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https://www.readbyqxmd.com/read/29055234/evolving-career-choice-narratives-of-new-graduate-nurses
#1
Sheri L Price, Linda McGillis Hall, Gail Tomblin Murphy, Bridget Pierce
This article describes findings from one stage of a longitudinal study of the professional socialization experiences of Millennial nurses as they prepared for graduation and transition to practice. This study employed an interpretive narrative methodology guided by Polkinghorne's theory of narrative identity. Analysis of face-to-face interviews and journal entries by Millennial nursing students uncovered the formal professional socialization experiences over four years of nursing education. Participants include six Millennial nursing student participants (born after 1980) interviewed approximately one-month aftergraduation...
October 7, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/29055200/growth-inhibition-of-rice-oryza-sativa-l-seedlings-in-ga-and-in-contaminated-acidic-soils-is-respectively-caused-by-al-and-al-in-toxicity
#2
Jeng-Yan Su, Chien-Hui Syu, Dar-Yuan Lee
Limited information exists on the effects of emerging contaminants gallium (Ga) and indium (In) on rice plant growth. This study investigated the effects on growth and uptake of Ga and In by rice plants grown in soils with different properties. Pot experiment was conducted and the rice seedlings were grown in two soils of different pH (Pc and Cf) spiked with various Ga and In concentrations. The results showed concentrations of Ga, In, and Al in soil pore water increased with Ga- or In-spiking in acidic Pc soils, significantly decreasing growth indices...
October 12, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29055137/reply-to-topical-ionic-contra-viral-therapy-comprised-of-digoxin-and-furosemide-as-a-potential-novel-treatment-approach-for-common-warts
#3
Ayman Abdelmaksoud
I read with great interest a preliminary study on new treatment for common warts conducted by Kolk et al.(1) The authors studied, for the first time, the clinical response of common warts to topical application of a fixed dose of 980 mg topical gel containing 0.125% (w/w) digoxin and 0.125% (w/w) furosemide for 7 consecutive days on the patients' lower back. Basically, topical therapy for a common dermatosis is generally welcomed particularly if showed a higher degree of safety profile and less potential off-target adverse effects...
October 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29055096/an-improved-method-for-bivariate-meta-analysis-when-within-study-correlations-are-unknown
#4
Chuan Hong, Richard D Riley, Yong Chen
Multivariate meta-analysis, which jointly analyzes multiple and possibly correlated outcomes in a single analysis, is becoming increasingly popular in recent years. An attractive feature of the multivariate meta-analysis is its ability to account for the dependence between multiple estimates from the same study. However, standard inference procedures for multivariate meta-analysis require the knowledge of within-study correlations, which are usually unavailable. This limits standard inference approaches in practice...
October 21, 2017: Research Synthesis Methods
https://www.readbyqxmd.com/read/29055089/the-importance-and-requirement-of-belowground-carbon-inputs-for-robust-estimation-of-soil-organic-carbon-dynamics-reply-to-keel-et%C3%A2-al-2017
#5
Zhongkui Luo, Enli Wang, Wenting Feng, Yiqi Luo, Jeff Baldock
In a recent paper, we assessed the legacy data reported by Skjemstad and Spouncer (2003) and found that the amount of aboveground carbon (C) input (i.e., crop residues) in Australian cropping systems was the most important factor affecting soil C change among all the assessed drivers including the quantity and quality of C inputs, climate and soil properties (Luo et al., 2017). Keel et al. (2017) argued that the C input data used in our study "may have led to important biases and critical omissions", due to: 1) ignorance of belowground C inputs from roots/rhizodeposition, and 2) use of a constant harvest index (HI) for crops...
October 20, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29055084/uneasy-to-talk-about-costs-of-stillbirth
#6
Jan Jaap H M Erwich
In this BJOG stillbirth themed issue, Campbell et al BJOG 2018 XX.XXX report on a population-based cost of illness study. Although reports on costs in healthcare are not unusual, and even quality of life studies are incorporating translations of quality of life into money-estimates, one can feel uneasy when talking about money regarding stillbirth. It seems insensitive towards the people suffering from their loss. How can one put a monetary value on a life not yet lived? However, these authors should be congratulated for building upon earlier work in their effort to tackle this difficult and long neglected topic (Heazell et al Lancet 2016;387:604-616)...
October 21, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29055055/e-cadherin-gene-polymorphisms-and-susceptibility-to-urolithiasis-in-iraqi-children
#7
HaidarAhmed Shamran, Shatha Hussein Ali, MaysaAbdulla Ali, QasimSharhan Al-Mayah, Elham Ahmed Jasim
AIM: This case/control study aimed to assess the impact of two SNPs in the promoter region of CDH1 gene (-160C>A and -347G>GA) on urinary stone formation in a sample of Iraqi children. METHODS: Forty-seven children with urolithiasisand 50 age- and gender-matched healthy controls. DNA was isolated from peripheral blood and direct sequencing was used for genotyping. RESULTS: The homozygous genotype of the SNP CHD1 -160C>A was more frequent in control than cases (18% vs 6...
