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https://www.readbyqxmd.com/read/28346851/aquatic-therapy-for-people-with-lymphedema-a-systematic-review-and-meta-analysis
#1
Wai Yeung, Adam I Semciw
BACKGROUND: Aquatic therapy has several proposed benefits for people with lymphedema. A systematic review of the evidence for aquatic therapy in lymphedema management has not been conducted. METHOD AND RESULTS: Systematic review and meta-analysis were conducted. Five electronic databases were searched to identify randomized controlled trials (RCTs) of people with lymphedema, which compared aquatic therapy with other lymphedema interventions. Qualitative analysis was undertaken where quantitative analysis was not possible...
March 27, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28346701/effect-of-resistance-training-with-vibration-and-compression-on-the-formation-of-muscle-and-bone
#2
Christoph Zinner, Bettina Baessler, Kilian Weiss, Jasmine Ruf, Guido Michels, Hans-Christer Holmberg, Billy Sperlich
INTRODUCTION: In this study we investigated the effects of resistance training with vibration in combination with leg compression to restrict blood flow on strength, muscle oxygenation, muscle mass, and bone formation. METHODS: Twelve participants were tested before and after 12 weeks of resistance training with application of vibration (VIBRA; 1-2 mm, 30 Hz) to both legs and compression (∼35 mm Hg, VIBRA+COMP) to only 1 leg. RESULTS: VIBRA+COMP and VIBRA improved 1 repetition maximum (1-RM), increased the number of repetitions preceding muscle exhaustion, enhanced cortical bone mass, and lowered the mass and fat fraction in the thigh, with no changes in total muscle mass...
March 27, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28346689/peripheral-and-central-fatigue-after-high-intensity-resistance-circuit-training
#3
Gonzalo Márquez, Salvador Romero-Arenas, Cristian Marín-Pagán, Antonio Vera-Ibañez, Miguel FernáNdez Del Olmo, Wolfgang Taube
INTRODUCTION: The aim of this study was to investigate the effects of high intensity resistance circuit (HIRC) and traditional strength training (TST) on neuromuscular fatigue and metabolic responses. METHODS: Twelve trained young subjects performed HIRC and TST in a counterbalanced order with 1 week rest in-between. The amount of workload and the inter-set time for each local muscle group were matched (180 s), however, the time between successive exercises differed...
March 27, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28346612/inner-strength-osteopathic-medical-students-reflect-on-resiliency
#4
Karen J Nichols
No abstract text is available yet for this article.
April 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28346602/attitudes-of-family-medicine-program-directors-toward-osteopathic-residents-under-the-single-accreditation-system
#5
Laura K Hempstead, Todd D Shaffer, Karen B Williams, Lt Col James Arnold
BACKGROUND: Between 2015 and 2020, residency programs accredited through the American Osteopathic Association (AOA) are preparing the single graduate medical education (GME) system through the Accreditation Council for Graduate Medical Education (ACGME). OBJECTIVES: (1) To assess the attitudes of family medicine program directors in programs accredited dually by the AOA and ACGME (AOA/ACGME) or ACGME only toward the clinical and academic preparedness of osteopathic residency candidates and (2) to determine program director attitudes toward the perceived value of osteopathic-focused education, including osteopathic manipulative treatment (OMT) curricula...
