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https://www.readbyqxmd.com/read/27926595/impact-of-skeletal-muscle-mass-index-intramuscular-adipose-tissue-content-and-visceral-to-subcutaneous-adipose-tissue-area-ratio-on-early-mortality-of-living-donor-liver-transplantation
#1
Yuhei Hamaguchi, Toshimi Kaido, Shinya Okumura, Atsushi Kobayashi, Hisaya Shirai, Shintaro Yagi, Naoko Kamo, Hideaki Okajima, Shinji Uemoto
BACKGROUND: Skeletal muscle depletion has been shown to be an independent risk factor for poor survival in various diseases. However, in surgery, the significance of other body components including visceral and subcutaneous adipose tissue remains unclear. METHODS: This retrospective study included 250 adult patients undergoing living donor liver transplantation (LDLT) between January 2008 and April 2015. Using preoperative plain CT imaging at the third lumbar vertebra level, skeletal muscle mass, muscle quality, and visceral adiposity were evaluated by the skeletal muscle mass index (SMI), intramuscular adipose tissue content (IMAC), and visceral to subcutaneous adipose tissue area ratio (VSR), respectively...
December 6, 2016: Transplantation
https://www.readbyqxmd.com/read/27924759/sudden-cardiac-death-in-south-india-incidence-risk-factors-and-pathology
#2
Uma N Srivatsa, K Swaminathan, K Sithy Athiya Munavarah, Ezra Amsterdam, K Shantaraman
BACKGROUND: Sudden cardiac death (SCD) is a major cause of mortality secondary to coronary artery disease (CAD) in the industrialized societies. Although South Asians have a high prevalence of CAD, the frequency and underlying pathology of SCD among this population are unknown. METHODS: Medical records of consecutive patients presenting with unexplained sudden death (USD) in a tertiary care center were reviewed. Patients with trauma, violent deaths, positive toxicology and non-cardiac pathology were excluded to determine sudden cardiac death (SCD)...
July 2016: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/27916380/contemporary-outcomes-of-open-thoracoabdominal-aneurysm-repair-functional-status-is-the-strongest-predictor-of-perioperative-mortality
#3
Tammam Obeid, Caitlin W Hicks, Kanhua Yin, Isibor Arhuidese, Besma Nejim, Arman Kilic, James H Black, Mahmoud Malas
BACKGROUND: Open repair of thoracoabdominal and descending thoracic aneurysm (TAA) carries significant operative morbidity and mortality. Despite evolving operative techniques patient-level risk factors affecting mortality after open TAA repair, including patient functional status, remain to be fully understood. MATERIALS AND METHODS: We identified all open TAA repair cases in the National Surgical Quality Improvement Program database between 2005 and 2013. Multivariable logistic regression was used to evaluate the effect of patients' age, gender, race, body mass index (BMI), comorbid conditions, functional status, ASA class, smoking, rupture, descending thoracic aneurysm versus Crawford types, dissection, and preoperative: transfusion, creatinine levels, on perioperative (30-d) mortality after open TAA repair...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27913235/laparoscopic-gastric-bypass-versus-laparoscopic-sleeve-gastrectomy-a-retrospective-multicenter-comparison-between-early-and-long-term-post-operative-outcomes
#4
Fabio Rondelli, Walter Bugiantella, Maria Cristina Vedovati, Enrico Mariani, Ruben Carlo Balzarotti Canger, Sara Federici, Adriano Guerra, Marcello Boni
BACKGROUND: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most commonly performed procedures for morbid obesity. METHODS: We performed a retrospective review of patients undergoing LRYGB or LSG between August 2000 and November 2014. RESULTS: Data from 581 (280 LSG and 301 LRYGB) were gathered. Operating time (77.6 vs 250.5 min; p < 0.001), post-operative complication rate (3.9% vs 11...
November 29, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27906998/explaining-the-decline-in-coronary-heart-disease-mortality-in-the-netherlands-between-1997-and-2007
#5
Carla Koopman, Ilonca Vaartjes, Ineke van Dis, W M Monique Verschuren, Peter Engelfriet, Edith M Heintjes, Anneke Blokstra, Dorly J H Deeg, Marjolein Visser, Michiel L Bots, Martin O'Flaherty, Simon Capewell
OBJECTIVE: We set out to determine what proportion of the mortality decline from 1997 to 2007 in coronary heart disease (CHD) in the Netherlands could be attributed to advances in medical treatment and to improvements in population-wide cardiovascular risk factors. METHODS: We used the IMPACT-SEC model. Nationwide information was obtained on changes between 1997 and 2007 in the use of 42 treatments and in cardiovascular risk factor levels in adults, aged 25 or over...
