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https://www.readbyqxmd.com/read/29141368/-long-term-efficacy-of-open-reduction-and-internal-fixation-versus-external-fixation-for-unstable-distal-radius-fractures-a-meta-analysis
#1
Z Yang, Z Z Yuan, J X Ma, X L Ma
Objective: To make a systematic assessment of the Long-term efficacy of open reduction and internal fixation versus external fixation for unstable distal radius fractures. Methods: A computer-based online search of PubMed, ScienceDirect, EMBASE, BIOSIS, Springer and Cochrane Library were performed. The randomized and controlled trials of open reduction and internal fixation versus external fixation for unstable distal radius fractures were collected. The included trials were screened out strictly based on the criterion of inclusion and exclusion...
November 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29141152/tm-values-and-unfolded-fraction-can-predict-aggregation-rates-for-gcsf-variant-formulations-but-not-under-predominantly-native-conditions
#2
Mathew J Robinson, Paul Matejtschuk, Adrian F Bristow, Paul A Dalby
Protein engineering and formulation optimisation strategies can be taken to minimise protein aggregation in the biopharmaceutical industry. Short-term stability measures such as the mid-point transition temperature (Tm) for global unfolding provide convenient surrogates for longer-term (eg 2-year) degradation kinetics, with which to optimise formulations on practical time-scales. While successful in some cases, their limitations have not been fully evaluated or understood. Tm values are known to correlate with chemical degradation kinetics for wild-type granulocyte colony stimulating factor (GCSF) at pH 4-5...
November 15, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29141133/hierarchical-assembly-of-dna-filaments-with-designer-elastic-properties
#3
Barbara Sacca, Wolfgang Pfeifer, Pascal Lill, Christos Gatsogiannis
The elastic features of protein filaments are encoded in their component units and in the way they are connected, thus defining a biunivocal relationship between the monomer and the result of its self-assembly. Using DNA origami approaches, we constructed a reconfigurable module, composed of two quasi-independent domains and four possible interfaces, capable of facial and lateral growing through specific recognition patterns. Whereas the flexibility of the intra-domains region can be regulated by switchable DNA motifs, the inter-domain interfaces feature mutually and self-complementary shapes, whose pairwise association leads to filaments of programmable periodicity and variable persistence length...
November 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/29141073/forces-of-tool-tissue-interaction-to-assess-surgical-skill-level
#4
Taku Sugiyama, Sanju Lama, Liu Shi Gan, Yaser Maddahi, Kourosh Zareinia, Garnette R Sutherland
Importance: The application of optimal forces between surgical instruments and tissue is fundamental to surgical performance and learning. To date, this force has not been measured clinically during the performance of microsurgery. Objectives: To establish a normative catalog of force profiles during the performance of surgery, to compare force variables among surgeons with different skill levels, and to evaluate whether such a force-based metric determines or differentiates skill level...
November 15, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29140995/process-strengths-determine-the-forms-of-the-relationship-between-plant-species-richness-and-primary-productivity
#5
Zhenhong Wang
The current rates of biodiversity loss have exceeded the rates observed during the earth's major extinction events, which spurs the studies of the ecological relationships between biodiversity and ecosystem functions, stability, and services to determine the consequences of biodiversity loss. Plant species richness-productivity relationship (SRPR) is crucial to the understanding of these relationships in plants. Most ecologists have reached a widespread consensus that the loss of plant diversity undoubtedly impairs ecosystem functions, and have proposed many processes to explain the SRPR...
