keyword
https://read.qxmd.com/read/38537222/comprehension-and-usefulness-of-spanish-language-health-information-about-depression-treatment
#1
JOURNAL ARTICLE
Beatriz Manzor-Mitrzyk, Ana I Lopez-Medina, Karen B Farris
US Latine adults who prefer the Spanish language for healthcare encounter communication have high risk of health disparitiesm in part from low organizational health literacy, mental health stigma and discrimination. Latine organizational health literacy includes the provision of culturally responsive, language concordant health information, which supports good comprehension and could mitigate some health disparities. We conducted a pilot study to assess commonly provided patient health information handouts about depression treatment and antidepressant consumer medication information sheets...
March 27, 2024: Health Education Research
https://read.qxmd.com/read/38537198/biokc-a-collaborative-platform-for-curation-and-annotation-of-molecular-interactions
#2
JOURNAL ARTICLE
Carlos Vega, Marek Ostaszewski, Valentin Grouès, Reinhard Schneider, Venkata Satagopam
Curation of biomedical knowledge into systems biology diagrammatic or computational models is essential for studying complex biological processes. However, systems-level curation is a laborious manual process, especially when facing ever-increasing growth of domain literature. New findings demonstrating elaborate relationships between multiple molecules, pathways and cells have to be represented in a format suitable for systems biology applications. Importantly, curation should capture the complexity of molecular interactions in such a format together with annotations of the involved elements and support stable identifiers and versioning...
March 27, 2024: Database: the Journal of Biological Databases and Curation
https://read.qxmd.com/read/38537185/influence-of-body-mass-normalization-on-the-correlations-between-muscle-cross-sectional-area-and-physical-performance-outcomes-in-older-women
#3
JOURNAL ARTICLE
Ty B Palmer, Bailey M Palmer
AIMS: Normalization is a method used to account for body mass in clinical practice and research. It is unclear if this method will improve the correlation between muscle cross-sectional area (CSA) and physical performance. We examined the correlations between quadriceps muscle morphology parameters and physical performance outcomes in older women. Material and methods: Twenty older women participated in this study. Ultrasound imaging was used to measure quadriceps muscle CSA and echo intensity...
January 30, 2024: Medical Ultrasonography
https://read.qxmd.com/read/38537183/a-radiomics-model-based-on-transrectal-ultrasound-for-predicting-prostate-cancer
#4
JOURNAL ARTICLE
Yanhua Huang, Hongwei Qian, Yuanyuan Zheng, Huiming Song, Xiatian Liu
AIM: Prostate cancer (PCa) is one of the most common neoplasms in men. However, the value of ultrasound-based radiomics for diagnosing PCa remains uncertain. MATERIAL AND METHODS: We retrospectively analyzed ultrasonic and clinical data from 373 patients. Patients were divided into two groups according to the pathological results. Radiomics features wereextracted from TRUS, and we screened the optimal features to construct radiomics models. Relationships between clinical characteristics and prostate lesions were identified by univariate and multivariate logistic regression analysis...
February 7, 2024: Medical Ultrasonography
https://read.qxmd.com/read/38537178/-what-if-i-got-rejected-by-the-girl-i-would-rather-stop-the-pills-barriers-and-facilitators-of-adherence-to-antiretroviral-therapy-for-emerging-adults-aged-18-29-living-with-hiv-in-zimbabwe
#5
JOURNAL ARTICLE
Rebecca Jopling, Wilson Mutsvuke, Madison Fertig, Conall O'Cleirigh, Walter Mangezi, Melanie Abas
Emerging adults aged 18-29 have high rates of viral non-suppression, and poorer adherence to ART when compared to older adults. Semi-structured interviews were conducted with 24 emerging adults in Zimbabwe who had a recent history of viral non-suppression, to explore barriers and facilitators of adherence to ART. Interviews were coded using inductive thematic analysis. The mean age of participants was 23, 65% were male, and 79% reported acquiring HIV at birth. Twelve barriers to adherence were identified. Hiding HIV status due to the possible negative consequences of disclosure had a significant impact on adherence to ART...
March 27, 2024: AIDS Care
https://read.qxmd.com/read/38537171/society-s-role-in-addressing-mental-health-grief-crisis-a-call-for-public-support
#6
EDITORIAL
Vickie M Mays, Susan D Cochran
No abstract text is available yet for this article.
