acute appendicitis leading to the formation of adhesions with peritoneal dialysis catheter trapped in it. This resulted in radiological appearance of catheter breakage, although catheter itself was intact...
April 17, 2018: BMJ Case Reports
Mohamed Zouari, Hamid Louati, Imen Abid, Fatma Trabelsi, Mahdi Ben Dhaou, Mohamed Jallouli, Riadh Mhiri
BACKGROUND: Enterobius vermicularis (EV) is the most common helminthic infection in the world. This small parasite is predominant in the pediatric population. The presence of EV in the appendix can cause or mimick appendicitis. The aim of our study was to compare patients with EV infection and those without EV infection, and to identify predictive factors that may help the diagnosis of EV infection in patients presenting with right iliac fossa pain and avoid negative appendectomy. METHODS: A retrospective analysis of all the appendices removed between January 2012 and December 2016 was conducted at the department of pediatric surgery, Hedi Chaker Hospital, Sfax, Tunisia...
February 1, 2018: Archives of Iranian Medicine
Ming-Xing Zhang, Jing Zhang, Jun Yin, František Hartl, Sheng Hua Liu
Two related three-membered series of nonlinear aminophenylferrocene and diphenylaminoferrocene complexes were prepared and characterized by 1H and 13C NMR spectroscopy. The first series consists of 4-(diphenylamino)phenylferrocene (TPA-Fc, 1a), its dimethoxy-substituted tetraphenylphenylenediamine derivative (M2TPPD-Fc, 1c), and the triphenylamine-bridged bis(ferrocenyl) complex (Fc-TPA-Fc, 1b). The second series involves bis(4-methoxyphenyl)aminoferrocene (M2DPA-Fc, 1d), 4-methoxyphenylaminoferrocene (MPA-Fc) with N-phenyl-appended terminal TPA (1e), and the corresponding bis(MPA-Fc) complex with bridging TPA (1f)...
April 17, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
A L van den Boom, E M L de Wijkerslooth, K A L Mauff, I Dawson, C C van Rossem, B R Toorenvliet, B P L Wijnhoven
BACKGROUND: The intraoperative classification of appendicitis dictates the patient's postoperative management. Prolonged antibiotic prophylaxis is recommended for complex appendicitis (gangrenous, perforated, abscess), whereas preoperative prophylaxis suffices for simple appendicitis. Distinguishing these two conditions can be challenging. The aim of this study was to assess interobserver variability in the classification of appendicitis during laparoscopy. METHODS: Short video recordings taken during laparoscopy for suspected appendicitis were shown to surgeons and surgical residents...
April 16, 2018: British Journal of Surgery
Camille Lupiañez-Merly, Stephanie C Torres-Ayala, Lorena Morales, Adel Gonzalez, José A Lara-Del Rio, Ivonne Ojeda-Boscana
BACKGROUND Appendicitis is the most common cause of abdominal pain requiring emergent surgical intervention. Although typically presenting as right lower-quadrant pain, in rare cases it may present as left upper-quadrant pain secondary to abnormal position due to intestinal malrotation. Since atypical presentations may result in diagnostic and management delay, increasing morbidity and mortality, accurate and prompt diagnosis is important. Therefore, acute appendicitis should be considered in the differential diagnosis of left upper-quadrant abdominal pain...
April 16, 2018: American Journal of Case Reports
Anastasia Prodromidou, Nikolaos Machairas, Ioannis D Kostakis, Ernesto Molmenti, Eleftherios Spartalis, Athanasios Kakkos, Georgios T Lainas, Georgios C Sotiropoulos
OBJECTIVES: Acute appendicitis is the most prevalent cause of non-obstetrical surgical disease during pregnancy. There is no consensus on the optimal surgical management of acute appendicitis in pregnancy. Our aim is to identify surgical and obstetrical outcomes of laparoscopic (LA) and open approach (OA) in pregnant patients with acute appendicitis. STUDY DESIGN: Medline, Scopus, Google Scholar, Cochrane CENTRAL Register of Controlled Trials and Clinicaltrials...
April 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
H S Kim, H J Yeo, D H Shin, W H Cho, D Kim
Invasive aspergillosis is an important cause of morbidity and mortality in patients who have undergone lung transplantation. Aspergillus infections usually involve the respiratory tract, with vascular invasion and subsequent dissemination. However, acute appendicitis associated with localized aspergillosis is rare, especially among patients who have undergone prophylaxis with voriconazole. We present a case of primary Aspergillus appendicitis diagnosed by histologic examination in a patient who underwent lung transplantation...
April 11, 2018: Transplantation Proceedings
Chu Woon Ng, Anna Sandstrom, Grace Lim
BACKGROUND: Hernias of the posterior rectus sheath are very rare abdominal wall hernias with only a handful of cases reported in the literature to date. As an uncommon disease, it is important to recognize and report this case in order to enhance scientific knowledge of this disease. CASE PRESENTATION: This case report presents a spontaneous posterior rectus sheath herniation in a 79-year-old white man with previous abdominal surgery for appendicitis. His herniation was discovered incidentally during an examination for his chief complaints of lower abdominal pain and diarrhea which were later diagnosed as Salmonella-related gastroenteritis...
April 15, 2018: Journal of Medical Case Reports
Taiki Kijima, Hideto Hayashi, Hikari Chijimatsu, Yasunori Yoshimoto, Katsuhiko Morita, Kouichiro Sakata, Mihoko Setoguchi
We report a case of appendicitis with an abscess that was treated with single-incision laparoscopic ileocecal resection with D2 lymphadenectomy because of intraoperative suspicion of appendiceal cancer. A 73-year-old woman was admitted to the hospital because of right lower abdominal pain. She was diagnosed with appendicitis with an abscess. Although single-incision laparoscopic appendectomy was planned, appendiceal cancer was suspected from intraoperative findings. Therefore, we performed single-incision laparoscopic ileocecal resection with D2 lymphadenectomy...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Zhe Liu, Xiangdong He, Meng Tian, Xicheng Liu, Yanhua Tang, Changfang Shao, Peiwei Gong, Jinfeng Liu, Shumiao Zhang, Lihua Guo
Organometallic half-sandwich IrIII complexes of type [(η5-Cpx)Ir(N^N)Cl]PF6 (Cpx: Cp* or its phenyl Cpxph or biphenyl Cpxbiph derivatives, N^N: triphenylamine (TPA) substituted bipyridyl ligand groups) have been synthesized and characterized. The complexes showed excellent BSA and DNA binding properties, and oxidize NADH to NAD+ efficiently. Complexes can induce apoptosis effectively and led to the emergence of reactive oxygen species (ROS) in cells. All complexes showed potent cytotoxicity with IC50 values ranging from 1...
April 12, 2018: Chemistry, An Asian Journal
Mehmet Emin Gunes, Feyzullah Ersoz, Yigit Duzkoylu, Soykan Arikan, Coskun Cakir, Ali Emre Nayci
Introduction: Appendectomy is still the most commonly performed intra-abdominal operation worldwide. Interestingly, it has not reached the same popularity as other laparoscopic surgical procedures. Although multiple techniques have been described, a standard approach has not been described for the laparoscopic technique yet. Aim: To perform hybrid appendectomy for acute appendicitis on McBurney's point, aiming to perform an easier and quicker procedure while limiting the trauma to the abdominal wall by obtaining the advantages of both laparoscopic and open techniques...
March 2018: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
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