keyword
https://read.qxmd.com/read/38547335/impact-of-iodine-supply-in-infancy-and-childhood
#1
JOURNAL ARTICLE
Dominique Turck
PURPOSE OF REVIEW: To assess the most relevant articles on the impact of iodine supply in at-risk populations, namely infants and young children, pregnant and lactating women. RECENT FINDINGS: The 2022 Iodine Global Network Annual Report confirmed the dramatic decrease of severe iodine deficiency over the last 30 years, thanks to universal iodine iodization. However, mild to moderate deficiency is still present in many countries, where recent data showed a decrease of iodine intake and an impairment of iodine status...
March 28, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38547331/circulating-factors-in-cancer-cachexia-recent-opportunities-for-translational-research
#2
JOURNAL ARTICLE
Marina de Castro Coêlho, Giovana Parreira de Aquino, Amanda Soares Santos, Marilia Seelaender
PURPOSE OF REVIEW: To discuss the recent discoveries and limitations of the available literature on emerging circulating biomarkers of cancer cachexia. RECENT FINDINGS: Studies on circulating factors in cancer cachexia show promising alternatives for diagnosing the syndrome in a minimally invasive manner in the clinic setting, as well as potential targets for cancer cachexia treatment. Factors secreted by the tumor and the adipose tissue, such as extracellular vesicles and soluble proteins, respectively, have been shown to either directly induce wasting in vitro and in vivo or to be altered in the cachectic phenotype...
March 27, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38547330/evidence-on-docosahexaenoic-acid-and-arachidonic-acid-supplementation-for-preterm-infants
#3
JOURNAL ARTICLE
Alexandre Lapillonne, Chiara Lembo, Sissel J Moltu
PURPOSE OF REVIEW: For many decades, docosahexaenoic acid (DHA) supplementation was tested in premature infants to achieve an intake equivalent to the average level in breast milk, but this approach has led to conflicting results in terms of development and health outcomes. Higher doses of DHA closer to fetal accumulation may be needed. RECENT FINDINGS: The efficacy of DHA supplementation for preterm infants at a dose equivalent to the estimated fetal accumulation rate is still under investigation, but this may be a promising approach, especially in conjunction with arachidonic acid supplementation...
March 18, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38547323/sarcopenic-obesity-and-the-impact-on-bone-health
#4
JOURNAL ARTICLE
Silvia Migliaccio, Edoardo Mocini, Marianna Minnetti, Lorenzo Maria Donini
PURPOSE OF THE REVIEW: Sarcopenic obesity is a newly identified pathological entity defined by an increase in body fat mass with an associated sarcopenia, characterized by loss of muscle mass, strength, and function. Recently, the concomitant presence of skeletal alteration with sarcopenic obesity has been described leading to a new clinical entity defined osteosarcopenic obesity (OSO). Many studies have tried to unravel the metabolic complex mechanism leading to this clinical entity in order to understand the pathophysiology of this complex condition with the aim of posing an early diagnosis to improve the therapeutic approaches...
March 20, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38547234/transcriptome-wide-analysis-of-the-differences-between-mcf7-cells-cultured-in-dmem-or-%C3%AE-mem
#5
JOURNAL ARTICLE
Yang Jiao, Hongbo Zhao, Lin Lu, Xiangyu Zhao, Yanchun Wang, Bingrong Zheng
MCF7 cells have been used as an experimental model for breast cancer for decades. Typically, a culture medium is designed to supply cells with the nutrients essential for their continuous proliferation. Each medium has a specific nutritional composition. Therefore, cells cultured in different media may exhibit differences in their metabolism. However, only a few studies have investigated the effects of media on cells. In this study, we compared the effects of Dulbecco's modified Eagle medium (DMEM) and minimum essential medium alpha modification (αMEM) on MCF7 cells...
2024: PloS One
https://read.qxmd.com/read/38547211/short-term-chemotherapy-related-complications-and-undernutrition-in-children-diagnosed-with-cancer-at-korle-bu-teaching-hospital-accra-ghana-a-prospective-cohort-study
#6
JOURNAL ARTICLE
Nihad Salifu, Catherine I Segbefia, Yakubu Alhassan, Lorna A Renner, Edem M A Tette
Undernutrition in children with cancer is associated with complications during cancer therapy. The study objective was to determine the association between specific anthropometric parameters and short-term chemotherapy-related complications and mortality. This was a hospital-based, prospective cohort study of children, age ≤12 years, with a new cancer diagnosis at the Paediatric Oncology Unit, Korle Bu Teaching Hospital, Ghana. Socio-demographic information, cancer characteristics and anthropometric measurements were obtained at enrolment...
