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https://www.readbyqxmd.com/read/29245172/comment-on-how-fetal-growth-restriction-and-preterm-birth-affects-cardiac-morphology-and-function-during-infancy
#1
P P Bassareo, G Mercuro
We read with great interest the recent paper by Cohen et al regarding the early morphological and functional changes induced by intrauterine growth restriction on the heart and detected during echocardiography(1). In particular, the authors found increases in left ventricular sphericity and posterior and relative wall thicknesses. They also noted that the diastolic function, measured with tissue Doppler imaging, dropped. This article is protected by copyright. All rights reserved.
December 15, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29245159/serum-sex-hormone-binding-globulin-shbg-relation-with-different-components-of-metabolic-syndrome-in-men-with-type-2-diabetes
#2
Khalid Siddiqui, Khalid Al-Rubeaan, Shaik Sarfaraz Nawaz, Khaled H Aburisheh, Anas M Zein Alaabdin, Ibrahim A Tolba
Sex hormone binding globulin (SHBG) is demonstrated to be decreased in subjects with metabolic syndrome (MetS). The aim of the present study was to investigate the association of SHBG in relation to MetS components among men with type 2 diabetes (T2D). This cross-sectional study was carried out among 429 Saudi T2D male patients aged >30 years. Metabolic syndrome was defined using International Diabetes Federation (IDF) criteria. Fasting blood glucose (FBG), HbA1c, albumin, and lipid parameter were measured...
December 15, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29245156/selection-and-targeting-of-epcam-protein-by-ssdna-aptamer
#3
Walhan Alshaer, Nida Ababneh, Mamon Hatmal, Heba Izmirli, Moujab Choukeife, Alaa Shraim, Nour Sharar, Aya Abu-Shiekah, Fadwa Odeh, Abeer Al Bawab, Abdalla Awidi, Said Ismail
Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and selectivity to targets, ranging from small molecules to whole living cells. Several aptamers have been selected for targeting cellular proteins and they have also used in developing therapeutics and diagnostic strategies. Epithelial cell adhesion molecule (EpCAM) is considered as a cancer stem cell (CSC) biomarker and one of the most promising targets for aptamer selection against CSCs...
2017: PloS One
https://www.readbyqxmd.com/read/29245154/acute-procedural-outcomes-of-orbital-atherectomy-for-the-treatment-of-profunda-femoris-artery-disease-subanalysis-of-the-confirm-registries
#4
Michael S Lee, Pratyaksh K Srivastava, Saif Al Yaseen, Daniel Heikali, John Hollowed, Ehtisham Mahmud
OBJECTIVES: We compared the angiographic outcomes of patients treated with orbital atherectomy for profunda femoris artery (PFA) and superficial femoral artery (SFA) disease from the CONFIRM I-III registries. BACKGROUND: Endovascular revascularization of the PFA is considered a high-risk procedure given that it is an important collateral vessel when the SFA becomes occluded. Data on outcomes of endovascular revascularization of calcified PFA disease are limited...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245102/random-responses-inflate-statistical-estimates-in-heavily-skewed-addictions-data
#5
Kevin M King, Dale S Kim, Connor J McCabe
BACKGROUND: Some respondents may respond at random to self-report surveys, rather than responding conscientiously (Meade and Craig, 2012), and this has only recently come to the attention of researchers in the addictions field (Godinho et al., 2016). Almost no research in the published addictions literature has reported screening for random responses. We illustrate how random responses can bias statistical estimates using simulated and real data, and how this is especially problematic in skewed data, as is common with substance use outcomes...
December 9, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29245073/synthesis-and-application-of-bismuth-ferrite-nanosheets-supported-functionalized-carbon-nanofiber-for-enhanced-electrochemical-detection-of-toxic-organic-compound-in-water-samples
#6
Sukanya Ramaraj, Sakthivel Mani, Shen-Ming Chen, Thangavelu Kokulnathan, Bih-Show Lou, M Ajmal Ali, A A Hatamleh, Fahad M A Al-Hemaid
Recently, the multiferroic material has fabulous attention in numerous applications owing to its excellent electronic conductivity, unique mechanical property, and higher electrocatalytic activity, etc. In this paper, we reported that the synthesis of bismuth ferrite (BiFeO3) nanosheets integrated functionalized carbon nanofiber (BiFeO3 NS/F-CNF) nanocomposite using a simple hydrothermal technique. Herein, the structural changes and crystalline property of prepared BiFeO3 NS/F-CNF nanocomposite were characterized using Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS)...
December 6, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29245007/less-lipid-more-commitment
#7
Manuel Llinás
Sexual differentiation of the malaria parasite is a pre-requisite for transmission from humans to the mosquito vector and has emerged as a target for intervention in eradication efforts. In this issue of Cell, a study from Marti, Clardy, and colleagues (Brancucci et al., 2017) describes a host-derived lipid lysophosphatidylcholine (LysoPC) that regulates sexual commitment.
