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https://www.readbyqxmd.com/read/28229822/myocardial-performance-index-in-active-and-inactive-paediatric-systemic-lupus-erythematosus
#1
Anant Khositseth, Wasana Prangwatanagul, Kanchana Tangnararatchakit, Soamarat Vilaiyuk, Nantawan Su-Angka
OBJECTIVES: To evaluate cardiac structure and function in paediatric SLE patients without clinical evidence of cardiovascular disease in active and inactive diseases. METHODS: Patients aged ≤20 years who fulfilled the diagnostic criteria of active SLE underwent transthoracic echocardiography to evaluate cardiac structure and function, and were then followed up echocardiographically every 3-4 months until SLE disease was inactive. Patients with heart failure, myocarditis, pericarditis, endocarditis, coronary artery disease, or abnormal structural heart disease were excluded...
February 3, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28224037/tooth-extraction-in-a-patient-after-autologous-skeletal-myoblast-sheet-transplantation-for-severe-dilated-cardiomyopathy
#2
Kohei Okuyama, Yuki Sakamoto, Tomofumi Naruse, Souichi Yanamoto, Masahiro Umeda
The authors describe the first case of tooth extraction in a patient treated with autologous skeletal myocardial sheet transplantation for severe dilated cardiomyopathy. This condition is associated with significant morbidity and mortality that may have identifiable causes or may be idiopathic or inherited. In addition to local disinfection, antimicrobial prophylaxis and continuous anticoagulant therapy during the perioperative period of tooth extraction were needed to prevent infective endocarditis and ensure the success of regenerative therapy of the heart...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28223392/streptococcus-mitis-and-s-oralis-lack-a-requirement-for-cdsa-the-enzyme-required-for-synthesis-of-major-membrane-phospholipids-in-bacteria
#3
Hannah M Adams, Luke R Joyce, Ziqiang Guan, Ronda L Akins, Kelli L Palmer
Synthesis and integrity of the cytoplasmic membrane is fundamental to cellular life. Experimental evolution studies have hinted at unique physiology in the Gram-positive bacteria Streptococcus mitis and S. oralis These organisms commonly cause bacteremia and infectious endocarditis (IE) but are rarely investigated in mechanistic studies of physiology and evolution. Unlike other Gram-positive pathogens, high-level (MIC ≥ 256 μg/mL) daptomycin resistance rapidly emerges in S. mitis and S. oralis after a single drug exposure...
February 21, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28222125/streptococcus-sanguinis-induces-neutrophil-cell-death-by-production-of-hydrogen-peroxide
#4
Ryuichi Sumioka, Masanobu Nakata, Nobuo Okahashi, Yixuan Li, Satoshi Wada, Masaya Yamaguchi, Tomoko Sumitomo, Mikako Hayashi, Shigetada Kawabata
Streptococcus is the dominant bacterial genus in the human oral cavity and a leading cause of infective endocarditis. Streptococcus sanguinis belongs to the mitis group of streptococci and produces hydrogen peroxide (H2O2) by the action of SpxB, a pyruvate oxidase. In this study, we investigated the involvement of SpxB in survival of S. sanguinis in human blood and whether bacterial H2O2 exhibits cytotoxicity against human neutrophils. Results of a bactericidal test with human whole blood revealed that the spxB mutation in S...
2017: PloS One
https://www.readbyqxmd.com/read/28221109/potentially-zoonotic-bartonella-in-bats-from-france-and-spain
#5
Matthew J Stuckey, Henri-Jean Boulouis, Florence Cliquet, Evelyne Picard-Meyer, Alexandre Servat, Nidia Aréchiga-Ceballos, Juan E Echevarría, Bruno B Chomel
We detected Bartonella in 11 of 109 insectivorous bats from France and 1 of 26 bats from Spain. These genetic variants are closely related to bat-associated Bartonella described in Finland and the United Kingdom and to B. mayotimonensis, the agent of a human endocarditis case in the United States.
