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https://www.readbyqxmd.com/read/28441766/fat-mass-is-positively-associated-with-estimated-hip-bone-strength-among-chinese-men-aged-50-years-and-above-with-low-levels-of-lean-mass
#1
Guiyuan Han, Yu-Ming Chen, Hua Huang, Zhanyong Chen, Lipeng Jing, Su-Mei Xiao
This study investigated the relationships of fat mass (FM) and lean mass (LM) with estimated hip bone strength in Chinese men aged 50-80 years (median value: 62.0 years). A cross-sectional study including 889 men was conducted in Guangzhou, China. Body composition and hip bone parameters were generated by dual-energy X-ray absorptiometry (DXA). The relationships of the LM index (LMI) and the FM index (FMI) with bone phenotypes were detected by generalised additive models and multiple linear regression. The associations between the FMI and the bone variables in LMI tertiles were further analysed...
April 24, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28441679/the-drivers-of-discretionary-utilization-clinical-history-versus-physician-supply
#2
Gregory W Ruhnke, Willard G Manning, David T Rubin, David O Meltzer
PURPOSE: Because the effect of physician supply on utilization remains controversial, literature based on non-Medicare populations is sparse, and a physician supply expansion is under way, the potential for physician-induced demand across diverse populations is important to understand. A substantial proportion of gastrointestinal endoscopies may be inappropriate. The authors analyzed the impact of physician supply, practice patterns, and clinical history on esophagogastroduodenoscopy (EGD, defined as discretionary) among patients hospitalized with lower gastrointestinal bleeding (LGIB)...
May 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28441672/how-to-lead-the-way-through-complexity-constraint-and-uncertainty-in-academic-health-science-centers
#3
Susan J Lieff, Francis J Yammarino
Academic medicine is in an era of unprecedented and constant change due to fluctuating economies, globalization, emerging technologies, research, and professional and educational mandates. Consequently, academic health science centers (AHSCs) are facing new levels of complexity, constraint, and uncertainty. Currently, AHSC leaders work with competing academic and health service demands and are required to work with and are accountable to a diversity of stakeholders. Given the new challenges and emerging needs, the authors believe the leadership methods and approaches AHSCs have used in the past that led to successes will be insufficient...
May 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28441494/the-role-of-the-reducing-agent-in-the-electroless-deposition-of-copper-on-functionalized-sams
#4
Ashley Ann Ellsworth, Amy Victoria Walker
Metallized organic layer constructs have a wide range of technological applications. Electroless deposition is an attractive technique by which to deposit metal overlayers because it is inexpensive and can be performed low temperatures compatible with organic materials. Amine borane reducing agents are versatile which are capable of depositing metals, semiconductors and even insulators. We have investigated the role of amine borane reducing agents in the electroless deposition of copper on -CH3, -OH, and -COOH terminated SAMs adsorbed on gold using time-of-flight secondary ion mass spectrometry, optical microscopy and complementary MP2 calculations...
April 25, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28441442/the-effects-of-a-resistance-vs-an-aerobic-single-session-on-attention-and-executive-functioning-in-adults
#5
Ayelet Dunsky, Mona Abu-Rukun, Sharon Tsuk, Tzvi Dwolatzky, Rafi Carasso, Yael Netz
Evidence from recent studies showed that acute aerobic exercise results in improvements in different cognitive functions. The goal of this study was to assess the influence of acute bouts of aerobic versus resistance exercise on attention and executive function in adults. Thirty-nine physically active adults (age = 52±8 yr) served as participants. Each participant visited the laboratory four times: on the first visit participants performed a cognitive test (NeuroTrax) followed by an aerobic fitness assessment, as well as maximal strength test composed of six exercises...
2017: PloS One
https://www.readbyqxmd.com/read/28441410/creating-and-parameterizing-patient-specific-deep-brain-stimulation-pathway-activation-models-using-the-hyperdirect-pathway-as-an-example
#6
Kabilar Gunalan, Ashutosh Chaturvedi, Bryan Howell, Yuval Duchin, Scott F Lempka, Remi Patriat, Guillermo Sapiro, Noam Harel, Cameron C McIntyre
BACKGROUND: Deep brain stimulation (DBS) is an established clinical therapy and computational models have played an important role in advancing the technology. Patient-specific DBS models are now common tools in both academic and industrial research, as well as clinical software systems. However, the exact methodology for creating patient-specific DBS models can vary substantially and important technical details are often missing from published reports. OBJECTIVE: Provide a detailed description of the assembly workflow and parameterization of a patient-specific DBS pathway-activation model (PAM) and predict the response of the hyperdirect pathway to clinical stimulation...
2017: PloS One
https://www.readbyqxmd.com/read/28441344/collagenous-extracellular-matrix-biomaterials-for-tissue-engineering-lessons-from-the-common-sea-urchin-tissue
#7
REVIEW
Kheng Lim Goh, David F Holmes
Scaffolds for tissue engineering application may be made from a collagenous extracellular matrix (ECM) of connective tissues because the ECM can mimic the functions of the target tissue. The primary sources of collagenous ECM material are calf skin and bone. However, these sources are associated with the risk of having bovine spongiform encephalopathy or transmissible spongiform encephalopathy. Alternative sources for collagenous ECM materials may be derived from livestock, e.g., pigs, and from marine animals, e...
