keyword
https://read.qxmd.com/read/38510368/anticoagulation-management-in-elderly-patients-with-proximal-femur-fractures%C3%A2-overview-of-current-concepts
#1
REVIEW
Yasmin Youssef, Anna K I M Dietrich, Annika Hättich
OBJECTIVES: Proximal femur fractures (PFF) are common injuries in elderly patients and can have considerable effects on their quality of life, morbidity, and mortality. Due to pre-existing comorbidities, the prevalence of anticoagulated patients is increasing. The right timing for surgery and perioperative anticoagulation treatment remains controversial. CONTENT: This overview aims to summarize current practices in the pre- and postoperative anticoagulation management and the recommended time to surgery in elderly patients with PFF...
December 2023: Innovative Surgical Sciences
https://read.qxmd.com/read/38476736/infective-endocarditis-due-to-citrobacter-koseri-following-testicular-trauma-case-report-and-literature-review
#2
Julian Orlando Casallas-Barrera, Claudia Marcela Poveda-Henao, Karen Andrea Mantilla-Viviescas, Edwin Silva-Monsalve
Infective endocarditis (IE) is a condition with low prevalence but high mortality rates within intensive care units. Microbiologically, most cases are attributed to Gram-positive cocci, while Gram-negative bacilli are less commonly involved. This case report describes a patient with IE caused by Citrobacter koseri (C. koseri) with secondary bacteremia due to blunt testicular trauma and epididymitis. We conducted a review of the literature to assess the clinical and associated risk factors of this underreported condition...
2024: Therapeutic Advances in Infectious Disease
https://read.qxmd.com/read/38457596/chronic-infective-arthritis-with-osteomyelitis-of-the-ankle-due-to-pseudomonas-aeruginosa-infection-in-a-middle-age-woman-a-rare-causative-pathogen-requiring-vigilance
#3
JOURNAL ARTICLE
Chien-Liang Chen, Tai-Kuang Chao, Fu-Chiang Yeh, Ching-Lan Wu, Ching-Hsun Wang
RATIONALE: Pseudomonas aeruginosa-induced septic arthritis is a relatively uncommon phenomenon. It has been documented in children with traumatic wounds, young adults with a history of intravenous drug use, and elderly patients with recent urinary tract infections or surgical procedures. PATIENT CONCERNS: Fifty-nine year-old female had no reported risk factors. The patient sought medical attention due to a 6-month history of persistent pain and swelling in her right ankle...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38449975/intensive-care-management-of-an-adult-patient-with-rare-chilaiditi-syndrome-presenting-as-abdominal-breathing-a-case-report
#4
Gulseren Yilmaz, Kubra Mentese, Pelin Kilic Erol, Bedih Balkan, Ummihan Topal
Chilaiditi syndrome (CS) is an uncommon case of the asymptomatic radiographic finding of an intestinal loop between the liver and the diaphragm. The most crucial phases in the diagnosis process are a thorough physical examination and precise imaging, particularly in challenging disorders such as CS. The presence of free air under the right hemidiaphragm in this syndrome, the diagnosis of which is based on radiographic imaging, might direct the start of treatment without the need for surgical intervention. An 86-year-old man, with asthma and chronic obstructive pulmonary disease (COPD) was checked out in our hospital's emergency department (ED) after experiencing nausea and vomiting...
February 2024: Curēus
https://read.qxmd.com/read/38442961/wunderlich-syndrome-in-a-patient-with-pyelonephritis
#5
JOURNAL ARTICLE
Joshua Chin Howe Chia, Chiara Jiamin Chong, Yan Rong Yong, Poh Yong Tan
An elderly female patient with left pyelonephritis developed worsening left flank pain, hypotension and a drop in haemoglobin (Hb) from 97 g/L to 67g/L on the third day of her admission. There was no recent trauma, history of coagulopathy or risk factors for renal malignancy or vascular disease.A contrasted CT scan of the kidneys revealed a 3.8 cm left renal subcapsular haematoma with no active contrast extravasation. Her atraumatic subcapsular haematoma fulfils two out of three clinical features of Lenk's triad (acute flank pain, hypovolaemic shock), suggestive of Wunderlich syndrome...