2016: PloS One
https://www.readbyqxmd.com/read/27906989/factors-associated-with-cancer-and-non-cancer-related-deaths-among-taiwanese-patients-with-diabetes-after-17-years-of-follow-up
#6
Chin-Hsiao Tseng
OBJECTIVE: A previous 12-year follow-up of a large diabetes cohort in Taiwan suggested a survival advantage in the patients with obesity. The present study further investigated additional determinants for cancer and non-cancer death in the cohort after a follow-up of 17 years. METHODS: A cohort of 92546 diabetes patients recruited since 1995 was followed for vital status by matching the National Death Certificate Database until 2011. Cox regression estimated the hazard ratios for the following variables: age at baseline, sex, diabetes type, screen-detected diabetes (diabetes diagnosed accidentally through epidemiological screening programs or during visits to medical settings without a history of diabetes), diabetes duration, body mass index, insulin use, hypertension, smoking, and living region...
2016: PloS One
https://www.readbyqxmd.com/read/27906837/different-impacts-of-hypertension-and-diabetes-mellitus-on-all-cause-and-cardiovascular-mortality-in-community-dwelling-older-adults-the-rancho-bernardo-study
#7
Jee-Young Oh, Matthew A Allison, Elizabeth Barrett-Connor
OBJECTIVES: Although the prevalence rates of hypertension (HTN) and diabetes mellitus are slowing in some high-income countries, HTN and diabetes mellitus remain as the two major risk factors for atherosclerotic cardiovascular disease (CVD), the leading cause of death in the United States and worldwide. We aimed to observe the association of HTN and diabetes mellitus with all-cause and CVD mortality in older white adults. METHODS: All community-dwelling Rancho Bernardo Study participants who were at least 55 years old and had carefully measured blood pressure and plasma glucose from 75-g oral glucose tolerance test at the baseline visit (1984-1987, n = 2186) were followed up until death or the last clinic visit in 2013 (median 14...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27903539/outcome-implication-of-aortic-valve-area-normalized-to-body-size-in-asymptomatic-aortic-stenosis
#8
Christophe Tribouilloy, Yohann Bohbot, Sylvestre Maréchaux, Nicolas Debry, Quentin Delpierre, Marcel Peltier, Momar Diouf, Michel Slama, David Messika-Zeitoun, Dan Rusinaru
BACKGROUND: Current guidelines define severe aortic stenosis in patients with aortic valve area normalized to body surface area (AVA/BSA) <0.6 cm(2)/m(2); yet, this cutoff has never been validated. Moreover, it is not known whether AVA normalization to other body size indexes allows improved outcome prediction. We aim to test the value of AVA normalized to body size for outcome prediction in asymptomatic aortic stenosis. METHODS AND RESULTS: We included 289 patients with asymptomatic aortic stenosis, preserved ejection fraction, and AVA<1...
November 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27895145/association-between-inflammatory-biomarkers-and-all-cause-cardiovascular-and-cancer-related-mortality
#9
Archana Singh-Manoux, Martin J Shipley, Joshua A Bell, Marianne Canonico, Alexis Elbaz, Mika Kivimäki
BACKGROUND: The inflammatory biomarker α1-acid glycoprotein (AGP) was found to have the strongest association with 5-year mortality in a recent study of 106 biomarkers. We examined whether AGP is a better biomarker of mortality risk than the more widely used inflammatory biomarkers interleukin-6 (IL-6) and C-reactive protein (CRP). METHODS: We analyzed data for 6545 men and women aged 45-69 (mean 55.7) years from the Whitehall II cohort study. We assayed AGP, IL-6 and CRP levels from fasting serum samples collected in 1997-1999...
