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https://www.readbyqxmd.com/read/27908497/the-use-of-an-inkjet-injection-technique-in-immunoassays-by-quantitative-on-line-electrophoretically-mediated-microanalysis
#1
Weifei Zhang, Sifeng Mao, Jianmin Yang, Hulie Zeng, Hizuru Nakajima, Shungo Kato, Katsumi Uchiyama
The paper describes a new online quantitative electrophoretically mediated microanalysis (EMMA) for use in immunoassays based on the unique drop-by-drop introduction of a sample by means of an inkjet for capillary electrophoresis (CE). Plugs of a fluorescein-labeled antibody (Anti-humanIgG-DyL550) and human IgG were alternately injected into a capillary using the inkjet, followed by the merging of the plugs and the subsequent immune reaction. The antigen-antibody complex that was formed in the merged zone was then separated by CE...
November 23, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27903600/improved-accuracy-of-cefepime-susceptibility-testing-for-esbl-producing-enterobacteriaceae-using-an-on-demand-digital-dispensing-method
#2
Kenneth P Smith, Thea Brennan-Krohn, Susan Weir, James E Kirby
Extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae generally cannot be treated with penicillins and cephalosporins. However, some later generation cephalosporins, including cefepime, are poorly hydrolyzed by specific ESBL enzymes, and certain strains demonstrate in vitro susceptibility to these agents, potentially affording additional treatment opportunities. Moreover, the ability to adjust both dose and dosing interval of β-lactam agents allows treatment of strains with elevated minimal inhibitory concentrations (MICs) formerly classified in the intermediate range...
November 30, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27876146/vertical-flow-paper-sers-system-for-therapeutic-drug-monitoring-of-flucytosine-in-serum
#3
Adam G Berger, Stephen M Restaino, Ian M White
A number of life-saving drugs require therapeutic drug monitoring (TDM) for safe and effective use. Currently, however, TDM is performed using sophisticated analytical techniques relegated to central labs, increasing the cost per test and time to answer. Here, using a novel vertical flow membrane system with inkjet-printed surface enhanced Raman sensors, along with a portable spectrometer, we demonstrate a low cost and easy to use device to quantify levels of flucytosine, an antifungal that requires TDM for effective patient care, from undiluted human serum...
January 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27848979/inkjet-printing-of-tio2-alooh-heterostructures-for-the-formation-of-interference-color-images-with-high-optical-visibility
#4
Aleksandr V Yakovlev, Valentin A Milichko, Evgeny A Pidko, Vladimir V Vinogradov, Alexandr V Vinogradov
This paper describes a practical approach for the fabrication of highly visible interference color images using sol-gel ink technique and a common desktop inkjet printer. We show the potential of titania-boehmite inks for the production of optical heterostructures on various surfaces, which after drying on air produce optical solid layers with low and high refractive index. The optical properties of the surface heterostructures were adjusted following the principles of antireflection coating resulting in the enhancement of the interference color optical visibility of the prints by as much as 32%...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27830827/additive-manufacturing-of-micrometric-crystallization-vessels-and-single-crystals
#5
Oded Halevi, Hui Jiang, Christian Kloc, Shlomo Magdassi
We present an all-additive manufacturing method that is performed at mild conditions, for the formation of organic single crystals at specific locations, without any photolithography prefabrication process. The method is composed of two steps; inkjet printing of a confinement frame, composed of a water soluble electrolyte. Then, an organic semiconductor solution is printed within the confinement to form a nucleus at a specific location, followed by additional printing, which led to the growth of a single crystal...
November 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27826523/photothermal-effect-of-gold-nanostar-patterns-inkjet-printed-on-coated-paper-substrates-with-different-permeability
#6
Mykola Borzenkov, Anni Määttänen, Petri Ihalainen, Maddalena Collini, Elisa Cabrini, Giacomo Dacarro, Piersandro Pallavicini, Giuseppe Chirico
Inkjet printing of spherical gold nanoparticles is widely applied in the fabrication of analytical and diagnostics tools. These methods could be extended to non-spherical gold nanoparticles that can efficiently release heat locally when irradiated in the near infrared (NIR) wavelength region, due to localized surface plasmon resonance (LSPR). However, this promising application requires the ability to maintain high efficiency and tunability of the NIR LSPR of the printed nanoparticles. In this study stable inks containing PEGylated gold nanostars (GNS) were fabricated and successfully inkjet-printed onto differently coated paper substrates with different porosity and permeability...
2016: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/27819652/growing-three-dimensional-biomorphic-graphene-powders-using-naturally-abundant-diatomite-templates-towards-high-solution-processability
#7
Ke Chen, Cong Li, Liurong Shi, Teng Gao, Xiuju Song, Alicja Bachmatiuk, Zhiyu Zou, Bing Deng, Qingqing Ji, Donglin Ma, Hailin Peng, Zuliang Du, Mark Hermann Rümmeli, Yanfeng Zhang, Zhongfan Liu
Mass production of high-quality graphene with low cost is the footstone for its widespread practical applications. We present herein a self-limited growth approach for producing graphene powders by a small-methane-flow chemical vapour deposition process on naturally abundant and industrially widely used diatomite (biosilica) substrates. Distinct from the chemically exfoliated graphene, thus-produced biomorphic graphene is highly crystallized with atomic layer-thickness controllability, structural designability and less noncarbon impurities...
