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Coronary slow flow

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https://www.readbyqxmd.com/read/29629270/left-atrial-function-and-coronary-slow-flow-is-there-diastolic-dysfunction-or-not
#1
Luca Longobardo
No abstract text is available yet for this article.
January 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29512098/effects-of-hyperbaric-oxygen-on-vascular-endothelial-function-in-patients-with-slow-coronary-flow
#2
Yuan Li, Huiping Zhang, Yi Liang, Wei Wang, Tongshun Xu, Jifang Zhang, Wenliang Xiao, Tao Wang
BACKGROUND: To improve therapy for slow coronary flow (SCF), the effects of hyperbaric oxygen (HBO) therapy on vascular endothelial function in SCF patients is the focus of this investigation. METHODS: Ninety-eight patients who exhibited chest discomfort were retrospectively analyzed, and di-agnosed with SCF by coronary artery angiography at the Third Hospital of Hebei Medical University, Shijiazhuang, China from 2014 to 2016. The patients were divided into two groups according to the following treatment: HBO group (n = 48) and the control group (n = 50)...
2018: Cardiology Journal
https://www.readbyqxmd.com/read/29484206/effect-of-coronary-slow-flow-on-intrinsicoid-deflection-of-qrs-complex
#3
Sabri Seyis
Coronary slow flow is a rare, clinically important entity observed in acute coronary syndrome. The pathophysiological mechanism is not fully elucidated. We investigated patients with chest pain who had angiographic features consistent with the coronary slow flow. One hundred ten patients were included. Electrocardiography, echocardiography, and angiography results were retrospectively noted. The mean age was 56.4. Fifty-eight were male, and fifty-two were female. The control group consisted of patients with normal angiography...
2018: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29460660/early-repolarization-pattern-in-the-coronary-slow-flow-phenomenon
#4
Murat Sucu, Berzal Ucaman, Gökhan Altunbas
BACKGROUND: The coronary slow flow phenomenon (CSFP) is well-documented, and the early repolarization pattern (ERP) has recently been shown to be a risk factor for the development of malignant ventricular arrhythmias. METHODS: Those with true CSFP were included as cases and those with normal angiograms were included as controls. We assessed J-point elevation on surface electrocardiograms (ECGs) and defined ERP as notching or slurring of the terminal portion of the QRS takeoff...
February 20, 2018: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/29459578/trapping-balloon-technique-for-removal-of-the-burr-in-rotational-atherectomy
#5
Kei Yamamoto, Kenichi Sakakura, Yousuke Taniguchi, Yoshimasa Tsurumaki, Hiroshi Wada, Shin-Ichi Momomura, Hideo Fujita
Because rotational atherectomy (RA) has several unique complications, such as burr entrapment, vessel perforation, and slow flow, it is important for interventional cardiologists to be familiar with bailout procedures for such complications. The principal part of bailout procedures is to keep a guidewire in the target coronary artery during the procedure. However, it is not easy to keep a guidewire in the same position during the removal of a burr because the length of the RA guidewires is 300 cm, and the removal of a burr requires collaboration between the primary operator and an assistant...
February 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29399097/atorvastatin-improves-coronary-flow-and-endothelial-function-in-patients-with-coronary-slow-flow
#6
Hongmei Niu, Zhenzhen Wei, Yanling Zhang, Jian He, Danyan Jia
The underlying mechanisms behind the effect of atorvastatin on patients with coronary slow flow (CSF) remain largely unknown. To investigate the possible underlying molecular mechanisms 108 patients were divided into atorvastatin group and control group. Coronary flow was quantified according to corrected TIMI frame count (CTFC). Serum high sensitivity C-reactive protein (hs-CRP), lipids, ET-1, interleukin (IL)-6, NO, circulating endothelial progenitor cell (cEPC) count, adhesion, migration and proliferation were measured in pretreatment and post-treatment...
