keyword
MENU ▼
Read by QxMD icon Read
search

SBT

keyword
https://www.readbyqxmd.com/read/28803993/nanoemulsion-formulation-of-a-novel-taxoid-dha-sbt-1214-inhibits-prostate-cancer-stem-cell-induced-tumor-growth
#1
Gulzar Ahmad, Rana El Sadda, Galina Botchkina, Iwao Ojima, James Egan, Mansoor Amiji
The main aim of this study was to evaluate the therapeutic efficacy of an oil-in-water nanoemulsion formulation encapsulating DHA-SBT-1214, a novel omega-3 fatty acid conjugated taxoid prodrug, against prostate cancer stem cells. Nanoemulsions of DHA-SBT-1214 (NE-DHA-SBT-1214) were prepared and characterized. In vitro delivery efficiency and cytotoxicity of NE-DHA-SBT-1214 was compared with solution formulation in PPT2 cells. In vivo studies included analysis of comparative efficacy of NE-DHA-SBT-1214 with Abraxane(®) and placebo nanoemulsions as well as post-treatment alternations in clonogenic and sphere-forming capabilities of the tumor cells...
August 11, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28792380/evaluation-of-the-bd-max-enteric-parasite-panel-for-the-detection-of-cryptosporidium-parvum-hominis-giardia-duodenalis-and-entamoeba-histolytica
#2
Michael D Perry, Sally A Corden, P Lewis White
PURPOSE: Conventional laboratory detection methods for gastrointestinal parasites are time consuming, require considerable technical expertise and may suffer from poor analytical sensitivity. This study sought to evaluate the automated BD MAX Enteric Parasite Panel (EPP) for the detection of Cryptosporidium parvum/hominis, Entamoeba histolytica and Giardia duodenalis.Methodolgy. A total of 104 known positive samples (43 Cryptosporidium parvum/hominis and 61 G. duodenalis), 15 simulated samples (E...
August 10, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28790149/evaluation-of-endotracheal-tube-scraping-on-airway-resistance
#3
J Brady Scott, Meagan N Dubosky, David L Vines, Adewunmi S Sulaiman, Kyle R Jendral, Gagan Singh, Ankeet Patel, Carl A Kaplan, David P Gurka, Robert A Balk
BACKGROUND: Spontaneous breathing trials (SBTs) are used to assess the readiness for discontinuation of mechanical ventilation. When airway resistance (Raw) is elevated, the imposed work of breathing can lead to prolongation of mechanical ventilation. Biofilm and mucus build-up within the endotracheal tube (ETT) can increase Raw. Scraping the ETT can remove the biofilm build-up and decrease mechanical Raw. The primary aim of this study was to evaluate the impact of ETT scraping on Raw...
August 8, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28774355/funding-quality-pre-kindergarten-slots-with-philadelphia-s-new-sugary-drink-tax-simulating-effects-of-using-an-excise-tax-to-address-a-social-determinant-of-health
#4
Brent A Langellier, Félice Lê-Scherban, Jonathan Purtle
OBJECTIVE: Philadelphia passed a 1·5-cent-per-ounce sweetened beverage tax (SBT). Revenue will fund 10 000 quality pre-kindergarten slots for poor children. It is imperative to understand how revenue from SBT can be used to fund programmes to address education and other social determinants of health. The objective of the present study was to simulate quality pre-kindergarten attendance, educational achievement and sugar-sweetened beverage (SSB) consumption among Philadelphia children and adolescents under six intervention scenarios: (i) no intervention; (ii) 10 000 additional quality pre-kindergarten slots; (iii) a 1·5-cent-per-ounce SBT; (iv) expanded pre-kindergarten and 1·5-cent-per-ounce SBT; (v) a 3-cent-per-ounce SBT; and (vi) expanded pre-kindergarten and 3-cent-per-ounce SBT...
August 4, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28757772/using-high-resolution-human-leukocyte-antigen-typing-of-11-423-randomized-unrelated-individuals-to-determine-allelic-varieties-deduce-probable-human-leukocyte-antigen-haplotypes-and-observe-linkage-disequilibria-between-human-leukocyte-antigen-b-and-c-and-human
#5
Kuo-Liang Yang, Hsee-Bin Chen
OBJECTIVE: We report here the human leukocyte antigen (HLA) allelic variety and haplotype composition in a cohort of the Taiwanese Chinese population and their patterns of linkage disequilibria on HLA-B: HLA-C alleles and HLA-DRB1: HLA-DQB1 alleles at a high-resolution level. MATERIALS AND METHODS: Peripheral whole blood from 11,423 Taiwanese Chinese unrelated individuals was collected in acid citrate dextrose. Genomic DNA was extracted using the QIAamp DNA Blood Mini Kit...
