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Urinary tract infection elderly

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https://www.readbyqxmd.com/read/28274327/antipsychotic-drug-use-associated-with-urinary-tract-infections-in-older-women
#1
Astrid M van Strien, Patrick C Souverein, Carolina Karen J P W Keijsers, Eibert R Heerdink, Hieronymus Jeroen J Derijks, Rob J van Marum
OBJECTIVES: Antipsychotic drugs are frequently prescribed to elderly patients, but they are associated with serious adverse effects. The objective of the current study was to investigate the association between use of antipsychotics by elderly women and the risk of urinary tract infections (UTIs). COHORT STUDY SETTING: Dispensing data were obtained from the PHARMO Database Network for the period 1998-2008. PARTICIPANTS: Ambulatory Dutch women (≥65 years) with current and past use of antipsychotics...
April 2017: Maturitas
https://www.readbyqxmd.com/read/28269432/illumination-and-device-independence-for-colorimetric-detection-of-urinary-biomarkers-with-smartphone
#2
Haakon Karisen, Tao Dong
Diaper wearing elderly with functional impairments and/or incontinence is at high risk of contracting urinary tract infections. Nurses struggle with collection of urine samples for analysis. Therefore, a smartphone application is under development as a rapid screening device to work in conjunction with a colorimetric diaper assay that collects and tests urine within a diaper. The focus of this work is to make a practical and useful tool that medical personnel (the user) can use for rapid screening on patients in the field, only with a smartphone and assay available...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28266340/evaluation-of-antibiotic-prescriptions-for-urinary-tract-infections-in-a-geriatric-rehabilitation-unit
#3
Hind Afekouh, Patricia Baune, Diane De Falvelly, Fatima Guermah, Saïda Ghitri, Nicole Haber
Prescription of antibiotic in elderly patients must follow guidelines. to study the quality of antibiotic prescriptions for urinary tract infections (UTI) in the geriatric rehabilitation unit. Over a four-month period, all the antibiotics treatments prescribed for UTI in the rehabilitation ward were analyzed prospectively by medical experts and confronted with the recommendations of the local antibiotic guidelines. The methodology was based on Gyssens' algorithm. Treatments were considered appropriate if indication, choice of the molecule, duration and dose were approved by the experts, unnecessary if the indication was incorrect, and inappropriate in all other cases...
March 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28227678/illumination-and-device-independence-for-colorimetric-detection-of-urinary-biomarkers-with-smartphone
#4
Haakon Karisen, Tao Dong, Haakon Karisen, Tao Dong, Tao Dong
Diaper wearing elderly with functional impairments and/or incontinence is at high risk of contracting urinary tract infections. Nurses struggle with collection of urine samples for analysis. Therefore, a smartphone application is under development as a rapid screening device to work in conjunction with a colorimetric diaper assay that collects and tests urine within a diaper. The focus of this work is to make a practical and useful tool that medical personnel (the user) can use for rapid screening on patients in the field, only with a smartphone and assay available...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28195824/sleep-surgery-in-the-elderly
#5
Christopher J Gouveia, John D Cramer, Stanley Yung-Chuan Liu, Robson Capasso
Objective Assess the frequency and nature of postoperative complications following sleep surgery. Examine these issues specifically in elderly patients to provide guidance for their perioperative care. Study Design Retrospective cohort study. Setting American College of Surgeons National Surgical Quality Improvement Program. Methods We identified patients with obstructive sleep apnea undergoing sleep surgery procedures from 2006 to 2013 in the American College of Surgeons National Surgical Quality Improvement Program, a multi-institutional outcomes program designed to improve surgical quality...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28107773/safety-and-effectiveness-of-tofogliflozin-in-elderly-japanese-patients-with-type-2-diabetes-mellitus-a-post-marketing-study-j-step-el-study
#6
Kazunori Utsunomiya, Naoki Shimmoto, Masayuki Senda, Yuji Kurihara, Ryoji Gunji, Shoko Fujii, Seigo Kakiuchi, Hisataka Fujiwara, Hiroyuki Kameda, Masahiro Tamura, Kohei Kaku
AIMS/INTRODUCTION: While sodium glucose cotransporter 2 inhibitors are a promising treatment for type 2 diabetes mellitus, they are associated with concerns about specific adverse drug reactions. We conducted a 1-year post-marketing study of tofogliflozin, a novel agent in this class, in Japanese elderly patients with type 2 diabetes mellitus. MATERIALS AND METHODS: This was a prospective, observational, and multicenter post-marketing study conducted in the context of routine clinical practice...