January 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29381922/immediate-versus-deferred-stenting-for-patients-undergoing-primary-or-emergent-percutaneous-coronary-intervention-protocol-for-a-systematic-review-and-meta-analysis
#7
REVIEW
Yong Liu, Sheikh Mohammed Shariful Islam, Clara K Chow, Shiqun Chen, Muhammad Umer Siddiqui, Qiang Li, Kai-Yang Lin, Kun Wang, Guoli Sun, Ying-Ling Zhou, Jiyan Chen, David Brieger
INTRODUCTION: Primary or emergent percutaneous coronary intervention (PCI) with stenting is the standard treatment for patients with ST-segment elevation myocardial infarction (STEMI) or non-STEMI acute coronary syndromes (ACS) at high risk. The value of delayed stenting following balloon-facilitated reperfusion in these patients is largely unknown. METHODS AND ANALYSIS: This systematic review aims to assess whether delayed stenting (vs immediate stenting) improves angiographic and cardiovascular clinical outcomes for patients with STEMI or non-STEMI ACS undergoing primary or emergent PCI...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29339698/association-of-interleukin-1-gene-cluster-polymorphisms-with-coronary-slow-flow-phenomenon
#8
Ferit Onur Mutluer, Dilek Ural, Barış Güngör, Osman Bolca, Tolga Aksu
OBJECTIVE: Coronary slow flow phenomenon (CSFP) is characterized by the decreased rate of contrast progression in epicardial coronary arteries in the absence of significant coronary stenosis. Mounting evidence has showed a significant association between inflammation and CSFP severity. This study aimed to evaluate possible associations between interleukin-1 receptor antagonist (IL-1ra) gene variable number tandem repeat (VNTR), IL-1ß -511 single nucleotide (SNP), and IL-1ß+3954 SNP mutations with CSFP...
January 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29314204/telmisartan-ameliorates-vascular-endothelial-dysfunction-in-coronary-slow-flow-phenomenon-csfp
#9
Zhe Jin, Qindong Tan, Bei Sun
Coronary slow flow phenomenon (CSFP) is a coronary microvascular disorder with an increasing morbidity, and currently, available therapies are of limited clinical value for its cure. Hence, it is urgent to find a novel approach to CSFP treatment. Several studies show that endothelial dysfunction plays a critical role in the aetiology of CSFP. Telmisartan (TMST) is a clinically available anti-hypertensive medicine and has shown its potential properties for improving vascular endothelial function. Thus, we aimed to investigate the effect of TMST on endothelial dysfunction in CSFP, Endothelial-dependent flow-mediated vasodilation, serum levels of nitric oxide, adiponectin, and endothelin-1 were surveyed before and after 3 months of TMST treatment...
January 2018: Cell Biochemistry and Function
https://www.readbyqxmd.com/read/29223872/relationship-between-thrombus-age-in-aspirated-coronary-material-and-mid-term-major-adverse-cardiac-and-cerebrovascular-events-in-patients-with-acute-myocardial-infarction
#10
Kensaku Nishihira, Yoshisato Shibata, Atsushi Yamashita, Nehiro Kuriyama, Yujiro Asada
BACKGROUND AND AIMS: Recent studies have shown that coronary thrombus histopathology is associated with impaired myocardial reperfusion and poor clinical outcome in patients with acute myocardial infarction (AMI). We sought to investigate the age of thrombi aspirated during percutaneous coronary intervention (PCI) in patients with AMI and evaluate the relationship between histopathologic findings and major adverse cardiac and cerebrovascular events (MACCEs) defined as all-cause death, stroke, or myocardial infarction within 6 months of PCI...