2017: PloS One
https://www.readbyqxmd.com/read/29140959/comparison-of-continuous-proximal-versus-distal-adductor-canal-blocks-for-total-knee-arthroplasty-a-randomized-double-blind-noninferiority-trial
#6
Adam W Meier, David B Auyong, Stanley C Yuan, Shin-E Lin, James M Flaherty, Neil A Hanson
BACKGROUND AND OBJECTIVES: Adductor canal blocks (ACBs) are associated with improved analgesia, preserved quadriceps strength, and decreased length of hospitalization after total knee arthroplasty (TKA). However, controversy remains regarding the ideal location of a continuous block within the adductor canal, and it remains unclear whether similar clinical benefits are obtained irrespective of block location. In this randomized, double-blind, noninferiority study, we hypothesized that a continuous proximal ACB provides postoperative analgesia that is no worse than a continuous distal ACB...
November 14, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29140914/sequencing-effects-of-neuromuscular-training-on-physical-fitness-in-youth-elite-tennis-players
#7
Jaime Fernandez-Fernandez, Urs Granacher, David Sanz-Rivas, Jose Manuel Sarabia Marín, Jose Luis Hernandez-Davo, Manuel Moya
Fernandez-Fernandez, J, Granacher, U, Sanz-Rivas, D, Sarabia Marín, JM, Hernandez-Davo, JL, and Moya, M. Sequencing effects of neuromuscular training on physical fitness in youth elite tennis players. J Strength Cond Res XX(X): 000-000, 2017-The aim of this study was to analyze the effects of a 5-week neuromuscular training (NMT) implemented before or after a tennis session in prepubertal players on selected components of physical fitness. Sixteen elite and well-trained tennis players with a mean age of 12...
November 14, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29140913/sex-differences-in-aerobic-fitness-in-top-class-soccer-referees
#8
Carlo Castagna, Mario Bizzini, Stefano DʼOttavio, Susana C Araújo Póvoas
Castagna, C, Bizzini, M, D'Ottavio, S, and Araújo Póvoas, SC. Gender differences in aerobic fitness in top-class soccer referees. J Strength Cond Res XX(X): 000-000, 2017-The aim of this study was to assess the aerobic-fitness differences between male and female top-class soccer field referees (FRs). This with the purpose to provide cutoff values useful for training prescription in female FRs. Forty female top-class FRs (age 34.18 ± 3.50 years and 5 ± 3.9 years international refereeing experience) and 52 male FRs (age 38...
November 14, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29140912/reliable-testing-battery-for-assessing-physical-qualities-of-elite-academy-rugby-league-players
#9
Nick Dobbin, Richard Hunwicks, Jamie Highton, Craig Twist
Dobbin, N, Hunwicks, R, Highton, J, and Twist, C. Reliable testing battery for assessing physical qualities of elite academy rugby league players. J Strength Cond Res XX(X): 000-000, 2017-This study assessed the interday reliability of a testing battery for the assessment of physical qualities of rugby league players. Fifty players (age 17.1 ± 1.1 years; stature 181.3 ± 6.3 cm; and body mass 89.0 ± 11.6 kg) from 3 Super League academies participated in this study. Tests of countermovement jump performance, 10- and 20-m sprint performance, change of direction, medicine ball throw, and a modified Yo-Yo Intermittent Recovery Test Level 1 (prone Yo-Yo IR1) were completed on 3 separate occasions...
November 14, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29140910/polygenic-profile-and-exercise-induced-muscle-damage-by-a-competitive-half-ironman
#10
Juan Del Coso, Juan J Salinero, Beatriz Lara, César Gallo-Salazar, Francisco Areces, David Herrero, Carlos Puente
Del Coso, J, Salinero, JJ, Lara, B, Gallo-Salazar, C, Areces, F, Herrero, D, and Puente, C. Polygenic profile and exercise-induced muscle damage by a competitive half-ironman. J Strength Cond Res XX(X): 000-000, 2017-To date, it is still unknown why some individuals develop higher levels of muscle damage than other individuals, despite participating in exercise with comparable levels of physical intensity. The aim of this investigation was to analyze 7 single-nucleotide polymorphisms (SNPs) that are candidates to explain individual variations in the level of muscle damage attained during a half-ironman competition...
