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Functional reconstruction

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https://www.readbyqxmd.com/read/29166653/testing-the-applicability-of-a-benthic-foraminiferal-based-transfer-function-for-the-reconstruction-of-paleowater-depth-changes-in-rhodes-greece-during-the-early-pleistocene
#1
Yvonne Milker, Manuel F G Weinkauf, Jürgen Titschack, Andre Freiwald, Stefan Krüger, Frans J Jorissen, Gerhard Schmiedl
We present paleo-water depth reconstructions for the Pefka E section deposited on the island of Rhodes (Greece) during the early Pleistocene. For these reconstructions, a transfer function (TF) using modern benthic foraminifera surface samples from the Adriatic and Western Mediterranean Seas has been developed. The TF model gives an overall predictive accuracy of ~50 m over a water depth range of ~1200 m. Two separate TF models for shallower and deeper water depth ranges indicate a good predictive accuracy of 9 m for shallower water depths (0-200 m) but far less accuracy of 130 m for deeper water depths (200-1200 m) due to uneven sampling along the water depth gradient...
2017: PloS One
https://www.readbyqxmd.com/read/29166646/reconstruction-of-membrane-current-by-deconvolution-and-its-application-to-membrane-capacitance-measurements-in-cardiac-myocytes
#2
Matej Hoťka, Ivan Zahradník
Correct detection of membrane currents under whole-cell patch-clamp conditions is limited by the transfer function of a recording system. The low-pass output filter of a recording amplifier alters the time course of membrane current and causes errors in relevant descriptors. To solve these problems, we developed a practical procedure for reconstruction of the time course of membrane currents based on deconvolution of recorded currents in frequency domain. The procedure was tested on membrane capacitance estimates from current responses to step voltage pulses...
2017: PloS One
https://www.readbyqxmd.com/read/29166345/prepectoral-immediate-direct-to-implant-breast-reconstruction-with-anterior-alloderm-coverage
#3
Glyn Jones, Aran Yoo, Victor King, Brian Jao, Huaping Wang, Charalambos Rammos, Eric Elwood
BACKGROUND: Staged subpectoral expander-implant breast reconstruction is widely performed. Disruption of the pectoralis major origin and the frequent occurrence of animation deformity and functional discomfort associated with subpectoral reconstruction remain ongoing concerns. Prepectoral single-stage direct-to-implant reconstruction resolves many of these issues. In this study, the authors explored the rationale for prepectoral single-stage implant-based breast reconstruction with anterior AlloDerm coverage as an alternative to the staged approach...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29166342/important-considerations-for-performing-prepectoral-breast-reconstruction
#4
Hani Sbitany
Prepectoral breast reconstruction has emerged as an excellent technique for postmastectomy reconstruction, as it allows for full preservation of a patient's pectoralis major muscle and chest wall function. This reduces pain, eliminates animation deformity, and results in high patient satisfaction. Safely performed prepectoral breast reconstruction requires a careful patient selection process before committing to the procedure, taking into account comorbidities, radiation status, and oncologic criteria such as tumor location and breast cancer stage...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29166067/equilibrium-configurations-of-large-nanostructures-using-the-embedded-saturated-fragments-stochastic-density-functional-theory
#5
Eitam Arnon, Eran Rabani, Daniel Neuhauser, Roi Baer
An ab initio Langevin dynamics approach is developed based on stochastic density functional theory (sDFT) within a new embedded saturated fragment formalism, applicable to covalently bonded systems. The forces on the nuclei generated by sDFT contain a random component natural to Langevin dynamics, and its standard deviation is used to estimate the friction term on each atom by satisfying the fluctuation-dissipation relation. The overall approach scales linearly with the system size even if the density matrix is not local and is thus applicable to ordered as well as disordered extended systems...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29165902/multi-contrast-endomyocardial-imaging-by-single-channel-high-resolution-cross-polarization-optical-coherence-tomography
#6
Xinwen Yao, Yu Gan, Yuye Ling, Charles C Marboe, Christine P Hendon
A single-channel high-resolution cross-polarization (CP) optical coherence tomography (OCT) system is presented for multi-contrast imaging of human myocardium in one-shot measurement. The intensity contrast and functional contrasts, including the ratio between the cross- and co- polarization channels as well as the cumulative retardation, are reconstructed from the CP-OCT readout. By comparing the CP-OCT results with histological analysis, it is shown that the system can successfully delineate micro-structures in the myocardium and differentiate the fibrotic myocardium from normal or ablated myocardium based the functional contrasts provided by the CP-OCT system...
