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https://www.readbyqxmd.com/read/28432016/inkjet-printing-of-antiviral-pcl-nanoparticles-and-anticancer-cyclodextrin-inclusion-complexes-on-bioadhesive-film-for-cervical-administration
#1
Cem Varan, Henrika Wickström, Niklas Sandler, Yeşim Aktaş, Erem Bilensoy
Personalized medicine is an important treatment approach for diseases like cancer with high intrasubject variability. In this framework, printing is one of the most promising methods since it permits dose and geometry adjustment of the final product. With this study, a combination product consisting of anticancer (paclitaxel) and antiviral (cidofovir) drugs was manufactured by inkjet printing onto adhesive film for local treatment of cervical cancers as a result of HPV infection. Furthermore, solubility problem of paclitaxel was overcome by maintaining this poorly soluble drug in a cyclodextrin inclusion complex and release of cidofovir was controlled by encapsulation in polycaprolactone nanoparticles...
April 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28420248/creating-an-optimal-3d-printed-model-for-temporal-bone-dissection-training
#2
Kuniyuki Takahashi, Yuka Morita, Shinsuke Ohshima, Shuji Izumi, Yamato Kubota, Yutaka Yamamoto, Sugata Takahashi, Arata Horii
OBJECTIVE: Making a 3-dimensional (3D) temporal bone model is simple using a plaster powder bed and an inkjet printer. However, it is difficult to reproduce air-containing spaces and precise middle ear structures. The objective of this study was to overcome these problems and create a temporal bone model that would be useful both as a training tool and for preoperative simulation. METHODS: Drainage holes were made to remove excess materials from air-containing spaces, ossicle ligaments were manually changed to bony structures, and small and/or soft tissue structures were colored differently while designing the 3D models...
April 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28417631/inkjet-printed-quantum-dot-light-emitting-diodes-with-an-air-stable-hole-transport-material
#3
Zhenhua Xing, Jinyong Zhuang, Changting Wei, Dongyu Zhang, Zhong-Zhi Xie, Xiao-Ping Xu, Shun-Jun Ji, Jian-Xin Tang, Wenming Su, Zheng Cui
High efficiency quantum dots light emitting diodes (QLEDs) have been fabricated by inkjet printing with a novel cross-linkable hole transport material N,N'-(9,9'-spirobi[fluorene]-2,7-diylbis(4,1-phenylene))bis(N-phenyl-4'-vinyl-[1,1'-biphenyl]-4-amine) (SDTF). The cross-linked SDTF film has excellent solvent resistance, high thermal stability and a highest occupied molecular orbital (HOMO) level of -5.54 eV. The inkjet printed SDTF film is very smooth and uniform with a roughness as low as 0.37 nm, which is comparable with the spin-coated film (0...
April 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28406922/3d-fabrication-and-characterization-of-phosphoric-acid-scaffold-with-a-ha-%C3%AE-tcp-weight-ratio-of-60-40-for-bone-tissue-engineering-applications
#4
Yanen Wang, Kai Wang, Xinpei Li, Qinghua Wei, Weihong Chai, Shuzhi Wang, Yu Che, Tingli Lu, Bo Zhang
A key requirement for three-dimensional printing (3-DP) at room temperature of medical implants depends on the availability of printable and biocompatible binder-powder systems. Different concentration polyvinyl alcohol (PVA) and phosphoric acid solutions were chosen as the binders to make the artificial stent biocompatible with sufficient compressive strength. In order to achieve an optimum balance between the bioceramic powder and binder solution, the biocompatibility and mechanical properties of these artificial stent samples were tested using two kinds of binder solutions...