January 20, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28105986/canagliflozin-dapagliflozin-and-empagliflozin-monotherapy-for-treating-type-2-diabetes-systematic-review-and-economic-evaluation
#7
Rhona Johnston, Olalekan Uthman, Ewen Cummins, Christine Clar, Pamela Royle, Jill Colquitt, Bee Kang Tan, Andrew Clegg, Saran Shantikumar, Rachel Court, J Paul O'Hare, David McGrane, Tim Holt, Norman Waugh
BACKGROUND: Most people with type 2 diabetes are overweight, so initial treatment is aimed at reducing weight and increasing physical activity. Even modest weight loss can improve control of blood glucose. If drug treatment is necessary, the drug of first choice is metformin. However, some people cannot tolerate metformin, which causes diarrhoea in about 10%, and it cannot be used in people with renal impairment. This review appraises three of the newest class of drugs for monotherapy when metformin cannot be used, the sodium-glucose co-transporter 2 (SGLT2) inhibitors...
January 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28077671/impact-of-long-term-care-facility-residence-on-the-antibiotic-resistance-of-urinary-tract-escherichia-coli-and-klebsiella
#8
Alicia Rosello, Andrew C Hayward, Susan Hopkins, Carolyne Horner, Dean Ironmonger, Peter M Hawkey, Sarah R Deeny
BACKGROUND: Long-term care facilities (LTCFs) are thought to be important reservoirs of antimicrobial-resistant (AMR) bacteria; however, there is no routine surveillance of resistance in LTCF residents, or large population-based studies comparing AMR in LTCFs with the community, so the relative burden of AMR in LTCFs remains unknown. OBJECTIVES: To compare the frequency of antibiotic resistance of urinary tract bacteria from residents of LTCFs for the elderly and adults aged 70 years or older living in the community...
January 10, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28051247/supplementation-with-high-titer-cranberry-extract-anthocran%C3%A2-for-the-prevention-of-recurrent-urinary-tract-infections-in-elderly-men-suffering-from-moderate-prostatic-hyperplasia-a-pilot-study
#9
A Ledda, G Belcaro, M Dugall, B Feragalli, A Riva, S Togni, L Giacomelli
OBJECTIVE: Recently, cranberry extracts have been tested as a nutritional supplementation in the prevention of lower urinary tract symptoms (LUTS) as well as recurrent urinary tract infections (UTIs) in subjects at risk, with mixed results. However, evidence of efficacy should be considered only for well-characterized and standardized products in a more selected study population. Moreover, the efficacy of these interventions in elderly must be further investigated. The aim of this pilot, registry study was to evaluate the prophylactic effects of an oral supplementation containing a highly concentrated and standardized cranberry extract reproducing the natural total profile of cranberry fruits, in elderly men with benign prostatic hyperplasia (BPH), suffering from recurrent UTIs, over a 2-months follow-up...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28040259/postoperative-fever-after-hemiarthroplasty-in-elderly-patients-over-70-years-of-age-with-displaced-femoral-neck-fracture-necessity-of-routine-workup
#10
Je-Hyun Yoo, Ki-Tae Kim, Tae-Young Kim, Ji-Hyo Hwang, Jun-Dong Chang
OBJECTIVES: Displaced femoral neck fracture in elderly patients has been treated with hemiarthroplasty as the treatment of choice. Fever following HA is common in these elderly patients. The aim of this study was to determine which post-HA fever workup could be beneficial in this group of patients. METHODS: A total of 272 consecutive patients aged ≥70 years undergoing HA for displaced femoral neck fracture were retrospectively investigated. Postoperative fever (POF) was defined as any recorded body temperature ≥38°C in the early postoperative period...
