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https://www.readbyqxmd.com/read/29144022/collagen-a-review-on-its-sources-and-potential-cosmetic-applications
#1
REVIEW
María Isabela Avila Rodríguez, Laura G Rodríguez Barroso, Mirna Lorena Sánchez
Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. This molecule is one of the most abundant in many of the living organisms due to its connective role in biological structures. Due to its abundance, strength and its directly proportional relation with skin aging, collagen has gained great interest in the cosmetic industry. It has been established that the collagen fibers are damaged with the pass of time, losing thickness and strength which has been strongly related with skin aging phenomena [Colágeno para todo...
November 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29143124/the-effect-of-inhibition-on-stimulus-specific-adaptation-in-the-inferior-colliculus
#2
Yaneri A Ayala, Manuel S Malmierca
The inferior colliculus is a center of convergence for inhibitory and excitatory synaptic inputs that may be activated simultaneously by sound stimulation. Stimulus repetition may generate response habituation by changing the efficacy of neuron's synaptic inputs. Specialized IC neurons reduce their response to repetitive tones, but restore their firing when a different and infrequent tone occurs, a phenomenon known as stimulus specific adaptation. Here, using the microiontophoresis technique, we determined the role of GABAA-, GABAB-, and glycinergic receptors in stimulus-specific adaptation (SSA)...
November 15, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29141853/the-effects-of-resistance-exercise-on-biomarkers-of-breast-cancer-prognosis-a-pooled-analysis-of-three-randomized-trials
#3
Kerri Winters-Stone, Lisa J Wood, Sydnee Stoyles, Nathan Dieckmann
BACKGROUND: Using a secondary data analysis from randomized controlled trials comparing one year of resistance exercise (N=109) to a placebo control condition (N=106) in postmenopausal, post-treatment breast cancer survivors, we investigated the influence of resistance training and changes in body composition on markers associated with cancer progression. METHODS: Measures included serum levels of insulin, IGF-1, IGFBP1-3, leptin, serum amyloid A (SAA), adiponectin, C-reactive protein (CRP), IL-1β, TNF-α, IL-6, and IL-8 and body composition (total, lean and fat mass in kg) by DXA at baseline, 6, and 12-months...
November 15, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29137402/bdnf-trkb-signaling-mediates-the-anorectic-action-of-estradiol-in-the-nucleus-tractus-solitarius
#4
Ling Shen, David Q H Wang, Meifeng Xu, Stephen C Woods, Min Liu
Although compelling evidence indicates that estradiol (E2) acts in the nucleus tractus solitarius (NTS) to reduce food intake, the underlying mechanisms are largely unknown. We now report that estrogen's anorectic action occurs through enhancing the strength of brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase (TrkB) signaling in the NTS. Intra-4th-ventricular administration of a low dose of BDNF reduced food intake to a greater extent in ovariectomized (OVX) rats cyclically treated with E2 than in vehicle-treated OVX rats, implying that cyclic E2 replacement increases BDNF's satiating potency...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29135222/engineering-the-mechanical-properties-of-polymer-networks-with-precise-doping-of-primary-defects
#5
Doreen Chan, Yichuan Ding, Reinhold Dauskardt, Eric A Appel
Polymer networks are extensively utilized across numerous applications ranging from commodity super-absorbent polymers and coatings to high performance microelectronics and biomaterials. For many applications, desirable properties are known, however, achieving them has been challenging. Additionally, the accurate prediction of elastic modulus has been a longstanding difficulty due to the presence of loops. By tuning the pre-polymer formulation through precise doping of monomers, specific primary network defects can be programmed into an elastomeric scaffold, without alteration of their resulting chemistry...
November 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29133398/analysis-of-high-resolution-3d-intrachromosomal-interactions-aided-by-bayesian-network-modeling
#6
Xizhe Zhang, Sergio Branciamore, Grigoriy Gogoshin, Andrei S Rodin, Arthur D Riggs
Long-range intrachromosomal interactions play an important role in 3D chromosome structure and function, but our understanding of how various factors contribute to the strength of these interactions remains poor. In this study we used a recently developed analysis framework for Bayesian network (BN) modeling to analyze publicly available datasets for intrachromosomal interactions. We investigated how 106 variables affect the pairwise interactions of over 10 million 5-kb DNA segments in the B-lymphocyte cell line GB12878...
November 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29132622/know-thy-ehealth-user-development-of-biopsychosocial-personas-from-a-study-of-older-adults-with-heart-failure
#7
Richard J Holden, Anand Kulanthaivel, Saptarshi Purkayastha, Kathryn M Goggins, Sunil Kripalani
BACKGROUND: Personas are a canonical user-centered design method increasingly used in health informatics research. Personas-empirically-derived user archetypes-can be used by eHealth designers to gain a robust understanding of their target end users such as patients. OBJECTIVE: To develop biopsychosocial personas of older patients with heart failure using quantitative analysis of survey data. METHOD: Data were collected using standardized surveys and medical record abstraction from 32 older adults with heart failure recently hospitalized for acute heart failure exacerbation...
