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https://www.readbyqxmd.com/read/28195651/early-estimates-of-seer-cancer-incidence-2014
#1
Denise Riedel Lewis, Huann-Sheng Chen, Myles G Cockburn, Xiao-Cheng Wu, Antoinette M Stroup, Douglas N Midthune, Zhaohui Zou, Martin F Krapcho, Daniel G Miller, Eric J Feuer
BACKGROUND: Cancer incidence rates and trends for cases diagnosed through 2014 using data reported to the Surveillance, Epidemiology, and End Results (SEER) program in February 2016 and a validation of rates and trends for cases diagnosed through 2013 and submitted in February 2015 using the November 2015 submission are reported. New cancer sites include the pancreas, kidney and renal pelvis, corpus and uterus, and childhood cancer sites for ages birth to 19 years inclusive. METHODS: A new reporting delay model is presented for these estimates for more consistent results with the model used for the usual November SEER submissions, adjusting for the large case undercount in the February submission...
February 14, 2017: Cancer
https://www.readbyqxmd.com/read/28152885/creating-an-online-resource-providing-hospital-cancer-surgery-volumes-in-california
#2
Laurence C Baker, Jennifer Malin, Joseph Parker, Merry Holliday-Hanson, Niya Fong, Stephanie Teleki, Lance Lang, Maryann O'Sullivan
: 172 Background: Little evidence is available to help patients and providers, payers and policymakers find the highest-quality hospitals for cancer surgery. We initiated a groundbreaking effort in California ( www.calqualitycare.org ) to publicly report hospital cancer surgery volume data online. METHODS: With financial support from the nonprofit California HealthCare Foundation, we assembled a multidisciplinary team to oversee the project and ensure sound methodology...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28120274/advanced-gi-surgery-training-a-roadmap-for-the-future-the-white-paper-from-the-ssat-task-force-on-advanced-gi-surgery-training
#3
Matthew M Hutter, Kevin E Behrns, Nathaniel J Soper, Fabrizio Michelassi
There is the need for well-trained advanced GI surgeons. The super specialization seen in academic and large community centers may not be applicable for surgeons practicing in other settings. The pendulum that has been swinging toward narrow specialization is swinging the other way, as many trained subspecialists are having a harder time finding positions after fellowship, and if they do find a position, the majority of their practice can actually be advanced GI surgery and not exclusively their area of focused expertise...
January 24, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28106907/subsequent-malignancies-among-long-term-survivors-of-hodgkin-lymphoma-and-non-hodgkin-lymphoma-a-pooled-analysis-of-german-cancer-registry-data-1990-2012
#4
Nadia Baras, Stefan Dahm, Jörg Haberland, Martin Janz, Katharina Emrich, Klaus Kraywinkel, Abdulgabar Salama
The increased risk of subsequent primary malignancies (SPM) in survivors of adult-onset Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) remains a challenging clinical problem worldwide. The German cancer registry database, pooled from 14 federal states, was used to calculate the standardized incidence ratio (SIR) and excess absolute risk (EAR) of SPM in 128 587 patients registered with first primary HL/NHL between 1990 and 2012. Conversely, SIRs were also calculated for a subsequent HL/NHL following other first cancers...
January 20, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/27987098/a-surgical-department-for-intensified-care
#5
Pierluigi di Sebastiano, Tommaso Grottola, Anna Maysse, Maria Marino, Francesco Zavattaro, Pas Quale Flacco, F Francesco di Mola
PURPOSE: The growing pressure to rationalize costs in the healthcare system demands the development of new healthcare models aimed at allowing patients to receive the best treatment, without ignoring the rising costs. METHODS: In the Healthcare Unit 2 located in the Abruzzo region in Italy, a new model of intensified care surgical department was designed in January 2013. The department was based on the selection of the degree of patient disease. Patients requiring a medium-low degree surgery were treated in the peripheral unit, in the Ortona hospital, while more complex surgical procedures, most cancer cases (including stomach, liver, pancreas, colon-rectum or multi-organ resections), were performed in the central unit in the Chieti hospital...