2017: PloS One
https://www.readbyqxmd.com/read/28406192/inkjet-printing-based-volumetric-display-projecting-multiple-full-colour-2d-patterns
#5
Ryuji Hirayama, Tomotaka Suzuki, Tomoyoshi Shimobaba, Atsushi Shiraki, Makoto Naruse, Hirotaka Nakayama, Takashi Kakue, Tomoyoshi Ito
In this study, a method to construct a full-colour volumetric display is presented using a commercially available inkjet printer. Photoreactive luminescence materials are minutely and automatically printed as the volume elements, and volumetric displays are constructed with high resolution using easy-to-fabricate means that exploit inkjet printing technologies. The results experimentally demonstrate the first prototype of an inkjet printing-based volumetric display composed of multiple layers of transparent films that yield a full-colour three-dimensional (3D) image...
April 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28402330/injection-modulated-polarity-conversion-by-charge-carrier-density-control-via-a-self-assembled-monolayer-for-all-solution-processed-organic-field-effect-transistors
#6
Jeongkyun Roh, Taesoo Lee, Chan-Mo Kang, Jeonghun Kwak, Philippe Lang, Gilles Horowitz, Hyeok Kim, Changhee Lee
We demonstrated modulation of charge carrier densities in all-solution-processed organic field-effect transistors (OFETs) by modifying the injection properties with self-assembled monolayers (SAMs). The all-solution-processed OFETs based on an n-type polymer with inkjet-printed Ag electrodes were fabricated as a test platform, and the injection properties were modified by the SAMs. Two types of SAMs with different dipole direction, thiophenol (TP) and pentafluorobenzene thiol (PFBT) were employed, modifying the work function of the inkjet-printed Ag (4...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28396245/application-of-a-handheld-nir-spectrometer-in-prediction-of-drug-content-in-inkjet-printed-orodispersible-formulations-containing-prednisolone-and-levothyroxine
#7
Hossein Vakili, Henrika Wickström, Diti Desai, Maren Preis, Niklas Sandler
Quality control tools to assess the quality of printable orodispersible formulations are yet to be defined. Four different orodispersible dosage forms containing two poorly soluble drugs, levothyroxine and prednisolone, were produced on two different edible substrates by piezoelectric inkjet printing. Square shaped units of 4cm(2) were printed in different resolutions to achieve an escalating drug dose by highly accurate and uniform displacement of droplets in picoliter range from the printhead onto the substrates...
April 7, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28384854/cost-effective-printing-of-laboratory-reports-biochemist-s-and-physician-s-debate-and-institutions-dilemma
#8
Arun Kumar Harith, Anil Kumar Avs, Sangeetha Sampath
INTRODUCTION: Laboratory investigations account for significant percentage of healthcare expenses. Every hospital and laboratory especially in the government sector wants to cut down the expenses on reports and offer inferior printouts of reports. The debate of printing attractive reports (clientele aspiration) Vs costs cutting (managerial issues) continues. It becomes the moral responsibility of doctors to guide the management into implementing an effective and economical option of report transcription...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28368318/low-cost-inkjet-printing-technology-for-the-rapid-prototyping-of-transducers
#9
REVIEW
Bruno Andò, Salvatore Baglio, Adi R Bulsara, Teresa Emery, Vincenzo Marletta, Antonio Pistorio
Recently, there has been an upsurge in efforts dedicated to developing low-cost flexible electronics by exploiting innovative materials and direct printing technologies. This interest is motivated by the need for low-cost mass-production, shapeable, and disposable devices, and the rapid prototyping of electronics and sensors. This review, following a short overview of main printing processes, reports examples of the development of flexible transducers through low-cost inkjet printing technology.
April 1, 2017: Sensors
https://www.readbyqxmd.com/read/28340723/an-electrochemical-sensor-device-for-measuring-blood-ammonia-at-the-point-of-care
#10
N T Brannelly, A J Killard
The level of ammonia in blood is relevant in a number of medical conditions. While ammonia is a marker of dysfunction, elevated ammonia is itself a serious medical emergency and can lead to significant and permanent neurological impairment if not addressed quickly. Blood ammonia testing is typically performed in the central laboratory. While a number of point of care devices have been developed, these are based on classical enzymatic or colorimetric principles and have not been widely adopted. In this work, an electrochemical sensor device was developed for measuring blood ammonia...
