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Endocarditis

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https://www.readbyqxmd.com/read/29691140/interaction-between-the-staphylococcus-aureus-extracellular-adherence-protein-eap-and-its-subdomains-with-platelets
#1
Raghavendra Palankar, Ulrike Binsker, Bianca Haracska, Jan Wesche, Andreas Greinacher, Sven Hammerschmidt
S. aureus associated bacteremia can lead to severe infections with high risk of mortality (e.g. sepsis, infective endocarditis). Many virulence factors and adhesins of S. aureus are known to directly interact with platelets. Extracellular adherence protein, Eap, one of the most important virulence factors in S. aureus mediated infections is a multi-tandem domain protein and has been shown to interact with almost all cell types in the human circulatory system. By using amine reactive fluorescent N-hydroxysuccinimidyl (NHS)-ester dyes and by direct detection with primary fluorescently conjugated anti-histidine (His-tag) antibodies against detect N-terminal His6, we show Eap subdomain Eap D3 D4 specifically interacts and rapidly activates human platelets...
April 18, 2018: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/29688284/reply-to-author
#2
Juan Ambrosioni, Xabier Urra, Jaume Llopis, Asuncion Moreno, Angel Chamorro, José M Miró
No abstract text is available yet for this article.
April 24, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29688145/use-of-echocardiography-at-diagnosis-and-detection-of-acute-cardiac-disease-in-youth-with-systemic-lupus-erythematosus
#3
J C Chang, A M Knight, R Xiao, L M Mercer-Rosa, P F Weiss
Objectives There are no guidelines on the use of echocardiography to detect cardiac manifestations of childhood-onset systemic lupus erythematosus (SLE). We quantify the prevalence of acute cardiac disease in youth with SLE, describe echocardiogram utilization at SLE diagnosis, and compare regional echocardiogram use with incident cardiac diagnoses. Methods Using the Clinformatics® DataMart (OptumInsight, Eden Prairie, MN) de-identified United States administrative database from 2000 to 2013, we identified youth ages 5-24 years with new-onset SLE (≥3 ICD-9 SLE codes 710...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29686711/infective-endocarditis-in-a-young-adult-due-to-lactococcus-lactis-a-case-report-and-review-of-the-literature
#4
G Georgountzos, C Michopoulos, C Grivokostopoulos, M Kolosaka, N Vlassopoulou, A Lekkou
Infective endocarditis (IE) is a condition mainly associated with valvular disease or prosthetic valve and intravenous drug use as a risk factor. Here, we describe a rare case of a previously healthy patient with endocarditis due to Lactococcus lactis associated with cattle contact, where antibiotic treatment resulted in full recovery.
2018: Case Reports in Medicine
https://www.readbyqxmd.com/read/29686571/-bartonella-endocarditis-with-glomerulonephritis-in-a-patient-with-complete-transposition-of-the-great-arteries
#5
Helen Hashemi, Tiana R Endicott-Yazdani, Christopher Oguayo, David M Harmon, Tuan Tran, Ginger Tsai-Nguyen, Raul Benavides, Cedric W Spak, Hoang-Lan Nguyen
We describe a patient with history of dextro-transposition of the great vessels, ventricular septal defect, and pulmonary valve replacement who presented with fatigue, prolonged fever, and leg edema. He was found to have kidney injury, pancytopenia, and liver congestion. Echocardiogram revealed thickened leaflets with prolapsing vegetation on the pulmonary valve. Given the negative blood cultures, high Bartonella henselae immunogobulin G titer (≥1:1024) and positive immunoglobulin M titer (≥1:20), he was diagnosed with Bartonella endocarditis complicated with glomerulonephritis...
January 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29685924/the-clot-thickens-an-incompletely-ligated-left-atrial-appendage
#6
Merrill Thomas, Anna Grodzinsky, Martin Zink
Our patient presented with known mechanical mitral valve endocarditis documented by 2D transesophageal echocardiogram (TOE) from a recent hospitalization at an outside facility. On admission to our center, there was no prior knowledge of an incompletely ligated left atrial appendage including by patient- or family-reported history, review of outside records, or the outside 2D TOE report. A 3D TOE performed at our center to assess her pathology, since a month had passed from her prior hospitalization, revealed a left atrial appendage (LAA) ligation with evidence of communication to the left atrium and with clot present in the appendage...