February 2017: Injury
https://www.readbyqxmd.com/read/28017477/executive-summary-of-the-diagnosis-and-treatment-of-urinary-tract-infection-guidelines-of-the-spanish-society-of-clinical-microbiology-and-infectious-diseases-seimc
#11
Marina de Cueto, Luis Aliaga, Juan-Ignacio Alós, Andres Canut, Ibai Los-Arcos, Jose Antonio Martínez, Jose Mensa, Vicente Pintado, Dolors Rodriguez-Pardo, Jose Ramon Yuste, Carles Pigrau
Most urinary tract infections (UTI) are uncomplicated infections occurring in young women. An extensive evaluation is not required in the majority of cases, and they can be safely managed as outpatients with oral antibiotics. Escherichia coli is by far the most common uropathogen, accounting for >80% of all cases. Other major clinical problems associated with UTI include asymptomatic bacteriuria, and patients with complicated UTI. Complicated UTIs are a heterogeneous group associated with conditions that increase the risk of acquiring infection or treatment failure...
December 22, 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27989724/frailty-is-associated-with-morbidity-in-adults-undergoing-elective-anterior-lumbar-interbody-fusion-alif-surgery
#12
Kevin Phan, Jun S Kim, Nathan J Lee, Sulaiman Somani, John Di Capua, Parth Kothari, Dante Leven, Samuel K Cho
BACKGROUND CONTEXT: Prior studies have suggested no significant differences in functional status and postoperative complications of elderly versus nonelderly patients undergoing posterior lumbar interbody fusion; however, similar studies have not been comprehensively investigated in the setting of anterior lumbar interbody fusion (ALIF). PURPOSE: The objective was to quantify the ability of the modified Frailty Index (mFI) to predict postoperative events in patients undergoing ALIF...
October 27, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27936166/increased-age-but-not-parity-predisposes-to-higher-bacteriuria-burdens-due-to-streptococcus-urinary-tract-infection-and-influences-bladder-cytokine-responses-which-develop-independent-of-tissue-bacterial-loads
#13
Matthew J Sullivan, Alison J Carey, Sophie Y Leclercq, Chee K Tan, Glen C Ulett
Streptococcus agalactiae causes urinary tract infection (UTI) in pregnant adults, non-pregnant adults, immune-compromised individuals and the elderly. The pathogenesis of S. agalactiae UTI in distinct patient populations is poorly understood. In this study, we used murine models of UTI incorporating young mice, aged and dam mice to show that uropathogenic S. agalactiae causes bacteriuria at significantly higher levels in aged mice compared to young mice and this occurs coincident with equivalent levels of bladder tissue colonisation at 24 h post-infection (p...
2016: PloS One
https://www.readbyqxmd.com/read/27922910/impact-of-medicare-s-nonpayment-program-on-hospital-acquired-conditions
#14
Caroline P Thirukumaran, Laurent G Glance, Helena Temkin-Greener, Meredith B Rosenthal, Yue Li
BACKGROUND: Medicare's Nonpayment Program of 2008 (hereafter called Program) withholds hospital reimbursement for costs related to hospital-acquired conditions (HACs). Little is known whether a hospital's Medicare patient load [quantified by the hospital's Medicare utilization ratio (MUR), which is the proportion of inpatient days financed by Medicare] influences its response to the Program. OBJECTIVE: To determine whether the Program was associated with changes in HAC incidence, and whether this association varies across hospitals with differential Medicare patient load...
December 5, 2016: Medical Care
https://www.readbyqxmd.com/read/27913316/actinotignum-schaalii-subcutaneous-abscesses-in-a-patient-with-hidradenitis-suppurativa-case-report-and-literature-review
#15
REVIEW
Sofia Maraki, George Evangelou, Dimitra Stafylaki, Efstathia Scoulica
Actinotignum schaalii (formerly Actinobaculum schaalii) is a Gram-positive, facultative anaerobic rod that is typically involved in urinary tract infections in elderly patients or those with underlying urological pathologies. In contrast, abscess formation caused by A. schaalii is very rare. We present a case of multiple abscesses in the perineal area in a young patient with hidradenitis suppurativa associated with A. schaalii and Prevotella melaninogenica and review the relevant literature on the topic.
