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https://www.readbyqxmd.com/read/29792954/increased-brain-docosahexaenoic-acid-has-no-effect-on-the-resolution-of-neuroinflammation-following-intracerebroventricular-lipopolysaccharide-injection
#1
Marc-Olivier Trépanier, Kathryn E Hopperton, Vanessa Giuliano, Mojgan Masoodi, Richard P Bazinet
Resolution of inflammation in the periphery was once thought to be a passive process, but new research now suggests it is an active process mediated by specialized pro-resolving lipid mediators (SPM) derived from omega-3 polyunsaturated fatty acids (n-3 PUFA). However, this has yet to be illustrated in neuroinflammation. The purpose of this study was to measure resolution of neuroinflammation and to test whether increasing brain docosahexaenoic acid (DHA) affects the resolution of neuroinflammation. C57Bl/6 mice, fat-1 mice and their wildtype littermates, fed either fish oil or safflower oil, received lipopolysaccharide (LPS) in the left lateral ventricle...
May 21, 2018: Neurochemistry International
https://www.readbyqxmd.com/read/29790089/red-drum-sciaenops-ocellatus-growth-and-expression-of-bile-salt-dependent-lipase-in-response-to-increasing-dietary-lipid-supplementation
#2
Mayra L González-Félix, Delbert M Gatlin, Martin Perez-Velazquez, Ken Webb, Armando García-Ortega, Michael Hume
Sciaenops ocellatus has a long history in aquaculture and many difficulties associated with its commercial culture have been addressed and successfully resolved; nevertheless, further research in lipid nutrition could address more comprehensive questions on the way these nutrients are utilized. The purpose of this study was to evaluate S. ocellatus growth and lipase gene expression in response to increasing dietary lipid supplementation. Four experimental diets were formulated to provide 3, 10, 16, or 23% lipid using menhaden fish oil...
May 22, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29787602/endocrine-disrupting-potency-of-organic-pollutant-mixtures-isolated-from-commercial-fish-oil-evaluated-in-yeast-based-bioassays
#3
Marek Łukasz Roszko, Marta Kamińska, Krystyna Szymczyk, Katarzyna Piasecka-Jóźwiak, Beata Chabłowska
The aim of this work was to evaluate the activity of xenobiotic mixtures containing persistent organic pollutants isolated from commercial fish oil samples against sex hormone receptors, including estrogen and androgen. The applied bioassay was based on transgenic yeast strains. The mixtures were extracted from the samples using the semi-permeable membrane dialysis technique and analyzed with gas chromatography/ion trap mass spectrometry. It turned out that mixtures of chemicals isolated from fish oil may interact with human steroid sex hormone receptors in various ways: the tested samples showed both estrogenic and anti-androgenic activity...
2018: PloS One
https://www.readbyqxmd.com/read/29784318/effect-of-spray-drying-with-organic-solvents-on-the-encapsulation-release-and-stability-of-fish-oil
#4
Cristian Encina, Gloria Márquez-Ruiz, Francisca Holgado, Begoña Giménez, Cristina Vergara, Paz Robert
Fish-oil (FO) was encapsulated with hydroxypropylcelullose (HPC) by conventional spray-drying with water (FO-water) and solvent spray-drying with ethanol (FO-EtOH), methanol (FO-MeOH) and acetone (FO-Acet) in order to study the effect of the solvent on the encapsulation efficiency (EE), microparticle properties and stability of FO during storage at 40 °C. Results showed that FO-Acet presented the highest EE of FO (92.0%), followed by FO-EtOH (80.4%), FO-MeOH (75.0%) and FO-water (71.1%). A decrease of the dielectric constant increased the EE of FO, promoting triglyceride-polymer interactions instead of oil-in-water emulsion retention...
October 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29784296/the-effect-of-rosemary-rosmarinus-officinalis-l-extract-on-the-oxidative-stability-of-lipids-in-cow-and-soy-milk-enriched-with-fish-oil
#5
Xujian Qiu, Charlotte Jacobsen, Ann-Dorit Moltke Sørensen
Lipid oxidation of fish oil enriched cow milk and soy milk supplemented with rosemary extract stored at 2 °C was studied. Both peroxide value and volatile secondary lipid oxidation products were determined to monitor the progress of lipid oxidation. Rosemary extract inhibited lipid oxidation in fish oil enriched cow milk. In contrast, soy milk samples having much higher unsaturated fatty acid content showed higher lipid oxidation stability compared to cow milk. Reduction in the content of chlorogenic acid during storage suggested that this compound may contribute to the lipid oxidation stability of fish oil enriched soy milk product...
