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https://www.readbyqxmd.com/read/28545223/retraction-hsia-et-al-post-intake-of-s-ethyl-cysteine-and-s-methyl-cysteine-improved-lps-induced-acute-lung-injury-in-mice-nutrients-2016-8-507
#1
https://www.readbyqxmd.com/read/28545195/perceived-risk-of-cervical-cancer-and-barriers-to-screening-among-secondary-school-female-teachers-in-al-hassa-saudi-arabia
#2
Marwa Rashad Salem, Tarek Tawfik Amin, Abdulhamid Abdulrahman Alhulaybi, Abdulaziz Sami Althafar, Rehab Ahmed Abdelhai
Background: No previous studies had addressed the perceived risk of cervical cancer (CC) and its influence on screening practices and perceived barriers in Saudi Arabia. Methods: This cross-sectional study was conducted on 506 randomly selected Saudi female secondary school teachers in Al Hassa, Saudi Arabia to assess their level of knowledge about risk factors and signs of CC in relation to perceived risk and to characterize CC screening compliance using a self-administered questionnaire. Results: Of the included female Saudi teachers, 65...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545060/signet-a-signaling-network-data-simulator-to-enable-signaling-network-inference
#3
Elizabeth A Coker, Costas Mitsopoulos, Paul Workman, Bissan Al-Lazikani
Network models are widely used to describe complex signaling systems. Cellular wiring varies in different cellular contexts and numerous inference techniques have been developed to infer the structure of a network from experimental data of the network's behavior. To objectively identify which inference strategy is best suited to a specific network, a gold standard network and dataset are required. However, suitable datasets for benchmarking are difficult to find. Numerous tools exist that can simulate data for transcriptional networks, but these are of limited use for the study of signaling networks...
2017: PloS One
https://www.readbyqxmd.com/read/28544838/granulomatosis-with-polyangiitis-presenting-with-acute-aortic-and-mitral-regurgitation-case-report-and-big-data-analysis
#4
Sadeer G Al-Kindi, M Amer Al-Aiti, Michael Yang, Richard A Josephson
Granulomatosis with polyangiitis (GPA) is a rare vasculitis that can have multisystem involvement, though cardiac involvement is very rare. The case is described of a 53-year-old woman who presented with acute aortic and mitral valve regurgitation requiring surgical intervention. Pathology from the excised aortic valve showed geographic necrosis concerning for GPA. Subsequent rheumatologic testing was positive for anti-serine proteinase 3 (PR3) antibody, consistent with GPA. A year after the valve surgery the patient was found to have a vegetation of the mitral valve and elevated PR3 antibody levels, and was successfully treated with an intensification of immunosuppression...
January 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28544836/aortic-valve-replacement-with-the-labcor-tlpb-supra%C3%A2-porcine-bioprosthesis-intermediate-clinical-and-echocardiographic-outcomes
#5
Markus Schlömicher, Zulfugar Taghiyev, Yazan Al-Jabery, Peter Lukas Haldenwang, Leif Markthaler, Vadim Moustafine, Axel Maria Laczkovics, Justus Thomas Strauch, Matthias Bechtel
BACKGROUND: The Labcor TBLP Supra™ prosthesis is a second-generation tissue valve that has evolved from the Labcor TBLP™ prosthesis, first introduced in 1984. The Supra prosthesis is a triple-composite porcine valve, with no specific anticalcification treatment being used in its production other than standard tissue fixation with 0.4% glutaraldehyde. To date, more than 100,000 Supra valves have been implanted, mainly in South America. Despite this remarkably high number of implants, only marginal data exist concerning durability and safety issues...
January 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28544815/fabrication-of-viable-and-functional-pre-vascularized-modular-bone-tissues-by-coculturing-mscs-and-huvecs-on-microcarriers-in-spinner-flasks
#6
Songjie Zhang, Min Zhou, Zhaoyang Ye, Yan Zhou, Wen-Song Tan
BACKGROUND AND AIM: Slow vascularization often impedes the viability and function of engineered bone replacements. Prevascularization is a promising way to solve this problem. In this study, a new process was developed by integrating microcarrier culture and coculture to fabricate pre-vascularized bone microtissues with mesenchymal stem cells (MSCs) and human umbilical vein endotheli-al cells (HUVECs). METHODOLOGY: Initially, coculture medium and cell ratio between MSCs and HUVECs were optimized in tissue culture plates concerning cell proliferation, osteogenesis and angiogenesis...