November 14, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29140719/effects-of-different-etching-methods-and-bonding-procedures-on-shear-bond-strength-of-orthodontic-metal-brackets-applied-to-different-cad-cam-ceramic-materials
#11
S Kutalmış Buyuk, Ahmet Serkan Kucukekenci
OBJECTIVE: To investigate the shear bond strength (SBS) of orthodontic metal brackets applied to different types of ceramic surfaces treated with different etching procedures and bonding agents. MATERIALS AND METHODS: Monolithic CAD/CAM ceramic specimens (N = 120; n = 40 each group) of feldspathic ceramic Vita Mark II, resin nanoceramic Lava Ultimate, and hybrid ceramic Vita Enamic were fabricated (14 × 12 × 3 mm). Ceramic specimens were separated into four subgroups (n = 10) according to type of surface treatment and bonding onto the ceramic surface...
November 15, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/29140693/nonadiabatic-dynamics-of-cycloparaphenylenes-with-td-dftb-surface-hopping
#12
Ljiljana Stojanovic, Saadullah G Aziz, Rifaat Hassan Hilal, Felix Plasser, Thomas A Niehaus, Mario Barbatti
We implemented a version of the decoherence-corrected fewest switches surface hopping based on linear-response time-dependent density functional tight binding (TD-DFTB), enhanced by transition density analysis. The method has been tested for the gas-phase relaxation dynamics of two cycloparaphenylene molecules, [8]CPP and [10]CPP, explaining some important features of their nonadiabatic dynamics, such as the origin of their long fluorescence lifetimes (related to the slow radiative emission from the S1 state) and the trend of increasing the fluorescence rate with the molecular size (related to an increase in the S1-S0 energy gaps and oscillator strengths in the larger molecule)...
November 15, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29140679/a-green-approach-to-improving-the-strength-and-flame-retardancy-of-poly-vinyl-alcohol-clay-aerogels-incorporating-bio-based-gelatin
#13
Yu-Tao Wang, Hai-Bo Zhao, Kimberly C Degracia, Lin-Xuan Han, Hua Sun, Mingze Sun, Yu-Zhong Wang, David A Schiraldi
Bio-based gelatins were used to improve the compressive and flammability properties poly(vinyl alcohol)/montmorillonite (PVA/MMT) aerogels, fabricated using a simple and environmentally-friendly freeze-drying method. Due to the excellent compatibility and strong interfacial adhesion between PVA and gelatin, the compressive moduli of aerogels were enhanced dramatically with the incorporation of gelatin. PVA/MMT/porcine gelatin aerogels exhibit compressive modulus values as much as 12.4 MPa, nearly 300% that of the control PVA/MMT aerogel...
November 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29140660/assessing-the-relative-influence-and-efficacy-of-public-and-private-food-safety-regulation-regimes-comparing-codex-and-global-g-a-p-standards
#14
Sam F Halabi, Ching-Fu Lin
An extensive global system of private food regulation is under construction, one that exceeds conventional regulation thought of as being driven by public authorities like FDA and USDA in the U.S. or the Food Standards Agency in the UK. Agrifood and grocer organizations, in concert with some farming groups, have been the primary designers of this new food regulatory regime. These groups have established alliances that compete with national regulators in complex ways. This article analyzes the relationship between public and private sources of food safety regulation by examining standards adopted by the Codex Alimentarius Commission, a food safety organization jointly run by the Food and Agricultural Organization and the World Health Organization and GlobalG...
2017: Food and Drug Law Journal
https://www.readbyqxmd.com/read/29140653/outsource-power-import-safety-challenges-and-opportunities-of-the-u-s-china-food-safety-regulatory-cooperation
#15
Ching-Fu Lin
The United States has a high stake in China’s serious food safety problem, as food products of Chinese origin have dominated the U.S. food market in numerous areas and continue to grow. The conclusion of the U.S.-China Food Safety Agreement (“the Agreement”) has allowed FDA to strengthen regulatory cooperation with its Chinese counterpart in various aspects. The Agreement also paves the way for the implementation of the new regulatory tools incorporated in FSMA, especially in the cross-border context...