October 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29783628/is-3-carboxy-4-methyl-5-propyl-2-furanpropionate-cmpf-a-clinically-relevant-uremic-toxin-in-haemodialysis-patients
#6
Mathilde Luce, Anais Bouchara, Myriam Pastural, Samuel Granjon, Jean Christophe Szelag, Maurice Laville, Walid Arkouche, Denis Fouque, Christophe O Soulage, Laetitia Koppe
3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) is a metabolite of furan fatty acid and a marker of fish oil intake. CMPF is described as a protein-bound uremic toxin and interacts with free oxygen radicals, which can induce cell damages. However, the clinical consequences of CMPF accumulation in haemodialysis patients remain poorly documented. The aims of this study are to investigate potential association between CMPF levels and (i) biochemical and nutritional parameters; (ii) cardiovascular events and (iii) mortality...
May 18, 2018: Toxins
https://www.readbyqxmd.com/read/29781483/dose-dependent-effects-of-fish-oil-on-cardio-metabolic-biomarkers-in-healthy-middle-aged-and-elderly-chinese-people-a-double-blind-randomized-controlled-trial
#7
Jia Song, Manjiang Hu, Cheng Li, Bo Yang, Qing Ding, Chunhong Wang, Limei Mao
n-3PUFA consumption has been widely accepted as a nutritional strategy for the secondary prevention of cardiovascular events in patients at high risk of cardiovascular disease (CVD), but little is known about the dose-response relationship between dietary n-3PUFA and serum biomarkers associated with cardiovascular health in the general population. The present study involved a 12-week double-blind, randomized controlled trial to explore the effects of fish oil with different doses (0.31, 0.62 and 1.24 g d-1 of EPA and DHA) on serum fatty acids and cardio-metabolic biomarkers including adiponectin, inflammatory markers, lipid profiles and fasting glucose in healthy middle-aged and elderly Chinese people...
May 21, 2018: Food & Function
https://www.readbyqxmd.com/read/29778078/an-effective-and-low-cost-carbon-based-clean-up-method-for-pcdd-fs-and-pcbs-analysis-in-food
#8
Kleopatra Kedikoglou, Danae Costopoulou, Irene Vassiliadou, Evangelos Bakeas, Leondios Leondiadis
Sample preparation is of critical importance in dioxin analysis of food and feed samples. It is a complex procedure that includes lipid extraction followed by the application of chromatographic separation techniques, aiming in removing undesirable interferences from the matrix. The separation of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) from polychlorinated biphenyls (PCBs) is achieved by carbon-based materials which should have high fat capacity in order to be suitable for lipid-containing matrices...
May 7, 2018: Chemosphere
https://www.readbyqxmd.com/read/29778059/tracking-pollutants-in-dietary-fish-oil-from-ocean-to-table
#9
Sheng-Xiang Sun, Xue-Ming Hua, Yun-Yun Deng, Yun-Ni Zhang, Jia-Min Li, Zhao Wu, Samwel Mchele Limbu, Da-Sheng Lu, Hao-Wen Yin, Guo-Quan Wang, Rune Waagbø, Frøyland Livar, Mei-Ling Zhang, Zhen-Yu Du
Dietary fish oil used in aquafeed transfers marine pollutants to farmed fish. However, the entire transfer route of marine pollutants in dietary fish oil from ocean to table fish has not been tracked quantitatively. To track the entire transfer route of marine pollutants from wild fish to farmed fish through dietary fish oil and evaluate the related human health risks, we obtained crude and refined fish oils originating from the same batch of wild ocean anchovy and prepared fish oil-containing purified aquafeeds to feed omnivorous lean Nile tilapia and carnivorous fatty yellow catfish for eight weeks...
May 16, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29776922/core-vs-diet-associated-and-postprandial-bacterial-communities-of-the-rainbow-trout-oncorhynchus-mykiss-midgut-and-feaces
#10
Eleni Mente, Eleni Nikouli, Efthimia Antonopoulou, Samuel A M Martin, Konstantinos Ar Kormas
This study investigated the impact of different dietary ingredients with different protein/lipid sources on the midgut and feaces bacteria communities structure just before feeding and 3h after feeding a single meal on rainbow trout ( Oncorhynchus mykiss ) individuals. Fish were kept in experimental rearing facilities and fed ad libitum two times daily for five weeks. Fish were fed three different commercial diets containing a higher marine fishmeal/fish oil and a lower marine fishmeal/fish oil content. DNA was extracted from midgut and faeces samples for the analysis of their bacterial 16S rRNA gene diversity by targeting the V3-V4 region with 454 pyrosequencing...