October 20, 2017: Nephrology
https://www.readbyqxmd.com/read/29055051/opposing-expression-gradients-of-calcitonin-related-polypeptide-alpha-calca-cgrp%C3%AE-and-tyrosine-hydroxylase-th-in-type-ii-afferent-neurons-of-the-mouse-cochlea
#8
Jingjing Sherry Wu, Pankhuri Vyas, Elisabeth Glowatzki, Paul Albert Fuchs
Type II spiral ganglion neurons (SGNs) are small caliber, unmyelinated afferents that extend dendritic arbors hundreds of microns along the cochlear spiral, contacting many outer hair cells (OHCs). Despite these many contacts, type II afferents are insensitive to sound and only weakly depolarized by glutamate release from OHCs. Recent studies suggest that type II afferents may be cochlear nociceptors, and can be excited by ATP released during tissue damage, by analogy to somatic pain-sensing C-fibers. The present work compares the expression patterns among cochlear type II afferents of two genes found in C-fibers: calcitonin-related polypeptide alpha (Calca/Cgrpα), specific to pain-sensing C-fibers, and tyrosine hydroxylase (Th), specific to low-threshold mechanoreceptive C-fibers, which was shown previously to be a selective biomarker of type II versus type I cochlear afferents (Vyas et al, 2016)...
October 21, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29054941/unusual-cause-of-saddle-nose
#9
Ella Starobinska, Muhsen Al-Ani, Yasir Abdulqader, Konstantinos Parperis
No abstract text is available yet for this article.
October 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29054834/evaluation-of-web-based-continuing-professional-development-courses-aggregate-mixed-methods-model
#10
Arezoo Ebn Ahmady, Megan Barker, Myra Fahim, Rosa Dragonetti, Peter Selby
BACKGROUND: Many continuing professional development (CPD) Web-based programs are not explicit about underlying theory and fail to demonstrate impact. OBJECTIVE: The aim of this study was to develop and apply an aggregate mixed-methods evaluation model to describe the paradigm, theoretical framework, and methodological approaches used to evaluate a CPD course in tobacco dependence treatment, the Training Enhancement in Applied Cessation Counseling and Health (TEACH) project...
October 20, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/29054720/a-randomized-comparison-of-two-robotic-virtual-reality-simulators-and-evaluation-of-trainees-skills-transfer-to-a-simulated-robotic-urethrovesical-anastomosis-task
#11
Jen Hoogenes, Nathan Wong, Badr Al-Harbi, Kevin S Kim, Saahil Vij, Elisa Bolognone, Mackenzie Quantz, Yanbo Guo, Bobby Shayegan, Edward D Matsumoto
OBJECTIVE: To determine, via a randomized comparison study, whether robotic simulator-acquired skills transfer to performance of a urethrovesical anastomosis (UVA) on a 3D-printed bladder model using the da Vinci Robot. MATERIALS AND METHODS: Medical students, surgical residents, and fellows were recruited and divided into two groups: G1 (junior trainees) and G2 (senior trainees). Participants were randomized to identical simulator training curricula on the dV-Trainer (dV-T) or da Vinci Surgical Skills Simulator (dVSSS)...
October 17, 2017: Urology
https://www.readbyqxmd.com/read/29054696/effects-of-articaine-on-3-h-noradrenaline-release-from-cortical-and-spinal-cord-slices-prepared-from-normal-and-streptozotocin-induced-diabetic-rats-and-compared-to-lidocaine
#12
D Végh, A Somogyi, D Bányai, M Lakatos, M Balogh, M Al-Khrasani, S Fürst, E S Vizi, P Hermann
Since a significant proportion of diabetic patients have clinical or subclinical neuropathy, there may be concerns about the use of local anaesthetics. The present study was designed to determine and compare the effects of articaine, a widely used anaesthetic in dental practice, and lidocaine on the resting and axonal stimulation-evoked release of [(3)H]noradrenaline ([(3)H]NA) in prefrontal cortex slices and the release of [(3)H]NA in spinal cord slices prepared from non-diabetic and streptozocin (STZ)-induced diabetic (glucose level=22...
October 17, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/29054591/us-alone-trials-presented-during-acquisition-do-not-disrupt-classical-eyeblink-conditioning-empirical-and-computational-findings
#13
M T Allen, C E Myers, D Williams, R J Servatius
Studies of partial reinforcement in eyeblink conditioning have typically shown slower learning of a CS-US association when paired CS-US trials are interleaved with CS-alone trials. However, recent work has shown that CS-US learning is not slowed by interleaved US-alone trials. This discrepancy is surprising since both partial reinforcement protocols reduce the total number of paired CS-US trials. Previously, Kimble et al. (1955) reported that inserting a block of US-alone trials during CS-US training did not disrupt eyeblink acquisition...