April 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28346572/effectiveness-of-cardiac-rehabilitation-for-prevention-and-treatment-of-sarcopenia-in-patients-with-cardiovascular-disease-a-retrospective-cross-sectional-analysis
#6
H Harada, H Kai, H Niiyama, Y Nishiyama, A Katoh, N Yoshida, Y Fukumoto, H Ikeda
OBJECTIVE: Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, with the risk of frailty and poor quality of life. This study aimed to clarify the clinical characteristics of sarcopenia and to investigate the effects of comprehensive cardiac rehabilitation (CCR), including nutrition, physical exercise and medication, in patients with cardiovascular disease (CVD). METHODS: We retrospectively studied 322 inpatients with CVD (age 72±12 years)...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346563/delivery-of-nutritious-meals-to-elderly-receiving-home-care-feasibility-and-effectiveness
#7
K F M Denissen, L M J Janssen, S J P M Eussen, M C J M van Dongen, N E G Wijckmans, N D M van Deurse, P C Dagnelie
BACKGROUND/OBJECTIVES: Elderly with functional disabilities are at increased risk of inadequate dietary intake. Little is known about the effectiveness of interventions aimed at improving their dietary intake and nutritional status, nor about the determinants of successful implementation. We performed a feasibility study to evaluate the implementation and effectiveness of a home delivery service providing nutritious meals. DESIGN: Quasi-experimental, with participants allocated to treatment group based on municipality of residence...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346548/kinetics-of-light-induced-ordering-and-deformation-in-lc-azobenzene-containing-materials
#8
Vladimir Toshchevikov, Tatiana Petrova, Marina Saphiannikova
Azobenzene-containing smart materials are able to transform the energy of light into directional mechanical stress. We develop a theory of time-dependent light-induced ordering and deformation in azobenzene materials starting from the kinetic equations of photoisomerization. The liquid crystalline (LC) interactions between rod-like trans-isomers are taken into account. Angular selectivity of the photoisomerization known as an "angular hole burning" or the Weigert effect leads to the light-induced ordering and deformation of the azobenzene materials...
March 27, 2017: Soft Matter
https://www.readbyqxmd.com/read/28346524/rare-mutations-and-potentially-damaging-missense-variants-in-genes-encoding-fibrillar-collagens-and-proteins-involved-in-their-production-are-candidates-for-risk-for-preterm-premature-rupture-of-membranes
#9
Bhavi P Modi, Maria E Teves, Laurel N Pearson, Hardik I Parikh, Piya Chaemsaithong, Nihar U Sheth, Timothy P York, Roberto Romero, Jerome F Strauss
Preterm premature rupture of membranes (PPROM) is the leading identifiable cause of preterm birth with ~ 40% of preterm births being associated with PPROM and occurs in 1% - 2% of all pregnancies. We hypothesized that multiple rare variants in fetal genes involved in extracellular matrix synthesis would associate with PPROM, based on the assumption that impaired elaboration of matrix proteins would reduce fetal membrane tensile strength, predisposing to unscheduled rupture. We performed whole exome sequencing (WES) on neonatal DNA derived from pregnancies complicated by PPROM (49 cases) and healthy term deliveries (20 controls) to identify candidate mutations/variants...
2017: PloS One
https://www.readbyqxmd.com/read/28346489/gonadotropin-releasing-hormone-receptor-gnrhr-gene-knock-out-normal-growth-and-development-of-sensory-motor-and-spatial-orientation-behavior-but-altered-metabolism-in-neonatal-and-prepubertal-mice
#10
Ellen R Busby, Nancy M Sherwood
Gonadotropin-releasing hormone (GnRH) is important in the control of reproduction, but its actions in non-reproductive processes are less well known. In this study we examined the effect of disrupting the GnRH receptor in mice to determine if growth, metabolism or behaviors that are not associated with reproduction were affected. To minimize the effects of other hormones such as FSH, LH and sex steroids, the neonatal-prepubertal period of 2 to 28 days of age was selected. The study shows that regardless of sex or phenotype in the Gnrhr gene knockout line, there was no significant difference in the daily development of motor control, sensory detection or spatial orientation among the wildtype, heterozygous or null mice...