March 5, 2024: BMJ Case Reports
https://read.qxmd.com/read/38435302/a-case-report-of-pseudomonas-citronellolis-and-escherichia-coli-isolated-from-acute-suppurative-appendicitis-reveals-the-potential-intestinal-colonization-and-pathogenicity-of-pseudomonas-citronellolis
#6
Yugui Lin, Yanfen Li, Chunxiu Lin
Human infections caused by Pseudomonas citronellolis , an environmental bacterium, are infrequent, with only two cases related to uncommon urinary tract infections and bacteremia reported in recent years. All these cases typically occurred in elderly patients with compromised or decreased immune function. Simultaneously, the epithelial barrier disruption induced by invasive biopsy procedures or gastrointestinal disorders such as gastroenteritis provided a pathway for Pseudomonas citronellolis to infiltrate the organism...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38391537/antimicrobial-agent-use-for-urinary-tract-infection-in-long-term-care-facilities-in-spain-results-from-a-retrospective-analytical-cohort-analysis
#7
JOURNAL ARTICLE
Priscila Matovelle, Bárbara Olivan-Blázquez, Rosa Magallón-Botaya, Ana García-Sangenís, Ramon Monfà, Rosa Morros, Alicia Navarro Sanmartín, Jesús Mateos-Nozal, Carmen Sáez Bejar, Consuelo Rodríguez Jiménez, Elena López Pérez, Carl Llor
Urinary tract infections (UTIs) are highly prevalent in long-term care facilities, constituting the most common infection in this setting. Our research focuses on analyzing clinical characteristics and antimicrobial prescriptions for UTIs in residents across nursing homes (NH) in Spain. This is a retrospective analytical cohort analysis using a multifaceted approach based on the normalization process theory to improve healthcare quality provided by nursing staff in 34 NHs in Spain. In this study, we present the results of the first audit including 719 UTI cases collected between February and April 2023, with an average age of 85...
February 3, 2024: Antibiotics
https://read.qxmd.com/read/38355490/risk-factors-and-prognosis-of-perioperative-acute-heart-failure-in-elderly-patients-with-hip-fracture-case-control-studies-and-cohort-study
#8
JOURNAL ARTICLE
Wei Zhao, Mingming Fu, Zhiqian Wang, Zhiyong Hou
BACKGROUND: Elderly patients with hip fracture who develop perioperative acute heart failure (AHF) have a poor prognosis. The aim of the present study is to investigate the potential risks of AHF in elderly hip-fracture patients in the postoperative period and to evaluate the prognostic significance of AHF. METHODS: A retrospective analysis was conducted on hip fracture patients at the Third Hospital of Hebei Medical University, who were continuously in hospital from September 2018 to August 2020...
February 15, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38333475/watery-diarrhea-is-not-always-clostridioides-difficile-a-case-report-of-aeromonas-hydrophila-gastroenteritis
#9
Sahrudh Dharanendra, Aaron S Gillet, Bashir Geer, Mary Ann Kirkconnell Hall, Patricia R Hwang
Aeromonas species can cause acute gastroenteritis but are much less commonly observed in the hospital setting than other bacteria. Most cases of Aeromonas hydrophila gastroenteritis reported in the literature have occurred in pediatric, elderly, and/or immunocompromised patients. We present a case of subacute watery diarrhea due to A. hydrophila infection in an otherwise healthy 48-year-old female patient with prior abdominal surgeries and recent hospitalization for a catheter-associated urinary tract infection (CAUTI) for which she received antibiotics...
January 2024: Curēus
https://read.qxmd.com/read/38327928/bacterial-diversity-and-antibiotic-resistance-patterns-of-community-acquired-urinary-tract-infections-in-mega-size-clinical-samples-of-egyptian-patients-a-cross-sectional-study
#10
JOURNAL ARTICLE
Amr Tarek, Salah Abdalla, Nehal A Dokmak, Ali A Ahmed, Taghrid S El-Mahdy, Nesreen A Safwat
BACKGROUND:  Community-acquired urinary tract infection (UTI) is one of the most common infectious diseases nowadays. Alarming increased levels of antimicrobial resistance are developing globally which limit treatment options and may lead to life-threatening problems. AIM: Our study aimed to collect surveillance data on non-hospitalized Egyptian UTI cases and to develop strategies against multidrug-resistant pathogens (MDR). According to our knowledge, this is the first study to screen this high number (15,252 urine samples) in a short period (three months), providing valuable data on resistance profiles in non-hospitalized Egyptian UTI patients...
