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https://www.readbyqxmd.com/read/29217684/retrieval-demands-adaptively-change-striatal-old-new-signals-and-boost-subsequent-long-term-memory
#1
Nora A Herweg, Tobias Sommer, Nico Bunzeck
The striatum is a central part of the dopaminergic mesolimbic system and contributes both to the encoding and retrieval of long-term memories. In this regard, the co-occurrence of striatal novelty and retrieval success effects in independent studies underlines the structure's double duty and suggests dynamic contextual adaption. To test this hypothesis and further investigate the underlying mechanisms of encoding and retrieval dynamics, human subjects viewed pre-familiarized scene images intermixed with new scenes and classified them as indoor vs...
December 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29211500/correlates-of-tinder-use-and-risky-sexual-behaviors-in-young-adults
#2
Gilla K Shapiro, Ovidiu Tatar, Arielle Sutton, William Fisher, Anila Naz, Samara Perez, Zeev Rosberger
Tinder is a frequently used geosocial networking application that allows users to meet sexual partners in their geographical vicinity. Research examining Tinder use and its association with behavioral outcomes is scarce. The objectives of this study were to explore the correlates of Tinder use and risky sexual behaviors in young adults. Participants aged 18-26 were invited to complete an anonymous online questionnaire between January and May 2016. Measures included sociodemographic characteristics, Tinder use, health related behaviors, risky sexual behaviors, and sexual attitudes...
December 6, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29209184/dynamics-of-intersubject-brain-networks-during-anxious-anticipation
#3
Mahshid Najafi, Joshua Kinnison, Luiz Pessoa
How do large-scale brain networks reorganize during the waxing and waning of anxious anticipation? Here, threat was dynamically modulated during human functional MRI as two circles slowly meandered on the screen; if they touched, an unpleasant shock was delivered. We employed intersubject correlation analysis, which allowed the investigation of network-level functional connectivity across brains, and sought to determine how network connectivity changed during periods of approach (circles moving closer) and periods of retreat (circles moving apart)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29208422/support-vector-machine-based-classification-of-first-episode-drug-na%C3%A3-ve-schizophrenia-patients-and-healthy-controls-using-structural-mri
#4
Yuan Xiao, Zhihan Yan, Youjin Zhao, Bo Tao, Huaiqiang Sun, Fei Li, Li Yao, Wenjing Zhang, Shah Chandan, Jieke Liu, Qiyong Gong, John A Sweeney, Su Lui
Although regional brain deficits have been demonstrated in schizophrenia patients by structural MRI studies, one important question that remains largely unanswered is whether the complex and subtle deficits revealed by MRI could be used as objective biomarkers to discriminate patients from healthy controls individually. To address this question, a total of 326 right-handed participants were recruited, including 163 drug-naïve first-episode schizophrenia (FES) patients and 163 demographically matched healthy controls...
December 2, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29205574/different-pre-scanning-instructions-induce-distinct-psychological-and-resting-brain-states-during-functional-magnetic-resonance-imaging
#5
Toshikazu Kawagoe, Keiichi Onoda, Shuhei Yamaguchi
Resting-state functional magnetic resonance imaging (rs-fMRI) is widely used to investigate functional brain network connectivity during rest or when the subject is not performing an explicit task. In the standard procedure, subjects are instructed to "let your mind wander" or "think of nothing." While these instructions appear appropriate to induce a "resting-state," they could induce distinct psychological and physiological states during the scan. In this study, we investigated whether different instructions affect mental state and functional connectivity (FC) (i...
December 4, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29192157/linking-functional-connectivity-and-dynamic-properties-of-resting-state-networks
#6
Won Hee Lee, Sophia Frangou
Spontaneous brain activity is organized into resting-state networks (RSNs) involved in internally-guided, higher-order mental functions (default mode, central executive and salience networks) and externally-driven, specialized sensory and motor processing (auditory, visual and sensorimotor networks). RSNs are characterized by their functional connectivity in terms of within-network cohesion and between-network integration, and by their dynamic properties in terms of synchrony and metastability. We examined the relationship between functional connectivity and dynamic network features using fMRI data and an anatomically constrained Kuramoto model...
November 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29182372/modulation-of-working-memory-load-distinguishes-individuals-with-and-without-balance-impairments-following-mild-traumatic-brain-injury
#7
Elizabeth J Woytowicz, Chandler Sours, Rao P Gullapalli, Joseph Rosenberg, Kelly P Westlake
OBJECTIVES: Balance and gait deficits can persist after mild traumatic brain injury (TBI), yet an understanding of the underlying neural mechanism remains limited. The purpose of this study was to investigate differences in attention network modulation in patients with and without balance impairments 2-8 weeks following mild TBI. METHODS: Using functional magnetic resonance imaging, we compared activity and functional connectivity of cognitive brain regions of the default mode, central-executive and salience networks during a 2-back working memory task in participants with mild TBI and balance impairments (n = 7, age 47 ± 15 years) or no balance impairments (n = 7, age 47 ± 15 years)...
