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https://www.readbyqxmd.com/read/28807395/clinical-validation-of-pinopode-as-a-marker-of-endometrial-receptivity-a-randomized-controlled-trial
#1
Zhang Qiong, Hao Jie, Wang Yonggang, Xu Bin, Zhao Jing, Li Yanping
OBJECTIVE: To determine the clinical value of pinopodes in the human. DESIGN: Randomized controlled trial. SETTING: Academic fertility center. PATIENT(S): From December 2014 to December 2016, in a phase I trial, 363 patients were recruited in their first IVF cycles. In a phase II trial, 136 patients with at least two previous embryo implantation failures were recruited. INTERVENTION(S): In the phase I trial, in the midluteal phase, endometrial tissues were obtained for scanning electron microscopy, and their IVF treatment outcomes were followed up...
August 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28782146/cerebroplacental-ratio-in-reduced-fetal-movements-evidence-for-worsening-fetal-hypoxemia
#2
Julia Binder, Caitriona Monaghan, Baskaran Thilaganathan, José Morales-Roselló, Asma Khalil
OBJECTIVE: To investigate the fetal cerebroplacental ratio (CPR) in women presenting with reduced fetal movements (RFM). METHODS: This is a retrospective cohort study conducted over a 7-year period at a Fetal Medicine Unit at a tertiary referral centre. 4500 singleton pregnancies presenting with RFM after 36 weeks' gestation and 1527 control pregnancies at a similar gestation without RFM were analysed. Fetal biometry and Doppler parameters were recorded and converted into centiles and multiples of the median (MoM)...
August 7, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28746928/diagnostic-performance-of-cerebroplacental-ratio-thresholds-at-term-for-prediction-of-low-birthweight-and-adverse-intrapartum-and-neonatal-outcomes-in-a-term-low-risk-population
#3
Larissa N Bligh, Amal Al Solai, Ristan M Greer, Sailesh Kumar
OBJECTIVES: To investigate the screening performance and best threshold centile (5th vs. 10th) of the cerebroplacental ratio (CPR) in low-risk, term pregnancies to predict low birthweight and adverse intrapartum and neonatal outcomes in a term, low-risk population. METHODS: This was a blinded, prospective, cross-sectional study of low-risk singleton pregnancies at term. Women attended fortnightly from 36 weeks for CPR and estimated fetal weight assessment. Intrapartum and neonatal outcomes were recorded...
July 27, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28744986/complete-recovery-of-fulminant-peripartum-cardiomyopathy-on-mechanical-circulatory-support-combined-with-high-dose-bromocriptine-therapy
#4
Patrick Horn, Diyar Saeed, Payam Akhyari, Denise Hilfiker-Kleiner, Malte Kelm, Ralf Westenfeld
Peripartum cardiomyopathy (PPCM) is an idiopathic cardiomyopathy presenting with heart failure due to left ventricular systolic dysfunction towards the end of pregnancy or in the months following delivery, where no other cause of heart failure is found. We report a case of a woman with PPCM who developed a critical cardiogenic shock with repeated cardiopulmonary resuscitation. We show for the first time that mechanical circulatory support combined with high-dose bromocriptine therapy to suppress systemic prolactin levels may serve as an effective therapeutic option in patients with fulminant PPCM and cardiogenic shock...
July 25, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28743074/coronary-perfusion-pressure-and-compression-quality-in-maternal-cardiopulmonary-resuscitation-in-supine-and-left-lateral-tilt-positions-a-prospective-crossover-study-using-mannequins-and-swine-models
#5
Satoshi Dohi, Kiyotake Ichizuka, Ryu Matsuoka, Kohei Seo, Masaaki Nagatsuka, Akihiko Sekizawa
OBJECTIVE: The risk of maternal and fetal mortality is high if cardiopulmonary arrest occurs during pregnancy. To assess the best position for maternal cardiopulmonary resuscitation (CPR), a prospective randomized crossover study was undertaken, involving basic life support mannequin-based simulation (BLS-MS) and a swine model of pulseless electrical activity (an unstable cardiac state) incorporating a fetal mannequin (PEA-FM). STUDY DESIGN: The BLS-MS (performed by certified rescuers) served to evaluate the quality of chest compressions in 30° left lateral tilt (LLT) and supine positions...