April 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28752065/serous-borderline-tumor-of-the-testis-and-associated-magnetic-resonance-imaging-findings
#6
Alan Hsieh, Mitchell Miller, Wenlei He, David Shin
Serous borderline tumor (SBT) of the testis is a rare, ovarian epithelial-type tumor of the testis. We present a case of SBT after radical orchiectomy in a 59-year-old man who had 3-month progressive enlargement of his right hemi-scrotum, negative testicular tumor markers and scrotal ultrasound equivocal for malignancy. Magnetic resonance imaging (MRI) of the pelvis was obtained to aid with evaluation and showed marked hyperintensity on T2-weighted images with frond-like nodular peripheral enhancement within right testis mass...
September 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28743339/-predictive-value-of-ultrasonic-diaphragm-thickening-fraction-on-successful-weaning-for-patients-with-myasthenia-gravis-crisis
#7
Qiang Sun, Feng Shan, Hai Dong, Yan Jiang, Yongmei Sun, Yunbo Sun
OBJECTIVE: To confirm the predictive value of diaphragm thickening fraction (DTF) on successful weaning by bedside ultrasound in patients with myasthenia gravis crisis. METHODS: A prospective study was conducted. The patients with myasthenia gravis crisis undergoing mechanical ventilation admitted to Department of Critical Care Medicine of the Affiliated Hospital of Qingdao University from March 2015 to February 2017 were enrolled. All patients underwent a low level pressure support mode of spontaneous breathing test (SBT), and rapid shallow breathing index (RSBI) was recorded...
July 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28720673/challenges-with-implementation-of-a-respiratory-therapist-driven-protocol-of-spontaneous-breathing-trials-in-the-pediatric-icu
#8
Conrad Krawiec, Dale Carl, Christy Stetter, Lan Kong, Gary D Ceneviva, Neal J Thomas
BACKGROUND: Timely ventilator liberation is crucial in the pediatric ICU. In many pediatric ICUs, the decision to initiate weaning is driven by the physician, which may lead to delays in ventilator liberation. The objectives of this quality improvement project were to develop and implement a respiratory therapist (RT)-led protocol for screening for spontaneous breathing trial (SBT) readiness, to test protocol feasibility, and to evaluate its impact on SBT timing. METHODS: A retrospective chart review was performed on all intubated patients in the pediatric ICU for 18 months prior to protocol institution...
July 18, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28710577/detection-of-small-bowel-tumours-with-ct-enteroclysis-using-carbon-dioxide-and-virtual-enteroscopy-a-preliminary-study
#9
Anthony Dohan, Mourad Boudiaf, Xavier Dray, Elia Samaha, Christophe Cellier, Marine Camus, Clarisse Eveno, Raphael Dautry, Philippe Soyer
PURPOSE: The aim of this prospective study was to evaluate the feasibility, tolerance and performance of virtual enteroscopy (VE) using carbon dioxide for small-bowel distension in patients with suspected small-bowel tumours (SBTs). PATIENTS AND METHODS: After IRB approval, 17 patients with suspected SBTs were prospectively included. Radiation dose was compared to 34 matched patients (2 for 1) for age, gender and body weight, who had undergone CT-enteroclysis with neutral contrast (CTE)...
July 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28709881/can-primary-care-for-back-and-or-neck-pain-in-the-netherlands-benefit-from-stratification-for-risk-groups-according-to-the-start-back-tool-classification
#10
Jasper D Bier, Janneke J W Sandee-Geurts, Raymond W J G Ostelo, Bart W Koes, Arianne P Verhagen
OBJECTIVE: To evaluate whether current Dutch primary-care clinicians offer tailored treatment to patients with lower-back pain (LBP) or neck pain (NP) according to their risk stratification, based on the Keele STarT (Subgroup Targeted Treatment) Back-Screening Tool (SBT). DESIGN: Prospective cohort study with 3 month follow-up SETTING: Primary care PARTICIPANTS: General practitioners (GPs) and physiotherapists (PTs) included patients with non-specific LBP and/or NP...