November 22, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29165438/our-experience-in-the-surgical-management-of-craniofacial-fibrous-dysplasia-what-has-changed-in-the-last-10-years
#7
V Valentini, A Cassoni, V Terenzi, M Della Monaca, M T Fadda, O Rajabtork Zadeh, I Raponi, A Anelli, G Iannetti
The mainstay of treatment of craniofacial dysplasia (CFD) remains surgery once clinical observation has been excluded. Nevertheless, disagreement remains about the type of surgical intervention (remodelling versus radical resection). The aim of this paper is to present our experience until 2013 comparing CFD management between 1980 and 2002 and between 2003 and 2013 and to propose our surgical algorithm. From January 2003 to December 2013, 41 new patients (18 males and 23 females) with histologically demonstrated CFD presented to our Department...
October 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29165433/management-of-free-flap-failure-in-head-and-neck-surgery
#8
C Copelli, K Tewfik, L Cassano, N Pederneschi, S Catanzaro, A Manfuso, R Cocchi
Free flap surgery is overall considered the gold standard in head and neck reconstruction, with a success rate of 95%. The management of a total flap necrosis and which solution, between a pedicled or a second free flap, is safer for a salvage procedure is still controversial. Object of this study is to describe the authors' management of total free flap loss in head and neck reconstruction and compare the choices and results to those reported in the literature. From January 2012 to January 2016, 149 consecutive free flaps were performed at the Maxillo- Facial Operative Unit of the Hospital Casa Sollievo della Sofferenza in San Giovanni Rotondo (Italy) for reconstruction of head and neck defects...
October 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29164368/3d-reconstruction-of-endoplasmic-reticulum-in-a-hydrocarbon-secreting-green-alga-botryococcus-braunii-race-b
#9
Reiko Suzuki, Ichiro Nishii, Shigeru Okada, Tetsuko Noguchi
Based on 3D sections through cells of Botryococcus braunii, the structure of three domains of endoplasmic reticulum, and their spatial and functional relationships to other organelles are clarified. Oil production by photosynthetic microalgae has attracted attention since these oils can be converted into renewable, carbon-neutral fuels. The green alga B. braunii accumulates large amounts of hydrocarbons, 30-50% of cell dry weight, in extracellular spaces rather than its cytoplasm. To advance the knowledge of hydrocarbon biosynthesis and transport pathways in this alga, we utilized transmission EM combined with rapid freezing and image reconstruction...
November 22, 2017: Planta
https://www.readbyqxmd.com/read/29164167/single-leg-hop-test-performance-and-isokinetic-knee-strength-after-anterior-cruciate-ligament-reconstruction-in-athletes
#10
Ted Sueyoshi, Akihiro Nakahata, Gen Emoto, Tomoki Yuasa
Background: Isokinetic strength and hop tests are commonly used to assess athletes' readiness to return to sport after knee surgery. Purpose/Hypothesis: The purpose of this study was to investigate the results of single-leg hop and isokinetic knee strength testing in athletes who underwent anterior cruciate ligament reconstruction (ACLR) upon returning to sport participation as well as to study the correlation between these 2 test batteries. The secondary purpose was to compare the test results by graft type (patellar tendon or hamstring)...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29164130/comparison-of-an-innovative-rehabilitation-combining-reduced-conventional-rehabilitation-with-balneotherapy-and-a-conventional-rehabilitation-after-anterior-cruciate-ligament-reconstruction-in-athletes
#11
Laetitia Peultier-Celli, Didier Mainard, Frank Wein, Nicolas Paris, Patrick Boisseau, Alexandre Ferry, René Gueguen, Isabelle Chary-Valckenaere, Jean Paysant, Philippe Perrin
Background: Instability of the knee, related to anterior cruciate ligament injury, is treated by surgical reconstruction. During recovery, a loss of proprioceptive input can have a significant impact. Few studies have evaluated the benefits of rehabilitation of the knee in aquatic environment on functional outcomes. Objective: This study aimed to compare an innovative rehabilitation protocol combining reduced conventional rehabilitation with aquatic rehabilitation, with a conventional rehabilitation, according to the National French Health Authority, in terms of kinetics, development of proprioceptive skills, and functional improvement of the knee...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29163399/minion-nanopore-sequencing-enables-correlation-between-resistome-phenotype-and-genotype-of-coliform-bacteria-in-municipal-sewage