December 16, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27908924/excess-weight-as-a-risk-factor-common-to-many-cancer-sites-words-of-caution-when-interpreting-meta-analytic-evidence
#6
Melina Arnold, Andrew G Renehan, Graham A Colditz
For over a decade, excess body weight, commonly categorized as overweight (body mass index, BMI: 25.0 to 29.9 kg/m2) and obesity (BMI: ≥ 30 kg/m2) has been an established incidence risk factor for several adult cancers (1). For 2012, the burden of disease attributed to elevated BMI was estimated as nearly half-million new cancers worldwide, making this the third highest ranked cancer risk factor globally after smoking and infections (ranked second in most western populations) and an important public health problem (2, 3)...
December 1, 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27832048/vital-signs-disparities-in-tobacco-related-cancer-incidence-and-mortality-united-states-2004-2013
#7
S Jane Henley, Cheryll C Thomas, Saida R Sharapova, Behnoosh Momin, Greta M Massetti, Deborah M Winn, Brian S Armour, Lisa C Richardson
BACKGROUND: Tobacco use causes at least 12 types of cancer and is the leading preventable cause of cancer. METHODS: Data from the United States Cancer Statistics dataset for 2004-2013 were used to assess incidence and death rates and trends for cancers that can be caused by tobacco use (tobacco-related cancers: oral cavity and pharynx; esophagus; stomach; colon and rectum; liver; pancreas; larynx; lung, bronchus, and trachea; kidney and renal pelvis; urinary bladder; cervix; and acute myeloid leukemia) by sex, age, race, ethnicity, state, county-level poverty and educational attainment, and cancer site...
November 11, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27812075/can-a-diabetic-foot-be-malignant
#8
Muhammad Shoaib Zaidi, Asim Hassan, Samir Ouizi
Diabetes has been linked with malignancies like colon, rectum, liver, biliary tract, pancreas, kidney, leukaemia and melanoma. Melanoma can sometimes manifest as a diabetic foot ulcer.We describe an elderly male with Type 2 diabetes, who had presented to us with a non-healing wound at the right heel, that later turned out to be an invasive malignant melanoma.
November 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27775254/the-burden-of-cancer-in-korea-during-2012-findings-from-a-prevalence-based-approach
#9
Young Hoon Gong, Seok Jun Yoon, Min Woo Jo, Arim Kim, Young Ae Kim, Jihyun Yoon, Hyeyoung Seo, Dongwoo Kim
Cancer causes a significant deterioration in health and premature death and is a national socioeconomic burden. This study aimed to measure the burden of cancer using the disability-adjusted life year (DALY) metric based on the newly adopted methodology from the Global Burden of Disease Study in 2010. This study was conducted based on data from the Korean National Cancer Registry. The DALYs were calculated using a prevalence-based method instead of the incidence-based method used by previous studies. The total burden of cancer in 2012 was 3,470...
November 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27766816/synchronous-dual-primary-malignancies-of-liver-and-pancreas-with-colonic-metastasis-an-unique-presentation
#10
Nitin R Gaikwad, Sudhir J Gupta, Amol R Samarth, Tushar H Sankalecha
Synchronous appearance of the primary gastrointestinal malignancies is rare. Coexistence of primary pancreatic and hepatocellular carcinoma as synchronous malignancy is even rarer. We report a case of such combination in a 50 year old female who presented with bleeding per rectum and while evaluating we found simultaneous appearance of primary malignancies of pancreas, liver and solitary colonic metastasis from the pancreas in the background of chronic calcific pancreatitis. To the best of our knowledge this combination of synchronous pancreatic and hepatocellular carcinoma and colonic metastasis from the pancreas is unique...
