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https://www.readbyqxmd.com/read/29330695/glucosuria-and-all-cause-mortality-among-general-screening-participants
#1
Kunitoshi Iseki, Tsuneo Konta, Koichi Asahi, Kunihiro Yamagata, Shouichi Fujimoto, Kazuhiko Tsuruya, Ichiei Narita, Masato Kasahara, Yugo Shibagaki, Toshiki Moriyama, Masahide Kondo, Chiho Iseki, Tsuyoshi Watanabe
BACKGROUND: Dipstick urine tests are used for general health screening in Japan, but how the test results (e.g., glucosuria) relate to mortality is unknown. METHODS: Subjects participated in a nationwide screening in 2008 in six districts in Japan. We identified those who might have died using the national database of death certificates from 2008 to 2012 (total registered ~ 6 million) and verified candidates with the regional National Health Insurance Agency and public health nurses...
January 12, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29330152/risk-of-infection-in-type-1-and-type-2-diabetes-compared-with-the-general-population-a-matched-cohort-study
#2
Iain M Carey, Julia A Critchley, Stephen DeWilde, Tess Harris, Fay J Hosking, Derek G Cook
OBJECTIVE: We describe in detail the burden of infections in adults with diabetes within a large national population cohort. We also compare infection rates between patients with type 1 and type 2 diabetes mellitus (T1DM and T2DM). RESEARCH DESIGN AND METHODS: A retrospective cohort study compared 102,493 English primary care patients aged 40-89 years with a diabetes diagnosis by 2008 (n = 5,863 T1DM and n = 96,630 T2DM) with 203,518 age-sex-practice-matched control subjects without diabetes...
January 12, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29329975/risk-of-suicide-and-non-fatal-self-harm-after-bariatric-surgery-results-from-two-matched-cohort-studies
#3
Martin Neovius, Gustaf Bruze, Peter Jacobson, Kajsa Sjöholm, Kari Johansson, Fredrik Granath, Johan Sundström, Ingmar Näslund, Claude Marcus, Johan Ottosson, Markku Peltonen, Lena M S Carlsson
BACKGROUND: Bariatric surgery reduces mortality, but might have adverse effects on mental health. We assessed the risk of suicide and self-harm after bariatric surgery compared with non-surgical obesity treatment. METHODS: Suicide and non-fatal self-harm events retrieved from nationwide Swedish registers were examined in two cohorts. The non-randomised, prospective Swedish Obese Subjects (SOS) study compared bariatric surgery (n=2010; 1369 vertical-banded gastroplasty, 376 gastric banding, and 265 gastric bypass) with usual care (n=2037; recruitment 1987-2001)...
January 9, 2018: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29326333/comet-a-multicomponent-home-based-disease-management-programme-versus-routine-care-in-severe-copd
#4
Romain Kessler, Pere Casan-Clara, Dieter Koehler, Silvia Tognella, Jose Luis Viejo, Roberto W Dal Negro, Salvador Díaz-Lobato, Karina Reissig, José Miguel Rodríguez González-Moro, Gilles Devouassoux, Jean-Michel Chavaillon, Pierre Botrus, Jean-Michel Arnal, Julio Ancochea, Anne Bergeron-Lafaurie, Carlos De Abajo, Winfried J Randerath, Andreas Bastian, Christian G Cornelissen, Georg Nilius, Joëlle B Texereau, Jean Bourbeau
The COPD Patient Management European Trial (COMET) investigated the efficacy and safety of a home-based COPD disease management intervention for severe COPD patients.The study was an international open-design clinical trial in COPD patients (forced expiratory volume in 1 s <50% of predicted value) randomised 1:1 to the disease management intervention or to the usual management practices at the study centre. The disease management intervention included a self-management programme, home telemonitoring, care coordination and medical management...
January 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29325121/plasma-25-hydroxyvitamin-d-and-mortality-in-patients-with-suspected-stable-angina-pectoris
#5
Eirik Degerud, Ottar Nygård, Stefan de Vogel, Rune Hoff, Gard Frodahl Tveitevåg Svingen, Eva Ringdal Pedersen, Dennis Winston Trygve Nilsen, Jan Erik Nordrehaug, Øivind Midttun, Per Magne Ueland, Jutta Dierkes
Context and objective: Vitamin D status may affect cardiovascular disease (CVD) development and survival. We studied the relationship between concentrations of the circulating biomarker 25-hydroxyvitamin D (25OHD) and all-cause and cardiovascular mortality risk. Design, Setting, Participants and main Outcome Measures: 25OHD, the sum of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2, was analysed in plasma samples from 4114 Caucasian patients with suspected stable angina pectoris, and adjusted for seasonal variation...
