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https://www.readbyqxmd.com/read/28211600/feasibility-of-early-physical-therapy-for-dizziness-after-a-sports-related-concussion-a-randomized-clinical-trial
#1
J C Reneker, A Hassen, R S Phillips, M C Moughiman, M Donaldson, J Moughiman
The purpose of this study was to (a) assess the feasibility of recruitment/retention of participants, protocol/resource management, and participant safety, and (b) estimate the size of the effect between the experimental and control groups. This was a feasibility study conducted as a prospective pilot double-blind randomized clinical trial. Subjects aged 10-23 years old with acute concussion and dizziness were enrolled from sports medicine centers. Forty-one participants were randomized into treatment and were seen for physical therapy beginning at 10 days post-concussion...
February 17, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28205009/mixed-pathologies-including-chronic-traumatic-encephalopathy-account-for-dementia-in-retired-association-football-soccer-players
#2
Helen Ling, Huw R Morris, James W Neal, Andrew J Lees, John Hardy, Janice L Holton, Tamas Revesz, David D R Williams
In retired professional association football (soccer) players with a past history of repetitive head impacts, chronic traumatic encephalopathy (CTE) is a potential neurodegenerative cause of dementia and motor impairments. From 1980 to 2010, 14 retired footballers with dementia were followed up regularly until death. Their clinical data, playing career, and concussion history were prospectively collected. Next-of-kin provided consent for six to have post-mortem brain examination. Of the 14 male participants, 13 were professional and 1 was a committed amateur...
February 15, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28192036/using-acute-performance-on-a-comprehensive-neurocognitive-vestibular-and-ocular-motor-assessment-battery-to-predict-recovery-duration-after-sport-related-concussions
#3
Alicia M Sufrinko, Gregory F Marchetti, Paul E Cohen, R J Elbin, Valentina Re, Anthony P Kontos
BACKGROUND: A sport-related concussion (SRC) is a heterogeneous injury that requires a multifaceted and comprehensive approach for diagnosis and management, including symptom reports, vestibular/ocular motor assessments, and neurocognitive testing. PURPOSE: To determine which acute (eg, within 7 days) vestibular, ocular motor, neurocognitive, and symptom impairments predict the duration of recovery after an SRC. STUDY DESIGN: Cohort study (prognosis); Level of evidence, 2...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28188778/work-limitations-four-years-following-mild-traumatic-brain-injury-a-cohort-study
#4
Alice Theadom, Suzanne Barker-Collo, Kelly Jones, Michael Kahan, Braden Te Ao, Kathryn McPherson, Nicola Starkey, Valery Feigin
OBJECTIVE: To explore employment status, work limitations and productivity loss following mild traumatic brain injury (TBI). STUDY DESIGN: Inception cohort study over four years. SETTING: General community. PARTICIPANTS: 245 Adults (>16 years at the time of injury), who experienced a mild TBI and who were employed prior to their injury. INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: Details of the injury, demographic information and pre-injury employment status were collected from medical records and self-report...
February 7, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28170134/mild-traumatic-brain-injury-is-something-missing-when-comparing-cognitive-rest-and-graduated-return-to-usual-activities-versus-usual-care
#5
Vaitsa Giannouli
I read with great interest the article by Varner et al.(1) which aims to determine in a simple, concise, and neat way if mild traumatic brain injury (MTBI) patients randomized to graduated return to usual activity discharge instructions have a decrease in their Post Concussion Symptom Score (PCSS) two weeks after MTBI, compared to patients who receive usual care MTBI discharge instructions. This article is protected by copyright. All rights reserved.
February 7, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28170122/utility-of-serum-biomarkers-in-the-diagnosis-and-stratification-of-mild-traumatic-brain-injury
#6
Lawrence M Lewis, Derek Schloemann, Linda Papa, Robert Fucetola, Jeffrey Bazarian, Miranda Lindburg, Robert Welch
OBJECTIVE: To compare test characteristics of a single serum concentration of glial fibrillary acidic protein (GFAP), S-100β, and ubiquitin carboxyl terminal hydrolase L1 (UCH-L1), obtained within 6 hours of head injury, to diagnose mild traumatic brain injury (mTBI) in head-injured subjects. METHODS: Adults aged 18-80 who presented to one of seven EDs with a blunt closed head injury, underwent head CT within 4 hours of injury, and had blood drawn for biomarker analysis within 6 hours of injury were eligible...
February 7, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28169147/single-task-and-dual-task-tandem-gait-test-performance-after-concussion
#7
David R Howell, Louis R Osternig, Li-Shan Chou
OBJECTIVES: To compare single-task and dual-task tandem gait test performance between athletes after concussion with controls on observer-timed, spatio-temporal, and center-of-mass (COM) balance control measurements. DESIGN: Ten participants (19.0±5.5years) were prospectively identified and completed a tandem gait test protocol within 72h of concussion and again 1 week, 2 weeks, 1 month, and 2 months post-injury. Seven uninjured controls (20.0±4.5years) completed the same protocol in similar time increments...