March 2024: American Journal of Public Health
https://read.qxmd.com/read/38537155/giredestrant-for-estrogen-receptor-positive-her2-negative-previously-treated-advanced-breast-cancer-results-from-the-randomized-phase-ii-acelera-breast-cancer-study
#7
JOURNAL ARTICLE
Miguel Martín, Elgene Lim, Mariana Chavez-MacGregor, Aditya Bardia, Jiong Wu, Qingyuan Zhang, Zbigniew Nowecki, Felipe Melo Cruz, Rustem Safin, Sung-Bae Kim, Christian Schem, Alberto J Montero, Sarah Khan, Reeti Bandyopadhyay, Heather M Moore, Mahesh Shivhare, Monika Patre, Jorge Martinalbo, Laura Roncoroni, Pablo Diego Pérez-Moreno, Joohyuk Sohn
PURPOSE: To compare giredestrant and physician's choice of endocrine monotherapy (PCET) for estrogen receptor-positive, HER2-negative, advanced breast cancer (BC) in the phase II acelERA BC study (ClinicalTrials.gov identifier: NCT04576455). METHODS: Post-/pre-/perimenopausal women, or men, age 18 years or older with measurable disease/evaluable bone lesions, whose disease progressed after 1-2 lines of systemic therapy (≤1 targeted, ≤1 chemotherapy regimen, prior fulvestrant allowed) were randomly assigned 1:1 to giredestrant (30 mg oral once daily) or fulvestrant/aromatase inhibitor per local guidelines (+luteinizing hormone-releasing hormone agonist in pre-/perimenopausal women, and men) until disease progression/unacceptable toxicity...
March 27, 2024: Journal of Clinical Oncology
https://read.qxmd.com/read/38537152/ligand-field-sensitive-spin-acceleration-in-the-iron-catalyzed-2-2-cycloaddition-of-unactivated-alkenes-and-dienes
#8
JOURNAL ARTICLE
Hanna H Cramer, Coralie Duchemin, Carli B Kovel, Junho Kim, Matthew V Pecoraro, Paul J Chirik
Redox-active pyridine(diimine) (PDI) iron catalysts promote the reversible [2 + 2] cycloaddition of alkenes and dienes to cyclobutane derivatives that have applications ranging from fuels to chemically recyclable polymers. Metallacycles were identified as key intermediates, and spin crossover from the singlet to the triplet surface was calculated to facilitate the reductive coupling step responsible for the formation of the four-membered ring. In this work, a series of sterically and electronically differentiated PDI ligands was studied for the [2 + 2] cycloaddition of ethylene and butadiene to vinylcyclobutane...
March 27, 2024: Journal of the American Chemical Society
https://read.qxmd.com/read/38537142/first-report-of-fusarium-falciforme-causing-root-and-rhizome-rot-of-epimedium-sagittatum-in-china
#9
JOURNAL ARTICLE
Leixia Chu, Diandian Li, Wenchuan Hou, Zhiwei Dan, Xiaojie Wang, Chengming Dong
Epimedium sagittatum (Sieb.et Zucc.) Maxim., a perennial herb, is an important medicinal plant, rich in flavonoids, and widely used in the treatment of sexual dysfunction, rheumatic disease, and cancers (Tan et al. 2016). In July 2022, a disease of root and rhizome was found on E. sagittatum aged 1-8 years in a planting area (266 ha) of Zhumadian City (32°58'12" N, 114°37'48" E), Henan Province, China. The disease incidence per field (660 m2 ) was around 10-15% in six randomly surveyed fields planted with about 10,000 E...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537141/first-record-of-diplodia-gallae-causing-branch-cankers-on-declining-scarlet-oak-quercus-coccinea-in-virginia
#10
JOURNAL ARTICLE
Devin Bily, Tashi Gyatso, Matt Wolanski, Amanda Conrad, Connor Goolsby, Lori A Chamberlin, Katlin M DeWitt
Members of Botryosphaeria s.l. have an extensive history as cankering pathogens of stressed and declining oak trees in the eastern United States (Ferreira et al. 2021). The host range, distribution, and virulence among two closely related species, Diplodia corticola and D. gallae, remains unclear (Brazee et al. 2023). On 15 August 2023, a survey was conducted at a declining natural hardwood site in Shenandoah County, Virginia (GPS coordinates 38.922089, -78.606125). One mature Quercus coccinea tree that displayed scorched leaf margins and branch dieback was felled and a cankered branch from the crown was sampled (Fig...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537128/the-impact-of-a-training-intervention-on-knowledge-confidence-and-attitudes-of-professionals-in-a-community-acquired-brain-injury-service-about-assistive-technology-for-cognition-a-before-and-after-survey
#11
JOURNAL ARTICLE
Helen MacDonald, Gemma Bradley, Katie Cummings, Gemma Eskandari, Charlotte Price, Lara Weller
Assistive Technology for Cognition (ATC) can help people to compensate for cognitive impairments following Acquired Brain Injury (ABI). Examples include mainstream devices such as smartphones, watches and environmental controls, and bespoke devices such as medication devices or specific educational software. Evidence suggests that professional support is key to people successfully adopting ATC, yet low confidence amongst clinicians and perceptions about barriers are often cited as reasons for not recommending ATC in practice...