#12
Yu Xia, An-Dong Li, Yu Deng, Xiao-Tao Jiang, Li-Guan Li, Tong Zhang
Wastewater treatment plants (WWTPs) functioned as the intersection between the human society and nature environment, are receiving increasingly more attention on risk assessment of the acquisition of environmental antibiotic resistance genes (ARGs) by pathogenetic populations during treatment. However, because of the general lack of robust resistome profiling methods, genotype, and resistance phenotype is still poorly correlated in human pathogens of sewage samples. Here we applied MinION sequencing to quantify the resistance genes of multiple antibiotic resistant (MAR) coliform bacteria, a common indicator for human enteric pathogens in sewage samples...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29163214/predictive-value-of-dynamic-cerebral-autoregulation-assessment-in-surgical-management-of-patients-with-high-grade-carotid-artery-stenosis
#13
Vladimir B Semenyutin, Gregory A Asaturyan, Anna A Nikiforova, Vugar A Aliev, Grigory K Panuntsev, Vadim B Iblyaminov, Alexander V Savello, Andreas Patzak
Dynamic cerebral autoregulation (DCA) capacity along with the degree of internal carotid artery (ICA) stenosis and characteristics of the plaque can also play an important role in selection of appropriate treatment strategy. This study aims to classify the patients with severe ICA stenosis according to preoperative state of DCA and to assess its dynamics after surgery. Thirty-five patients with severe ICA stenosis having different clinical type of disease underwent reconstructive surgery. DCA was assessed with transfer function analysis (TFA) by calculating phase shift (PS) between Mayer waves of blood flow velocity (BFV) and blood pressure (BP) before and after operation...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29163054/motor-deficits-and-cerebellar-atrophy-in-elovl5-knock-out-mice
#14
Eriola Hoxha, Rebecca M C Gabriele, Ilaria Balbo, Francesco Ravera, Linda Masante, Vanessa Zambelli, Cristian Albergo, Nico Mitro, Donatella Caruso, Eleonora Di Gregorio, Alfredo Brusco, Barbara Borroni, Filippo Tempia
Spino-Cerebellar-Ataxia type 38 (SCA38) is caused by missense mutations in the very long chain fatty acid elongase 5 gene, ELOVL5. The main clinical findings in this disease are ataxia, hyposmia and cerebellar atrophy. Mice in which Elovl5 has been knocked out represent a model of the loss of function hypothesis of SCA38. In agreement with this hypothesis, Elovl5 knock out mice reproduced the main symptoms of patients, motor deficits at the beam balance test and hyposmia. The cerebellar cortex of Elovl5 knock out mice showed a reduction of thickness of the molecular layer, already detectable at 6 months of age, confirmed at 12 and 18 months...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29162902/shear-stress-regulates-trpv4-channel-clustering-and-translocation-from-adherens-junctions-to-the-basal-membrane
#15
Sara Baratchi, Markus Knoerzer, Khashayar Khoshmanesh, Arnan Mitchell, Peter McIntyre
Localized Ca(2+) influx via TRPV4 on the surface of endothelial cells greatly influences endothelial adaptation to blood flow, but how mechanical stress from blood flow controls TRPV4 integration into this physiological function is not fully understood. Here, we studied the spatial organization of TRPV4 and its relationship to the adherens junction component β-catenin using single- and dual-color direct stochastic optical reconstruction microscopy (dSTORM). In non-stimulated endothelial cells, TRPV4 is clustered in small protein islands, as is β-catenin...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162784/quantitative-analysis-of-chronological-changes-in-the-volume-of-flaps-used-for-reconstruction-of-oral-cavity-defects
#16
Masashi Kimura, Ken Takada, Kenichiro Ishibashi, Hiroyuki Ohto, Akio Shibata, Hiroki Yamada, Shusuke Nishiwaki, Yoshiyuki Naganawa, Masahiro Umemura
Reconstruction of oral defects using flaps following resection of oral cancer has become a standard approach for restoration of oral function. The purpose of this study was to investigate chronological changes in the volume of such flaps used for reconstruction and the factors affecting flap volume. We performed a retrospective analysis of 17 patients who had undergone oral cancer resection and reconstruction with flaps. Measurements were performed using data from computed tomography, and the flaps were selected semi-automatically using a computer-operated region-of-interest system...