May 15, 2017: Talanta
https://www.readbyqxmd.com/read/28338700/enhanced-piezoelectric-effect-at-the-edges-of-stepped-molybdenum-disulfide-nanosheets
#11
Xiaoxue Song, Fei Hui, Keith Gilmore, Bingru Wang, Guangyin Jing, Zhongchao Fan, Enric Grustan-Gutierrez, Yuanyuan Shi, Lucia Lombardi, Stephen A Hodge, Andrea C Ferrari, Mario Lanza
The development of piezoelectric layered materials may be one of the key elements enabling expansion of nanotechnology, as they offer a solution for the construction of efficient transducers for a wide range of applications, including self-powered devices. Here, we investigate the piezoelectric effect in multilayer (ML) stepped MoS2 flakes obtained by liquid-phase exfoliation, which is especially interesting because it may allow the scalable fabrication of electronic devices using large area deposition techniques (e...
March 24, 2017: Nanoscale
https://www.readbyqxmd.com/read/28338055/fully-printable-strain-engineered-electronic-wrap-for-customizable-soft-electronics
#12
Junghwan Byun, Byeongmoon Lee, Eunho Oh, Hyunjong Kim, Sangwoo Kim, Seunghwan Lee, Yongtaek Hong
Rapid growth of stretchable electronics stimulates broad uses in multidisciplinary fields as well as industrial applications. However, existing technologies are unsuitable for implementing versatile applications involving adaptable system design and functions in a cost/time-effective way because of vacuum-conditioned, lithographically-predefined processes. Here, we present a methodology for a fully printable, strain-engineered electronic wrap as a universal strategy which makes it more feasible to implement various stretchable electronic systems with customizable layouts and functions...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28299709/inkjet-printed-paper-fluidic-devices-for-onsite-detection-of-antibiotics-using-surface-enhanced-raman-spectroscopy
#13
Stephen M Restaino, Adam Berger, Ian M White
Surface enhanced Raman spectroscopy (SERS) provides rapid and sensitive identification of small molecule analytes. Traditionally, fabrication of SERS devices is an expensive process that involves the use of micro- and nano-fabrication procedures. Further, acquisition of diverse sample types requires complex preparation procedures that limits SERS to lab-based applications. Recent innovations using plasmonic nanoparticles embedded in flexible paper substrates has allowed the expansion of SERS techniques to portable analytical procedures...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28290194/inkjet-printed-photodetector-arrays-based-on-hybrid-perovskite-ch3nh3pbi3-microwires
#14
Yang Liu, Fushan Li, Chandrasekar Perumal Veeramalai, Wei Chen, Tailiang Guo, Chaoxing Wu, Tae Whan Kim
Hybrid perovskite CH3NH3PbI3 has attracted extensive research interests in optoelectronic devices in recent years. Herein an inkjet printing method has been employed to deposit a perovskite CH3NH3PbI3 layer. By choosing the proper solvent and controlling the crystal growth rate, hybrid perovskite CH3NH3PbI3 nanowires, microwires, a network, and islands were synthesized by means of inkjet printing. Electrode-gap-electrode lateral-structured photodetectors were fabricated with these different crystals, of which a hybrid perovskite microwire-based photodetector would balance the uniformity and low defects to obtain a switching ratio of 16000%, responsivity of 1...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28282850/fully-printed-flexible-single-chip-rfid-tag-with-light-detection-capabilities
#15
Aniello Falco, Jose F Salmerón, Florin C Loghin, Paolo Lugli, Almudena Rivadeneyra
A printed passive radiofrequency identification (RFID) tag in the ultra-high frequency band for light and temperature monitoring is presented. The whole tag has been manufactured by printing techniques on a flexible substrate. Antenna and interconnects are realized with silver nanoparticles via inkjet printing. A sprayed photodetector performs the light monitoring, whereas temperature measurement comes from an in-built sensor in the silicon RFID chip. One of the advantages of this system is the digital read-out and transmission of the sensors information on the RFID tag that ensures reliability...