2017: Food and Drug Law Journal
https://www.readbyqxmd.com/read/29140580/enhanced-biological-fixation-of-ligaments-to-bone-tissues-utilizing-chitin-fabrics
#16
Hisaya Nomata, Michiko Nakaishi, Kazuo Takakuda
In ligament reconstruction involving anterior cruciate ligament surgery, biological fixation between the transferred ligament and bone tissue is critical for achieving successful outcomes. Here, we administered chitin fabrics into the bone tunnels and evaluated their efficacy in promoting biological fixation. An animal model on the rat's patellar ligament was employed. First, bone tunnels were created in the lateral condyle of the femur. The ligament was then separated from the tibial tuberosity, and half was inserted into the tunnel and fixed with the use of end button...
November 15, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29140500/the-persuasion-network-is-modulated-by-drug-use-risk-and-predicts-anti-drug-message-effectiveness
#17
Richard Huskey, J Michael Mangus, Benjamin O Turner, René Weber
While a persuasion network has been proposed, little is known about how network connections between brain regions contribute to attitude change. Two possible mechanisms have been advanced. One hypothesis predicts that attitude change results from increased connectivity between structures implicated in affective and executive processing in response to increases in argument strength. A second functional perspective suggests that highly arousing messages reduce connectivity between structures implicated in the encoding of sensory information, which disrupts message processing and thereby inhibits attitude change...
November 11, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29140377/influence-of-the-prosthetic-index-on-fracture-resistance-of-morse-taper-dental-implants
#18
Karla Zancopé, Caio César Dias Resende, Carolina Guimarães Castro, Rafael Calixto Salatti, Flávio Domingues das Neves
PURPOSE: Manufacturers have inserted a prosthetic index, an internal hexagon to guide prosthetic components inside Morse taper implants. However, it is still unclear if this mechanism could decrease the mechanical strength of Morse taper implants. The aim of this study was to evaluate the influence of the prosthetic index inside Morse taper implants on fracture resistance compared with nonindexed implants. MATERIALS AND METHODS: Fifty-seven Morse taper implants, with 11...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29140296/microstructure-mechanical-and-tribological-properties-of-oxide-dispersion-strengthened-high-entropy-alloys
#19
Xinyu Liu, Hangboce Yin, Yi Xu
A novel metal matrix composite CrMnFeCoNi with Y₂O₃ as reinforcement phase was designed and manufactured by mechanical alloying and spark plasma sintering. After sintering at 900 °C for 5 min, the microstructure consisted of a FCC matrix and Y₂O₃ nanoparticles. The addition of 0.25 wt % Y₂O₃ increased the room temperature tensile strength of the CrMnFeCoNi base from 868 MPa to 1001 MPa, while the mechanical properties of the addition of 0.5 wt % Y₂O₃ composite decreased. In the meantime, the addition of Y₂O₃ had no significant influence on the coefficient of friction, while the addition of 0...
November 15, 2017: Materials
https://www.readbyqxmd.com/read/29140292/anisotropic-failure-strength-of-shale-with-increasing-confinement-behaviors-factors-and-mechanism
#20
Cheng Cheng, Xiao Li, Haitao Qian
Some studies reported that the anisotropic failure strength of shale will be weakened by increasing confinement. In this paper, it is found that there are various types of anisotropic strength behaviors. Four types of anisotropic strength ratio ( S A 1 ) behaviors and three types of anisotropic strength difference ( S A 2 ) behaviors have been classified based on laboratory experiments on nine groups of different shale samples. The cohesion c w and friction angle ϕ w of the weak planes are proven to be two dominant factors according to a series of bonded-particle discrete element modelling analyses...
November 15, 2017: Materials
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