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https://www.readbyqxmd.com/read/28626824/atypical-chronic-central-serous-chorioretinopathy-with-cystoid-macular-edema-therapeutic-response-to-medical-and-laser-therapy
#1
Jiun L Do, Lisa C Olmos de Koo, Hossein Ameri
PURPOSE: To describe an atypical case of chronic central serous chorioretinopathy (CSCR). METHODS: A 58-year-old man with longstanding, bilateral visual impairment was self-referred for a second opinion. RESULTS: Findings by direct ophthalmoscopy, optical coherence tomography, fluorescein angiography, and fundus autofluorescence (FAF) were suggestive of atypical, chronic CSCR. Treatment with oral anti-mineralocorticoids resulted in moderate improvement, and photodynamic therapy (PDT) had minimal effect...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28600300/retinal-vessels-functionality-in-eyes-with-central-serous-chorioretinopathy
#2
Livia Tomasso, Lucia Benatti, Alessandro Rabiolo, Adriano Carnevali, Ilaria Zucchiatti, Lea Querques, Francesco Bandello, Giuseppe Querques
PURPOSE: To analyse static characteristics and dynamic functionality of retinal vessels in eyes with central serous chorioretinopathy (CSCR) by means of Dynamic Vessel Analyzer (DVA). METHODS: Patients presenting with treatment-naïve CSCR and normal subjects (controls) matched for age and sex between May 2015 and November 2015 were enrolled in the study. Participants underwent a complete ophthalmological examination, including dynamic and static retinal vessels analysis by DVA...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28524143/-features-of-psycho-emotional-state-of-patients-with-central-serous-chorioretinopathy
#3
A A Shchuko, T N Yureva, A N Zlobina
AIM: to investigate peculiarities of psycho-emotional reactions in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: The study involved 35 patients with CSCR (mean age of 47.7±8.5 years) and 26 volunteers without visual impairment (mean age of 35.8±4.5 years). Their psycho-emotional state was studied using the SCL-90-R questionnaire (the severity of psychopathological symptomatology), TOBOL method (the type of attitude to the disease), Ways of Coping Questionnaire (WCQ) (strategies for controlling behavior), Spielberger-Hanin method (the level of anxiety), and the VFQ-25 questionnaire (quality of life)...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28524134/-oct-morphometric-and-angiographic-parallels-between-different-variants-of-central-serous-chorioretinopathy
#4
I E Panova, T B Shaimov, V A Shaimova
Central serous chorioretinopathy (CSCR) is a frequent cause of vision deterioration. Often it is associated with type 1 neovascularization under the pigment retinal epithelium (RPE). Optical coherence tomography angiography (OCT-angiography) enables non-invasive and contrast-free detection of neovessels in any retinal layer, which makes the method appropriate for diagnostics in CSCR. AIM: to investigate OCT-morphometric and angiographic parallels between different CSCR courses. MATERIAL AND METHODS: The study included 37 patients with CSCR...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28500259/central-serous-chorioretinopathy-secondary-to-tuberculosis-cause-or-coincidence
#5
Perwez Khan, Lubna Khan, Nikhat Anjum, Nutan Saxena
32-year-old male with diagnosis of central serous chorioretinopathy (CSCR) in both eyes and negative history of administration of any medicine was treated with bilateral focal laser at leakage point, with visual recovery. Recurrence occurred after 2 years in right eye and was treated successfully with acetazolamide. Second recurrence occurred after 1 year. Acetazolamide was restarted, but no improvement was noted. Thorough re-evaluation of the patient revealed a family history of tuberculosis. Ancillary investigations rendered the presumptive diagnosis of tuberculosis, and antituberculosis treatment led to visual recovery with no recurrences...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28497336/the-overlapping-spectrum-of-flat-irregular-pigment-epithelial-detachment-investigated-by-optical-coherence-tomography-angiography
#6
Francesco Pichi, Mariachiara Morara, Chiara Veronese, Antonio P Ciardella
PURPOSE: To describe the OCT angiography characteristics of flat irregular pigment epithelial detachments (PEDs), an overlapping tomographic feature of various macular disorders. METHODS: Consecutive patients with a dimpled retinal pigment epithelium profile on OCT, referred for a second opinion, were enrolled. Fluorescein (FA) and indocyanine green angiography (ICGA) were performed in all patients and compared to previous examinations, when available. In all patients, enhanced depth imaging-OCT and OCT angiography were performed upon referral and at subsequent follow-ups...