October 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27601510/public-reporting-of-hospital-level-cancer-surgical-volumes-in-california-an-opportunity-to-inform-decision-making-and-improve-quality
#11
Christina A Clarke, Steven M Asch, Laurence Baker, Karl Bilimoria, R Adams Dudley, Niya Fong, Merry L Holliday-Hanson, David S P Hopkins, Elizabeth M Imholz, Jennifer Malin, Lisa Moy, Maryann O'Sullivan, Joseph P Parker, Christopher S Saigal, Bruce Spurlock, Stephanie Teleki, David Zingmond, Lance Lang
PURPOSE: Most patients, providers, and payers make decisions about cancer hospitals without any objective data regarding quality or outcomes. We developed two online resources allowing users to search and compare timely data regarding hospital cancer surgery volumes. METHODS: Hospital cancer surgery volumes for all California hospitals were calculated using ICD-9 coded hospital discharge summary data. Cancer surgeries included (bladder, brain, breast, colon, esophagus, liver, lung, pancreas, prostate, rectum, and stomach) were selected on the basis of a rigorous literature review to confirm sufficient evidence of a positive association between volume and mortality...
September 6, 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27543725/solitary-colon-metastasis-from-renal-cell-carcinoma-nine-years-after-nephrectomy-a-case-report
#12
Elaine Vo, Carlos H Palacio, Ronald Omino, Richard E Link, Yvonne Sada, Artinyan Avo
INTRODUCTION: Renal cell carcinoma (RCC) is the most common renal malignancy in adults. Metastatic disease is relatively common at presentation and frequently involves the lung, bone, brain, liver and adrenal glands. After curative resection, there is a 30-40% risk of recurrence, and a 10% risk of developing metastatic disease after 5 years. The gastrointestinal tract, particularly the colon, represents a very uncommon site of late metastatic disease. PRESENTATION OF CASE: We present a case of a 67 year-old-male who underwent a left radical nephrectomy for RCC 9 years before presenting with a metastatic large bowel obstruction...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27543724/odd-localisation-for-a-gastric-cancer-histology
#13
Paulina Kuczma, Jordi Vidal Fortuny, Saiji Essia, Ariane de Lassus, Philippe Morel, Frédéric Ris
INTRODUCTION: More than 96% of signet-ring cell carcinomas occur in the stomach and the rest in other organs, including the gallbladder, pancreas, urinary bladder and breast. Primary signet-ring cell carcinoma of the colon and rectum is very rare, accounting for 0.1%-2.4% of all colorectal cancers. PRESENTATION OF CASE: We report a case of a 55-year old man who is operated for a caecal mass evocative of an appendicitis abscess. Intraoperatively, we discover a large, ulcerated ilio-caecal mass with several lymphadenopathies...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27500145/high-intensity-focused-ultrasound-hifu-applied-to-hepato-bilio-pancreatic-and-the-digestive-system-current-state-of-the-art-and-future-perspectives
#14
REVIEW
Michele Diana, Luigi Schiraldi, Yu-Yin Liu, Riccardo Memeo, Didier Mutter, Patrick Pessaux, Jacques Marescaux
BACKGROUND: High intensity focused ultrasound (HIFU) is emerging as a valid minimally-invasive image-guided treatment of malignancies. We aimed to review to current state of the art of HIFU therapy applied to the digestive system and discuss some promising avenues of the technology. METHODS: Pertinent studies were identified through PubMed and Embase search engines using the following keywords, combined in different ways: HIFU, esophagus, stomach, liver, pancreas, gallbladder, colon, rectum, and cancer...
August 2016: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/27326246/genomic-profiling-of-metastatic-gastroenteropancreatic-neuroendocrine-tumor-gep-net-patients-in-the-personalized-medicine-era
#15
Seung Tae Kim, Su Jin Lee, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Jeeyun Lee, Young Suk Park
BACKGROUND: We have conducted molecular profiling through a high-throughput molecular test as part of our clinical practice for patients with advanced gastrointestinal (GI) cancer or rare cancers including gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Herein, we report on the molecular characterization of 14 metastatic GEP-NET patients. METHODS: We conducted the Ion AmpliSeq Cancer Hotspot Panel v2 (detecting 2,855 oncogenic mutations in 50 commonly mutated genes) and nCounter Copy Number Variation Assay, which was designed with 21 genes based on available targeted agents, as a high throughput genomic platform in 14 patients with metastatic GEP-NETs...
