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https://www.readbyqxmd.com/read/29164125/malnutrition-upon-hospital-admission-in-geriatric-patients-why-assess-it
#1
Paolo Orlandoni, Claudia Venturini, Nikolina Jukic Peladic, Annarita Costantini, Mirko Di Rosa, Claudia Cola, Natascia Giorgini, Redenta Basile, Donata Fagnani, Debora Sparvoli, Serenella David
Objective: To assess the prevalence of malnutrition according to the new ESPEN definition in a population of geriatric hospital patients and to determine how malnutrition affects the length of hospital stay (LOS) and hospital mortality. Design: A retrospective analysis of data gathered during nutritional screening surveys carried out three consecutive years, from 2012 to 2014, in an Italian geriatric research hospital (INRCA, Ancona) was performed. On the day of the study, demographic data, data on clinical conditions and the nutritional status of newly admitted patients were collected...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29161801/impact-of-sarcopenia-on-long-term-mortality-and-cardiovascular-events-in-patients-undergoing-hemodialysis
#2
Jwa-Kyung Kim, Sung Gyun Kim, Ji-Eun Oh, Young-Ki Lee, Jung-Woo Noh, Hyung Jik Kim, Young Rim Song
Background/Aims: A high body mass index (BMI) is known to correlate with better survival in patients on hemodialysis (HD). However, the impacts of body composition and sarcopenia on survival have not been well studied in this population. Methods: One hundred and forty-two prevalent HD patients were recruited and followed prospectively for up to 4.5 years. Low muscle mass (measured using a portable, whole-body, bioimpedance spectroscopic device) was defined as a lean tissue index (LTI) two standard deviations (SD) or more below the normal gender-specific mean for young people...
November 23, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29158672/lung-transplantation-and-survival-outcomes-in-patients-with-oxygen-dependent-copd-with-regard-to-their-alpha-1-antitrypsin-deficiency-status
#3
Magnus Ekström, Hanan Tanash
Background: Individuals with severe alpha-1 antitrypsin deficiency (AATD) have an increased risk of developing COPD. However, outcomes during long-term oxygen therapy (LTOT) in patients with severe AATD and hypoxemia are unknown. Patients and methods: This was a prospective, population-based, consecutive cohort study of patients on LTOT due to COPD in the period from January 1, 1987, to June 30, 2015, in the Swedish National Registry for Respiratory Failure (Swedevox)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29158157/non-alcoholic-fatty-liver-disease-associates-with-increased-overall-mortality-and-death-from-cancer-cardiovascular-disease-and-liver-disease-in-women-but-not-men
#4
You-Cheol Hwang, Hong-Yup Ahn, Sung-Woo Park, Cheol-Young Park
BACKGROUND & AIMS: It is not clear whether women vs men have increased mortality from non-alcoholic fatty liver disease (NAFLD). We investigated whether NAFLD is associated with increased overall and cause-specific deaths in a Korean population using a large health study database. METHODS: We collected data on 318,224 subjects in Korea (165,131 men and 153,093 women) 20-94 years old (mean age of 39.3 years), enrolled in the Kangbuk Samsung Health Study cohort. All subjects underwent a comprehensive annual or biennial health examination in Seoul or Suwon, South Korea, from 2002 through 2012...
November 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29155226/interaction-between-cardiovascular-risk-factors-and-body-mass-index-and-10-year-incidence-of-cardiovascular-disease-cancer-death-and-overall-mortality
#5
Maria Barroso, Albert Goday, Rafel Ramos, Alejandro Marín-Ibañez, Maria Jesús Guembe, Fernando Rigo, Maria José Tormo-Díaz, Conchi Moreno-Iribas, Joan Josep Cabré, Antonio Segura, Jose Miguel Baena-Díez, Agustín Gómez de la Cámara, José Lapetra, Miquel Quesada, María José Medrano, Jesús Berjón, Guillem Frontera, Diana Gavrila, Aurelio Barricarte, Josep Basora, José María García, Manel García-Lareo, David Lora-Pablos, Eduardo Mayoral, María Grau, Jaume Marrugat
The effect of above-normal body mass index (BMI) on health outcomes is controversial because it is difficult to distinguish from the effect due to BMI-associated cardiovascular risk factors. The objective was to analyze the impact on 10-year incidence of cardiovascular disease, cancer deaths and overall mortality of the interaction between cardiovascular risk factors and BMI. We conducted a pooled analysis of individual data from 12 Spanish population cohorts with 10-year follow-up. Participants had no previous history of cardiovascular diseases and were 35-79years old at basal examination...