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28217736/gestational-choriocarcinoma-complicated-by-infective-endocarditis-during-chemotherapy
#6
Tadaharu Nakasone, Yutaka Nagai, Yoshihisa Arakaki, Yoshino Kinjyo, Yoichi Aoki
•Little is known about the history of cancer patients complicated with IE.•It is very important to do the chemotherapy without delay for choriocarcinoma.•We report a case of choriocarcinoma complicated by IE during EMA-CO.•An accurate diagnosis/prompt treatment decisions are important for cancer with IE.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28217558/the-scid-mouse-model-for-identifying-virulence-determinants-in-coxiella-burnetii
#7
Erin J van Schaik, Elizabeth D Case, Eric Martinez, Matteo Bonazzi, James E Samuel
Coxiella burnetii is an intracellular, zoonotic pathogen that is the causative agent of Q fever. Infection most frequently occurs after inhalation of contaminated aerosols, which can lead to acute, self-limiting febrile illness or more serve chronic infections such as hepatitis or endocarditis. Macrophages are the principal target cells during infection where C. burnetii resides and replicates within a unique phagolysosome-like compartment, the Coxiella-containing vacuole (CCV). The first virulence determinant described as necessary for infection was full-length lipopolysaccarride (LPS); spontaneous rough mutants (phase II) arise after passage in immuno-incompetent hosts...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28214763/emergency-valve-surgery-for-infective-endocarditis-complicated-by-acute-intracranial-hemorrhage-a-case-report
#8
Takasumi Goto, Toshihiro Ohata, Takayuki Shijo, Daisuke Yoshioka, Mitsunori Kaneko
INTRODUCTION: Optimal timing of surgical treatment for infective endocarditis (IE) complicated by intracranial hemorrhage remains controversial. PRESENTATION OF CASE: A 43-year-old man with IE received appropriate antibiotic therapy but had recurrence of cerebral infarction and intracranial hemorrhage (ICH). Emergency valve surgery was performed 2days after ICH onset because of heart failure and recurrence of cerebral complications. Postoperatively, he showed no neurologic symptoms; neuroimaging showed no enlargement of ICH...
February 11, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28213933/evaluation-of-vegetation-size-and-its-relationship-with-septic-pulmonary-embolism-in-tricuspid-valve-infective-endocarditis-a-real-time-3dtee-study
#9
Hiroto Utsunomiya, Javier Berdejo, Sayuki Kobayashi, Hirotsugu Mihara, Yuji Itabashi, Takahiro Shiota
BACKGROUND: Tricuspid valve infective endocarditis (TVIE) causes septic pulmonary embolism (PE). However, the impact of vegetation size on PE is not fully elucidated. METHODS: In 26 consecutive patients with definite TVIE according to Duke criteria, we tested clinical, microbiological, and echocardiographic data including real time three-dimensional transesophageal echocardiography (3DTEE) as potential predictors of PE. 3DTEE measurement of maximum length of vegetation (MLV) was obtained with Advanced QLAB Quantification Software by cropping the 3D volume with the appropriate 2D plane to obtain the largest value...
February 18, 2017: Echocardiography
https://www.readbyqxmd.com/read/28213924/diagnostic-paradox-ruptured-aneurysm-of-sinus-of-valsalva-simulating-tricuspid-valve-endocarditis
#10
Mehar Hoda, Arushi Verma, Sridevi Alapati, Srilatha Alapati, Tharakanatha R Yarrabolu
Rupture of aneurysm of sinus of Valsalva into the right atrium mimicking tricuspid valve endocarditis is a rare presentation. We review a case of spontaneous rupture of aneurysm of sinus of Valsalva into the right atrium presenting as a murmur. Transthoracic echocardiogram showed a mobile mass that appeared to be attached to the tricuspid valve leaflet with moderate tricuspid regurgitation suggestive of tricuspid valve endocarditis. The diagnosis was confirmed as spontaneous rupture of noncoronary sinus in to the right atrium by transesophageal echocardiogram...
February 18, 2017: Echocardiography
https://www.readbyqxmd.com/read/28213367/antibiotic-prophylaxis-for-infective-endocarditis-a-systematic-review-and-meta-analysis
#11
Thomas J Cahill, James L Harrison, Paul Jewell, Igho Onakpoya, John B Chambers, Mark Dayer, Peter Lockhart, Nia Roberts, David Shanson, Martin Thornhill, Carl J Heneghan, Bernard D Prendergast
OBJECTIVE: The use of antibiotic prophylaxis (AP) for prevention of infective endocarditis (IE) is controversial. In recent years, guidelines to cardiologists and dentists have advised restriction of AP to high-risk groups (in Europe and the USA) or against its use at all (in the UK). The objective of this systematic review was to appraise the evidence for use of AP for prevention of bacteraemia or IE in patients undergoing dental procedures. METHODS: We conducted electronic searches in Medline, Embase, Cochrane Library and ISI Web of Science...
February 17, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28209306/successful-coil-embolization-of-a-ruptured-mycotic-aneurysm-that-developed-three-days-after-septic-embolic-infarction-case-report-and-review-of-the-literature
#12
Joshua L Wang, Archana P Hinduja, Ciarán J Powers
BACKGROUND: Infectious intracranial aneurysms (IIAs) are rare entities and are often associated with septic embolus from infectious endocarditis. They may develop rapidly and carry a higher risk of rupture and mortality compared to noninfectious aneurysms. However, the development and rupture of an IIA within 48h in a patient with septic infarction patient is exceedingly rare. CASE DESCRIPTION: In this report, we describe a 25-year-old male who presented with left-sided hemiparesis and dysarthria from septic embolus to the right middle cerebral artery...