2016: Journal of Cancer
https://www.readbyqxmd.com/read/27321059/epidemiological-evidence-on-environmental-tobacco-smoke-and-cancers-other-than-lung-or-breast
#16
Peter N Lee, Alison J Thornton, Janette S Hamling
We reviewed 87 epidemiological studies relating environmental tobacco smoke (ETS) exposure to risk of cancer other than lung or breast in never smoking adults. This updates a 2002 review which also considered breast cancer. Meta-analysis showed no significant relationship with ETS for nasopharynx cancer, head and neck cancer, various digestive cancers (stomach, rectum, colorectal, liver, pancreas), or cancers of endometrium, ovary, bladder and brain. For some cancers (including oesophagus, colon, gall bladder and lymphoma) more limited data did not suggest a relationship...
October 2016: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/27303130/carcinoid-tumour-of-caecum-an-unusual-palpable-mass-in-the-right-iliac-fossa
#17
Mohit M Agrawal, Nandkishor S Sude
Carcinoid tumour represents 0.8-1.5 % of malignant digestive tumours. Gastrointestinal (GI) carcinoids account for 95 % of all the carcinoids, and caecal carcinoids account for 5 % of all the carcinoids. These tumours are frequent in women (2-4:1) as reported by Spallitta and Termine (Minerva Chir 55:77-87, 2002). In order of frequency, they may occur in the appendix (35 %), ileum (28 %), rectum (13 %) and bronchi. Incidence is less than 1 % in the pancreas, gall bladder, liver, larynx, testes and ovaries...
April 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/27257115/time-dependent-risk-of-cancer-after-a-diabetes-diagnosis-in-a-cohort-of-2-3-million-adults
#18
Rachel Dankner, Paolo Boffetta, Ran D Balicer, Lital Keinan Boker, Maya Sadeh, Alla Berlin, Liraz Olmer, Margalit Goldfracht, Laurence S Freedman
Using a time-dependent approach, we investigated all-site and site-specific cancer incidence in a large population stratified by diabetes status. The study analyzed a closed cohort comprised of Israelis aged 21-89 years, enrolled in a health fund, and followed from 2002 to 2012. Adjusting for age, ethnicity, and socioeconomic status, we calculated hazard ratios for cancer incidence using Cox regression separately for participants with prevalent and incident diabetes; the latter was further divided by time since diabetes diagnosis...
June 15, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27247498/cancer-mortality-projections-in-korea-up-to-2032
#19
Mia Son, Jae-Won Yun
Predicting cancer mortality is important to estimate the needs of cancer-related services and to prevent cancer. Despite its significance, a long-term future projection of cancer mortality has not been conducted; therefore, our objective was to estimate future cancer mortality in Korea by cancer site through 2032. The specially designed Nordpred software was used to estimate cancer mortality. The cancer death data from 1983 to 2012 and the population projection data from 1983 to 2032 were obtained from the Korean National Statistics Office...
June 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/26951748/italian-cancer-figures-report-2015-the-burden-of-rare-cancers-in-italy
#20
Susanna Busco, Carlotta Buzzoni, Sandra Mallone, Annalisa Trama, Marine Castaing, Francesca Bella, Rosalba Amodio, Sabrina Bizzoco, Tiziana Cassetti, Claudia Cirilli, Rosanna Cusimano, Roberta De Angelis, Mario Fusco, Gemma Gatta, Valerio Gennaro, Adriano Giacomin, Paolo Giorgi Rossi, Lucia Mangone, Salvatore Mannino, Silvia Rossi, Daniela Pierannunzio, Andrea Tavilla, Sandro Tognazzo, Rosario Tumino, Massimo Vicentini, Maria Francesca Vitale, Emanuele Crocetti, Luigino DalMaso
OBJECTIVES This collaborative study, based on data collected by the network of Italian Cancer Registries (AIRTUM), describes the burden of rare cancers in Italy. Estimated number of new rare cancer cases yearly diagnosed (incidence), proportion of patients alive after diagnosis (survival), and estimated number of people still alive after a new cancer diagnosis (prevalence) are provided for about 200 different cancer entities. MATERIALS AND METHODS Data herein presented were provided by AIRTUM population- based cancer registries (CRs), covering nowadays 52%of the Italian population...
January 2016: Epidemiologia e Prevenzione
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