May 24, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28544734/cover-image-volume-173a-number-6-june-2017
#7
Toshiki Takenouchi, Tomoru Miwa, Yoshiaki Sakamoto, Yuri Sakaguchi, Tomoko Uehara, Takao Takahashi, Kenjiro Kosaki
The cover image, by Toshiki Takenouchi et al., is based on the Clinical Report Further evidence that a blepharophimosis syndrome phenotype is associated with a specific class of mutation in the ADNP gene, DOI: 10.1002/ajmg.a.38126.
June 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28544697/a-naphthalene-derivative-as-turn-on-fluorescent-chemosensor-for-the-highly-selective-and-sensitive-detection-of-al-3
#8
Zhong-Xin Zhu, Dong-Dong Yu, Zhi-Guo Liu, Ye-Wei Huang, A-Yi Zhou, Zhi-Wei Chen, Jia Sun, Xu Wang, Li-Tai Jin, Wei-Tao Cong
A Schiff base compound derived from naphthalene has been synthesized and characterized as an Al(3+) -selective fluorescent probe. The chemosensor (L) exhibits high selectively for Al(3+) in aqueous solution, even in the presence of biologically relevant cations such as Na(+) , K(+) , Ca(2+) , Mg(2+) , Pb(2+) and several transition metal ions. There was no observed interference from anions like Br(-) , Cl(-) , HSO3(-) , SO3(2-) , S2 O3(2-) , NO2(-) , CO3(2-) and AC(-) . The lowest detection limit for the chemosensor L was found to be 1...
May 22, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28544664/to-reproduce-or-work-insect-castes-emerge-from-socially-induced-changes-in-nutrition-related-genes
#9
Amy L Toth
In social species, there is a fundamental trade-off between 'me' and 'we'; that is, should I reproduce, or should I work to help others to reproduce? In this issue of Molecular Ecology, Okada et al. () delve into the evolution and genetic mechanisms of this core question, focusing on social caste formation in insects. The authors take advantage of a unique ant in the genus Diacamma, which has secondarily lost the classic, highly different queens and workers found in many other ants, bees and wasps. Instead, Diacamma ant castes are decided via aggressive dominance interactions among adult females, similar to dominance hierarchies seen in primitively social insects and many social vertebrates...
June 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28544663/from-song-dialects-to-speciation-in-white-crowned-sparrows
#10
David P L Toews
The behavioural signals used in mate selection are a key component in the evolution of premating isolating barriers and, subsequently, the formation of new species. The importance of mating signals has a long tradition of study in songbirds, where many species differ in their song characteristics. In oscine songbirds, individual birds usually learn their songs from a tutor. Mistakes during learning can help generate geographic dialects, akin to those within human language groups. In songbirds, dialect differences can often be substantial and there is an intuitive connection between the evolution of song amongst populations at a small scale, and the more substantive song differences between bird species and presumably used in species recognition...
June 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28544655/3d-bioprinting-human-induced-pluripotent-stem-cell-constructs-for-in-situ-cell-proliferation-and-successive-multilineage-differentiation
#11
Qi Gu, Eva Tomaskovic-Crook, Gordon G Wallace, Jeremy M Crook
The ability to create 3D tissues from induced pluripotent stem cells (iPSCs) is poised to revolutionize stem cell research and regenerative medicine, including individualized, patient-specific stem cell-based treatments. There are, however, few examples of tissue engineering using iPSCs. Their culture and differentiation is predominantly planar for monolayer cell support or induction of self-organizing embryoids (EBs) and organoids. Bioprinting iPSCs with advanced biomaterials promises to augment efforts to develop 3D tissues, ideally comprising direct-write printing of cells for encapsulation, proliferation, and differentiation...