January 2024: Curēus
https://read.qxmd.com/read/38317894/ecological-spectroscopic-methodologies-for-quantifying-co-administered-drugs-in-human-plasma-by-photochemical-quantum-mechanical-simulation
#11
JOURNAL ARTICLE
Maya S Eissa, Khaled Attala, Ahmed Elsonbaty, Aziza E Mostafa, Randa A Abdel Salam, Ghada M Hadad, Mohamed A Abdelshakour
Urinary tract infections (UTIs) constitute the second most prevalent bacterial infections in the elderly demographic. The treatment landscape involves various antibiotics targeting the causative organisms; nevertheless, the emergence of resistance significantly impacts therapeutic effectiveness. Presently, a fixed-dose pharmaceutical combination is advocated to optimize patient outcomes by mitigating the risks of bacterial resistance and associated side effects. Ofloxacin (OFL) and cefpodoxime proxetil (CPD) combinations, co-administered with flavoxate hydrochloride (FLV), have demonstrated efficacy in UTI cases, offering relief from concomitant symptoms...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38315025/photochemical-inactivation-as-an-alternative-method-to-produce-a-whole-cell-vaccine-for-uropathogenic-escherichia-coli-upec
#12
JOURNAL ARTICLE
Marlena M Westcott, Alexis E Morse, Gavin Troy, Maria Blevins, Thomas Wierzba, John W Sanders
Uropathogenic Escherichia coli (UPEC) is the primary causative agent of lower urinary tract infection (UTI). UTI presents a serious health risk and has considerable secondary implications including economic burden, recurring episodes, and overuse of antibiotics. A safe and effective vaccine would address this widespread health problem and emerging antibiotic resistance. Killed, whole-cell vaccines have shown limited efficacy to prevent recurrent UTI in human trials. We explored photochemical inactivation with psoralen drugs and UVA light (PUVA), which crosslinks nucleic acid, as an alternative to protein-damaging methods of inactivation to improve whole-cell UTI vaccines...
February 5, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38312266/six-item-modified-frailty-index-independently-predicts-complications-following-total-shoulder-arthroplasty
#13
JOURNAL ARTICLE
Kenny Ling, Justice U Achonu, Robert Martino, Steven H Liu, David E Komatsu, Edward D Wang
BACKGROUND: In the realm of orthopedic surgery, frailty has been associated with higher rates of complications following total hip and total knee arthroplasties. Among various measures of frailty, the Six-Item Modified Frailty Index (MF-6) has recently gained popularity as a predictor for postoperative complications. The purpose of this study was to investigate MF-6 as a predictor for early postoperative complications in the elderly patient population following total shoulder arthroplasty (TSA)...
January 2024: JSES international
https://read.qxmd.com/read/38289324/should-hormone-replacement-therapy-any-route-of-administration-be-considered-in-all-postmenopausal-women-with-lower-urinary-tract-symptoms-report-from-the-ici-rs-2023
#14
REVIEW
Annika Taithongchai, Rayan Mohamed-Ahmed, Sanjay Sinha, William Gibson, Ilias Giarenis, Dudley Robinson, Paul Abrams
AIMS: This International Consultation on Incontinence-Research Society report aims to summarize the evidence and uncertainties regarding the use of hormone replacement therapy by any route in the management of lower urinary tract symptoms (LUTS) including recurrent urinary tract infections (rUTI), with a review of special considerations for the elderly. Research question proposals to further this field have been highlighted. METHODS: An overview of the existing evidence, guidelines, and consensus regarding the use of topical or systemic estrogens in the management of LUTS...
January 30, 2024: Neurourology and Urodynamics
https://read.qxmd.com/read/38267801/clinical-presentation-and-antimicrobial-resistance-of-invasive-escherichia-coli-disease-in-hospitalized-older-adults-a-prospective-multinational-observational-study
#15
JOURNAL ARTICLE
Joachim Doua, Jesús Rodríguez-Baño, Rachel Froget, Padma Puranam, Oscar Go, Jeroen Geurtsen, Sanne van Rooij, Tuba Vilken, Inage Minoru, Izumi Yasumori, Bart Spiessens, Evelina Tacconelli, Lena M Biehl, Joshua T Thaden, Michal Sarnecki, Herman Goossens, Jan Poolman, Marc Bonten, Miquel Ekkelenkamp
BACKGROUND: Clinical data characterizing invasive Escherichia coli disease (IED) are limited. We assessed the clinical presentation of IED and antimicrobial resistance (AMR) patterns of causative E. coli isolates in older adults. METHODS: EXPECT-2 (NCT04117113) was a prospective, observational, multinational, hospital-based study conducted in patients with IED aged ≥ 60 years. IED was determined by the microbiological confirmation of E...