January 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29216999/characteristics-predictors-and-mechanisms-of-thrombosis-in-coronary-bioresorbable-scaffolds-differences-between-early-and-late-events
#11
Tommaso Gori, Melissa Weissner, Svenja Gönner, Franziska Wendling, Helen Ullrich, Stephen Ellis, Remzi Anadol, Alberto Polimeni, Thomas Münzel
OBJECTIVES: The study sought to investigate the incidence, characteristics, predictors, and possible mechanisms of early and 3-year coronary scaffold thrombosis (ScT). BACKGROUND: An increased incidence of both early and late ScT has been shown in randomized trials. METHODS: Consecutive patients were enrolled in a single-center registry. Quantitative coronary angiography was performed. Incidence and predictors of ScT were assessed with Kaplan-Meier and Cox regression analyses...
December 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29201440/evaluation-of-ghrelin-levels-and-endothelial-functions-in-patients-with-coronary-slow-flow-phenomenon
#12
Oğuzhan Çelik, Erkan Demirci, Mustafa Aydın, Turgut Karabag, Macit Kalçık
Background: Ghrelin has recently been reported to have beneficial effects on cardiac contractile functions and coronary blood flow. The main purpose of this study was to investigate the role of ghrelin in the pathogenesis of coronary slow flow (CSF) together with endothelial functions. Methods: Twenty-five patients having normal coronary arteries with CSF and 25 controls with normal coronary flow were included into the study. The quantitative measurement of coronary blood flow was performed for each coronary artery using the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method...
September 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/29201435/endothelial-nitric-oxide-synthase-gene-polymorphisms-in-patients-with-slow-coronary-flow
#13
Nurzen Sezgin, Abdullah Tekin, Fatma Belgin Atac, Hasibe Verdi, Alpay Turan Sezgin
Background and aims: The aim of this study was to explore potential associations of the intron 4 variable number of tandem repeats (VNTR) and E298A polymorphisms of the endothelial nitric oxide synthase (eNOS) gene with slow coronary flow (SCF). The association between plasma nitrate and nitrite (NO x ) concentrations and eNOS gene polymorphisms was also assessed. Materials and methods: The intron 4 VNTR and E298A polymorphisms of the eNOS gene were evaluated in the isolated DNA blood samples obtained from the SCF patient group ( n  = 30) and healthy group consisted of age- and sex-matched controls ( n  = 61)...
September 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/29147131/transcriptional-activity-of-tumor-necrosis-factor-alpha-gene-in-peripheral-blood-mononuclear-cells-in-patients-with-coronary-slow-flow
#14
Yousef Rasmi, Morteza Bagheri, Sanaz Faramarz-Gaznagh, Mohadeseh Nemati, Mohammad Hasan Khadem-Ansari, Ehsan Saboory, Mir Hossein Seyed-Mohamadzad, Alireza Shirpoor
BACKGROUND: Coronary slow flow (CSF), an angiographic phenomenon that is characterized by a delayed coronary blood flow in the absence of obstructive coronary artery stenosis, is known as a disorder of the coronary microcirculation. Inflammation has an important role in the vascular hemostasis and endothelial dysfunction especially regarding monocyte adhesion and infiltration. Pro-inflammatory cytokines released by inflammatory cells result in endothelial cell dysfunction and cardiovascular diseases...
July 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29142809/is-left-atrial-function-affected-by-coronary-slow-flow-a-two-dimensional-speckle-tracking-echocardiographic-study
#15
Flora Fallah, Sima Narimani, Shima Yarmohammadi, Ali Hosseinsabet, Arash Jalali
Background: The coronary slow flow phenomenon (CSFP) is the slow passage of the angiographic contrast agent to the distal portion of the coronary artery in the absence of significant stenosis. We evaluated the left atrial (LA) function in patients with the CSFP using two-dimensional speckle-tracking echocardiography (2DSTE). Methods: The LA function was compared through 2DSTE between 36 patients with the CSFP and 36 participants with a normal coronary flow. The two groups were matched for age, sex, hypertension, diabetes mellitus, and the left ventricular function...