January 9, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29320517/explaining-the-decline-in-coronary-heart-disease-mortality-rates-in-the-slovak-republic-between-1993-2008
#6
Marek Psota, Piotr Bandosz, Eva Gonçalvesová, Mária Avdičová, Mária Bucek Pšenková, Martin Studenčan, Jarmila Pekarčíková, Simon Capewell, Martin O'Flaherty
OBJECTIVE: Between the years 1993 and 2008, mortality rates from coronary heart disease (CHD) in the Slovak Republic have decreased by almost one quarter. However, this was a smaller decline than in neighbouring countries. The aim of this modelling study was therefore to quantify the contributions of risk factor changes and the use of evidence-based medical therapies to the CHD mortality decline between 1993 and 2008. METHODS: We identified, obtained and scrutinised the data required for the model...
2018: PloS One
https://www.readbyqxmd.com/read/29314242/co-morbidities-only-account-for-a-small-proportion-of-excess-mortality-after-fracture-a-record-linkage-study-of-individual-fracture-types
#7
Weiwen Chen, Judy M Simpson, Lyn M March, Fiona M Blyth, Dana Bliuc, Thach Tran, Tuan V Nguyen, John A Eisman, Jacqueline R Center
BACKGROUND: Non-hip non-vertebral fractures (NHNV) constitute the majority of osteoporotic fractures but few studies have examined the association between these fractures, co-morbidity and mortality. OBJECTIVE: To examine the relationship between individual non-hip non-vertebral fractures, co-morbidities and mortality. METHODS: Prospective population-based cohort of 267,043 subjects (45 and Up Study, Australia) had baseline questionnaires linked to hospital administrative and all-cause mortality data from 2006 - 2013...
January 4, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29306344/preweaning-mortality-in-piglets-in-loose-housed-herds-etiology-and-prevalence
#8
C Kielland, H Wisløff, M Valheim, A K Fauske, O Reksen, T Framstad
Preweaning mortality in piglets is a welfare issue, as well as an ethical and economic concern in commercial pig farming. Studying the causes of preweaning mortality and their prevalence is necessary to reduce losses. Preweaning piglet mortality was investigated in a field study including 347 sows from 14 loose-housed Norwegian piglet-producing herds. A total of 5254 piglets were born in these herds during the study period, and 1200 piglets were necropsied. The cause of death was based on pathoanatomical diagnosis (PAD)...
January 8, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29304751/what-is-the-best-adjustment-of-appendicular-lean-mass-for-predicting-mortality-or-disability-among-japanese-community-dwellers
#9
Rei Otsuka, Yasumoto Matsui, Chikako Tange, Yukiko Nishita, Makiko Tomida, Fujiko Ando, Hiroshi Shimokata, Hidenori Arai
BACKGROUND: Age-related declines in skeletal muscle mass and strength, representing "sarcopenia," are a growing concern in aging societies. However, the prevalence of low muscle mass based on the height2-adjustment has been shown to be extremely low, and a more appropriate definition of low muscle mass is needed, particularly for Asian women. The aim of this study was to explore the most appropriate adjustment of appendicular lean mass (ALM) for predicting mortality or disability risk using ALM or any of 5 adjustments of ALM among community-dwelling Japanese...
January 5, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29298801/bmi-and-mortality-in-patients-with-new-onset-type-2-diabetes-a-comparison-with-age-and-sex-matched-control-subjects-from-the-general-population
#10
Jon Edqvist, Araz Rawshani, Martin Adiels, Lena Björck, Marcus Lind, Ann-Marie Svensson, Sofia Gudbjörnsdottir, Naveed Sattar, Annika Rosengren
OBJECTIVE: Type 2 diabetes is strongly associated with obesity, but the mortality risk related to elevated body weight in people with type 2 diabetes compared with people without diabetes has not been established. RESEARCH DESIGN AND METHODS: We prospectively assessed short- and long-term mortality in people with type 2 diabetes with a recorded diabetes duration ≤5 years identified from the Swedish National Diabetes Registry between 1998 and 2012 and five age- and sex-matched control subjects per study participant from the general population...