March 8, 2017: Sensors
https://www.readbyqxmd.com/read/28271501/preparation-of-artificial-blood-from-the-extract-of-legume-root-nodules-and-the-creation-of-artificial-latent-fingermarks-in-blood-using-artificial-blood
#16
Sungwook Hong, Chaewon Kim, Soyoung Jeon, Eunhye Lee
Distribution of homogeneous fingermarks in blood is essential for conducting proficiency tests in forensic science. Hence, the artificial blood was prepared using the root nodule extract of Glycine max plants. The reactivity of the artificial blood with widely used human blood detection reagents was tested. Artificial latent fingermarks in blood were printed using an inkjet cartridge case filled with artificial blood solution. The artificial latent fingermarks in blood were developed with amino acid-sensitive reagents and could obtain development as prominent as the image of the master fingermark saved on the computer...
March 7, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28268978/conformai-electronics-for-longitudinal-bio-sensing-in-at-home-assistive-and-rehabilitative-devices
#17
John C Batchelor, Stephen G Yeates, Alexander J Casson
Wearable electronics are revolutionizing personalized and preventative healthcare by allowing the easy, unobtrusive, and long term monitoring of a range of body parameters. Conformal electronics which attach directly to the skin in a very robust and long term manner are envisioned as the next generation of highly portable miniaturized computing devices, beyond wearables. In this paper we overview the state-of-the-art in conformal electronics created using silver nanoparticle inkjet printed techniques for home assistive and rehabilitative devices...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28251424/visualization-and-non-destructive-quantification-of-inkjet-printed-pharmaceuticals-on-different-substrates-using-raman-spectroscopy-and-raman-chemical-imaging
#18
Magnus Edinger, Daniel Bar-Shalom, Jukka Rantanen, Natalja Genina
PURPOSE: The purpose of this study was to investigate the applicability of Raman spectroscopy for visualization and quantification of inkjet-printed pharmaceuticals. METHODS: Haloperidol was used as a model active pharmaceutical ingredient (API), and a printable ink base containing lactic acid and ethanol was developed. Inkjet printing technology was used to apply haloperidol ink onto three different substrates. Custom-made inorganic compacts and dry foam, as well as marketed paracetamol tablets were used as the substrates...
March 1, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28249512/design-of-a-novel-5-dof-flexure-based-compound-alignment-stage-for-roll-to-roll-printed-electronics
#19
Weihai Chen, Shang Yang, Jingmeng Liu, Wenjie Chen, Yan Jin
Alignment stage is a pivotal component for Roll-to-Roll Printed Electronic (R2RPE), especially for Roll-to-Roll inkjet printing. This paper presents the design, modeling, and testing of a new flexure-based compound alignment stage for R2RPE. In this design, the alignment stage has 5-DOF (Degree of Freedom) motions for compensating the alignment errors and only the rotation motion about the y-axis is redundant. The stage is constructed in series by four key parts and adopts a compounded flexure structure to achieve a great performance...
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28249472/rapid-jetting-status-inspection-and-accurate-droplet-volume-measurement-for-a-piezo-drop-on-demand-inkjet-print-head-using-a-scanning-mirror-for-display-applications
#20
Dong-Youn Shin, Minsung Kim
Despite the inherent fabrication simplicity of piezo drop-on-demand inkjet printing, the non-uniform deposition of colourants or electroluminescent organic materials leads to faulty display products, and hence, the importance of rapid jetting status inspection and accurate droplet volume measurement increases from a process perspective. In this work, various jetting status inspections and droplet volume measurement methods are reviewed by discussing their advantages and disadvantages, and then, the opportunities for the developed prototype with a scanning mirror are explored...
February 2017: Review of Scientific Instruments
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