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https://www.readbyqxmd.com/read/29116842/what-can-we-do-or-change-to-encourage-people-to-seek-out-preexposure-prophylaxis
#1
Lisa A Eaton
No abstract text is available yet for this article.
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29076941/newly-acquired-infection-with-multidrug-resistant-hiv-1-in-a-patient-adherent-to-preexposure-prophylaxis
#2
Martin Markowitz, Howard Grossman, Peter L Anderson, Robert Grant, Monica Gandhi, Howard Horng, Hiroshi Mohri
No abstract text is available yet for this article.
December 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29071519/preexposure-prophylaxis-of-hiv-infection-the-role-of-clinical-practices-in-ending-the-hiv-epidemic
#3
REVIEW
Iryna B Zablotska, Catherine C O'Connor
PURPOSE OF REVIEW: The aim of this study is to summarise the recent evidence from high-income settings about providers' ability to deliver on the UNAIDS goal of at least three million people at substantial risk of HIV infection with PrEP by 2020, including awareness and knowledge about PrEP, willingness to prescribe PrEP, current levels of prescribing and service delivery models and issues. RECENT FINDINGS: Awareness about PrEP among health providers is growing, but at different pace depending on provider type...
October 25, 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29059077/the-microbiome-and-hiv-prevention-strategies-in-women
#4
Salim S Abdool Karim, Jo-Ann S Passmore, Cheryl Baxter
PURPOSE OF REVIEW: HIV prevention approaches that women can use and control are a priority. Results from topical and oral preexposure prophylaxis (PrEP) HIV prevention trials have produced inconsistent results in women. One of the main behavioural factors impacting effectiveness of PrEP has been suboptimal adherence. In this review, we examine biological factors that modulate topical PrEP efficacy, with particular focus on the vaginal microbiome. RECENT FINDINGS: Genital inflammation is an independent risk factor for HIV acquisition in women...
October 20, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29048955/integrating-hiv-preexposure-prophylaxis-prep-into-routine-preventive-health-care-to-avoid-exacerbating-disparities
#5
Sarah K Calabrese, Douglas S Krakower, Kenneth H Mayer
More than 3 decades since its emergence in the United States, HIV continues to spread and disproportionately affect socially marginalized groups. Preexposure prophylaxis (PrEP), a highly effective prevention strategy federally approved since 2012, could fundamentally alter the course of the epidemic. However, PrEP's potential has not been fully realized, in part because health care providers have been slow to adopt PrEP in clinical practice and have been selective in their discussion of PrEP with patients. This nonstandardized approach has constrained PrEP access...
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29020235/redefining-hiv-preexposure-prophylaxis-failures
#6
Julia L Marcus, Leo B Hurley, Dong Phuong Nguyen, Michael J Silverberg, Jonathan E Volk
No abstract text is available yet for this article.
July 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020194/comparison-of-measures-of-adherence-to-hiv-preexposure-prophylaxis-among-adolescent-and-young-men-who-have-sex-with-men-in-the-united-states
#7
Catherine A Koss, Sybil G Hosek, Peter Bacchetti, Peter L Anderson, Albert Y Liu, Howard Horng, Leslie Z Benet, Karen Kuncze, Alexander Louie, Parya Saberi, Craig M Wilson, Monica Gandhi
Background: Young men who have sex with men (MSM) are disproportionately impacted by HIV. Preexposure prophylaxis (PrEP) could reduce HIV acquisition among youth, but sub-optimal adherence threatens effectiveness. Optimal metrics of PrEP adherence among adolescents have not been defined. Methods: The ATN 110 and 113 studies provided daily oral PrEP with tenofovir (TFV) disoproxil fumarate/emtricitabine over 48 weeks to a diverse population of MSM (15-22 years). Self-reported adherence was assessed and PrEP drug concentrations measured from hair and dried blood spot (DBS) samples; 23% of participants received Wisepill electronic monitoring devices...
