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J Tayierjiang, N Waresijiang, H Wang
Objective: To evaluate the clinical results of the patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar had been treated by one stage posterior surgical procedure to debriment of lesion and titian mesh bone fusion with internal fixation by pedicle screw system. Method: From May 2008 to March 2014, there were total 30 patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar in Department of Orthopaedics, the People's Hospital of Xinjiang Uygur Autonoumy Region...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Małgorzata Pietrusińska, Aneta Pająk, Paweł Górski, Piotr Kuna, Janusz Szemraj, Agnieszka Goździńska-Nielepkowicz, Tadeusz Pietras
INTRODUCTION: The asthma- and chronic obstructive pulmonary disease (COPD)-related morbidity has been increasing during the recent years. Both asthma and COPD are diseases of inflammatory etiology. The increasing interest in the pathomechanisms involved in the development of obstructive pulmonary diseases seems to be fully justified. Recent research has attempted to determine the associations of microRNA with the pathogenesis of pulmonary diseases. AIM: To assess the expression of microRNA in the blood sera of patients diagnosed with bronchial asthma and chronic obstructive pulmonary disease in comparison with healthy subjects...
August 2016: Postȩpy Dermatologii i Alergologii
Emily Milne
Student success is facilitated by strong bonds between families and schools, including a shared sense of purpose and mutual trust. However, for Indigenous peoples these relationships are often broken, undermined by the legacy of residential schooling and assimilative educational practices. Drawing on interviews with 50 Indigenous (mainly Haudenosaunee, Anishinaabe, and Métis) and non-Indigenous parents and educators, this paper examines the ways in which issues of class and race shape interactions between teachers and Indigenous parents...
August 2016: Canadian Review of Sociology, Revue Canadienne de Sociologie
Sang-Il Ahn, Ji-Soo Kim, Gyo-Jeong Gu, Hyeon-Myeong Shin, Ah-Yeon Kim, Hyun-Jin Shim, Yeon Joo Kim, Kwang Oh Koh, Joo Yang Mang, Dae Young Kim, Hyung-Sun Youn
Toll-like receptor 4 (TLR4) recognizes lipopolysaccharide (LPS) and triggers the activation of myeloid differention factor 88 (MyD88) and the Toll/interleukin-1 receptor domain-containing adapter, inducing interferon-β (TRIF)-dependent major downstream signaling pathways. To evaluate the therapeutic potential of 1-[5-methoxy-2-(2-nitrovinyl)phenyl]pyrrolidine (MNP), previously synthesized in our laboratory, its effect on signal transduction via the TLR signaling pathways was examined. Here, we investigated whether MNP modulates the TLR4 signaling pathways and which anti-inflammatory target in TLR4 signaling is regulated by MNP...
October 2016: Archiv der Pharmazie
J Z Tan, E M Nie, C Y Zhang, R Jiang
OBJECTIVE: To investigate the effect of zinc ion on the expression of osteoblastic proteins. METHODS: Mice osteoblasts MC3T3-E1 cells were subcultured. Inflammatory environment model was established by tumor necrosis factor α(TNF-α)at a concentration of 10 mg/L. According to different concentration of Zn(2+), the cells were divided into TNF-α group, control group, group A(TNF-α+10(-4) mol/L Zn(2+)), group B(TNF-α+10(-5) mol/L Zn(2+)), group C(TNF-α+10(-6) mol/L Zn(2+))...
August 2016: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
Marie-Claire Lévesque, Natalie Le Sage, Simon Berthelot, Valérie Boucher, Éric Mercier, Marcel Émond
UNLABELLED: Objectif Notre objectif primaire est de mesurer l'incidence d'HPI selon quatre définitions différentes retrouvées dans la littérature. Notre principal objectif secondaire est d'évaluer l'impact de la présence d'instabilité hémodynamique avant l'intubation sur l'incidence d'HPI. Le deuxième objectif secondaire consiste à déterminer l'incidence de l'HPI en fonction de l'intervalle de temps durant lequel la première hypotension survient. Méthode Une cohorte prospective a été constituée par les patients intubés en salle de réanimation à l'hôpital de l'Enfant-Jésus entre le 28/06/2011 et le 12/07/2012...
September 2016: CJEM
Aker Fügen, Sayman Elif, Gümrükçü Gülistan, Doğan Meryem, Gürleyik Günay
Myofibroblastoma (MFB) is a benign tumor of the mammary stroma with predominant myofibroblastic differention. The cytologic reports of MFB are very few in the available literature. From the cytodiagnostic point of view about 21 cases of MFB with cytological evaluation by fine-needle aspiration cytology (FNAC) have been encountered in the English-language literature: A 35-year-old woman presented with lump in the left breast. FNAC showed mild degree of pleomorphism with occasional groups with fibrous stroma and tumoral cells...
