keyword
https://read.qxmd.com/read/38545894/developing-a-diabetes-discharge-order-set-for-patients-with-diabetes-on-insulin
#1
JOURNAL ARTICLE
Elizabeth Miles, Melissa McKnight, Claire C Schmitz, Chelsea R McElroy, Jana L Wardian, Valerie Shostrom, Preethi Polavarapu
BACKGROUND: Insulin, a high-risk medication, is prone to prescribing errors. Patients with diabetes experience higher hospitalization rates and extended hospital stays. Prescription errors, such as missing orders, inappropriate insulin type, missing instructions, and lack of appropriate intensification of insulin regimens are common issues. This project explored the use of system-based interventions and educational tools to minimize errors and improve the quality of insulin discharge regimens...
March 28, 2024: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/38541864/drug-related-problems-among-older-inpatients-at-a-tertiary-care-setting
#2
JOURNAL ARTICLE
Porrawee Pramotesiri, Krongtong Putthipokin, Sirasa Ruangritchankul
Background: Older persons are more likely to have multiple chronic diseases, leading to the simultaneous use of many medications. This situation results in increased drug-related problems (DRPs), which are the causes of adverse health outcomes. Therefore, we aimed to evaluate the prevalence of and associated risk factors for exposure to >1 criterion of DRPs among older adults admitted to a tertiary care hospital. Methods: We conducted a cross-sectional study involving 357 participants aged ≥60 years admitted to Ramathibodi Hospital from 1 February 2022 to 30 November 2022...
March 13, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38538448/pharmaceutical-recommendations-for-therapeutic-appropriateness-in-multiple-sclerosis-patients
#3
JOURNAL ARTICLE
María Del Mar Sánchez Suárez, Alicia Martín Roldán, Maria Rosa Cantudo Cuenca, Alberto Jiménez Morales
OBJECTIVE: To determine the prevalence of PIMDINAC criteria and to implement pharmacological interventions in a population with multiple sclerosis over 55 years of age. METHODS: Retrospective observational open-label study including patients with multiple sclerosis aged 55 years and older between December 2022 and February 2023. The main variable determined was the percentage of compliance with the PIMDINAC criteria. RESULTS: Ninety-five patients were included, with the presence of PIMDINAC criteria detected in 67...
March 26, 2024: Farmacia Hospitalaria
https://read.qxmd.com/read/38535886/stop-in-time-how-to-reduce-unnecessary-antibiotics-in-newborns-with-late-onset-sepsis-in-neonatal-intensive-care
#4
REVIEW
Domenico Umberto De Rose, Maria Paola Ronchetti, Alessandra Santisi, Paola Bernaschi, Ludovica Martini, Ottavia Porzio, Andrea Dotta, Cinzia Auriti
The fear of missing sepsis episodes in neonates frequently leads to indiscriminate use of antibiotics, and prescription program optimization is suggested for reducing this inappropriate usage. While different authors have studied how to reduce antibiotic overprescription in the case of early onset sepsis episodes, with different approaches being available, less is known about late-onset sepsis episodes. Biomarkers (such as C-reactive protein, procalcitonin, interleukin-6 and 8, and presepsin) can play a crucial role in the prompt diagnosis of late-onset sepsis, but their role in antimicrobial stewardship should be further studied, given that different factors can influence their levels and newborns can be subjected to prolonged therapy if their levels are expected to return to zero...
March 19, 2024: Tropical Medicine and Infectious Disease
https://read.qxmd.com/read/38534718/one-hundred-explicit-definitions-of-potentially-inappropriate-prescriptions-of-antibiotics-in-hospitalized-older-patients-the-results-of-an-expert-consensus-study
#5
JOURNAL ARTICLE
Nicolas Baclet, Emmanuel Forestier, Gaëtan Gavazzi, Claire Roubaud-Baudron, Vincent Hiernard, Rozenn Hequette-Ruz, Serge Alfandari, Hugues Aumaître, Elisabeth Botelho-Nevers, Pauline Caraux-Paz, Alexandre Charmillon, Sylvain Diamantis, Thibaut Fraisse, Pierre Gazeau, Maxime Hentzien, Jean-Philippe Lanoix, Marc Paccalin, Alain Putot, Yvon Ruch, Eric Senneville, Jean-Baptiste Beuscart
BACKGROUND: In geriatrics, explicit criteria for potentially inappropriate prescriptions (PIPs) are useful for optimizing drug use. OBJECTIVE: To produce an expert consensus on explicit definitions of antibiotic-PIPs for hospitalized older patients. METHODS: We conducted a Delphi survey involving French experts on antibiotic stewardship in hospital settings. During the survey's rounds, the experts gave their opinion on each explicit definition, and could suggest new definitions...