April 23, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29685511/primary-and-secondary-arterial-fistulas-during-chronic-q-fever
#7
Steffi Karhof, Sonja E van Roeden, Jan J Oosterheert, Chantal P Bleeker-Rovers, Nicole H M Renders, Gert J de Borst, Linda M Kampschreur, Andy I M Hoepelman, Olivier H J Koning, Peter C Wever
OBJECTIVE: After primary infection with Coxiella burnetii, patients may develop acute Q fever, which is a relatively mild disease. A small proportion of patients (1%-5%) develop chronic Q fever, which is accompanied by high mortality and can be manifested as infected arterial or aortic aneurysms or infected vascular prostheses. The disease can be complicated by arterial fistulas, which are often fatal if they are left untreated. We aimed to assess the cumulative incidence of arterial fistulas and mortality in patients with proven chronic Q fever...
April 20, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29685477/hallmark-cutaneous-signs-of-infective-endocarditis
#8
Fred Bernardes Filho, Caio Cavalcante Machado, Rodolfo Mendes Queiroz, Breno Nery
No abstract text is available yet for this article.
April 20, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29680174/human-serum-albumin-in-cardiovascular-diseases
#9
REVIEW
Stephane Arques
Cardiovascular diseases are the leading cause of death worldwide. Endothelial dysfunction, inflammation and oxidative stress are at the forefront in the onset and development of atherosclerosis and many cardiovascular diseases. Epidemiological evidence is that low serum albumin levels are linked to incident ischemic heart disease, heart failure, atrial fibrillation, stroke and venous thromboembolism, independent of risk factors, body mass index and inflammation. Hypoalbuminemia has also emerged as an independent prognosticator in many cardiovascular diseases, such as coronary artery disease, heart failure, congenital heart disease, infective endocarditis and stroke, even after adjusting for usual causal factors and prognostic markers...
April 18, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29674326/risk-of-infective-endocarditis-after-invasive-dental-treatments-a-case-only-study
#10
Tzu-Ting Chen, Yi-Chun Yeh, Kuo-Liong Chien, Mei-Shu Lai, Yu-Kang Tu
Background -Invasive dental treatments (IDTs) can yield temporary bacteremia and has therefore been considered a potential risk factor of infective endocarditis (IE). It is hypothesized that, through the trauma caused by IDTs, bacteria gain entry to the bloodstream and may attach to abnormal heart valves or damaged heart tissue, giving rise to IE. However, the association between IDTs and IE remains controversial. The aim of this study is to estimate the association between IDTs and IE. Methods -The data in this study were obtained from the Health Insurance Database in Taiwan...
April 19, 2018: Circulation
https://www.readbyqxmd.com/read/29673380/a-standardized-approach-to-treat-complex-aortic-valve-endocarditis-a-case-series
#11
Anna Gomes, Jayant S Jainandunsing, Sander van Assen, Peter Paul van Geel, Bhanu Sinha, Sandro Gelsomino, Daniel M Johnson, Ehsan Natour
BACKGROUND: Surgical treatment of complicated aortic valve endocarditis often is challenging, even for experienced surgeons. We aim at demonstrating a standardized surgical approach by stentless bioprostheses for the treatment of aortic valve endocarditis complicated by paravalvular abscess formation. METHODS: Sixteen patients presenting with aortic valve endocarditis (4 native and 12 prosthetic valves) and paravalvular abscess formation at various localizations and to different extents were treated by a standardized approach using stentless bioprostheses...
April 19, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29672631/correction-outcome-of-enterococcus-faecalis-infective-endocarditis-according-to-the-length-of-antibiotic-therapy-preliminary-data-from-a-cohort-of-78-patients
#12
Juan M Pericàs, Carlos Cervera, Asunción Moreno, Cristina Garcia-de-la-Mària, Manel Almela, Carles Falces, Eduard Quintana, Bàrbara Vidal, Jaume Llopis, David Fuster, Carlos A Mestres, Francesc Marco, Jose M Miró
[This corrects the article DOI: 10.1371/journal.pone.0192387.].
2018: PloS One
https://www.readbyqxmd.com/read/29671174/increased-overall-survival-after-introduction-of-structured-bedside-consultation-in-staphylococcus-aureus-bacteraemia
#13
Maud B P A Ariaans, Elisabeth A Roovers, Mark A A Claassen, Robert-Jan Hassing, Caroline M A Swanink, Elisabeth H Gisolf
Staphylococcus aureus bacteraemia (SAB) is a common and severe disease. In 2012, a structured bedside consultation (SBC) was introduced at Rijnstate Hospital. We analysed the effect of this SBC on the overall survival of patients with SAB and the effect on the diagnostic workup. We performed a retrospective cohort study, including all patients over 18 years with SAB from 2009 until 2017. The cases preceding versus those after implementation of SBC in 2012 were compared. In total, 613 episodes of SAB were analysed: 234 cases before and 379 cases since SBC...