May 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28424788/fully-automated-robust-system-to-detect-retinal-edema-central-serous-chorioretinopathy-and-age-related-macular-degeneration-from-optical-coherence-tomography-images
#7
Samina Khalid, M Usman Akram, Taimur Hassan, Ammara Nasim, Amina Jameel
Maculopathy is the excessive damage to macula that leads to blindness. It mostly occurs due to retinal edema (RE), central serous chorioretinopathy (CSCR), or age related macular degeneration (ARMD). Optical coherence tomography (OCT) imaging is the latest eye testing technique that can detect these syndromes in early stages. Many researchers have used OCT images to detect retinal abnormalities. However, to the best of our knowledge, no research that presents a fully automated system to detect all of these macular syndromes is reported...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28380092/frequency-of-fibromyalgia-syndrome-in-patients-with-central-serous-chorioretinopathy
#8
Ayse Balkarli, Muhammet Kazim Erol, Ozgur Yucel, Yusuf Akar
Purpose: To ınvestigate frequency of fibromyalgia syndrome (FMS) among patients with central serous chorioretinopathy (CSCR). Methods: The study included 83 patients with CSCR and 201 age- and sex-matched healthy controls; the mean age was 47.5 ± 11.3 years in the CSCR group (18 women; 21.7%) and 47.2 ± 11.2 years in the control group (44 women; 21.9%). All participants were assessed for FMS based on 2010 American College of Rheumatology diagnostic criteria and for depression and anxiety with the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI)...
January 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28367162/factors-affecting-the-visual-outcome-in-acute-central-serous-chorioretinopathy
#9
Qamar Ul Islam, Muhammad Asad Farooq, Mohammad Asim Mehboob
OBJECTIVE: To determine the visual outcome in patients with acute Central serous chorioretinopathy (CSCR) and to analyze the association of clinical, angiographic and tomographic factors with final visual outcome in Pakistani population. METHODS: This study was conducted at AFIO Rawalpindi and PNS Shifa Naval hospital Karachi from November 2011 to August 2016. Fifty five eyes of 53 patients with acute CSCR were included. All patients underwent a detailed ophthalmic examination including SD OCT imaging at baseline, One month and three month and FFA was performed at baseline...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28328282/frequency-of-erectile-dysfunction-in-males-with-central-serous-chorioretinopathy
#10
Ayse Balkarli, Muhammet Kazim Erol, Soner Yalcinkaya, Rumeysa Selvinaz Erol
OBJECTIVES: To evaluate the frequency of sexual dysfunction and associated factors in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: Fifty-eight CSCR patients who met the inclusion criteria and 99 age- and sex-matched healthy controls were prospectively investigated for sexual dysfunction and associated factors. All participants were investigated using the Beck Depression Inventory (BDI), Beck Anxiety Scale (BAS), and the15-question Index of Erectile Function-15 (IIEF-15) and by extensive examination of CSCR, associated factors, and confounding factors...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28108906/a-novel-marker-in-acute-central-serous-chorioretinopathy-thiol-disulfide-homeostasis
#11
Hasan Altinkaynak, Piraye Zeynep Kurkcuoglu, Mehtap Caglayan, Mücella Arıkan Yorgun, Nilay Yuksel, Pınar Kosekahya, Cemile Koca, Yasin Toklu
PURPOSE: The aim of this study was to compare dynamic thiol/disulfide homeostatic status in acute central serous chorioretinopathy (CSCR) patients by using a novel and automated assay determining dynamic thiol/disulfide homeostasis. METHODS: Fifty-one patients with acute CSCR (study group) and 65 healthy individuals (control group) were enrolled in this study. Diagnosis of acute CSCR was made clinically and using spectral-domain RTVue OCT (optical coherence tomography) (Optovue, Fremont, CA)...