January 24, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28167303/psychological-and-lifestyle-factors-that-influence-the-serial-reporting-of-post-concussive-like-symptoms-in-a-non-concussed-population
#8
Arun Prasad Balasundaram, Josie Athens, Anthony Gerard Schneiders, Paul McCrory, Stephen John Sullivan
BACKGROUND: Symptoms related to concussion are generally found to be non-specific in nature as they are also reported by non-concussed individuals. What is currently not known is whether the symptoms vary over time, and whether they are also influenced by a multitude of factors. OBJECTIVE: To investigate the potential influence of psychological, lifestyle, and situational factors on the change in postconcussion-like symptoms reported over seven consecutive days in a cohort of normal individuals...
February 3, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28162097/is-age-associated-with-the-severity-of-post-mild-traumatic-brain-injury-symptoms
#9
Tina Hu, Cindy Hunt, Donna Ouchterlony
BACKGROUND: Mild traumatic brain injury (mTBI) is a significant public health concern. Research has shown that mTBI is associated with persistent physical, cognitive, and behavioural symptoms, leading to significant direct and indirect medical costs. Our objective was to determine if age impacts the type and severity of post-mTBI symptoms experienced. METHODS: Retrospective analysis of prospectively collected data at a level 1 tertiary care outpatient head injury clinic...
February 6, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28159872/utilization-of-mental-health-services-after-mild-pediatric-traumatic-brain-injury
#10
Nathalia Jimenez, Alex Quistberg, Monica S Vavilala, Kenneth M Jaffe, Frederick P Rivara
BACKGROUND: Mild traumatic brain injury injuries (mTBIs), including concussions, represent >2 million US pediatric emergency department visits annually. Post-mTBI mental health symptoms are prominent and often attributed to the mTBI. This study examined whether individuals seeking post-mTBI mental health care had previous mental health diagnoses or a new onset of such disorders, and determined if mental health care utilization differed by race/ethnicity. METHODS: Retrospective cohort study, using the Medicaid Marketscan claims national dataset (2007-2012)...
February 3, 2017: Pediatrics
https://www.readbyqxmd.com/read/28153668/prevalence-of-hearing-loss-and-tinnitus-in-iraq-and-afghanistan-veterans-a-chronic-effects-of-neurotrauma-consortium-study
#11
A A Swan, J T Nelson, B Swiger, C A Jaramillo, B C Eapen, M Packer, M J Pugh
The purpose of this study was to describe the prevalence of hearing loss and tinnitus in a cohort of Iraq and Afghanistan Veterans (IAV) with common post-deployment conditions, including traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and other typical post-concussive conditions such as headaches and vertigo/dizziness. This retrospective observational study used data from the national Veterans Health Administration (VA) data repository from fiscal years 2001-2014. Veteran data was included if there were at least three years of VA care, with one or more years of care in 2007 or after...
January 31, 2017: Hearing Research
https://www.readbyqxmd.com/read/28144218/changes-in-cortical-plasticity-in-relation-to-a-history-of-concussion-during-adolescence
#12
Sean K Meehan, Jasmine L Mirdamadi, Douglas N Martini, Steven P Broglio
Adolescence and early adulthood is a critical period for neurophysiological development potentially characterized by an increased susceptibility to the long-term effects of traumatic brain injury. The current study investigated differences in motor cortical physiology and neuroplastic potential across a cohort of young adults with adolescent concussion history and those without. Transcranial magnetic stimulation (TMS) was used to assess motor evoked potential (MEP) amplitude, short-interval cortical inhibition (SICI) and intracortical facilitation (ICF) before and after intermittent theta burst stimulation (iTBS)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28128703/a-comparison-in-a-youth-population-between-those-with-and-without-a-history-of-concussion-using-biomechanical-reconstruction
#13
Andrew Post, T Blaine Hoshizaki, Michael D Gilchrist, David Koncan, Lauren Dawson, Wesley Chen, Andrée-Anne Ledoux, Roger Zemek
OBJECTIVE Concussion is a common topic of research as a result of the short- and long-term effects it can have on the affected individual. Of particular interest is whether previous concussions can lead to a biomechanical susceptibility, or vulnerability, to incurring further head injuries, particularly for youth populations. The purpose of this research was to compare the impact biomechanics of a concussive event in terms of acceleration and brain strains of 2 groups of youths: those who had incurred a previous concussion and those who had not...
January 27, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28125932/brief-cognitive-behavioral-intervention-for-children-and-adolescents-with-persistent-post-concussive-symptoms-a-pilot-study
#14
Kelly A McNally, Kristina E Patrick, Jacob E LaFleur, Jana B Dykstra, Kerry Monahan, Kristen R Hoskinson
This study aims to evaluate the efficacy of a brief cognitive behavioral intervention program for children and adolescents experiencing persistent post-concussion symptoms. A total of 31 patients aged 10 to 18 years participated in the intervention. The median time since injury at treatment onset was 95 days though the range was large (23-720 days). Treatment was on average four sessions in duration. Sessions included concussion education, activity scheduling, sleep hygiene relaxation training, and cognitive restructuring...