November 22, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/29162495/the-morphology-of-mouthparts-wings-and-genitalia-of-paleozoic-insect-families-protohymenidae-and-scytohymenidae-reveals-new-details-and-supposed-function
#17
Martina Pecharová, Jakub Prokop
Megasecoptera is an extinct group of insects with specialized rostrum-like mouthparts, which is a synapomorphy shared with all members of the Late Paleozoic Palaeodictyopterida, and markedly slender wings that are unable to flex backwards. Here we describe the close up morphology of Protohymenidae and Scytohymenidae and uncover new aspects of the endoskeleton (tentorium) of the head, structure of the mouthparts with discernable proximal part of stylets controlled by muscles, surface of compound eyes that consist of a hexagonal pattern of large facets, structure and microstructures on the wings and reconstruct male and female external genitalia using ESEM and light stereomicroscopy...
November 18, 2017: Arthropod Structure & Development
https://www.readbyqxmd.com/read/29162296/early-outcomes-of-vein-grafting-for-reconstruction-of-brachial-arterial-injuries-in-children
#18
Kristin Alves, Hillard Spencer, Carol E Barnewolt, Peter M Waters, Donald S Bae
PURPOSE: We postulated that, with microsurgical technique, vascular reconstruction with interpositional vein grafts in the pediatric population is safe and results in sustained vascular patency and excellent midterm outcomes. METHODS: Twenty children with brachial artery injuries were treated with interpositional vein grafting at a tertiary pediatric hospital from 1995 to 2013. Medical records were evaluated for demographic, clinical, and radiographic data. Ten patients were available for longer-term follow-up...
November 18, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29161295/cardiac-and-renal-dysfunction-is-associated-with-progressive-hearing-loss-in-patients-with-fabry-disease
#19
Maria Köping, Wafaa Shehata-Dieler, Mario Cebulla, Kristen Rak, Daniel Oder, Jonas Müntze, Peter Nordbeck, Christoph Wanner, Rudolf Hagen, Sebastian Schraven
BACKGROUND: Fabry disease (FD) is an X-linked recessive hereditary lysosomal storage disorder which results in the accumulation of globotriaosylceramid (Gb3) in tissues of kidney and heart as well as central and peripheral nervous system. Besides prominent renal and cardiac organ involvement, cochlear symptoms like high-frequency hearing loss and tinnitus are frequently found with yet no comprehensive data available in the literature. OBJECTIVE: To examine hearing loss in patients with FD depending on cardiac and renal function...
2017: PloS One
https://www.readbyqxmd.com/read/29160569/reconstruction-of-bladder-function-and-prevention-of-renal-deterioration-by-means-of-end-to-side-neurorrhaphy-in-rats-with-neurogenic-bladder
#20
Yun Long Li, Jian Jun Wen, Yi Bo Wen, Xiang Fei He, Jun Wei Wu, Yan Wei Li, Zhong Jiang Han, Jin Jin Feng, Shao Hua Yan, Shou Lin Li, John Pfa Heesakkers, Wan Sheng Gao, Jian Guo Wen
AIMS: To investigate the feasibility of restoring bladder function and prevention of renal deterioration by neurorrhaphy in rats with neurogenic bladder (NB). METHODS: Forty-two rats were assigned to the end-to-side nerve coaptation group (ECG, n = 16), no nerve coaptation group (NCG, n = 16), and control group (CG, n = 10). In the ECG, the left ventral root (VR) and dorsal root (DR) of L6 and S1 were transected, and the distal stump of L6VR was sutured to the lateral face of L4VR...
November 21, 2017: Neurourology and Urodynamics
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