July 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28738721/the-clinical-value-of-maternal-and-fetal-doppler-parameters-in-low-risk-postdates-pregnancies-%C3%A2-a-prospective-study
#6
Oshrit Lebovitz, Eran Barzilay, Shali Mazaki-Tovi, Itai Gat, Reuven Achiron, Yinon Gilboa
OBJECTIVE: To determine the clinical significance of maternal and fetal ultrasound Doppler flow indices in postdates pregnancies. METHODS: This prospective study comprised 120 low-risk pregnant women beyond 40 weeks of gestation. All participants underwent Doppler assessment including of fetal middle cerebral artery (MCA), umbilical and uterine arteries. Perinatal outcomes were recorded and evaluated for possible associations with Doppler flow values. Adverse perinatal outcomes were defined as umbilical cord arterial pH < 7...
July 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28719429/maternal-salvage-with-extracorporeal-life-support-lessons-learned-in-a-single-center
#7
Philippe Biderman, Uri Carmi, Eric Setton, Michael Fainblut, Oren Bachar, Sharon Einav
The American Heart Association scientific statement on cardiac arrest in pregnancy did not endorse extracorporeal life support for lack of cohort data. We studied all pregnancy and peripartum cases of extracorporeal life support in 1 medical center (n = 11), including collapse due to infection (n = 6, 55%), thromboembolism (n = 3, 27%), and cardiac disease (n = 2, 18%). Half of the cases (n = 5, 45%) involved extracorporeal cardiopulmonary resuscitation. Most mothers survived (n = 7, 64% [95% confidence interval, 32%-88%])...
July 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28715660/elevated-basal-progesterone-levels-are-associated-with-increased-preovulatory-progesterone-rise-but-not-with-higher-pregnancy-rates-in-icsi-cycles-with-gnrh-antagonists
#8
Mehmet Firat Mutlu, Mehmet Erdem, Ilknur Mutlu, Berk Bulut, Ahmet Erdem
OBJECTIVE: To ascertain the association between basal progesterone (P) levels and the occurrence of preovulatory progesterone rise (PPR) and clinical pregnancy rates (CPRs) in ICSI cycles with GnRH antagonists. STUDY DESIGN: Serum P levels of 464 patients were measured on day 2 and day of hCG of cycles. Cycles with basal P levels>1.6ng/mL were cancelled. All embryos were cryopreserved in cycles with P levels≥2ng/mL on the day of hCG. The primary outcome measures were the incidence of PPR (P>1...
June 29, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28708272/prognostic-accuracy-of-cerebroplacental-ratio-and-middle-cerebral-artery-doppler-for-adverse-perinatal-outcomes-a-systematic-review-and-meta-analysis
#9
REVIEW
Charlotte A Schreurs, Marjon A de Boer, Martijn W Heymans, Linda J Schoonmade, Patrick M M Bossuyt, Ben Willem J Mol, Christianne J M de Groot, Caroline J Bax
OBJECTIVE: Ultrasonographic assessment of the cerebroplacental ratio (CPR) and middle cerebral artery (MCA) Doppler is widely used as an additional method to umbilical artery (UA) Doppler to identify fetuses at risk of adverse perinatal outcomes. However, reported estimates of its accuracy vary considerably. We conducted a systematic review with meta-analysis of studies on the prognostic accuracy of CPR and MCA Doppler, and compared this to UA Doppler. METHODS: We queried PubMed, EMBASE, the Cochrane Library, and ClinicalTrials...
July 14, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28707059/a-prospective-cohort-study-on-the-prediction-of-fetal-distress-and-neonatal-status-with-arterial-and-venous-doppler-measurements-in-appropriately-grown-term-fetuses
#10
Ihsan Atabay, Semir Kose, Erkan Cagliyan, Bora Baysal, Ebru Yucesoy, Sabahattin Altunyurt
PURPOSE: To assess the predictive power of the cerebro-placental ratio (CPR) and the venous-arterial index (VAI) for the development of intrapartum fetal distress (FD) and neonatal intensive care unit (NICU) admission. METHODS: Fetal umbilical artery, middle cerebral artery and umbilical vein Doppler measurements were obtained before the active phase of labor in 311 singleton pregnancies at ≥37 weeks. A continuous electronic fetal monitorization was applied, and an umbilical cord blood sample was obtained for each participant...