March 27, 2024: Assistive Technology: the Official Journal of RESNA
https://read.qxmd.com/read/38537126/developing-accessible-speech-technology-with-users-with-dysarthric-speech
#12
JOURNAL ARTICLE
Elizabeth Howarth, Geena Vabulas, Sean Connolly, Dawn Green, Sara Smolley
The Voiceitt app is designed for people with dysarthric speech, to support vocal communication and access to voice-driven technologies. Sixty-six participants were recruited to test the Voiceitt app and share feedback with developers. Most had physical, sensory, or cognitive impairments in addition to atypical speech. The project team liaised with individuals, their families and local support teams to provide access to the app and associated equipment. Testing was user-led, with participants asked to identify and test use cases most relevant to their daily lives over three months or more...
March 27, 2024: Assistive Technology: the Official Journal of RESNA
https://read.qxmd.com/read/38537123/excitatory-cerebellar-transcranial-direct-current-stimulation-boosts-the-leverage-of-prior-knowledge-for-predicting-actions
#13
JOURNAL ARTICLE
Viola Oldrati, Niccolò Butti, Elisabetta Ferrari, Zaira Cattaneo, Cosimo Urgesi, Alessandra Finisguerra
The cerebellum causally supports social processing by generating internal models of social events based on statistical learning of behavioral regularities. However, whether the cerebellum is only involved in forming or also in using internal models for the prediction of forthcoming actions is still unclear. We used cerebellar transcranial Direct Current Stimulation (ctDCS) to modulate the performance of healthy adults in using previously learned expectations in an action prediction task. In a first learning phase of this task, participants were exposed to different levels of associations between specific actions and contextual elements, to induce the formation of either strongly or moderately informative expectations...
February 28, 2024: Social Cognitive and Affective Neuroscience
https://read.qxmd.com/read/38537119/constructing-linear-oriented-pre-vascularized-human-spinal-cord-tissues-for-spinal-cord-injury-repair
#14
JOURNAL ARTICLE
Caixia Fan, Hui Cai, Lulu Zhang, Xianming Wu, Junyan Yan, Lifang Jin, Baowei Hu, Jiaxiong He, Yanyan Chen, Yannan Zhao, Jianwu Dai
Repairing spinal cord injury (SCI) is a global medical challenge lacking effective clinical treatment. Developing human-engineered spinal cord tissues that can replenish lost cells and restore a regenerative microenvironment offers promising potential for SCI therapy. However, creating vascularized human spinal cord-like tissues that mimic the diverse cell types and longitudinal parallel structural features of spinal cord tissues remains a significant hurdle. In present study, vascularized spinal cord tissues (VSCT) were engineered using embryonic human spinal cord-derived neural cells and endothelial cells on linear ordered collagen scaffolds (LOCS)...
March 27, 2024: Advanced Healthcare Materials
https://read.qxmd.com/read/38537110/deletion-of-dictyostelium-tpc2-gene-forms-multi-tipped-structures-regulates-autophagy-and-cell-type-patterning
#15
JOURNAL ARTICLE
Madhubala Rathore, Ashima Thakur, Shweta Saran
BACKGROUND INFORMATION: Two pore channels (TPCs) are voltage-gated ion channel superfamily members that release Ca2+ from acidic intracellular stores and are ubiquitously present in both animals and plants. Starvation initiates multicellular development in Dictyostelium discoideum. Increased intracellular calcium levels bias Dictyostelium cells towards the stalk pathway and thus we decided to analyze the role of TPC2 in development, differentiation, and autophagy. RESULTS: We showed TPC2 protein localizes in lysosome-like acidic vesicles and the in situ data showed stalk cell biasness...