2024: PloS One
https://read.qxmd.com/read/38547208/metabolomic-response-to-acute-resistance-exercise-in-healthy-older-adults-by-1h-nmr
#7
JOURNAL ARTICLE
Darya Moosavi, Ivan Vuckovic, Hawley E Kunz, Ian R Lanza
BACKGROUND: The favorable health-promoting adaptations to exercise result from cumulative responses to individual bouts of physical activity. Older adults often exhibit anabolic resistance; a phenomenon whereby the anabolic responses to exercise and nutrition are attenuated in skeletal muscle. The mechanisms contributing to age-related anabolic resistance are emerging, but our understanding of how chronological age influences responsiveness to exercise is incomplete. The objective was to determine the effects of healthy aging on peripheral blood metabolomic response to a single bout of resistance exercise and whether any metabolites in circulation are predictive of anabolic response in skeletal muscle...
2024: PloS One
https://read.qxmd.com/read/38547207/effects-of-the-momentum-project-on-postpartum-family-planning-norms-and-behaviors-among-married-and-unmarried-adolescent-and-young-first-time-mothers-in-kinshasa-a-quasi-experimental-study
#8
JOURNAL ARTICLE
Anastasia J Gage, Francine E Wood, Rianne Gay, Pierre Akilimali
This study evaluated the effect of Momentum-an integrated family planning, maternal and newborn health, and nutrition intervention-on postpartum family planning norms and behaviors among ever married and never-married first-time mothers age 15-24 in Kinshasa, Democratic Republic of the Congo. Using data collected in 2018 and 2020, we conducted an intent-to-treat analysis among 1,927 first-time mothers who were about six-months pregnant at enrollment. Difference-in-differences models were run for panel data and treatment effects models with inverse-probability weighting for endline-only outcomes...
2024: PloS One
https://read.qxmd.com/read/38547113/low-birth-weight-household-socio-economic-status-water-and-sanitation-are-associated-with-stunting-and-wasting-among-children-aged-6-23-months-results-from-a-national-survey-in-ghana
#9
JOURNAL ARTICLE
Hammond Yaw Addae, Mohammed Sulemana, Taminu Yakubu, Ambrose Atosona, Rafatu Tahiru, Fusta Azupogo
BACKGROUND: Stunting and wasting are key public health problems in Ghana that are significantly linked with mortality and morbidity risk among children. However, information on their associated factors using nationally representative data is scanty in Ghana. This study investigated the influence of Infant and Young Child Feeding (IYCF) indicators, socio-demographic and economic related factors, and water and sanitation on stunting and wasting, using nationally representative data in Ghana...
2024: PloS One
https://read.qxmd.com/read/38546863/-evaluation-of-the-role-of-an-advanced-practice-dietitian-in-the-intensive-care-unit
#10
JOURNAL ARTICLE
Gioia Vinci, Reto Stocker
BACKGROUND: In Swiss intensive care units (ICUs), nutritional management is hardly or not at all supported or supervised by dietitians. Nutritional management in the ICU is mainly performed by ICU nursing staff and intensive care specialists. In 2022, the role of an advanced practice dietitian (APD) was newly defined, created, and implemented in a Swiss ICU as part of a pilot project. In contrast to other countries, APDs are still scarce in Switzerland. Evaluation of the APD role is essential to further define the position and adapt it to needs...
March 28, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://read.qxmd.com/read/38546309/vitamin-c-and-d-deficiency-in-urban-america-a-case-report
#11
JOURNAL ARTICLE
Alyssa A Lombardi, Maura Sammon, Kraftin E Schreyer
INTRODUCTION: Scurvy is caused by vitamin C deficiency and manifests with a variety of symptoms including generalized fatigue, apathy, anemia, myalgias, easy bruising, and poor wound healing. It is generally thought of as a disease of the past, especially in developed countries. However, vitamin C deficiency still occurs, especially in patients with lack of access to fruits and vegetables. Other micronutrient deficiencies, including vitamin D deficiency, are also prevalent and can cause a multitude of signs and symptoms including osteomalacia, muscle weakness, and increased risk of many chronic illnesses...