February 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28209176/infective-endocarditis-causing-mitral-valve-stenosis-a-rare-but-deadly-complication-a-case-report
#13
Michael A Hart, Gautam R Shroff
BACKGROUND: Infective endocarditis rarely causes mitral valve stenosis. When present, it has the potential to cause severe hemodynamic decompensation and death. There are only 15 reported cases in the literature of mitral prosthetic valve bacterial endocarditis causing stenosis by obstruction. This case is even more unusual due to the mechanism by which functional mitral stenosis occurred. CASE PRESENTATION: We report a case of a 23-year-old white woman with a history of intravenous drug abuse who presented with acute heart failure...
February 17, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28208915/an-unusual-occurrence-of-methicillin-resistant-staphylococcal-endocarditis-with-vancomycin-creep-phenomenon-a-therapeutic-challenge
#14
S Sneha, Shanthan Venishetty, Shubha Seshadri, M Sudhakar Rao, Chiranjay Mukhopadhyay
Infective endocarditis by Methicillin Resistant Staphylococcus aureus (MRSA) bacteraemia is a common association and carries a high mortality. However, rising Minimum Inhibitory Concentrations (MICs) for vancomycin amongst MRSA strains is an emerging threat which carries poor prognosis and higher mortality. Here, we report a case of 41-year-old young non-addict gentleman presenting with fever of 3 days duration following recovery from an acute kidney injury necessitating haemodialysis. Systemic examination revealed signs of mitral regurgitation and left sided cerebellar signs...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28206705/erysipelothrix-rhusiopathiae-bloodstream-infection-a-22-year-experience-at-mayo-clinic-minnesota
#15
E M Tan, J R Marcelin, N Adeel, R J Lewis, M J Enzler, P K Tosh
Erysipelothrix rhusiopathiae is a facultatively anaerobic Gram-positive bacillus found mostly in swine, fish and sheep. E. rhusiopathiae classically causes cutaneous eruptions in butchers, fish handlers and veterinarians. Based solely on case reports, 90% of E. rhusiopathiae bloodstream infections (BSI) have been associated with infective endocarditis (IE). To assess the true frequency of IE in E. rhusiopathiae BSI as well as other clinical associations, we performed a retrospective cohort analysis of E...
February 16, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28205197/recurrent-endocarditis-causing-severe-obstruction-of-bioprosthetic-tricuspid-valve
#16
Karolina Kupczyńska, Piotr Lipiec, Błażej W Michalski, Jarosław D Kasprzak
No abstract text is available yet for this article.
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28204495/early-in-vitro-development-of-daptomycin-non-susceptibility-in-high-level-aminoglycoside-resistant-enterococcus-faecalis-predicts-the-efficacy-of-the-combination-of-high-dose-daptomycin-plus-ampicillin-in-an-in-vivo-model-of-experimental-endocarditis
#17
J M Pericàs, C García-de-la-Mària, M Brunet, Y Armero, J García-González, G Casals, M Almela, E Quintana, C Falces, S Ninot, D Fuster, J Llopis, F Marco, A Moreno, J M Miró
No abstract text is available yet for this article.
February 14, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28203580/unusual-presentation-of-diffuse-large-b-cell-lymphoma-with-splenic-infarcts
#18
Vivek Kumar, Parita Soni, Vishangi Dave, Jonathan Harris
A 67-year-old man presented with a 3-day history of abdominal pain, fever, and significant weight loss over 2 months. Physical examination revealed left upper quadrant tenderness, hepatomegaly, splenomegaly, and bilateral pitting edema but peripheral lymphadenopathy was absent. Laboratory tests showed anemia, thrombocytopenia, elevated prothrombin time (PT), partial thromboplastin time (PTT), and increased lactate dehydrogenase (LDH). PTT was corrected completely in mixing study. Further workup for the cause of coagulopathy revealed decreased levels of all clotting factors except factor VIII and increase fibrinogen levels, which ruled out disseminated intravascular coagulation (DIC)...
January 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28203574/resolution-of-q-fever-associated-cryoglobulinemia-with-anti-cd20-monoclonal-antibody-treatment
#19
Kellie L Hawkins, Edward N Janoff, Robert W Janson
Immunologic phenomena can complicate chronic infections with Coxiella burnetii (Q fever), including immune complex deposition causing vasculitis, neuropathy, and glomerulonephritis. We describe the case of a man with Q fever endocarditis, mixed cryoglobulinemia, and life-threatening vasculitis driven by immune complex deposition who was successfully treated with B cell depleting therapy (rituximab).
January 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28203536/clinical-outcomes-of-robotic-mitral-valve-repair-a-single-center-experience-in-korea
#20
Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Jae Won Lee
BACKGROUND: Since the inception of robotic mitral valve repair (MV) in 2007 at our institution, it has become an acceptable surgical option with proven efficacy and safety. The objective of this study is to analyze the early and long-term clinical outcomes of patients undergoing robotic MV repair. METHODS: A total of 310 patients (aged 48.4±13.7 years, 201 males) undergoing robotic MV repair using the da Vinci system (Intuitive Surgical, Inc., Sunnyvale, CA) between August 2007 and December 2015 in our institution were evaluated...
January 2017: Annals of Cardiothoracic Surgery
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