January 3, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29291422/the-effect-of-multifactorial-lifestyle-interventions-on-cardiovascular-risk-factors-a-systematic-review-and-meta-analysis-of-trials-conducted-in-the-general-population-and-high-risk-groups
#11
REVIEW
L G Sisti, M Dajko, P Campanella, E Shkurti, W Ricciardi, C de Waure
Cardiovascular diseases (CVDs) are the leading cause of premature mortality and disability accounting for one third of all deaths worldwide with considerable impacts on economics and on the quality of life. The evidence suggests that a multifactorial lifestyle intervention might have a role in the CVDs risk reduction, especially in the risk populations, nonetheless the effects on modifiable CVDs risk factors have not been completely explored. Our work aimed at evaluating the impact of multifactorial lifestyle interventions on cardiovascular risk modification, both in the general and risk population...
December 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29290364/association-of-sarcopenic-obesity-predicted-by-anthropometric-measurements-and-24-y-all-cause-mortality-in-elderly-men-the-kuakini-honolulu-heart-program
#12
Kiyoshi Sanada, Randi Chen, Bradley Willcox, Tomoyuki Ohara, Aida Wen, Cody Takenaka, Kamal Masaki
OBJECTIVE: The aim of this study was to investigate the association between anthropometric measurements of sarcopenic obesity and all-cause mortality. METHODS: The study included 2309 Japanese-American men ages 71 to 93 y. Mortality data were available for up to 24 y of follow-up. Sarcopenic obesity defined by three patterns of obesity indexes (body mass index [BMI], percent body fat [%BF] and waist circumference [WC]) and skeletal muscle index estimated by anthropometric measurements...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29288116/a-study-on-outcome-of-binding-pancreaticogastrostomy-following-pancreaticoduodenectomy-a-prospective-study
#13
Dronacharya Routh, Nishant Pathak, C S Naidu, A K Singh, P P Rao, Priya Ranjan
INTRODUCTION: The type of anastomosis of the pancreas following pancreaticoduodenectomy is often attributed to the reason for pancreatic leak. Results of various randomized trials comparing pancreaticojejunostomy and pancreaticogastrostomy are conflicting one suggesting advantage over the other and vice versa. In this study we intend to critically analyze a novel technique of binding pancreaticogastrostomy following pancreaticoduodenectomy. AIMS AND OBJECTIVES: The aim of this study is to see the outcome of binding pancreaticogastrostomy by evaluating the technical aspects of binding PG and study the incidence of post-operative complications...
December 26, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29281995/prevalence-and-correlates-of-frailty-in-an-older-rural-african-population-findings-from-the-haalsi-cohort-study
#14
Collin F Payne, Alisha Wade, Chodziwadziwa W Kabudula, Justine I Davies, Angela Y Chang, F Xavier Gomez-Olive, Kathleen Kahn, Lisa F Berkman, Stephen M Tollman, Joshua A Salomon, Miles D Witham
BACKGROUND: Frailty is a key predictor of death and dependency, yet little is known about frailty in sub-Saharan Africa despite rapid population ageing. We describe the prevalence and correlates of phenotypic frailty using data from the Health and Aging in Africa: Longitudinal Studies of an INDEPTH Community cohort. METHODS: We analysed data from rural South Africans aged 40 and over. We used low grip strength, slow gait speed, low body mass index, and combinations of self-reported exhaustion, decline in health, low physical activity and high self-reported sedentariness to derive nine variants of a phenotypic frailty score...
