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https://www.readbyqxmd.com/read/28645964/the-predictive-value-of-serial-changes-in-diaphragm-function-during-the-spontaneous-breathing-trial-for-weaning-outcome-a-study-protocol
#1
Pengmin Zhou, Zhongheng Zhang, Yucai Hong, Huabo Cai, Hui Zhao, Peifeng Xu, Yiming Zhao, Shengping Lin, Xuchang Qin, JiaWei Guo, Yun Pan, Junru Dai
INTRODUCTION: There is a variety of tools being used in clinical practice for the prediction of weaning success from mechanical ventilation. However, their diagnostic performances are less than satisfactory. The purpose of this study is to investigate the value of serial changes in diaphragm function measured by ultrasound during the spontaneous breathing trial (SBT) as a weaning predictor. METHODS AND ANALYSIS: This is a prospective observational study conducted in a 10-bed medical emergency intensive care unit (EICU) in a university-affiliated hospital...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28644962/validity-and-reproducibility-of-the-modified-start-back-tool-dutch-version-for-patients-with-neck-pain-in-primary-care
#2
Jasper D Bier, Raymond W J G Ostelo, Bart W Koes, Arianne P Verhagen
OBJECTIVE: To evaluate the reliability and validity of the Dutch version of the STarT Back screening Tool (SBT), for patients with neck pain. METHODS: We modified the SBT to fit patients with neck pain. General practitioners and physiotherapists included patients who completed both a baseline and a follow-up questionnaire at 3 days and 3 months, respectively. The construct validity was assessed using Pearson's correlation between the SBT and the reference questionnaires...
June 15, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28642919/correlation-between-antioxidant-activity-and-bonding-strength-on-bleached-enamel
#3
Hellen Caroliny De Carvalho, Ricardo Danil Guiraldo, Regina Célia Poli-Frederico, Sandra Mara Maciel, Sandra Kiss Moura, Murilo Baena Lopes, Sandrine Bittencourt Berger
Objective: This study used the 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) method to evaluate the percentage of antioxidant activity (%AA) of green tea (GT) and sodium ascorbate (SA) gel in three concentrations (10%, 20% and 30%), and the influence of these concentrations on the microshear bond strength (μ-SBT) values of bleached enamel, using 10% carbamide peroxide (CP). Materials and methods: Eighty intact third molars were selected to perform the μ-SBT test, and were randomly divided into eight experimental groups: G1: positive control - no treatment; G2: negative control - bleached with CP; G3: PC +10% GT; G4: PC +20% GT; G5: PC +30% GT; G6: PC +10% SA; G7: PC +20% SA and G8: PC +30% SA...
December 2016: Acta Biomaterialia Odontologica Scandinavica
https://www.readbyqxmd.com/read/28640202/evaluation-of-legionella-air-contamination-in-healthcare-facilities-by-different-sampling-methods-an-italian-multicenter-study
#4
Maria Teresa Montagna, Osvalda De Giglio, Maria Luisa Cristina, Christian Napoli, Claudia Pacifico, Antonella Agodi, Tatjana Baldovin, Beatrice Casini, Maria Anna Coniglio, Marcello Mario D'Errico, Santi Antonino Delia, Maria Grazia Deriu, Marco Guida, Pasqualina Laganà, Giorgio Liguori, Matteo Moro, Ida Mura, Francesca Pennino, Gaetano Privitera, Vincenzo Romano Spica, Silvia Sembeni, Anna Maria Spagnolo, Stefano Tardivo, Ida Torre, Federica Valeriani, Roberto Albertini, Cesira Pasquarella
Healthcare facilities (HF) represent an at-risk environment for legionellosis transmission occurring after inhalation of contaminated aerosols. In general, the control of water is preferred to that of air because, to date, there are no standardized sampling protocols. Legionella air contamination was investigated in the bathrooms of 11 HF by active sampling (Surface Air System and Coriolis(®)μ) and passive sampling using settling plates. During the 8-hour sampling, hot tap water was sampled three times. All air samples were evaluated using culture-based methods, whereas liquid samples collected using the Coriolis(®)μ were also analyzed by real-time PCR...