2017: PloS One
https://www.readbyqxmd.com/read/28346410/quality-of-tcr-signaling-determined-by-differential-affinities-of-enhancers-for-the-composite-batf-irf4-transcription-factor-complex
#11
Arifumi Iwata, Vivek Durai, Roxane Tussiwand, Carlos G Briseño, Xiaodi Wu, Gary E Grajales-Reyes, Takeshi Egawa, Theresa L Murphy, Kenneth M Murphy
Variable strengths of signaling via the T cell antigen receptor (TCR) can produce divergent outcomes, but the mechanism of this remains obscure. The abundance of the transcription factor IRF4 increases with TCR signal strength, but how this would induce distinct types of responses is unclear. We compared the expression of genes in the TH2 subset of helper T cells to enhancer occupancy by the BATF-IRF4 transcription factor complex at varying strengths of TCR stimulation. Genes dependent on BATF-IRF4 clustered into groups with distinct TCR sensitivities...
March 27, 2017: Nature Immunology
https://www.readbyqxmd.com/read/28346269/cohort-variation-in-selection-during-pregnancy-and-risk-of-selected-birth-defects-among-males
#12
Tim A Bruckner, Deborah Karasek, Wei Yang, Gary M Shaw, Ralph A Catalano
BACKGROUND: The literature theorizes, but does not test, that variation over time in selective loss in utero affects the observed count of live-born birth defects cases. We test the hypothesis that the risk of birth defects among live-born males varies inversely with the strength of selection against males in utero. METHODS: We identified a subset of six birth defect phenotypes among males from the California Birth Defects Monitoring Program, an active surveillance system for over 490,000 male singletons born in eight California counties from 1986 through 2004...
March 23, 2017: Epidemiology
https://www.readbyqxmd.com/read/28346201/a-pilot-stability-study-of-dehydroepiandrosterone-rapid-dissolving-tablets-prepared-by-extemporaneous-compounding
#13
Steven D Rush, Charlene Vernak, Fang Zhao
Dehydroepiandrosterone supplementation is used to treat a variety of conditions. Rapid-dissolving tablets are a relatively novel choice for compounded dehydroepiandrosterone dosage forms. While rapid-dissolving tablets offer ease of administration, there are uncertainties about the physical and chemical stability of the drug and dosage form during preparation and over long-term storage. This study was designed to evaluate the stability of dehydroepiandrosterone rapid-dissolving tablets just after preparation and over six months of storage...
January 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28346197/basics-of-compounding-with-dilutions-and-concentrates
#14
Loyd V Allen
Pharmacists use various sources for obtaining the active pharmaceutical ingredient for compounding medications. In many cases, it is the pure drug (United States Pharmacopeia, National Formulary, or similar grade); in some cases, it can be a commercial dosage form; and, in some cases, it may be a dilution or concentrate. If the drug is not present at full strength, then adjustments may be necessary to obtain the required quantity of drug. Also, in many cases, it is necessary to use a dilution or a concentrate of a drug due to safety and quality reasons...
January 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28346017/strong-in-the-face-of-adversity
#15
Simoni Binoy
Palliative care provides holistic care to individuals in life-threatening or life-limiting conditions. This narrative describes the journey of Kanchan. A strong lady and a doting mother, she came to the hospital by choice, in immense pain and with swelling. Her narrative illustrates how the palliative approach draws out the inner strengths of individuals by focusing on their issues and needs. Kanchan was able to benefit from physiotherapy to reduce the risk of lymphoedema after surgery for breast cancer. Her narrative illustrates how she found comfort and relief, ably supported by the dedicated hospital team...
March 27, 2017: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/28346002/quality-assessment-of-fluconazole-capsules-and-oral-suspensions-compounded-by-pharmacies-located-in-the-united-states
#16
Carine M Laporte, Crisanta Cruz-Espindola, Kamoltip Thungrat, Anthea E Schick, Thomas P Lewis, Dawn M Boothe
OBJECTIVE To evaluate pharmaceutical characteristics (strength or concentration, accuracy, and precision), physical properties, and bacterial contamination of fluconazole compounded products. SAMPLE Fluconazole compounded products (30- and 240-mg capsules; 30- and 100-mg/mL oral suspensions) from 4 US veterinary compounding pharmacies. PROCEDURES Fluconazole compounded products were ordered 3 times from each of 4 pharmacies at 7- or 10-day intervals. Generic fluconazole products (50- and 200-mg tablets; 10- and 40-mg/mL oral suspensions) served as references...