November 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29155225/a-systematic-review-of-the-long-term-effectiveness-of-work-based-lifestyle-interventions-to-tackle-overweight-and-obesity
#6
REVIEW
Greta Tam, May P S Yeung
Obesity is one of the five leading global risks for mortality, accounting for 5% of deaths worldwide. Workplace health promotion programs have the potential to deliver population-level interventions combining physical activity and exercise. However, there is no recent critical review of trials on long-term effectiveness of multicomponent lifestyle interventions in the workplace targeting obesity. Good quality evidence is needed to develop optimal strategies to tackle adult obesity. 1035 studies were retrieved by literature search in MEDLINE, Embase, PSYCH INFO and Cochrane library from 2005 to September 2016...
November 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29154422/beta-blocker-dose-and-markers-of-sympathetic-activation-in-heart-failure-patients-interrelationships-and-prognostic-significance
#7
Alain Cohen-Solal, Arnold F Jacobson, Ileana L Piña
AIMS: Extent of cardiac sympathetic activation can be estimated from physiological parameters, blood biomarkers, and imaging findings. This study examined the prognostic value of three markers of sympathetic activity and their relationship to beta blocker dose in heart failure patients. METHODS AND RESULTS: A post hoc analysis of 858 heart failure subjects in the ADMIRE-HF trial was performed. Variables related to sympathetic activity were plasma norepinephrine, baseline heart rate, the heart to mediastinum (H/M) ratio of (123) I-mIBG uptake, and beta blocker dose...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29152438/barriers-to-timely-completion-of-radiation-therapy-in-patients-with-cervical-cancer-in-an-urban-tertiary-care-center
#8
Justin Cohen, Amy Harper, Elizabeth M Nichols, Gautam G Rao, Pranshu Mohindra, Dana Marie Roque
Background In 2017, there will be an estimated 12,820 women diagnosed with cervical cancer in the United States, causing an estimation of 4,210 deaths. Among U.S. women, there is a 33% greater incidence and 71% higher cervical cancer mortality in high-poverty counties when compared to low-income counties [1]. In those dispositioned to chemoradiation, treatment time of less than eight weeks is associated with compromised pelvic control. We sought to identify patient or disease characteristics and socioeconomic or psychosocial barriers that contribute to delays in treatment completion in order to formulate new policies to address these needs...
September 12, 2017: Curēus
https://www.readbyqxmd.com/read/29136442/association-between-prepregnancy-body-mass-index-and-severe-maternal-morbidity
#9
Sarka Lisonkova, Giulia M Muraca, Jayson Potts, Jessica Liauw, Wee-Shian Chan, Amanda Skoll, Kenneth I Lim
Importance: Although high body mass index (BMI) is associated with adverse birth outcomes, the association with severe maternal morbidity is unclear. Objective: To examine the association between prepregnancy BMI and severe maternal morbidity. Design, Setting, and Participants: Retrospective population-based cohort study including all singleton hospital births in Washington State, 2004-2013. Demographic data and morbidity diagnoses were obtained from linked birth certificates and hospitalization files...
November 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29136011/ten-year-experience-with-antiretroviral-treatment-in-cambodia-trends-in-patient-characteristics-and-treatment-outcomes
#10
Phirum Lay, Sokkab An, Sunpiseth Soeung, Pich Sovannary Srey, Sopheak Thai, Lutgarde Lynen, Johan van Griensven
BACKGROUND: Although HIV disease stage at ART initiation critically determines ART outcomes, few reports have longitudinally monitored this within Asia. Using prospectively collected data from a large ART program at Sihanouk Hospital Center of Hope in Cambodia, we report on the change in patient characteristics and outcomes over a ten-year period. METHODS: We conducted a retrospective analysis including all adults (≥ 18 years old) starting ART from March 2003-March 2013 in a non-governmental hospital in Phnom Penh, Cambodia...
2017: PloS One
https://www.readbyqxmd.com/read/29127228/association-between-body-mass-index-and-outcomes-after-percutaneous-coronary-intervention-in-multiethnic-south-east-asian-population-a-retrospective-analysis-of-the-malaysian-national-cardiovascular-disease-database-percutaneous-coronary-intervention-ncvd-pci
#11
Zaid Azhari, Muhammad Dzafir Ismail, Ahmad Syadi Mahmood Zuhdi, Norashikin Md Sari, Imran Zainal Abidin, Wan Azman Wan Ahmad
OBJECTIVE: To examine the relationship between body mass index (BMI) and outcomes after percutaneous coronary intervention (PCI) in a multiethnic South East Asian population. SETTING: Fifteen participating cardiology centres contributed to the Malaysian National Cardiovascular Disease Database-Percutaneous Coronary Intervention (NCVD-PCI) registry. PARTICIPANTS: 28 742 patients from the NCVD-PCI registry who had their first PCI between January 2007 and December 2014 were included...