December 28, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29276410/clinical-course-of-nonalcoholic-fatty-liver-disease-an-assessment-of-severity-progression-and-outcomes
#15
Jason C Simeone, Jay P Bae, Byron J Hoogwerf, Qian Li, Axel Haupt, Ayad K Ali, Marilyn K Boardman, Beth L Nordstrom
Purpose: To identify the characteristics and initial disease severity of patients with nonalcoholic fatty liver disease (NAFLD) and assess incidence and risk factors for disease progression in a retrospective study. Methods: Patients ≥18 years of age without alcoholism or other liver diseases (eg, hepatitis B/C) were selected from Geisinger Health System electronic medical record data from 2004 to 2015. Initial disease stage was stratified into uncomplicated NAFLD, advanced fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and liver transplant using clinical biomarkers, diagnosis, and procedure codes...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/29275346/clinical-features-and-prognosis-of-patients-with-acute-non-specific-chest-pain-in-emergency-and-cardiology-departments-after-the-introduction-of-high-sensitivity-troponins-a-prospective-cohort-study
#16
Nivethitha Ilangkovan, Hans Mickley, Axel Diederichsen, Annmarie Lassen, Thomas L Sørensen, Hussam Mahmoud Sheta, Peter B Stæhr, Christian Backer Mogensen
OBJECTIVES: To determine the incidence of clinical, cardiac-related endpoints and mortality among patients presenting to an emergency or cardiology department with non-specific chest pain (NSCP), and who receive testing with a high-sensitivity troponin. A second objective was to identify risk factors for the above-noted endpoints during 12 months of follow-up. DESIGN: A prospective multicentre study. SETTING: Emergency and cardiology departments in Southern Denmark...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29262488/-estimation-of-the-impact-of-risk-factors-control-on-non-communicable-diseases-mortality-life-expectancy-and-the-labor-force-lost-in-china-in-2030
#17
X Y Zeng, Y C Li, J M Liu, Y N Liu, S W Liu, J L Qi, M G Zhou
Objective: To estimate the impact of risk factors control on non-communicable diseases (NCDs) mortality, life expectancy and the numbers of labor force lost in China in 2030. Methods: We used the results of China from Global Burden of Disease Study 2013, according to the correlation between death of NCDs and exposure of risk factors and the comparative risk assessment theory, to calculate population attributable fraction (PAF) and disaggregate deaths of NCDs into parts attributable and un-attributable. We used proportional change model to project risk factors exposure and un-attributable deaths of NCDs in 2030, then to get deaths of NCDs in 2030...
December 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29258464/evaluation-of-unplanned-dialysis-as-a-predictor-of-mortality-in-elderly-dialysis-patients-a-retrospective-data-analysis
#18
Debajyoti Roy, Anupama Roy Chowdhury, Shrikant Pande, Jia Wen Kam
BACKGROUND: Increasing numbers of elderly patients are undergoing long-term dialysis. However, the role of dialysis in survival and quality of life is unclear, and poor outcomes may be associated with comorbidities rather than with age only. The initiation of unplanned dialysis in elderly patients with chronic kidney disease (CKD) has been reported to be associated with poor survival. We evaluated patient and practice factors associated with poor survival. METHODS: We performed a retrospective analysis of 90 consecutive elderly patients (≥75 years) with CKD initiated on long-term dialysis at our renal unit between October 2010 and February 2014...
December 19, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29249533/is-prescribed-lower-extremity-weight-bearing-status-after-geriatric-lower-extremity-trauma-associated-with-increased-mortality
#19
Ida Leah Gitajn, Daniel Connelly, Daniel Mascarenhas, Stephen Breazeale, Peter Berger, Carrie Schoonover, Brook Martin, Robert V O'Toole, Raymond Pensy, Marcus Sciadini
OBJECTIVES: Evaluate whether mortality after discharge is elevated in geriatric fracture patients whose lower extremity weight-bearing is restricted. DESIGN: Retrospective cohort study SETTING: Urban Level 1 trauma center PATIENTS/PARTICIPANTS: 1746 patients >65 years of age INTERVENTION: Post-operative lower extremity weight-bearing status MAIN OUTCOME MEASURE: Mortality, as determined by the Social Security Death Index RESULTS: Univariate analysis demonstrated that patients who were weight-bearing as tolerated on bilateral lower extremities (BLE) had significantly higher 5-year mortality compared to patients with restricted weight-bearing on one lower extremity and restricted weight-bearing on BLE (30%, 21% and 22% respectively, p < 0...
December 14, 2017: Injury
https://www.readbyqxmd.com/read/29249487/association-of-body-mass-index-with-lung-transplantation-survival-in-the-united-states-following-implementation-of-the-lung-allocation-score
#20
Ramiro Fernandez, Niloufar Safaeinili, Chitaru Kurihara, David D Odell, Manu Jain, Malcolm M DeCamp, G R Scott Budinger, Ankit Bharat
BACKGROUND: The association of body mass index (BMI) with survival after lung transplantation remains controversial, owing to conflicting evidence in the literature. Previous reports have used traditional BMI categories, included patients who underwent transplantation before implementation of the lung allocation score (LAS), or were limited by single-center experiences. Here we evaluated the association of individual BMI units with short-term and long-term mortality in a large national database following implementation of the LAS...
November 20, 2017: Journal of Thoracic and Cardiovascular Surgery
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