July 13, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28698074/fertiloscopy-improves-in-vitro-fertilization-for-women-with-repeated-implantation-failure
#11
R Zhang, A Xu, Q Wang, L Zhang, L Zhu, S Zhao, W Xiong
OBJECTIVE: To assess the effects of fertiloscopy procedure on the outcomes of subsequent in vitro fertilization cycles in patients with repeated implantation failure (RIF). METHODS: A retrospective study was performed on 50 patients underwent fertiloscopy and 41 controls with RIF. Pelvic and intrauterine pathologies related to infertility, clinical pregnancy rate (CPR) and ongoing pregnancy rate (OPR) of subsequent IVF cycles were assessed. RESULTS: Twenty-six out of 50 patients (52%) had abnormal fertiloscopic findings...
July 8, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28670921/progesterone-progesterone-estradiol-and-art-outcomes-in-day-5-transfer-cycles
#12
Ritika Arora, Crystal Chan, Xiang Y Ye, Ellen M Greenblatt
The objective of this study was to assess the effects of elevated luteal-phase progesterone levels (PE) and high progesterone/estradiol ratio ('P/E2' ratio) on IVF outcomes, exclusively in GnRH-antagonist cycles with day-5 embryo transfer. PE was not found to have a significant effect on implantation or clinical pregnancy rate (CPR) (OR 0.56, 95% CI 0.25-1.25, p = .16). Elevated 'P/E2' ratio (≥0.55) on trigger day was associated with a poorer response to stimulation and lower clinical pregnancy rates (OR 0...
July 2, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28666794/measuring-contraceptive-prevalence-among-women-who-are-at-risk-of-pregnancy
#13
Madeleine Short Fabic, Stan Becker
OBJECTIVE(S): The contraceptive prevalence rate (CPR) is generally reported among in-union women ages 15-49. Here, union status and age serve as proxies for exposure to the risk of pregnancy. As a result of changing dynamics, age and union status proxies may be insufficient for determining the rate of contraceptive use among women at risk of pregnancy. Our objectives are to define a measure of contraceptive use among women at risk; to measure contraceptive use among such women; and to compare this rate with conventional CPR...
June 27, 2017: Contraception
https://www.readbyqxmd.com/read/28619771/revealed-versus-concealed-criteria-for-placental-insufficiency-in-an-unselected-obstetric-population-in-late-pregnancy-ratio37-randomised-controlled-trial-study-protocol
#14
Francesc Figueras, Eduard Gratacos, Marta Rial, Ilan Gull, Ladislav Krofta, Marek Lubusky, Rogelio Cruz-Martinez, Mónica Cruz-Lemini, Miguel Martinez-Rodriguez, Pamela Socias, Cristina Aleuanlli, Mauro C Parra Cordero
INTRODUCTION: Fetal growth restriction (FGR) affects 5%-10% of all pregnancies, contributing to 30%-50% of stillbirths. Unfortunately, growth restriction often is not detected antenatally. The last weeks of pregnancy are critical for preventing stillbirth among babies with FGR because there is a pronounced increase in stillbirths among growth-restricted fetuses after 37 weeks of pregnancy. Here we present a protocol (V.1, 23 May 2016) for the RATIO37 trial, which evaluates an integrated strategy for accurately selecting at-risk fetuses for delivery at term...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28618098/pre-labor-fetal-cardiac-function-and-its-relationship-with-intrapartum-fetal-compromise-and-neonatal-status-at-term
#15
Amal A Alsolai, Larissa N Bligh, Ristan M Greer, Sailesh Kumar
OBJECTIVES: To prospectively investigate the relationship between fetal cardiac function and Doppler parameters with intrapartum fetal compromise (IFC) in term appropriately grown fetuses prior to labour. Secondary outcomes were to correlate prenatal cardiac function with neonatal acid base status, intrapartum fetal heart rate abnormalities adverse neonatal outcomes. METHODS: This was a blinded, prospective, observational, cohort study, at the Mater Mother's Hospital, Brisbane, Australia...
