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https://www.readbyqxmd.com/read/29245184/evaluation-of-the-use-of-novel-biomarkers-to-augment-antimicrobial-stewardship-program-activities
#1
Kayla R Stover, Rachel M Kenney, Travis S King, Alan E Gross
As antimicrobial stewardship increasingly receives worldwide attention for improving patient care by optimizing antimicrobial therapy, programs are evaluating new tools that may augment antimicrobial stewardship activities. Biomarkers are objective, accurate, and reproducible measures that provide information about medical conditions. A systematic literature search using PubMed/MEDLINE databases was performed to evaluate the use of novel biomarkers as additions to the antimicrobial stewardship armamentarium...
December 15, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/29245168/-school-entrance-examination-for-lateral-entrants-what-can-and-what-should-they-be-able-to-do-a-discussion-contribution-based-on-the-data-from-the-health-authority-frankfurt-am-main-2006-2016
#2
Maria Karathana, Bernhard Krackhardt, Manuela Schade, Ursel Heudorf
Question The medical investigation of school beginners is one of the essential tasks of the child and youth services of the health authorities. While in all federal states in Germany, the examination of all school beginners is legally clearly stipulated, the situation for "lateral entry", that is, children of school age, who are moving from a foreign country to a local German community and attending school there, is not clearly regulated in the respective school laws. This article presents the experiences of the lateral entry investigations in Frankfurt am Main...
December 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29245167/-are-we-really-as-happy-as-we-think-we-are-a-critical-examination-of-work-satisfaction-in-a-university-pediatric-hospital
#3
Andreas Hiemisch, Yve Stöbel-Richter, Gesine Grande, Elmar Brähler, Wieland Kiess
Goals Despite numerous reported deficits and an increasingly tense working environment in German hospitals, employees themselves often assess their job satisfaction as being high to very high. Hence, the board of directors does not have important arguments for sustainable improvement of working conditions. This discrepancy between working conditions and subjective satisfaction was the motivation for this work. Methods Data were acquired via an attitude survey at the University Hospital for Children and Adolescents Leipzig, with employees sub-divided into medical, nursing and administrative/technical staff...
December 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29244607/a-survey-of-risk-factors-for-digit-injuries-among-dogs-training-and-competing-in-agility-events
#4
Debra C Sellon, Katherine Martucci, John R Wenz, Denis J Marcellin-Little, Michelle Powers, Kimberley L Cullen
OBJECTIVE To identify potential risk factors for digit injuries in dogs training and competing in agility events. DESIGN Internet-based, retrospective, cross-sectional survey. ANIMALS 1,081 dogs training or competing in agility events. PROCEDURES Data were collected for eligible animals via retrospective surveys distributed electronically to handlers of dogs participating in agility-related activities. Variables evaluated included demographic (handlers) and signalment (dogs) information, physical characteristics of dogs, and injury characteristics...
January 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29243472/preliminary-ethical-appraisal-of-a-trial-what-s-it-all-about
#5
Helena Siipi
Preliminary ethical appraisal of medical trials is often based on the following four principles: respect for autonomy, beneficence, non-maleficence, and justice. Preliminary ethical appraisal should, however, not be understood solely as application of these four principles to practice. Ethical committees will inevitably interpret the principles and make decisions about their reciprocal importance in connection with each trial. Reasoning does not always proceed from above towards practical recommendations of action, but can instead also be based on a moral rule or practice relating to a certain action...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29243467/high-resolution-ct-of-the-lungs-indications-and-diagnosis
#6
Helena Lauri
High-resolution computed tomography (HRCT) is a method of examination which is more precise than chest 2-rat in the diagnosis and monitoring of diseases of the lung tissue and the airways. Modern CT equipment enables a volume HRCT scan covering the whole lung tissue. HRCT slices can also be constructed from contrast-enhanced CT scans of the chest of the whole body. HRCT of the lungs can be applied to the diagnosis of both acute and more chronic diffuse diseases of the lung tissue and the airways. The best-known indications for HRCT include idiopathic interstitial pneumonias, such as idiopathic pulmonary fibrosis...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29240347/genomic-data-into-everyday-work-of-a-medical-practitioner-digital-tools-for-decision-making
#7
Sakari Jokiranta, Kristina Hotakainen, Iiris Salonen, Pasi Pöllänen, Kai-Petri Hänninen, Jari Forsström, Ilkka Kunnamo
Recent technological development has enabled fast and cost-effective simultaneous analyses of several gene variants or sequence of even the whole genome. For medical practitioners this has created challenges although genomic information may be clinically useful in new applications such as finding out individual risk for diseases influenced by as many as 50,000 variable DNA regions or in detecting pharmacogenetic risks prior to prescribing a medicine. New digital tools have paved the way for utilization of genomic data via easy access and clear clinical interpretation for both doctor and patient...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29239850/small-bowel-capsule-endoscopy-may-we-delegate-it-to-nurses
#8
Johann Dreanic, Maximilien Barret, Marion Dhooge, Marianne Gaudric, Sarah Leblanc, Vered Abitbol, Frederic Prat, Stanislas Chaussade, Romain Coriat
AIM: Small bowel capsule endoscopy (CE) is a non-invasive and validated technique allowing the visualization of the small intestine mucosa. It generated more than 40,000 images per examination and induced a long median time of medical reading that may exceed 1 hour. In a transfer of skills' program, the CE reading might be transferred to nurses. We herein evaluate and present a feasibility study of the CE to nurses. METHODS: Nurses experienced in endoscopy were trained for small bowel CE reading, selection and interpretation of pathological images...