May 18, 2018: Biology Open
https://www.readbyqxmd.com/read/29775616/amelioration-of-uvb-induced-oxidative-stress-and-inflammation-in-fat-1-transgenic-mouse-skin
#11
Hye-Won Yum, Seong Hoon Kim, Jing X Kang, Young-Joon Surh
ω-3 polyunsaturated fatty acids (PUFAs), which are abundant in some fish oils, are known to scavenge lipid peroxyl radicals and increase host immunoresponsiveness. As UVB-induced oxidative stress and inflammation have been implicated in apoptotic cell death, this study was designed to investigate the anti-inflammatory, anti-oxidative, and anti-apoptotic capacity of fat-1 transgenic mice capable of converting ω-6 to ω-3 PUFAs. Wild-type (WT) C57BL/6 mice and fat-1 mice were maintained on the AIN-93 diet supplemented with 10% safflower oil rich in ω-6 PUFAs for 5 weeks...
May 15, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29773586/seafood-long-chain-n-3-polyunsaturated-fatty-acids-and-cardiovascular-disease-a-science-advisory-from-the-american-heart-association
#12
REVIEW
Eric B Rimm, Lawrence J Appel, Stephanie E Chiuve, Luc Djoussé, Mary B Engler, Penny M Kris-Etherton, Dariush Mozaffarian, David S Siscovick, Alice H Lichtenstein
Since the 2002 American Heart Association scientific statement "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease," evidence from observational and experimental studies and from randomized controlled trials continues to emerge to further substantiate the beneficial effects of seafood long-chain n-3 polyunsaturated fatty acids and cardiovascular disease. A recent American Heart Association science advisory addressed the specific effect of n-3 polyunsaturated fatty acid supplementation on clinical cardiovascular events...
May 17, 2018: Circulation
https://www.readbyqxmd.com/read/29770449/effects-of-a-nanoemulsion-with-copaifera-officinalis-oleoresin-against-monogenean-parasites-of-colossoma-macropomum-a-neotropical-serrasalmidae
#13
D S S Valentim, J L Duarte, A E M F M Oliveira, R A S Cruz, J C T Carvalho, C Solans, C P Fernandes, M Tavares-Dias
Monogeneans are ectoparasites that may cause losses in production and productivity in the aquaculture of Colossoma macropomum. Chemotherapeutics used in aquaculture usually have major adverse effects on fish; hence, the use of essential oils has been considered advantageous, but these are not soluble in water. Thus, the use of nanostructures to enhance water solubility of compounds and improve bioactivity may be very promising. This study investigated the antiparasitic activity of nanoemulsion prepared with Copaifera officinalis oleoresin (50, 100, 150, 200 and 300 mg/L), against monogenean parasites from the gills of C...
May 16, 2018: Journal of Fish Diseases
https://www.readbyqxmd.com/read/29769748/comparative-ecologic-relationships-of-saturated-fat-sucrose-food-groups-and-a-mediterranean-food-pattern-score-to-50-year-coronary-heart-disease-mortality-rates-among-16-cohorts-of-the-seven-countries-study
#14
Daan Kromhout, Alessandro Menotti, Adalberta Alberti-Fidanza, Paolo Emilio Puddu, Peter Hollman, Anthony Kafatos, Hanna Tolonen, Hisashi Adachi, David R Jacobs
BACKGROUND/OBJECTIVES: We studied the ecologic relationships of food groups, macronutrients, eating patterns, and an a priori food pattern score (Mediterranean Adequacy Index: MAI) with long-term CHD mortality rates in the Seven Countries Study. SUBJECTS/METHODS: Sixteen cohorts (12,763 men aged 40-59 years) were enrolled in the 1960s in seven countries (US, Finland, The Netherlands, Italy, Greece, former Yugoslavia: Croatia/Serbia, Japan). Dietary surveys were carried out at baseline and only in a subsample of each cohort...
May 17, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29769200/long-chain-n-3-fatty-acids-attenuate-oncogenic-kras-driven-proliferation-by-altering-plasma-membrane-nanoscale-proteolipid-composition
#15
Natividad R Fuentes, Mohamed Mlih, Rola Barhoumi, Yang-Yi Fan, Paul Hardin, Trevor J Steele, Spencer Behmer, Ian A Prior, Jason Karpac, Robert S Chapkin
Ras signaling originates from transient nanoscale compartmentalized regions of the plasma membrane composed of specific proteins and lipids. The highly specific lipid composition of these nanodomains, termed nanoclusters, facilitates effector recruitment and therefore influences signal transduction. This suggests that Ras nanocluster proteolipid composition could represent a novel target for future chemoprevention interventions. There is evidence that consumption of fish oil containing long-chain n-3 polyunsaturated fatty acids (n-3 PUFA) such as eicosapentaenoic acid (EPA, 20:5Δ5,8,11,14,17) and docosahexaenoic acid (DHA, 22:6Δ4,7,10,13,16,19) may reduce colon cancer risk in humans, yet the mechanism underlying this effect is unknown...
