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https://www.readbyqxmd.com/read/28645552/mortality-following-augmentation-cystoplasty-a-transitional-urologist-s-viewpoint
#1
REVIEW
D A Husmann
INTRODUCTION: Three complications have been hypothesized to increase patient mortality following enterocystoplasty: spontaneous bladder perforation, bladder neoplasia, and chronic renal failure (CRF). The present study examined risk of their occurrence and discussed ways to improve the quality of care. MATERIALS AND METHODS: The present transitional clinic followed 385 patients with a history of bladder augmentation using either ileal, sigmoid, or ascending colon...
June 3, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28645108/prognostic-factors-influencing-the-survival-of-patients-with-carcinoma-of-the-gastric-cardia-receiving-preoperative-interventional-embolization-chemotherapy
#2
Hai-Li Cao, Shu-Qiang Jin, Kai-Bing Wang, Bin Bai
The purpose of this study was to analyze the characteristics of patients with gastric cardia cancer (GCC) to identify the main factors the influence the survival rate after interventional embolization chemotherapy (IEC). One hundred and fifty-six patients with advanced GCC were treated with IEC via the left gastric artery. Survival time was defined as from the date of diagnosis until death or the end of this study in June 2015. The median survival time was 15 months (range 3 to 29 months). The Cox proportional hazard model found that patients' age (p< 0...
June 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28639706/exercise-for-pregnant-women-with-gestational-diabetes-for-improving-maternal-and-fetal-outcomes
#3
REVIEW
Julie Brown, Gilles Ceysens, Michel Boulvain
BACKGROUND: Gestational diabetes mellitus (GDM) is associated with both short- and long-term complications for the mother and her baby. Exercise interventions may be useful in helping with glycaemic control and improve maternal and infant outcomes.The original review on Exercise for diabetic pregnant women has been split into two new review titles reflecting the role of exercise for pregnant women with gestational diabetes and for pregnant women with pre-existing diabetes. Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes (this review) Exercise for pregnant women with pre-existing diabetes for improving maternal and fetal outcomes OBJECTIVES: To evaluate the effects of exercise interventions for improving maternal and fetal outcomes in women with GDM...
June 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28637727/a-protocol-for-prospective-studies-of-25-hydroxyvitamin-d-leptin-and-body-mass-index-in-relation-to-cutaneous-melanoma-incidence-and-survival
#4
Jo Steinson Stenehjem, Tom K Grimsrud, Judith R Rees, Linda Vos, Ronnie Babigumira, Marit B Veierød, Trude Eid Robsahm
INTRODUCTION: The incidence and mortality rates of cutaneous melanoma (CM) are increasing among fair-skinned populations worldwide. Ultraviolet radiation (UVR) is the principal risk factor for CM, but is also the main source of 25-hydroxyvitamin D (25(OH)D), which has been associated with reduced risk and better prognosis of some cancer types. However, both low and high 25(OH)D levels have been associated with increased risk of CM. Obesity as measured by body mass index (BMI) is associated with risk of several cancers and has also been suggested as a risk factor for CM, and may also be related to insufficient 25(OH)D and/or high leptin levels...
June 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28633384/correlates-of-dyspnoea-and-its-association-with-adverse-outcomes-in-a-cohort-of-adults-aged-80-and-over
#5
Eralda Hegendörfer, Bert Vaes, Catharina Matheï, Gijs Van Pottelbergh, Jean-Marie Degryse
Background: adults aged 80 and over, a fast growing age-group, with increased co-morbidity and frailty have not been the focus of previous research on dyspnoea. We investigate the correlates of dyspnoea and its association with adverse outcomes in a cohort of adults aged 80 and over. Methods: about 565 community-dwelling adults aged 80 and over of the BELFRAIL prospective cohort had assessment of Medical Research Council dyspnoea scale (MRC), forced expiratory volume in 1 s (FEV1), N-terminal pro-brain natriuretic peptide (NT-proBNP), physical performance tests, grip strength, 15 items geriatric depression scale, activities of daily living (ADL), body mass index (BMI) and demographics data...