April 25, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28441315/an-overview-of-chronic-spinal-pain-revisiting-diagnostic-categories-and-exploring-an-evolving-role-for-neurostimulation
#8
Ashwini Sharan, Jonathan Riley, Christian Hoelscher
STUDY DESIGN: Topic Overview OBJECTIVE.: To describe the varied etiologies resulting in chronic spinal pain and review the current available evidence for treatments. SUMMARY OF BACKGROUND DATA: Chronic pain conditions, especially those that affect the axial back and radiate to the extremities, affect a large population. This results in pronounced disability and a high socioeconomic burden. Our understanding of the underlying mechanisms for chronic pain is limited...
April 24, 2017: Spine
https://www.readbyqxmd.com/read/28441275/peer-reviewers-are-our-strength
#9
Matthew D Barber
No abstract text is available yet for this article.
May 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28441237/noninvasive-ventilation-in-acute-hypoxemic-nonhypercapnic-respiratory-failure-a-systematic-review-and-meta-analysis
#10
Xiu-Ping Xu, Xin-Chang Zhang, Shu-Ling Hu, Jing-Yuan Xu, Jian-Feng Xie, Song-Qiao Liu, Ling Liu, Ying-Zi Huang, Feng-Mei Guo, Yi Yang, Hai-Bo Qiu
OBJECTIVE: To evaluate the effectiveness of noninvasive ventilation in patients with acute hypoxemic nonhypercapnic respiratory failure unrelated to exacerbation of chronic obstructive pulmonary disease and cardiogenic pulmonary edema. DATA SOURCES: PubMed, EMBASE, Cochrane library, Web of Science, and bibliographies of articles were retrieved inception until June 2016. STUDY SELECTION: Randomized controlled trials comparing application of noninvasive ventilation with standard oxygen therapy in adults with acute hypoxemic nonhypercapnic respiratory failure were included...
April 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28441059/effectiveness-of-neuromuscular-training-based-on-the-neuromuscular-risk-profile
#11
Timothy E Hewett, Kevin R Ford, Yingying Y Xu, Jane Khoury, Gregory D Myer
BACKGROUND: The effects of targeted neuromuscular training (TNMT) on movement biomechanics associated with the risk of anterior cruciate ligament (ACL) injuries are currently unknown. Purpose/Hypotheses: To determine the effectiveness of TNMT specifically designed to increase trunk control and hip strength. The hypotheses were that (1) TNMT would decrease biomechanical and neuromuscular factors related to an increased ACL injury risk and (2) TNMT would decrease these biomechanical and neuromuscular factors to a greater extent in athletes identified as being at a high risk for future ACL injuries...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28441055/ex-vivo-biomechanical-evaluation-of-pigeon-columba-livia-cadaver-intact-humeri-and-ostectomized-humeri-stabilized-with-caudally-applied-titanium-locking-plate-or-stainless-steel-nonlocking-plate-constructs
#12
Brett G Darrow, Jeffrey J Biskup, Joseph P Weigel, Michael P Jones, Xie Xie, Peter K Liaw, Josh L Tharpe, Aashish Sharma, Dayakar Penumadu
OBJECTIVE To evaluate mechanical properties of pigeon (Columba livia) cadaver intact humeri versus ostectomized humeri stabilized with a locking or nonlocking plate. SAMPLE 30 humeri from pigeon cadavers. PROCEDURES Specimens were allocated into 3 groups and tested in bending and torsion. Results for intact pigeon humeri were compared with results for ostectomized humeri repaired with a titanium 1.6-mm screw locking plate or a stainless steel 1.5-mm dynamic compression plate; the ostectomized humeri mimicked a fracture in a thin cortical bone...
May 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28441050/comparison-of-platelet-function-and-viscoelastic-test-results-between-healthy-dogs-and-dogs-with-naturally-occurring-chronic-kidney-disease
#13
Alicia Dudley, Julie K Byron, Mary Jo Burkhard, Emma Warry, Julien Guillaumin
OBJECTIVE To compare platelet function and viscoelastic test results between healthy dogs and dogs with chronic kidney disease (CKD) to assess whether dogs with CKD have platelet dysfunction and altered blood coagulation. ANIMALS 10 healthy control dogs and 11 dogs with naturally occurring CKD. PROCEDURES Blood and urine were collected once from each dog for a CBC, serum biochemical analysis, urinalysis, and determination of the urine protein-to-creatinine ratio, prothrombin time, activated partial thromboplastin time, plasma fibrinogen concentration, and antithrombin activity...