December 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29129759/dampening-of-the-bone-formation-response-following-repeat-dosing-with-sclerostin-antibody-in-mice-is-associated-with-up-regulation-of-wnt-antagonists
#8
Gill Holdsworth, Kevin Greenslade, Joby Jose, Zofia Stencel, Hishani Kirby, Adrian Moore, Hua Zhu Ke, Martyn K Robinson
Administration of antibodies to sclerostin (Scl-Ab) has been shown to increase bone mass, bone mineral density (BMD) and bone strength by increasing bone formation and decreasing bone resorption in both animal studies and human clinical trials. In these studies, the magnitude and rate of increase in bone formation markers is attenuated upon repeat dosing with Scl-Ab despite a continuous and progressive increase in BMD. Here, we investigated whether the attenuation in the bone formation response following repeated administration of Scl-Ab was associated with increased expression of secreted antagonists of Wnt signalling and determined how the circulating marker of bone formation, P1NP, responded to single, or multiple doses, of Scl-Ab four days post-dosing...
November 9, 2017: Bone
https://www.readbyqxmd.com/read/29128437/participatory-action-research-opens-doors-mentoring-indigenous-researchers-to-improve-midwifery-in-urban-australia
#9
Sophie D Hickey, Sarah-Jade Maidment, Kayla M Heinemann, Yvette L Roe, Sue V Kildea
PROBLEM: There is increasing demand for capacity building among the Aboriginal and Torres Strait Islander (Indigenous) maternal and infant health workforce to improve health outcomes for mothers and babies; yet few studies describe the steps taken to mentor novice Indigenous researchers to contribute to creating a quality evidence-base in this space. BACKGROUND: The Indigenous Birthing in an Urban Setting study is a partnership project aimed at improving maternity services for Indigenous families in South East Queensland...
November 8, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29127601/interpreting-adaptation-to-concurrent-compared-with-single-mode-exercise-training-some-methodological-considerations
#10
REVIEW
Jackson J Fyfe, Jeremy P Loenneke
Incorporating both endurance and resistance training into an exercise regime is termed concurrent training. While there is evidence that concurrent training can attenuate resistance training-induced improvements in maximal strength and muscle hypertrophy, research findings are often equivocal, with some suggesting short-term concurrent training may instead further enhance muscle hypertrophy versus resistance training alone. These observations have questioned the validity of the purported 'interference effect' on muscle hypertrophy with concurrent versus single-mode resistance training...
November 10, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29126270/neural-plasticity-with-age-unilateral-maximal-strength-training-augments-efferent-neural-drive-to-the-contralateral-limb-in-older-adults
#11
Tiril Tøien, Runar Unhjem, Thomas Storehaug Øren, Ann Charlotte Gjertsen Kvellestad, Jan Hoff, Eivind Wang
Efferent neural drive during strong muscle contractions is attenuated with age, even after lifelong strength training. However, it is unknown if this deterioration may impede contralateral neural plasticity, and limit the clinical value of unilateral strength training. We assessed muscle force-generating capacity, evoked potentials recordings (V-wave and H-reflex normalized to M-wave; V/M-ratio and H/M-ratio) and voluntary activation (VA) in the plantar flexors of the contralateral limb following unilateral maximal strength training (MST) with the dominant limb for three weeks (9 sessions)...
November 4, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29123629/effect-of-low-level-laser-therapy-and-strength-training-protocol-on-hand-grip-by-dynamometry
#12
Rafael Barbosa, Alexandre Marcolino, Vitor Souza, Guilherme Bertolino, Marisa Fonseca, Rinaldo Guirro
Introduction: The purpose of this study was to investigate the effect of low-level laser therapy (LLLT) - 660 nm and 904 nm - before grip strength protocol in healthy subjects. Methods: The study included 45 healthy volunteers with an average age of 22.7 (±1.4) years, subdivided into the following groups, control group: grip strength training associated with placebo LLLT; 660 nm group: LLLT (660 nm, 20 J/cm(2), power of 30 mW, and beam area of 0.06 cm(2), continuous, energy 1.2 J, and exposure time 40 seconds per point) before grip strength training and 904 nm group: LLLT (904 nm, 10 J/cm(2), peak power of 70 W and 0...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29123628/evaluation-of-different-types-of-lasers-in-surface-conditioning-of-porcelains-a-review-article
#13
REVIEW
Amirhossin Mirhashemi, Nastaran Sharifi, Mohammad Moharrami, Nasim Chiniforush
To achieve proper bond strength for porcelains, adequate surface roughness is essential, which is traditionally gained by sandblasting or acid etching with hydrofluoric (HF) acid. Nowadays with the development of laser systems, serious efforts were made to apply this new instrument for surface etching of porcelains due to easy usage, safety, and more efficiency. There are different kinds of lasers and porcelains, so choosing the ones which will be good match for each other is crucial. Besides that, changing the irradiation setting can be beneficial as well...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29121506/what-factors-determine-the-preferred-gait-transition-speed-in-humans-a-review-of-the-triggering-mechanisms
#14
Stacey M Kung, Philip W Fink, Stephen J Legg, Ajmol Ali, Sarah P Shultz
Human locomotion is a fundamental skill that is required for daily living, yet it is not completely known how human gait is regulated in a manner that seems so effortless. Gait transitions have been analyzed to gain insight into the control mechanisms of human locomotion since there is a known change that occurs as the speed of locomotion changes. Specifically, as gait speed changes, there is a spontaneous transition between walking and running that occurs at a particular speed. Despite the growing body of research on the determinants of this preferred transition speed and thus the triggering mechanisms of human gait transitions, a clear consensus regarding the control mechanisms of gait is still lacking...