June 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28629606/evidence-for-a-higher-resolution-of-hla-genotyping-by-a-new-ngs-based-approach
#5
M Alizadeh, A Walencik, C Frassati, P Moskovtchenko, X Lafarge, F Verite, G Semana
With more than 16,000 alleles identified, the human leucocyte antigen (HLA) system is one of the most polymorphic regions of the human genome. Regarding the crucial role of HLA compatibility in transplantation and especially in Hematopoietic Stem Cell Transplantation, identification of HLA polymorphisms at a high-resolution level is of major interest. Recently, NGS technology has been proposed which appears to be simpler and more informative than the classical molecular methods such as SSP, SSOr and SBT. In the present report, a new set of NGS reagents and the appropriate associated software for sequence analysis are described...
June 16, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28623885/monitoring-the-electric-activity-of-the-diaphragm-during-noninvasive-positive-pressure-ventilation-a-case-report
#6
Fabia Diniz-Silva, Anna Miethke-Morais, Adriano M Alencar, Henrique T Moriya, Pedro Caruso, Eduardo L V Costa, Juliana C Ferreira
BACKGROUND: In patients with post-extubation respiratory distress, delayed reintubation may worsen clinical outcomes. Objective measures of extubation failure at the bedside are lacking, therefore clinical parameters are currently used to guide the need of reintubation. Electrical activity of the diaphragm (EAdi) provides clinicians with valuable, objective information about respiratory drive and could be used to monitor respiratory effort. CASE PRESENTATION: We describe the case of a patient with Chronic Obstructive Pulmonary Disease (COPD), from whom we recorded EAdi during four different ventilatory conditions: 1) invasive mechanical ventilation, 2) spontaneous breathing trial (SBT), 3) unassisted spontaneous breathing, and 4) Noninvasive Positive Pressure Ventilation (NPPV)...
June 17, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28598701/a-double-blind-randomized-pilot-trial-comparing-computerized-cognitive-exercises-to-tetris-in-adolescents-with-attention-deficit-hyperactivity-disorder
#7
Aida Bikic, Torben Østergaard Christensen, James F Leckman, Niels Bilenberg, Søren Dalsgaard
BACKGROUND: The purpose of this trial was to examine the feasibility and efficacy of computerized cognitive exercises from Scientific Brain Training (SBT), compared to the computer game Tetris as an active placebo, in a pilot study of adolescents with attention-deficit/hyperactivity disorder (ADHD). METHOD: Eighteen adolescents with ADHD were randomized to treatment or control intervention for 7 weeks. Outcome measures were cognitive test, symptom, and motivation questionnaires...
June 9, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28589693/antipsychotic-prescription-and-mortality-in-hospitalized-older-persons
#8
Deborah Chiesa, Alessandra Marengoni, Alessandro Nobili, Mauro Tettamanti, Luca Pasina, Carlotta Franchi, Codjo D Djade, Salvatore Corrao, Francesco Salerno, Maura Marcucci, Giuseppe Romanelli, Pier Mannuccio Mannucci
BACKGROUND: Recent scientific reports have shown that older persons treated with antipsychotics for dementia-related behavioural symptoms have increased mortality. However, the impact of these drugs prescribed during hospitalization has rarely been assessed. We aimed to investigate whether antipsychotics are associated with an increased risk of mortality during hospitalization and at 3-month follow-up in elderly inpatients. METHODS: We analyzed data gathered during two waves (2010 and 2012) by the REPOSI (Registro Politerapie Società Italiana Medicina Interna)...
June 6, 2017: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/28588895/evaluation-of-cough-peak-expiratory-flow-as-a-predictor-of-successful-mechanical-ventilation-discontinuation-a-narrative-review-of-the-literature
#9
REVIEW
Chuan Jiang, Antonio Esquinas, Bushra Mina
A crucial step in the transition from mechanical ventilation to extubation is the successful performance of a spontaneous breathing trial (SBT). The American College of Chest Physicians (ACCP) Guidelines recommend removal of the endotracheal tube upon successful completion of a SBT. However, this does not guarantee successful extubation as there remains a risk of re-intubation. Guidelines have outlined ventilator liberation protocols, selected use of non-invasive ventilation on extubation, early mobilization, and dynamic ventilator metrics to prevent and better predict extubation failure...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/28586526/weaning-attempts-cough-strength-and-albumin-are-independent-risk-factors-of-reintubation-in-medical-patients
#10
Meiling Xiao, Jun Duan
BACKGROUND: Reintubation is associated with increased hospital mortality. It is necessary to identify risk factors associated with reintubation. METHODS: A prospective observational study was performed in a respiratory intensive care unit. Medical patients who successfully completed a spontaneous breathing trial (SBT) were enrolled. Before extubation, age, gender, vital signs, acute physiology and chronic health evaluation II (APACHE II) score, SBT attempts, cough peak flow, arterial blood gas tests, and albumin were recorded...