January 26, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28124982/overview-of-traumatic-brain-injury-an-immunological-context
#15
REVIEW
Damir Nizamutdinov, Lee A Shapiro
Traumatic brain injury (TBI) afflicts people of all ages and genders, and the severity of injury ranges from concussion/mild TBI to severe TBI. Across all spectrums, TBI has wide-ranging, and variable symptomology and outcomes. Treatment options are lacking for the early neuropathology associated with TBIs and for the chronic neuropathological and neurobehavioral deficits. Inflammation and neuroinflammation appear to be major mediators of TBI outcomes. These systems are being intensively studies using animal models and human translational studies, in the hopes of understanding the mechanisms of TBI, and developing therapeutic strategies to improve the outcomes of the millions of people impacted by TBIs each year...
January 23, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28122770/factor-structure-of-impact%C3%A2-in-adolescent-student-athletes
#16
Paul B Gerrard, Grant L Iverson, Joseph E Atkins, Bruce A Maxwell, Ross Zafonte, Philip Schatz, Paul D Berkner
OBJECTIVE: ImPACT(®) (Immediate Post-Concussion Assessment and Cognitive Testing) is a computerized neuropsychological screening battery, which is widely used to measure the acute effects of sport-related concussion and to monitor recovery from injury. This study examined the factor structure of ImPACT(®) in several samples of high school student athletes. We hypothesized that a 2-factor structure would be present in all samples. METHOD: A sample of 4,809 adolescent student athletes was included, and subgroups with a history of treatment for headaches or a self-reported history of learning problems or attention-deficit hyperactivity disorder were analyzed separately...
February 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28119303/effects-of-sleep-loss-on-subjective-complaints-and-objective-neurocognitive-performance-as-measured-by-the-immediate-post-concussion-assessment-and-cognitive-testing
#17
Ryan P J Stocker, Hassen Khan, Luke Henry, Anne Germain
OBJECTIVE: This study examined the effects of total and partial sleep deprivation on subjective symptoms and objective neurocognitive performance, as measured by the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) in a sample of healthy adults. METHOD: One-hundred and two, right-handed, healthy participants (between ages 18 and 30 years old) completed three consecutive nights in the sleep laboratory with concurrent continuous polysomnography monitoring...
January 23, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28117263/plasma-micro-rna-biomarkers-for-diagnosis-and-prognosis-after-traumatic-brain-injury-a-pilot-study
#18
Biswadev Mitra, Thomas F Rau, Nanda Surendran, James H Brennan, Prasanthan Thaveenthiran, Edmond Sorich, Mark C Fitzgerald, Jeffrey V Rosenfeld, Sarjubhai A Patel
Prediction of post-concussive syndrome after apparent mild traumatic brain injury (TBI) and subsequent cognitive recovery remains challenging, with substantial limitations of current methods of cognitive testing. This pilot study aimed to determine if levels of micro ribonucleic acids (RNAs) circulating in plasma are altered following TBI, and if changes to levels of such biomarkers over time could assist in determination of prognosis after TBI. Patients were enrolled after TBI on presentation to the Emergency Department and allocated to three groups: A - TBI (physical trauma to the head), witnessed loss of consciousness, amnesia, GCS=15, a normal CT Brain and a recorded first pass after post-traumatic amnesia (PTA) scale; B TBI, witnessed LOC, amnesia, GCS=15, a normal CT brain and a PTA scale test fail and: C - TBI and initial GCS <13 on arrival to the ED...
January 20, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28107556/do-post-concussion-like-symptom-responses-change-following-exercise-or-sports-participation-in-a-non-concussed-cohort
#19
Arun Prasad Balasundaram, Josie Athens, Anthony G Schneiders, Paul McCrory, S John Sullivan
The purpose of this study were; 1) To determine the reliable change in post concussion-like symptoms reported following self-selected exercise or sports activities. 2) To explore the potential influence of gender and exercise parameters on post concussion-like symptoms reported by a non-concussed cohort following exercise/training. A pre-post observational design was used. A convenience sample of students aged 18-30 years who visited a university recreation centre to engage in their chosen exercise activity, and a purposeful sample of men's and women's rugby union players engaged in their regular training sessions...
January 20, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28103876/the-norwegian-version-of-the-qolibri-a-study-of-metric-properties-based-on-a-12%C3%A2-month-follow-up-of-persons-with-traumatic-brain-injury
#20
Helene Lundgaard Soberg, Cecilie Roe, Cathrine Brunborg, Nicole von Steinbüchel, Nada Andelic
BACKGROUND: Consequences after Traumatic brain injury (TBI) affect the injured person's self-image and quality of life. The purpose was to assess the health related quality of life (HRQoL) at 12 months after a TBI in patients admitted to regional trauma centres, and to evaluate the metric properties of the Norwegian version of the Quality of Life After Brain Injury (QOLIBRI) questionnaire. METHODS: Two hundred four patients with TBI of all severities were included...
January 19, 2017: Health and Quality of Life Outcomes
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