April 18, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29670602/human-genetic-susceptibility-to-native-valve-staphylococcus-aureus-endocarditis-in-patients-with-s-aureus-bacteremia-genome-wide-association-study
#14
Karen Moreau, Alisson Clemenceau, Vincent Le Moing, David Messika-Zeitoun, Paal S Andersen, Niels E Bruun, Robert L Skov, Florence Couzon, Coralie Bouchiat, Marie L Erpelding, Alex van Belkum, Yohan Bossé, Xavier Duval, Francois Vandenesch
Staphylococcus aureus infective endocarditis (SaIE) is a severe complication of S. aureus bacteremia (SAB) occurring in up to 22% of patients. Bacterial genetic factors and host conditions for SaIE have been intensely studied before; however, to date no study has focused on predisposing host genetic factors to SaIE. The present study aimed to identify genetic polymorphisms associated with SaIE by a Genome-Wide Association Study (GWAS) of 67 patients with definite native valve SaIE (cases) and 72 matched native valve patients with SAB but without IE (controls)...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29669961/aciduricity-and-acid-tolerance-mechanisms-of-streptococcus-anginosus
#15
Minoru Sasaki, Yoshitoyo Kodama, Yu Shimoyama, Taichi Ishikawa, Shigenobu Kimura
Although Streptococcus anginosus constitutes a proportion of the normal flora of the gastrointestinal and genital tracts, and the oral cavity, it has been reported that S. anginosus infection could be closely associated with abscesses at various body sites, infective endocarditis, and upper gastrointestinal cancers. The colonization in an acidic environment due to the aciduricity of S. anginosus could be the etiology of the systemic infection of the bacteria. To elucidate the aciduricity and acid tolerance mechanisms of the microbe, we examined the viability and growth of S...
April 17, 2018: Journal of General and Applied Microbiology
https://www.readbyqxmd.com/read/29669686/cow-neck-veins-and-endocarditis-a-mooo%C3%A2-ving-mystery
#16
EDITORIAL
Ronald K Woods
No abstract text is available yet for this article.
March 31, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29667140/multidisciplinary-management-of-pyogenic-spondylodiscitis-epidemiological-and-clinical-features-prognostic-factors-and-long-term-outcomes-in-207-patients
#17
Enrico Pola, F Taccari, G Autore, F Giovannenze, V Pambianco, R Cauda, G Maccauro, M Fantoni
PURPOSE: Pyogenic spondylodiscitis (PS) is a potentially life-threatening infection burdened by high morbidity rates. Despite the rising incidence, the proper management of PS is still controversial. Aim of this study was to describe the clinical features of PS and to evaluate the prognostic factors and the long-term outcomes of a large population of patients. METHODS: 207 cases of PS treated from 2008 to 2016 with a 2-year follow-up were enrolled. Clinical data from each patient were recorded...
April 17, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29666712/eustachian-valve-endocarditis-echocardiographic-diagnosis-in-a-critical-care-patient
#18
Mariana Alves, Rita Faria, António Messias, Carlos Meneses-Oliveira
Eustachian valve endocarditis is rare. A literature review revealed that only 29 cases have been reported and, among them, there is only one mention of an intensive care unit (ICU) admission. We present an 82-year-old man without previous medical records who presented with septic shock with multiple organ dysfunction. The patient was admitted to the ICU and deteriorated with combined shock (septic + cardiogenic). A second ultrasound screen detected a prominent Eustachian valve with mobile multilobulated vegetation attached...
2018: Case Reports in Critical Care
https://www.readbyqxmd.com/read/29666615/significance-of-streptococcus-gallolyticus-subsp-gallolyticus-association-with-colorectal-cancer
#19
REVIEW
Ewa Pasquereau-Kotula, Mariana Martins, Laetitia Aymeric, Shaynoor Dramsi
Streptococcus gallolyticus subsp. gallolyticus Sgg (formerly known as S. bovis type I) is the main causative agent of septicemia and infective endocarditis (IE) in elderly and immunocompromised persons. It belongs to the few opportunistic bacteria, which have been strongly associated to colorectal cancer (CRC). A literature survey covering a period of 40 years (1970-2010) revealed that 65% of patients diagnosed with an invasive Sgg infection had a concomitant colorectal neoplasia. Sgg is associated mainly with early adenomas and may thus constitute an early marker for CRC screening...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29666027/puerperium-related-stroke-due-to-nonbacterial-thrombotic-endocarditis
#20
Manuel Chacón-Díaz, Roberto Ruiz-Cordero, Helard Miranda-Aguilar, Josias Rios-Ortega, Fernando Córdova-Gómez, Julio Morón-Castro
No abstract text is available yet for this article.
April 14, 2018: Revista Española de Cardiología
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