June 6, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28576127/trials-directly-comparing-alternative-spontaneous-breathing-trial-techniques-a-systematic-review-and-meta-analysis
#11
Karen E A Burns, Ibrahim Soliman, Neill K J Adhikari, Amer Zwein, Jessica T Y Wong, Carolina Gomez-Builes, Jose Augusto Pellegrini, Lu Chen, Nuttapol Rittayamai, Michael Sklar, Laurent J Brochard, Jan O Friedrich
BACKGROUND: The effect of alternative spontaneous breathing trial (SBT) techniques on extubation success and other clinically important outcomes is uncertain. METHODS: We searched MEDLINE, EMBASE, CENTRAL, CINAHL, Evidence-Based Medicine Reviews, Ovid Health Star, proceedings of five conferences (1990-2016), and reference lists for randomized trials comparing SBT techniques in intubated adults or children. Primary outcomes were initial SBT success, extubation success, or reintubation...
June 1, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28569152/reliability-and-screening-ability-of-the-start-back-screening-tool-in-patients-with-low-back-pain-in-physiotherapy-practice-a-cohort-study
#12
Hilde Stendal Robinson, Hanne Dagfinrud
BACKGROUND: Low back pain (LBP) is the most common reported musculoskeletal disorder, with large prevalence numbers and high costs. Focus on early identification of patients at risk of developing chronic LBP has increased. The Keele Start Back Tool (SBT) is a questionnaire aiming at screening prognostic indicators in LBP patients, categorizing patients into risk-groups and guide treatment. The aim of this study was to explore the Norwegian version of the SBT with regard to reliability of the SBT-scoring and the screening ability in LBP patients in primary care physiotherapy...
May 31, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28559616/response-surface-optimization-of-extraction-protocols-to-obtain-phenolic-rich-antioxidant-from-sea-buckthorn-and-their-potential-application-into-model-meat-system
#13
Rajesh V Wagh, Manish K Chatli
In the present study, processing parameters for the extraction of phenolic rich sea buckthorn seed (SBTE) extract were optimised using response surface method and subjected for in vitro efficacy viz. total phenolic, ABTS, DPPH and SASA activity. The optimised model depicted MeOH as a solvent at 60% concentration level with a reaction time of 20 min and extracting temperature of 55 °C for the highest yield and total phenolic content. The efficacy of different concentration of obtained SBT was evaluated in raw ground pork as a model meat system on the basis of various physico-chemical, microbiological, sensory quality characteristics...
May 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28558660/pneumonia-caused-by-extensive-drug-resistant-acinetobacter-baumannii-among-hospitalized-patients-genetic-relationships-risk-factors-and-mortality
#14
Yu Jun Li, Chu Zhi Pan, Chang Quan Fang, Zhu Xiang Zhao, Hui Ling Chen, Peng Hao Guo, Zi Wen Zhao
BACKGROUND: The clonal spread of multiple drug-resistant Acinetobacter baumannii is an emerging problem in China. We analysed the molecular epidemiology of Acinetobacter baumanni isolates at three teaching hospitals and investigated the risk factors, clinical features, and outcomes of hospital-acquired pneumonia caused by extensive drug-resistant Acinetobacter baumannii (XDRAB) infection in Guangzhou, China. METHODS: Fifty-two A. baumannii isolates were collected...