February 2024: Clinical Practice and Cases in Emergency Medicine
https://read.qxmd.com/read/38545856/relationship-between-educational-level-and-survival-of-patients-with-cancer-a-multicentre-cohort-study
#12
JOURNAL ARTICLE
Xiao-Yue Liu, Xi Zhang, Guo-Tian Ruan, Xin Zheng, Yue Chen, Xiao-Wei Zhang, Tong Liu, Yi-Zhong Ge, Han-Ping Shi
BACKGROUND: Although socioeconomic factors are important determinants of population mortality, the effect of educational level on the survival of patients with cancer in China is unclear. This study aimed to assess whether educational level is associated with the prognosis of patients with cancer and to explore the mediators of this association. METHODS: This multicentre cohort study included 18,251 patients diagnosed with cancer between May 2013 and December 2018...
April 2024: Cancer Medicine
https://read.qxmd.com/read/38545729/risk-factors-for-treatment-failure-in-multidrug-resistant-tuberculosis-in-tunisia-an-analytic-study
#13
JOURNAL ARTICLE
Fatma Tritar, Soumaya Ben Saad, Mariem Ferchichi, Amani Ben Mansour, Azza Slim, Othman Neffati, Hedia Bellili, Leila Slim, Hafaoua Daghfous
INTRODUCTION-AIM: The emergence of multidrug resistant tuberculosis (MDR-TB) is a threat to global public health. The aim of our study was to determine risk factors for treatment failure in MDR-TB. METHODS: Retrospective study conducted between January 2000 and March 2019 including patients with MDR-TB. Characteristics of patients with therapeutic failure were compared to cured ones. Logistic regression analysis was used to identify risk factors for treatment failure...
January 5, 2024: La Tunisie Médicale
https://read.qxmd.com/read/38545312/the-evaluation-of-the-effectiveness-of-a-health-promotion-training-on-breast-cancer-survivors
#14
JOURNAL ARTICLE
Bahar Kefeli Çol, Gülnihal Tufan, Dilek Kiliç
BACKGROUND: Increased early diagnosis and improved treatment options have decreased the mortality rate of breast cancer and increased the survival rate. Healthy lifestyle behaviors are very important in breast cancer survivors as they reduce mortality and morbidity rates, cancer recurrence frequency, and side effects of treatment and improve health. This study was conducted to evaluate the effectiveness of a health promotion training intervention in breast cancer survival. MATERIALS AND METHODS: The study is a quasi-experimental, pre-test-post-test and single-group study...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38544933/preparation-structural-characterization-biological-activity-and-nutritional-applications-of-oligosaccharides
#15
REVIEW
Ya-Jing Chen, Xin Sui, Yue Wang, Zhi-Hui Zhao, Tao-Hong Han, Yi-Jun Liu, Jia-Ning Zhang, Ping Zhou, Ke Yang, Zhi-Hong Ye
Oligosaccharides are low-molecular-weight carbohydrates between monosaccharides and polysaccharides. They can be extracted directly from natural products by physicochemical methods or obtained by chemical synthesis or enzymatic reaction. Oligosaccharides have important physicochemical and physiological properties. Their research and production involve many disciplines such as medicine, chemical industry, and biology. Functional oligosaccharides, as an excellent functional food base, can be used as dietary fibrer and prebiotics to enrich the diet; improve the microecology of the gut; exert antitumour, anti-inflammatory, antioxidant, and lipid-lowering properties...
June 30, 2024: Food chemistry: X
https://read.qxmd.com/read/38544925/multidimensional-deprivations-and-associated-factors-among-older-adults-in-urban-geographies-of-nigeria-implications-for-poor-health-outcomes-in-later-life
#16
JOURNAL ARTICLE
Jacob Wale Mobolaji
Objectives: Many urban-dwelling older Nigerians are multidimensionally deprived and are unable to meet their daily financial, nutritional, and healthcare needs. This has implications for their health outcomes, yet it has been under-researched. This study assessed the multidimensional deprivation index (MDI) of urban-dwelling older Nigerians and the associated factors. Methods: The study analysed a weighted sample of 5,225 older persons aged ≥60 years from Nigeria's Demographic and Health Survey, 2018...