January 21, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28067724/acute-central-serous-chorioretinopathy-factors-influencing-episode-duration
#12
Alejandra Daruich, Alexandre Matet, Laetitia Marchionno, Jean-Dominique De Azevedo, Aude Ambresin, Irmela Mantel, Francine Behar-Cohen
PURPOSE: To evaluate the influence of clinical and multimodal imaging parameters on the duration of acute central serous chorioretinopathy (CSCR) episodes. METHODS: Consecutive patients with first, treatment-naïve central serous chorioretinopathy episodes presenting within 20 days of symptoms onset were prospectively included. They were reevaluated 15 days to 20 days later, followed by monthly evaluation for 6 months. Subfoveal choroidal thickness (SFCT), fluorescein leakage intensity on fluorescein angiography, elevation of retinal pigment epithelium (RPE) lesions at leakage sites, focal/multifocal pattern of indocyanine green angiography (ICGA) at baseline, time-dependent pattern of subretinal fluid (SRF) resorption on OCT using volume segmentation, history of corticosteroid intake and mean blood pressure were evaluated using univariate (Log rank test) and multivariate (Cox proportional hazard regression) survival analysis...
January 6, 2017: Retina
https://www.readbyqxmd.com/read/28000244/sensitivity-and-specificity-of-multispectral-imaging-in-detecting-central-serous-chorioretinopathy
#13
Xuemei Zhu, Yong Cheng, Xue Pan, Enzhong Jin, Shanshan Li, Mingwei Zhao, Xiaoxin Li
BACKGROUND AND OBJECTIVE: Central serous chorioretinopathy (CSCR) is a common and idiopathic retinal disorder that affects young to middle aged adults. The aim of this study was to describe the characteristics of eyes with CSCR using a light-emitting diode (LED)-based multispectral imaging (MSI) system and to evaluate the diagnostic reliability of MSI compared to fluorescein angiography (FA) in detecting CSCR. MATERIALS AND METHODS: A total of 56 eyes among 52 patients with 1 or more retinal pigment epithelium (RPE) abnormality were retrospectively enrolled in the study...
December 21, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27929707/systemic-mineralocorticoid-antagonists-in-the-treatment-of-central-serous-chorioretinopathy
#14
REVIEW
Dong Yang, Dean Eliott
Central serous chorioretinopathy (CSCR) is a challenging disease characterized by subretinal serous fluid accumulation. The complex pathogenesis is still not fully understood, but is thought to be multifactorial and involves exogenous and endogenous factors affecting the choroid and retinal pigment epithelium. The involvement of corticosteroids is undisputed, while the contribution of mineralocorticoid pathways is under investigation. This review addresses the proposed pathogenesis models and the evidence for systemic treatment of CSCR with mineralocorticoid antagonists...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27882013/effect-of-half-adult-dose-of-oral-rifampicin-300mg-in-patients-with-idiopathic-central-serous-chorioretinopathy
#15
Muhammad Saim Khan, Murtaza Sameen, Arshad Ali Lodhi, Munawar Ahmed, Noman Ahmed, Mustafa Kamal, Sameen Afzal Junejo
OBJECTIVES: To evaluate the effect of half adult dose of oral Rifampicin on mean change in best corrected visual acuity and central macular thickness in patients with central serous chorioretinopathy. METHODS: Thirty-eight eyes of 31 patients with idiopathic central serous chorioretinopathy (CSCR) were registered. Unaided Visual acuity, best corrected visual acuity was documented and detailed slit lamp examination along with dilated ophthalmoscopy was performed...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27847640/choroidal-thickness-in-older-patients-with-central-serous-chorioretinopathy
#16