May 30, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28533788/grapevine-subtilase-family-update-on-new-sequences-and-nomenclature-proposal
#15
Joana Figueiredo, Marisa Maia, Marta Sousa Silva, Andreia Figueiredo
In grapevine, serine peptidases from the subtilase family were recently associated to Plasmopara viticola resistance. This family in grapevine, first characterized in 2014, was re-analyzed last year and 82 subtilase genes were identified. However, in November of 2016, the National Center for Biotechnology Information database (NCBI) made a new public release of the grapevine genome annotation based on new sequencing data and better prediction algorithms. As a consequence, some gene annotations and lengths changed...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28524029/-predictive-value-of-left-ventricular-diastolic-dysfunction-on-mechanical-ventilation-weaning
#16
Hui Wang, Ming Ma, Desheng Chen, Gang Li, Shupeng Wang, Jingen Xia, Jun Duan
OBJECTIVE: To investigate the predictive value of left ventricular diastolic function on mechanical ventilation weaning in patients with left ventricular ejection fraction (LVEF) > 0.50. METHODS: A retrospective case control study was conducted. Sixty-five patients with LVEF > 0.50 undergoing mechanical ventilation for more than 48 hours admitted to surgery intensive care unit (ICU) of China-Japan Friendship Hospital from June 2014 to December 2016 were enrolled...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28468568/impact-of-low-dose-ketamine-on-the-usage-of-continuous-opioid-infusion-for-the-treatment-of-pain-in-adult-mechanically-ventilated-patients-in-surgical-intensive-care-units
#17
Jessica L Buchheit, Daniel Dante Yeh, Matthias Eikermann, Hsin Lin
BACKGROUND: Ketamine at subanesthetic doses has been shown to provide analgesic effects without causing respiratory depression and may be a viable option in mechanically ventilated patients to assist with extubation. The aim of this study was to evaluate the effects of low-dose ketamine on opioid consumption in mechanically ventilated adult surgical intensive care unit (ICU) patients. METHODS: A retrospective review of mechanically ventilated adult patients receiving low-dose ketamine continuous infusion (1-5 µcg/kg/min) for adjunctive pain control admitted to surgical ICUs was conducted...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28467631/from-structure-to-function-a-family-portrait-of-plant-subtilases
#18
REVIEW
Andreas Schaller, Annick Stintzi, Susana Rivas, Irene Serrano, Nina V Chichkova, Andrey B Vartapetian, Dana Martínez, Juan J Guiamét, Daniela J Sueldo, Renier A L van der Hoorn, Vicente Ramírez, Pablo Vera
I. II. III. IV. V. References SUMMARY: Subtilases (SBTs) are serine peptidases that are found in all three domains of life. As compared with homologs in other Eucarya, plant SBTs are more closely related to archaeal and bacterial SBTs, with which they share many biochemical and structural features. However, in the course of evolution, functional diversification led to the acquisition of novel, plant-specific functions, resulting in the present-day complexity of the plant SBT family. SBTs are much more numerous in plants than in any other organism, and include enzymes involved in general proteolysis as well as highly specific processing proteases...
May 3, 2017: New Phytologist
https://www.readbyqxmd.com/read/28467468/model-based-classification-of-cpt-data-and-automated-lithostratigraphic-mapping-for-high-resolution-characterization-of-a-heterogeneous-sedimentary-aquifer
#19
Bart Rogiers, Dirk Mallants, Okke Batelaan, Matej Gedeon, Marijke Huysmans, Alain Dassargues
Cone penetration testing (CPT) is one of the most efficient and versatile methods currently available for geotechnical, lithostratigraphic and hydrogeological site characterization. Currently available methods for soil behaviour type classification (SBT) of CPT data however have severe limitations, often restricting their application to a local scale. For parameterization of regional groundwater flow or geotechnical models, and delineation of regional hydro- or lithostratigraphy, regional SBT classification would be very useful...
2017: PloS One
https://www.readbyqxmd.com/read/28438880/testicular-dose-during-prophylaxis-of-heterotopic-ossification-with-radiation-therapy
#20
Waleed F Mourad, John K Ma, Satyaseelan Packianathan, Weisi Yan, Sherif G Shaaban, Edward M Marchan, Lamiaa E Abdallah, Rei He, Paul N Mobit, Chunli Claus Yang, Srinivasan Vijayakumar
AIM: A single-institution, retrospective study was performed to investigate potential techniques to minimize radiation exposure to the testicles during heterotopic ossification (HO) prophylaxis. We report the impact of split-beam technique (SBT) and different photon energies on the total dose of radiation received by the testicles during prophylaxis of HO. MATERIALS AND METHODS: Between 2008 and 2010, we identified 64 patients with traumatic acetabular fractures who underwent surgery followed by radiation therapy (RT) without testicular shielding...
May 2017: In Vivo
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