November 28, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29179629/spinal-cord-injury-disrupts-resting-state-networks-in-the-human-brain
#8
Ammar Hawasli, Jerrel Rutlin, Jarod L Roland, Rory Murphy, Sheng-Kwei Song, Eric Leuthardt, Joshua Shimony, Wilson Z Ray
Despite 253,000 spinal cord injury (SCI) patients in America, little is known about how SCI affects brain networks. Spinal magnetic resonance imaging (MRI) provides only structural information with no insight into functional connectivity. Resting-state functional MRI (RS-fMRI) quantifies network connectivity through the identification of resting-state networks (RSNs) and allows detection of functionally-relevant changes during disease. Given the robust network of spinal cord afferents to the brain, we hypothesized SCI produces meaningful changes in brain RSNs...
November 27, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29176684/acupuncture-analgesia-involves-modulation-of-pain-induced-gamma-oscillations-and-cortical-network-connectivity
#9
Michael Hauck, Sven Schröder, Gesa Meyer-Hamme, Jürgen Lorenz, Sunja Friedrichs, Guido Nolte, Christian Gerloff, Andreas K Engel
Recent studies support the view that cortical sensory, limbic and executive networks and the autonomic nervous system might interact in distinct manners under the influence of acupuncture to modulate pain. We performed a double-blind crossover design study to investigate subjective ratings, EEG and ECG following experimental laser pain under the influence of sham and verum acupuncture in 26 healthy volunteers. We analyzed neuronal oscillations and inter-regional coherence in the gamma band of 128-channel-EEG recordings as well as heart rate variability (HRV) on two experimental days...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29175464/salience-network-coupling-is-linked-to-both-tobacco-smoking-and-symptoms-of-attention-deficit-hyperactivity-disorder-adhd
#10
A C Janes, J M Gilman, B B Frederick, M Radoman, G Pachas, M Fava, A E Evins
INTRODUCTION: Attention deficit hyperactivity disorder (ADHD) symptoms, even those below diagnostic threshold, enhance the likelihood of nicotine dependence, suggesting a neurobiological link between disorders. Of particular interest is the salience network (SN), which mediates attention to salient internal/external stimuli to guide behavior and is anchored by the dorsal anterior cingulate cortex (dACC) and bilateral anterior insula (AI). Disrupted interactions between the SN and the default mode (DMN) and central executive networks (CEN) have been noted in both ADHD and nicotine dependence...
November 21, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29175032/convergent-and-divergent-functional-connectivity-patterns-in-patients-with-long-term-left-sided-and-right-sided-deafness
#11
Yanyang Zhang, Zhiqi Mao, Shiyu Feng, Wenxin Wang, Jun Zhang, Xinguang Yu
Cortical reorganization may be induced in long-term single-sided deafness (SD); however, the influence of the deafness side on the functional changes remains poorly understood. Here, we investigated whole-brain functional connectivity patterns in long-term SD patients. The normalized voxel-based functional connectivity strength (FCS) was determined using resting-state fMRI (rs-fMRI) in 17 left-sided deafness (LD) patients, 21 right-sided deafness (RD) patients and 21 healthy controls (HCs). Relative to the HCs, both the LD and RD patients exhibited a reduction in the FCS in the ipsilateral visual cortex...
November 22, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29169125/functional-connectivity-between-salience-default-mode-and-frontoparietal-networks-in-post-stroke-depression
#12
Vladislav Balaev, Ivan Orlov, Alexey Petrushevsky, Olga Martynova
BACKGROUND: Previous studies have demonstrated altered resting state functional connectivity (rsFC) in patients with post-stroke depression (PSD). It remains unclear whether rsFC is changed at the network level as was shown for major depressive disorder (MDD). To address this question, we investigated rsFC of resting sate networks (RSNs) in PSD. METHODS: Eleven subjects with PSD underwent fMRI scanning at rest before and after treatment. The severity of depression was assessed using the aphasic depression rating scale (ADRS)...
November 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29165901/influence-of-ventral-tegmental-area-input-on-cortico-subcortical-networks-underlying-action-control-and-decision-making
#13
Anja Richter, Oliver Gruber
It is argued that the mesolimbic system has a more general function in processing all salient events, including and extending beyond rewards. Saliency was defined as an event that is unexpected due to its frequency of occurrence and elicits an attentional-behavioral switch. Using functional magnetic resonance imaging (fMRI), signals were measured in response to the modulation of salience of rewarding and nonrewarding events during a reward-based decision making task, the so called desire-reason dilemma paradigm (DRD)...
November 22, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29164505/network-level-dysconnectivity-in-patients-with-nasopharyngeal-carcinoma-npc-early-post-radiotherapy-longitudinal-resting-state-fmri-study
#14
Yingwei Qiu, Zheng Guo, Lujun Han, Yadi Yang, Jing Li, Shiliang Liu, Xiaofei Lv
In this study, we seek to longitudinally investigate the network-level functional connectivity (FC) alternations and its association with irradiation dose and cognition changes in the early stage post radiotherapy (RT) in nasopharyngeal carcinoma (NPC) patients. We performed independent component analysis (ICA) of resting state blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) from 39 newly diagnosed NPC patients before receiving treatment (baseline), and 3 months post-RT. the default mode network (DMN), salience network (SN), and executive control network (ECN) were extracted with well-validated software (GIFT)...