June 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28626829/socioeconomic-status-as-an-effect-modifier-of-alcohol-consumption-and-harm-analysis-of-linked-cohort-data
#6
Srinivasa Vittal Katikireddi, Elise Whitley, Jim Lewsey, Linsay Gray, Alastair H Leyland
BACKGROUND: Alcohol-related mortality and morbidity are high in socioeconomically disadvantaged populations compared with individuals from advantaged areas. It is unclear if this increased harm reflects differences in alcohol consumption between these socioeconomic groups, reverse causation (ie, downward social selection for high-risk drinkers), or a greater risk of harm in individuals of low socioeconomic status compared with those of higher status after similar consumption. We aimed to investigate whether the harmful effects of alcohol differ by socioeconomic status, accounting for alcohol consumption and other health-related factors...
June 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/28626828/contribution-of-risk-factors-to-excess-mortality-in-isolated-and-lonely-individuals-an-analysis-of-data-from-the-uk-biobank-cohort-study
#7
Marko Elovainio, Christian Hakulinen, Laura Pulkki-Råback, Marianna Virtanen, Kim Josefsson, Markus Jokela, Jussi Vahtera, Mika Kivimäki
BACKGROUND: The associations of social isolation and loneliness with premature mortality are well known, but the risk factors linking them remain unclear. We sought to identify risk factors that might explain the increased mortality in socially isolated and lonely individuals. METHODS: We used prospective follow-up data from the UK Biobank cohort study to assess self-reported isolation (a three-item scale) and loneliness (two questions). The main outcomes were all-cause and cause-specific mortality...
June 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/28620089/development-and-validation-of-risk-prediction-equations-to-estimate-survival-in-patients-with-colorectal-cancer-cohort-study
#8
Julia Hippisley-Cox, Carol Coupland
Objective To develop and externally validate risk prediction equations to estimate absolute and conditional survival in patients with colorectal cancer. Design Cohort study.Setting General practices in England providing data for the QResearch database linked to the national cancer registry.Participants 44 145 patients aged 15-99 with colorectal cancer from 947 practices to derive the equations. The equations were validated in 15 214 patients with colorectal cancer from 305 different QResearch practices and 437 821 patients with colorectal cancer from the national cancer registry...
June 15, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28615933/development-of-a-nomogram-for-predicting-in-hospital-mortality-of-patients-with-exacerbation-of-chronic-obstructive-pulmonary-disease
#9
Yukiyo Sakamoto, Yasuhiro Yamauchi, Hideo Yasunaga, Hideyuki Takeshima, Wakae Hasegawa, Taisuke Jo, Yusuke Sasabuchi, Hiroki Matsui, Kiyohide Fushimi, Takahide Nagase
BACKGROUND AND OBJECTIVES: Patients with chronic obstructive pulmonary disease (COPD) often experience exacerbations of their disease, sometimes requiring hospital admission and being associated with increased mortality. Although previous studies have reported mortality from exacerbations of COPD, there is limited information about prediction of individual in-hospital mortality. We therefore aimed to use data from a nationwide inpatient database in Japan to generate a nomogram for predicting in-hospital mortality from patients' characteristics on admission...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28605423/source-3-1-year-outcomes-post-transcatheter-aortic-valve-implantation-using-the-latest-generation-of-the-balloon-expandable-transcatheter-heart-valve
#10
Olaf Wendler, Gerhard Schymik, Hendrik Treede, Helmut Baumgartner, Nicolas Dumonteil, Franz-Josef Neumann, Giuseppe Tarantini, José Luis Zamorano, Alec Vahanian
Aims: Transcatheter aortic valve implantation (TAVI) has developed from a procedure for patients with aortic stenosis inoperable or high risk for surgery, into a treatment option even for intermediate risk elderly patients. This development has been facilitated by the clinical learning curve and constant improvements of transcatheter heart valves used. We present total 1-year results of SOURCE 3, the European post-approval multicentre registry of the latest generation balloon expandable SAPIEN 3TM (Edwards Lifesciences, Irvine, CA, USA)...