April 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28345879/vibrational-probes-from-small-molecule-solvatochromism-theory-and-experiments-to-applications-in-complex-systems
#17
Bartosz Błasiak, Casey H Londergan, Lauren J Webb, Minhaeng Cho
The vibrational frequency of a chosen normal mode is one of the most accurately measurable spectroscopic properties of molecules in condensed phases. Accordingly, infrared absorption and Raman scattering spectroscopy have provided valuable information on both distributions and ensemble-average values of molecular vibrational frequencies, and these frequencies are now routinely used to investigate structure, conformation, and even absolute configuration of chemical and biological molecules of interest. Recent advancements in coherent time-domain nonlinear vibrational spectroscopy have allowed the study of heterogeneous distributions of local structures and thermally driven ultrafast fluctuations of vibrational frequencies...
March 27, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28345866/biocompatible-hydroxylated-boron-nitride-nanosheets-polyvinyl-alcohol-interpenetrating-hydrogels-with-enhanced-mechanical-and-thermal-responses
#18
Lin Jing, Hongling Li, Roland Yingjie Tay, Bo Sun, Siu Hon Tsang, Olivier Cometto, Jinjun Lin, Edwin Hang Tong Teo, Alfred Iing Yoong Tok
Polyvinyl alcohol (PVA) hydrogels with tissue-like viscoelasticity, excellent biocompatibility and high hydrophilicity have been considered as promising cartilage replacement materials. However, lack of sufficient mechanical properties is a critical barrier to their usage as load-bearing cartilage substitutes. Herein, we report hydroxylated boron nitride nanosheets (OH-BNNS)/PVA interpenetrating hydrogels by cyclically freezing/thawing the aqueous mixture of PVA and highly hydrophilic OH-BNNS (up to 0.6 mg/mL, two times the highest reported so far)...
March 27, 2017: ACS Nano
https://www.readbyqxmd.com/read/28345778/comparison-of-the-efficacy-of-perineal-and-intravaginal-biofeedback-assisted-pelvic-floor-muscle-exercises-in-women-with-urodynamic-stress-urinary-incontinence
#19
Aysun Özlü, Necmettin Yıldız, Özer Öztekin
OBJECTIVE: To assess the effectiveness of intravaginal pressure biofeedback (P-BF) and perineal electromyographic biofeedback (EMG-BF) assisted pelvic floor muscle (PFM) exercises in women with stress urinary incontinence (SUI). MATERIAL AND METHODS: Fifty-three women with SUI were randomized into three groups as follows: the Group 1 received PFM home exercise program alone (n:18); the Group 2 received PFM home exercise program plus intravaginal P-BF assisted PFM exercise program (n:17); and the Group 3 received PFM home exercise program plus perineal EMG-BF assisted PFM exercise program (n:18)...
March 27, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28345754/second-to-fourth-digit-ratio-2d-4d-is-unrelated-to-measures-of-somatic-reproductive-effort-among-young-men-from-cebu-the-philippines
#20
Alexander V Georgiev, Calen P Ryan, Lee T Gettler, Thomas W McDade, Christopher W Kuzawa
OBJECTIVES: A low second-to-fourth (2D:4D) digit ratio, a retrospective marker of high prenatal androgens, predicts increased investment in costly sexually dimorphic traits in men in some studies, although results are mixed. Here we test the hypothesis that the association of low 2D:4D ratios with increased muscularity and decreased adiposity depends on current testosterone (T) levels, such that digit ratio will be a particularly strong predictor of outcomes among men exhibiting a mating-effort-oriented endocrinological profile (high T)...
March 27, 2017: American Journal of Physical Anthropology
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