2024: International Journal of Public Health
https://read.qxmd.com/read/38543013/unveiling-the-chemical-composition-bioactive-profile-and-antioxidant-capacity-of-dried-egyptian-jew-s-mallow-stems-as-a-promising-anticancer-agent
#17
JOURNAL ARTICLE
Marwa Rashad Ali, Huda Hassan Ibrahim, Aziza Ali Salah-Eldin
Phytochemicals from waste materials generated by agricultural and industrial processes have become globally significant due to their accessibility and potential effectiveness with few side effects. These compounds have essential implications in both medicine and the economy. Therefore, a quantitative analysis of the phytochemical profile, sugar types, and water-soluble vitamins of dried Corchorus olitorius L."DJMS" extract (dried Jew's mallow stem) was carried out with HPLC. In addition, the chemical composition, TPC, chlorophyll a and b, beta-carotene, and antioxidant effect using DPPH were investigated...
March 20, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38542818/nutritional-management-of-athletes-with-type-1-diabetes-a-narrative-review
#18
REVIEW
Massimiliano Cavallo, Michelantonio De Fano, Luisa Barana, Ivan Dozzani, Eleonora Bianchini, Marialucia Pellegrino, Linda Cisternino, Sara Migliarelli, Cecilia Giulietti, Roberto Pippi, Carmine Giuseppe Fanelli
Type 1 diabetes mellitus (T1DM) represents a complex clinical challenge for health systems. The autoimmune destruction of pancreatic beta cells leads to a complete lack of insulin production, exposing people to a lifelong risk of acute (DKA, coma) and chronic complications (macro and microvascular). Physical activity (PA) has widely demonstrated its efficacy in helping diabetes treatment. Nutritional management of people living with T1DM is particularly difficult. Balancing macronutrients, their effects on glycemic control, and insulin treatment represents a complex clinical challenge for the diabetologist...
March 21, 2024: Nutrients
https://read.qxmd.com/read/38542808/effects-of-ethanol-concentrations-on-primary-structural-and-bioactive-characteristics-of-dendrobium-officinale-polysaccharides
#19
JOURNAL ARTICLE
Juan Yu, Yan Long, Jinyue Chi, Keyao Dai, Xiaoyu Jia, Haiyu Ji
Ethanol fractional precipitation can initially separate polysaccharides according to the structure, which exhibits strong correlation with the biological activities. This study aimed to investigate the impact of varying ethanol concentrations on the structural characteristics, and the antitumor and antioxidant activities of polysaccharides derived from Dendrobium officinale through ethanol fractional precipitation, as well as their internal relationships. The polysaccharides acquired by absolute alcohol additions at a final liquor-ethanol volume ratio of 1:1, 1:2, and 1:4 were named DOP-1, DOP-2, and DOP-4, and the supernatant was named DOP-S...
March 20, 2024: Nutrients
https://read.qxmd.com/read/38542785/higher-level-steatosis-is-associated-with-a-greater-decrease-in-metabolic-dysfunction-associated-steatoic-liver-disease-after-eight-weeks-of-a-very-low-calorie-ketogenic-diet-vlckd-in-subjects-affected-by-overweight-and-obesity
#20
JOURNAL ARTICLE
Annamaria Sila, Sara De Nucci, Caterina Bonfiglio, Vincenza Di Stasi, Nicole Cerabino, Martina Di Chito, Roberta Rinaldi, Paola Cantalice, Endrit Shahini, Vito Giannuzzi, Pasqua Letizia Pesole, Sergio Coletta, Nicoletta Maria Tutino, Giuseppina Piazzolla, Raffaele Cozzolongo, Gianluigi Giannelli, Giovanni De Pergola
The most common form of chronic liver disease, recently defined as MASLD, is strongly linked to obesity and metabolic syndrome. Lifestyle changes are part of MASLD prevention. The very low-calorie ketogenic diet (VLCKD) is a useful option for treating MASLD and reducing liver steatosis in patients with obesity. We assessed whether a greater degree of steatosis could have a positive or negative impact on how well 8 weeks of using the VLCKD improve steatosis and fibrosis in a patient population of overweight and obese individuals...
March 18, 2024: Nutrients
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