June 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28604484/the-effect-of-postoperative-spinal-infections-on-patient-mortality
#11
David S Casper, Benjamin Zmistowski, Douglas A Hollern, Alan S Hilibrand, Alexander R Vaccaro, Gregory D Schroeder, Christopher K Kepler
STUDY DESIGN: Retrospective, matched cohort study OBJECTIVES.: This study aims to (a) investigate the association between SSI and mortality and (b) ascertain any factors that predict mortality in those diagnosed with SSI. SUMMARY OF BACKGROUND DATA: Despite significant efforts towards mitigation, surgical site infection (SSI), including deep infection remains a common complication following spine surgery, Considerable morbidity may be associated with infection, including hospital readmission, revision surgery, and delayed rehabilitation...
June 9, 2017: Spine
https://www.readbyqxmd.com/read/28601125/hyperuricemia-and-long-term-survival-in-patients-with-chronic-kidney-disease-undergoing-hemodialysis
#12
Tadej Petreski, Sebastjan Bevc, Robert Ekart, Radovan Hojs
INTRODUCTION: Uric acid (UA), a breakdown product of purines, has been associated with mortality in different populations. Less is known about associations between hyperuricemia and mortality in chronic kidney disease (CKD) patients, later undergoing hemodialysis (HD), during a long observation period. The aim of this study was to determine the impact of elevated UA levels on long-term (19.5 years) survival of CKD patients. METHODS: 120 CKD patients (49 female, 71 male) enrolled in our study were observed from their first visit at the patients' nephrology outpatient clinic (NOC)...
June 9, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28599979/relationship-of-energy-and-protein-adequacy-with-60-day-mortality-in%C3%A2-mechanically-ventilated-critically-ill-patients-a-prospective-observational-study
#13
Zheng-Yii Lee, Ibrahim Noor Airini, Mohd-Yusof Barakatun-Nisak
BACKGROUND & AIMS: The effect of provision of full feeding or permissive underfeeding on mortality in mechanically ventilated critically ill patients in the intensive care unit (ICU) is still controversial. This study investigated the relationship of energy and protein intakes with 60-day mortality, and the extent to which ICU length of stay and nutritional risk status influenced this relationship. METHODS: This is a prospective observational study conducted among critically ill patients aged ≥18 years, intubated and mechanically ventilated within 48 h of ICU admission and stayed in the ICU for at least 72 h...
May 19, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28593629/type-2-diabetes-adiposity-and-cancer-morbidity-and-mortality-risk-taking-into-account-competing-risk-of-non-cancer-deaths-in-a-prospective-cohort-setting
#14
Isabel Drake, Bo Gullberg, Emily Sonestedt, Tanja Stocks, Anders Bjartell, Elisabet Wirfält, Peter Wallström, Marju Orho-Melander
Type 2 diabetes (T2D) and adiposity associate with increased risk of several cancers, but the impact of competing risk of non-cancer deaths on these associations is not known. We prospectively examined participants in the Malmö Diet and Cancer Study aged 44-73 years with no history of cancer at baseline (n=26,953, 43% men). T2D was ascertained at baseline and during follow-up, and body mass index (BMI) and waist circumference (WC) at baseline. Multivariable cause-specific hazard ratios (HR) and sub-distribution hazard ratios (sHR), taking into account non-cancer deaths, were estimated using Cox- and competing risk regression...
June 8, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28591160/the-association-of-ferritin-with-cardiovascular-and-all-cause-mortality-in-community-dwellers-the-english-longitudinal-study-of-ageing
#15
Nikolaos P E Kadoglou, Jane P Biddulph, Snorri B Rafnsson, Marialena Trivella, Petros Nihoyannopoulos, Panayotes Demakakos
BACKGROUND: Ferritin constitutes a sensitive iron-storage index and multi-functional protein. Evidence on its association with mortality in general population is scarce and conflicting. We investigated the sex-specific associations of ferritin levels with all-cause and cardiovascular mortality in a population-based cohort. METHODS: Data came from the English Longitudinal Study of Ageing and the national mortality registry. The sample comprised 5,471 participants aged ≥52 years...