November 28, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/27892965/diabetes-mellitus-and-risk-of-colorectal-cancer-mortality-in-japan-the-japan-collaborative-cohort-study
#10
Ce Tan, Mitsuru Mori, Yasushi Adachi, Kenji Wakai, Sadao Suzuki, Koji Suzuki, Shuji Hashimoto, Yoshiyuki Watanabe, Akiko Tamakoshi
Objective: Our aim was to estimate whether diabetes mellitus (DM) may be associated with an increased risk of colorectal cancer (CRC) mortality in Japan. Methods: The Japan Collaborative Cohort (JACC) Study is a nationwide prospective study, initiated in 1988, which involves 110,585 subjects (age range: from 40 to 79 years; 46,395 males and 64,190 females). Our present analysis population comprised 96,081 (40,510 men and 55,571 women) who provided details on DM history. The questionnaire also included age, sex, weight, height, family history of CRC, smoking, drinking and exercise habits, and education...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27890886/anemia-in-combined-antiretroviral-treatment-naive-hiv-infected-patients-in-china-a-retrospective-study-of-prevalence-risk-factors-and-mortality
#11
Guorui Dai, Jiang Xiao, Guiju Gao, Xuejing Chong, Fang Wang, Hongyuan Liang, Liang Ni, Di Yang, Fengting Yu, Ling Xu, Di Wang, Junyan Han, Hui Zeng, Hongxin Zhao
Anemia is one of the most important complications of HIV infection. In China, the prevalence, risk factors, and association between anemia and prognosis in HIV-infected patients are poorly elucidated. We analyzed data from 3452 HIV-infected patients not yet on combined antiretroviral therapy (cART) attending Beijing Ditan Hospital from June, 2003 to December, 2015. The overall prevalence of anemia was 9.8% (7.6% mild, 1.9% moderate, and 0.2% severe anemia). Female sex (odds ratio [OR] = 3.71, 95% confidence interval [CI]: 1...
November 26, 2016: Bioscience Trends
https://www.readbyqxmd.com/read/27888288/nonlinear-association-of-bmi-with-all-cause-and-cardiovascular-mortality-in-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-414-587-participants-in-prospective-studies
#12
Francesco Zaccardi, Nafeesa N Dhalwani, Dimitris Papamargaritis, David R Webb, Gavin J Murphy, Melanie J Davies, Kamlesh Khunti
AIMS/HYPOTHESIS: The relationship between BMI and mortality has been extensively investigated in the general population; however, it is less clear in people with type 2 diabetes. We aimed to assess the association of BMI with all-cause and cardiovascular mortality in individuals with type 2 diabetes mellitus. METHODS: We searched electronic databases up to 1 March 2016 for prospective studies reporting associations for three or more BMI groups with all-cause and cardiovascular mortality in individuals with type 2 diabetes mellitus...
November 25, 2016: Diabetologia
https://www.readbyqxmd.com/read/27887863/body-mass-index-and-mortality-in-patients-with-type-2-diabetes-mellitus-a-prospective-cohort-study-of-11-449-participants
#13
Hui Liu, Shouling Wu, Yun Li, Lixia Sun, Zhe Huang, Liming Lin, Yan Liu, Chunpeng Ji, Hualing Zhao, Chunhui Li, Lu Song, Hongliang Cong
AIMS: To investigate the association between body-mass index and mortality in Chinese adults T2DM. METHODS: 11,449 participants of Kailuan Study with T2DM were included in this prospective cohort study. All-cause mortality was calculated using Kaplan-Meier analysis. Cox proportional hazards analysis was used to estimate the association between BMI and mortality. RESULTS: During a mean follow-up period of 7.25±1.42years, 1254 deaths occurred...
October 17, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27884868/combined-associations-of-body-weight-and-lifestyle-factors-with-all-cause-and-cause-specific-mortality-in-men-and-women-prospective-cohort-study
#14
Nicola Veronese, Yanping Li, JoAnn E Manson, Walter C Willett, Luigi Fontana, Frank B Hu
OBJECTIVE:  To evaluate the combined associations of diet, physical activity, moderate alcohol consumption, and smoking with body weight on risk of all cause and cause specific mortality. DESIGN:  Longitudinal study with up to 32 years of follow-up. SETTING:  Nurses' Health Study (1980-2012) and Health Professionals Follow-up Study (1986-2012). PARTICIPANTS:  74 582 women from the Nurses' Health Study and 39 284 men from the Health Professionals Follow-up Study who were free from cardiovascular disease and cancer at baseline...
November 24, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27880070/influence-of-premature-mortality-on-the-link-between-type-2-diabetes-and-hip-fracture-the-fremantle-diabetes-study
#15
Emma Hamilton, Wendy A Davis, David G Bruce, Timothy M E Davis
CONTEXT: Most studies of hip fracture complicating diabetes have used selected patients with incomplete data. None has considered the competing risk of death. OBJECTIVE: To determine influence of the competing risk of death on the association between type 2 diabetes and hip fracture. DESIGN: Longitudinal observational study. SETTING: Urban community. PATIENTS: 1,291 participants with type 2 diabetes (mean±SD age 64...