August 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28991887/changes-in-kidney-function-associated-with-daily-tenofovir-disoproxil-fumarate-emtricitabine-for-hiv-preexposure-prophylaxis-use-in-the-united-states-demonstration-project
#8
Eric C Tang, Eric Vittinghoff, Peter L Anderson, Stephanie E Cohen, Susanne Doblecki-Lewis, Oliver Bacon, Megan E Coleman, Wairimu Chege, Susan P Buchbinder, Michael A Kolber, Richard Elion, Michael Shlipak, Albert Y Liu
BACKGROUND: HIV preexposure prophylaxis (PrEP) using daily oral tenofovir-disoproxil-fumarate/emtricitabine (TDF/FTC) is effective for preventing HIV acquisition, but concerns remain about its potential kidney toxicity. This study examined kidney function in individuals using PrEP in real-world clinical settings. SETTING: Demonstration project in two sexually transmitted infection clinics and a community health center. METHODS: We evaluated kidney function among men who have sex with men and transgender women taking TDF/FTC PrEP for up to 48 weeks...
October 4, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28910270/updated-dosing-instructions-for-immune-globulin-human-gamastan-s-d-for-hepatitis-a-virus-prophylaxis
#9
Noele P Nelson
GamaSTAN S/D (Grifols Therapeutics, Inc., Research Triangle Park, North Carolina) is a sterile, preservative-free solution of immune globulin (IG) for intramuscular administration and is used for prophylaxis against disease caused by infection with hepatitis A, measles, varicella, and rubella viruses (1). GamaSTAN S/D is the only IG product approved by the Food and Drug Administration for hepatitis A virus (HAV) prophylaxis. In July 2017, GamaSTAN S/D prescribing information was updated with changes to the dosing instructions for hepatitis A preexposure and postexposure prophylaxis indications...
September 15, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28906283/preexposure-prophylaxis-a-cautionary-tale
#10
Aimee A Desrosiers, Afsoon D Roberts, Gary L Simon
No abstract text is available yet for this article.
September 24, 2017: AIDS
https://www.readbyqxmd.com/read/28902677/disparities-in-awareness-of-hiv-postexposure-and-preexposure-prophylaxis-among-notified-partners-of-hiv-positive-individuals-new-york-city-2015-2017
#11
Kavita Misra, Chi-Chi Udeagu
BACKGROUND: Named sex- or needle-sharing partners of HIV-positive individuals are a priority prevention population due to their known HIV exposure. Understanding postexposure and preexposure prophylaxis (PEP and PrEP) awareness and use among them is important for successful interventions. METHODS: Data from notified partners of HIV-positive individuals (New York City, May 2015-April 2017) were analyzed to describe PEP/PrEP awareness, provider discussion, and use by sociodemographic and risk characteristics...
October 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28902562/preexposure-prophylaxis-adapting-hiv-prevention-models-to-achieve-worldwide-access
#12
Stewart Landers, Farzana Kapadia
No abstract text is available yet for this article.
October 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28902545/the-complex-road-ahead-for-preexposure-prophylaxis-a-primary-care-physician-perspective
#13
Richard E Greene
No abstract text is available yet for this article.
October 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28876325/modernizing-field-services-for-human-immunodeficiency-virus-and-sexually-transmitted-infections-in-the-united-states
#14
Matthew R Golden, David A Katz, Julia C Dombrowski
Public health field services for sexually transmitted infections (STIs) have not adequately evolved to address the expanding scale of the STI problem, its concentration among men who have sex with men, the emergence of new communication technologies and the availability of antiretroviral therapy as a cornerstone of human immunodeficiency virus (HIV) prevention. Field services need to modernize. Modernization should seek to expand field services objectives beyond sex partner STI testing and treatment to include: HIV testing of persons with bacterial STI and their partners, including efforts to promote frequent HIV/STI testing; increased condom access; linkage and relinkage to HIV care and promotion of viral suppression; preexposure prophylaxis promotion; linkage to long-acting contraception; and referral for health insurance...