December 14, 2017: Cell
https://www.readbyqxmd.com/read/29245006/big-role-for-a-tiny-genome
#8
Angela E Douglas
In this issue of Cell, Salem et al. demonstrate a remarkable instance of herbivory dependent on a co-evolved mutualism with specialized bacteria. Despite having a tiny genome and limited metabolic repertoire, the bacteria in Cassida beetles produce pectinases predicted to mediate degradation of plant cell walls in the insect diet.
December 14, 2017: Cell
https://www.readbyqxmd.com/read/29244976/response-to-editorial-food-for-thought-innovation-and-debate-jwc-2017-26-7-359-and-to-swanson-et-al-letter-jwc-26-9-570-571-in-response-to-above
#9
https://www.readbyqxmd.com/read/29244962/expression-of-the-frizzled-receptors-and-their-co-receptors-in-calcified-human-aortic-valves
#10
Ateeque Siddique, Bin Yu, Kashif Khan, Ryan Buyting, Hamood Al-Kindi, Hossny Alaws, Eric Rhéaume, Jean-Claude Tardif, Renzo Cecere, Adel Schwertani
The cellular mechanisms that induce calcific aortic stenosis are yet to be unravelled. Wnt signaling is increasingly being considered as a major player in the disease process. However, the presence of Wnt Frizzled receptors (Fzd) and co-receptors LRP5 and 6 in normal and diseased human aortic valves remains to be elucidated. Immunohistochemistry and qPCR were used to determine Fzd receptor expression in normal and calcified human aortic valve tissue, as well as human aortic valve interstitial cells (HAVICs) isolated from calcified and normal human aortic valves...
December 15, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29244849/nutrients-resorption-and-stoichiometry-characteristics-of-different-aged-plantations-of-larix-kaempferi-in-the-qinling-mountains-central-china
#11
Yajun Chang, Naiwei Li, Wei Wang, Xiaojing Liu, Fengfeng Du, Dongrui Yao
Elucidating the stoichiometry and resorption patterns of multiple nutrients is of essential importance to holistically understanding plant nutrition and biogeochemical cycling. Although many studies on ecological stoichiometry have been carried out, surprisingly few of them were simultaneously done on the investigation of both nutrient resorption efficiency and stoichiometry for different-aged plantations of a perennial tree. Here, both green and senesced leaf samples were collected from four Larix kaempfer plantations aged of 8, 15, 22, and 32 years in the Qinling Mountains to examine nutrients resorption efficiency and stoichiometry characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/29244780/a-practical-method-for-the-preparation-of-18f-labeled-aromatic-amino-acids-from-nucleophilic-18f-fluoride-and-stannyl-precursors-for-electrophilic-radiohalogenation
#12
Fadi Zarrad, Boris D Zlatopolskiy, Philipp Krapf, Johannes Zischler, Bernd Neumaier
In a recent contribution of Scott et al., the substrate scope of Cu-mediated nucleophilic radiofluorination with [18F]KF for the preparation of 18F-labeled arenes was extended to aryl- and vinylstannanes. Based on these findings, the potential of this reaction for the production of clinically relevant positron emission tomography (PET) tracers was investigated. To this end, Cu-mediated radiofluorodestannylation using trimethyl(phenyl)tin as a model substrate was re-evaluated with respect to different reaction parameters...
December 15, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29244769/effects-of-uv-ozone-treatment-on-sensing-behaviours-of-egfets-with-al%C3%A2-o%C3%A2-sensing-film
#13
Cuiling Sun, Ruixue Zeng, Junkai Zhang, Zhi-Jun Qiu, Dongping Wu
The effects of UV-ozone (UVO) treatment on the sensing behaviours of extended-gate field-effect transistors (EGFETs) that use Al₂O₃ as the sensing film have been investigated. The Al₂O₃ sensing films are UVO-treated with various duration times and the corresponding EGFET sensing behaviours, such as sensitivity, hysteresis, and long-term stability, are electrically evaluated under various measurement conditions. Physical analysis is also performed to characterize the surface conditions of the UVO-treated sensing films using X-ray photoelectron spectroscopy and atomic force microscopy...