October 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29054535/adipose-tissue-inflammation-in-aging
#14
REVIEW
Theresa Mau, Raymond Yung
Adipose tissue has traditionally been viewed as an organ of interest within studies of obesity and diet-associated metabolic disorders. However, as studies reveal the role white adipose tissue plays as an energy storage, a lipid metabolism site, and an adipokine secretor, it has become recognized as an organ of importance for metabolic health in both the young obese and the old obese. Within the realms of aging research, the pursuit of senolytics has taken the field's spotlight, where the clearance of senescent cells has shown to attenuate aspects of age-related disorders...
October 17, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29054465/combating-malignant-astrocytes-strategies-mitigating-tumor-invasion
#15
REVIEW
Robyn A Umans, Harald Sontheimer
Malignant gliomas are glial-derived, primary brain tumors that carry poor prognosis. Existing therapeutics are largely ineffective and dramatically affect quality of life. The standard of care details a taxing combination of surgical resection, radiation of the resection cavity, and temozolomide (TMZ) chemotherapy, with treatment extending life by only an average of months (Maher et al., 2001; Stupp et al., 2005). Despite scientific and technological advancement, surgery remains the most important treatment modality...
October 17, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/29054451/phenolic-alkaloid-oleracein-e-attenuates-oxidative-stress-and-neurotoxicity-in-alcl3-treated-mice
#16
Lingyu Li, Yanni Jiao, Tianyun Jin, Hongxiang Sun, Shaoqiang Li, Cuirong Jin, Shuiyao Hu, Jianbo Ji, Lan Xiang
AIMS: Chelation therapy and antioxidant supplements have been demonstrated to be useful in ameliorating aluminum (Al) induced neurotoxicity. Oleracein E (OE) is a phenolic antioxidant alkaloid which possesses a rare tetrahydroisoquinoline/pyrrolidone tricyclic skeleton and a catechol moiety. The aim of this study was to investigate whether OE can chelate with Al and alleviate AlCl3-induced oxidative stress and neurotoxicity. MAIN METHODS: Kunming mice were administered AlCl3 (40mg/kg/d, i...
October 17, 2017: Life Sciences
https://www.readbyqxmd.com/read/29054446/laparoscopic-common-bile-duct-exploration-versus-endoscopic-retrograde-cholangiopancreatography-for-choledocholithiasis-found-at-time-of-laparoscopic-cholecystectomy-analysis-of-a-large-integrated-health-care-system-database
#17
Mohammed H Al-Temimi, Edwin G Kim, Bindupriya Chandrasekaran, Vanessa Franz, Charles N Trujillo, Asrai Mousa, Deron J Tessier, Samir D Johna, David A Santos
No abstract text is available yet for this article.
October 5, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29054445/endostapler-versus-hem-o-lok-clip-to-secure-the-appendiceal-stump-and-mesoappendix-during-laparoscopic-appendectomy
#18
Mohammed H Al-Temimi, Mendy A Berglin, Edwin G Kim, Deron J Tessier, Samir D Johna
No abstract text is available yet for this article.
October 6, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29054370/accessibility-of-axonal-g-protein-coupled-mu-opioid-receptors-requires-conceptual-changes-of-axonal-membrane-targeting-for-pain-modulation
#19
Shaaban A Mousa, Mohammed Shaqura, Mohammed Al-Madol, Sascha Tafelski, Baled I Khalefa, Mehdi Shakibaei, Michael Schäfer
The mechanisms of axonal trafficking and membrane targeting are well established for sodium channels, which are the principle targets for perineurally applied local anaesthetics. However, they have not been thoroughly investigated for G protein coupled receptors such as mu-opioid receptors (MOR). Focusing on these axonal mechanisms, we found that axonal MOR functionality is quite distinct in two different pain states, i.e. hindpaw inflammation and nerve injury. We observed axonal membrane MOR binding and functional G protein coupling exclusively at sites of CCI nerve injury...
October 17, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29054367/monoamine-oxidase-b-inhibitor-protects-degenerating-spinal-neurons-enhances-nerve-regeneration-and-functional-recovery-in-sciatic-nerve-crush-injury-model
#20
Al-Shimali M Hussain, Waleed M Renno, Hanaa L Sadek, Noura M Kayali, Aseel Al Salem, Muddanna S Rao, Khalid M Khan
Monoamine oxidase-B (MAOB), a flavin adenine dinucleotide (FAD), is an enzyme which catalyzes the oxidation of amines. MAOB is proposed to play a major role in the pathogenesis of neurodegeneration through the production of reactive oxygen species (ROS) and neurotoxins. The present study was designed to outline the effects of the MAOB inhibitor (MAOB-I) on neuroprotection of spinal neurons, regeneration of sciatic nerve fibers, and recovery of sensory-motor functions in the sciatic nerve crush injury model...
October 17, 2017: Neuropharmacology
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