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https://www.readbyqxmd.com/read/28441336/neurobehavioral-outcomes-of-mild-traumatic-brain-injury-a-mini-review
#1
REVIEW
Robert Eme
Traumatic brain injury outcomes can be classified as acute or chronic. Acute outcomes refer to injuries that occur immediately at the time of the injury and subsequent short-term consequences. Chronic outcomes refer to adverse outcomes that are more long-term. In mild traumatic brain injury, recovery from acute outcomes typically occurs very rapidly, i.e., within 2 weeks, with full recovery expected by 90 days. However, some 10%-15% individuals can remain symptomatic for much longer with an outcome termed post-concussive syndrome...
April 25, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28440687/the-consequence-of-spatial-visual-processing-dysfunction-caused-by-traumatic-brain-injury-tbi
#2
William V Padula, Jose E Capo-Aponte, William V Padula, Eric L Singman, Jonathan Jenness
OBJECTIVE: A bi-modal visual processing model is supported by research to affect dysfunction following a traumatic brain injury (TBI). TBI causes dysfunction of visual processing affecting binocularity, spatial orientation, posture and balance. Research demonstrates that prescription of prisms influence the plasticity between spatial visual processing and motor-sensory systems improving visual processing and reducing symptoms following a TBI. RATIONALE: The rationale demonstrates that visual processing underlies the functional aspects of binocularity, balance and posture...
April 25, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28437225/neck-collar-with-mild-jugular-vein-compression-ameliorates-brain-activation-changes-during-a-working-memory-task-after-a-season-of-high-school-football
#3
Weihong Yuan, James Leach, Thomas Maloney, Mekibib Altaye, David Smith, Paul Gubanich, Kim Barber-Foss, Staci Thomas, Christopher DiCesare, Adam Kiefer, Gregory D Myer
Emerging evidence indicates that repetitive head impacts, even at a sub-concussive level, may result in exacerbated or prolonged neurologic deficits in athletes. This study aimed to: 1) quantify the effect of repetitive head impacts on the alteration of neuronal activity based on fMRI of working memory after a high school football season; and 2) determine whether a neck collar that applies mild jugular vein compression to reduce brain energy absorption in head impact through slosh mitigation can ameliorate the altered fMRI activation during a working memory task...
February 18, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28434568/early-return-to-physical-activity-post-concussion-associated-with-reduced-persistent-symptoms
#4
Kathryn J Schneider
No abstract text is available yet for this article.
May 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28431034/effects-of-sleep-loss-on-subjective-complaints-and-objective-neurocognitive-performance-as-measured-by-the-immediate-post-concussion-assessment-and-cognitive-testing
#5
Ryan P J Stocker, Hassen Khan, Luke Henry, Anne Germain
Objective: This study examined the effects of total and partial sleep deprivation on subjective symptoms and objective neurocognitive performance, as measured by the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) in a sample of healthy adults. Method: One-hundred and two, right-handed, healthy participants (between ages 18 and 30 years old) completed three consecutive nights in the sleep laboratory with concurrent continuous polysomnography monitoring...
May 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28431031/sandbagging-on-the-immediate-post-concussion-assessment-and-cognitive-testing-impact-in-a-high-school-athlete-population
#6
Kathryn L Higgins, Robert L Denney, Arthur Maerlender
The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a computerized neuropsychological test battery commonly used to assess cognitive functioning after a concussion. It is recommended that application of ImPACT utilizes a baseline administration so athletes have an individualized baseline with which to compare post-injury results should they sustain a concussion. It has been suggested that athletes may provide suboptimal effort, called "sandbagging," in order to return to their baseline cognitive scores, and thus to play, more quickly...
May 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28414250/longitudinal-changes-in-brain-morphology-from-4-weeks-to-12-months-after-mild-traumatic-brain-injury-associations-with-cognitive-functions-and-clinical-variables
#7
T Hellstrom, L T Westlye, S Sigurdardottir, C Brunborg, H L Soberg, Ø Holthe, A Server, M J Lund, O A Andreassen, N Andelic
OBJECTIVE: To investigate longitudinal changes in cortical and subcortical volumes in patients with mild traumatic brain injury (MTBI) and to evaluate whether such changes were associated with self-reported post-concussive symptoms, global functional outcomes and neuropsychological functioning. METHODS: This was a prospecitve, longitudinal cohort study of patients with complicated (i.e presence of intracranial abnormalities on the day of injury CT) and uncomplicated MTBI (i...