July 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28707742/intramolecular-locked-dithioalkylbithiophene-based-semiconductors-for-high-performance-organic-field-effect-transistors
#11
Sureshraju Vegiraju, Bo-Chin Chang, Pragya Priyanka, Deng-Yi Huang, Kuan-Yi Wu, Long-Huan Li, Wei-Chieh Chang, Yi-Yo Lai, Shao-Huan Hong, Bo-Chun Yu, Chien-Lung Wang, Wen-Jung Chang, Cheng-Liang Liu, Ming-Chou Chen, Antonio Facchetti
New 3,3'-dithioalkyl-2,2'-bithiophene (SBT)-based small molecular and polymeric semiconductors are synthesized by end-capping or copolymerization with dithienothiophen-2-yl units. Single-crystal, molecular orbital computations, and optical/electrochemical data indicate that the SBT core is completely planar, likely via S(alkyl)⋯S(thiophene) intramolecular locks. Therefore, compared to semiconductors based on the conventional 3,3'-dialkyl-2,2'-bithiophene, the resulting SBT systems are planar (torsional angle <1°) and highly π-conjugated...
July 14, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28704815/relaxation-rate-of-the-respiratory-muscles-and-prediction-of-extubation-outcome-in-prematurely-born-infants
#12
Theodore Dassios, Ourania Kaltsogianni, Anne Greenough
BACKGROUND: Accurate prediction of extubation outcome could result in a significant reduction of respiratory morbidity in premature neonates. OBJECTIVES: To assess whether the respiratory muscle time constant of relaxation (τ) predicted extubation outcome in mechanically ventilated, premature infants. METHODS: Forty-six mechanically ventilated infants with a median gestational age of 26 (interquartile range [IQR] 25-29) weeks were prospectively studied...
July 14, 2017: Neonatology
https://www.readbyqxmd.com/read/28700429/mucosal-proliferations-in-completely-examined-fallopian-tubes-accompanying-ovarian-low-grade-serous-tumors-neoplastic-precursor-lesions-or-normal-variants-of-benign-mucosa
#13
Rebecca J Wolsky, Matt A Price, Charles J Zaloudek, Joseph T Rabban
Malignant transformation of the fallopian tube mucosa, followed by exfoliation of malignant cells onto ovarian and/or peritoneal surfaces, has been implicated as the origin of most pelvic high-grade serous carcinoma. Whether a parallel pathway exists for pelvic low-grade serous tumors [ovarian serous borderline tumor (SBT) and low-grade serous carcinoma (LGSC)] remains to be fully elucidated. The literature is challenging to interpret due to variation in the diagnostic criteria and terminology for cytologically low-grade proliferations of the fallopian tube mucosa, as well as variation in fallopian tube specimen sampling...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28697778/electrical-impedance-tomography-for-predicting-failure-of-spontaneous-breathing-trials-in-patients-with-prolonged-weaning
#14
Johannes Bickenbach, Michael Czaplik, Mareike Polier, Gernot Marx, Nikolaus Marx, Michael Dreher
BACKGROUND: Spontaneous breathing trials (SBTs) on a T-piece can be difficult in patients with prolonged weaning because of remaining de-recruitment phenomena and/or insufficient ventilation. There is no clinically established method existent other than experience for estimating whether an SBT is most probably beneficial. Electrical impedance tomography (EIT) is a clinical useful online monitoring technique during mechanical ventilation, particularly because it enables analysis of effects of regional ventilation distribution...
July 12, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28693057/-the-value-of-the-excursion-of-diaphragm-tested-by-ultrosonography-to-predict-weaning-from-mechanical-ventilation-in-icu-patients
#15
L X Liu, D Su, Z J Hu
Objective: To evaluate the excursion of the diaphragm and analyze the value in predicting weaning from mechanical ventilation in intensive care unit patients. Methods: The patients with mechanical ventilation (>48 hours) in ICU at Hebei Forth Medical University Hospital from June 2014 to December were classified into a success group or a failure group according to the weaning outcome. T-piece spontaneous breathing (SBT), airway occlusion pressure at 0.1 sec (P(0.1)) and maximal inspiratory pressure (MIP), rapid shallow breathing index (RSBI) and P(0...