July 26, 2016: Diagnostic Cytopathology
L Xu, L N Nwosu, J J Burston, P J Millns, D R Sagar, P I Mapp, P Meesawatsom, L Li, A J Bennett, D A Walsh, V Chapman
OBJECTIVE: Nerve growth factor (NGF) has a pivotal role in peripheral hyperalgesia and inflammation; anti-NGF antibodies attenuate pain responses in inflammatory pain models, and in people with osteoarthritis (OA) or low back pain. The aim of this study was to characterise the peripheral mechanisms contributing to the analgesic effects of anti-NGF antibody treatment in an established model of joint pain, which mimics key clinical features of OA. DESIGN: Effects of preventative vs therapeutic treatment with an anti-NGF antibody (monoclonal antibody 911: muMab 911 (10 mg/kg, s...
September 2016: Osteoarthritis and Cartilage
Sean Waite, Nicole Denier
This study presents novel evidence on the relationship between sexual orientation and self-employment. Using data from the 2001 and 2006 Census of Canada and the 2011 Canadian National Household Survey, we explore the propensity for self-employment among same- and opposite-sex couples. We examine the demographic, human capital, and family characteristics of coupled gay men and lesbians relative to their coupled heterosexual counterparts to offer potential mechanisms generating differences in rates of self-employment...
May 2016: Canadian Review of Sociology, Revue Canadienne de Sociologie
Masamitsu Eitoku, Narufumi Suganuma, Hidenori Kiyosawa
In vitro differentiation systems of mouse embryonic stem cells (ESCs) are widely used as tools for studies of cell differentiation, organogenesis, and regenerative medicine. We have studied the regulation of neuron-specific imprinting genes, Ube3a and its antisense transcripts (Ube3a ATS), using in vitro neuronal differentiation of F1 hybrid ESCs. Each different non-adherent plate used for embryoid body (EB) formation during differentiation is associated with different costs; notably, plates coated with 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer are more expensive than untreated polystyrene plates...
April 8, 2016: Cytotechnology
Sara Vienberg, Julian Geiger, Søren Madsen, Louise T Dalgaard
MicroRNAs (miRNAs) have within the past decade emerged as key regulators of metabolic homeostasis. Major tissues in intermediary metabolism important during development of the metabolic syndrome, such as β-cells, liver, skeletal and heart muscle as well as adipose tissue have all been shown to be affected by miRNAs. In the pancreatic β-cell a number of miRNAs are important in maintaining the balance between differentiation and proliferation (miR-200 and miR-29 families) and insulin exocytosis in the differentiated state is controlled by miR-7, miR-375 and miR-335...
March 24, 2016: Acta Physiologica
Yi Cui, Jin Han, Zhifeng Xiao, Tong Chen, Bin Wang, Bing Chen, Sumei Liu, Sufang Han, Yongxiang Fang, Jianshu Wei, Xiujie Wang, Xu Ma, Jianwu Dai
Increasing evidence suggests that three dimensional (3-D) cell cultures are an improvement over traditional two dimensional (2-D) cell cultures. Current researches have extensively focused on the study of utilizing biomaterial-based 3-D culture systems to study and direct stem-cell fate both in vitro and in vivo. Here in our study, we screened the differential expression patterns of miRNAs between 2-D cultured and 3-D cultured NPCs using microarray analysis. Among these differentially expressed miRNAs, miR-20 was found to increase during differentiation of NPCs...
2016: Scientific Reports
Isabelle Laurin, Danielle Guay, Michel Fournier, Nathalie Bigras, Anabel Solis
OBJECTIVES: Describe the preschool education of children in educational services. Study the effects of components of preschool educational service attendance on the development of kindergarten children, based on income. METHOD: A sample of 1,184 children was extracted from a survey frame that included Montréal children assessed in the 2012 Québec Survey of Child Development in Kindergarten (2012 QSCDK). Data collected from the parents of these children allowed us to document the following components of educational service attendance (independent variables): longitudinal profile of the service used; age at entry; duration; average weekly attendance; and cumulative time...
2015: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
S Toujani, F Daoud, Z Aydi, L Baili, B Ben Dhaou, F Boussema
OBJECTIFS: La maladie de Still de l'adulte (MSA) est une affection inflammatoire multisystémique d'étiologie inconnue caractérisée par une atteinte articulaire, une fièvre souvent hectique, une éruption fugace et des atteintes viscérales multiples. Au cours de cette affection systémique, l'atteinte rénale semble rare et polymorphe. Ce type d'atteinte est plus volontiers associé aux arthropathies sévères et à l'amylose de type AA. Des observations de néphropathies tubulo-interstitielles, membrano-polifératives ou mésangiales ont été rapportés...