Caio V Regatieri, Eduardo A Novais, Lauren Branchini, Mehreen Adhi, Emily D Cole, Ricardo Louzada, Mark Lane, Elias Reichel, Jay S Duker
BACKGROUND: To investigate the choroidal thickness in older patients with central serous chorioretinopathy (CSCR) compared to age-matched normal subjects. METHODS: Fifteen patients (30 eyes) with CSCR, all aged ≥60 years, and 21 age-matched normal subjects (21 eyes) underwent high-definition raster scanning using SD-OCT. Both eyes from CSCR patients were included in the analysis. The eyes in patients with CSCR were divided into two groups: active CSCR (17 eyes) if there was foveal-involving subretinal fluid and inactive contralateral eye group (13 eyes)...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27803862/clinical-research-of-fenofibrate-and-spironolactone-for-acute-central-serous-chorioretinopathy
#17
Yong Chai, Rong-Qiang Liu, Jing-Lin Yi, Ling-Hong Ye, Jing Zou, Nan Jiang, Yi Shao
AIM: To compare the effectiveness of combined fenofibrate and spironolactone with fenofibrate alone for treatment of central serous chorioretinopathy (CSCR). METHODS: Totally 60 patients (60 eyes) with a history of acute CSCR were randomed into two groups: group A with combination of fenofibrate (200 mg) and spironolactone (100 mg), and group B with only fenofibrate (200 mg). They were taken half an hour before meals and once per day for 8wk. The changes of the visual acuity, subjective symptom, ocular surface disease index (OSDI), the tear film and optical coherence tomography were observed at 2, 4, 6, and 8wk before and after treatment...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27757733/comparison-of-two-mineralcorticosteroids-receptor-antagonists-for-the-treatment-of-central-serous-chorioretinopathy
#18
Francesco Pichi, Paola Carrai, Antonio Ciardella, Francine Behar-Cohen, Paolo Nucci
PURPOSE: To evaluate the effect of oral spironolactone and eplerenone, two specific antagonists of the mineralocorticoid receptor, in central serous chorioretinopathy (CSCR). METHODS: In this prospective, placebo-controlled trial, sixty patients with persistent CSCR were assigned to three treatment group. Twenty patients in Group 1 were treated with 25 mg of spironolactone (Aldactone; Pfizer) for 1 week, then increased to 50 mg for the following 3 weeks, then shifted to eplerenone 50 mg for 1 month...
October 18, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27617266/scleral-resection-in-chronic-central-serous-chorioretinopathy-complicated-by-exudative-retinal-detachment
#19
Pradeep Venkatesh, Rohan Chawla, Koushik Tripathy, Harsh Inder Singh, Ravi Bypareddy
BACKGROUND: Effective therapeutic options are limited for the management of chronic central serous chorioretinopathy (CSCR) complicated by exudative retinal detachments (RD). The authors describe the resolution of one such case following partial thickness scleral resection with mitomycin C. CASE PRESENTATION: This 39-year-old male presented with a unilateral inferior exudative RD in the right eye. There was no history of steroid use either locally or systemically...
2016: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/27539765/frequency-of-systemic-risk-factors-in-central-serous-chorioretinopathy
#20
Qamar Ul Islam, Muhammad Kashif Hanif, Sheraz Tareen
OBJECTIVE: To determine the frequency of various systemic risk factors associated with acute central serous chorioretinopathy (CSCR) in our setup. STUDY DESIGN: Descriptive case series. PLACE AND DURATION OF STUDY: Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, from July 2011 to June 2014. METHODOLOGY: All consecutive patients with acute CSCR who presented in the outpatient department during the study period were recruited...
August 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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