July 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28659467/motor-learning-in-a-complex-balance-task-and-associated-neuroplasticity-a-comparison-between-endurance-athletes-and-non-athletes
#16
Oliver Seidel, Daniel Carius, Rouven Kenville, Patrick Ragert
Studies suggested that motor expertise is associated with functional and structural brain alterations, which positively affect sensorimotor performance and learning capabilities. The purpose of the present study was to unravel differences in motor skill learning and associated functional neuroplasticity between endurance athletes (EA) and non-athletes (NA). For this purpose, participants had to perform a multimodal balance task (MBT) training on two sessions which were separated by one week. Before and after MBT-training, a static balance task (SBT) had to be performed...
June 28, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28651862/severe-impacts-of-brown-tides-caused-by-sargassum-spp-on-near-shore-caribbean-seagrass-communities
#17
Brigitta I van Tussenbroek, Héctor A Hernández Arana, Rosa E Rodríguez-Martínez, Julio Espinoza-Avalos, Hazel M Canizales-Flores, Carlos E González-Godoy, M Guadalupe Barba-Santos, Alejandro Vega-Zepeda, Ligia Collado-Vides
From mid-2014 until the end of 2015, the Mexican Caribbean coast experienced a massive influx of drifting Sargassum spp. that accumulated on the shores, resulting in build-up of decaying beach-cast material and near-shore murky brown waters (Sargassum-brown-tides, Sbt). The effects of Sbt on four near-shore waters included reduction in light, oxygen (hypoxia or anoxia) and pH. The monthly influx of nitrogen, and phosphorus by drifting Sargassum spp. was estimated at 6150 and 61kgkm(-1) respectively, resulting in eutrophication...
June 23, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28645964/the-predictive-value-of-serial-changes-in-diaphragm-function-during-the-spontaneous-breathing-trial-for-weaning-outcome-a-study-protocol
#18
Pengmin Zhou, Zhongheng Zhang, Yucai Hong, Huabo Cai, Hui Zhao, Peifeng Xu, Yiming Zhao, Shengping Lin, Xuchang Qin, JiaWei Guo, Yun Pan, Junru Dai
INTRODUCTION: There is a variety of tools being used in clinical practice for the prediction of weaning success from mechanical ventilation. However, their diagnostic performances are less than satisfactory. The purpose of this study is to investigate the value of serial changes in diaphragm function measured by ultrasound during the spontaneous breathing trial (SBT) as a weaning predictor. METHODS AND ANALYSIS: This is a prospective observational study conducted in a 10-bed medical emergency intensive care unit (EICU) in a university-affiliated hospital...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28644962/validity-and-reproducibility-of-the-modified-start-back-tool-dutch-version-for-patients-with-neck-pain-in-primary-care
#19
Jasper D Bier, Raymond W J G Ostelo, Bart W Koes, Arianne P Verhagen
OBJECTIVE: To evaluate the reliability and validity of the Dutch version of the STarT Back screening Tool (SBT), for patients with neck pain. METHODS: We modified the SBT to fit patients with neck pain. General practitioners and physiotherapists included patients who completed both a baseline and a follow-up questionnaire at 3 days and 3 months, respectively. The construct validity was assessed using Pearson's correlation between the SBT and the reference questionnaires...
June 15, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28642919/correlation-between-antioxidant-activity-and-bonding-strength-on-bleached-enamel
#20
Hellen Caroliny De Carvalho, Ricardo Danil Guiraldo, Regina Célia Poli-Frederico, Sandra Mara Maciel, Sandra Kiss Moura, Murilo Baena Lopes, Sandrine Bittencourt Berger
Objective: This study used the 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) method to evaluate the percentage of antioxidant activity (%AA) of green tea (GT) and sodium ascorbate (SA) gel in three concentrations (10%, 20% and 30%), and the influence of these concentrations on the microshear bond strength (μ-SBT) values of bleached enamel, using 10% carbamide peroxide (CP). Materials and methods: Eighty intact third molars were selected to perform the μ-SBT test, and were randomly divided into eight experimental groups: G1: positive control - no treatment; G2: negative control - bleached with CP; G3: PC +10% GT; G4: PC +20% GT; G5: PC +30% GT; G6: PC +10% SA; G7: PC +20% SA and G8: PC +30% SA...
December 2016: Acta Biomaterialia Odontologica Scandinavica
keyword
keyword
45718
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"