November 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/29126583/effect-of-changes-in-physical-activity-on-risk-for-cardiac-death-in-patients-with-coronary-artery-disease
#12
Minna Lahtinen, Tomi Toukola, M Juhani Junttila, Olli-Pekka Piira, Samuli Lepojärvi, Maria Kääriäinen, Heikki V Huikuri, Mikko P Tulppo, Antti M Kiviniemi
Leisure-time physical activity (LTPA) is associated with longevity in patients with coronary artery disease (CAD). However, less is known about prognostic significance of longitudinally assessed LTPA in patients with stable CAD. The present study assessed the relationship between changes in LTPA and cardiac mortality in patients with CAD. Patients with angiographically documented CAD (n = 1,746) underwent clinical examination and echocardiography at the baseline. Lifestyle factors, including LTPA (inactive, irregularly active, active, highly active), were surveyed at baseline and after 2 years' follow-up...
October 19, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29123584/analysis-of-postoperative-morbidity-and-mortality-following-surgery-for-gastric-cancer-surgeon-volume-as-the-most-significant-prognostic-factor
#13
Maciej Ciesielski, Wiesław J Kruszewski, Jakub Walczak, Mariusz Szajewski, Jarosław Szefel, Jacek Wydra, Tomasz Buczek, Maksymilian Czerepko
Introduction: Surgical resection is the only potentially curative modality for gastric cancer and it is associated with substantial morbidity and mortality. Aim: To determine risk factors for postoperative morbidity and mortality following major surgery for gastric cancer. Material and methods: Between 1.08.2006 and 30.11.2014 in the Department of Oncological Surgery of Gdynia Oncology Centre 162 patients underwent gastric resection for adenocarcinoma...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29122528/safety-of-open-ventral-hernia-repair-in-high-risk-patients-with-metabolic-syndrome-a-multi-institutional-analysis-of-39-118-cases
#14
Dmitry Zavlin, Kevin T Jubbal, Jeffrey L Van Eps, Barbara L Bass, Warren A Ellsworth, Anthony Echo, Jeffrey D Friedman, Brian J Dunkin
BACKGROUND: Metabolic syndrome (MetS) entails the simultaneous presence of a constellation of dangerous risk factors including obesity, diabetes, hypertension, and dyslipidemia. The prevalence of MetS in Western society continues to rise and implies an elevated risk for surgical complications and/or poor surgical outcomes within the affected population. OBJECTIVE: To assess the risks and outcomes of multi-morbid patients with MetS undergoing open ventral hernia repair...
September 22, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29116212/causes-of-death-in-patients-with-severe-aortic-stenosis-an-observational-study
#15
Eri Minamino-Muta, Takao Kato, Takeshi Morimoto, Tomohiko Taniguchi, Hiroki Shiomi, Kenji Nakatsuma, Shinichi Shirai, Kenji Ando, Norio Kanamori, Koichiro Murata, Takeshi Kitai, Yuichi Kawase, Makoto Miyake, Chisato Izumi, Hirokazu Mitsuoka, Masashi Kato, Yutaka Hirano, Shintaro Matsuda, Kazuya Nagao, Tsukasa Inada, Tomoyuki Murakami, Yasuyo Takeuchi, Keiichiro Yamane, Mamoru Toyofuku, Mitsuru Ishii, Moriaki Inoko, Tomoyuki Ikeda, Akihiro Komasa, Eiji Tada, Katsuhisa Ishii, Kozo Hotta, Nobuya Higashitani, Toshikazu Jinnai, Yoshihiro Kato, Yasutaka Inuzuka, Chiyo Maeda, Yuko Morikami, Naritatsu Saito, Ryuzo Sakata, Kenji Minatoya, Takeshi Kimura
Whether patients with severe aortic stenosis (AS) die because of AS-related causes is an important issue for the management of these patients. We used data from CURRENT AS registry, a Japanese multicenter registry, to assess the causes of death in severe AS patients and to identify the factors associated with non-cardiac mortality. We enrolled 3815 consecutive patients with a median follow-up of 1176 days; the 1449 overall deaths comprised 802 (55.3%) from cardiac and 647 (44.7%) from non-cardiac causes. Heart failure (HF) (25...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29112562/initiation-of-a-transanal-total-mesorectal-excision-program-at-an-academic-training-program-evaluating-patient-safety-and-quality-outcomes
#16
Justin A Maykel, Uma R Phatak, Pasithorn A Suwanabol, Andrew T Schlussel, Jennifer S Davids, Paul R Sturrock, Karim Alavi
BACKGROUND: Short-term results have shown that transanal total mesorectal excision is safe and effective for patients with mid to low rectal cancers. Transanal total mesorectal excision is considered technically challenging; thus, adoption has been limited to a few academic centers in the United States. OBJECTIVE: The aim of this study is to describe outcomes after the initiation of a transanal total mesorectal excision program in the setting of an academic colorectal training program...