March 20, 2024: Antibiotics
https://read.qxmd.com/read/38533252/the-prescription-trends-and-dosing-appropriateness-analysis-of-novel-oral-anticoagulants-in-ischemic-stroke-patients-a-retrospective-study-of-9-cities-in-china
#6
JOURNAL ARTICLE
Mingfen Wu, Hailun Jiang, Kefu Yu, Zhigang Zhao, Bin Zhu
Background: Novel oral anticoagulants (NOACs) have been recommended by guidelines as the first-line drugs for preventing cardiogenic stroke. We aimed to provide an overview of the prescription trends and dosing appropriateness of NOACs in China. Methods: We conducted a retrospective analysis of NOAC prescriptions using the Hospital Prescription Analysis Cooperation Project data from 2016 to 2022. Various patient features, such as gender, age, city, year, source, department visited, original diagnosis, dosing, cost, and insurance type, were collected and analyzed to examine the trends and dosing appropriateness of NOAC usage in ischemic stroke patients...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38530599/how-well-do-ed-physician-practices-align-with-the-caep-acute-atrial-fibrillation-checklist-for-stroke-prevention-and-disposition
#7
JOURNAL ARTICLE
Samara Adler, Amanda M S Mattice, Debra Eagles, Krishan Yadav, Sean Hui, Althaf Azward, Nikesh Pandey, Ian Stiell
OBJECTIVES: Acute atrial fibrillation (AF)/flutter (AFL) is a common emergency department (ED) presentation. In 2021, an updated version of CAEP's Acute AF/AFL Best Practices Checklist was published, seeking to guide management. We assessed the alignment with and safety of application of the Checklist, regarding stroke prevention and disposition. METHODS: This health records review included adults presenting to two tertiary care academic EDs between January and August 2022 with a diagnosis of acute AF/AFL...
March 26, 2024: CJEM
https://read.qxmd.com/read/38529187/pharmacological-treatments-and-medication-related-problems-in-nursing-homes-in-catalonia-a-multidisciplinary-approach
#8
JOURNAL ARTICLE
Emilie Anderssen-Nordahl, Margarita Sánchez-Arcilla Rosanas, Montserrat Bosch Ferrer, Mònica Sabaté Gallego, Eladio Fernández-Liz, Antonio San-José, Maria Estrella Barceló-Colomer
Background: Aging correlates with increased frailty, multi-morbidity, and chronic diseases. Furthermore, treating the aged often entails polypharmacy to achieve optimal disease management, augmenting medication-related problems (MRPs). Few guidelines and tools address the problem of polypharmacy and MRPs, mainly within the institutionalized elderly population. Routine pharmacological review is needed among institutionalized patients. This pharmacological review may improve with a multidisciplinary approach of a collaboration of multiple health professionals...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38525745/deprescribing-in-older-poly-treated-patients-affected-with-dementia
#9
JOURNAL ARTICLE
Pietro Gareri, Luca Gallelli, Ilaria Gareri, Vincenzo Rania, Caterina Palleria, Giovambattista De Sarro
Polypharmacy is an important issue in older patients affected by dementia because they are very vulnerable to the side effects of drugs'. Between October 2021 and September 2022, we randomly assessed 205 old-aged outpatients. The study was carried out in a Center for Dementia in collaboration with a university center. The primary outcomes were: (1) deprescribing inappropriate drugs through the Beers and STOPP&START criteria; (2) assessing duplicate drugs and the risk of iatrogenic damage due to drug-drug and drug-disease interactions...
February 26, 2024: Geriatrics
https://read.qxmd.com/read/38525265/community-pharmacist-intervention-in-doxycycline-self-medication-for-acne-among-pregnant-women-in-saudi-arabia
#10
JOURNAL ARTICLE
Marwan Alrasheed, Wael Hamdy Mansy, Mohamed Naser Al-Arifi
INTRODUCTION: Self-medication during pregnancy remains a prevalent global phenomenon, with pregnant women often relying on their own judgment to manage symptoms. Objective: This study aimed to assess community pharmacist practice regarding self-medication requests for acne treatment in pregnant women within Saudi Arabia. METHODS: A descriptive, observational cross-sectional study was conducted in Riyadh, Saudi Arabia. Community pharmacists completed a questionnaire after interacting with a simulated customer (SC) seeking doxycycline for a pregnant woman...