May 24, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28544513/composition-antioxidant-and-anticancer-activities-of-the-essential-oil-from-fresh-and-air-dried-aerial-parts-of-pallenis-spinosa
#12
Mahmoud A Al-Qudah, Ayman M Saleh, Naif L Alhawsawi, Hala I Al-Jaber, Syed A Rizvi, Fatma U Afifi
This study was performed to determine the chemical composition, antioxidant and anticancer effects of essential oils extracted from the aerial parts of fresh (F-PSEO) and air-dried (D-PSEO) Pallenis spinosa. The composition of the oils was analyzed by GC and GC-MS, the antioxidant activity by free radical scavenging and metal chelating assays, and their cytotoxicity by a flow cytometry analysis. The primary components in both oils were sesquiterpene hydrocarbons and oxygentated sesquiterpenes. F-PSEO contained 36 different compounds; α-cadinol (16...
May 23, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28544405/trends-of-mortality-from-alzheimer-s-disease-in-the-european-union-1994-2013
#13
H Niu, I Alvarez-Alvarez, F Guillen-Grima, M J Al-Rahamneh, I Aguinaga-Ontoso
BACKGROUND AND PURPOSE: In many countries, Alzheimer's disease (AD) has gradually become a common disease in elderly populations. The aim of this study was to analyse trends of mortality caused by AD in the 28 member countries in the European Union (EU) over the last two decades. METHODS: We extracted data for AD deaths for the period 1994-2013 in the EU from the Eurostat and World Health Organization database. Age-standardized mortality rates per 100 000 were computed...
June 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28544395/morphology-and-molecular-phylogeny-of-a-new-hypotrich-ciliate-pseudourostyla-guizhouensis-sp-nov-from-southern-china-with-notes-on-a-chinese-population-of-hemicycliostyla-franzi-foissner-1987-paiva-et%C3%A2-al-2012-ciliophora-hypotricha
#14
REVIEW
Yanbo Li, Zhao Lyu, Alan Warren, Kexin Zhou, Fengchao Li, Xumiao Chen
The morphology and molecular phylogeny of a soil hypotrich ciliate, Pseudourostyla guizhouensis sp. nov., collected from southern China, were investigated. Pseudourostyla guizhouensis sp. nov. has an elongate elliptical body measuring 180-310 × 65-85 μm in vivo; invariably two right and three or four left marginal rows; six or seven dorsal kineties; adoral zone consisting of 57-70 membranelles; 12-16 frontal cirri, one buccal cirrus, 13-20 midventral pairs, two frontoterminal cirri, two pre-transverse ventral cirri, and five to seven transverse cirri...
May 22, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/28544388/healing-effect-of-controlled-anti-electromigration-on-conventional-and-high-tc-superconducting-nanowires
#15
Xavier D A Baumans, Joseph Lombardo, Jérémy Brisbois, Gorky Shaw, Vyacheslav S Zharinov, Ge He, Heshan Yu, Jie Yuan, Beiyi Zhu, Kui Jin, Roman B G Kramer, Joris Van de Vondel, Alejandro V Silhanek
The electromigration process has the potential capability to move atoms one by one when properly controlled. It is therefore an appealing tool to tune the cross section of monoatomic compounds with ultimate resolution or, in the case of polyatomic compounds, to change the stoichiometry with the same atomic precision. As demonstrated here, a combination of electromigration and anti-electromigration can be used to reversibly displace atoms with a high degree of control. This enables a fine adjustment of the superconducting properties of Al weak links, whereas in Nb the diffusion of atoms leads to a more irreversible process...