November 7, 2016: Nature Communications
https://www.readbyqxmd.com/read/27812580/monitoring-few-molecular-binding-events-in-scalable-confined-aqueous-compartments-by-raster-image-correlation-spectroscopy-cadrics
#8
G Arrabito, F Cavaleri, V Montalbano, V Vetri, M Leone, B Pignataro
The assembly of scalable liquid compartments for binding assays in array formats constitutes a topic of fundamental importance in life sciences. This challenge can be addressed by mimicking the structure of cellular compartments with biological native conditions. Here, inkjet printing is employed to develop up to hundreds of picoliter aqueous droplet arrays stabilized by oil-confinement with mild surfactants (Tween-20). The aqueous environments constitute specialized compartments in which biomolecules may exploit their function and a wide range of molecular interactions can be quantitatively investigated...
November 4, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27812468/solution-processed-vertically-stacked-complementary-organic-circuits-with-inkjet-printed-routing
#9
Jimin Kwon, Sujeong Kyung, Sejung Yoon, Jae-Joon Kim, Sungjune Jung
The fabrication and measurements of solution-processed vertically stacked complementary organic field-effect transistors (FETs) with a high static noise margin (SNM) are reported. In the device structure, a bottom-gate p-type organic FET (PFET) is vertically integrated on a top-gate n-type organic FET (NFET) with the gate shared in-between. A new strategy has been proposed to maximize the SNM by matching the driving strengths of the PFET and the NFET by independently adjusting the dielectric capacitance of each type of transistor...
May 2016: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/27810511/modeling-the-evaporation-of-sessile-multi-component-droplets
#10
C Diddens, J G M Kuerten, C W M van der Geld, H M A Wijshoff
We extended a mathematical model for the drying of sessile droplets, based on the lubrication approximation, to binary mixture droplets. This extension is relevant for e.g. inkjet printing applications, where ink consisting of several components are used. The extension involves the generalization of an established vapor diffusion-limited evaporation model to multi-component mixtures. The different volatilities of the liquid components generate a composition gradient at the liquid-air interface. The model takes the composition-dependence of the mass density, viscosity, surface tension, mutual diffusion coefficient and thermodynamic activities into account...
October 20, 2016: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/27801455/an-inkjet-printed-roll-coated-digital-microfluidic-device-for-inexpensive-miniaturized-diagnostic-assays
#11
Christopher Dixon, Alphonsus H C Ng, Ryan Fobel, Mark B Miltenburg, Aaron R Wheeler
The diagnosis of infectious disease is typically carried out at the point-of-care (POC) using the lateral flow assay (LFA). While cost-effective and portable, LFAs often lack the clinical sensitivity and specificity required for accurate diagnoses. In response to this challenge, we introduce a new digital microfluidic (DMF) platform fabricated using a custom inkjet printing and roll-coating process that is scalable to mass production. The performance of the new devices is on par with that of traditional DMF devices fabricated in a cleanroom, with a materials cost for the new devices of only US $0...
November 1, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27788012/deposition-of-colloidal-drops-containing-ellipsoidal-particles-competition-between-capillary-and-hydrodynamic-forces
#12
Dong-Ook Kim, Min Pack, Han Hu, Hyoungsoo Kim, Ying Sun
Ellipsoidal particles have previously been shown to suppress the coffee-ring effect in millimeter-sized colloidal droplets. Compared to their spherical counterparts, ellipsoidal particles experience stronger adsorption energy to the drop surface where the anisotropy-induced deformation of the liquid-air interface leads to much greater capillary attractions between particles. Using inkjet-printed colloidal drops of varying drop size, particle concentration, and particle aspect ratio, the present work demonstrates how the suppression of the coffee-ring is not only a function of the particle anisotropy, but rather a competition between the propensity for particles to assemble at the drop surface via capillary interactions and the evaporation-driven particle motion to the contact line...
October 27, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27786453/three-dimensional-inkjet-printed-organic-transistors-and-integrated-circuits-with-100-yield-high-uniformity-and-long-term-stability
#13
Jimin Kwon, Yasunori Takeda, Kenjiro Fukuda, Kilwon Cho, Shizuo Tokito, Sungjune Jung
In this paper, we demonstrate three-dimensional (3D) integrated circuits (ICs) based on a 3D complementary organic field-effect transistor (3D-COFET). The transistor-on-transistor structure was achieved by vertically stacking a p-type OFET over an n-type OFET with a shared gate joining the two transistors, effectively halving the footprint of printed transistors. All the functional layers including organic semiconductors, source/drain/gate electrodes, and interconnection paths were fully inkjet-printed except a parylene dielectric which was deposited by chemical vapor deposition...