May 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28440813/instability-of-default-mode-network-connectivity-in-major-depression-a-two-sample-confirmation-study
#14
T Wise, L Marwood, A M Perkins, A Herane-Vives, R Joules, D J Lythgoe, W-M Luh, S C R Williams, A H Young, A J Cleare, D Arnone
Major depression is associated with altered static functional connectivity in various brain networks, particularly the default mode network (DMN). Dynamic functional connectivity is a novel tool with little application in affective disorders to date, and holds the potential to unravel fluctuations in connectivity strength over time in major depression. We assessed stability of connectivity in major depression between the medial prefrontal cortex (mPFC) and posterior cingulate cortex (PCC), key nodes in the DMN that are implicated in ruminative cognitions...
April 25, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28440763/recommended-vitamin-d-levels-in-the-general-population
#15
Mariela Varsavsky, Pedro Rozas Moreno, Antonio Becerra Fernández, Inés Luque Fernández, José Manuel Quesada Gómez, Verónica Ávila Rubio, Antonia García Martín, María Cortés Berdonces, Silvia Naf Cortés, Manuel Romero Muñoz, Rebeca Reyes García, Esteban Jódar Gimeno, Manuel Muñoz Torres
OBJECTIVE: To provide recommendations based on evidence on the management of vitaminD deficiency in the general population. PARTICIPANTS: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology. METHODS: Recommendations were formulated using the GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) to describe both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed) using the term VitaminD and the name of each issue...
March 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28440761/recommendations-on-the-effect-of-antidiabetic-drugs-in-bone
#16
Pedro Rozas-Moreno, Rebeca Reyes-García, Esteban Jódar-Gimeno, Mariela Varsavsky, Inés Luque-Fernández, María Cortés-Berdonces, Manuel Muñoz-Torres
OBJECTIVE: To provide recommendations on the effect of antidiabetic drugs on bone fragility to help select the most adequate antidiabetic treatment, especially in diabetic patients with high risk of fracture. PARTICIPANTS: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology. METHODS: The GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) was used to establish both the strength of recommendations and the quality of evidence...
March 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28440662/step-tracking-with-goals-increases-children-s-weight-loss-in-behavioral-intervention
#17
Amanda E Staiano, Robbie A Beyl, Daniel S Hsia, Amber R Jarrell, Peter T Katzmarzyk, Savarra Mantzor, Robert L Newton, Patrice Tyson
BACKGROUND: This study examined the influence of step goals with pedometers to improve children's weight loss, physical activity, and psychosocial health during obesity treatment. METHODS: Overweight and obese children ages 8-17 years (n = 105) participated in a 10-week family-based weight management intervention, including physical activity, nutrition, and behavioral modification. A quasi-experimental design was used to group eight cohorts into three conditions: no pedometer (n = 24), pedometer only (n = 25), and pedometer with step goals (i...
April 25, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28440630/a-hydrolytically-stable-luminescent-cationic-metal-organic-framework-for-highly-sensitive-and-selective-sensing-of-chromate-anion-in-natural-water-systems
#18
Wei Liu, Yanlong Wang, Zhuanling Bai, Yuxiang Li, Yaxing Wang, Lanhua Chen, Lin Xu, Juan Diwu, Zhifang Chai, Shuao Wang
The effective detection of chromate anion in aqueous solution is highly desirable due to its high solubility, environmental mobility, carcinogenicity, and bioaccumulation effect. New strategy for precise detection of chromate anion in the presence of large excess of other anions such as Cl-, NO3-, HCO3- in drinking water and natural water systems remains a challenge. Herein, a hydrolytically stable cationic luminescent europium(III) based metal organic framework (MOF) 1 is successfully synthesized and investigated as a luminescent sensor which exhibits instant and selective luminescence quenching property toward CrO42- in aqueous solutions...
April 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28440627/composite-micro-posts-with-high-dry-adhesion-strength
#19
Helen K Minsky, Kevin T Turner
Interfaces with enhanced and tunable adhesion have applications in a broad range of fields, including microtransfer printing of semiconductors, grippers on robots, and component handling in manufacturing. Here, a composite post structure with a stiff core and compliant shell is used to achieve enhanced adhesion under normal loading. Loading the composite structure in shear significantly reduces the effective adhesion strength, thus providing tunability. The composite posts can be used as stamps in microtransfer printing processes or as building blocks of large area tunable surfaces composed of arrays of posts...
April 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28440577/variable-developmental-delays-and-characteristic-facial-features-a-novel-7p22-3p22-2-microdeletion-syndrome
#20
Andrea C Yu, Regina M Zambrano, Ingrid Cristian, Sue Price, Birgitta Bernhard, Marc Zucker, Sunita Venkateswaran, Jean McGowan-Jordan, Christine M Armour
Isolated 7p22.3p22.2 deletions are rarely described with only two reports in the literature. Most other reported cases either involve a much larger region of the 7p arm or have an additional copy number variation. Here, we report five patients with overlapping microdeletions at 7p22.3p22.2. The patients presented with variable developmental delays, exhibiting relative weaknesses in expressive language skills and relative strengths in gross, and fine motor skills. The most consistent facial features seen in these patients included a broad nasal root, a prominent forehead a prominent glabella and arched eyebrows...
April 25, 2017: American Journal of Medical Genetics. Part A
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