May 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/38521288/role-of-clinical-pharmacy-anticoagulation-service-on-apixaban-prescribing-appropriateness-in-atrial-fibrillation-in-saudi-arabia
#11
REVIEW
Elkholy Emad, Elshammaa Khaled, Bajnaid Eshtiaq, Aboelenin Fatima, Shalaby Ghada
BACKGROUND: Inappropriate DAOC dosing is precuarious and frequently encountered . Apixaban is the most reported DOAC to be inappropriately dosed. We examined the effect of adding a Clinical Pharmacist to the cardiology team rounds to the standard practice in Apixaban prescription patterns in a tertiary center in KSA. OBJECTIVE: To determine the effect of clinical pharmacy services on Apixaban dose appropriateness upon discharge in Atrial Fibrillation patient pobulation ...
March 22, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38520324/evaluation-of-a-clinical-decision-support-system-and-an-automated-electronic-health-record-alert-on-outpatient-prescribing-of-cefdinir
#12
JOURNAL ARTICLE
Ashleah Courtney, Gregory Cook, Margarita Silio
Acute bacterial upper respiratory infections are common indications for antibiotics in pediatrics, and many prescriptions may be inappropriate. Novel approaches to outpatient antimicrobial stewardship interventions are needed. This quasi-experimental study of an order set and best practice advisory alert targeting cefdinir prescriptions demonstrated an 8.4% decrease in cefdinir prescribing (p=<0.001).
March 23, 2024: Journal of the Pediatric Infectious Diseases Society
https://read.qxmd.com/read/38513206/improving-community-antibiotic-prescribing-to-keep-antibiotics-working-in-aotearoa-new-zealand
#13
JOURNAL ARTICLE
Mark G Thomas
Antibiotic resistance, principally a consequence of the human use of antibiotics dispensed in the community, is a relentlessly growing threat to human health in Aotearoa New Zealand. Reducing the prescription of antibiotics for conditions in which they confer no benefit is the most effective method of slowing the spread of antibiotic resistance. In Aotearoa New Zealand, as in many other nations, antibiotic "treatment" of acute respiratory tract infections is the most important component of unnecessary antibiotic use...
March 22, 2024: New Zealand Medical Journal
https://read.qxmd.com/read/38506864/-microbiota-in-food-allergy-prebiotics-probiotics-and-synbiotics
#14
JOURNAL ARTICLE
Pablo Moreno
The close relationship between the microbiota and allergic diseases has been known for several years, particularly food allergy. Although the best studied microbiota is that related to bacteria, viruses, parasites and fungi are also constituents of this, although their role is not definitively clarified. The microbial world interacts with the human body constantly, we are in daily contact with an infinite and innumerable number of varieties of microbes in our environment, some of them can pass through the body without causing any harm, while others generate undesirable risk for the body...
December 31, 2023: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://read.qxmd.com/read/38500716/assessing-the-rationale-of-prescribing-carbapenems-among-hospitalized-patients-with-documented-penicillin-allergy-implications-for-stewardship
#15
JOURNAL ARTICLE
Anne-Valérie Burgener-Gasser, Jeanne Fasel, Delia Halbeisen, Karin Hartmann, Maja Weisser-Rohacek, Carole Kaufmann, Sarah Tschudin-Sutter
BACKGROUND: A reported history of penicillin allergy frequently leads to the prescription of carbapenems as a substitute for penicillin to avoid allergic reactions. Such self-reported allergies need to be accurately characterized to identify targeted antibiotic stewardship interventions that potentially minimize unnecessary carbapenem use. DESIGN: Retrospective cohort study. METHOD: The proportion of hospitalized patients with penicillin allergy history receiving carbapenem prescriptions was evaluated between January 1st, 2017 and December 31st, 2018 at the University Hospital Basel, Switzerland...
2024: Antimicrob Steward Healthc Epidemiol
https://read.qxmd.com/read/38500005/communicating-diagnostic-uncertainty-reduces-expectations-of-receiving-antibiotics-two-online-experiments-with-hypothetical-patients
#16
JOURNAL ARTICLE
Elisabeth D C Sievert, Lars Korn, Marina Gross, Ana Paula Santana, Robert Böhm, Cornelia Betsch
The overprescription of antibiotics due to diagnostic uncertainty and inappropriate patient expectations influence antimicrobial resistance. This research assesses (i) whether communicating diagnostic uncertainty reduces expectations of receiving antibiotics and (ii) which communication strategies minimise unintended consequences of such communication. In two experimental online studies conducted in January and April 2023, participants read a vignette describing a doctor consultation for an ear infection and expressed their expectations of receiving antibiotics, trust in their doctor, rated the doctor's reputation and provided their intention to get a second doctor's opinion...