November 21, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29161362/the-hierarchical-organization-of-the-default-dorsal-attention-and-salience-networks-in-adolescents-and-young-adults
#15
Yuan Zhou, Karl J Friston, Peter Zeidman, Jie Chen, Shu Li, Adeel Razi
An important characteristic of spontaneous brain activity is the anticorrelation between the core default network (cDN) and the dorsal attention network (DAN) and the salience network (SN). This anticorrelation may constitute a key aspect of functional anatomy and is implicated in several brain disorders. We used dynamic causal modeling to assess the hypothesis that a causal hierarchy underlies this anticorrelation structure, using resting-state fMRI of healthy adolescent and young adults (N = 404). Our analysis revealed an asymmetric effective connectivity, such that the regions in the SN and DAN exerted an inhibitory influence on the cDN regions; whereas the cDN exerted an excitatory influence on the SN and DAN regions...
November 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29159045/identifying-functional-network-changing-patterns-in-individuals-at-clinical-high-risk-for-psychosis-and-patients-with-early-illness-schizophrenia-a-group-ica-study
#16
Yuhui Du, Susanna L Fryer, Dongdong Lin, Jing Sui, Qingbao Yu, Jiayu Chen, Barbara Stuart, Rachel L Loewy, Vince D Calhoun, Daniel H Mathalon
Although individuals at clinical high risk (CHR) for psychosis exhibit a psychosis-risk syndrome involving attenuated forms of the positive symptoms typical of schizophrenia (SZ), it remains unclear whether their resting-state brain intrinsic functional networks (INs) show attenuated or qualitatively distinct patterns of functional dysconnectivity relative to SZ patients. Based on resting-state functional magnetic imaging data from 70 healthy controls (HCs), 53 CHR individuals (among which 41 subjects were antipsychotic medication-naive), and 58 early illness SZ (ESZ) patients (among which 53 patients took antipsychotic medication) within five years of illness onset, we estimated subject-specific INs using a novel group information guided independent component analysis (GIG-ICA) and investigated group differences in INs...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29154684/brain-functional-connectivity-in-headache-disorders-a-narrative-review-of-mri-investigations
#17
Catherine D Chong, Todd J Schwedt, Anders Hougaard
Resting-state functional magnetic resonance imaging (rs-fMRI) is used to interrogate the functional connectivity and network organization amongst brain regions. Functional connectivity is determined by measuring the extent of synchronization in the spontaneous fluctuations of blood oxygenation level dependent (BOLD) signal. Here, we review current rs-fMRI studies in headache disorders including migraine, trigeminal autonomic cephalalgias, and medication overuse headache. We discuss (1) brain network alterations that are shared amongst the different headache disorders and (2) network abnormalities distinct to each headache disorder...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29136310/brain-networks-of-the-imaginative-mind-dynamic-functional-connectivity-of-default-and-cognitive-control-networks-relates-to-openness-to-experience
#18
Roger E Beaty, Qunlin Chen, Alexander P Christensen, Jiang Qiu, Paul J Silvia, Daniel L Schacter
Imagination and creative cognition are often associated with the brain's default network (DN). Recent evidence has also linked cognitive control systems to performance on tasks involving imagination and creativity, with a growing number of studies reporting functional interactions between cognitive control and DN regions. We sought to extend the emerging literature on brain dynamics supporting imagination by examining individual differences in large-scale network connectivity in relation to Openness to Experience, a personality trait typified by imagination and creativity...
November 14, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29135273/-neuroscience-of-mental-flexibility
#19
Zoltán Janka
Mental flexibility enabling shifts from the usual prepotent behaviour to new strategies and solutions is a significant factor in the successful adaptation to the changing environment. Components of mental flexibility comprise attention, salience detection, inhibition, working memory and switch processes which can be measured by neurocognitive tests. Data derived from examinations by the methods of cognitive neuroscience can be compared to the features, observed under resting state and during task performance, of brain structures and functions...
November 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29131369/photobiomodulation-for-traumatic-brain-injury-and-stroke
#20
REVIEW
Michael R Hamblin
There is a notable lack of therapeutic alternatives for what is fast becoming a global epidemic of traumatic brain injury (TBI). Photobiomodulation (PBM) employs red or near-infrared (NIR) light (600-1100nm) to stimulate healing, protect tissue from dying, increase mitochondrial function, improve blood flow, and tissue oxygenation. PBM can also act to reduce swelling, increase antioxidants, decrease inflammation, protect against apoptosis, and modulate microglial activation state. All these mechanisms of action strongly suggest that PBM delivered to the head should be beneficial in cases of both acute and chronic TBI...
November 13, 2017: Journal of Neuroscience Research
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