June 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28605430/intravenous-retro-uterine-echographic-surveillance-of-the-foetus-during-surgical-thrombectomy-for-life-threatening-pulmonary-thromboembolism
#16
Shin Yajima, Shunsuke Saito, Koichi Toda, Yoshiki Sawa
Pulmonary thromboembolism is a life-threatening disease, particularly during pregnancy. We report a case of successful cardiopulmonary resuscitation followed by surgical thrombectomy in a 35-year-old woman at 28 weeks of gestation. Intracardiac echocardiography was percutaneously located behind the uterus, and greatly assisted monitoring of the foetal condition and haemodynamic status.
June 12, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28594099/cerebroplacental-ratio-thresholds-measured-within-two-weeks-of-birth-and-the-risk-of-cesarean-section-for-intrapartum-fetal-compromise-and-adverse-neonatal-outcome
#17
Larissa N Bligh, Amal A Alsolai, Ristan M Greer, Sailesh Kumar
OBJECTIVES: Prediction of intrapartum fetal compromise in uncomplicated, term pregnancies is a global obstetric challenge. Currently, no widely accepted screening test for this condition exists, although the cerebroplacental ratio (CPR) shows promise. We aimed to prospectively evaluate the screening performance of the CPR 10(th) centile for detection of Cesarean section for intrapartum fetal compromise (IFC) and composite adverse neonatal outcome (ANO) in low-risk women from 36 weeks and to determine the best CPR threshold from three previously described in the literature...
June 8, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28587619/contraceptive-practices-among-married-women-of-reproductive-age-in-bangladesh-a-review-of-the-evidence
#18
REVIEW
Fauzia Akhter Huda, Yolande Robertson, Sabiha Chowdhuri, Bidhan Krishna Sarker, Laura Reichenbach, Ratana Somrongthong
BACKGROUND: Bangladesh has experienced a sevenfold increase in its contraceptive prevalence rate (CPR) in less than forty years from 8% in 1975 to 62% in 2014. However, despite this progress, almost one-third of pregnancies are still unintended which may be attributed to unmet need for family planning and discontinuation and switching of methods after initiation of their use. METHODS: We conducted an extensive literature review on contraceptive use among married women of reproductive age (MWRA) in Bangladesh...
June 6, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28579707/barriers-to-contraceptive-uptake-among-women-of-reproductive-age-in-a-semi-urban-community-of-ekiti-state-southwest-nigeria
#19
Kabir A Durowade, Lukman O Omokanye, Olusegun E Elegbede, Stella Adetokunbo, Charles O Olomofe, Akinyosoye D Ajiboye, Makinde A Adeniyi, Taofik A Sanni
BACKGROUND: Globally, unplanned pregnancy and sexually transmitted infections (STIs) persist as a significant threat to women's reproductive health. In Nigeria, despite huge resources committed to family planning programs by stakeholders, contraceptive use has been very low. This study aimed at unraveling the barriers to the use of modern contraceptives among women of reproductive age (15-49 years) in Ise-Ekiti community, Ekiti State, Southwest Nigeria. METHODS: This study was a cross sectional study among women aged 15-49 years...
March 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28579408/pregnancy-outcome-of-in%C3%A2-vitro-fertilization-after-essure-and-laparoscopic-management-of-hydrosalpinx-a-systematic-review-and-meta-analysis
#20
REVIEW
Bin Xu, Qiong Zhang, Jing Zhao, Yonggang Wang, Dabao Xu, Yanping Li
OBJECTIVE: To assess and compare pregnancy outcomes in hydrosalpinx (HX) patients treated by Essure, laparoscopic salpingectomy, and proximal tubal occlusion (LPTO) before IVF. DESIGN: Systematic review and meta-analysis. SETTING: University-affiliated teaching hospital. PATIENT(S): Women undergoing Essure, laparoscopic salpingectomy, and LPTO for HX before IVF. INTERVENTION(S): The overall combined risk estimates were calculated by means of fixed- or random-effects models...
July 2017: Fertility and Sterility
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