May 16, 2018: Cancer Research
https://www.readbyqxmd.com/read/29767094/effect-of-dietary-incorporation-of-n-3-polyunsaturated-fatty-acids-rich-oil-sources-on-fatty-acid-profile-keeping-quality-and-sensory-attributes-of-broiler-chicken-meat
#16
Sridhar Kalakuntla, Nalini K Nagireddy, Arun K Panda, Narasimha Jatoth, Raghunandan Thirunahari, Ravinder R Vangoor
The present study was undertaken to investigate the effect of dietary replacement of commonly used vegetable oil (sunflower oil, SFO) with n-3 polyunsaturated fatty acids (PUFA) rich oil sources on broiler chicken performance, carcass yield, meat fatty acid composition, keeping quality and sensory attributes of meat. In the current experiment, 300 day-old Krishibro broiler chicks were randomly distributed to 5 dietary groups (50 replicates with 6 chicks in each) prepared by replacing SFO (2% and 3% of diet during starter and finisher periods, respectively) with n-3 PUFA rich soybean oil (SO), mustard oil (MO), linseed oil (LO) or fish oil (FO) on weight basis...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29766417/the-fto-gene-is-associated-with-growth-and-omega-3-6-ratio-in-asian-seabass
#17
Fei Sun, Rongjian Tu, Jun Hong Xia, Xiao Jun Liu, Gen Hua Yue
Polymorphisms in the FTO gene are associated with obesity and body mass index in humans and livestock. Little information of whether FTO plays an important role in aquaculture fish species is available. We cloned and characterized the FTO gene in an economically important food fish species: Asian seabass (Lates calcarifer). The full-length cDNA of the gene is 3679 bp, containing an ORF of 1935 bp encoding 644 amino acids, a 216 bp 5' UTR and a 1538 bp 3' UTR. The gene consisted of nine exons and eight introns and was 117,679 bp in length...
May 16, 2018: Marine Biotechnology
https://www.readbyqxmd.com/read/29765320/distinct-analgesic-actions-of-dha-and-dha-derived-specialized-pro-resolving-mediators-on-post-operative-pain-after-bone-fracture-in-mice
#18
Linlin Zhang, Niccolò Terrando, Zhen-Zhong Xu, Sangsu Bang, Sven-Eric Jordt, William Maixner, Charles N Serhan, Ru-Rong Ji
Mechanisms of pain resolution are largely unclear. Increasing evidence suggests that specialized pro-resolving mediators (SPMs), derived from fish oil docosahexaenoic acid (DHA), promote the resolution of acute inflammation and potently inhibit inflammatory and neuropathic pain. In this study, we examined the analgesic impact of DHA and DHA-derived SPMs in a mouse model of post-operative pain induced by tibial bone fracture (fPOP). Intravenous perioperative treatment with DHA (500 μg), resolvin D1 (RvD1, 500 ng) and maresin 1 (MaR1, 500 ng), 10 min and 24 h after the surgery, delayed the development of fPOP (mechanical allodynia and cold allodynia)...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29762043/the-effects-of-fish-oil-on-hiv-related-inflammation-and-markers-of-immunosenescence-a-randomized-clinical-trial
#19
Barbara Swanson, Joyce Keithley, Linda Baum, Sue Leurgans, Oluwatoyin Adeyemi, Lisa L Barnes, Mariana Mata, Anneliese Rosdil
OBJECTIVE: To explore the safety and efficacy of fish oil to modulate parameters of inflammation and immunosenescence in HIV-infected older adults. DESIGN: This study uses a randomized, controlled, double-blind clinical trial. SETTING: The study was conducted in an outpatient HIV/AIDS clinic in a large urban Midwestern city in the United States. SUBJECTS: A total of 37 clinically stable HIV-infected adults between the ages of 40 and 70 years of age participated...
May 15, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29761493/experimental-induction-of-mouthrot-in-atlantic-salmon-smolts-using-tenacibaculum-maritimum-from-western-canada
#20
K Frisch, S B Småge, C Vallestad, H Duesund, Ø J Brevik, A Klevan, R H Olsen, S T Sjaatil, D Gauthier, B Brudeseth, A Nylund
Mouthrot, or bacterial stomatitis, is a disease which mainly affects farmed Atlantic salmon, (Salmo salar, L.), smolts recently transferred into salt water in both British Columbia (BC), Canada, and Washington State, USA. It is a significant fish welfare issue which results in economic losses due to mortality and antibiotic treatments. The associated pathogen is Tenacibaculum maritimum, a bacterium which causes significant losses in many species of farmed fish worldwide. This bacterium has not been proven to be the causative agent of mouthrot in BC despite being isolated from affected Atlantic salmon...
May 14, 2018: Journal of Fish Diseases
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