March 18, 2024: Applied Psychology. Health and Well-being
https://read.qxmd.com/read/38499365/sleep-disturbance-in-people-living-with-dementia-or-mild-cognitive-impairment-a-realist-review-of-general-practice
#17
JOURNAL ARTICLE
Aidin Aryankhesal, Jessica Blake, Geoff Wong, Molly Megson, Simon Briscoe, Louise Allan, Niall M Broomfield, Zenahrai Eastwood, Leanne Greene, Andrea Hilton, Anne Killett, Alpar S Lazar, Rachael Litherland, Gill Livingston, Ian Maidment, Joanne Reeve, George Rook, Sion Scott, Jinpil Um, Jayden van Horik, Chris Fox
BACKGROUND: Sleep disturbance is a prevalent condition among people living with dementia (PLwD) or mild cognitive impairment (MCI). Its assessment and management within primary care is complex because of the comorbidities, older age, and cognitive impairment typical of this patient group. AIM: To explore how primary care clinicians assess, understand, and manage sleep disturbance for PLwD or MCI; if and why such initiatives work; and how people and their carers experience sleep disturbance and its treatment...
March 18, 2024: British Journal of General Practice
https://read.qxmd.com/read/38498514/evaluating-population-level-interventions-to-reduce-inappropriate-antibiotic-use-in-healthcare-and-community-settings-a-systematic-review-protocol
#18
JOURNAL ARTICLE
Shishi Wu, Olivia Magwood, Quanfang Dong, Xiaolin Wei
BACKGROUND: Inappropriate antibiotic use contributes significantly to the global challenge of antimicrobial resistance. While government-initiated population-level interventions are fundamental in addressing this issue, their full potential remains to be explored. This systematic review aims to assess the effectiveness of such interventions in reducing inappropriate antibiotic use among antibiotic providers and users in healthcare and community settings. METHODS: We will conduct a systematic literature search across multiple databases and grey literature sources...
2024: PloS One
https://read.qxmd.com/read/38497086/use-of-potentially-inappropriate-medication-for-elderly-patients-in-tertiary-care-hospital-of-riyadh-saudi-arabia
#19
JOURNAL ARTICLE
Saleh A Alanazi, Abdulrahman Al Amri, Mansour Almuqbil, Abdullah Alroumi, Merna Gamal Mohamed Alahmadi, Joud Obaid Ayesh Alotaibi, May Mohammed Sulaiman Alenazi, Wejdan Hassan Mossad Alahmadi, Alzahraa Hassan Saleh Al Bannay, Shorooq Khaled Ahmad Marai, Safier M AlKhatham, Sarah Al-Kanhal, Syed Mohammed Basheeruddin Asdaq
BACKGROUND AND OBJECTIVES: The elderly population is affected by chronic diseases and lifelong medication. The American Geriatrics Society (AGS) Beers Criteria is a comprehensive approach to medication usage in the older population to reduce potentially inappropriate medication (PIM) use. The purpose of this study was to assess the usage of PIMs in elderly patients upon discharge from tertiary care hospital settings in Riyadh, Saudi Arabia, using the AGS Beers Criteria 2019. METHODS: The data was obtained from the medical records of 1237 patients (>65 years) who were discharged from medical or surgical wards at two hospitals affiliated with King Abdulaziz Medical City...
April 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/38483427/geriatric-emergency-medication-safety-recommendations-gems-rx-modified-delphi-development-of-a-high-risk-prescription-list-for-older-emergency-department-patients
#20
JOURNAL ARTICLE
Rachel M Skains, Jennifer L Koehl, Amer Aldeen, Christopher R Carpenter, Cameron J Gettel, Elizabeth M Goldberg, Ula Hwang, Keith E Kocher, Lauren T Southerland, Pawan Goyal, Carl T Berdahl, Arjun K Venkatesh, Michelle P Lin
STUDY OBJECTIVE: Half of emergency department (ED) patients aged 65 years and older are discharged with new prescriptions. Potentially inappropriate prescriptions contribute to adverse drug events. Our objective was to develop an evidence- and consensus-based list of high-risk prescriptions to avoid among older ED patients. METHODS: We performed a modified, 3-round Delphi process that included 10 ED physician experts in geriatrics or quality measurement and 1 pharmacist...
March 12, 2024: Annals of Emergency Medicine
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