November 23, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27880050/stable-state-proadrenomedullin-level-in-copd-patients-a-validation-study
#16
Maaike Zuur-Telgen, Paul VanderValk, Job van der Palen, Huib A M Kerstjens, Marjolein Brusse-Keizer
In patients with stable COPD, proadrenomedullin (MR-proADM) has been shown to be a good predictor for mortality. This study aims to provide an external validation of earlier observed cut-off values used by Zuur-Telgen et al. and Stolz.et al. in COPD patients in stable state and at hospitalization for an acute exacerbation of COPD (AECOPD). From the COMIC cohort study we included 545 COPD patients with a blood sample obtained in stable state (n = 490) and/or at hospitalization for an AECOPD (n = 101). Time to death was compared between patients with MR-proADM cut-off scores 0...
November 23, 2016: COPD
https://www.readbyqxmd.com/read/27880044/tuberculosis-airway-obstruction-and-mortality-in-a-finnish-population
#17
Tiina Mattila, Markku Heliövaara, Harri Rissanen, Paul Knekt, Pauli Puukka, Tuula Vasankari
There is little long-term follow-up data concerning the association between past pulmonary tuberculosis (TB), airway obstruction and mortality. We aimed to analyse a national health examination survey data from 6701 adult Finns undergoing spirometry between 1978 and 1980 (follow-up through 2013). We identified TB either through a disease history or by a TB-indicative scar on a chest x-ray. We specified obstruction using the lower limit of normal (LLN) and classified severity using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages 1-4...
November 23, 2016: COPD
https://www.readbyqxmd.com/read/27866759/adherence-to-healthy-lifestyle-factors-and-risk-of-death-in-men-with-diabetes-mellitus-the-physicians-health-study
#18
Yash R Patel, Taraka V Gadiraju, J Michael Gaziano, Luc Djoussé
BACKGROUND & AIMS: The relationship between healthy lifestyle factors and mortality in people with type 2 diabetes is unclear. The purpose of this study was to examine whether healthy lifestyle factors are associated with mortality in people with type 2 diabetes. METHODS: We prospectively studied 1163 men with type 2 diabetes from the Physicians' Health Study. Lifestyle factors consisted of currently not smoking, moderate drinking (1-2 drinks/day), vigorous exercise (1+/week), BMI < 25 kg/m(2), and being in the top 2 quintiles of the alternate healthy eating index-2010 (AHEI-2010)...
November 11, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27866215/impact-of-body-mass-index-on-risk-of-acute-kidney-injury-and-mortality-in-elderly-patients-undergoing-hip-fracture-surgery
#19
A B Pedersen, H Gammelager, J Kahlert, H T Sørensen, C F Christiansen
: The literature is limited regarding risk factors for acute kidney injury (AKI) and mortality in hip fracture patients, although AKI is common in these patients. While obese patients were at increased risk of AKI, underweight patients with and without AKI had elevated mortality for up to 1 year after hip fracture surgery, compared with normal-weight patients. INTRODUCTION: This study aimed to examine risk of postoperative AKI and subsequent mortality, by body mass index (BMI) level, in hip fracture surgery patients aged 65 and over...
November 19, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27849287/effects-of-comprehensive-cardiac-rehabilitation-on-functional-capacity-and-cardiovascular-risk-factors-in-brazilians-assisted-by-public-health-care-protocol-for-a-randomized-controlled-trial
#20
Gabriela S S Chaves, Gabriela L M Ghisi, Sherry L Grace, Paul Oh, Antonio L Ribeiro, Raquel R Britto
Background: Cardiovascular Disease (CVD) is the leading burden of disease worldwide. Moreover, CVD-related death rates are considered an epidemic in low- and middle-income countries (LMICs). Research shows that cardiac rehabilitation (CR) participation reduces death and improves disability and quality of life. Given the growing epidemic of CVD in LMICs and the insufficient evidence about CR programs in these countries, a Randomized Control Trial (RCT) in Latin America is warranted. Objective: To investigate the effects of comprehensive CR on functional capacity and cardiovascular risk factors...
October 27, 2016: Brazilian Journal of Physical Therapy
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