October 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29131290/nesfatin-1-levels-in-patients-with-slow-coronary-flow
#16
Mevlüt Serdar Kuyumcu, Aliye Kuyumcu, Çağrı Yayla, Mustafa Bilal Özbay, Mehmet Alagöz, Sefa Ünal, Burak Açar, Özcan Özeke, Gülhan Samur
BACKGROUND: Nesfatin-1 is a novel found anorectic neuropeptide with potent metabolic regulatory effects. AIM: We aimed to evaluate the relationship between Nesfatin-1 levels and slow coronary flow (SCF). METHODS: A total of 60 consecutive patients with SCF and 60 consecutive patients with the normal coronary flow (NCF) were enrolled into the study. Nesfatin-1 level was measured from blood serum samples using enzyme-linked immunosorbent assay test...
November 13, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/29106833/-coronary-ectasias-and-thrombosis
#17
M A Bouzid, H Benamer, X Halna du Fretay
Ectasias and coronary aneurysms are uncommon coronary artery diseases, can coexist and are poorly known. Their principal etiology in adults is coronary atherosclerosis. It has been suggested that these abnormalities would have poor prognosis and that slow flow could lead to in situ thrombosis and distal embolisation. However, ectasias and aneurysms are most often associated with coronary stenosis. We report a series of 47 cases of ectasias and coronary aneurysms with evaluation of the clinical and angiographic characteristics, the therapeutic choices and we review the literature concerning these lesions...
December 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29105688/-valve-in-valve-treatment-of-a-degenerated-supra-annular-stentless-bioprosthesis-using-a-balloon-expandable-transcatheter-valve-in-a-patient-at-high-risk-for-coronary-occlusion
#18
Silvia Mauri, Marco Ferlini, Marco Luigi Aiello, Luca Franco Lanzarini, Eliana Raviola, Fabrizio Gazzoli, Marco Maurelli, Maurizio Ferrario
Transcatheter valve-in-valve treatment of degenerated supra-annular stentless bioprostheses may be challenging and associated with a high risk of coronary occlusion. Preprocedural imaging evaluation is a key step to assess feasibility and to minimize or prevent coronary occlusion. We report the case of a degenerated Freedom Solo valve, treated with a balloon-expandable valve and a previously deflated stent positioned at the level of both coronary ostia. The procedure was successful but stent inflation at the right coronary ostium was required due to slow flow that occurred after valve implantation...
October 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28945162/orbital-atherectomy-for-the-treatment-of-severely-calcified-coronary-lesions-evidence-technique-and-best-practices
#19
Evan Shlofmitz, Brad J Martinsen, Michael Lee, Sunil V Rao, Philippe Généreux, Joe Higgins, Jeffrey W Chambers, Ajay J Kirtane, Emmanouil S Brilakis, David E Kandzari, Samin K Sharma, Richard Shlofmitz
The presence of severe coronary artery calcification is associated with higher rates of angiographic complications during percutaneous coronary intervention (PCI), as well as higher major adverse cardiac events compared with non-calcified lesions. Incorporating orbital atherectomy (OAS) for effective preparation of severely calcified lesions can help maximize the benefits of PCI by attaining maximal luminal gain (or stent expansion) and improve long-term outcomes (by reducing need for revascularization). Areas covered: In this manuscript, the prevalence, risk factors, and impact of coronary artery calcification on PCI are reviewed...
October 4, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28887713/determinants-of-slow-flow-following-stent-implantation-in-intravascular-ultrasound-guided-primary-percutaneous-coronary-intervention
#20
Yusuke Watanabe, Kenichi Sakakura, Yousuke Taniguchi, Kei Yamamoto, Hiroshi Wada, Hideo Fujita, Shin-Ichi Momomura
Slow flow is a serious complication in primary percutaneous coronary intervention (PCI) and is associated with poor clinical outcomes. Intravascular ultrasound (IVUS)-guided PCI may improve clinical outcomes after drug-eluting stent implantation. The purpose of this study was to seek the factors of slow flow following stent implantation, including factors related to IVUS-guided primary PCI. The study population consisted of 339 ST-elevation myocardial infarction patients, who underwent stent deployment with IVUS...
September 8, 2017: Heart and Vessels
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