January 25, 2024: Infection
https://read.qxmd.com/read/38197977/population-based-genomic-surveillance-of-pseudomonas-aeruginosa-causing-bloodstream-infections-in-a-large-canadian-health-region
#16
JOURNAL ARTICLE
Gisele Peirano, Yasufumi Matsumara, Diego Nobrega, Deirdre Church, Johann D D Pitout
PURPOSE: Population-based surveillance was undertaken to determine clinical factors, susceptibility patterns, and incidence rates (IR) of Pseudomonas aeruginosa causing bloodstream infections (BSIs) in a Canadian region (2010-2018). METHODS: We combined clinical data with genomics to characterize P. aeruginosa (BSIs) (n = 167) in a well-defined Canadian (Calgary) human population over a 9-year period (2010-2018). RESULTS: The annual population IR per 100,000 patient years increased from 3...
January 10, 2024: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/38180102/older-versus-younger-patients-in-robot-assisted-radical-cystectomy-with-intracorporeal-ileal-conduit-comparing-safety-and-clinical-outcomes
#17
JOURNAL ARTICLE
Dutsadee Sowanthip, Kenji Zennami, Tanan Bejrananda, Takuhisa Nukaya, Masashi Takenaka, Manabu Ichino, Kiyoshi Takahara, Hitomi Sasaki, Mamoru Kusaka, Makoto Sumitomo, Ryoichi Shiroki
OBJECTIVE: To evaluate the safety and efficacy of robot-assisted radical cystectomy using an intracorporeal ileal conduit in older compared to younger patients. METHODS: We retrospectively analyzed 122 patients who underwent robot-assisted radical cystectomy with an intracorporeal ileal conduit at Fujita Health University Hospital and Fujita Health University Okazaki Medical Center between 2012 and 2022. Patients were categorized into two groups: older (age ≥ 75 years; n = 53) and younger (age < 75 years; n = 69)...
January 5, 2024: International Journal of Urology: Official Journal of the Japanese Urological Association
https://read.qxmd.com/read/38161563/purple-urine-bag-syndrome-a-peculiar-presentation-of-a-urinary-tract-infection
#18
João Faia, Ana S Martins, Miguel Martins
Purple urine bag syndrome (PUBS) is a peculiar phenomenon and corresponds to the appearance of purplish-colored urine. It is associated with urinary tract infections occurring mainly in debilitated elderly women with constipation and long-term indwelling urinary catheters. We share a case involving PUBS in an 87-year-old female patient, explore the pathophysiology, and discuss potential management options for this uncommon syndrome.
December 2023: Curēus
https://read.qxmd.com/read/38138052/acute-pyelonephritis-with-bacteremia-in-an-89-year-old-woman-caused-by-two-slow-growing-bacteria-aerococcus-urinae-and-actinotignum-schaalii
#19
Laurène Lotte, Claire Durand, Alicia Chevalier, Alice Gaudart, Yousra Cheddadi, Raymond Ruimy, Romain Lotte
Aerococcus urinae is an aerobic Gram-positive coccus that grows as tiny alpha-hemolytic colonies. Actinotignum schaalii is a slow-growing facultative anaerobic Gram-positive rod. These bacteria are part of the urogenital microbiota of healthy patients, but can also be involved in urinary tract infections (UTIs), particularly in elderly men and young children. Because A. urinae and A. schaalii are fastidious and are difficult to identify with phenotypic methods, they are underestimated causes of UTIs. Their growth is slow and requires a blood-enriched medium incubated under an anaerobic or 5% CO2 atmosphere for 48 h and from 24 to 48 h for A...
December 2, 2023: Microorganisms
https://read.qxmd.com/read/38137964/evaluation-of-extended-spectrum-beta-lactamase-resistance-in-uropathogenic-escherichia-coli-isolates-from-urinary-tract-infection-patients-in-al-baha-saudi-arabia
#20
JOURNAL ARTICLE
Samiyah Ahmad Abdullah Alghamdi, Shazia Shaheen Mir, Fayez Saad Alghamdi, Mohammad Abdul Majeed Mohammad Aref Al Banghali, Shaia Saleh Rajab Almalki
Urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms are prevalent in both outpatient and inpatient settings, representing the most often encountered forms of infection. This research aimed to estimate the prevalence of ESBL-UTIs along with other uropathogens in the adult population and to assess the antibiotic activity against Escherichia coli extended-spectrum beta-lactamase ( E. coli ESBL) isolates from patient samples in Al-Baha. A retrospective cross-sectional study included patients who presented to King Fahad Hospital in Al-Baha with clinical suspicion of UTI between 1 January 2019 and 30 September 2022...
November 21, 2023: Microorganisms
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