November 6, 2017: Human Movement Science
https://www.readbyqxmd.com/read/29120378/clinic-design-as-placebo-using-design-to-promote-healing-and-support-treatments
#15
Jonas Rehn, Kai Schuster
Analogously to the medical placebo effect, people seem to anticipate the quality of treatments based on external stimuli. In order to gain insights on the effect the built environment can have on a person's judgments and behavior with a particular focus on health related issues, a quantitative survey (N = 851) with four groups before and after the renovation of a rehabilitation clinic has been conducted. In line with an overall modernization of the clinic, the entrance, the lobby, and some patient rooms have been changed...
November 9, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/29119872/adapting-operational-research-training-to-the-rwandan-context-the-intermediate-operational-research-training-programme
#16
Jackline Odhiambo, Cheryl L Amoroso, Peter Barebwanuwe, Christine Warugaba, Bethany L Hedt-Gauthier
BACKGROUND: Promoting national health research agendas in low- and middle-income countries (LMICs) requires adequate numbers of individuals with skills to initiate and conduct research. Recently, non-governmental organizations (NGOs) have joined research capacity building efforts to increase research leadership by LMIC nationals. Partners In Health, an international NGO operating in Rwanda, implemented its first Intermediate Operational Research Training (IORT) course to cultivate Rwandan research talent and generate evidence to improve health care delivery...
2017: Global Health Action
https://www.readbyqxmd.com/read/29117586/stable-long-term-operation-of-an-upflow-anammox-sludge-bed-reactor-at-mainstream-conditions
#17
Clara Reino, María Eugenia Suárez-Ojeda, Julio Pérez, Julián Carrera
The efforts for implementing the anammox process at mainstream conditions with high nitrogen removal rates have gained much attention in the race for achieving an energy-positive urban wastewater treatment plant. Here, the successful and stable long-term operation of an Upflow Anammox Sludge Bed (UAnSB) reactor treating a low-strength synthetic influent amended with ammonium and nitrite for 420 days, and a nitrite-amended pre-treated real urban wastewater for 110 days at temperatures as low as 11 °C is presented...
October 30, 2017: Water Research
https://www.readbyqxmd.com/read/29117353/quantifying-overdiagnosis-in-cancer-screening-a-systematic-review-to-evaluate-the-methodology
#18
Theodora M Ripping, Kevin Ten Haaf, André L M Verbeek, Nicolien T van Ravesteyn, Mireille J M Broeders
Background: Overdiagnosis is the main harm of cancer screening programs but is difficult to quantify. This review aims to evaluate existing approaches to estimate the magnitude of overdiagnosis in cancer screening in order to gain insight into the strengths and limitations of these approaches and to provide researchers with guidance to obtain reliable estimates of overdiagnosis in cancer screening. Methods: A systematic review was done of primary research studies in PubMed that were published before January 1, 2016, and quantified overdiagnosis in breast cancer screening...
October 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29116213/the-performance-and-archaeal-community-shifts-in-a-modified-anaerobic-baffled-reactor-treating-sweet-potato-starch-wastewater-at-ambient-temperatures
#19
Shengjun Xu, Cancan Jiang, Shuanglong Ma, Shanghua Wu, Zhihui Bai, Guoqiang Zhuang, Xuliang Zhuang
A conventional anaerobic baffled reactors (ABRs) treating high strength sweet potato starch wastewater at ambient temperatures resulted in acidification and bad performances. After modification, the acidification was remitted and COD removal efficiencies reached 92.73% at high temperatures and were maintained at 71.19% at low temperatures. Moreover, as much as 1.014 ± 0.056 L CH4/L/d were collected at Stage III. The q-PCR results revealed that the largest methanogen populations emerged at Stage III as well, which was 5...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29114531/effects-of-a-short-term-detraining-period-on-muscle-functionality-and-cognition-of-strength-trained-older-women-a-preliminary-report
#20
Hélio José Coelho, Bruno Rodrigues, Ivan de Oliveira Gonçalves, Marco Carlos Uchida
The present study aimed to investigate the impact of a 1-month detraining composed by Christmas and New Year's Day in the functional and cognitive parameters of 12 older women who had previously participated in 22-week moderate intensity strength training program (ST; n=6) or remained performing their regular habits of life during all study period, without engaging in physical exercise programs (CG; n=6). Transfer capacity (i.e., Timed Up and Go [TUG]) and executive function (i.e., TUG with a cognitive task) were increased in the ST group after the intervention...
October 2017: Journal of Exercise Rehabilitation
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