December 2015: Annales de Cardiologie et D'angéiologie
F Saada, S Talbi, F Atrouz, S Ouanoughi
OBJECTIFS: Le lien entre hypertension artérielle (HTA) et maladie rénale en général, fût établit par Richard Bright en 1837. L'hypertension artérielle est particulièrement fréquente dans les néphropathies glomérulaires primitives et cette fréquence dépend d'une part de la nature histologique de la lésion et d'autre part du débit de la filtration glomérulaire. l'objectif principal de notre étude est de déterminer la fréquence de l'hypertension artérielle chez des patients présentant des néphropathies glomérulaires primitives et d'en préciser le mécanisme physiopathologique selon les différentes lésions anatomopathologiques...
December 2015: Annales de Cardiologie et D'angéiologie
M Najjar, H Jebali, R Kheder, M Khaddar, L Raïs, L Ben Fatma, W Smaoui, M Krid, F Ben Moussa, S Beji, K Zouaghi
OBJECTIFS: Au cours du lupus érythémateux systémique (LES), l'hypertension artérielle (HTA) est une manifestation fréquente de mécanisme multifactoriel. On se propose de déterminer le profil anatomo-clinique de l'HTA chez les patients ayant une néphropathie lupique (NL). MéTHODES: Il s'agit d'une étude rétrospective portant sur 42 patients suivis pour LES colligés sur une période de 7 ans (2007-2015). Nous avons étudié leurs caractéristiques cliniques, biologiques, histologiques et évolutives...
December 2015: Annales de Cardiologie et D'angéiologie
L Azouaou, A Belalbes, S Benssouna, L Bezzi, A Bellout, A Benoui, M Arab, N Raaf, W Missoum, M Cherifi, T Rayane
OBJECTIFS: La régulation de la tension artérielle est très difficile chez les patients hémodialysés. La correction de l'HTA en hémodialyse se fait par la méthode du poids sec. L'erreur d'estimation du poids sec chez les hémodialysés chroniques affecte leur morbi-mortalité. L'objectif de notre étude est de comparer les résultats de l'estimation « subjective » du poids sec par la clinique avec les résultats, de l'impédancemétrie, de l'échographie de la veine cave inférieure et du dosage du BNP, en vue de déterminer les facteurs de risque d'erreur d'estimation clinique du poids sec...
December 2015: Annales de Cardiologie et D'angéiologie
L Manamani, M Ait Athmane
OBJECTIFS: Décrire la présentation clinique, électrique et angiographique du syndrome coronarien aigu chez la femme. Comparer les résultats selon les deux sexes. MéTHODES: Étude prospective à double visée, descriptive et analytique, étalée sur une année. À propos de 160 cas de femmes admises pour SCA au niveau CHU Ibn Sina d'Annaba, comparées à 390 hommes hospitalisés également pour SCA durant la même période. Tous les patients ont bénéficié d'un interrrogatoire, d'un examen clinique, d'un ECG, d'un bilan biologique (troponine, fonction rénale, bilan lipidique…), d'une échocardiographie Doppler, et selon les indications, d'une coronarographie)...
December 2015: Annales de Cardiologie et D'angéiologie
S Ali-Guechi, A Ait-Kaci, S Boughandjioua, N Boukhris, A Chelghoum
OBJECTIFS: Le but de cette enquête est de déterminer la prévalence du surpoids et de l'obésité dans différentes catégories sociales, d'évaluer leur impact physique et psychique et de rechercher les facteurs de risque pouvant influencer leur survenue. MéTHODES: Enquête transversale descriptive réalisée en 3 mois concernant 130 sujets adultes issus de différentes catégories sociales : étudiants en médecine (n=30), médecins (n=30), malades (n=40) et 5 familles de 30 personnes habitant dans un quartier donné...
December 2015: Annales de Cardiologie et D'angéiologie
A Mahnane, M Abdoun, S Bouaoud, Z Zaidi, M Hamdi-Cherif, N Lafi
OBJECTIFS: Déterminer la fréquence de la mortalité hospitalière par les maladies cardiovasculaires, dont principalement l'hypertension artérielle (HTA). Évaluer les principales complications de l'HTA dans les causes de décès comme l'accident vasculaire cérébral. Étudier le profil épidémiologique des décès par maladies cardiovasculaires et l'HTA. MéTHODES: Il s'agit d'une étude épidémiologique descriptive, sur les décès hospitaliers par les maladies de l'appareil circulatoire et cardiovasculaire enregistrés au niveau du CHU de Sétif sur une période de neuf ans de 2006 à 2014...
December 2015: Annales de Cardiologie et D'angéiologie
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