October 24, 2016: ACS Nano
https://www.readbyqxmd.com/read/27785916/how-inkjet-printing-technology-can-defeat-multidrug-resistant-pathogens
#14
Kenneth P Smith, James E Kirby
No abstract text is available yet for this article.
October 2016: Future Microbiology
https://www.readbyqxmd.com/read/27782687/assessing-task-performance-in-ffdm-dbt-and-synthetic-mammography-using-uniform-and-anthropomorphic-physical-phantoms
#15
Lynda C Ikejimba, Stephen J Glick, Kingshuk Roy Choudhury, Ehsan Samei, Joseph Y Lo
PURPOSE: The purpose of this study is to quantify the differences in detectability between full field digital mammography (FFDM), digital breast tomosynthesis (DBT), and synthetic mammography (SM) for challenging, low contrast signals, in the context of both a uniform and an anthropomorphic, textured phantom. METHODS: Images of the phantoms were acquired using a Hologic Selenia Dimensions system. Images were taken at 50%, 100%, and 200% of the dose delivered under automatic exposure control (AEC)...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27770959/microstructure-and-compression-properties-of-3d-powder-printed-ti-6al-4v-scaffolds-with-designed-porosity-experimental-and-computational-analysis
#16
Srimanta Barui, Subhomoy Chatterjee, Sourav Mandal, Alok Kumar, Bikramjit Basu
The osseointegration of metallic implants depends on an effective balance among designed porosity to facilitate angiogenesis, tissue in-growth and bone-mimicking elastic modulus with good strength properties. While addressing such twin requirements, the present study demonstrates a low temperature additive manufacturing based processing strategy to fabricate Ti-6Al-4V scaffolds with designed porosity using inkjet-based 3D powder printing (3DPP). A novel starch-based aqueous binder was prepared and the physico-chemical parameters such as pH, viscosity, and surface tension were optimized for drop-on-demand (DOD) based thermal inkjet printing...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27769385/inkjet-printed-co2-colorimetric-indicators
#17
Yanan Zhang, Loong-Tak Lim
Colorimetric CO2 indicators were prepared by printing pH dyes (M-cresol purple or phenol red, tetrabutylammonium hydroxide, ethylcellulose, 1:2 ethanol:1-butanol solvent), using a commercially available thermal inkjet printer, on either cellulose paper or plastic transparency film. Indicators inks printed on the papers had higher sensitivity to CO2, greater color change, and more producible than those printed on plastic film. Varying the print intensities of the two pH dyes resulted in multiplexed indicators with tunable sensitivity and expanded detection concentration range towards CO2...
December 1, 2016: Talanta
https://www.readbyqxmd.com/read/27752050/inkjet-printed-graphene-pedot-pss-temperature-sensors-on-a-skin-conformable-polyurethane-substrate
#18
Tiina Vuorinen, Juha Niittynen, Timo Kankkunen, Thomas M Kraft, Matti Mäntysalo
Epidermal electronic systems (EESs) are skin-like electronic systems, which can be used to measure several physiological parameters from the skin. This paper presents materials and a simple, straightforward fabrication process for skin-conformable inkjet-printed temperature sensors. Epidermal temperature sensors are already presented in some studies, but they are mainly fabricated using traditional photolithography processes. These traditional fabrication routes have several processing steps and they create a substantial amount of material waste...
October 18, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27744171/direct-patterning-of-silver-electrodes-with-2-4%C3%AE-m-channel-length-by-piezoelectric-inkjet-printing
#19
Honglong Ning, Ruiqiang Tao, Zhiqiang Fang, Wei Cai, Jianqiu Chen, Yicong Zhou, Zhennan Zhu, Zeke Zheng, Rihui Yao, Miao Xu, Lei Wang, Linfeng Lan, Junbiao Peng
The control of channel length is of great significance in the fabrication of thin film transistors (TFTs) with high-speed operation. However, achieving short channel on untreated glass by traditional piezoelectric inkjet printing is problematic due to the impacting and rebounding behaviors of droplet impinging on solid surface. Here a novel method was proposed to obtain short channel length on untreated glass by taking advantage of the difference in the retraction velocities on both sides of an ink droplet...
October 11, 2016: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/27739009/inkjet-printing-of-proteins-an-experimental-approach
#20
Miguel Montenegro-Nicolini, Víctor Miranda, Javier O Morales
Peptides and proteins represent a promissory group of molecules used by the pharmaceutical industry for drug therapy with great potential for development. However, the administration of these molecules presents a series of difficulties, making necessary the exploration of new alternatives like the buccal route of administration to improve drug therapy compliance. Although drop-on demand printers have been explored for small molecule drugs with promising results, the development of delivery systems for peptides and proteins through inkjet printing has seen little development...
October 13, 2016: AAPS Journal
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