May 19, 2017: Small
https://www.readbyqxmd.com/read/28544286/early-regional-cuprizone-induced-demyelination-in-a-rat-model-revealed-with-mri
#16
Wendy Oakden, Nicholas A Bock, Alia Al-Ebraheem, Michael J Farquharson, Greg J Stanisz
The cuprizone model of demyelination is well established in the mouse as a tool for the study of the mechanisms of both demyelination and remyelination. It is often desirable, however, to have a larger model, such as the rat, especially for imaging-based studies, yet initial work has failed to show demyelination in cuprizone-fed rats. Several recent studies have demonstrated demyelination in the rat, but only in the corpus callosum. In this study, we acquired high-resolution, three-dimensional images of the whole brain every 2 weeks, using a T1 -weighted magnetization-prepared rapid acquisition gradient echo imaging sequence, optimized for myelin contrast, in order to assess myelination across the entire rat brain over a period of 8 weeks on a 1% cuprizone diet...
May 22, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28544220/gdm-shades-of-gray
#17
Robert M Silver
In this issue of BJOG, Kapur and colleagues call for all European women to undergo screening for gestational diabetes (GDM) as recommended by FIGO (Kapur et al., BJOG 2017 XX). They rightly note the adverse fetal, neonatal, and maternal effects of GDM as well as possible downstream implications for the mother and child. Their recommendations echo those of several leading organizations including FIGO. However, despite these recommendations, some European countries, communities, hospitals and clinicians do not screen all women for GDM...
May 24, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28544211/highly-luminescent-and-ultra-stable-cspbbr3-pervoskite-quantum-dots-silica-alumina-monolith
#18
Zhichun Li, Long Kong, Shouqiang Huang, Liang Li
We successfully prepared QDs-silica/alumina monolith (QDs-SAM) by a simple sol-gel reaction of Al-Si single precursors with CsPbBr3 QDs blended in toluene solution, without adding water and catalyst. The resultant transparent monolith exhibits high photoluminescence quantum yields (PLQY) up to 90%, and good photostability under strong illumination of blue light for 300 h. We demonstrated that the preliminary ligand exchange of didodecyl dimethyl ammonium bromide (DDAB) was very important to protect CsPbBr3 QDs from the surface damages during sol-gel reaction, which not only allowed us to maintain the original optical properties of CsPbBr3 QDs but also avoided the aggregation of QDs and make the monolith transparent...
May 24, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28544164/rapid-production-of-high-purity-hydrogen-fuel-through-microwave-promoted-deep-catalytic-dehydrogenation-of-liquid-alkanes-with-abundant-metals
#19
Xiangyu Jie, Sergio Gonzalez-Cortes, Tiancun Xiao, Jiale Wang, Benzhen Yao, Daniel R Slocombe, Hamid A Al-Megren, Jonathan R Dilworth, John M Thomas, Peter P Edwards
Hydrogen as an energy carrier promises a sustainable energy revolution. However, one of the greatest challenges for any future hydrogen economy is the necessity for large scale hydrogen production not involving concurrent CO2 production. The high intrinsic hydrogen content of liquid-range alkane hydrocarbons (including diesel) offers a potential route to CO2 -free hydrogen production through their catalytic deep dehydrogenation. We report here a means of rapidly liberating high-purity hydrogen by microwave-promoted catalytic dehydrogenation of liquid alkanes using Fe and Ni particles supported on silicon carbide...
May 23, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28544119/common-fibril-structures-imply-systemically-conserved-protein-misfolding-pathways-in%C3%A2-vivo
#20
Karthikeyan Annamalai, Falk Liberta, Marie-Theres Vielberg, William Close, Hauke Lilie, Karl-Heinz Gührs, Angelika Schierhorn, Rolf Koehler, Andreas Schmidt, Christian Haupt, Ute Hegenbart, Stefan Schönland, Matthias Schmidt, Michael Groll, Marcus Fändrich
Systemic amyloidosis is caused by the misfolding of a circulating amyloid precursor protein and the deposition of amyloid fibrils in multiple organs. Chemical and biophysical analysis of amyloid fibrils from human AL and murine AA amyloidosis reveal the same fibril morphologies in different tissues or organs of one patient or diseased animal. The observed structural similarities concerned the fibril morphology, the fibril protein primary and secondary structures, the presence of post-translational modifications and, in case of the AL fibrils, the partially folded characteristics of the polypeptide chain within the fibril...
May 23, 2017: Angewandte Chemie
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