November 24, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/29239842/relative-rates-not-relative-risks-addressing-a-widespread-misinterpretation-of-hazard-ratios
#9
Rinku Sutradhar, Peter C Austin
The use of the Cox proportional hazards model is ubiquitous in modern medical research. Despite the widespread implementation of this model, the terminology and interpretation that is used to describe the estimate hazard ratio (HR) has become loose and, unfortunately, often incorrect. Although some journals offer guidelines that advise against reporting HRs as relative risks, these guidelines are frequently overlooked. Perhaps due to a lack of understanding, authors continue to interpret the resultant HR as a relative risk-such an interpretation is inappropriate and can be misleading...
November 7, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29239834/do-residency-selection-factors-predict-radiology-resident-performance
#10
Vikas Agarwal, Gregory M Bump, Matthew T Heller, Ling-Wan Chen, Barton F Branstetter, Nikhil B Amesur, Marion A Hughes
RATIONALE AND OBJECTIVES: The purpose of our study is to determine what information in medical student residency applications predicts radiology residency success as defined by objective clinical performance data. MATERIALS AND METHODS: We performed a retrospective cohort study of residents who entered our institution's residency program through the National Resident Matching Program as postgraduate year 2 residents and completed the program over the past 2 years...
November 24, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29239587/redefining-medical-care
#11
Lauren R Roth
President Donald J. Trump has said he will repeal the Affordable Care Act (ACA) and replace it with health savings accounts (HSAs). Conservatives have long preferred individual accounts to meet social welfare needs instead of more traditional entitlement programs. The types of "medical care" that can be reimbursed through an HSA are listed in section 213(d) of the Internal Revenue Code (Code) and include expenses "for the diagnosis, cure, mitigation, treatment, or prevention of disease, or for the purpose of affecting any structure or function of the body...
2017: Cornell Journal of Law and Public Policy
https://www.readbyqxmd.com/read/29238799/association-of-clinical-dermoscopic-and-histopathologic-findings-with-gene-expression-in-patients-with-balloon-cell-melanoma
#12
Ben J Friedman, Rebecca Stoner, Joya Sahu, Jason B Lee
Importance: Balloon cell melanoma is a rare subtype of melanoma that is underrecognized clinically and is challenging to diagnose on histologic studies. Objective: To further characterize the clinical, dermoscopic, and histopathologic features of balloon cell melanomas and their correlation to gene expression. Design, Setting, and Participants: Case series of 2 patients with balloon cell melanoma whose medical records were retrieved from the database of Thomas Jefferson University Dermatopathology Center in Philadelphia, Pennsylvania...
December 13, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29238601/clinicians-approaches-to-management-of-background-treatment-in-patients-with-sle-in-clinical-remission-results-of-an-international-observational-survey
#13
Pintip Ngamjanyaporn, Eoghan M McCarthy, Jamie C Sergeant, John Reynolds, Sarah Skeoch, Benjamin Parker, Ian N Bruce
Background: The definition of remission in systemic lupus erythematosus (SLE) remains unclear, especially how background treatment should be interpreted. Objective: To determine preferences of clinicians in treatment of patients in clinical remission from SLE and to assess how previous severity, duration of remission and serology influence changes in treatment. Methods: We undertook an internet-based survey of clinicians managing patients with SLE...