December 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29108336/prognostic-factors-influencing-the-survival-of-patients-with-carcinoma-of-the-gastric-cardia-receiving-preoperative-interventional-embolization-chemotherapy
#17
Hai-Li Cao, Shu-Qiang Jin, Kai-Bing Wang, Bin Bai
The purpose of this study was to analyze the characteristics of patients with gastric cardia cancer (GCC) to identify the main factors the influence the survival rate after interventional embolization chemotherapy (IEC). One hundred and fifty-six patients with advanced GCC were treated with IEC via the left gastric artery. Survival time was defined as from the date of diagnosis until death or the end of this study in June 2015. The median survival time was 15 months (range 3 to 29 months). The Cox proportional hazard model found that patients' age (p < 0...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29103930/superior-mesenteric-artery-calcification-is-associated-with-cardiovascular-risk-factors-systemic-calcified-atherosclerosis-and-increased-mortality
#18
Timothy C Lin, C Michael Wright, Michael H Criqui, Matthew A Allison
BACKGROUND: Atherosclerosis is a major risk factor for morbidity and mortality. However, epidemiologic data are sparse regarding risk factors for superior mesenteric artery calcification (SMAC), the association between SMAC and disease in other arterial beds, or the independent contribution of SMAC to risk of mortality. The objective of this study was to test the hypothesis that presence and extent of SMAC are associated with cardiovascular disease (CVD) risk factors, calcification in other arterial beds, and both cardiovascular and all-cause mortality, independent of classic risk factors and calcification in other arterial beds...
November 2, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29102374/body-composition-is-associated-with-clinical-outcomes-in-patients-with-non-dialysis-dependent-chronic-kidney-disease
#19
Ting-Yun Lin, Ching-Hsiu Peng, Szu-Chun Hung, Der-Cherng Tarng
An inverse relationship between body mass index (BMI) and mortality (the obesity paradox) has been found in patients with non-dialysis-dependent chronic kidney disease (CKD). However, it is unclear whether increased muscle mass or body fat confers the survival advantage. To resolve this we investigated the impact of body makeup on a composite outcome of death or cardiovascular events in a prospective cohort of 326 patients with stage 3-5 CKD not yet on dialysis. Lean mass and body fat were determined using the Body Composition Monitor, a multifrequency bioimpedance spectroscopy device, and were expressed as the lean tissue or fat tissue index, respectively...
November 1, 2017: Kidney International
https://www.readbyqxmd.com/read/29097431/a-simple-algorithm-for-the-identification-of-clinical-copd-phenotypes
#20
Pierre-Régis Burgel, Jean-Louis Paillasseur, Wim Janssens, Jacques Piquet, Gerben Ter Riet, Judith Garcia-Aymerich, Borja Cosio, Per Bakke, Milo A Puhan, Arnulf Langhammer, Inmaculada Alfageme, Pere Almagro, Julio Ancochea, Bartolome R Celli, Ciro Casanova, Juan P de-Torres, Marc Decramer, Andrés Echazarreta, Cristobal Esteban, Rosa Mar Gomez Punter, MeiLan K Han, Ane Johannessen, Bernhard Kaiser, Bernd Lamprecht, Peter Lange, Linda Leivseth, Jose M Marin, Francis Martin, Pablo Martinez-Camblor, Marc Miravitlles, Toru Oga, Ana Sofia Ramírez, Don D Sin, Patricia Sobradillo, Juan J Soler-Cataluña, Alice M Turner, Francisco Javier Verdu Rivera, Joan B Soriano, Nicolas Roche
This study aimed to identify simple rules for allocating chronic obstructive pulmonary disease (COPD) patients to clinical phenotypes identified by cluster analyses.Data from 2409 COPD patients of French/Belgian COPD cohorts were analysed using cluster analysis resulting in the identification of subgroups, for which clinical relevance was determined by comparing 3-year all-cause mortality. Classification and regression trees (CARTs) were used to develop an algorithm for allocating patients to these subgroups...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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