April 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28412305/memantine-improves-outcomes-after-repetitive-traumatic-brain-injury
#8
Zhengrong Mei, Jianhua Qiu, Sasha Alcon, Jumana Hashim, Alexander Rotenberg, Yan Sun, William P Meehan, Rebekah Mannix
Repetitive mild traumatic brain injury (rmTBI; e.g., sports concussions) is common and results in significant cognitive impairment. Targeted therapies for rmTBI are lacking, though evidence from other injury models indicates that targeting N-methyl-d-aspartate (NMDA) receptor (NMDAR)-mediated glutamatergic toxicity might mitigate rmTBI-induced neurologic deficits. However, there is a paucity of preclinical or clinical data regarding NMDAR antagonist efficacy in the rmTBI setting. To test whether NMDAR antagonist therapy improves outcomes after rmTBI, mice were subjected to rmTBI injury (4 injuries in 4 days) and randomized to treatment with the NMDA antagonist memantine or with vehicle...
April 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28412141/toll-like-receptor-4-activation-can-be-either-detrimental-or-beneficial-following-mild-repetitive-traumatic-brain-injury-depending-on-timing-of-activation
#9
Frances Corrigan, Alina Arulsamy, Lyndsey E Collins-Praino, Joshua L Holmes, Robert Vink
A history of repeated concussion has been linked to the later development of neurodegeneration, which is associated with the accumulation of hyperphosphorylated tau and the development of behavioral deficits. However, the role that exogenous factors, such as immune activation, may play in the development of neurodegeneration following repeated mild traumatic brain injury (rmTBI) has not yet been explored. To investigate, male Sprague-Dawley rats were administered three mTBIs 5 days apart using the diffuse impact-acceleration model to generate ∼100G...
April 13, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28409514/neck-strength-and-self-reported-neck-dysfunction-what-is-the-impact-of-a-season-of-rugby-union
#10
Danielle M Salmon, S John Sullivan, Phil Handcock, Nancy J Rehrer, Brian Niven
BACKGROUND: Neck strength has been reported to reduce the incidence of concussions and neck injuries. However little is known about how neck strength changes over a playing season. AIM: To understand the impact a 20-week rugby season has on neck strength, neck pain (NP) and neck stiffness (NS) in a cohort of rugby players, relative to a non-contact control group. METHODS: This prospective cohort study employed a fixed-frame dynamometer to measure neck strength in a simulated contact posture in rugby players (n=32) and controls (n=15)...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28400221/validation-of-a-self-monitoring-tool-for-use-in-exercise-therapy
#11
Camilla S Powierza, Michael D Clark, Jaime M Hughes, Kevin A Carneiro, Jason P Mihalik
BACKGROUND: Aerobic exercise at a sub-symptom heart rate has been recommended as therapy for Post-Concussion Syndrome (PCS). Assessing adherence with an accurate heart rate monitoring instrument is difficult limiting the proliferation of large-scale randomized controlled trials. OBJECTIVE: To evaluate the validity of the Fitbit Charge HR against electrocardiogram (EKG) to monitor heart rate during a treadmill-based exercise protocol. DESIGN: A methods comparison study...
April 8, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28399158/mild-traumatic-brain-injury-mtbi-and-chronic-cognitive-impairment-a-scoping-review
#12
Kerry McInnes, Christopher L Friesen, Diane E MacKenzie, David A Westwood, Shaun G Boe
Mild traumatic brain injury (mTBI), or concussion, is the most common type of traumatic brain injury. With mTBI comes symptoms that include headaches, fatigue, depression, anxiety and irritability, as well as impaired cognitive function. Symptom resolution is thought to occur within 3 months post-injury, with the exception of a small percentage of individuals who are said to experience persistent post-concussion syndrome. The number of individuals who experience persistent symptoms appears to be low despite clear evidence of longer-term pathophysiological changes resulting from mTBI...
2017: PloS One
https://www.readbyqxmd.com/read/28398160/should-young-children-with-tbi-be-compared-to-community-or-orthopedic-control-participants
#13
Miriam Helen Beauchamp, Catherine Landry-Roy, Jocelyn Gravel, Cindy Beaudoin, Annie Bernier
Pediatric traumatic brain injury (TBI) research depends on comparisons of profiles and outcome between brain injured individuals and groups consisting either of injured controls (e.g., orthopedic injuries, OI) or uninjured, typically developing children recruited from the community (community controls, CC). Children with OI are thought to provide optimal comparisons for individuals with TBI because they share injury-related experiences and pre-morbid characteristics; however, a study by Mathias and colleagues (2013) in adults has called into question the added value of injury control groups in TBI research...
April 11, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28397546/measuring-cognitive-change-with-impact-the-aggregate-baseline-approach
#14
Jared M Bruce, Ruben J Echemendia, Willem Meeuwisse, Michael G Hutchison, Mark Aubry, Paul Comper
OBJECTIVE: The Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) is commonly used to assess baseline and post-injury cognition among athletes in North America. Despite this, several studies have questioned the reliability of ImPACT when given at intervals employed in clinical practice. Poor test-retest reliability reduces test sensitivity to cognitive decline, increasing the likelihood that concussed athletes will be returned to play prematurely. We recently showed that the reliability of ImPACT can be increased when using a new composite structure and the aggregate of two baselines to predict subsequent performance...