2017: PloS One
https://www.readbyqxmd.com/read/28588323/impact-of-body-mass-index-on-ovarian-cancer-survival-varies-by-stage
#16
Elisa V Bandera, Valerie S Lee, Bo Qin, Lorna Rodriguez-Rodriguez, C Bethan Powell, Lawrence H Kushi
BACKGROUND: Research on the effect of body mass index (BMI) on ovarian cancer survival is inconsistent, but previous studies did not consider the possible impact of ascites, bowel obstruction, or cachexia, which commonly occur in late-stage disease. METHODS: We evaluated the association of BMI, before and around the time of diagnosis, with overall and disease-specific survival in a cohort study of primary invasive epithelial ovarian cancers diagnosed from 2000 to 2013 in Kaiser Permanente Northern California (KPNC) (n=1184)...
June 6, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28583215/waist-circumference-as-a-predictor-of-mortality-in-peritoneal-dialysis-patients-a-follow-up-study-of-48-months
#17
Ana Catarina M Castro, Ana Paula Bazanelli, Fabiana B Nerbass, Lilian Cuppari, Maria A Kamimura
Body-fat gain is a common finding among peritoneal dialysis (PD) patients, and the accumulation of adipose tissue occurs predominantly in the abdominal area. Waist circumference (WC) is a reliable marker of abdominal obesity and its association with worse outcomes has been demonstrated in non-dialysis and haemodialysis patients. We aimed at investigating whether WC measurements as well as the changes over time in WC were able to predict mortality in PD patients. This prospective study included 109 patients undergoing PD (57 % male, age 52 (sd 16) years, 32 % diabetics, 48 % BMI≥25 kg/m2)...
June 6, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28578598/hyperthyroidism-hypothyroidism-and-cause-specific-mortality-in-a-large-cohort-of-women
#18
Neige My Journy, Marie-Odile Bernier, Michele M Doody, Bruce H Alexander, Martha Linet, Cari Meinhold Kitahara
BACKGROUND: The prevalence of hyperthyroidism and hypothyroidism is 0.5-4% in iodine-replete communities, but 5-10 times higher in women than men. Those conditions are associated with a broad range of metabolic disorders and cardiovascular diseases. Biological evidence of a role of thyroid hormones in carcinogenesis also exists. However, the association between thyroid dysfunction and cardiovascular disease or cancer mortality risk remains controversial. In a large cohort of women, we evaluated the associations of hyperthyroidism and hypothyroidism with cause-specific mortality after nearly 30 years of follow-up...
June 3, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28576683/management-of-acute-intra-abdominal-sepsis-caused-by-leakage-after-one-anastomosis-gastric-bypass
#19
Nathan Beaupel, Matthieu Bruzzi, Thibault Voron, Haydar A Nasser, Richard Douard, Jean-Marc Chevallier
BACKGROUND: Leakage after one-anastomosis gastric bypass (OAGB) is fortunately rare (<1%), but it remains the most severe complication. Few published data exist on this specific issue. OBJECTIVES: To analyze the results from patients who presented with acute intra-abdominal sepsis (AIAS) caused by leakage after OAGB. SETTING: A university public hospital in France. METHODS: Between October 2006 and February 2016, 17 consecutive patients with a diagnosis of AIAS caused by leakage after OAGB were included...
April 8, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28572159/apol1-risk-variants-and-cardiovascular-disease-results-from-the-aask-african-american-study-of-kidney-disease-and-hypertension
#20
Teresa K Chen, Lawrence J Appel, Morgan E Grams, Adrienne Tin, Michael J Choi, Michael S Lipkowitz, Cheryl A Winkler, Michelle M Estrella
OBJECTIVE: Among black, the apolipoprotein L1 (APOL1) risk variants have been associated with various types of kidney disease and chronic kidney disease progression. We aimed to determine whether these same risk variants also confer an increased risk for cardiovascular disease. APPROACH AND RESULTS: In a cohort of blacks with hypertension-attributed chronic kidney disease followed for up to 12 years, we used Cox proportional hazards models to estimate the relative hazard of a composite cardiovascular disease outcome (cardiovascular death or hospitalization for myocardial infarction, cardiac revascularization procedure, heart failure, or stroke) for the APOL1 high- (2 risk variants) versus low-risk (0-1 risk variant) genotypes...
June 1, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
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