2017: Lupus Science & Medicine
https://www.readbyqxmd.com/read/29238478/exploring-the-challenges-of-the-iranian-parliament-about-passing-laws-for-resource-allocation-in-healthcare-a-qualitative-study
#14
Seyed Ramezan Mohsenpour, Mohammad Arab, Seyed Hasan Emami Razavi, Ali Akbari Sari
Background: Awareness about the process of law making and the factors that affect the legislative process have an important role in improving legislations that are approved by parliaments. Objective: This study aimed to explore and analyze the process of development and enactment of law in Iran's parliament, and factors that might affect the enactment of laws that are related to the allocation and distribution of health sector resources in Iran. Methods: In this case study, data were collected through review of literature and national documents, and experts' interviews...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29237786/commentary-waltzing-around-sacred-cows-on-the-way-to-the-future
#15
Stephen M Brecher
Our mostly manual, agar based clinical microbiology laboratory is slowly but steadily being re-defined by automation and innovation. Ironically, the oldest test, the Gram stain, is still manually read and interpreted by trained personnel. In this proof of concept study Smith et al. (https://doi.org/10.1128/JCM.01521-17) have used computer imaging with a deep convolutional neural network to examine and interpret Gram-stained slides from positive blood culture bottles. In light of the shortage of medical technologists/microbiologists and the need for results of positive blood culture bottles 24/7, this paper paves the way for the next innovations for the clinical microbiology laboratory of the future...
December 13, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29236882/narratives-of-family-members-on-the-suicide-of-older-adults-in-an-amazonian-metropolis
#16
André Luis Sales da Costa, Maximiliano Loiola Ponte de Souza
OBJECTIVE: To analyze the narratives of family members on the suicide of older adults in Manaus, State of Amazonas, Brazil. METHODS: This is a qualitative study of the narratives of eight older adults, who committed suicide in the period of 2001-2012. In the analytic-interpretative process, we have tried to perform the hermeneutic double exercise: to interpret the interpretation of narrators. We have used as theoretical references authors who have investigated suicide from the perspective of gender and its correlations with the sociofamiliar context and with mental disorders...
December 11, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29236710/the-burden-of-obesity-in-women-of-reproductive-age-and-in-pregnancy-in-a-middle-income-setting-a-population-based-study-from-jamaica
#17
Lovney Kanguru, Affette McCaw-Binns, Jacqueline Bell, Novie Yonger-Coleman, Rainford Wilks, Julia Hussein
INTRODUCTION: Obesity is rising globally and is associated with increased risk of adverse pregnancy outcomes. This study aims to investigate overweight and obesity and its consequences among Jamaican women of reproductive age, particularly development of diabetes, hypertension and the risk of maternal death. MATERIALS AND METHODS: A national lifestyle survey (2007/8) of 1371 women of reproductive age provided data on the prevalence of high BMI, associated risk factors and co-morbidities...
2017: PloS One
https://www.readbyqxmd.com/read/29232365/monitoring-compliance-with-standards-of-care-for-chronic-diseases-using-healthcare-administrative-databases-in-italy-strengths-and-limitations
#18
Rosa Gini, Martijn J Schuemie, Alessandro Pasqua, Emanuele Carlini, Francesco Profili, Iacopo Cricelli, Patrizio Dazzi, Valentina Barletta, Paolo Francesconi, Francesco Lapi, Andrea Donatini, Giulia Dal Co, Modesta Visca, Mariadonata Bellentani, Miriam Sturkenboom, Niek Klazinga
BACKGROUND: A recent comprehensive report on healthcare quality in Italy published by the Organization of Economic Co-operation and Development (OECD) recommended that regular monitoring of quality of primary care by means of compliance with standards of care for chronic diseases is performed. A previous ecological study demonstrated that compliance with standards of care could be reliably estimated on regional level using administrative databases. This study compares estimates based on administrative data with estimates based on GP records for the same persons, to understand whether ecological fallacy played a role in the results of the previous study...
2017: PloS One
https://www.readbyqxmd.com/read/29232260/high-alert-medication-stratification-tool-revised-an-exploratory-study-of-an-objective-standardized-medication-safety-tool
#19
Natalie C Washburn, Heather A Dossett, Andrew C Fritschle, Kerri E Degenkolb, Monica R Macik, Todd A Walroth
OBJECTIVE: To develop an objective tool designed to standardize the identification of high-alert medications (HAMs) according to patient safety risk. METHODS: Medications were evaluated using the High-Alert Medication Stratification Tool (HAMST). Tool revision occurred through assessing medications on an organization-approved HAM list and comparing scores with control medications not included on the list. Because of variations in HAMST interpretation by end users in interdisciplinary committees, a revision of the scoring tool was completed to create the High-Alert Medication Stratification Tool-Revised (HAMST-R), and the assessment was repeated...
December 12, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/29230712/sensitivity-of-the-medication-possession-ratio-to-modelling-decisions-in-large-claims-databases
#20
Margret V Bjarnadottir, David Czerwinski, Eberechukwu Onukwugha
OBJECTIVES: When preparing administrative medical and pharmacy claims data for analysis, decisions about data clean up and analytical approach need to be made. However, information about the effects of various modelling decisions on adherence measures such as the medication possession ratio (MPR) is limited. We address this gap with this study. METHODS: We utilized cross-sectional administrative claims data for commercially insured members filling at least two prescriptions for drugs within five classes of hypertension medication between 2008 and 2010...
December 11, 2017: PharmacoEconomics
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