November 29, 2016: Anaerobe
https://www.readbyqxmd.com/read/27889591/adverse-events-and-treatment-discontinuations-of-antimuscarinics-for-the-treatment-of-overactive-bladder-in-older-adults-a-systematic-review-and-meta-analysis
#16
REVIEW
Scott Martin Vouri, Clark D Kebodeaux, Paul M Stranges, Besu F Teshome
INTRODUCTION: Antimuscarinics should be used with caution in older adults with overactive bladder (OAB) due to anticholinergic adverse events (AEs). Systematic reviews and meta-analyses (SRMAs) have analyzed safety-related outcomes but have not specified risk in the elderly, the population at highest risk for AEs. The aim of this review is to explore and evaluate AEs and treatment discontinuations in adults 65 or older taking antimuscarinics for OAB. METHODS: Keywords were searched in MEDLINE, EMBASE, SCOPUS, and Cochrane Central Register for Controlled Trials...
March 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27843874/unusual-complication-of-prolonged-indwelling-urinary-catheter-iatrogenic-hypospadias
#17
Gunjan Garg, Vishal Baghele, Naveen Chawla, Atul Gogia, Atul Kakar
Long-time urethral catheterization may be responsible for various complications such as urethral stricture, urethral fracture, urinary tract infections, and hypospadias. Hypospadias is the most common congenital anomaly of male external genitalia. However, urethral catheter-induced iatrogenic hypospadias is a rare entity. In this article, we describe a case of an elderly male who was found to have iatrogenic hypospadias 2 months after urinary catheterization.
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27788499/assessment-of-fosfomycin-for-complicated-or-multidrug-resistant-urinary-tract-infections-patient-characteristics-and-outcomes
#18
Stephanie E Giancola, Monica V Mahoney, Michael D Hogan, Brian R Raux, Christopher McCoy, Elizabeth B Hirsch
BACKGROUND: Bacterial resistance among uropathogens is on the rise and has led to a decreased effectiveness of oral therapies. Fosfomycin tromethamine (fosfomycin) is indicated for uncomplicated urinary tract infections (UTIs) and displays in vitro activity against multidrug-resistant (MDR) isolates; however, clinical data assessing fosfomycin for the treatment of complicated or MDR UTIs are limited. METHODS: We conducted a retrospective evaluation of patients who received ≥1 dose of fosfomycin between January 2009 and September 2015 for treatment of a UTI...
2017: Chemotherapy
https://www.readbyqxmd.com/read/27777243/antimicrobial-susceptibility-of-long-term-care-facility-and-general-practice-urine-samples-in-patients-65-years-and-older-an-observational-study
#19
Aoife Fleming, Louise Barry, Stephen Byrne, Michael Prentice
BACKGROUND: Antimicrobial resistance in long-term care facilities (LTCFs) poses a risk to elderly residents. The aim of this observational study was to investigate recent patterns of antimicrobial susceptibility in urine samples submitted to the Microbiology Laboratory at Cork University Hospital (CUH) from LTCFs in the greater Cork region. The antimicrobial susceptibilities of LTCF and General Practitioner (GP) urine samples sent to CUH, for patients aged over 65 years of age, were compared...
October 24, 2016: European Journal of Public Health
https://www.readbyqxmd.com/read/27753066/diagnosis-of-elder-abuse-in-u-s-emergency-departments
#20
Christopher S Evans, Katherine M Hunold, Tony Rosen, Timothy F Platts-Mills
OBJECTIVES: To estimate the proportion of visits to U.S. emergency departments (EDs) in which a diagnosis of elder abuse is reached using two nationally representative datasets. DESIGN: Retrospective cross-sectional analysis. SETTING: U.S. ED visits recorded in the 2012 Nationwide Emergency Department Sample (NEDS) or the 2011 National Hospital Ambulatory Medical Care Survey (NHAMCS). PARTICIPANTS: All ED visits of individuals aged 60 and older...
January 2017: Journal of the American Geriatrics Society
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