October 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28876282/outcomes-of-preexposure-prophylaxis-referrals-from-public-sti-clinics-and-implications-for-the-preexposure-prophylaxis-continuum
#15
Ramona Bhatia, Laxmi Modali, Matthew Lowther, Nancy Glick, Margo Bell, Sarah Rowan, Kristin Keglovitz, John Schneider
BACKGROUND: Human immunodeficiency virus preexposure prophylaxis (PrEP) uptake remains low in high-risk populations. Sexually transmitted infection (STI) clinics reach PrEP-eligible persons and may be ideal settings to model PrEP implementation. METHODS: Consenting PrEP-eligible patients identified at Chicago Department of Public Health STI Clinics were actively referred to PrEP partner sites between June 1, 2015, and May 31, 2016. Outcomes included successful contact by a partner site, linkage to a partner site, and receipt of a PrEP prescription...
August 30, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28873128/safety-and-feasibility-of-antiretroviral-preexposure-prophylaxis-for-adolescent-men-who-have-sex-with-men-aged-15-to-17-years-in-the-united-states
#16
Sybil G Hosek, Raphael J Landovitz, Bill Kapogiannis, George K Siberry, Bret Rudy, Brandy Rutledge, Nancy Liu, D Robert Harris, Kathleen Mulligan, Gregory Zimet, Kenneth H Mayer, Peter Anderson, Jennifer J Kiser, Michelle Lally, Jennifer Brothers, Kelly Bojan, Jim Rooney, Craig M Wilson
Importance: Adolescents represent a key population for implementing preexposure prophylaxis (PrEP) interventions worldwide, yet tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for PrEP is only licensed for adults. Objective: To examine the safety of and adherence to PrEP along with changes in sexual risk behavior among adolescent men who have sex with men (MSM). Design, Setting, and Participants: Adolescent Medicine Trials Network for HIV/AIDS Interventions 113 (Project PrEPare) was a PrEP demonstration project that evaluated the safety, tolerability, and acceptability of TDF/FTC and patterns of use, rates of adherence, and patterns of sexual risk behavior among healthy young MSM aged 15 to 17 years...
September 5, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28873123/human-immunodeficiency-virus-preexposure-prophylaxis-for-adolescent-men-how-do-we-ensure-health-equity-for-at-risk-young-men
#17
Renata Arrington-Sanders
No abstract text is available yet for this article.
September 5, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28857826/preexposure-prophylaxis-for-men-who-have-sex-with-men-and-transgender-persons-in-early-adopting-countries-a-narrative-review
#18
E Hoornenborg, D S Krakower, M Prins, K H Mayer
No abstract text is available yet for this article.
August 28, 2017: AIDS
https://www.readbyqxmd.com/read/28853676/hiv-aids-conspiracy-beliefs-and-intention-to-adopt-preexposure-prophylaxis-among-black-men-who-have-sex-with-men-in-los-angeles
#19
Ronald A Brooks, Vincent C Allen, Rotrease Regan, Matt G Mutchler, Ramon Cervantes-Tadeo, Sung-Jae Lee
In the United States, black men who have sex with men (MSM) are the group most affected by the HIV/AIDS epidemic. Pre-exposure prophylaxis (PrEP) is an important new HIV prevention strategy that may help reduce new HIV infections among black MSM. This analysis examined the association between HIV/AIDS conspiracy beliefs and intentions to adopt PrEP among 224 black MSM. The likelihood of adopting PrEP was assessed and more than half (60%) of the study population indicated a high intention to adopt PrEP. HIV/AIDS genocidal and treatment-related conspiracies were assessed using scales previously validated with black MSM...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28834798/estimated-coverage-to-address-financial-barriers-to-hiv-preexposure-prophylaxis-among-persons-with-indications-for-its-use-united-states-2015
#20
Dawn K Smith, Michelle Van Handel, Rebecca Huggins
BACKGROUND: An estimated 1.2 million American adults engage in sexual and drug use behaviors that place them at significant risk of acquiring HIV infection. Engagement in health care for the provision of daily oral antiretroviral medication as preexposure prophylaxis (PrEP), when clinically indicated, could substantially reduce the number of new HIV infections in these persons. However, resources to cover the financial cost of PrEP care are anticipated barriers for many of the populations with high numbers of new HIV infections...
December 15, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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