March 27, 2024: Biology of the Cell
https://read.qxmd.com/read/38537107/exploring-psychosocial-distress-in-caregivers-of-children-and-youth-with-special-health-care-needs
#16
JOURNAL ARTICLE
Régine Placide Reaves, Giovanna De Oliveira, Angel Johann Solorzano Martinez
PURPOSE: Caring for a child or youth with special health care needs (CYSHCN) can be overwhelming. Parents and caregivers may experience psychosocial distress, such as depression, frustration, and hopelessness. The purpose of the current study was to gain further insight into families' perspectives on the psychosocial impacts of caring for CYSHCN to identify gaps in health care systems and strengthen systems of support. METHOD: A qualitative descriptive design was used in 16 parents and caregivers...
April 1, 2024: Journal of Psychosocial Nursing and Mental Health Services
https://read.qxmd.com/read/38537106/analyzing-the-relationship-between-self-efficacy-in-protecting-against-substance-use-and-loneliness-in-adolescents-a-cross-sectional-survey
#17
JOURNAL ARTICLE
Kübra Kayaoğlu, Duygu Özer
PURPOSE: To analyze the relationship between self-efficacy in protecting against substance use and loneliness in adolescents. METHOD: This descriptive, cross-sectional study comprised 400 adolescents. A Sociodemographic Data Form, Self-Efficacy for Adolescents Protecting Against Substance Abuse Scale (SEAPSAS), and Short-Form UCLA Loneliness Scale (ULS-8) were used for data collection. Regression analysis and Pearson correlation analysis, as well as descriptive statistics, were used in data analysis...
April 1, 2024: Journal of Psychosocial Nursing and Mental Health Services
https://read.qxmd.com/read/38537082/khmer-translation-and-cultural-adaptation-of-the-locomotor-capabilities-index-5
#18
JOURNAL ARTICLE
Nerrolyn Ramstrand, Alan Maddock, Thearith Heang, Nil Ean, Sisary Kheng
BACKGROUND: Mobility is a major goal of prosthetic and orthotic rehabilitation, and use of outcome measures to evaluate mobility is necessary for good clinical practice. To support the use of outcome measures worldwide, work is needed to translate relevant instruments and adapt them for use in multiple cultures. OBJECTIVES: The objective of this research was to use a standardized method to translate the Locomotor Capabilities Index-5 (LCI-5) into Khmer, the national language in Cambodia, and to evaluate its cultural integrity by assessing it with a group of prosthesis and orthosis users...
March 22, 2024: Prosthetics and Orthotics International
https://read.qxmd.com/read/38537074/development-of-the-psu-child-pump
#19
JOURNAL ARTICLE
Christopher Scheib, Raymond Newswanger, Joshua Cysyk, Karl Bohnenberger, Branka Lukic, Lichong Xu, Eric Yeager, Kirby Bletcher, Patrick Leibich, Quandashia Jackson, Heidi Flory, Mindy Tillinger, William Weiss, Gerson Rosenberg, Choon-Sik Jhun
The Pennsylvania State University (PSU) Child Pump, a centrifugal continuous-flow ventricular assist device (cf-VAD), is being developed as a suitable long-term implantable device for pediatric heart failure patients between 10 and 35 kg, body surface area (BSA) of 0.5-1.2 m2, 1-11 years of age, and requiring a mean cardiac output of 1.0-3.5 L/min. In-vitro hydraulic and hemodynamic performances were evaluated on a custom mock circulatory loop with ovine blood. Normalized index of hemolysis (NIH) was evaluated under four conditions: 1) 8,300 rpm, 3...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38537068/fear-of-recurrence-among-lung-cancer-survivors-a-theoretical-model-validation
#20
JOURNAL ARTICLE
Qiuhong Chen, Yunqin Weng, Fangfang Wang, Xiaoyan Yang, Wei-Ti Chen, Feifei Huang
BACKGROUND: Fear of cancer recurrence (FCR) significantly impacts the treatment and prognosis of lung cancer survivors. However, the mechanisms and factors contributing to FCR and its related consequences in lung cancer remain poorly understood. OBJECTIVE: To evaluate the validity of the Lee-Jones Theoretical Model of FCR in lung cancer survivors. METHODS: A cross-sectional survey was conducted among 257 lung cancer survivors who had undergone surgical treatment 1 year prior...
March 27, 2024: Cancer Nursing
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