April 11, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28393012/the-effect-of-repetitive-subconcussive-collisions-on-brain-integrity-in-collegiate-football-players-over-a-single-football-season-a-multi-modal-neuroimaging-study
#15
Semyon M Slobounov, Alexa Walter, Hans C Breiter, David C Zhu, Xiaoxiao Bai, Tim Bream, Peter Seidenberg, Xianglun Mao, Brian Johnson, Thomas M Talavage
The cumulative effect of repetitive subconcussive collisions on the structural and functional integrity of the brain remains largely unknown. Athletes in collision sports, like football, experience a large number of impacts across a single season of play. The majority of these impacts, however, are generally overlooked, and their long-term consequences remain poorly understood. This study sought to examine the effects of repetitive collisions across a single competitive season in NCAA Football Bowl Subdivision athletes using advanced neuroimaging approaches...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28387693/visual-vestibular-processing-deficits-in-mild-traumatic-brain-injury
#16
W G Wright, R T Tierney, J McDevitt
BACKGROUND: The search for reliable and valid signs and symptoms of mild traumatic brain injury (mTBI), commonly synonymous with concussion, has lead to a growing body of evidence that individuals with long-lasting, unremitting impairments often experience visual and vestibular symptoms, such as dizziness, postural and gait disturbances. OBJECTIVE: Investigate the role of visual-vestibular processing deficits following concussion. METHODS: A number of clinically accepted vestibular, oculomotor, and balance assessments as well as a novel virtual reality (VR)-based balance assessment device were used to assess adults with post-acute concussion (n = 14) in comparison to a healthy age-matched cohort (n = 58)...
2017: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/28387551/evaluation-of-nintendo-wii-balance-board-as-a-tool-for-measuring-postural-stability-after-sport-related-concussion
#17
Kian Merchant-Borna, Courtney Marie Cora Jones, Mattia Janigro, Erin B Wasserman, Ross A Clark, Jeffrey J Bazarian
CONTEXT: Recent changes to postconcussion guidelines indicate that postural-stability assessment may augment traditional neurocognitive testing when making return-to-participation decisions. The Balance Error Scoring System (BESS) has been proposed as 1 measure of balance assessment. A new, freely available software program to accompany the Nintendo Wii Balance Board (WBB) system has recently been developed but has not been tested in concussed patients. OBJECTIVE: To evaluate the feasibility of using the WBB to assess postural stability across 3 time points (baseline and postconcussion days 3 and 7) and to assess concurrent and convergent validity of the WBB with other traditional measures (BESS and Immediate Post-Concussion Assessment and Cognitive Test [ImPACT] battery) of assessing concussion recovery...
March 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28385102/introduction-of-the-abbreviated-westmead-post-traumatic-amnesia-scale-and-impact-on-length-of-stay
#18
C E Watson, E A Clous, M Jaeger, S K D'Amours
BACKGROUND AND AIMS: Mild traumatic brain injury is a common presentation to Emergency Departments. Early identification of patients with cognitive deficits and provision of discharge advice are important. The Abbreviated Westmead Post-traumatic Amnesia Scale provides an early and efficient assessment of post-traumatic amnesia for patients with mild traumatic brain injuries, compared with the previously used assessment, the Modified Oxford Post-traumatic Scale. MATERIAL AND METHODS: This retrospective cohort study reviewed 270 patients with mild traumatic brain injury assessed for post-traumatic amnesia over a 2-year period between February 2011 and February 2013...
April 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/28384609/dual-task-gait-differences-in-female-and-male-adolescents-following-sport-related-concussion
#19
David R Howell, Andrea Stracciolini, Ellen Geminiani, William P Meehan
Concussion may affect females and males differentially. Identification of gender-related differences after concussion, therefore, may help clinicians with individualized evaluations. We examined potential differences in dual-task gait between females and males after concussion. Thirty-five participants diagnosed with a concussion (49% female, mean age=15.0±2.1 years, 7.5±3.0 days post-injury) and 51 controls (51% female, mean age=14.4±2.1 years) completed a symptom inventory and single/dual-task gait assessment...
April 1, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28372513/economic-evaluation-of-telephone-based-concussion-management-for-combat-related-mild-traumatic-brain-injury
#20
John S Richardson, Gregory F Guzauskas, Jesse R Fann, Nancy R Temkin, Nigel E Bush, Kathleen R Bell, Gregory A Gahm, Derek J Smolenski, Jo Ann Brockway, Ryan N Hansen
Introduction Mild traumatic brain injury (mTBI) is an unfortunately common repercussion of military service in a combat zone. The CONTACT study tested an individualized telephone support intervention employing problem solving therapy (PST) for mTBI in soldiers recently returned from deployment. We sought to determine the cost effectiveness of this intervention from a military healthcare system perspective. Methods We conducted an intent-to-treat post-hoc analysis by building a decision analytic model that evaluated the choice between using PST or education only (EO)...
January 1, 2017: Journal of Telemedicine and Telecare
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