December 15, 2017: Materials
https://www.readbyqxmd.com/read/29244742/fibrinogen-gamma-chain-mutations-provoke-fibrinogen-and-apolipoprotein-b-plasma-deficiency-and-liver-storage
#14
Francesco Callea, Isabella Giovannoni, Sinan Sari, Esendagli Guldal, Buket Dalgic, Gulen Akyol, Tsuyoshi Sogo, Abdulrahman Al-Hussaini, Giuseppe Maggiore, Andrea Bartuli, Renata Boldrini, Paola Francalanci, Emanuele Bellacchio
p.R375W (Fibrinogen Aguadilla) is one out of seven identified mutations (Brescia, Aguadilla, Angers, Al du Pont, Pisa, Beograd, and Ankara) causing hepatic storage of the mutant fibrinogen γ. The Aguadilla mutation has been reported in children from the Caribbean, Europe, Japan, Saudi Arabia, Turkey, and China. All reported children presented with a variable degree of histologically proven chronic liver disease and low plasma fibrinogen levels. In addition, one Japanese and one Turkish child had concomitant hypo-APOB-lipoproteinemia of unknown origin...
December 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29244612/letter-to-the-editor-regarding-the-role-of-age-sex-interaction-in-the-development-of-post-herpetic-neuralgia
#15
Cintia Muñoz-Quiles, Mónica López-Lacort, Alejandro Orrico-Sánchez, Javier Díez-Domingo
The objective of the study was to evaluate the role of age and sex and their combined effect in the development of post-herpetic neuralgia (PHN) in a large population-based study, in order to confirm the results published previously by Amicizia et al. Data were extracted from population and healthcare databases from the Valencia Region (2009-2014). Logistic regressions were implemented to estimate the effect of increasing age on the probability of developing PHN stratified by sex. From a cohort of 2,289,485 subjects ≥ 50 years, 87,086 cases of HZ were registered and 13,658 (15...
December 15, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29244183/dna-damage-and-epigenetic-alteration-in-soybean-farmers-exposed-to-complex-mixture-of-pesticides
#16
Danieli Benedetti, Barbara Lopes Alderete, Claudia Telles de Souza, Johnny Ferraz Dias, Liana Niekraszewicz, Mónica Cappetta, Wilner Martínez-López, Juliana Da Silva
Exposure to pesticides can trigger genotoxic and mutagenic processes through different pathways. However, epidemiological studies are scarce, and further work is needed to find biomarkers sensitive to the health of exposed populations. Considering that there are few evaluations of soybean farmers, the aim of this study was to assess the effects of human exposure to complex mixtures of pesticides. The alkaline comet assay modified with restriction enzyme (hOGG1: human 8-oxoguanine DNA glycosylase) was used to detect oxidised guanine, and compared with the buccal micronucleus cytome assay, global methylation, haematological parameters, biochemical analyses (serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, gamma-glutamyl-transferase and butyrylcholinesterase), and particle-induced X-ray emission (PIXE) for the analysis of inorganic elements...
December 13, 2017: Mutagenesis
https://www.readbyqxmd.com/read/29244087/reply-to-redondo-et-al
#17
Manuel J Antunes
No abstract text is available yet for this article.
December 12, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29244061/association-between-sustained-poverty-and-changes-in-body-mass-index-from-1990-to-2015-the-coronary-artery-risk-development-in-young-adults-study
#18
Tali Elfassy, M Maria Glymour, Kiarri N Kershaw, Mercedes Carnethon, Maria M Llabre, Cora E Lewis, Neil Schneiderman, Adina Zeki Al Hazzouri
We sought to determine whether sustained poverty is associated with change in body mass index (BMI) among 4,762 black and white adults of the Coronary Artery Risk Development In Young Adults study. Household income in the past year and current BMI were measured at seven visits between 1990 and 2015. Sustained poverty was the proportion of visits during which household income was below 200% of the federal poverty level (range, 0%-100%). Sustained poverty and BMI were time-updated. Mean age in 1990 was 30 years...
December 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29244053/correction-enantioselective-synthesis-of-sulfoxide-using-an-sba-15-supported-vanadia-catalyst-a-computational-elucidation-using-a-qm-mm-approach
#19
Navjot Kaur, Shuchi Gupta, Neetu Goel
Correction for 'Enantioselective synthesis of sulfoxide using an SBA-15 supported vanadia catalyst: a computational elucidation using a QM/MM approach' by Navjot Kaur et al., Phys. Chem. Chem. Phys., 2017, 19, 25059-25070.
December 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29244013/cache-and-energy-efficient-algorithms-for-nussinov-s-rna-folding
#20
Chunchun Zhao, Sartaj Sahni
BACKGROUND: An RNA folding/RNA secondary structure prediction algorithm determines the non-nested/pseudoknot-free structure by maximizing the number of complementary base pairs and minimizing the energy. Several implementations of Nussinov's classical RNA folding algorithm have been proposed. Our focus is to obtain run time and energy efficiency by reducing the number of cache misses. RESULTS: Three cache-efficient algorithms, ByRow, ByRowSegment and ByBox, for Nussinov's RNA folding are developed...
December 6, 2017: BMC Bioinformatics
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